Family history of premature coronary artery disease is a well-recognized, but under-recorded, risk factor that captures the complex interplay among shared genetic, environmental and lifestyle factors within families. Here, Lan et al. review the mechanisms of inherited risk, discuss the current limitations of family history in risk stratification models and outline future directions for precision care in families with a history of premature coronary artery disease.
- Nick S. R. Lan
- Girish Dwivedi
- Abdul Rahman Ihdayhid