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Showing 51–100 of 102 results

Advanced filters: Author: Haibo Lu Clear advanced filters

Development of a reverse transcription loop mediated isothermal amplification assay for the detection of Mouse reovirus type 3 in laboratory mice

Taofeng Lu
Lingyun Tao
Jie Zhou
ResearchOpen Access10 Feb 2021
Scientific Reports

Volume: 11, P: 1-9
Severe lymphopenia as a prognostic factor in rectal cancer patients receiving adjuvant chemoradiotherapy: a retrospective study

Shuang Li
Weiping Yao
Xiaodong Liang
ResearchOpen Access09 May 2023
Scientific Reports

Volume: 13, P: 1-9
A reciprocal regulatory loop between TAZ/YAP and G-protein Gαs regulates Schwann cell proliferation and myelination

The Hippo pathway has recently been implicated in Schwann cell (SC) development and myelination. Here the authors reveal mechanistic insights into how TAZ and YAP regulate and interact with target genes; they further identify a negative feedback loop between TAZ/YAP and G protein Gαs that balances SC proliferation and differentiation.

Yaqi Deng
Lai Man Natalie Wu
Q. Richard Lu
ResearchOpen Access26 Apr 2017
Nature Communications

Volume: 8, P: 1-15
HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination

Using genetic approaches, this study shows that HDAC1 and HDAC2 acetylation of NF-κB is required for proper Schwann cell myelination in the peripheral nervous system and for Schwann cell differentiation.

Ying Chen
Haibo Wang
Q Richard Lu
Research20 Mar 2011
Nature Neuroscience

Volume: 14, P: 437-441
Regulation of PERK–eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes

The molecular mechanisms regulating myelination are only partially understood. Here authors show that Tsc1ablation in oligodendrocyte lineage activates ER stress and apoptotic programs in mice, and that enhancing PERK-eIF2α signalling partially rescues the myelination defects in Tsc1 mutants.

Minqing Jiang
Lei Liu
Q. Richard Lu
ResearchOpen Access15 Jul 2016
Nature Communications

Volume: 7, P: 1-15
Vegetation feedback causes delayed ecosystem response to East Asian Summer Monsoon Rainfall during the Holocene

How the East Asian Summer Monsoon has changed over the Holocene has been debated, as some proxy records disagree with each other. Here, the authors suggest that monsoonal rainfall peaked in the early Holocene, while ecosystem responses peaked in the mid-Holocene, explaining the differences between records.

Jun Cheng
Haibin Wu
Yaoming Song
ResearchOpen Access23 Mar 2021
Nature Communications

Volume: 12, P: 1-9
The metabolic hormone leptin promotes the function of T_FH cells and supports vaccine responses

T follicular helper (TFH) cell numbers are increased after vaccination and fewer of these cells might result in reduced vaccine responses. Here the authors show in mice and humans that leptin promotes T_FH differentiation and that low leptin levels can impair T_FH response to vaccines and virus protection in mice.

Jun Deng
Qian Chen
Di Yu
ResearchOpen Access24 May 2021
Nature Communications

Volume: 12, P: 1-15
A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese

Hongbing Shen and colleagues report a genome-wide association study for lung cancer in individuals of Han Chinese ancestry. The authors identify two new lung cancer susceptibility loci.

Zhibin Hu
Chen Wu
Hongbing Shen
Research03 Jul 2011
Nature Genetics

Volume: 43, P: 792-796
Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination

In this study, He et al. find that the CHARGE syndrome–related chromatin remodeler Chd7 regulates the initiation of myelination and remyelination in the CNS. Chd7 interacts with Sox10 to orchestrate the transcriptional state of myelinogenic genes and serves as a molecular nexus of the regulatory networks that contribute to white matter pathogenesis in CHARGE syndrome.

Danyang He
Corentine Marie
Q Richard Lu
Research29 Feb 2016
Nature Neuroscience

Volume: 19, P: 678-689
Zeb2 recruits HDAC–NuRD to inhibit Notch and controls Schwann cell differentiation and remyelination

This study shows that the transcriptional regulator Zeb2 is required for the onset of peripheral myelination and remyelination. Zeb2 recruits HDAC1–HDAC2–NuRD co-repressor complexes to antagonize inhibitory effectors including Notch, while activating promyelinogenic factors. A Mowat-Wilson syndrome–associated ZEB2 mutation disrupting HDAC–NuRD interaction abolishes Zeb2 activity for Schwann cell differentiation.

Lai Man Natalie Wu
Jincheng Wang
Q Richard Lu
Research01 Aug 2016
Nature Neuroscience

Volume: 19, P: 1060-1072
Induced effects of advanced oxidation processes

Peng Liu
Chaolin Li
Wenfang Zhang
ResearchOpen Access07 Feb 2014
Scientific Reports

Volume: 4, P: 1-4
Tetranectin as a Potential Biomarker for Stable Coronary Artery Disease

Yanjia Chen
Hui Han
Wei Jin
ResearchOpen Access01 Dec 2015
Scientific Reports

Volume: 5, P: 1-8
Genetic and functional analysis of a Li Fraumeni syndrome family in China

Huaying Hu
Jingping Liu
Jia-Da Li
ResearchOpen Access28 Jan 2016
Scientific Reports

Volume: 6, P: 1-8
Depletion of oxysterol-binding proteins by OSW-1 triggers RIP1/RIP3-independent necroptosis and sensitization to cancer immunotherapy

Xinyan Lu
Dongshi Chen
Lin Zhang
ResearchOpen Access06 May 2025
Cell Death & Differentiation

P: 1-15
An EEG dataset for interictal epileptiform discharge with spatial distribution information

Nan Lin
Mengxuan Zheng
Qiang Lu
ResearchOpen Access07 Feb 2025
Scientific Data

Volume: 12, P: 1-8
Flexible PVDF membranes with exceptional robust superwetting surface for continuous separation of oil/water emulsions

Zhu Xiong
Haibo Lin
Dehong Li
ResearchOpen Access26 Oct 2017
Scientific Reports

Volume: 7, P: 1-12
A single-cell transcriptomic landscape of the lungs of patients with COVID-19

Wang et al. analysed post-mortem samples of the lungs of patients with COVID-19 by bulk and single-nucleus RNA sequencing along with proteomics and discovered lung senescence as a feature of COVID-19 pathology.

Si Wang
Xiaohong Yao
Xiu-Wu Bian
Research07 Dec 2021
Nature Cell Biology

Volume: 23, P: 1314-1328
N6-Methyladenosine-modified circSAV1 triggers ferroptosis in COPD through recruiting YTHDF1 to facilitate the translation of IREB2

Haibo Xia
Yan Wu
Qizhan Liu
Research24 Feb 2023
Cell Death & Differentiation

Volume: 30, P: 1293-1304
Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population

Hongbing Shen and colleagues identify three new susceptibility loci for lung cancer in the Chinese population. Their follow-up analyses suggest that two of these loci interact multiplicatively with smoking dose to influence lung cancer risk.

Jing Dong
Zhibin Hu
Hongbing Shen
Research15 Jul 2012
Nature Genetics

Volume: 44, P: 895-899
PDZK1 confers sensitivity to sunitinib in clear cell renal cell carcinoma by suppressing the PDGFR-β pathway

Haibo Wang
Lijie Zhang
Junqi He
Research31 May 2024
British Journal of Cancer

Volume: 131, P: 347-360
Quantitative Phosphoproteomic Analysis Reveals Key Mechanisms of Cellular Proliferation in Liver Cancer Cells

Bo Zhu
Quanze He
Wenbo Yu
ResearchOpen Access07 Sept 2017
Scientific Reports

Volume: 7, P: 1-12
In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR–dCas9-activator transgenic mice

dCas9-mediated activation has been verified and widely used in vitro. Here the authors generated a potent in vivo activation platform and applied it to control the transcription of multiple genetic elements in the mammalian brain.

Haibo Zhou
Junlai Liu
Hui Yang
Research15 Jan 2018
Nature Neuroscience

Volume: 21, P: 440-446
Cilia-driven cerebrospinal fluid flow directs expression of urotensin neuropeptides to straighten the vertebrate body axis

In zebrafish, cilia-driven flow of cerebrospinal fluid transports adrenergic signals that induce urotensin neuropeptides in spinal cord neurons. In turn, these neuropeptides activate their receptor on nearby muscle fibers, straightening the body axis.

Xiaoli Zhang
Shuo Jia
Chengtian Zhao
Research12 Nov 2018
Nature Genetics

Volume: 50, P: 1666-1673
Study on mechanical properties of sandstone damaged by blasting load under triaxial cyclic loading and unloading

Haibo Wang
Genshuo Zhu
Hao Wang
ResearchOpen Access03 Jan 2025
Scientific Reports

Volume: 15, P: 1-14
Prognostic signature and therapeutic drug identification for dilated cardiomyopathy based on necroptosis via bioinformatics and experimental validation

Han Yang
Zhenwei Wang
Yang Lu
ResearchOpen Access02 Jan 2025
Scientific Reports

Volume: 15, P: 1-15
LMO2 promotes the development of AML through interaction with transcription co-regulator LDB1

Lihui Lu
Jianwei Wang
Hailong He
ResearchOpen Access12 Aug 2023
Cell Death & Disease

Volume: 14, P: 1-15
Prophylactic donor-derived CD19 CAR-T cell infusion for preventing relapse in high-risk B-ALL after allogeneic hematopoietic stem cell transplantation

Wenyi Lu
Hairong Lyu
Mingfeng Zhao
ResearchOpen Access17 Apr 2024
Leukemia

Volume: 38, P: 1419-1422
IL-1β promotes glutamate excitotoxicity: indications for the link between inflammatory and synaptic vesicle cycle in Ménière’s disease

Na Zhang
Yongdong Song
Na Li
ResearchOpen Access20 Nov 2024
Cell Death Discovery

Volume: 10, P: 1-11
A dysbiotic microbiome promotes head and neck squamous cell carcinoma

Daniel N. Frank
Yue Qiu
Shi-Long Lu
Research28 Jan 2022
Oncogene

Volume: 41, P: 1269-1280
Impact of first-line antihypertensive drug class and intensity on NT-proBNP improvement and cardiovascular outcomes among hypertensive patients with pre-heart failure: findings from SPRINT trial

Association between antihypertensive drug classes and intensity with NT-proBNP improvement and long-term clinical outcome.

Lili Wang
Jiayi Yi
Xin Zheng
Research02 Oct 2024
Hypertension Research

Volume: 47, P: 3447-3457
Experimental study on mechanical properties and breakage of high temperature carbon fiber-bar reinforced concrete under impact load

Hao Wang
Nao Lv
Qi Zong
ResearchOpen Access04 Sept 2024
Scientific Reports

Volume: 14, P: 1-15
Elevated Kir2.1/nuclear N2ICD defines a highly malignant subtype of non-WNT/SHH medulloblastomas

Yan-Xia Wang
Haibo Wu
Xiu-Wu Bian
ResearchOpen Access11 Mar 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-15
AC010973.2 promotes cell proliferation and is one of six stemness-related genes that predict overall survival of renal clear cell carcinoma

Yingqing Liu
Jiawei Wang
Xinglin Chen
ResearchOpen Access11 Mar 2022
Scientific Reports

Volume: 12, P: 1-11
Size effect on the deformation mechanisms of nanocrystalline platinum thin films

Xinyu Shu
Deli Kong
Yinong Liu
ResearchOpen Access16 Oct 2017
Scientific Reports

Volume: 7, P: 1-11
Multi-platform omics analysis reveals molecular signature for COVID-19 pathogenesis, prognosis and drug target discovery

Yuming Li
Guixue Hou
Yonghao Xu
ResearchOpen Access15 Apr 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-11
Folate Metabolism Regulates Oligodendrocyte Survival and Differentiation by Modulating AMPKα Activity

Qinjie Weng
Jiajia Wang
Qiaojun He
ResearchOpen Access11 May 2017
Scientific Reports

Volume: 7, P: 1-13
Experimental study on fractal dimension of energy dissipation and crack growth in saturated tuff at different strain rates

Hao Wang
Qi Zong
Haibo Wang
ResearchOpen Access10 Jun 2024
Scientific Reports

Volume: 14, P: 1-15
Legal issues in automated vehicles: critically considering the potential role of consent and interactive digital interfaces

Jo-Ann Pattinson
Haibo Chen
Subhajit Basu
ResearchOpen Access18 Nov 2020
Humanities and Social Sciences Communications

Volume: 7, P: 1-10
Neuron-specific enolase promotes stem cell-like characteristics of small-cell lung cancer by downregulating NBL1 and activating the BMP2/Smad/ID1 pathway

Lin Lu
Zhiqiang Zha
Guolong Liu
ResearchOpen Access29 Apr 2022
Oncogenesis

Volume: 11, P: 1-14
Beta diversity determinants in Badagongshan, a subtropical forest in central China

Xiujuan Qiao
Qianxi Li
Mingxi Jiang
ResearchOpen Access23 Nov 2015
Scientific Reports

Volume: 5, P: 1-9
CNV profiles of Chinese pediatric patients with developmental disorders

Haiming Yuan
Shaofang Shangguan
Xiaoli Chen
Research05 Jan 2021
Genetics in Medicine

Volume: 23, P: 669-678
Patient-derived SARS-CoV-2 mutations impact viral replication dynamics and infectivity in vitro and with clinical implications in vivo

Hangping Yao
Xiangyun Lu
Lanjuan Li
ResearchOpen Access29 Oct 2020
Cell Discovery

Volume: 6, P: 1-16
Genome-wide association study using whole-genome sequencing identifies risk loci for Parkinson’s disease in Chinese population

Hongxu Pan
Zhenhua Liu
Beisha Tang
ResearchOpen Access09 Feb 2023
npj Parkinson's Disease

Volume: 9, P: 1-11
Engineered mitochondria in diseases: mechanisms, strategies, and applications

Mingyang Li
Limin Wu
Bin Shen
ReviewsOpen Access03 Mar 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-34
ILDR1 promotes influenza A virus replication through binding to PLSCR1

Yueyue Liu
Shuqian Lin
Jiaqiang Wu
ResearchOpen Access20 May 2022
Scientific Reports

Volume: 12, P: 1-13
Experimental throughfall reduction barely affects soil carbon dynamics in a warm-temperate oak forest, central China

Haibo Lu
Shirong Liu
Yi Wang
ResearchOpen Access08 Nov 2017
Scientific Reports

Volume: 7, P: 1-10
Genetic and molecular characterization of H9N2 and H5 avian influenza viruses from live poultry markets in Zhejiang Province, eastern China

Haibo Wu
Xiuming Peng
Nanping Wu
ResearchOpen Access02 Dec 2015
Scientific Reports

Volume: 5, P: 1-12
Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer’s Disease via Fusion of Clinical, Imaging and Omic Features

Asha Singanamalli
Haibo Wang
Kristin Fargher
ResearchOpen Access15 Aug 2017
Scientific Reports

Volume: 7, P: 1-14
The Tie2-agonist Vasculotide rescues mice from influenza virus infection

Michael G. Sugiyama
Susan M. Armstrong
Warren L. Lee
ResearchOpen Access05 Jun 2015
Scientific Reports

Volume: 5, P: 1-10
Exome sequencing identifies a novel CEACAM16 mutation associated with autosomal dominant nonsyndromic hearing loss DFNA4B in a Chinese family

Honghan Wang
Xinwei Wang
Yong Feng
Research15 Jan 2015
Journal of Human Genetics

Volume: 60, P: 119-126

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