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Natural disasters induce power outages with unequal impacts on poverty and non-poverty counties in China. Climate change will further exacerbate this disparity.

Japonica subspecies has a lower nitrogen use efficiency (NUE) than that of indica rice. Here, the authors show that natural variations in the NIN-like protein 4 (OsNLP4) encoding gene are responsible for the divergence and introgression of the indica OsNLP4 allele into elite japonica cultivar can increase NUE and grain yield.

This study uses brain recordings, self-reports, and facial analysis to decode acute pain in epilepsy patients. Machine learning reveals stable neural markers in mesolimbic, striatal, and cortical regions, plus facial cues, enabling reliable pain detection in naturalistic settings.

How the brain supports speaking and listening during conversation of its natural form remains poorly understood. Here, by combining intracranial EEG recordings with Natural Language Processing, the authors show broadly distributed frontotemporal neural signals that encode context-dependent linguistic information during both speaking and listening..

Most kiwifruit species are vulnerable to high levels of heat stress. Here, the authors report natural variation at the GATA transcription factor binding site of EGY3 gene mediates chloroplastic ROS homeostasis to confer kiwifruit thermotolerance.

Vasomotor function is regulated by the autonomic nervous system, but its electrophysiological basis remains poorly captured, especially post-stenting. Here, the authors develop a bioadhesive bioelectronic interface for precise monitoring and modulation of vasomotor activity.

Padawer-Curry et al. show that the hallucinogenic 5-HT2A receptor agonist DOI alters neurovascular coupling in mice, with implications for the interpretation of human fMRI studies of psychedelics.

Recently there has been interest in using the orbital Hall effect to drive the magnetization of an adjacent ferromagnet. One metal, Tantalum, has been proposed a strong source of orbital current. Here, Liu and Zhu argue that the claimed orbital torques in Tantalum arise instead from self-induced spin-orbit torques in the adjacent ferromagnet.

Here the authors develop a novel statistical method for quantifying mutation burden from whole genome sequencing data and use it to discover the genetic, genomic, and phenotypic correlates of clonal hematopoiesis without known driver genetic lesions.

Long-range resonant quantum tunnelling of electrons happens across potential barriers when the wavefunction interferes constructively. Here, authors demonstrate an analogy in optical systems based on epsilon-near-zero materials, achieving long-range optical interactions beyond evanescent coupling.

Networks of miniaturized magnetoelectric wireless implantable devices can be individually powered and controlled by a single transmitter, show power and transfer data efficiencies that scale with the number of receivers and be used for spinal cord stimulation and cardiac pacing in large animals.

Cryo-electron microscopy structures of three large ornate natural bacterial RNA molecules reveal their quaternary structures and intra- and intermolecular interactions that stabilize them.

Nanolasers, valued for ultra-low power and nonlinearities, are promising for neuromorphic computing. Authors show coupled nanolaser arrays with symmetry-protected modes act as hidden nonlinear layers in photonic neural networks, enabling XNOR logic gates and highly compressed digit classification.

Peripheral nerve transfer can restore motor functions of the upper limbs after peripheral nerve injuries. Here, the authors developed an implantable multisite optogenetic stimulation system for wireless evaluation of peripheral nerve plexus with sub nerve resolution.

Hydrogen peroxide is a signaling molecule that can also cause damage if its levels are too high. Here, the authors report HyPerFLEX, a fluorescent sensor with tenable colors, to track very low peroxide levels in cellular organelles, even in low-oxygen or highly oxidizing environments.

Analyses of whole-genome sequencing data from UK Biobank and All of Us identify rare variant burden signals associated with metabolic health, including effects of protein-truncating variants in IRS2 on type 2 diabetes and chronic kidney disease risk.

Cortical networks switch from asynchronous firing to sudden synchronized population events. Here, the authors show that differential excitatory short-term synaptic plasticity onto either excitatory or inhibitory targets establishes and shapes the dynamics of these population events.

Radiative cooling is an emerging technology for cooling with reduced energy consumption. Here the authors present photoluminescent composites that combine subambient cooling with aesthetic colour, hydrophobicity and durability.

Probabilistic computing has emerged as a powerful route for tackling hard optimization. Here, authors show p-computers co-designed with modern hardware to run Monte Carlo algorithms solve hard optimization efficiently and establish a rigorous classical baseline to assess practical quantum advantage.

Across species, how aging leads to progressive spatial memory decline is not fully understood. This study reports dysfunctional spatial coding by aged entorhinal grid cells and networks related to impaired spatial memory and identifies implicated neuronal gene expression changes.

Neuroimmune interactions are important in amyotrophic lateral sclerosis (ALS). Here the authors characterize the role of NK cells in mouse models of ALS, and in patient tissue.

High-temperature, ultrathin, and high-performance microwave absorption is realized in the dual-layer structure with rare earth zirconate ceramics via electron delocalization-mediated thermionic migration and macroscopic interfacial resonance.

Potthoff and colleagues present a MALDI-MSI-based method that integrates in-source brightfield and fluorescence microscopy, which allows for spatially-resolved analysis of lipids and metabolites at the (sub)cellular level.

Here the authors perform a trans expression quantitative trait locus meta-analysis study of over 3,700 people and link a USP18 variant to expression of 50 inflammation genes and lupus risk, highlighting how genetic regulation of immune responses drives autoimmune disease and informs new therapies.

Prostate cancer (PCa) evaluation remains challenging due to its heterogenous and multifocal nature. Here, the authors reconstruct the nuclear chromatin compartmentalization of PCa patients-derived biopsies distinguishing two epigenetic subtypes and deriving an 18-gene signature with prognostic value on TCGA samples that is further validated with multiple independent PCa cohorts.

Spontaneous scrolling in two-dimensional polar van der Waals materials, driven by intrinsic out-of-plane electric polarization, enables the scalable production of nanoscrolls and their heterostructures.

The commercialization of perovskite solar cells has been impeded by lead toxicity and environmental leakage risks. Here, the authors incorporate a cellulose material into perovskite crystal to suppress lead leakage, achieving an optimal efficiency of 26.27% in environmentally stable devices.

Pseudocapacitors are emerging as alternatives to conventional supercapacitors. Here, authors showed an uncommon charge storage mechanism in a high-rate conjugated polyelectrolyte and demonstrated practical pouch and solid-state pseudocapacitor devices with competitive energy up to 71 μWh cm⁻² and power performance up to 160 mW cm⁻².

An optical slab waveguide with highly programmable nonlinear functionality is described, enabling the demonstration of versatile control over broadband second-harmonic generation across the spectral, spatial and spatio-spectral domains.

A full-featured 2D NOR flash memory chip realized by an atomic device to chip technology combines a superior 2D electronic device as a memory core and a powerful CMOS platform to support complex instruction control.

The authors significantly enhance the high-temperature energy storage performance of bismuth sodium titanate-based relaxor ferroelectric multilayer ceramic capacitors via entropy modulated strain heterogeneity.

A new version of nanorate DNA sequencing, with an error rate lower than five errors per billion base pairs and compatible with whole-exome and targeted capture, enables epidemiological-scale studies of somatic mutation and selection and the generation of high-resolution selection maps across coding and non-coding sites for many genes.

A coherent 909-Hz quasi-periodic oscillation was potentially detected in GRB 230307A, the second brightest gamma-ray burst to date, indicating that a millisecond magnetar formed after the merger powered the burst.

Ultrafast SERS combined with nanopore sequencing allows distinguishing similar nucleotides at the single-molecule level, offering a step towards molecular sequencing with the aid of machine learning.

National parochialism is the tendency to cooperate more with people of the same nation. In a 42-nations study, the authors show that national parochialism is a pervasive phenomenon, present to a similar degree across all the studied nations, and occurs both when decisions are private or public.

Here, Ni-anchored Ru/RuO₂ heterostructure nanosheets serve as CO-tolerant hydrogen oxidation catalyst delivering a peak power density of 1.76 W cm^-2, along with long-term stability in an alkaline exchange membrane fuel cell operating under H₂/Air conditions.

High-resolution ALMA observations reveal a gravitationally bound septuple protostar system in NGC 6334IN, formed through disk fragmentation. This discovery sheds light on the formation of extreme high-order multiplicity in massive stellar clusters.

This study reports on a closed-loop approach combining multiscale simulations, interpretable machine learning, experiments and techno-economic analysis for systematic plasma catalyst design, showing that alloys from noncritical minerals can potentially replace costly noble metals such as ruthenium for hydrogen production from ammonia decomposition under plasma conditions.

Whole-exome sequencing analyses in a cohort of 2,140 participants with female infertility after recurrent in vitro fertilization, coupled with functional analyses, identified genes associated with oocyte and early embryo competence defects.

This prospective cohort study of patients with cancer incorporated antemortem follow-up visits and rapid autopsy analyses, and reports that spikes—rapidly increasing levels—of circulating tumor cell clusters, observed immediately before and at the time of death, along with tumor masses infiltrating large vessels, were cancer-related events associated with patient mortality.

Khawaja et al. show sex-specific differences in neuronal-activity regulation by chaperone-mediated autophagy and that loss of chaperone-mediated autophagy leads to defective neuronal physiology and increased seizure susceptibility, linking chaperone-mediated autophagy to neuronal excitability.

Achieving room-temperature blackbody-sensitive photodetectors with an ultrabroadband response is challenging. Here, the authors report a bioinspired detector using the 2D flat-band quantum material Nb3I8 that enables sensitive detection from the shortwave to the very long-wave infrared.

The magnetoelastic coupling at a ferroelectric-ferromagnetic interface is shown to be dominated by shear-strain effects. Using polarised x-ray microscopy to simultaneously image the ferroic domain structures, the authors demonstrate an anomalous coupling in the ultrathin film limit.

Computational models can help to explain the dynamics of cellular infection with pathogens. Here the authors use computational models to assess the single cell infection parameters of human macrophage infection with Legionella pneumophila and the effects on immunometabolism at a single cell and population level.

Young adults face rising loneliness and mental health challenges. In a study of 5,192 undergraduates, Pei et al. find that perceiving peers as empathic is related to better well-being. Students, however, underestimate peers’ empathy. Two field experiments offered simple interventions that reduced this empathy perception gap and increased social behaviour and connection.

Ying and colleagues present PhyE2E, an AI framework incorporating symbolic search techniques for discovering physics formulas directly from data. The method has already led to improvements in space physics models when compared, for example, with NASA’s 1993 formula for solar activity.

Young and colleagues describe an atmospheric pressure transmission-geometry MALDI approach equipped with plasma ionisation, which allows for subcellular mass spectrometry imaging of lipids and nucleotides in cells and tissues.

The electronic ground state of a correlated oxide interface is reversibly switched by light. Stemming from interfacial reconstructions, electrostatic confinement and photodoping, this effect opens a path towards engineering the optical response of oxides.

HippoMaps provides an open-source resource for studying the human hippocampus at different scales and with different modalities such as histology, fMRI, structural MRI and EEG.