Nature Search

Revealing the role of interface disorder in modulating critical current density of Josephson junctions

Chuanbing Han
Huihui Sun
Zheng Shan
ResearchOpen Access06 Jan 2026
npj Computational Materials

P: 1-12
ARMH2 is a cytosolic component of CatSper crucial for sperm function

ARMH2 is identified as a previously unknown cytosolic component of the sperm-specific CatSper channel, critical for its normal assembly and pH/calcium sensitivity. Loss of ARMH2 impairs sperm hyperactivation and causes severe subfertility.

Qingqing Zhao
Shiyi Lin
Jianping Wu
ResearchOpen Access21 Nov 2025
Nature Communications

Volume: 16, P: 1-15
Tumour-associated macrophages serve as an acetate reservoir to drive hepatocellular carcinoma metastasis

Acetate accumulation and metastasis of hepatocarcinoma cells is driven by a metabolic interaction involving HCC-derived lactate and acetate secretion from tumour-associated macrophages.

Li Shen
Shenghao Wang
Ming Lu
Research20 Oct 2025
Nature Metabolism

Volume: 7, P: 2268-2283
Mitotic DNA repair by TMEJ suppresses replication stress-induced nuclear envelope reassembly defect

How replication stress affects nuclear integrity is not fully understood. Here, the authors report that replication stress induces DNA damage and nuclear envelope reassembly defect during mitosis, which is suppressed by DNA polymerase theta mediated end joining.

Guojun Ye
Yide He
Lin Deng
ResearchOpen Access03 Oct 2025
Nature Communications

Volume: 16, P: 1-18
Dual-scale chemical ordering for cryogenic properties in CoNiV-based alloys

Dual-scale chemical ordering in CoNiV-based alloys improves the synergy of strength and ductility at cryogenic temperatures, providing an approach for obtaining high-performance metallic materials for cryogenic applications.

Tiwen Lu
Binhan Sun
Shan-Tung Tu
ResearchOpen Access27 Aug 2025
Nature

Volume: 645, P: 385-391
The IRENA lncRNA converts chemotherapy-polarized tumor-suppressing macrophages to tumor-promoting phenotypes in breast cancer

Song and colleagues report that in breast cancer, chemotherapy induces the IRENA lncRNA, which reprograms tumor suppressive macrophages to protumorigenic phenotypes and promotes chemoresistance.

Jiang Liu
Liyan Lao
Erwei Song
Research12 Apr 2021
Nature Cancer

Volume: 2, P: 457-473
Bireociclib plus fulvestrant for HR+/HER2- advanced female breast cancer progressed on or after endocrine therapy: phase 3 BRIGHT-2 study interim analysis

While CDK4/6 inhibitors have become standard of care in patients with HR+/HER2- advanced breast cancer (ABC), selecting the optimal inhibitor could improve care further. Here, the authors report planned interim analysis of the BRIGHT-2 study, a randomised phase 3 trial comparing bireociclib (CDK4/6i) and fulvestrant (ET) against placebo and fulvestrant in female HR + /HER2- ABC patients.

Jiayu Wang
Qingyuan Zhang
Binghe Xu
ResearchOpen Access09 Apr 2025
Nature Communications

Volume: 16, P: 1-9
Crafting defects in two-dimensional organic platelets via seeded coassembly enables emergent molecular recognition

Defect engineering plays a pivotal role in materials science but achieving precise control over defects in pure organic systems remains a challenge. Here, the authors demonstrate the creation of controllable defects in molecular crystals through the supersaturated solution-fed seeded self-assembly of two strategically designed molecules.

Wenjun Tai
Lishan Sun
Jincai Zhao
ResearchOpen Access26 Aug 2025
Nature Communications

Volume: 16, P: 1-8
Conversion of methane to C₂ liquid oxygenates by Ru atom arrays

Atomic-level catalyst design faces challenges in methane activation and selective C–C coupling. Here, Ru atoms anchored on graphdiyne enhance methane oxidation, achieving high selectivity and yield for valuable C₂ liquid oxygenates.

Fanle Bu
Yurui Xue
Yuliang Li
ResearchOpen Access12 Aug 2025
Nature Communications

Volume: 16, P: 1-10
Reprogramming the myocardial infarction microenvironment with melanin-based composite nanomedicines in mice

Myocardial infarction (MI) is the most common emergent manifestation of cardiovascular diseases. Here, the authors designed a nanomedicine that can reprogram MI microenvironment by converting the detrimental substances (H+, ROS and hypoxia) into beneficial elements (O2 and H2O), as such demonstrates promising potential for the clinical application.

Yamei Liu
Shuya Wang
Yongping Bai
ResearchOpen Access06 Aug 2024
Nature Communications

Volume: 15, P: 1-14
Ammonia detoxification promotes CD8⁺ T cell memory development by urea and citrulline cycles

Ammonia detoxification is generally thought to occur exclusively in the liver. Here the authors show that ammonia detoxification via the urea and citrulline cycles is utilized by memory CD8⁺ T cells to maintain the longevity.

Ke Tang
Huafeng Zhang
Bo Huang
Research05 Dec 2022
Nature Immunology

Volume: 24, P: 162-173
HEARTSVG: a fast and accurate method for identifying spatially variable genes in large-scale spatial transcriptomics

The authors developed a computational method, HEARTSVG, which accurately identifies spatially variable genes in large-scale datasets, enhancing our understanding of tissue organization and disease mechanisms.

Xin Yuan
Yanran Ma
Zhangsheng Yu
ResearchOpen Access07 Jul 2024
Nature Communications

Volume: 15, P: 1-14
Detection of phosphates originating from Enceladus’s ocean

Cassini’s Cosmic Dust Analyzer mass spectra of ice grains emitted by Enceladus show the presence of sodium phosphates, suggesting that phosphorus is readily available in Enceladus’s ocean in the form of orthophosphates.

Frank Postberg
Yasuhito Sekine
Shuya Tan
ResearchOpen Access14 Jun 2023
Nature

Volume: 618, P: 489-493
High quantum efficiency of hydrogen production from methanol aqueous solution with PtCu–TiO₂ photocatalysts

Liquid water reforming of methanol is a promising method for on-demand hydrogen production. An atomic-level catalyst design strategy, using synergy between single atoms and nanodots, is now shown to demonstrate a high quantum efficiency for hydrogen production.

Hui Wang
Haifeng Qi
Junwang Tang
Research10 Apr 2023
Nature Materials

Volume: 22, P: 619-626
Automated thorax disease diagnosis using multi-branch residual attention network

Dongfang Li
Hua Huo
Shuya Chen
ResearchOpen Access24 May 2024
Scientific Reports

Volume: 14, P: 1-19
IGF2BP3 enhances lipid metabolism in cervical cancer by upregulating the expression of SCD

Chenying Han
Chenchen Hu
Shuya Yang
ResearchOpen Access14 Feb 2024
Cell Death & Disease

Volume: 15, P: 1-11
A comprehensive investigation of Glycoprotein-based nucleic acid vaccines for Hantaan Virus

Jiaxing Zhang
Junqi Zhang
Kun Yang
ResearchOpen Access23 Oct 2024
npj Vaccines

Volume: 9, P: 1-15
Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis

Pathological angiogenesis in the retina is a major cause of blindness. Here the authors show that adenosine receptor A2A drives pathological angiogenesis in the oxygen-induced retinopathy mouse model by promoting glycolysis in endothelial cells via the ERK/Akt/HIF-1α pathway, thereby suggesting new therapeutic targets for disease treatment.

Zhiping Liu
Siyuan Yan
Yuqing Huo
ResearchOpen Access19 Sept 2017
Nature Communications

Volume: 8, P: 1-18
Core N-DRC components play a crucial role in embryonic development and postnatal organ development

Chuan Ren
Shuya Sun
Mingxi Liu
ResearchOpen Access15 Mar 2025
Cell Death & Disease

Volume: 16, P: 1-14
Long-term trends of black carbon levels, sources, and radiative effects from 2013 to 2022 in Beijing, China

Yu Xie
Linghan Zeng
Min Hu
ResearchOpen Access01 May 2025
npj Clean Air

Volume: 1, P: 1-11
MLMD: a programming-free AI platform to predict and design materials

Jiaxuan Ma
Bin Cao
Sheng Sun
ResearchOpen Access21 Mar 2024
npj Computational Materials

Volume: 10, P: 1-12
Neoadjuvant pyrotinib and trastuzumab in HER2-positive breast cancer with no early response (NeoPaTHer): efficacy, safety and biomarker analysis of a prospective, multicentre, response-adapted study

Fei Wang
Yongjiu Wang
Zhigang Yu
ResearchOpen Access29 Jan 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-9
Blurred interface induced control of electrical transport properties in Josephson junctions

Junling Qiu
Huihui Sun
Zheng Shan
ResearchOpen Access27 Jul 2024
Scientific Reports

Volume: 14, P: 1-10
BCAP31, a cancer/testis antigen-like protein, can act as a probe for non-small-cell lung cancer metastasis

Jing Wang
Dongbo Jiang
Kun Yang
ResearchOpen Access04 Mar 2020
Scientific Reports

Volume: 10, P: 1-14
BAP31, a newly defined cancer/testis antigen, regulates proliferation, migration, and invasion to promote cervical cancer progression

Erle Dang
Shuya Yang
Kun Yang
ResearchOpen Access18 Jul 2018
Cell Death & Disease

Volume: 9, P: 1-15
O-terminated interface for thickness-insensitive transport properties of aluminum oxide Josephson junctions

Zheng Shan
Xuelian Gou
Lin Han
ResearchOpen Access12 Jul 2022
Scientific Reports

Volume: 12, P: 1-10
A general quantum algorithm for numerical integration

Guoqiang Shu
Zheng Shan
Shuya Wang
ResearchOpen Access07 May 2024
Scientific Reports

Volume: 14, P: 1-9
DHS (trans−4,4′-dihydroxystilbene) suppresses DNA replication and tumor growth by inhibiting RRM2 (ribonucleotide reductase regulatory subunit M2)

Chi-Wei Chen
Yongming Li
Wenge Zhu
Research05 Dec 2018
Oncogene

Volume: 38, P: 2364-2379
FMR1 promotes the progression of colorectal cancer cell by stabilizing EGFR mRNA in an m⁶A-dependent manner

Yuhan Hu
Qingzu Gao
Jiateng Zhong
ResearchOpen Access08 Nov 2022
Cell Death & Disease

Volume: 13, P: 1-14
Antibody-dependent-cellular-cytotoxicity-inducing antibodies significantly affect the post-exposure treatment of Ebola virus infection

Qiang Liu
Changfa Fan
Youchun Wang
ResearchOpen Access30 Mar 2017
Scientific Reports

Volume: 7, P: 1-11

Search

Revealing the role of interface disorder in modulating critical current density of Josephson junctions

ARMH2 is a cytosolic component of CatSper crucial for sperm function

Tumour-associated macrophages serve as an acetate reservoir to drive hepatocellular carcinoma metastasis

Mitotic DNA repair by TMEJ suppresses replication stress-induced nuclear envelope reassembly defect

Dual-scale chemical ordering for cryogenic properties in CoNiV-based alloys

The IRENA lncRNA converts chemotherapy-polarized tumor-suppressing macrophages to tumor-promoting phenotypes in breast cancer

Bireociclib plus fulvestrant for HR+/HER2- advanced female breast cancer progressed on or after endocrine therapy: phase 3 BRIGHT-2 study interim analysis

Crafting defects in two-dimensional organic platelets via seeded coassembly enables emergent molecular recognition

Conversion of methane to C₂ liquid oxygenates by Ru atom arrays

Reprogramming the myocardial infarction microenvironment with melanin-based composite nanomedicines in mice

Ammonia detoxification promotes CD8⁺ T cell memory development by urea and citrulline cycles

HEARTSVG: a fast and accurate method for identifying spatially variable genes in large-scale spatial transcriptomics

Detection of phosphates originating from Enceladus’s ocean

High quantum efficiency of hydrogen production from methanol aqueous solution with PtCu–TiO₂ photocatalysts

Automated thorax disease diagnosis using multi-branch residual attention network

IGF2BP3 enhances lipid metabolism in cervical cancer by upregulating the expression of SCD

A comprehensive investigation of Glycoprotein-based nucleic acid vaccines for Hantaan Virus

Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis

Core N-DRC components play a crucial role in embryonic development and postnatal organ development

Long-term trends of black carbon levels, sources, and radiative effects from 2013 to 2022 in Beijing, China

MLMD: a programming-free AI platform to predict and design materials

Neoadjuvant pyrotinib and trastuzumab in HER2-positive breast cancer with no early response (NeoPaTHer): efficacy, safety and biomarker analysis of a prospective, multicentre, response-adapted study

Blurred interface induced control of electrical transport properties in Josephson junctions

BCAP31, a cancer/testis antigen-like protein, can act as a probe for non-small-cell lung cancer metastasis

BAP31, a newly defined cancer/testis antigen, regulates proliferation, migration, and invasion to promote cervical cancer progression

O-terminated interface for thickness-insensitive transport properties of aluminum oxide Josephson junctions

A general quantum algorithm for numerical integration

DHS (trans−4,4′-dihydroxystilbene) suppresses DNA replication and tumor growth by inhibiting RRM2 (ribonucleotide reductase regulatory subunit M2)

FMR1 promotes the progression of colorectal cancer cell by stabilizing EGFR mRNA in an m⁶A-dependent manner

Antibody-dependent-cellular-cytotoxicity-inducing antibodies significantly affect the post-exposure treatment of Ebola virus infection

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