Nature Search

Screening of five mulberry (Morus spp.) cultivars for safe utilization of arsenic-contaminated tailings

Fuping Lu
Chunbiao Wu
Shuchang Wang
ResearchOpen Access02 Apr 2026
Scientific Reports

P: 1-13
Androgen activity in the male embryonic hindbrain drives lethal PFA ependymoma

Androgen activity in the male embryonic hindbrain prolongs hindbrain differentiation in male individuals and drives sex differences in the incidence and prognosis of posterior fossa type A (PFA) ependymoma, an aggressive childhood brain tumour.

Jiao Zhang
Winnie Ong
Michael D. Taylor
ResearchOpen Access25 Mar 2026
Nature

P: 1-11
Combining AI to reveal CCDC3-mediated pathways of colorectal cancer liver metastasis

Runze Huang
Qinyu Liu
Weiping Zhu
ResearchOpen Access07 Mar 2026
npj Digital Medicine

P: 1-16
Seepage characteristics of fractured sandstone under deep high-confined water and mining-induced stress

Hongsheng Tu
Runze Wu
Cun Zhang
ResearchOpen Access01 Mar 2026
Scientific Reports

P: 1-18
Biocatalytic, stereoconvergent alkylation of (Z/E)-trisubstituted silyl enol ethers

Biocatalytic strategies typically transform only one alkene isomer into products, limiting the yield. Now a biocatalyst is reported to convert both isomeric silyl enol ethers into chiral α-branched ketones with high efficiency and excellent selectivity.

Runze Mao
Doris Mia Taylor
Frances H. Arnold
Research02 Nov 2023
Nature Synthesis

Volume: 3, P: 256-264
ADSL promotes autophagy and tumor growth through fumarate-mediated Beclin1 dimethylation

Protein kinase R-like endoplasmic reticulum kinase-phosphorylated adenylosuccinate lyase (ADSL) binds to Beclin1 upon lipid deprivation. ADSL-produced fumarate increases Beclin1 K117 dimethylation by inhibiting lysine demethylase 8 activity, resulting in disrupted binding of BCL-2 to Beclin1, enhanced autophagy and liver tumor growth.

Lei Wang
Runze Shi
Daqian Xu
Research29 Jan 2025
Nature Chemical Biology

Volume: 21, P: 894-905
Advances in the mechanism for steroid-induced osteonecrosis of the femoral head

Runze Zhou
Yixin Bian
Xisheng Weng
ReviewsOpen Access12 Feb 2026
Bone Research

Volume: 14, P: 1-31
In situ gut microbiota editing: enhancing therapeutic efficacy for bacterial colitis by compatible oral hydrogel microspheres with phages

Gut microbiota editing is a promising strategy for dysbiosis-related diseases. Here, the authors develop an oral phage delivery platform that enables precise microbiota editing, facilitates functional analysis of single species, and supports therapeutic intervention in dysbiosis.

Yufan Yang
Runze Li
Zhiyong Song
ResearchOpen Access06 Nov 2025
Nature Communications

Volume: 16, P: 1-18
Catalytic Joule heating synthesis of one-dimensional nanomaterials in seconds

A catalytic Joule heating approach is developed for the growth of one-dimensional nanomaterials via a vapour–liquid–solid mechanism under far-from-equilibrium reaction conditions. It demonstrates broad applicability for the rapid and energy-efficient synthesis of diverse nanowires and nanotubes, including refractory and high-entropy systems.

Jian Sheng
Yifan Xu
Yan Li
Research12 Nov 2025
Nature Synthesis

Volume: 5, P: 367-376
Evidence of water promotes cyclohexanol adsorption and dehydration over H-ZSM-5 zeolite

The role of water in the heterogeneous catalysis is a highly challenging topic. Here, the authors clarified the promotion of water on cyclohexanol (CyOH) adsorption and dehydration under a vapor phase condition.

Yaqi Hu
Runze Liu
Weili Dai
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-12
Senescent macrophages induce ferroptosis in skeletal muscle and accelerate osteoarthritis-related muscle atrophy

Xiang et al. use patient samples and mouse models of osteoarthritis to examine the link with muscle atrophy. They identify that, in osteoarthritis, senescent macrophages promote ferroptosis in skeletal muscle cells, and they show the therapeutic value of targeting this pathological mechanism.

Wei Xiang
Tongyi Zhang
Zhenhong Ni
ResearchOpen Access27 Jun 2025
Nature Aging

Volume: 5, P: 1295-1316
Large-scale quantum dot–lithium niobate hybrid integrated photonic circuits enabling on-chip quantum networking

Individual spectral strain tuning of waveguide-coupled quantum dot single-photon emitters into a thin-film lithium niobate photonic platform is demonstrated, allowing quantum interference of two spatially separated quantum dot single-photon emitters.

Xudong Wang
Xiuqi Zhang
Jiaxiang Zhang
Research04 Nov 2025
Nature Materials

Volume: 24, P: 1898-1905
Haplotype-resolved, gap-free genome assemblies provide insights into the divergence between Asian and European pears

Haplotype-resolved, gap-free genome assemblies for a representative Asian pear (Pyrus bretschneideri, ‘Dangshansuli’) and a European pear (Pyrus communis, ‘Max Red Bartlett’) provide insights into genome evolution and interspecies variation in Pyrus species.

Manyi Sun
Beibei Cao
Jun Wu
ResearchOpen Access06 Aug 2025
Nature Genetics

Volume: 57, P: 2040-2051
Biocatalytic, enantioenriched primary amination of tertiary C–H bonds

Direct stereoselective amination of tertiary C–H bonds without the assistance of directing groups is a challenging task in synthetic organic chemistry. Now a nitrene transferase is engineered to aminate tertiary C–H bonds with high enantioselectivity, providing direct access to valuable chiral α-tertiary primary amines.

Runze Mao
Shilong Gao
Frances H. Arnold
Research03 May 2024
Nature Catalysis

Volume: 7, P: 585-592
Harmonizing material quantity and terahertz wave interference shielding efficiency with metallic borophene nanosheets

High-performance THz electromagnetic shielding is demonstrated using 2D β₁₂-borophene nanosheets embedded in a polymer matrix. At a low loading of 0.1 wt.%, the composite has excellent shielding effectiveness and good mechanical properties.

Haojian Lin
Ximiao Wang
Fei Liu
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-11
Bruceine A protects nuclear receptor 4A1 from ubiquitin-degradation to alleviate mesangial proliferative glomerulonephritis

Huating Hu
Runze Li
Hudan Pan
ResearchOpen Access05 Dec 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-15
A programmable and self-adaptive ultrasonic wireless implant for personalized chronic pain management

An implantable ultrasound-induced wireless electrical stimulator and a machine learning-based pain classifier can generate programmable, closed-loop based self-adaptive electrical stimulation to the spinal cord to manage chronic pain.

Yushun Zeng
Chen Gong
Qifa Zhou
Research12 May 2025
Nature Electronics

Volume: 8, P: 437-449
Genome-wide association studies provide insights into the genetic determination of fruit traits of pear

Studies of fruit quality traits in pears are lagging behind the other major fruit trees. Here, the authors conduct GWAS of fruit quality and phenological traits in a panel of 312 sand pear accessions using SNPs called from resequencing data, and reveal the involvement of a lignin formation-related protein in regulating stone cell development.

Ming-Yue Zhang
Cheng Xue
Jun Wu
ResearchOpen Access18 Feb 2021
Nature Communications

Volume: 12, P: 1-10
NSUN2 mediated-aberrant 5-methylcytosine methylation regulates autophagy-related ferroptosis in oral squamous cell carcinoma progression

Yunyang Lu
Runze Li
Dongsheng Yu
ResearchOpen Access23 Dec 2025
Cell Death & Disease

Volume: 16, P: 1-15
Rule-based omics mining reveals antimicrobial macrocyclic peptides against drug-resistant clinical isolates

This study reports the genomics- and metabolomics-guided discovery of aminovinyl-(methyl-)cysteine-containing peptides (ACyP). One of these peptides, massatide A, demonstrates excellent activity against drug-resistant gram-positive pathogens.

Zhuo Cheng
Bei-Bei He
Yong-Xin Li
ResearchOpen Access08 Jun 2024
Nature Communications

Volume: 15, P: 1-13
Eliminating base-editor-induced genome-wide and transcriptome-wide off-target mutations

Wang et al. developed a transformer base editor system in which the enzyme activity of the base editor is turned on only at the on-target site, therefore minimizing genome-wide and transcriptome-wide off-target mutations.

Lijie Wang
Wei Xue
Jia Chen
Research10 May 2021
Nature Cell Biology

Volume: 23, P: 552-563
Wastewater sequencing reveals community and variant dynamics of the collective human virome

Tisza et al. carry out a sequencing-based analysis of wastewater samples from major cities, to detect and quantify hundreds of distinct pathogenic viruses, finding striking correlations between virus abundance and local clinical cases.

Michael Tisza
Sara Javornik Cregeen
Anthony W. Maresso
ResearchOpen Access28 Oct 2023
Nature Communications

Volume: 14, P: 1-10
Highly efficient prime editing by introducing same-sense mutations in pegRNA or stabilizing its structure

Prime editors can mediate all twelve types of base substitutions and small insertions or deletions in living cells but its efficiency remains low. Here the authors introduce same-sense mutations into pegRNAs to increase base-editing efficiency and the pegRNA secondary structure was altered to increase indel-editing efficiency.

Xiaosa Li
Lina Zhou
Jia Chen
ResearchOpen Access29 Mar 2022
Nature Communications

Volume: 13, P: 1-9
Biosynthesis of the nosiheptide indole side ring centers on a cryptic carrier protein NosJ

Thiopeptides such as nosiheptide are clinically-interesting antimicrobial natural products. Here the authors show the functional dissection of a series of enzymes involved in nosiheptide biosynthesis, revealing a unique biosynthetic pathway that centers on a previously-unknown carrier protein.

Wei Ding
Wenjuan Ji
Qi Zhang
ResearchOpen Access05 Sept 2017
Nature Communications

Volume: 8, P: 1-7
High-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effects

Several engineered Cas13 variants achieve targeted RNA degradation with minimal collateral effects.

Huawei Tong
Jia Huang
Hui Yang
Research11 Aug 2022
Nature Biotechnology

Volume: 41, P: 108-119
Auxiliary diagnostic method for children with autism spectrum disorder based on virtual reality and eye-tracking technology

Haoliang Chen
Xiaorui Zhang
Runze Liu
ResearchOpen Access18 Nov 2025
Scientific Reports

Volume: 15, P: 1-13
A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traits

A comprehensive map of genomic variation in melon derived from resequencing of 1,175 accessions sheds light on the population structure and domestication history of melon and agronomic traits for melon breeding.

Guangwei Zhao
Qun Lian
Sanwen Huang
Research01 Nov 2019
Nature Genetics

Volume: 51, P: 1607-1615
Genomic Portrait of Guangdong Liannan Yao Population Based on 15 Autosomal STRs and 19 Y-STRs

Yaoqi Liao
Ling Chen
Huilin Sun
ResearchOpen Access14 Feb 2019
Scientific Reports

Volume: 9, P: 1-6
High Reflectance Nanoscale V/Sc Multilayer for Soft X-ray Water Window Region

Qiushi Huang
Qiang Yi
Zhanshan Wang
ResearchOpen Access10 Oct 2017
Scientific Reports

Volume: 7, P: 1-7
A block mixture model to map eQTLs for gene clustering and networking

Ningtao Wang
Kirk Gosik
Rongling Wu
ResearchOpen Access19 Feb 2016
Scientific Reports

Volume: 6, P: 1-11
Analyzing the ecologicality and functionality of kiln architecture in China through KH coder data mining algorithm and hierarchical event coding

Runze Liu
Xiang Wang
Weicong Li
ResearchOpen Access09 May 2025
Scientific Reports

Volume: 15, P: 1-26
Evaluation and accurate diagnoses of pediatric diseases using artificial intelligence

A natural language processing system can support physicians in diagnostic assessments by extracting clinical information from electronic medical records to accurately predict diagnosis in pediatric patients.

Huiying Liang
Brian Y. Tsui
Huimin Xia
Research11 Feb 2019
Nature Medicine

Volume: 25, P: 433-438
Diverse virome and potential pathogens in five tick species from metropolis surroundings of Beijing and Tianjin, China

Wan‑Ying Gao
Xian Xia
Wu‑Chun Cao
ResearchOpen Access06 Dec 2025
npj Biofilms and Microbiomes

Volume: 12, P: 1-10
Research on multi-objective optimization design for high-precision turning-milling machine tool bed based on taguchi method -FEA

Wu Hongyi
Li Haozhen
Jianchen Wang
ResearchOpen Access26 Jul 2025
Scientific Reports

Volume: 15, P: 1-15
Spatial characteristics of soil potassium in the early stage of vegetation restoration and influencing factors in southwest China’s karst region

Yunjie Wu
Yujie Wu
Xin Tian
ResearchOpen Access15 Jan 2025
Scientific Reports

Volume: 15, P: 1-16
PPtase-activated production of borrelidin from extremophilic actinobacteria against multidrug-resistant cotton pathogen Verticillium dahliae

Fei Zhang
Xingzhi Jiao
Lei Li
Research05 Feb 2025
The Journal of Antibiotics

Volume: 78, P: 219-228
Changes in the annual cycle of surface air temperature over China in the 21st century simulated by CMIP6 models

Chenwei Zhang
Guocan Wu
Runze Zhao
ResearchOpen Access21 Apr 2025
Scientific Reports

Volume: 15, P: 1-16
Performance and perception: machine translation post-editing in Chinese-English news translation by novice translators

Yanxia Yang
Runze Liu
Jiayue Ni
ResearchOpen Access09 Nov 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-8
Author Correction: Homoharringtonine suppresses tumor proliferation and migration by regulating EphB4-mediated β-catenin loss in hepatocellular carcinoma

Man Zhu
Zhengyan Gong
Yanmin Zhang
Amendments and CorrectionsOpen Access02 Sept 2024
Cell Death & Disease

Volume: 15, P: 1-2
Nme8 is essential for protection against chemotherapy drug cisplatin-induced male reproductive toxicity in mice

Haixia Zhu
Hongxiang Wang
Jiangang Gao
ResearchOpen Access06 Oct 2024
Cell Death & Disease

Volume: 15, P: 1-12
Spatial mapping of cellular senescence: emerging challenges and opportunities

SenNet Consortium members review current and emerging methodologies for spatially resolved mapping of senescent cells. They discuss their limitations and challenges involved in the aim of creating a comprehensive atlas of senescent cells during aging.

Aditi U. Gurkar
Akos A. Gerencser
João F. Passos
Reviews03 Jul 2023
Nature Aging

Volume: 3, P: 776-790
Gss deficiency causes age-related fertility impairment via ROS-triggered ferroptosis in the testes of mice

Haixia Zhu
Yin Cheng
Bin Wu
ResearchOpen Access19 Dec 2023
Cell Death & Disease

Volume: 14, P: 1-14
Comparison of two surgical interventions for lumbar brucella spondylitis in adults: a retrospective analysis

Dingyu Jiang
Liang Ma
Yilu Zhang
ResearchOpen Access04 Oct 2023
Scientific Reports

Volume: 13, P: 1-9
CPEB3 deficiency in mice affect ovarian follicle development and causes premature ovarian insufficiency

Fang E.
He Zhang
Xu Gao
ResearchOpen Access20 Dec 2021
Cell Death & Disease

Volume: 13, P: 1-9
Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome

J. Yuyang Lu
Lei Chang
Xiaohua Shen
ResearchOpen Access29 Jan 2021
Cell Research

Volume: 31, P: 613-630
Central nervous system targeted autoimmunity causes regional atrophy: a 9.4T MRI study of the EAE mouse model of Multiple Sclerosis

A. Max Hamilton
Nils D. Forkert
Jeff F. Dunn
ResearchOpen Access11 Jun 2019
Scientific Reports

Volume: 9, P: 1-13
Homoharringtonine suppresses tumor proliferation and migration by regulating EphB4-mediated β-catenin loss in hepatocellular carcinoma

Man Zhu
Zhengyan Gong
Yanmin Zhang
ResearchOpen Access14 Aug 2020
Cell Death & Disease

Volume: 11, P: 1-13
Zika virus propagation and release in human fetal astrocytes can be suppressed by neutral sphingomyelinase-2 inhibitor GW4869

Yunlong Huang
Yuju Li
Jialin Zheng
ResearchOpen Access24 Apr 2018
Cell Discovery

Volume: 4, P: 1-16
Gene and mutation independent therapy via CRISPR-Cas9 mediated cellular reprogramming in rod photoreceptors

Jie Zhu
Chang Ming
Kang Zhang
CorrespondenceOpen Access21 Apr 2017
Cell Research

Volume: 27, P: 830-833

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