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A universal approach to construct low-resistance oxide layer by multiple tunnelling paths is proposed for efficient and durable Si-based photocathode. This approach can speed up the pace of development of practical photoelectrochemical devices.

Sclerostin impairs whole-body lipidandglucosemetabolism. Here, the authors further demonstrate that adipocytic sclerostin loop3-LRP4 interactionparticipatesin the impairment effect of sclerostin on whole-body lipid and glucose metabolism.

A pigeon-eye-inspired multimodal high-resolution tactile sensor, combined with a tactile language model, allows robots to achieve human-like tactile perception and understanding of their environment.

MsbA mediates the transport of lipopolysaccharide across the inner membrane. Here, the authors show specific MsbA-lipid interactions can tune the selectivity for binding ATP over ADP and present five structures of MsbA with one bound to lipid.

Here, the authors show that Lactobacillus acidophilus supplementation enhances oncolytic virus VSVΔ51 effect through restoring gut barrier integrity and microbiota homeostasis in mice.

The authors propose Analytic Fourier Ptychotomography, for analytically reconstructing aberration-free, complex-valued 3D refractive index distributions without iterative optimization or axial scanning. The method has potential applications in biology, microbial ecology, and clinical science.

HOXA2 expression was inhibited by aberrant hypermethylation, leading to decreased SIRT1 levels, which could increase ATF6 acetylation and activation as well as subsequent ER stress, resulting in renal damage in CKD-related fibrosis.

Detecting proton arrangements and quantum behavior at the atomic level is a challenge. Here, the authors use atomic force spectroscopy to reveal symmetry breaking in the proton arrangement in cyclic hydrogen bonds caused by nuclear quantum effects.

Angiogenesis-targeting secretome therapies may provide a new therapy for ischemic heart disease. Here, the authors show that CCL28 promotes angiogenesis via CCR10 signaling, and recombinant CCL28 offers therapeutic potential in ischemic models, including diabetic conditions.

Materials with opposite signs of permittivity along the two orthogonal directions can support hyperbolic polaritons. Here, the authors demonstrate tunable broadband near-infrared hyperbolic plasmon polaritons in MoOCl₂.

This study introduces an error-aware probabilistic update method (EaPU) that aligns stochastic analog compute-in-memory device behavior with neural network training dynamics, reducing weight updates and energy consumption.

A device for rectifying supercurrents at liquid-nitrogen temperature with high efficiency is demonstrated. This is a practical step towards implementing dissipationless electronics.

The study reports a metal-organic framework (MOF) - covalent organic framework (COF) nanocomposite with dual amine sites that captures CO₂ efficiently and remains stable under humid, harsh conditions, offering a promising path for next-generation carbon capture.

Cobalt ions in different sublayers of the double-layered Ruddlesden–Popper perovskite Sr₃Co₂O₇ are found to develop inequivalent ionic displacements, geometrically generating a polar state while preserving metallic conductivity and exhibiting antiferromagnetism.

Quantitative trait loci mapping has traditionally been used to discover desirable alleles in plants. In this study, Lyu et al. use a comparative genome approach to identify an allele that is prevalent in upland rice varieties and alters the function of a protein involved in abscisic acid biosynthesis.

Zheng et al. identify a role for CD160 in regulating CD8⁺ T cell exhaustion and cytotoxicity through the AKT–NF-κB pathway. The transfer of CD160⁺CD8⁺ T cells overcomes resistance to anti-PD-1 treatment in colorectal cancer models.

Two polypeptides synthesized by common bacterial strains in human gut microbiota lower body fat and blood glucose and increase bone density, improving the metabolism of rodents.

Efficient photocatalytic conversion of CO₂ into syngas is a promising but challenging technology. Here, the authors report a phase transformation method to produce Co sites with tunable electron localization on multi-dimensional architecture framework that can improve the syngas evolution kinetics.

Nitrogen promotes wheat’s recovery after drought stress through the TaSnRK2.10-TaNLP7 module. This breakthrough connects drought-stress signalling with nitrate response pathways, providing a genetic framework for developing climate-resilient crops.

Proteome profiling of plasma samples in human pan-cancer cohorts reveals patterns of biomarkers for diagnosis.

A 64-kb non-volatile digital compute-in-memory macro that is based on 40-nm spin-transfer torque magnetic random-access memory technology can achieve a software-equivalent inference accuracy for a residual network at 8-bit precision and physics-informed neural networks at 16-bit precision.

Catalysts enhance electrode reactions in static batteries but are inadequate for aqueous flow batteries. Here, authors develop carbon quantum dot catalytic electrolytes that function both in electrolyte and at-interface to improve reaction kinetics and low-temperature adaptability in Zn-Br systems.

Chromosome-scale genome assembly of a vegetable-type elite pea cultivar ZW1 and population analyses using resequencing data of 314 accessions provide insights into the genetic basis of Mendelian and other agronomic traits.

Neurons in the dorsal motor nucleus of vagus are involved in the absorption of fat in the intestine, and the natural compound puerarin shows utility in modulating this brain–gut axis to reduce fat absorption.

Comprehensive molecular characterisations could shed light on the high heterogeneity and poor prognosis of gliomas. Here, the authors perform proteomic profiling of 188 glioma patients, revealing immune and metabolic neuron-related subgroups as well as metabolic biomarkers linked to prognosis.

In this work Qiu et al. demonstrate that the application of van der Waals technology to STM/STS will dramatically expand the capabilities of the latter, allowing STM/STS to investigate the structure, electronic properties and magnetism of 2D magnetic insulators at the atomic scale.

Mesenchymal condensation is essential for cartilage development. Here, the authors report on a cell-adaptable supramolecular hydrogel to replicate the hypoxic environment and structural support needed for cartilage organoid formation and study the metabolic reprogramming involved.

The application of time-resolved photoemission electron microscopy (TR-PEEM) to non-conducting materials is challenging. Here, the authors report the TR-PEEM characterization of near-field dielectric modes and photoemission properties of insulating hexagonal boron nitride structures on indium tin oxide/glass substrates.

The authors demonstrate a zero-field supercurrent diode effect in NbSe₂/NiI₂/NbSe₂ vertical Josephson junctions, where NiI₂ is a two-dimensional multiferroic material. The diode efficiency is even as a function of field, making the device “resilient" to stray fields from nearby circuit components.

An industry-compatible disorder-to-disorder synthesis produces wafer-scale, ultraclean monolayer amorphous carbon in seconds that can be used as a membrane for generating high-precision proton beams.

The formation of directional fibrous tissue bands, typical of liver fibrosis progression, might be induced by the tension of the hepatic stellate cells, as studied with an in vitro microfabricated model.

The mechanisms by which tillandsioids adapt to elevated aerial habitats remain largely unexplored. Here, the authors report their evolution and link life history, diversification, comparative genomic, and functional changes to processes underlying the unique biology of air plants.

While Bell inequalities have been violated several times—mostly in photonic systems—their violations within particle physics experiments are less explored. Here, the BESIII Collaboration showcases Bell-violating nonlocal correlations between entangled hyperon pairs.