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Experimental evidence demonstrates long-distance remote epitaxial interactions of thin films even through thick amorphous carbon buffer layers and shows that these can be induced through dislocations in the substrate.

Poor mechanical stability under high humidity remains a critical challenge for flexible perovskite solar cells. Here, the authors develop a bioinspired dopamine containing polymer to enhance adhesion in humid environments, achieving an efficiency of nearly 26%.

In the dose-expansion cohort of this phase 1b trial, the EGFR×HER3 bispecific antibody–drug conjugate BL-B01D1 given to patients with metastatic esophageal squamous cell carcinoma led to encouraging clinical response rates, which need to be confirmed in larger efficacy trials.

The authors demonstrate standing ceramic circuit boards (S-CCBs) with high-resolution and high aspect-ratio fabricated via sacrificial coating-assisted micro-3D printing, which have both high-density integration and large current-carrying capacity

Jin, Du et al. develop a proteomic-based aging clock, called ProteAge, designed to estimate biological age and predict mortality risk using proteomics data from the UK Biobank. Findings reveal clear sex-specific differences in aging trajectories with women showing more complex, nonlinear patterns, whereas men tend to age in a more linear fashion.

Wafer-scale 3R-MoS₂ with high phase purity is achieved through a homoepitaxy strategy, which demonstrates ferroelectricity and holds promise for multifunctional integration.

Zheng et al. identify a non-canonical RNA polymerase II kinase, CDKL9, that tends to act when plants are under heat stress. Acetylated-histone-binding proteins GTE2 and GTE7 help CDKL9 localize to targets. All of these proteins are important for plant heat tolerance.

SFTS is an emerging tick-borne disease with high mortality rates caused by the SFTS virus. Here, the authors identify LRP1 as an entry factor for SFTSV, show that SFTSV glycoprotein Gn interacts with LRP1 and that blocking LRP1 reduces viral infection and improves survival in lethal mouse models.

The low adhesive fracture energy of electron transport layer/perovskite interface makes it prone to delamination under mechanical stress. Here, authors develop polyamide-amine-based hyperbranched polymer to provide strong adhesion, leading to device efficiency of over 25% for perovskite solar cells.

Microbial nitrogen cycling on Tibetan Plateau glacier surfaces remains poorly understood. This study reveals over 90% taxa possess nitrogen metabolic potential (33% transcriptionally active), with temperature-nitrogen co-regulation identified.

Substrate specificity of ECF transporters is determined by the transmembrane EcfS protein subunit. Here Zhao et al.present substrate-bound and substrate-released structures of a bacterial folate transporter EcfS and suggest a gating mechanism for ECF transporters.

Targeted degradation has the potential to treat diseases associated with pathological protein build up. Here, the authors report on an oligo-PROTAC which degrades FUS, a protein associated with frontotemporal dementia, demonstrating delivery on DNA nanoflowers for increase blood-brain barrier crossing and retention.

Ferroelectric field-effect transistors based on molybdenum disulfide can be used to build an in-memory sparsity architecture in which index memory is moved next to individual synapses, creating a sparse neural network without external memory indexing.

Digital polymers with precisely ordered units for next-generation data storage media are continually investigated for higher storage capacity. Here the authors show the synthesis of information-coded 2D digital dendrimers and the generated data matrix barcode can be read by a common hand-held device.

Isopropyl alcohol can play a significant role in anti-virus diagnosis but generally yields limited response in conventional detection. Here, authors propose a methodology of AI-enhanced ion mobility and mid-infrared spectroscopy for accurate gas identification despite presence different carbon-based gases.

The development of hole-selective contacts for Sn-based perovskite solar cells is highly desirable. Here, the authors report self-assembled monolayers with oligoether side chains on the benzothiadiazole unit and achieve an efficiency of 28.61% for operationally stable all-perovskite tandems.

The evolutionary reasons for the variation in silicon concentrations across plant families remain unclear. This paper provides new evidence that silicon variation is closely linked to global and long-term climate change, suggesting temperature could have driven the evolution of plant silicification.

Workers in social insects such as honey bees, bumble bees, and ants are expected to spend their lives helping their mother reproduce. Here the authors show that workers of several bumble bee species can in fact mate and lead colonies of their own.

Voice communication faces challenges from noise and obstructions. Here, the authors present a flexible PMUT-based wearable sensor, focusing on signal capture, noise resistance, and applications in HMI, IoT, and speech disorder assistance.

The discovery of the resistosome was a milestone in plant immunity. Here, Zhong et al. identify a kinase that phosphorylates the NLR, and reveal how this kinase regulates resistosome assembly to fine-tune immune responses.

The altermagnet candidate RuO₂ has sparked recent debate in the scientific community regarding its magnetic ground state and the existence of a crystal Hall effect. Here, the authors synthesize high-quality RuO₂ crystals and provide comprehensive measurements to reveal that its magneto-transport properties obey scaling law and align with a non-magnetic semimetal model, challenging the notion of RuO₂ as an altermagnet and refining our understanding of its electronic structure.

Healthy and sustainable diets that better match the dietary preferences and economic affordability of specific groups are needed to achieve the Sustainable Development Goals. To address this gap, this study proposes a region-specific reference diet for China and compares it to global dietary guidelines.

TP63 is a master regulator transcription factor in squamous cell carcinomas (SCCs). Here the authors report that TP63 suppresses IFNγ signaling in SCC tumors and that its inhibition is associated with enhanced anti-tumor immunity and response to anti-PD1.

Ion-conductive materials have received much attention because of their good mechanical and electrical properties, though practically they are hampered by limited toughness and crack-resistance. Here, the authors report a fiber reinforced composite ionogels to efficiently dissipate energy for a tough crack-resistant conductive gel.

The authors resequence a core collection of upland cotton (Gossypium hirsutum) comprising 419 accessions. They analyze genomic variation and conduct a genome-wide association study for 13 fiber quality and yield traits in 12 different environments.

The search for low-dimensional condensed matter platforms that host correlated electronic states has recently revolved around kagome lattices. Here, the authors evidence kagome-like bands in a 2D coloring-triangle lattice with a semiconducting bandgap.

By integrating split ferroelectric capacitors with complementary characteristics in the same memory cell, this architecture tackles the problem of conflicting memory requirements for training and inference, which has long plagued edge intelligence applications.

Chromosome-scale genome assemblies of triploid Cavendish and Gros Michel reveal the banana cultivars’ origins, disease resistance and fruit ripening mechanism.

The authors demonstrate a chemopiezoelectric effect in which the displacive migration of oxygen vacancies driven by an electric field induces a large strain in the surface layer of thin (K,Na)NbO₃ ceramics. They achieve an electrostrain of 1.9% under a field of −3 kV mm⁻¹, with thermal stability up to 200 °C.

Genomic analyses of Citrus species including haplotype-resolved genomes of Citrus sinensis and Citrus aurantium highlight the origin of sweet orange and provide a strategy for de novo domestication of perennial crops.

Introduction of any interface will inevitably lead to a decrease in carrier mobility. Here, authors employ atomic layer deposition technology to construct composite phase interfaces, decoupling the interrelated thermoelectric parameters in n-type ZrNiSn materials.

Although traditionally considered an obstacle to the study of quantum effects, dissipation has now been shown to enable the measurement of strong quantum fluctuations in one-dimensional atomic gases.

In the largest study so far of CAR T cells in patients with solid tumors, autologous CLDN18.2-targeting CAR T cell therapy was well tolerated in patients with advanced CLDN18.2-positive gastrointestinal cancers, with an overall response rate of 42.2% and a disease control rate of 91.1%.

Coordinating protein translation with energy supply is a significant challenge faced by cells. Here, the authors found that the protein quality control network may provide a link between the two.

A monolithically integrated near-infrared imager is achieved with the crystallization- and oxidation-modulated tin-lead perovskites.

Superluminous supernova SN 2017egm has a complex light curve that is well modelled by successive collisions of a shockwave with dense circumstellar shells ejected by its massive progenitor star during the pair-instability pulsation stage. Such a scenario might be responsible for providing a power source for superluminous supernovae in general.

Current methods to identify and phenotype human enteroviruses (HEV) have limitations. Here, the authors report a sequence-specific nanoparticle barcode method for simultaneous detection of 10 HEV types with enhanced sensitivity and specificity as a promising tool for improved clinical and epidemiological applications.