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Engineering catalyst interfaces plays a key role in designing supported metal systems. Here, the authors report that Ni nanoparticles redisperse from SiO₂ to molybdenum carbide, forming dual interfaces that enhance tandem CO₂ hydrogenation.

Global analysis of obesity trends from 1980 to 2024 in 200 countries and territories using data from 4,050 population-based studies reveals that framing obesity as a single global epidemic masks the highly varied dynamics across countries and age groups.

Low-temperature CO₂ methanation processes have potential for improved energy efficiency due to high equilibrium conversion but are generally limited by poor catalyst activity. Here the authors report an inverse CeZrO_x/Ni catalyst that realizes high low-temperature (200 °C) methanation activity at ambient pressure.

Sustainable hydrogen production requires efficient oxygen evolution catalysts. Here, the authors identify non-noble single-atom catalysts via machine learning-assisted computational screening and reveal their active-site mechanisms for high-performance anion exchange membrane water electrolysis.

Biomass conversion holds promise as a more sustainable source of platform chemicals, but limitations in the ways in which lignin can be broken down is a current bottleneck. Here the authors report an electrocatalytic hydrogenolysis over skeletal Ni that cleaves diaryl ethers, chemically resistant moieties in both renewable carbon sources and persistent organic pollutants.

Understanding the growth pathway of faceted alloy nanoparticles at the atomic level is crucial to morphology control and property tuning, but remains a challenge. Here, the authors reveal the particle growth and facet formation mechanisms of octahedral Pt₃Ni nanoparticles using multiple cutting-edge in situ techniques.

XRISM spectroscopy of the nucleus of the Circinus galaxy indicates elemental abundances suggestive of a dominant enrichment from core-collapse supernovae with progenitors below 20 solar masses; more massive stars may directly collapse into black holes.

This study presents a stable and efficient photoelectrochemical system for nitrate reduction to ammonia using metal catalysts on GaN/Si photoelectrodes, offering valuable insights into catalyst design for sustainable ammonia production driven by solar energy.

Genome-wide association analyses identify new risk loci for heart failure and its subtypes, extending understanding of the underlying biological pathways and disease mechanisms.

Dicarbofunctionalization of nonactivated alkenes is a simple way to rapidly build molecular complexity, but these transformations have not been extensively explore under metallaphotoredox conditions. Here, the authors develop a nickel/photoredox dual catalytic system for arylalkylation of alkenes.

Here the authors identify a tumor immunoevasion mechanism in which tumor cells release branched-chain amino acid metabolites that can bind and activate Notch on tumor-associated macrophages, reprogramming these cells to be immunosuppressive.

Direct electroreduction of dilute CO₂ in flue gas streams is challenging due to the presence of O₂ impurities. Here the authors demonstrate that an acidic electrolyte can overcome this challenge, enabling the generation of multicarbon products from simulated flue gas at reasonable rates.

Mapping binding sites using photoaffinity labelling (PAL) is highly valuable but challenging for probe and drug discovery campaigns. Now a chemoproteomic approach has been developed that incorporates cleavable silyl ether linkages into PAL probes to pinpoint and quantify the precise sites where small molecules engage protein binding partners.

Modulating interfacial electric fields provides a means to control electrocatalyst activity for a broad range of reactions. Here the authors show that this can be achieved by tuning the nanocurvature of carbon supported single-atom catalysts.

Protein phosphatase 5 (PP5) is highly conserved across eukaryotes. Yan et al. show that de-repression of PP5 by the chaperone organizer HOP1 activates NLR-mediated autoimmunity through dephosphorylation of the protein kinase CRCK3 in Arabidopsis.

Self-passivation in metallic alloys is a fundamental issue for corrosion and oxidation resistance. Here, authors demonstrate crystal facet-dependent initial oxidation behavior in a model Ni-Cr alloy, using in situ environmental TEM and DFT calculations. They show that the (001) facet exhibits incipient oxidation resistance compared to the (111) facet.

Efficient storage of crude hydrogen, through toluene hydrogenation to methylcyclohexane, is often inhibited by CO impurities. Here, the authors develop a RuNi/TiO₂ catalyst which avoids deactivation through promoting simultaneous CO methanation.

Charge-to-spin conversion is critical element for spintronic devices. In most materials, there are several sources of charge-to-spin conversion, which are often challenging to disentangle. Here, Chen et al succeed in disentangling spin Hall and Rashba-Edelstein contributions to charge-to-spin conversion in ultrathin MoTe2 using position dependent measurements of the current-induced spin accumulation.

Global trade tightly links water, energy and food systems, but its effects on cross-border sustainability and equity remain unclear. A study now maps global water–energy–food trade networks, finding that trade balances overall resource gains while deepening cross-country income inequalities.

Streptococcus thermophilus phages circumvent host CRISPR defences via AcrIIIA2, which complexes with enolase, a highly abundant glycolysis enzyme, to block phage RNA binding.

Epigenetic profiles can be predictive of macrophage transcriptional responses to influenza A virus infection in individuals of European and African ancestry. Ancestry-linked epigenetic differences appear to be genetically controlled.

Removing trace acetylene from ethylene is vital for plastic production, yet catalysts often overreact and waste the product. This work reveals that palladium dual-atom catalyst on carbon greatly speeds the reaction while keeping ethylene intact.

To optimize the interfacial quality and electrode magnetism in spintronic devices, the authors develop an electrode transfer technique that can greatly improve device interfacial quality, performance and reproducibility, universal to various spacers.

ThermoCas9, a genome-editing enzyme that is sensitive to the DNA methylation status of the target locus, is characterized and shows promise for targeting hypomethylated DNA regions in cancer cells.

Bacterial ribonucleoprotein bodies are dynamic biomolecular condensates that play roles in RNA metabolism. Here, Ortiz-Rodríguez et al. show that, under stress, these condensates shift from a liquid state to a rigid state and switch their function from mRNA decay to mRNA storage, thus enabling transcript preservation and rapid recovery upon nutrient replenishment.

The transcription factor SlWRI3 integrates fatty acid metabolism with acylsugar biosynthesis in tomato trichomes, coordinating precursor supply and assembly of these natural insect defensive chemicals.

Templates with two distinct sets of pores allow the fabrication of nanostructured surfaces with different morphologies and materials.

Imprinting by influenza viruses can cause a deleterious shift of nearly the entire memory recall response against key, conserved epitopes.

H₂ is regarded as an attractive green fuel and a promising energy carrier for the future. Here, the promotion functions of reverse spillover effects in the H₂ generation reactions over bicomponent catalysts are revealed by performing in situ X ray absorption near edge structure characterization.

While nonenzymatic organic synthesis from the H₂–CO₂ redox couple underpins prebiotic carbon metabolism, building integrated, multi-pathway carbon reaction networks prior to enzymatic catalysis remains challenging. Here, the authors show that metallic molybdenum sulfide, mimicking Mo–S₂–pterin enzymes, enables hydrothermal CO₂ reaction networks spanning five carbon sequestration pathways.

Strong correlations between electrons in topological surface states drive the formation of surface van Hove singularities. These may be linked to charge density waves in the surface states.

Industrial hydrogen production often uses carbon-based sources, necessitating complex purification processes to separate hydrogen from impurities. Here the authors present a reversible catalytic cycle that converts crude hydrogen into pure hydrogen, bypassing the need for pressure swing adsorption or membrane systems.

The study of covalent organic frameworks (COFs) in electrocatalytic CO₂ reduction reaction (CO₂RR) has drawn much attention. Here the authors show a series of tetrathiafulvalene based COFs designed and exfoliated into nanosheets which exhibit high electrocatalytic CO₂RR performance.

School closures in municipalities in Japan at the start of the COVID-19 pandemic showed no significant reduction in cases compared with case counts in municipalities with open schools, questioning the utility of school closures in mitigating community spread of severe acute respiratory syndrome coronavirus 2.

PPARγ regulates glucose and lipid metabolism, yet safer PPARγ-targeted insulin sensitizers are needed to treat metabolic disorders. Here, Kuang-Ting et al. elucidate structure–function relationships of non-covalent inverse agonists that enhance receptor binding and improve insulin sensitivity, providing a framework for next-generation drug design.

Electrosynthesis of higher carbon products (C₄₊) in a high selectivity has not been achieved by the direct reduction of CO₂ or CO. Here, the authors use a cascade electrocatalysis–thermocatalysis approach to produce butane from CO with an overall selectivity of 43%.

Kaposi’s Sarcoma-associated Herpesvirus encodes ORF74, a GPCR driving oncogenesis through high basal signaling. Here, authors present cryoEM structures of both inactive and active states, revealing the structural basis for its ligand promiscuity and spontaneous activation.

Proton radioactivity is useful for studying nuclear structure. Here the authors report two proton emission branches from the 10+ state isomer of 54mNi by using a time projection chamber.

The authors report a superconducting transition beginning at 13 K in films of the quintuple-layer nickelate Nd₆Ni₅O₁₂.

Quasicrystals exhibit long-range order without periodicity. The authors report an approach for quasicrystal fabrication and show through in situ imaging and corresponding simulations the formation of a single decagonal quasicrystal arising from coalescence of multiple quasicrystals in a liquid.