Cardiovascular Medicine and Haematology articles

Time frame: 1 July 2025 - 30 June 2026

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Count: 1726

Article ‘Count’ for Cardiovascular Medicine and Haematology.

Journal Count
20
Force-Induced Ankle Opening Reveals Mechanical Stabilization of the Ankle of Human β-Cardiac Myosin
Intravascular Ultrasound-Guided Local Theranostics Enables Precise Treatment of Atherosclerotic Plaques
A Lung-Targeted Carrier of Carbon Monoxide for Idiopathic Pulmonary Fibrosis Therapy
Lung-Accumulating Mucin 5AC Silencing by Noninflammatory Lipid Nanoparticles for Asthma Treatment
Reprogramming Lesional Macrophage Homeostasis via Interferon Regulatory Factor 5 Targeted siRNA Nanoimmunotherapy for Atherosclerosis
Biomimetic Selenium-Encrusted Prussian Blue Nanozyme for Myocardial Infarction by Coordinated Enhancement of Mitophagy and Reactive Oxygen Species Scavenging
Engineering T Cells with Membrane-Anchored Nitric Oxide Scavengers for Anticancer Therapy
D-Mannose-Modified M2 Macrophage Membrane-Derived Decoy Nanovesicles for Synergistic Immunotherapy of Asthma
In Situ Reprogramming of Senescent Microenvironment via Augmentation of Endogenous Senolytic Actions for Advanced Atherosclerosis Management
In Vivo Immunomodulatory Programming of Circulating Myeloid Cells via Itaconic Acid Liposomes to Mitigate Myocarditis
Biomimetic Macrophages Inhibit Atherosclerosis in ApoE–/– Mice through Inducing Macrophages Autophagy
Toward a ToxAtlas of Carbon-Based Nanomaterials: Single-Cell RNA Sequencing Reveals Initiating Cell Circuits in Pulmonary Inflammation
Inhalation of Mesenchymal-Stem-Cell-Derived Nanovesicles Delivering Catalase Enhances the Treatment for Acute Lung Injury
Tactile-Transparent Wearable Sensor for Clinician-Friendly Pulse Wave Velocity Monitoring and Cardiovascular Risk Profiling
Combining Microfluidic Assessment with Encoded Hydrogel Microparticle-Based Immunoassay for Anti-Interleukin Drug Repurposing of Pulmonary Fibrosis Therapy
Passive Monitoring to Active Regulation: Closed-Loop Piezoelectric Theranostic Platform Enabling On-Demand Vagus Stimulation for Terminating Inappropriate Sinus Tachycardia
Cardiomyocyte-Based Multimodal Biosensing Platform for Dynamic Functional Assessment of Bioinspired Engineered Respiratory Virus-Induced Myocarditis
Homotransplantation of Engineered Macrophages with Surface-Modified Nanomedicines for Mitigating Myocardial Ischemia–Reperfusion Injury
Tolerogenic Dendritic Cell- and M2 Macrophage Polarization-Inducible Hybrid Nanoparticles Alleviate Asthma in Mice
Targeting Senescent Alveolar Type 2 Cells with a Gene-Editable FePt Dual-Atom Catalyst for Mitigating Idiopathic Pulmonary Fibrosis
25
Nonlinear relationships of fibrin network structure as a function of fibrinogen and thrombin concentrations for purified fibrinogen and plasma clots
Magnesium leachates suppress inflammatory phenotype of vascular smooth muscle cells by downregulating the NF-κB p50/KLF5 signaling
Homocysteine and cholesterol in the biomechanics and structural remodeling of the aorta during the development of atherosclerosis
The correlation between the deterioration of microstructural evolution and mechanical properties in human ascending aortas with and without dissections
An efficient framework to assess the predictive value of 4D ultrasound-based wall motion indices for abdominal aortic aneurysm rupture risk stratification
Valve endothelial monolayer fissuring and interstitial matrix fracture triggers calcific lesion formation via GTPase signaling
Lung tissue viscoelasticity is preserved with bleomycin-induced fibrosis in mice
Regional mechanical and microstructural variations in ascending thoracic aortic aneurysms influenced by tricuspid and bicuspid aortic valves
Multi-targeted ROS-responsive self-immolative nanoparticles for releasing hydrogen sulfide and in situ binding of Cell-Free DNA in blast-induced acute lung injury
Mechanical characterization of infarcted porcine hearts using left anterior descending and left circumflex coronary artery models
Inhaled biomimetic nanoparticles enhance pulmonary delivery of tetrandrine and pirfenidone for the treatment of idiopathic pulmonary fibrosis
Innate type 2 lymphocytes trigger an inflammatory switch in alveolar macrophages
A Unified Finite Element Framework for Cardiac Growth and Remodeling in Mitral Regurgitation Incorporating Fiber Reorientation and Baroreflex
Recovery of coronary artery distensibility after two and four years in vivo degradation of a resorbable magnesium-based scaffold
Artificial intelligence-assisted multiscale lung modeling to predict alveolar septal wall stress
Calcification and Structural Damage Together Accelerate Porcine Pericardium Failure
Micromechanical heterogeneity in abdominal aortic aneurysms is associated with rupture risk
The ICE-AFIB trial: A multicenter prospective investigational device exemption (IDE) trial using cryosurgical ablation for atrial fibrillation during concomitant cardiac surgery
Comparative biomechanical and structural evaluation of region-specific stented and non-stented ex vivo perfused human thoracic aortas
A photodriven nano-extinguisher alleviates acute bacterial infections via toll-like receptor 4-regulated immune response
Nanoparticles coated with immune cell hybrid membranes for targeted delivery of janus kinase inhibitors and synergistic treatment of autoimmune myocarditis
The porcine abattoir blood model — Bridging the gap between human and porcine blood for in-vitro testing
Injectable protein hydrogel microspheres with reactive oxygen species-responsive nitric oxide release for cardiac protection against ischemia/reperfusion injury
Biomaterial-based 3D human lung models replicate pathological characteristics of early pulmonary fibrosis
Human heart-on-a-chip model emulates structural and functional characteristics of diastolic dysfunction and reveals a beneficial role for senolytics
8
An Inhalable Enzyme‐Peptide Nanogel for Enhanced Pulmonary Fibrosis Therapy
Raman Microscopy at the Organic–Inorganic Interfaces in Human Calcified Aortic Valves Shows the Co-Existence of Whitlockite Crystals and Carbonated Hydroxyapatite-Mineralized Collagen Fibrils
A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis
A Bespoke Programmable Interpenetrating Elastomer Network Composite Laryngeal Stent for Expedited Paediatric Laryngotracheal Reconstruction
Dual-Defect Engineering of LDH-Based Nanozymes to Enhance Antioxidative Effects in Ischemia Stroke-Reperfusion Injury
Inhalable Lipid Nanoparticles with Mucus Clearance and ROS Scavenging Properties for Acute Lung Injury Treatment
A Biomimetic Epidermal Sensing Sucker via Stress Excitation for Personalized Cardiovascular Monitoring
Wearable Multifunctional Epidermal Patch for Continuous and Reliable Blood Pressure Monitoring with Simultaneous Tracking of Physiological Health States
1
An Extravascular Synergistic Cocktail Therapeutic Strategy Based on Lanifibranor Loaded Self-Healing Bioelastomer for Abdominal Aortic Aneurysms
9
Nutritional anemia is associated with increased risk of severe COPD exacerbations: a prospective cohort study
Association between BMI-discordances in cardiometabolic biomarkers and risk of incident heart failure: a prospective cohort study
A clinical study examining the effects of dietary nitrate on urinary N-nitrosamines
The influence of hemoglobin measurement error on accuracy of population anemia surveillance: results from mathematical simulations
Prognostic value of adiposity indices in anticoagulated patients with atrial fibrillation: The prospective Murcia AF Project III cohort
Comparison of Hemoglobin Measurements from Venous and Capillary Blood from the same individual using HemoCue 301 and Automated Hematology Analyzer in a cross-sectional Community-Based Study in India.
Gut microbiota-derived pro-inflammatory biomarkers and risk of coronary artery disease: a prospective study among US men and women
Interaction between dietary cholesterol intake and genetic variants for cholesterol absorption in relation to coronary artery disease mortality: a prospective analysis in the Singapore Chinese Health Study
Heme iron versus ferrous iron salts to treat iron deficiency anemia in Gambian children: randomized controlled trial
10
Changes in PM2.5 exposure due to residential relocation and mortality among U.S. Veterans
Antibiotic treatment for non-specific upper respiratory tract infections and exacerbation risk in children with asthma: A target trial emulation study
Longitudinal associations of the gut microbiome with arterial stiffness in US adults: findings from the Baltimore Longitudinal Study of Aging
Neighborhood-level socioeconomic position and mortality among children born with critical congenital heart defects
The effects of a smoking cessation intervention on mortality after a 32.5-year follow-up period: a randomized clinical trial
The effect of damp housing on psychological distress: does respiratory health matter?
The protective effect of housing affordability on childhood asthma risk: a longitudinal fixed-effects analysis
Obstructive sleep apnea and functional hearing loss over 8 years: results from the National Health and Aging Trends Study
Home dampness and molds and occurrence of respiratory tract infections in the first 27 years of life: the Espoo Cohort Study
Use of censored data methods to estimate blood pressure percentiles in US adults
1
Reproductive factors and the risk of incident peripheral arterial disease hospitalisation or death: A cohort study of UK Biobank participants
5
PPARα Deficiency Induces Vascular Pathologies through Endothelial Senescence in Diabetic Retinopathy
Cullin 2 elevates Warburg effect to accelerate the development of hypoxic pulmonary hypertension
Specialized pro-resolving mediators MaR1 and LXA4 resolve inflammation during acute chemical lung injury in the absence of neutrophils
The substructure of the endothelial glycocalyx in rat aorta and its interaction with the low-density lipoproteins (LDL)
Endothelial cell STING regulates IL6 production and is required for pathological cardiac hypertrophy and contractile dysfunction in experimental heart failure
72
Occupational Exposure to Dust and Fumes Increases Risk for Future Adverse Clinical Outcomes
The frequent exacerbator phenotype in bronchiectasis revisited: Data from EMBARC registry
Identification of Pulmonary Arterial Hypertension Patients with Venous or Capillary Involvement
Defining disease stability in COPD: Evidence from Phase 3 clinical trials
Mepolizumab Efficacy in COPD: Insights from Longitudinal Patterns of Blood Eosinophil Counts and Their Variability Across Three Clinical Trials
Early neutrophil and persistent eosinophil-associated gene signature in childhood asthma
Meaningful Thresholds for Change in Quantitative CT–Derived Fibrosis Extent in Idiopathic Pulmonary Fibrosis
Astegolimab for COPD With Frequent Exacerbations: Pooled Analysis of the ALIENTO and ARNASA Trials
Tezepelumab in Real-World U.S. Patients with Severe Asthma Across Phenotypes and Underrepresented Populations: The Phase 4 PASSAGE Study
Single-cell Sequencing Unveils A Profibrotic Macrophage and Infiltrating Monocyte Niche in the Bronchoalveolar Lavage of Patients with Chronic Obstructive Pulmonary Disease
Aroxybutynin and atomoxetine (AD109) for obstructive sleep apnea: a randomized phase 3 trial (SynAIRgy)
Dupilumab in COPD: A Pooled Analysis of Emergency Department Visits, Hospital Admissions, and Systemic Corticosteroid Use
From mild-to-moderate to severe asthma: Risk factors and patient profiles from the NORDSTAR cohort
Post-Tuberculosis Lung Disease in Treated Extra-Pulmonary Tuberculosis
Effectiveness of automatically-adjusted vs manually-adjusted noninvasive ventilation in obesity hypoventilation syndrome: a randomized clinical trial
Nerandomilast in idiopathic pulmonary fibrosis: data from the whole follow-up period of the FIBRONEER-IPF trial
Sub-phenotypes of pneumonia defined by pulmonary histopathological features
Idiopathic Pulmonary Fibrosis Risk Loci in East Asian Populations Mirror those of European Populations
Deupirfenidone Compared with Pirfenidone and Placebo in Idiopathic Pulmonary Fibrosis (ELEVATE-IPF): a Phase 2b Randomized Placebo-Controlled Trial
Phase 2b trial of inhaled imatinib for treatment of pulmonary arterial hypertension
Molecular endotypes predict differential response to immunosuppressant therapy in non–idiopathic pulmonary fibrosis interstitial lung disease
Mast Cells and Endothelial Cells Mediate Interleukin-33 and ST2 Responses in Distal COPD Lungs
Pamufetinib (TAS-115) for Chronic Fibrosing Interstitial Lung Diseases with a Progressive Phenotype: A double-blind, multicenter, phase 2b Clinical Trial
Mosaic Loss of Y chromosome associates with lung function, emphysema and epigenetic aging
Discriminative Performance and Clinical utility of COPD Exacerbation Categories for Predicting Future Exacerbations
CES1 Deficiency is Associated With Metabolic Reprograming and Endothelial Dysfunction in Pulmonary Arterial Hypertension
Pulmonary Rehabilitation is Associated with Increased 1-Year Survival in Stable COPD
Standalone Prognostication of Idiopathic Pulmonary Fibrosis Using Attention-Based Deep Learning
Clinical and transcriptomic risk factors for post-tuberculosis lung disease in a cohort of Kenyan adults
The Long-term Pneumonia Mortality Index. An International Multicenter Derivation and Validation Study for Patients with Community-Acquired Pneumonia
Identification of a conserved sequence of disease progression in Idiopathic Pulmonary Fibrosis
Motivational Interviewing and Air Cleaners for Smokers with COPD (MOVE): A Randomized, Double-Blind, Placebo-Controlled Trial
Extracellular Vesicle Cargo from Lipofibroblasts Mitigates COPD by Alveolar Type II Cell Restoration
Mucus plugs in chronic obstructive pulmonary disease are heterogeneous in size and shape and occur in relatively large airways
International validation of electronic nose technology as diagnostic tool for fibrotic interstitial lung diseases
Lower airway immunophenotyping in severe preschool wheeze reveals distinct clusters described by heterogeneity in neutrophil phenotypes
Effect of Dupilumab on Mucus Burden in Patients with Moderate-to-Severe Asthma: The VESTIGE Trial.
Lung Involvement of Myeloid-Lymphoid Neoplasia with Eosinophilia
Mucus Plugs-associated Gene Expression Identifies Pathophysiology Shared with Chronic Bronchitis.
Phenotyping Asthma and/or COPD Using 129Xe MRI and Comprehensive Physiologic Testing.
Patient Factors and Clinical Efficacy of Early Identification and Treatment of COPD and Asthma.
p300-Dependent Modulation in Regulatory T Cells Plays a Crucial Role in Allergic Asthma.
Outcomes of a Typical Fibrotic Hypersensitivity Pneumonitis Pattern on Chest Computed Tomography
Airway Epithelial Heterogeneity and Mucus Plugging in Asthmatic Bronchioles.
Upper Airway Microbiome, Mucociliary Function, and Clinical Outcomes in Bronchiectasis: Data from the EMBARC-BRIDGE Study.
Cardiopulmonary Hemodynamic Determinants of Long-Term Survival in Sickle Cell Disease: Insights from the ETENDARD Study.
Randomized Sham Controlled Trial of Targeted Lung Denervation in Patients with COPD (AIRFLOW-3).
Mucus Plugs Correlate with Small Airway Remodelling in Asthma: A Case-Control Study.
Associations of High Attenuation Area-related Proteomic Biomarkers with Fibrotic or Subpleural Interstitial Lung Abnormalities.
One-Year Change in Quantitative Computed Tomography Is Associated with Meaningful Outcomes in Fibrotic Lung Disease.
Ionocyte CFTR Coordinates Chloride Absorption and Secretion to Balance Airway Fluid.
Active Antigen-Specific Adaptive Immune Responses Are Shared among Patients with Progressive Fibrotic Interstitial Lung Disease.
Distinct Morphological Types of Small Airway Obstructions in Smokers with Emphysema and End-Stage COPD.
Impact of Sleep Apnea on Perivascular Diffusivity and Cognition: A 4-Year Prospective Cohort Study.
Impact of Elexacaftor/Tezacaftor/Ivacaftor on Glucose Tolerance and Abnormal Glucose Metabolism: A Phase 3b, Open-Label Clinical Trial.
Inflammation and Obesity Correlate in Pulmonary Hypertension but Associate with Diverging Outcomes.
Hemodynamics and Phosphodiesterase-5 Inhibitor Treatment Associated with Survival in ILD-PH: A PVRI GoDeep Meta-Registry Analysis.
A Large-Scale Single-Cell Atlas Reveals the Peripheral Immune Panorama of Bacterial Pneumonia.
Non-Coding DNA Variants Increase the Genetic Diagnostic Yield in Primary Ciliary Dyskinesia.
Clustering Patients with Pulmonary Hypertension Using the Plasma Proteome
Proteomic Biomarkers of Survival in Non–Idiopathic Pulmonary Fibrosis Interstitial Lung Disease
Right Ventricular Strain and Outflow Tract Velocity Time Integral Are Associated with Mortality in Critically Ill Patients with Pulmonary Embolism
Visual and Quantitative Interstitial Lung Abnormality Progression in COPDGene.
A Long-Term Physical Activity Coaching Program for Patients with COPD: A Randomized Controlled Trial.
A Quantitative Imaging Measure of Progressive Pulmonary Fibrosis.
Molecular Phenotyping of Sepsis and Differential Response to Fluid Resuscitation.
Endotypes of Pseudomonas aeruginosa Infection in Bronchiectasis Are Associated with Inhaled Antibiotic Response: Results from Two Randomized, Double-Blind, Placebo-controlled Phase III Trials (ORBIT 3 and ORBIT 4).
The Plasma Proteome in Community-acquired Pneumonia: Pathophysiology, Outcome and 10-Year Risk.
Lipid Ratios for Diagnosis and Prognosis of Pulmonary Hypertension
Deep Learning Estimation of Small Airway Disease from Inspiratory Chest Computed Tomography: Clinical Validation, Repeatability, and Associations with Adverse Clinical Outcomes in Chronic Obstructive Pulmonary Disease
Associations of Prepandemic Lung Function and Structure with COVID-19 Outcomes: The C4R Study
Dual αvβ6 and αvβ1 Inhibition over 12 Weeks Reduces Active Type I Collagen Deposition in Individuals with Idiopathic Pulmonary Fibrosis: A Phase 2, Double-Blind, Placebo-controlled Clinical Trial
18
Early Diagnosis and Longitudinal Monitoring of Myocardial Infarction in Tuberculosis Patients with High-Throughput Suspension Array Testing of a Biomarker Panel
Toward Precision Electrochemical Sensing of CFTR Function in Cystic Fibrosis Models
Toward a Comprehensive Raman Analysis of Functional Cells With Structured Optical Traps
Breath Aerosol Admittance Orthonormal to Sweat Conductivity as a Reliable 2-D Diagnostic Criterion for Cystic Fibrosis
Orthogonal NIR/Ratiometric Probe for Simultaneous Imaging of NO and ATP in Acute Lung Injury: Elucidating Metabolic Dysregulation and Therapeutic Screening
Fluorescent G-Quadruplex Nanowire-Enabled One-Pot Detection of Multiple Acute Myocardial Infarction-Related miRNAs
Real-Time Monitoring of Intraplaque Furin in Atherosclerotic Mice during Pneumonia and Dexamethasone Treatment
Surface Acoustic Wave-Based Assessment of Red Blood Cell Viability Following Cryopreservation
Wash-Free and Simultaneous Imaging Assay of PCSK9 and ApoB Proteins for Efficient Screening and Efficacy Evaluation of the PCSK9 Inhibitors
A Superoxide Anion-Responsive NIR Fluorogenic Probe Unravels Aucubin’s Dual-Axis Therapeutic Mechanism in Hypoxic Pulmonary Hypertension via Ferroptosis Suppression and Oxidative Injury Mitigation
Near-Infrared Fluorogenic Probe Enables Real-Time Imaging of HOCl to Reveal MAR1-Mediated Suppression of Pyroptosis in Limb Ischemia-Reperfusion Injury
Shear Stress-Induced Microstructure Remodeling of Human Bicuspid Aortopathy Revealed by Nonlinear Optical Microscopy
Etiology-Agnostic Diagnosis of Early Myocardial Ischemia via AI-Driven Label-Free Spectral Histopathology
Microsensor Array for the Electrochemical Analysis of Hydroxyurea in Blood Samples of Children Affected by Sickle Cell Anemia
Doxorubicin-Induced Toxicity and Bisoprolol-Protective Efficacy for Cardiomyocytes Monitored by Scanning Electrochemical Microscopy
A QCM-Based Biosensor to Detect HIT-like Antibodies: Differentiating KKO from RTO via FcγRIIA Interactions
Nanopore-Based Strategy for Single-Nucleotide Mutation Detection in Sickle Cell Disease Using Anthracycline Probes
Detection and Analysis of Reactive Oxygen Species (ROS): Buffer Components Are Not Bystanders
8
Higher versus Routine Intraoperative Blood Pressure Targets in Noncardiac Surgery: A Systematic Review and Meta-analysis with Trial Sequential Analysis of Randomized Trials.
Capnodynamic Cardiac Output Assessment in a Porcine Model of Aorto-Pulmonary Shunt.
Overdose propofol emulsion induces PANoptosis in human peripheral neutrophils in an ex vivo model.
High-Flow Nasal Oxygenation in Infants Undergoing Tracheal Intubation: A Single-center Randomized Controlled Trial.
Intraoperative Cardiac Events in Pediatric Patients with Congenital Heart Disease Undergoing Noncardiac Procedures: Analysis of a Large Multicenter Registry.
TEG® 6s heparin neutralization cartridge for hemostatic assessment of patients undergoing cardiovascular surgery.
Cardiac Biomarkers and Risk Stratification in Liver Transplantation for Acute-on-Chronic Liver Failure: Refining Current Risk Models for Improved Prediction of Post-transplant Mortality.
Transfusion of Amustaline/Glutathione Pathogen-Reduced Red Blood Cells in Cardiac Surgery - A Randomized Phase III Clinical Trial
2
Lighting up Ferroptosis Propagating via the Lung‐Heart Axis Exacerbates Cardiovascular Disease Through in Situ Imaging
Self‐Assembled Metal‐Polyphenol Colchicine Nanoparticles Targeting Oxidative Stress and Inflammation for Treatment of Atherosclerosis
5
Dexamethasone Treatment Regimen and Clinical Outcomes in Children With Asthma Exacerbations
The Limit of Detection in the Emergency Department Trial (LEGEND): A Stepped-Wedge Cluster Randomized Trial to Rule Out Acute Myocardial Infarction and Reduce Hospital Length of Stay for Patients Presenting to the Emergency Department
Evaluation of Out-of-Hospital Use of a Valsalva Assist Device in the Emergency Treatment of Supraventricular Tachycardia
Opportunistic Screening for Atrial Fibrillation With Continuous ECG Monitoring in the Emergency Department
Incidence and Clinical Relevance of Echocardiographic Visualization of Occult Ventricular Fibrillation: A Multicenter Prospective Study of Patients Presenting to the Emergency Department After Out-of-Hospital Cardiac Arrest
7
Proximal Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea in the OSPREY Study : A Randomized Controlled Trial.
Short Versus Longer Antibiotic Duration for Community-Acquired Pneumonia : A Multicenter Target Trial Emulation.
Neither Metformin nor Ursodeoxycholic Acid Effectively Treats Postacute Sequelae of COVID-19 : A Randomized Clinical Trial.
The Risk for Bleeding in Patients With Atrial Fibrillation From Concomitant Use of Apixaban or Rivaroxaban With Diltiazem Compared With Metoprolol.
Effectiveness of Sodium-Glucose Cotransporter-2 Inhibitors Versus Glucagon-like Peptide-1 Receptor Agonists on Diabetic Foot Disease : An Emulated Target Trial.
Effectiveness and Safety of Statins in Type 2 Diabetes According to Baseline Cardiovascular Risk : A Target Trial Emulation Study.
Effect of Systolic Blood Pressure Measurement Error on the Cost-Effectiveness of Intensive Blood Pressure Targets.
4
Apixaban Versus Aspirin and Risk of Hemorrhage in the ARCADIA Trial
<atl>Prospective, Multicenter Evaluation of Transcarotid Artery Revascularization in Standard‐Risk Patients: 30‐Day Outcomes of the scpROADSTER/scp 3 Study</atl>
Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Have Distinct Prediagnostic Blood Biochemical Profiles
Carotid Revascularization Versus Medical Management for Ischemic Stroke with Ipsilateral Carotid Web: A Systematic Review and Meta‐Analysis
5
Bivalirudin use and Outcomes in Neonates With Congenital Diaphragmatic Hernia Managed With Extracorporeal Life Support.
“Textbook Outcome” in Endovascular Aortic Repair is Associated With Improved One-year Survival
A Frozen Elephant Trunk Technique to Reduce Circulatory Arrest Time in Hybrid Aortic Arch for Acute Aortic Dissection: Early and Midterm Outcomes in a Multicentric Cohort of 153 Patients.
Randomized Controlled Trial of New Oral Anticoagulants Versus Warfarin for Post Cardiac Surgery Atrial Fibrillation: The NEWAF Trial.
Transcarotid Artery Revascularization Versus Carotid Endarterectomy With and Without High-Risk Criteria: A National Target Trial.
7
Autologous stem cell transplantation (ASCT) for Refractory juvenile-onset systemic sclerosis (JSSc)
Efficacy and safety of nerandomilast in patients with autoimmune disease-related progressive pulmonary fibrosis in the FIBRONEER-ILD trial
Altered AP-1, RUNX, and EGR chromatin dynamics drive human fibrotic lung disease
Use of statins and its association with major adverse cardiovascular events with tofacitinib vs TNF inhibitors in patients with rheumatoid arthritis with and without atherosclerotic cardiovascular disease
Two-year efficacy and safety of anti-interleukin-5/receptor therapy for eosinophilic granulomatosis with polyangiitis
Effects of different B-cell-depleting strategies on the lymphatic tissue
Disease Trajectories and Glucocorticoid Exposure in VEXAS Syndrome Treated with Cytokine-Directed Therapies
2
Label-free, high-spatiotemporal resolution microwave-induced thermoacoustic imaging for functional cardiac phenotyping and myocarditis detection
Pulse wave signal analysis and finding the quantitative indicators of cardiovascular health
7
Feasibility and Preliminary Effects of Inspiratory Muscle Training in Patients with Knee Osteoarthritis Awaiting Total Knee Arthroplasty: An 8-week, Pilot Randomized Controlled Trial
The Current Status of Cardiac Rehabilitation in China: A Cross-sectional National Survey
Leisure-time physical activity and mortality in chronic obstructive pulmonary disease: a nationwide cohort study
Is the Six-Minute Step Test Feasible and Safe for Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation? Exercise Test in Bone Marrow Transplant
Non-cardiac Pain Prevalence, Pain Intensity, Pain Interference, Sleep, and Cardiopulmonary Function in Outpatient Cardiac Rehabilitation
The impacts of ACC/AHA stage A, B, and C heart failure on improvement efficiency in activities of daily living in patients with disabilities who underwent inpatient rehabilitation
Diabetic Hand Complications in Prediabetes: A Controlled Observational Study
18
Lung ultrasound for the detection of radiological progression of interstitial lung abnormalities in patients with rheumatoid arthritis
Impact of Evolving Treatment Patterns on Interstitial Lung Disease Progression in Systemic Sclerosis Using the European Scleroderma Trials and Research Database
Interstitial Lung Disease in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis: A European Multicenter Study
Performance of the Predicting Risk of Cardiovascular Disease Events Calculator in Rheumatoid Arthritis
Single‐Cell Analysis Reveals Peripheral Helper T Cells in Rheumatoid Arthritis–Related Interstitial Lung Disease
<atl>Interleukin‐18 levels are associated with disease course in patients with Still's disease treated with scpIL/scp ‐1 inhibitors</atl>
Distinct natural killer cell signature in still's disease: Insights from a multinational immunome project consortium for autoinflammatory disorders
Interleukin‐33 Promotes Interstitial Lung Disease in Idiopathic Inflammatory Myopathy via ERK‐Mediated Epithelial‐Mesenchymal Transition: ERK as a potential therapeutic target
Drugs induced Raynaud's phenomenon and underlying mechanism: a disproportionality analysis from the WHO pharmacovigilance database
Glucagon‐Like Peptide‐1 Receptor Agonist Use and the Risk of Adverse Cardiac and Kidney Outcomes Among Patients with Systemic Lupus Erythematosus and Lupus Nephritis
The Effect of Benralizumab and Mepolizumab on Use of Oral Glucocorticoids in Patients with Eosinophilic Granulomatosis with Polyangiitis
Performance of an Idiopathic Pulmonary Fibrosis Derived Multibiomarker Panel for Rheumatoid Arthritis‐Associated Interstitial Lung Disease
Serum cytokine profiling differentiates underlying diseases in cytokine storm syndrome
Long‐Term Safety and Efficacy of Mepolizumab in Eosinophilic Granulomatosis With Polyangiitis
Comparative Cardiovascular Safety of Nonsteroidal Anti‐Inflammatory Drug Versus Colchicine Use When Initiating Urate‐Lowering Therapy Among Patients With Gout: Target Trial Emulations
Longitudinal Analysis of Somatic Mosaicism and Clonal Hematopoiesis in Cryopyrin‐Associated Periodic Syndrome
Clinical manifestations of scpVEXAS/scp syndrome across a broad spectrum of scpUBA1/scp mutation burden
B cells and systemic sclerosis interstitial lung disease
28
CD49d governs immune synapse formation through actin rearrangements and synchronizes BCR signaling in CLL
Lenalidomide plus rituximab for previously untreated advanced follicular lymphoma: the 10-year RELEVANCE trial analysis
Venetoclax combinations in untreated CLL: 5-year results and patient-reported outcomes analysis of the CLL13/GAIA trial
Fixed-duration VenO vs FCR/BR in fit patients with untreated CLL: primary analysis of the phase 3 CRISTALLO trial
Patient-derived lymphoma spheroids reveal predictive markers of glofitamab resistance in relapsed/refractory B-NHL
BET inhibition blunts antibody production and macrophage-mediated fibrosis to restore lung function in murine cGVHD
Clusterin maintains hemostatic equilibrium by stabilizing VWF multimers in plasma
CSNK1E sustains stemlike drug persistence in diffuse large B-cell lymphoma
Evolution of tumor subclones and T-cell dynamics underlie variable ibrutinib responses in Waldenström macroglobulinemia
An optimized CRISPR-Cas12a genome-wide screen reveals PTPA phosphatase pathway in fetal hemoglobin silencing
Treatment-related outcomes and patterns of relapse in secondary CNS involvement by large B-cell lymphoma
A decade of ibrutinib for CLL with and without TP53 aberration: final report on an investigator-sponsored phase 2 study
Clonal hematopoiesis and lymphoma-associated mutations in hematopoietic progenitors in B-cell non-Hodgkin lymphoma
Ultraprecision therapy for type 1 vs type 2 CALR+ MPN by dual epitope targeting that restores ruxolitinib sensitivity
Heme-induced activation of the TLR3/TRIF–IFN-I–CCL2 pathway contributes to kidney injury in sickle cell disease
The landscape and evolution of clonal hematopoiesis in chronic lymphocytic leukemia
VEXAS anemia is a mosaic erythroblastopenia
PROs vs clinician-reported adverse events in a large clinical trial: findings from the phase 3 POLARIX study
A phase 2 study of zanubrutinib in combination with rituximab and lenalidomide in de novo diffuse large B-cell lymphoma
TNFα signaling restores steady-state hematopoiesis in a TNFαKO mouse model of anemia of inflammation
Modeling the HLH immune synapse uncovers critical roles for IS termination, cytokine intensity, and target cell death
TCA cycle mode switch determines the fate of pirtobrutinib-tolerant persister cells in mantle cell lymphoma
Delineating iMpl/i-dependent and -independent phenotypes of iJak2/i V617F–positive MPNs in vivo
A novel cause of type 1 Von Willebrand Disease: impaired exocytosis of Weibel-Palade bodies due to biallelic MADD variants
Clinical phenotype and pathophysiological mechanisms underlying qualitative low VWF
Real-world outcomes of patients with aggressive B-cell lymphoma treated with epcoritamab or glofitamab
A non-coding mutation within the NOTCH1 gene initiates oncogenic NOTCH signaling via wild type NICD stabilization in CLL
Rapid ADAMTS13 activity assays for thrombotic thrombocytopenic purpura: a systematic review and meta-analysis
2
Haematopoietic stem cell transplant versus immune-reconstitution therapy in relapsing multiple sclerosis
Dominant rhabdomyolysis linked to a recurrent ATP2A2 variant reducing SERCA2 function in muscle
10
Frailty and the Efficacy and Safety of Surgical vs Endovascular Revascularisation: A Post Hoc Analysis of the BEST-CLI Trial
Development of a standard definition of ‘no-option’ and ‘poor-option’ for revascularization in chronic limb-threatening ischemia
Plain balloon angioplasty with or without bare-metal stenting versus drug-coated balloon angioplasty with or without bare-metal stenting versus primary drug-eluting stenting in patients requiring femoropopliteal, with or without infrapopliteal, endovascular revascularization for chronic limb-threatening ischaemia: BASIL-3 within-trial health economic analysis
Retrospective population-based cohort study on the risk of cardiovascular disease among oesophageal cancer survivors
<atl>Open surgery iversus/i branched endovascular repair of the aortic arch in residual dissections after type A surgical repair</atl>
Stroke risk and mid-term survival by proximal extent of endovascular aortic repair
Open thoracoabdominal aortic aneurysm repair: results from a national service
Long-term mortality rate and clinical outcomes associated with femoro-popliteal drug–coated balloon angioplasty and drug-eluting stents in chronic limb-threatening ischaemia: an analysis of the BASIL-3 RCT
A comparison of women and men with small abdominal aortic aneurysms
Decreasing aortic diameter and decreasing prevalence of infrarenal aortic aneurysms in a population-based screening programme
2
Axes of biological variation in diffuse large B cell lymphoma
Distinct follicular T cell subsets regulate lymphoma progression and outcomes
3
A single-cell time-series atlas of endothelial cell embryonic development
A triple-node heart-brain neuroimmune loop underlying myocardial infarction
Renal PIEZO2 is an essential regulator of renin
3
An infant nasal microbial gene atlas uncovers intervention-driven microbiome shifts and salt-resistant pathogen expansion
Gut-microbiota-derived indole sulfate promotes heart failure in chronic kidney disease
Pseudomonas infections persisting after CFTR modulators are widespread throughout the lungs and drive lung inflammation
3
NAD-dependent redox control enables endothelial quiescence and vascular stabilization during angiogenesis
Deletion of Mfn2 in endothelial cells triggers a mitohormetic response that improves systemic metabolism and healthspan in mice
Cystine import and oxidative catabolism fuel vascular growth and repair via nutrient-responsive histone acetylation
5
Patient-derived organoids reveal ductal dysfunction and CFTR-modulator responses in chronic pancreatitis
Engineered CAR-monocytes coordinate fibrosis clearance and cardiac regeneration following myocardial infarction
Human pluripotent stem cell-derived atrioventricular node-like pacemaker cells exhibit biological conduction bridge properties
Injury-induced Clusterin+ cardiomyocytes suppress inflammation and promote regeneration in neonatal and adult hearts by reprogramming macrophages
Targeting lysozyme 2 in endocardium promotes rapid recovery by modulating remote injury signals
1
Size-tunable hemoglobin oxygen carriers with antioxidant and pro-angiogenic functions for wound healing
3
Dual-site recognition leads to a ratiometric fluorescent probe for norepinephrine: quantitative detection and visualization for in-depth understanding of hypertension
A natural ultrasound-triggered nitric oxide booster for endothelial dysfunction therapy
A malondialdehyde-activated fluorescent probe reveals lysosomal dysfunction in atherosclerosis
98
Phenotyping of pulmonary arterial hypertension associated with congenital heart disease using latent class analysis: insights from a national prospective registry
Prevalence and Risk Factors of Preserved Ratio Impaired Spirometry in People With HIV and Matched Population Control Participants
Integrative Phenogroups Based on Lung Imaging and Spirometry from Young Adulthood to Midlife and Associations with Subclinical Cardiac Structure and Function
Comprehensive Evaluation of Night-to-Night Variability in PSG Metrics and AHI–Based Diagnostic Reclassification
Longitudinal Changes in Lung Morphology and Perfusion Detected by Magnetic Resonance Imaging in Patients with Primary Ciliary Dyskinesia From Infancy Through Adulthood
Accuracy of clinical phenotype for diagnosing adults with primary ciliary dyskinesia
Chest Radiograph-Derived Age Acceleration as an Early Marker of Pulmonary Dysfunction in Middle-Aged Asians
Characterization of CT-Derived Pulmonary Vascular Abnormalities Associated with Pulmonary Hypertension in Chronic Lung Disease
Higher respiratory muscle oxygen cost of breathing during exercise in heart failure with preserved ejection fraction
Moving Beyond Responders: A post-hoc Analysis Identifying Criteria for Chronic Cough Control
The Importance of Postprocessing Methods for Assessing Right Ventricular Volumes and Function in Patients With Pulmonary Hypertension
Pretreatment With Mono or Dual Pulmonary Hypertension-Targeted Medical Therapy in Patients Undergoing Balloon Pulmonary Angioplasty
Effectiveness of Cystic Fibrosis Transmembrane Conductance Regulator Modulator Therapy on Risk of Death for Individuals With Cystic Fibrosis
Clinical response progression to benralizumab using computed tomography: Prognostic BenraliScan study
Associations of mucus plug with prognosis in chronic obstructive pulmonary disease: A systematic review and meta-analysis
Three-Year Outcomes of Proximal Hypoglossal Nerve Stimulation in OSA
Impact of pulmonary arterial hypertension therapies on gas exchange in portopulmonary hypertension
Risk Stratification in Patients With Chronic Thromboembolic Pulmonary Hypertension Following Pulmonary Endarterectomy
Eosinophil Counts in Adults With Asthma Treated with Anti-IL-4Rα Rademikibart
Impact of Antifibrotic Adherence and Dosing on Risk of Mortality and Hospitalization in Idiopathic Pulmonary Fibrosis
Dupilumab Reduces Mucus Radiodensity and New Plug Formation in Asthma
Imaging-based Pulmonary Hypertension Phenotypes in Connective Tissue Disease-related Interstitial Lung Disease
Characterising cough and its response to therapy in hypersensitivity pneumonitis
Eosinophilic vs Non-Eosinophilic Acute Exacerbations of COPD and Subsequent Cardiovascular Event
Admission Eosinophil Count Is Associated With Hospital Resource Use in Community-Acquired Pneumonia
Fixed-Pressure vs Autoadjusting CPAP for BP Control in OSA
Effects of a Sea-Level Stay on Pulmonary Hemodynamics in Patients With Pulmonary Arterial Hypertension Living in Quito Near 2,850 m
The Impact of Disease Severity and Symptoms on Anxiety and Depression in Individuals With Idiopathic Pulmonary Fibrosis
Efficacy and Safety of Ensifentrine in Chinese Participants With COPD: The ENHANCE-CHINA Randomized Clinical Trial
Assessment of Abdominal Adiposity in OSA Using Combined PET Imaging and MRI
Association of Inhaling Marijuana With Asthma Attacks
The Epidemiology of Cryptogenic Organizing Pneumonia
Association of Sleep-Related Hypoxemia With Survival in Patients With Non-Small Cell Lung Cancer
OSA Is Associated With Enhanced Coronary Collateral Circulation and Reduced Myocardial Injury During Acute Coronary Syndromes
The Minimal Important Difference in N-Terminal Pro-Brain Natriuretic Peptide in Pulmonary Hypertension
Matrix Metalloproteinase 12 Improves the Differentiation of Idiopathic Pulmonary Fibrosis and Fibrotic Hypersensitivity Pneumonitis and Associates With Antigen Response Pathways
Demographic and Physiological Differences Between Fibrotic and Nonfibrotic CT Subtypes of Sarcoidosis
Clinical Effectiveness and Cost-Effectiveness of Pulmonary Rehabilitation for People in Uganda With Post-TB Lung Disease
Association of High Cardiovascular Disease Risk OSA With Incident Atrial Fibrillation
Effects of a Novel Dual Phosphodiesterase 3 and 4 Inhibitor TQC3721 in Patients With COPD in China (PACER-II): A Phase 2, Multicenter, Randomized, Double-Anonymized, Placebo-Controlled Trial
Understanding Pulmonary Fibrosis in Pediatric Interstitial Lung Disease: A Comprehensive Analysis
Management and Long-Term Outcomes of Persistent Tachypnea of Infancy/Neuroendocrine Cell Hyperplasia of Infancy: A European Multicenter Retrospective Study
A Randomized, Placebo-Controlled, Double-Blind, Crossover Trial of Inhaled Nitric Oxide in Patients With Mild-to-Severe COPD
Sex does not modify prediction of asthma attacks by clinical risk factors and Type-2 biomarkers
Twelve-month follow-up and economic evaluation of an alternative care provider clinic for severe sleep-disordered breathing
Exacerbation Risk by Chronic Proton Pump Inhibitor use in Obstructive Lung Diseases
Formation and Growth of a Bronchiectasis and Pulmonary NTM Multidisciplinary Program Using a Patient-Centered and Integrated Care Model Improves Outcomes
Efficacy of Anti-Inflammatory Therapies for Adults with Non-Cystic Fibrosis Bronchiectasis: A Systematic Review and Network Meta-Analysis
The Influence of Heart Failure and Ventilatory Support mode on hospital morbidity and mortality in patients with or at risk for Obesity Hypoventilation syndrome: findings from the National Inpatient Sample
Nocturnal Hypoxemia is Associated with Lower Cardiovascular Events in Patients with Acute Coronary Syndrome and Obstructive Sleep Apnea
Recovery rate from exertional desaturation is associated with disease progression and mortality risk in patients with fibrotic interstitial lung disease
Association between exertional dyspnea and obstructive sleep apnea
From Pulse to Phenotype: Sleep Apnea Endotyping for Polygraphy via Oximeter-derived Autonomic Arousal
Radiographic Fibrosis Extent Identifies Immunomodulatory Treatment Response in Hypersensitivity Pneumonitis
Incidence of new comorbidities after steroid use in patients with sarcoidosis: an international cross-sectional survey
Aspergillus fumigatus sensitization is associated with high-risk bronchiectasis
Rare variants in PAH-related genes associate with a distinct vasculopathy phenotype and worse outcomes in patients with systemic lupus erythematosus-associated pulmonary arterial hypertension
Treatment patterns in incident pulmonary hypertension patients: real-world data from the Pulmonary Hypertension Association Registry
Impact of mepolizumab on airway remodeling and inflammation in severe eosinophilic asthma
Quantitative CT in Progressive Pulmonary Fibrosis: Clinical Utility and Meaningful Threshold Definition
Initial Evaluation of the Pulmonary Hypertension Functional Classification Self-Report (PH-FC-SR) Measurement Properties: A Patient-Focused Measure
Clinician Views on Inhaler Substitution in the Veterans Health Administration
Structural and functional pulmonary MRI to predict pulmonary exacerbations in Cystic Fibrosis
Chronic thromboembolic pulmonary disease with exercise pulmonary hypertension – A non-invasive model to predict exercise hemodynamics
Clinical Outcomes in Chronic Obstructive Pulmonary Disease Patients with Disease Stability: Data from the KOCOSS Cohort
Impact of elevated Pulmonary Arterial Wedge Pressure on safety and efficacy of balloon pulmonary angioplasty in the treatment of chronic thromboembolic pulmonary hypertension.
Relationship between Framingham 10-year cardiovascular disease risk score and pulse wave amplitude drop characteristics in a sleep clinic cohort.
Cardiovascular Events in COPD: Complementary Role of Cardiac Risk and Coronary Artery Calcium Scores
Comparative outcomes and side effects of immunosuppressants and tumor necrosis factor inhibitors in sarcoidosis: a real-world data analysis
Clinical Validation of a Multidimensional Diagnostic Approach for Chronic Obstructive Pulmonary Disease in Chinese
Impact of Positive Airway Pressure Therapy on Healthcare Resource Use in Patients with Obstructive Sleep Apnea and Coronary Artery Disease
Lung Cancer Risk in Preserved Ratio Impaired Spirometry and Airway Obstruction: A UK Biobank Study
Differential effects of antifibrotic treatment on outcome prediction via serial CRPM levels in IPF
Positive Airway Pressure (PAP) Therapy Use and Healthcare Resource Utilization in Patients with Obstructive Sleep Apnea and Comorbid Insomnia (COMISA)
Acetazolamide plus Atomoxetine for Obesity Hypoventilation Syndrome Treatment A Randomized Controlled Trial
International stakeholder engagement on clinical care and research for sleep assessment and nocturnal hypoxaemia in pulmonary fibrosis
Lung Function Changes Across the Menopausal Transition: A Longitudinal Analysis of Annual Exams
Inter-session Variability in Single-Breath Diffusing Capacity of Carbon Monoxide
Developing and Validation of a Multimodal-based Machine Learning Model for Diagnosis of Usual Interstitial Pneumonia: a Prospective Multicenter Study
Breathlessness abnormality is best assessed at peak exercise during incremental cardiopulmonary cycle exercise testing
Association between betel quid consumption and respiratory disease mortality in a prospective Bangladeshi cohort
How using different oximeters may affect clinical decision: a method comparison study in patients under CPAP or non-invasive ventilation
Pediatric bronchiectasis action management plan to improve clinical outcomes: An RCT
Novel hypoglossal stimulation markedly improves airflow and airway collapsibility in OSA
The Dose-Response of Inhaled Corticosteroids in Combination Inhaled Corticosteroid/Long Acting Beta2-Agonist Maintenance Therapy for Asthma: A Systematic Review and Meta-Analysis
An inventory of clinical sarcoidosis status in the United States
Procedure Patterns and Survival in Advanced Non-Small Cell Lung Cancer with Malignant Airway Obstruction: A SEER-Medicare Analysis
Intermittent Asthma and Risk of Severe Exacerbation in Children
Inflammatory and mucociliary dysfunction based endotypes across the spectrum of chronic airway diseases
Failure to report sex-specific risk factors in heart failure with preserved ejection fraction research: a scoping review
Artificial Intelligence-Based Echocardiography in Pulmonary Arterial Hypertension
Hypoxic Burden is Associated with Cardiovascular Events: A Risk Stratification Analysis of the RICCADSA Cohort
Geographical Distribution of Phase II/III Pharmaceutical Randomised Controlled Trials in Adults with Interstitial Lung Disease
Mortality Outcomes and ACE Inhibitor Use in Patients with Idiopathic Pulmonary Fibrosis
Clustering Patients With Chronic Cough Using Reported Sensations and Triggers: Results from the Triggers and Sensations Provoking Coughing Questionnaire
Incidence of discordant pleural fluid exudates and diagnostic patterns – a retrospective cohort study
Beryllium Lymphocyte Proliferation Test: Differential Diagnosis of Sarcoidosis and Chronic Beryllium Disease
The Impact of the Unknown: Patient Experiences with Uncertainty in Sarcoidosis
105
Advancing Quality in the Evaluation, Surveillance, and Management of Aortic Stenosis: A Report From the AHA Target: AS Registry.
Vacuolar H+-ATPase Preserves Cardiolipin Homeostasis Through the Lysosomal-Mitochondrial Axis to Restrain Cardiac Aging.
Sirolimus-Eluting Balloon With Provisional Stenting Versus Systematic Drug-Eluting Stent Implantation to Treat De Novo Coronary Lesions: A Randomized, Open-Label, Noninferiority Trial
Endothelial SHMT2 Drives Pulmonary Vascular Remodeling Through Noncanonical Pathway in Pulmonary Hypertension.
Heart Rate and Cardiovascular Outcomes in Post-Myocardial Infarction Patients Treated by β-Blockers: A Secondary Analysis of the ABYSS Trial.
Alternative Splicing of TPM1 Mediated by SRPK3 Drives Cardiac Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction
Incremental Prognostic Value of Subendocardial Myocardial Flow Reserve in Patients With Normal Perfusion
A Genome-First Study of Familial Hypercholesterolemia Comparing African and European Ancestry Individuals
Integrative Molecular Analyses of Inflammatory and Autoimmune Signals in Cardiac Sarcoidosis
Pulsed Field Ablation Versus Sham to Treat Atrial Fibrillation: The PFA-SHAM Randomized Clinical Trial
Hypoxia Upregulation of BACH1 Aggravates Pulmonary Hypertension Through TGFBR2/SMAD Pathways
Lipoprotein(a) Levels, Risk of Cardiovascular Events, and Benefit of Evolocumab: Findings From the VESALIUS-CV Trial
Sam68 Exacerbates Pathologic Cardiac Hypertrophy by Suppressing Cardiomyocyte Glucose Oxidation
Evolocumab in Patients With Prior Percutaneous Coronary Intervention and No Prior Myocardial Infarction: Results From the VESALIUS-CV Trial
Laroprovstat, the First Oral Small-Molecule PCSK9 Inhibitor for the Treatment of Hypercholesterolemia: Results From a Randomized, Single-Blind, Placebo-Controlled Phase 1 Trial in Treatment-Naïve Patients
Determining the Physiological Threshold for Angina (ORBITA-FIRE): A Double-Blind, Randomized, Placebo-Controlled Study.
GPRASP1 Safeguards Endothelial Aspartate Metabolism to Prevent Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction.
JNK2 Is a Stress Integrator Driving Atrial Fibrillation Pathogenesis in Aging via Gut-Heart Crosstalk.
The Natural History of Massive Left Ventricular Hypertrophy in Pediatric Hypertrophic Cardiomyopathy: A Multiregistry Analysis.
Phone-Based Intervention Under Nurse Guidance for Control of Hypertension After Stroke: A Randomized Multicenter Phase 3 Trial in Ghana.
Mir147 Limits the Contribution of Non-Foamy Macrophages to Atherosclerosis.
Cardiovascular-Kidney-Metabolic Syndrome Stages, Echocardiographic Characteristics, and Heart Failure Risk: The Atherosclerosis Risk in Communities Study.
The Fontan Outcomes Network: Findings After 2 Years and 1121 Participants.
Memantine for Premature Atrial Contractions: A Phase 2 Randomized Clinical Trial.
CRLF1 Secreted by Cardiac Fibroblasts Promotes Human Hypertrophic Cardiomyopathy
TRIM28 Is an E3 Ligase of IRP2 Suppressing Ischemia/Reperfusion-Induced Myocardial Ferroptosis.
A Critical Contribution of Cardiac Myofibroblasts in Right Ventricular Failure and the Role of UCP2 SNPs in the Predisposition to RV Decompensation in Pulmonary Arterial Hypertension.
Differences in Disease Trajectory, Comorbidities, and Mortality in Sarcomeric and Nonsarcomeric Hypertrophic Cardiomyopathy.
Aortic and Iliac Calcifications as Predictors of Aortic Dissection, Aneurysm Rupture, and Peripheral Vascular Disease: A Prospective Cohort Study from the DANCAVAS Trials.
Small Extracellular Vesicle External Surface Adiponectin-Mediated Adipocytes/Cardiomyocytes Communication in Diabetic Ischemic Heart Failure.
PAM-VT 2 Study: Long-Term Scar Evolution and Ablation Lesion Assessment by Late Gadolinium Enhancement Cardiac Magnetic Resonance After Ventricular Tachycardia Ablation.
Risk of Heart Failure Hospitalization for GLP-1 Receptor Agonists Versus DPP-4 Inhibitors or SGLT-2 Inhibitors in Patients With Type 2 Diabetes: A Target Trial Emulation.
CCR8 Expression on Regulatory T Cells Reveals Trajectories of Tissue Adaptation and Protects Against Myocardial Infarction-Induced Tissue Damage.
Elevated Pulmonary Artery Wedge Pressure in Group 1 Pulmonary Hypertension.
Prospective Associations of Obesity and Obesity Severity With 9 Cardiovascular Outcomes: The Cross-Cohort Collaboration.
Natural History of Patients With Histologically Proven Acute Eosinophilic Myocarditis.
Defining an Optimal Result of Transcatheter Tricuspid Valve Intervention: Results From the Tri-QOL Study
Systemic Embolic Events in Atrial Fibrillation: An Individual Patient Data Meta-analysis of 71 683 Participants Randomized to NOAC Versus Warfarin.
Association of Pre-Fontan Hemodynamics With Long-Term Outcomes After Fontan Palliation: A Study From the Pediatric Cardiac Care Consortium
CXCR6+ T Cells Drive Immune Checkpoint Inhibitor Myocarditis.
Prognostic Implications of Evolving Universal Definitions of Periprocedural Myocardial Infarction in Patients With Acute Coronary Syndrome.
Inhibition of Annexin A2 Facilitates PHB2-Mediated Mitophagy in Cardiomyocytes to Alleviate Cardiac Injury and Remodeling After Infarction.
Myocardial Recovery With Mechanical Circulatory Support Is Linked to Alternative Splicing and Subcellular Localization of CAMK2D.
Engineered Regulatory T Lymphocytes Promote Infarcted Heart Repair.
Macrophage-Specific E3 Ubiquitin Ligase TRIM31 Reduces Atherosclerotic Plaque Formation by Targeting LOX-1.
IMPROVE-DiCE, a 2-Part, Open-Label, Phase 2a Trial Evaluating the Safety and Effectiveness of Ninerafaxstat in Patients With Cardiometabolic Syndromes.
Endothelial Transcription Factor EB Protects Against Doxorubicin-Induced Endothelial Toxicity and Cardiac Dysfunction.
Bradycardia in Athletes: Prevalence, Mechanisms, and Risks.
S-Nitrosylation of Pyruvate Kinase Isoform 2 Drives Cardiac Fibrosis by Promoting Mitochondrial Fission.
Safety, Utility, and Outcomes of Procainamide Challenge for the Diagnosis and Exclusion of Brugada Syndrome.
Oxidized Phospholipids, Lipoprotein(a), and Cardiovascular Outcomes After Acute Coronary Syndrome
Leveraging a Genetic Proxy to Investigate the Effects of Lifelong Cardiac Sodium Channel Blockade.
OxLDL-Targeted Chimeric Antigen Receptor T Regulatory Cells Reduce Atherosclerotic Plaque Development.
Sacubitril-Valsartan for the Prevention of Anthracycline Cardiotoxicity in Patients With Elevated Cardiac Troponin I Concentration During Chemotherapy: A Double-Blind Randomized Placebo-Controlled Clinical Trial: The SARAH Trial.
Quantitative Identification of High-Risk Tricuspid Regurgitation by Cardiac Magnetic Resonance.
Cardiac Allograft Vasculopathy Inhibition with Alirocumab: The CAVIAR Trial.
Dapagliflozin to Reduce Early Recurrence After Catheter Ablation for Atrial Fibrillation: The DARE-AF Randomized Clinical Trial.
Incidence, Risk Factors, and Outcomes in Stressor-Associated Atrial Fibrillation: Insights from the VITAL-AF Trial
Deep Learning–Based Continuous QT Monitoring to Identify High-Risk Prolongation Events After Class III Antiarrhythmic Initiation
Triple Versus Dual Lipid-Lowering Therapy in Acute Coronary Syndrome: The ES-BempeDACS Randomized Clinical Trial.
Prognostic Value of Exercise Right Ventricular-Pulmonary Arterial Coupling in Primary Mitral Regurgitation.
Efficacy and Safety of Very Low Achieved LDL-Cholesterol in Patients with Prior Ischemic Stroke.
Combined Adaptive Immune Mechanisms Mediate Cardiac Injury After COVID-19 Vaccination.
Geometric Features of Ventricular Tachycardia Corridors in Patients With Ischemic Cardiomyopathy.
IRF5 siRNA Nanoimmunotherapy: Restoring Macrophage Efferocytosis in Atherosclerosis.
Nuclear eNOS Interacts With and S-Nitrosates ADAR1 to Modulate Type I Interferon Signaling and Endothelial Function.
The Role of the Collateral Circulation in Stable Angina: An Invasive Placebo-Controlled Study.
Short-Term Anticoagulation versus Dual Antiplatelet Therapy for Preventing Device Thrombosis Following Left Atrial Appendage Closure: The ANDES Randomized Clinical Trial.
Heart Stress and Blood Pressure Management in Older Adults: Post Hoc Analysis of the ASPREE Trial.
Bailout Intracranial Angioplasty or Stenting After Thrombectomy for Acute Large Vessel Occlusion: 1-Year Outcomes of ANGEL-REBOOT.
ALDH2/eIF3E Interaction Modulates Protein Translation Critical for Cardiomyocyte Ferroptosis in Acute Myocardial Ischemia Injury.
Hypercontractility and Oxidative Stress Drive Creatine Kinase Dysfunction in Hypertrophic Cardiomyopathy.
Transcatheter Closure of Patent Foramen Ovale With a Novel Biodegradable Device: A Prospective, Multicenter, Randomized Controlled Clinical Trial.
High-Voltage Focal Pulsed Field Ablation to Treat Scar-Related Ventricular Tachycardia: The First-in-Human VCAS Trial.
Single-Cell Splicing Isoform Atlas of the Adult Human Heart and Heart Failure.
Clinical and Prognostic Significance of Anomalous Origin of a Coronary Artery in Adults.
Screening-Detected Atrial Fibrillation and Cardiovascular Outcomes in Working-Age Adults.
PYGM Protects Against Myocardial Infarction by Enhancing Glycogenolysis and Facilitating Autophagic Flux.
Fibroblast-Specific Loss of TGF-β Signaling Mediates Lipomatous Metaplasia in the Infarcted Heart.
Role of A2AR-D2R Dimerization and D2R-Biased Signaling in PDE10A-Mediated Cardiac Hypertrophy.
TAX1BP3 Is a SUMOylated Nucleocytoplasmic Shuttling Protein and Protects Against Vascular Neointimal Hyperplasia.
Drug-Eluting Resorbable Scaffold Versus Balloon Angioplasty for Below-the-Knee Peripheral Artery Disease: 2-Year Results From the LIFE-BTK Trial.
Health Status Outcomes With Percutaneous Coronary Intervention and Coronary Artery Bypass Grafting in ISCHEMIA
Characterization and Application of Novel Exercise Recovery Patterns That Reflect Cardiac Performance: A Substudy of the SEQUOIA-HCM Trial.
Clinical Presentation and Outcomes After Surgery for Mitral Regurgitation: Real-World Insights From the MITRACURE International Registry.
Dapagliflozin in Patients Hospitalized for Heart Failure: Primary Results of the DAPA ACT HF-TIMI 68 Randomized Clinical Trial and Meta-Analysis of Sodium-Glucose Cotransporter-2 Inhibitors in Patients Hospitalized for Heart Failure.
Biomarker-based ABC-AF Risk Scores for Personalized Treatment to Reduce Stroke or Death in Atrial Fibrillation - a Registry-based Multicenter Randomized Controlled Study.
Sacubitril-Valsartan and Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy: The PRADA II Randomized Clinical Trial.
Ivabradine in Patients Undergoing Noncardiac Surgery: a Randomized Controlled Trial.
Three-Year-Follow-Up of the NOTION-2 Trial: TAVR Versus SAVR to Treat Younger Low-Risk Patients with Tricuspid or Bicuspid Aortic Stenosis.
Redefining the Genetic Architecture of Hypertrophic Cardiomyopathy: Role of Intermediate Effect Variants.
Peri-interventional Anesthesia Strategies for Transcatheter Aortic Valve Implantation: A Multicenter, Randomized, Controlled, Non-inferiority Trial.
Prognostic Role of Myocarditis-Like Episodes and Their Treatment in Patients With Pathogenic Desmoplakin Variants.
Transcatheter Aortic Valve Replacement With Balloon- Versus Self-Expandable Bioprostheses for the Treatment of Bicuspid Aortic Valve Stenosis
Human Single-Nucleus RNA Sequencing Identifies CD47 as a Therapeutic Target for Doxorubicin-Induced Cardiomyopathy.
Long-Term Outcomes of Early Surgery Versus Conventional Treatment for Asymptomatic Severe Mitral Regurgitation: A Propensity Analysis.
TBX5 and CHD4 Coordinately Activate Atrial Cardiomyocyte Genes to Maintain Cardiac Rhythm Homeostasis.
G Protein-Coupled Receptor Kinase 3 Exacerbates Diabetic Heart Injuries Through Direct Phosphorylation of Cannabinoid Receptor 2 in Humans and Mice.
Ponatinib, But Not the New Abl-Kinase Inhibitor Asciminib, Activates Platelets, Leukocytes, and Endothelial Cell TNF Signaling to Induce Atherosclerotic Plaque Inflammation, Myocardial Infarction, and Stroke.
Hypertriglyceridemia as a Key Contributor to Abdominal Aortic Aneurysm Development and Rupture: Insights From Genetic and Experimental Models.
Single-Cell Multi-Omics Identifies Specialized Cytotoxic and Migratory CD8+ Effector T Cells in Acute Myocarditis.
Evaluation of Lipoprotein(a) as a Prognostic Marker of Extracoronary Atherosclerotic Vascular Disease Progression.
Junctophilin-2 Regulates Store-Operated Calcium Entry to Drive Cardiac Fibroblast Activation, Fibrotic Repair, and Angiogenesis After Myocardial Infarction.
Association of Statin Treatment and Dose With the Clinical Course of Small Abdominal Aortic Aneurysms in Men: A 5-Year Prospective Cohort Study From 2 Population-Based Screening Trials.
The Impact of Fontan Circulatory Failure on Heart Transplant Survival: A 20-Center Retrospective Cohort Study.
8
Metformin on the Presence of COVID-19 Symptoms 6 Months after Infection: The ACTIV-6 Randomized Clinical Trial
Outcomes associated with empiric azithromycin use among patients hospitalized with non-severe community-acquired pneumonia: emulation of a target trial
<atl>iLegionella/i Pneumonia in the Modern Era: Clinical Features and Predictors of Mortality</atl>
Associations between antibiotic use and outcomes in patients hospitalized with community-acquired pneumonia and positive respiratory viral assays
Risk Assessment in a Global CVD Prevention Cohort of People with HIV by PCE, PREVENT, and SCORE2
Cardiac Manifestations of iMycoplasma pneumoniae/i Infections: A Cohort Study 2007–2024
Win Ratio Aligns With and Enhances Interpretation of REPRIEVE's Primary Findings
Target Trial Emulation of Empiric Antibiotics on Clinical Outcomes in Moderately Immunocompromised Patients Hospitalized with Pneumonia
15
International Validation of Temperature-Trajectory Sepsis Subphenotypes With Longitudinal Immune and Coagulation Patterns and Its Implications for Immunoglobulin Therapy.
Epidemiology and Outcomes Among Adults With Severe Community-Acquired Bacterial Pneumonia Hospitalized in the United States, 2021–2024
Brain and Muscle ARNT-Like 1 Ameliorates Sepsis-Induced Acute Lung Injury by Orchestrating Endoplasmic Reticulum-Phagy and Mitochondrial Metabolism
Cardiovascular Subphenotypes in Sepsis
Prognostic Value of Lung Injury Biomarkers in Patients Hospitalized With COVID-19 Without Respiratory Failure at Admission
Effects of High-Flow Nasal Cannula and Helmet Continuous Positive Airway Pressure in Acute Hypoxemic Respiratory Failure.
Effect of Neostigmine on Attenuation of Proinflammatory Cytokines When Given as an Adjuvant Therapy in Septic Shock: A Randomized Control Trial.
Preoperative and Intraoperative Risk Factors for Postoperative Pneumonia After Cardiac Surgery: An Ancillary Study of the STERNOCAT (Catheter Outcomes With Sternotomy Cardiac Operated) Randomized Trial and a Systematic Review With Meta-Analysis.
Association Between Noninvasive Positive Pressure Ventilation Use and Clinical Outcomes During a Severe Asthma Exacerbation: A Cohort Study.
The Impact of High-Flow Nasal Cannula Therapy on Diaphragmatic Function Assessed by Ultrasound: A Pilot Clinical Study.
Physiological Effects of High-Flow Nasal Oxygen Compared With Conventional Oxygen Therapy: A Randomized Trial in Postextubation Patients.
Patient Backgrounds and Outcomes of Mechanically Ventilated Children Treated in ICUs Versus General Wards in Japan: A Retrospective Cohort Study Using a National Inpatient Database.
Multimodal Noninvasive Monitoring of Arterial Pressure: Do Limitations of Finger Cuff Monitoring Compromise Upper Arm Measurements? A Post Hoc Analysis of Two Prospective Cohorts.
Decreased Clearance of Low-Density Lipoprotein Cholesterol is Causally Associate With Increased Mortality of Septic Shock.
Association Between Initial Left Ventricular Systolic Dysfunction and Clinical Outcome in Sepsis: A Multicenter Cohort Study.
2
Sympathetic innervation maintains the murine quiescent skeletal muscle stem cell pool via perivascular-derived Angpt1
Disruption of E-cadherin in the airway led to dysplastic stressed cells and asthma-like phenotypes
13
Evolocumab in Patients With High-Risk Diabetes: Results From the VESALIUS-CV Trial.
Clinical Risk Factors Differ by Sex for Kidney Complications but Not Retinopathy in Type 1 Diabetes: The Pittsburgh Epidemiology of Diabetes Complications Cohort
Precision prescribing of SGLT2-inhibitors in people with type 2 diabetes for primary prevention of heart failure: model development and validation study
Effects of Sodium/Glucose Cotransporter-2 Inhibitor Use on Mortality, Amputation, and Healing in Patients With Diabetic Foot Ulcer.
Metabolic Factors Modulating the Connection Between Diabetes and Pulmonary Alterations.
Socioeconomic Factors and Initiation of Semaglutide or Tirzepatide Among Medicare Beneficiaries With Type 2 Diabetes.
Coronary Stent Failure in Patients With Diabetes: A Nationwide Observational Study From SWEDEHEART.
Incidence of Type 2 Diabetes With Verapamil Compared With Other Calcium Channel Blockers.
Screening Natriuretic Peptide Levels Predicts Heart Failure and Death in Individuals With Type 1 and Type 2 Diabetes Without Known Heart Failure.
Familial Hypercholesterolemia in Pediatric Patients With Type 1 Diabetes: Double Challenge for Diagnosis and Treatment.
Differences in Prevalence and Incidence of Electrocardiogram Abnormalities and Cardiovascular Autonomic Neuropathy Among Randomized Glucose-Lowering Treatments in Early Type 2 Diabetes: The Glycemia Reduction Approaches in Diabetes (GRADE) Cohort.
Racial Inequity in Prescription of Semaglutide Among Eligible People With HIV
International Variation in Case Fatality After Major Coronary or Cerebrovascular Events in Individuals With Type 2 Diabetes: Evidence From ADVANCE, TECOS, and EXSCEL.
1
A New Mouse Model for Ozone Health Effects Research
13
The Oxidative Potential of PM2.5 Outperforms Its Mass Concentration in Association with Childhood Sleep Disorders: Evidence from a Large-Scale Study in China
A longitudinal cohort study of damp and mouldy housing and children's respiratory health in Bradford, UK
C3a-C3ar1 axis mediates macrophage M1 polarization to drive silicosis inflammation and fibrosis
U-shaped Association Between Outdoor Artificial Light at Night Exposure and Metabolic Syndrome in Chinese Youth: Findings from a Nationally Representative Study
TRPA1 mediates ozone-induced murine model of COPD through the Wnt5a/GSK-3β/β-catenin pathway
Co-exposure to multiple fine particulate matter constituents and adults obstructive sleep apnoea (OSA) in Southern China
Benzo(a)pyrene exposure aggravates airway remodeling in asthma by activating AhR-GDF15 pathway in epithelial cells
Abundance and environmental health risk of airborne pathogenic fungi in residential environments surrounding rice mills
Global distribution and evolutionary trends of the PM2.5 health burden predicted with a Geographically Neural Network Weighted Regression model
Web application for particulate matter deposition quantifier: an easy and accessible tool for assessment while exercising
Protective Role of DsbA-L in COPD: Alleviating ER Stress-Induced Apoptosis Through AMPK Activation
Associations of environmental toxicant exposure with adult sleep problems and the mediating roles of inflammation
Silica-induced innate immune activation drives macrophage pyroptosis and lung inflammation through glycolytic reprogramming
20
Diesel Exhaust Particles Act as an Environmental Trigger of Hypersensitivity Pneumonitis–like Immune Responses in the Lung
Exposure to Coal-fired Power Plant Emissions, Unconventional Natural Gas Development, and Salivary miRNA Profiles and Asthma in Children
Beyond Quantitative Indicators: Comprehensive Characterization of Indoor Fungal Contamination in Portuguese Elementary Schools
Lifetime urban exposure, socioeconomic position and respiratory health among adolescents
Endoplasmic reticulum stress mediates oxidative stress-driven endothelial impairment and atherogenesis induced by sodium perfluorononenoxybenzene sulfonate exposure
Impacts from Sector-Specific Energy Policies on Mortality Co-Benefits and Socioeconomic Disparities Across Three Midwestern States in the Year 2050
The association between outdoor noise and temperature exposure with incident type 2 diabetes, and mediation by sleep and body mass index: A multi-cohort analysis
Trajectories of Meteorological and Air Pollution Exposures during pregnancy and risk of Childhood Asthma: A Population-Based Cohort Study
Household Environmental Characteristics Influence House Dust Metagenome
Evaluating heterogeneity in the impact of the reformulated gasoline program on childhood and young adult lymphoma incidence: A Bayesian causal inference analysis
Mouldy area size and asthma symptom score and control in adults: the CONSTANCES cohort
Health benefits of traffic emissions controls in Melbourne, Australia
Ten-year exposure to household air pollution is associated with obstructive sleep apnoea
Stress modifies pulmonary and inflammatory response to ozone: controlled human exposure study
Toward equitable environmental exposure modeling through convergence of data, open, and citizen sciences: an example of air pollution exposure modeling amidst increasing wildfire smoke.
Towards real life exposure: nasal epithelial cell stimulation with pollen particle aerosols
Interaction between airway inflammation and gut microbiota dysbiosis caused by high temperatures (40 °C) and traffic-PM2.5 in mouse model
Effects of Per- and polyfluoroalkyl substances on atherosclerosis: an evidence-based risk assessment in the context of the TRAEC strategy
Impact of Ambient Ozone Exposure on Cardiac Biomarkers in Heart Failure and the Role of Sodium-glucose Cotransporter-2 Inhibitors: Findings from the TRACER-HF Trial
Environmental justice in France: Analysis of the association between exposure to environmental pollution and social deprivation
14
TROPOMI CO and NO2 as Observational Constraints on the Sources of Air Pollution Inequalities in US Cities
Quantifying Olfactory and Alveolar Deposition of Ultrafine Particles Using Multiscale Modeling: Implications for Brain Exposure
Estimating Reductions in Premature Mortality Attributable to Outdoor Ultrafine Particles with Increasing Prevalence of Electric Vehicles and Other Tailpipe-Related Emission Reduction Scenarios
Bisphenol A and Its Substitutes Show Proatherosclerotic Potential through the Dysregulation of CD36-Driven Cholesterol Homeostasis
Occurrence, Fate, and Transport of Aquatic and Terrestrial Contaminants
Differential Reductions in Total and Compositional PM2.5 Exposure across Socioeconomic and Demographic Groups from Emission Source Mitigation in Canada (2007–2016)
Finer Particulate Matter Exposure Disparities Exist but Vary across Pollution Concentrations
Reflection of Sectoral Emissions on Air Quality, Mortality, and Air Pollution Exposure Inequalities in a Metropolitan Context
Methodological Design Choices Can Affect Air Pollution Exposure Disparity Estimates: A Case Study on California’s Agricultural Sector
Implications of Off-Peak Commercial Deliveries for Air Quality and Environmental Justice
Ozone Exposure (Outdoor–Indoor–Personal) and Mental Health in Young Adults
High-Resolution Assessment of Air Quality, Health, and Equity Co-Benefits of California’s 2022 Scoping Plan for Carbon Neutrality in the South Coast Air Basin
Intracranial Hemorrhage in Zebrafish: An Adverse Outcome Induced by Lovastatin
Environmentally Relevant Levels of Ozone Enhance iKlebsiella pneumoniae/i Pulmonary Colonization and Cross-Organ Translocation
125
Cardiac remodelling and dysfunction in cancer patients receiving cardiotoxic therapies: proteomic and metabolomic profiling
Blood aldosterone concentrations and effects of mineralocorticoid receptor antagonists in heart failure
Cholesterol-lowering therapy from childhood/adolescence and long-term outcomes in familial hypercholesterolaemia: the SAFEHEART study
ACADM-mediated fatty acid β-oxidation pathway in atherosclerosis and abdominal aortic aneurysm
Predicting lifetime cardiovascular risk and benefits of preventive treatment in patients with established atherosclerotic cardiovascular disease: the SMART-REACH2 model
Safety of low lipoprotein(a) levels: the FOURIER trial
Ferroptosis promotes aortic stenosis through 5-lipoxygenase
Standard modifiable risk factors among patients undergoing percutaneous coronary intervention: prevalence and impact
GLI1 activation induced by intermittent hypoxia drives cardiac fibroblast activation via enhanced PKM2-mediated glycolysis
Tetralogy of Fallot: electrophysiology-guided surgical ablation during pulmonary valve replacement
Right aortic arch and double arch assessed by prenatal echocardiography: a population-based study
Arrhythmias, dementia risk, and neurodegeneration: a cohort study
Interleukin-6 and C-reactive protein prognostic value following acute coronary syndrome
Chimeric antigen receptor T-cell therapy and cardiovascular outcomes in US Medicare beneficiaries
Obicetrapib and lipoprotein(a) levels in patients at high cardiovascular risk: a pooled analysis of trials
Outcomes in the BETAMI-DANBLOCK trial compared with a Norwegian nationwide myocardial infarction population
Endurance exercise remodels pulmonary vein sleeve myocytes and promotes a proarrhythmic atrial substrate
Angina with non-obstructive coronary arteries and myocardial bridge: long-term outcomes of surgical unroofing
Intrapericardially injected hydrogel loaded with stromal cell secretome microparticles improves post-infarction myocardial repair in pigs
MTMR4 variants have opposite gene-specific impact on life-threatening arrhythmic risk in type 1 and 2 long QT syndrome
Molecular mechanism leading to human coronary atherosclerosis assessed by proteomic analysis and RNA sequences
Outcomes after a first acute myocardial infarction in patients with or without congenital heart disease
A nurse-coordinated intervention programme vs standard of care after an acute coronary syndrome: the ALLEPRE trial
Cancer and heart failure: prevalence, incidence, and prognosis in Scotland
PCSK9 inhibitor treatment and outcomes in patients with atherosclerotic cardiovascular disease but without prior ischaemic events: an observational study
Cardiac resynchronization therapy with or without atrioventricular node ablation in atrial fibrillation: the CAAN-AF trial
New-onset postoperative atrial fibrillation management and outcomes: the VISION Cardiac Surgery cohort
Stroke and systemic embolism following atrial fibrillation ablation: the EMBOL-AF Global Registry
Atrial fibrillation density as a biomarker for ischaemic stroke risk prediction
Sex differences in cardiovascular–kidney–metabolic syndrome: the FINE-HEART pooled analysis
Risk prediction in patients with heart failure with preserved ejection fraction: the LIFE-Preserved model
Prediction of incident heart failure in established atherosclerotic cardiovascular disease: the SMART2-HF model
Artificial intelligence–based quantification of breast arterial calcifications to predict cardiovascular morbidity and mortality
Laminopathies: natural history and risk prediction of heart failure
Aficamten in symptomatic obstructive hypertrophic cardiomyopathy: the FOREST-HCM long-term study
Nuclear AGO2 exacerbates heart failure with preserved ejection fraction through myocardial ketogenesis
SLC4A3-related short QT syndrome assessed in human induced pluripotent stem cell-derived cardiomyocytes: mechanisms of ventricular arrhythmia and sudden cardiac death
Carotid plaque macrophage burden and inflammatory lipid-associated macrophage markers predict secondary major adverse cardiovascular events after endarterectomy
Switching from warfarin to direct oral anticoagulants in frail elderly Asian patients with atrial fibrillation: a Korean nationwide study
Pelacarsen and lipoprotein(a) apheresis in secondary prevention: the Lp(a)FRONTIERS APHERESIS trial
Aspirin use, lipoprotein(a), and calcific aortic valve disease: the Multi-ethnic Study of Atherosclerosis
Arrhythmias in congenitally corrected transposition of the great arteries: an international study
Macrophage SBK2 suppresses inflammation and atherosclerosis by NLRP3 phosphorylation
Spatial transcriptomics reveals a key role of fibroblast-like vascular smooth muscle cells in human atherosclerotic cell crosstalk and stability
Soluble ST2 drives fulminant myocarditis progression via the IGF2R–YY1 mitochondrial axis
Macrophage-specific circular RNA circHIPK2, inflammation, and fibrosis after myocardial infarction
Computed tomography-guided vs conventional catheter ablation for ventricular tachycardia: the InEurHeart trial
Heart failure in the Portuguese population aged ≥50 years: prevalence and phenotypes in the PORTHOS study
Subvalvular aortic stenosis in adults: clinical course and long-term outcomes
Frozen elephant trunk for acute type A aortic dissection: long-term outcomes over two decades
Heart failure with preserved ejection fraction in adults with congenital heart disease
Peri-operative myocardial infarction/injury after non-cardiac surgery: association between cardiologist evaluation and outcomes
Peripheral autonomic dysregulation in response to standing: a new form associated with cardiovascular disease, mobility reduction, and cognitive alterations
Risk-weighted apoB: a novel summary metric outperforming traditional lipid biomarkers in predicting coronary heart disease
Foundation models for electrocardiogram interpretation: clinical implications
Pulsed field vs radiofrequency ablation for paroxysmal atrial fibrillation: the BEAT PAROX-AF trial
Anthracycline cardiotoxicity: role of metabolic vulnerability induced by cardiac pressure overload
Left bundle branch vs biventricular pacing: mechanistic insights from a canine model
Congenital heart defects: familial recurrence patterns in Sweden
Complete revascularization timing in ST-segment elevation myocardial infarction and multivessel disease with heart failure: the OPTION–STEMI trial
Major arrhythmias in non-dilated left ventricular cardiomyopathy: a novel prediction score
Adults with Fontan circulation: prognostic value of exercise pulmonary vascular resistance index
The junctional protein associated with coronary artery disease predicts adverse cardiovascular events in patients with acute coronary syndromes at high residual risk
Physiology vs angiography-guided percutaneous coronary intervention in transcatheter aortic valve implantation: the FAITAVI trial
Mitral transcatheter edge-to-edge repair and outcomes according to baseline health status: the RESHAPE-HF2 trial
Catecholaminergic polymorphic ventricular tachycardia mediated by ryanodine receptor 2: a validated risk stratification
Atherosclerotic progression at sites of low shear stress is attenuated by myeloid-PlexinD1 deficiency through suppression of classical macrophage polarization
Combined clinical, metabolomic, and polygenic scores for cardiovascular risk prediction
Sex-specific cardiac ageing and sympathetic compensation: a translational study
Long forms of cardiac troponin T for myocardial infarction diagnosis: the SuperTROPO study
Digital profile of children’s hearts: automated echocardiogram strain analysis facilitates earlier detection of cardiac dysfunction
Diabetes and sudden cardiac death: a Danish nationwide study
Oestrogen-related receptor γ in sepsis-induced cardiomyopathy: role of cardiomyocyte subtype conversion
Osimertinib induces reversible cardiac dysfunction through the GATA4-MYLK3-MYL2 axis
The macrophage-derived motor protein KIF13B enhances MERTK-mediated efferocytosis and prevents atherosclerosis in mice
Women with chronic coronary artery disease: long-term outcomes after percutaneous coronary intervention vs coronary artery bypass grafting
Artificial intelligence-enhanced electrocardiography to predict regurgitant valvular heart diseases: an international study
Temporal trends in the use of oral anticoagulants and clinical outcomes in older, elderly, and very elderly patients with atrial fibrillation: a Danish nationwide study
Enhanced antigen presentation by macrophages promotes human atherosclerosis progression: therapeutic implications
Endotypes of angina with non-obstructive coronary arteries: a prospective multicentre study
High-sensitivity cardiac troponin I and risk of dementia: the 25-year longitudinal Whitehall II study
Genetic evaluation of early-onset atrial fibrillation: impact on patient management
Dementia risk across blood pressure categories: a South Korean nationwide study
Early outcomes of children with univentricular circulation undergoing Fontan surgery: the EuroFontan registry
Outcomes of moderate mixed aortic valve stenosis and regurgitation
Atrial cardiomyopathy: markers and outcomes
Left ventricular geometry, brain architecture, and cognition: an observational study
Blood pressure, plasma proteins, and cardiovascular diseases: a network Mendelian randomization and observational study
Antihypertensive treatment in young adults and cardiovascular risk: a population-based cohort study
Sex differences in atrial fibrillation-related atrial remodelling assessed by electroanatomic mapping and biopsy
EP4/ANXA2 axis in pulmonary arterial hypertension: therapeutic implications
Drug-coated vs non-drug-coated devices for femoropopliteal artery interventions: long-term outcomes of the SAFE-PAD study
Transcriptomic biomarkers related to cardiac disease in childhood cancer survivors: a case-control study
Left bundle branch area pacing vs right ventricular pacing for atrioventricular block: the MELOS RELOADED study
Early antiplatelet treatment for minor stroke following thrombolysis: the EAST trial
Endothelial plasticity in atrial fibrosis by integrating single-cell sequencing and genetic lineage tracing
Fulminant myocarditis: outcome predictors in an international cohort study
Cytosolic calcium handling signature: integration with clinical predictors enhances prediction of post-operative atrial fibrillation
Sex-specific outcomes after transcatheter or surgical treatment of aortic valve stenosis: the DEDICATE-DZHK6 trial
Surgical left atrial appendage occlusion in valvular heart disease without atrial fibrillation: the OPINION trial
Temporal modulation of antiplatelet therapy in high-risk patients undergoing complex percutaneous coronary intervention: the TAILORED-CHIP randomized clinical trial
Arrhythmic genotypes in dilated cardiomyopathy and risk of advanced heart failure
C-reactive protein and cardiovascular risk among women with no standard modifiable risk factors: evaluating the ‘SMuRF-less but inflamed’
Surgical myectomy for hypertrophic cardiomyopathy: procedural volume and outcomes
Atrial fibrillation and atherosclerosis cause different vascular brain lesions on magnetic resonance imaging
iLIPA/i, a risk locus for coronary artery disease: decoding the variant-to-function relationship
Coronary function testing vs angiography alone to guide treatment of angina with non-obstructive coronary arteries: the ILIAS ANOCA trial
Withdrawal of heart failure therapy after atrial fibrillation rhythm control with ejection fraction normalization: the WITHDRAW-AF trial
Aspirin, cardiovascular events, and major bleeding in older adults: extended follow-up of the ASPREE trial
Titin-related familial dilated cardiomyopathy: factors associated with disease onset
Low-density lipoprotein cholesterol and cardiovascular risk in the absence of calcifications on computed tomography: the Western Denmark Heart Registry
Cardiovascular benefit of continuous positive airway pressure according to high-risk obstructive sleep apnoea: a multi-trial analysis
Heparin administration at first medical contact vs immediately before primary percutaneous coronary intervention: the HELP-PCI trial
Kidney function trajectories before and after hospitalization for heart failure with reduced ejection fraction
Excessive glycosylation drives thoracic aortic aneurysm formation through integrated stress response
Cryoballoon vs radiofrequency ablation in persistent atrial fibrillation: the CRRF-PeAF trial
Mind the gaps: blood pressure variability and its impact on health
ApoB and Lp(a): core measures to assess cardiovascular risk
Colchicine for secondary prevention of vascular events: a meta-analysis of trials
Long-term trials of colchicine for secondary prevention of vascular events: a meta-analysis
Cumulative exposure to atherogenic lipoprotein particles in young adults and subsequent incident atherosclerotic cardiovascular disease
Radial vs femoral access for percutaneous coronary intervention: temporal trends and outcomes in the USA
First myocardial infarction: risk factors, symptoms, and medical therapy
Long QT syndrome in children and adolescents: risk factors and outcomes in a large German cohort
Natriuretic targets in acute heart failure with volume overload: are we misguided?
1
Mice carrying the homologous human shelterin POT1-L259S mutation linked to pulmonary fibrosis show a telomerase deficiency-like phenotype with telomere shortening with increasing mouse generations
1
Regeneration alters open chromatin and cis-regulatory landscape of erythroid precursors
1
Distinctive hemodynamic phenotype in Fontan-type circulation patients with distal esophageal varices.
1
Ovarian function compromise in pediatric beta-thalassemia major: a consequence of iron overload-induced mitochondrial and fibrotic damage
2
Influenza hijacks myeloid cells to inflict type-I interferon-fueled damage in the heart
Epigenetic silencing of interleukin-10 by host-derived oxidized phospholipids supports a lethal inflammatory response to infections
5
Ten- and thirty-year cardiovascular disease risks using PREVENT equation in Koreans from 2001 to 2021
Life-course trajectories of cardiovascular disease risk factors in rural India: Andhra Pradesh Children and Parents Study (APCAPS) 2003–2023
Comorbidity of asthma and attention deficit hyperactivity disorder in childhood: causal, shared early-life risk factors, or shared genetic liability?
A cohort study of forced vital capacity, airway obstruction, and survival in the multinational Burden of Obstructive Lung Disease study
Human genetics suggests differing causal pathways from HMGCR inhibition to coronary artery disease and type 2 diabetes
15
Reassessing BMI thresholds for obesity: a population-based study in Turkish adults
Linking circulating chemerin and adiponectin to lipoprotein subclasses measured by H-NMR spectroscopy in 3199 participants from the study of health in Pomerania
Unmasking the role of hypertension in atherosclerosis among patients with obesity: a cardiometabolic dysfunction perspective
Circulating lipid subfractions and the risk of longitudinal adiposity progression: findings from the China Kadoorie Biobank
Beyond mean and maximum CO₂: introducing hypercapnic burden as a marker of sleep-related hypoventilation
Obesity prevalence: comparison of traditional and new classification approaches in a Swiss population-based study (2005–2024)
Age-dependent obesity paradox in acute myocardial infarction prognosis: a cohort study of body mass index and recurrent myocardial infarction
Adherence to positive airway pressure therapy and healthcare resource utilization and costs among patients with obstructive sleep apnea and obesity
Peak oxygen consumption as a modifier of the obesity paradox in patients with obesity with heart failure with reduced ejection fraction
Is hyperdynamic circulation a hallmark of obesity?
Cardiovascular risk factors associated with BMI and metabolic health phenotypes based on measures of coagulation factors
Impact of preoperative body mass index on postoperative outcomes in infective endocarditis: a multicenter analysis of 4801 consecutive patients
Life-long body mass index trajectories and cardiometabolic biomarkers-the Danish diet, cancer, and health-next generations cohort
Modelling the direct and indirect associations between anthropometric and behavioural factors when predicting atherogenic risk index (TC/HDL-C) ratio
Which adiposity marker is most strongly associated with all‑cause and cause‑specific mortality? a prospective study of 158,699 Mexican adults
9
Multilevel Stewardship Intervention for Use of Anticoagulation-Antiplatelet Therapy.
Life Expectancy in Chronic Obstructive Pulmonary Disease.
Comparative Effectiveness and Safety of LAMA-LABA Inhalers in Chronic Obstructive Pulmonary Disease
Produce Prescription Subsidy for Patients With Diabetes
SGLT2 Inhibitors vs GLP-1 Receptor Agonists for Kidney Outcomes in Individuals With Type 2 Diabetes
Liraglutide in Acute Minor Ischemic Stroke or High-Risk Transient Ischemic Attack With Type 2 Diabetes
Food Insecurity Interventions to Improve Blood Pressure
Mobile Integrated Health vs a Transitions of Care Coordinator for Patients Discharged After Heart Failure
Metformin and Time to Sustained Recovery in Adults With COVID-19
4
Valved Holding Chambers in Young Children With Acute Wheezing
Change in Weight Status From Childhood to Young Adulthood and Risk of Adult Coronary Heart Disease
Global Prevalence of Hypertension in Children and Adolescents Younger Than 19 Years
Inflammatory Pathways in Residual Asthma Exacerbations Among Mepolizumab-Treated Urban Children
1
Z-Drug Use in the First Trimester of Pregnancy and Risk of Congenital Malformations
1
Temporal Trends of Common Cardiac Surgical Procedures at Veterans Affairs Medical Centers
29
Low-Dose Rivaroxaban and Cardiovascular Events in Advanced Kidney Disease: The TRACK Randomized Clinical Trial.
Cryobiopsy vs Forceps for Bronchoscopic Lung Biopsy: The FROSTBITE-2 Randomized Clinical Trial.
Predictors of Long-Term Outcomes in Hypertrophic Cardiomyopathy
Digoxin in Patients With Symptomatic Rheumatic Heart Disease
Tucidinostat Plus R-CHOP vs R-CHOP in MYC/BCL2 Double-Expressor Diffuse Large B-Cell Lymphoma
Real-World Outcomes of Transcatheter Tricuspid Valve Replacement
Cost-Effectiveness of ApoB, Non–HDL-C, and LDL-C Goals for Primary Prevention Lipid-Lowering Therapy
Evolocumab to Reduce First Major Cardiovascular Events in Patients Without Known Significant Atherosclerosis and With Diabetes
Donation After Circulatory Death Heart Transplant Without Preimplant Reanimation Using Rapid Ultraoxygenated Recovery
Cryopreserved vs Liquid-Stored Platelets for the Treatment of Surgical Bleeding
Sacubitril/Valsartan vs Enalapril in Heart Failure Due to Chagas Disease
Levosimendan to Facilitate Weaning From ECMO in Patients With Severe Cardiogenic Shock
Efficacy and Safety of Oral PCSK9 Inhibitor Enlicitide in Adults With Heterozygous Familial Hypercholesterolemia
Coronary Computed Tomography Angiography in Prediction of First Coronary Events
Familial Hypercholesterolemia Screening in Childhood and Early Adulthood
Metformin to Improve Walking Performance in Lower Extremity Peripheral Artery Disease
SGLT2 Inhibitors and Kidney Outcomes by Glomerular Filtration Rate and Albuminuria
Effects of Sodium Glucose Cotransporter 2 Inhibitors by Diabetes Status and Level of Albuminuria
Bioresorbable vs Metallic Occluders for Transcatheter Atrial Septal Defect Closure
Individualized Perioperative Blood Pressure Management in Patients Undergoing Major Abdominal Surgery
Proactive vs Reactive Treatment of Hypotension During Surgery
Long-Term Continuous Monitoring of New-Onset Atrial Fibrillation After Coronary Artery Bypass Grafting
Respiratory Gas Shifts to Delay Asphyxiation in Critical Avalanche Burial
Individualized Prediction of Platelet Transfusion Outcomes in Preterm Infants With Severe Thrombocytopenia
Fractional Flow Reserve–Guided Complete vs Culprit-Only Revascularization in Non–ST-Elevation Myocardial Infarction and Multivessel Disease
Long-Term Anticoagulation Discontinuation After Catheter Ablation for Atrial Fibrillation
Remote Screening for Asymptomatic Atrial Fibrillation
Stapokibart for Severe Uncontrolled Chronic Rhinosinusitis With Nasal Polyps
Impact of the MISSION Act on Quality and Outcomes of Major Cardiovascular Procedures Among Veterans
31
Intracellular lactic acidosis reprograms glycolysis and mitochondrial anaplerosis in cancer cells
The pentose phosphate pathway contributes to excess lactate production in radiation-induced fibroblast to myofibroblast transdifferentiation
Functional Evaluation of TRPC6 Missense Variants in Cancer Patients via Molecular Docking Analysis Compared with Patch Clamp Electrophysiology
Impact of salt concentration and free magnesium on human beta-cardiac myosin reveal important details about the conserved mechanochemical mechanism
Fortilin binds and stabilizes MEF2C, activates it through phosphorylation, and drives transcription of the cell structural and survival protein CTNNA3
Cell type-specific control of cardiometabolic disease by the dileucine motif of the LDL receptor-related protein LRP1
Neuroprotective Role of Nrf2 Activation Against ER Stress–Mediated Apoptosis in Obstructive Sleep Apnea
Rhinovirus Infection Promotes Suppression of Sphingosine and Enhanced Bacterial Infection in Cystic Fibrosis Airways
Phosphorylation of inner core heptose is a major determinant of bacterial surface lipopolysaccharide recognition by the innate immune protein hSP-D
Divergent pathways of Surfactant Protein C maturation for disease-associated isoforms
ARF6 controls VSMC phenotypic switching upon lipid stimulation to promote inflammatory signaling contributing to the progression of atherosclerosis
Cantu Syndrome-Associated SUR2[H60Y] Mutation Confers Selective Gain-of-Function on Kir6.1 ATP-Sensitive Potassium Channels
Discovery of small molecule modulators of the thin filament that alter the contractile profile in a hypertrophic cardiomyopathy engineered tissue model
Thermodynamics and selection of the plasminogen activator inhibitor-1 latency transition
The histone methyltransferase MLL1 complex inhibits expression of fetal hemoglobin
Farnesyl Pyrophosphate Synthase Promotes Restenosis After Vascular Injury by Activating Small G Proteins
MYBPC3 N-terminal missense mutations linked to hypertrophic cardiomyopathy strengthen actin binding and enhance residue mobility
Loss of O-GlcNAcylation in cardiac myocytes triggers the integrated stress response, contributing to heart
Structural Insights into Hormone Recognition and G-Protein Coupling of the Urotensin-II Receptor
S2Tag, a novel affinity tag for the capture and immobilization of coiled-coil proteins: Application to the study of human β-cardiac myosin
Identification and rescue of congenital hyperinsulinism-associated ABCC8 mutations that impair KATP channel trafficking
Nitric oxide regulates cytochrome P450 2D6 and 3A4 activity via concentration-dependent modulation of heme loading
Gut microbiota–derived metabolite trimethylamine N-oxide alters the host epigenome through inhibition of S-adenosylhomocysteine hydrolase
Suppression of SREBP by a transmembrane protein mutated in cardiomyopathy
Platelet Jak2 deficiency accelerates atherosclerosis with increased inflammatory response
TET2 has endothelial-specific roles in interferon responses that are dysregulated by hyperglycaemia in vitro and in vivo
Hemoglobin β-F41K: a recombinant oxygen carrier prototype engineered for enhanced heme retention, stability, and optimal oxygenation properties
Hypoxia promotes the generation of a versican-rich extracellular matrix by human coronary artery endothelial cells
Inflamed endothelial cells express S1PR1 inhibitor CD69 to induce vascular leak
The metastasis-associated protein MTA3 promotes cardiac repair by inhibiting the fibroblast to myofibroblast transition during fibrosis
Circular RNA-OGDH promotes PANoptosis in diabetic cardiomyopathy: A novel mechanistic insight
1
Impacts of major floods on new human respiratory health symptoms in indoor environments
4
Alcohol and Steatotic Liver Disease Exhibit Divergent Associations with High Plasma Small Dense LDL-C Concentration
Comprehensive Analysis of Disease Spectrum and Mortality in Sanjad-Sakati Syndrome: An International Rare Disease Registry Study
Ovarian reserve and endothelial health in healthy reproductive-age women
HMGCR and rosuvastatin regulates GLP-1 secretion and expression – a translational study
31
AAV-mediated long-term TBX18 expression causes cardiac fibrosis and fails to induce pacemaker activity in rodents
Selective expansion of cardiac macrophage subtypes distinguishes their functional roles in disease and homeostasis
Lymphatic dysfunction and ZFP36 deficiency contribute to myxomatous valve degeneration in Marfan Syndrome mice
Homozygous SGCB splice-site variant causes isolated dilated cardiomyopathy through sarcoglycan complex destabilization in East Asians
Pulmonary Arterial Hypertension Induces a Metabolic and Inflammatory Hepatopathy
Meflin confers antifibrotic properties to intestinal fibroblasts in inflammatory bowel disease
Unrestrained fatty acid oxidation triggers heart failure in mice via cardiolipin loss and mitochondrial dysfunction
Macropinocytosis inhibition attenuates profibrotic responses in lung fibroblasts and pulmonary fibrosis models
Physiological MplW514L expression in hematopoietic stem cell causes an essential thrombocythemia and progressive myelofibrosis
Lipoprotein(a)-Associated Proteomic Signature Predicts Cardiovascular Disease in Young Adults
Therapeutic potential of synergistic mucociliary clearance for cystic fibrosis airways by combined 𝜷-adrenergic + cholinergic agonists
Loss of RPGR disrupts motile cilia and causes primary ciliary dyskinesia by affecting F-actin dynamics
Cilia-independent gas-liquid transport, a third mechanism mediating airway mucus clearance
Fibrosis-memory is mediated by IL-3–producing T cells and drives progression of fibrosis
Tet2-driven clonal hematopoiesis drives aortic aneurysm via macrophage-to-osteoclast-like differentiation
Cardiac radiotherapy-induced epigenetic memory underlies electrophysiologic and metabolic reprogramming
A CD57+ CD8 T cell subset links cytotoxic T cell cytotoxicity to fibrotic lung disease in systemic sclerosis
Carriage of rare APOB variants predisposes to severe steatotic liver disease and hepatocellular carcinoma
ADAMTS7 promotes smooth muscle foam cell expansion in atherosclerosis
Patient-Derived Xenograft Models of Fanconi Anemia-Associated Head and Neck Cancer Identify Personalized Therapeutic Strategies
DLL4+ neutrophils promote Notch1-mediated endothelial PANoptosis to exacerbate acute lung injury in sepsis
Clonal hematopoiesis activates pro-calcific pathways in macrophages and promotes aortic valve stenosis
Selective inhibition of long isoforms of phosphodiesterase 4D mitigates liver fibrosis in mouse models
A positive allosteric modulator of the β1AR with antagonist activity for catecholaminergic polymorphic ventricular tachycardia
CDKL1 variants affecting ciliary formation predispose to thoracic aortic aneurysm and dissection
Allergen-specific mRNA–lipid nanoparticle therapy for prevention and treatment of experimental allergy in mice
Clonal expansion of alveolar fibroblast progeny drives pulmonary fibrosis in mouse models
Myeloid-mesenchymal crosstalk drives ARG1-dependent profibrotic metabolism via ornithine in lung fibrosis
Platelet-specific SLFN14 deletion causes macrothrombocytopenia and platelet dysfunction through dysregulated megakaryocyte and platelet gene expression
Aggressive B-cell lymphomas retain ATR-dependent determinants of T-cell exclusion from the Germinal Center Dark Zone
Caloric Restriction Promotes Resolution of Atherosclerosis in Obese Mice, while Weight Regain Accelerates its Progression
11
High-Dose Methotrexate as CNS Prophylaxis in Ultra High-Risk Large B-Cell Lymphoma: An International Multicenter Analysis
Selinexor Plus Ruxolitinib in Janus Kinase Inhibitor–Naïve Myelofibrosis: Phase III SENTRY Trial
Phased Variant-Supported Circulating Tumor DNA as a Prognostic Biomarker After First-Line Treatment in Large B-Cell Lymphoma: Findings From the DIRECT Study.
Prospective Validation of Circulating Tumor DNA Measurable Residual Disease After First-Line Therapy in Large B-Cell Lymphoma.
BRUIN CLL-313: Randomized Phase III Trial of Pirtobrutinib Versus Bendamustine Plus Rituximab in Untreated Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.
Pirtobrutinib Versus Ibrutinib in Treatment-Naïve and Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.
FLIPI24: A Modern Prognostic Model and Clinical Trial Enrichment Tool for Newly Diagnosed Follicular Lymphoma.
Efficacy and Safety of Glofitamab Plus Polatuzumab Vedotin in Relapsed/Refractory Large B-Cell Lymphoma Including High-Grade B-Cell Lymphoma: Results From a Phase Ib/II Trial.
Mosunetuzumab plus polatuzumab vedotin in transplant-ineligible refractory/relapsed large B-cell lymphoma: primary results of the phase 3 SUNMO trial.
Remission Assessment by Circulating Tumor DNA in Large B-cell Lymphoma.
Health Outcomes Beyond Age 50 Years in Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study.
3
Immune checkpoint inhibitor–induced myocarditis is dependent on CD8 T cell–derived TNF and TNFR2 signaling
Heterozygous human JAK2V617F activates AhR to drive essential thrombocythemia and promote thrombosis
Ciliated cell–derived IL-17D restrains allergic asthma through controlling monocyte recruitment
1
Early portopulmonary hypertension predicts mortality in patients with cirrhosis: insights from the PORTO-DETECT cohort
6
Discriminating Bacterial from Nonbacterial Lower Respiratory Tract Infection within Clinical Subgroups of Hospitalized Adults
Transcriptome analysis of circulating microRNAs associated with Chagas disease susceptibility and chronic Chagas cardiomyopathy severity
Treatment of Pseudomonas by Removal of Cloaking Antibodies: Is Common Polysaccharide Antigen a Factor?
Interferon-gamma production defects characterise immune responses in patients with chronic pulmonary aspergillosis
Effectiveness of 13-Valent Pneumococcal Conjugate Vaccine Against Pneumonia Hospitalization Among Medicare Beneficiaries Aged ≥65 in Long-Term Care
Inflammatory macrophages associate with tissue injury and fibrosis in a mouse model of tuberculosis
1
Mapping the Heart–Brain Continuum beyond Heart Failure: Why Neurology Matters
50
The ultrarapid delayed rectifier potassium current has important functional role in the repolarization reserve of canine and human ventricular muscle
Comparative multimodal calibration of patient‐specific atrial fibrillation models: Impact of imaging and electrophysiology data on arrhythmogenic substrate identification
Extracellular ionic concentration modulates arrhythmias in a simulated population of human ventricular myocytes with long QT syndrome type 3
FURIN induces vascular endothelial cell death and efferocytosis through enzymatic cleavage of thrombospondin‐1
Multiscale mechanistic modelling of heterogeneity in cardiac sub‐cellular calcium handling accounting for variable t‐system density
Beat‐to‐beat variability of ventricular repolarization reveals sex‐specific instability and proarrhythmic risk
When NCX switches sides: Experimental and computational insights into Ca2+ regulation in the heart
Ro5‐4864, a ligand of the mitochondrial translocator protein, protects against heart failure in mice via regulation of the p62‐Keap1‐Nrf2 axis
Altered functional interactions between CFTR disease mutants ΔF508 and G551D and the protein kinase A catalytic subunit
Longer action potential duration in the Purkinje network than in the ventricular myocardium delays retrograde activation of the human His‐Purkinje system
Sex-dependent activation of apamin-sensitive small-conductance Ca2+-activated K+ current by β1-adrenergic stimulation in rabbit ventricles
Sarcolemmal and mitochondrial membrane potentials measured ex vivo and in vivo in the heart by pharmacokinetic modelling of [99mTc]sestamibi
Panoramic voltage‐sensitive optical mapping of contracting hearts using cooperative multiview motion tracking with 12 cameras
Age‐ and sex‐specific modulation of human cardiac electrophysiology by doxorubicin
Intercalated disk structure, tissue heterogeneity and ion channel distribution modulate conduction and local calcium influx
An age‐associated decline in the role of the sarcoplasmic reticulum and associated calcium‐handling proteins sets the pace for sinoatrial node function
Females exhibit greater cardiac volume reductions with expiratory muscle loading during submaximal exercise compared to males
Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron
A model of β‐adrenergic stimulation in human ventricular cells for tissue‐scale simulations of sympathetically modulated tachycardias
Selective RyR2 inhibition reduces arrhythmia susceptibility in human cardiac slices
Anti‐arrhythmic targeting of sympathetic stellate ganglion P2X3 receptors
Computational model of haemodynamics during atrial fibrillation
Evidence for acid‐sensing ion channel 3 (ASIC3) involvement in cough resulting from aspiration of gastric fluid
Structural determinants of re‐entrant drivers in atrial fibrillation: insights from digital twins derived from 3D micrometre‐resolution imaging of human heart
Ventilatory stimulation with relative external dead space loading does not impact sex differences in exertional dyspnoea
Myosin motor dynamics and cardiac function: Insights from in vivo small-angle X-ray scattering and pressure–volume analysis
4D ultrasound reveals regional left atrial strain remodelling in a murine model of reversible pressure overload
APD restitution controls arrhythmia emergence in cardiac tissue with RyR2 dysfunction
In silico predictions of action potential propagation in doxorubicin cardiotoxicity: A parametric study using preclinical 3D magnetic resonance imaging-based fibrotic left ventricle models
Dietary flavanols preserve upper‐ and lower‐limb endothelial function during sitting in high‐ and low‐fit young healthy males
Anatomical and functional mapping of vagal nociceptive sensory nerve subsets innervating the mouse lower airways by intersectional genetics
Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes
Beat‐to‐beat QT interval variability as a tool to detect the underlying cellular mechanisms of arrhythmias
Mechanistic insights into sex differences in atrial electrophysiology and arrhythmia vulnerability through sex‐specific computational models
Unveiling sex dimorphism in the healthy cardiac anatomy: Fundamental differences between male and female heart shapes
Role of baroreflex feedback loop in predictions of left ventricular growth: A multiscale finite element modelling study
Myosin‐binding protein C slows cardiac myofibril relaxation kinetics
Exercise‐induced arterial hypoxaemia in patients with heart failure with preserved ejection fraction
Danicamtiv increases cardiac mechanical efficiency
Computational modelling of the impact of anatomical changes on ECGs in left ventricular hypertrophy
Blebbistatin reduces calcium buffering in cardiomyocytes: Consequences for cellular electrophysiology
Insights from electromechanical simulations to assess omecamtiv mecarbil efficacy in heart failure
Molecular and pharmacological evaluation of rare, cystic fibrosis‐causing missense mutations of the CFTR channel
The endogenous circadian system impairs nighttime blood pressure responses to active standing in older adults
Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient
Metabolite‐sensitive cross‐bridge models of human atria reveal the impact of diabetes on muscle mechanoenergetics
Mechanisms underlying local Ca2+ signalling differences between right and left atrial myocytes at normal and increased frequencies
The influence of delayed ventricular activation on cardiac repolarization: Insights from electrocardiographic imaging
Computational modelling of the pro‐ and antiarrhythmic effects of atrial high rate‐dependent trafficking of small‐conductance calcium‐activated potassium channels
Virtual left atrial appendage occlusion in paroxysmal atrial fibrillation during sinus rhythm predicts variable reductions in blood stasis
118
Long-term survival after percutaneous coronary intervention or coronary artery bypass grafting in patients with diabetes and multivessel disease
Impact and Outcomes of Failure Mode Following Mitral Valve Repair
Rationale of Functional Tricuspid Annular Dilatation Based on Standardized Intraoperative Measurements
Trends in Aortic Valve Reintervention: Incidence and Outcomes after Failed TAVI Among Medicare Patients
Long-Term Outcomes of Postoperative Atrial Fibrillation After Cardiac Surgery: Results from 19,000 Patients
Left Ventricular Rehabilitation after Ross operation for Critical Aortic Stenosis with Endocardial Fibroelastosis
Extended Arch Replacement Is Associated with Improved Long-Term Outcomes in Acute Type A Aortic Dissection with Ascending Entry Tear
Does the Genotype of Hypertrophic Cardiomyopathy Impact the Outcomes of Septal Myectomy?
Ten-year outcomes of valve-replacing versus valve-sparing aortic root replacement in Marfan syndrome patients: An observational multicenter study
Simulations Predict Improved Valve Performance Without Direct Leaflet Intervention After Neonatal Truncus Arteriosus Repair
Randomized trial of tricuspid flexible band versus rigid ring in patients with moderate tricuspid regurgitation or greater: results of the JPH2019 trial
Outcomes of Adults with Congenital Heart Disease Undergoing Heart and Heart-Liver Transplantation: A Single-Center Experience
A Prospective, Multicenter Trial of Irrigated Radiofrequency Ablation and Cryoablation to Treat Non-Paroxysmal Atrial Fibrillation
Ostial Occlusion of All Epicardial Coronary Arteries: Living off Bypass Grafts
VIRTUAL REALITY IN PLANNING IN COMPLEX HEART SURGERY
Safety and Efficacy of a Dedicated Pulmonary Thromboendarterectomy Fellowship: the UK Experience at a High-Volume Center
Morbidity and Mortality Outcomes of Surgical Versus Transcatheter Aortic Valve Replacement in Dialysis-Dependent Patients
Regurgitant Jet Type Predicts Autograft Outcomes After the Ross Procedure in Congenital Patients
Cardiac Reoperations in Patients with Prior Thoracic Radiation: A Single-Center Analysis of Outcomes and Key Lessons
25-Year Outcomes Following the Regionalization of Three Competing Pediatric Cardiac Surgery Programs
Multi-Center Comparison of Hybrid and Norwood Procedure in Patients with Fontan Circulation
Mechanical versus bioprosthetic heart valves in patients on hemodialysis
Clinical Value of the Flow-Adjusted Pressure Gradient in Patients Undergoing Surgical Aortic Valve Replacement
Outcomes of Staged Repair Following Systemic-to-Pulmonary Artery Shunt in Pulmonary Atresia with Ventricular Septal Defect
Pathology of Explanted Novel ePTFE Pulmonary Valved Conduits Reveals Paucity of Leaflet Tissue Response but Frequent Non-Adherent Thrombus Formation
Risk prediction for surgery on adults with congenital heart disease: Nonprocedural clinical and social factors predominate
Volume–outcome relationship of mortality following surgical explant of transcatheter aortic valve replacements
Changes in ejection fraction after coronary artery bypass grafting for ischemic cardiomyopathy: Impact on survival and determinants of improvement
Posterior wall thickness associates with outcomes after septal myectomy in childhood hypertrophic obstructive cardiomyopathy——original article
Impact of Membranous Septum Length and Valve Calcification on Permanent Pacemaker Implantation After Surgical Aortic Valve Replacement
Integrin αV emerges as a potential therapeutic target with cautionary implications in thoracic aortic aneurysm and dissection
Impact of reoperation on very long-term survival in patients with failed mitral valve repair: A 30-year single-center Canadian experience
Suppression of fibroblastic activity prolongs cardiac transplant survival through targeting their ATG5 expression
Mid-term outcomes after aortic valve repair with the internal geometric annuloplasty ring
The influence of reoperation on aortic arch reconstructive surgery: Evidence from a multicenter, national registry
Sodium-glucose cotransporter 2 inhibitor use and outcomes after surgical aortic valve replacement
Septal leaflet augmentation during Da Silva cone repair: Valvar function and anatomic features compared to nonpatch repair
Optimal strategy for aortic root replacement in patients of advanced age: Valve-sparing root replacement or Bio-Bentall?
Fontan pathway diameter in adults undergoing exercise catheterization: Association with hemodynamics, exercise capacity, and liver scores
Using preoperative cardiac computed tomographic conduction axis prediction to avoid damage in congenital left ventricular outflow tract and aortic valve surgery
Comparison of continuous and interrupted sutures in tracheal resection and anastomosis: A cohort study with propensity score matching
Complications following airway resections: Insights from a large contemporary multi-institutional cohort
Comparison of myocardial mechanics after mitral valve repair with leaflet preservation versus leaflet resection: A subanalysis of the randomized Canadian Mitral Research Alliance CardioLink-2 trial
Quality of life after mitral valve surgery: Results from the Cardiothoracic Surgical Trials Network
Aortic remodeling and pulmonary autograft performance over 2 decades after the Ross procedure in the pediatric and young adult population
Microinvasive, off-pump, transventricular neochordae implantation in recurrent mitral valve regurgitation after open heart surgical repair
Diastolic dysfunction persists 3 months after surgical revascularization in a large animal model of hibernating myocardium
Long-term outcomes of aortic valve repair in children after infancy
Valve characteristics and surgical options for severe rheumatic mitral stenosis with more than mild regurgitation: A dual-center retrospective study
Second cross-clamp in less invasive mitral valve repair for degenerative mitral regurgitation: Predictors and outcomes
Acute type A dissection with iliofemoral or renal malperfusion: Is frozen elephant trunk necessary?
Contemporary outcomes and health care costs associated with single-ventricle heart failure admissions in adults in the United States
A novel rat model for group 2 pulmonary hypertension by total pulmonary vein banding: Multi-omics insights into pathophysiological mechanisms
Mitral valve repair by right minithoracotomy compared with sternotomy: 21-year single-center experience
Impacts of atrial fibrillation and surgical ablation on rheumatic and degenerative mitral surgeries
Development of a patient-specific Fontan failure risk calculator using machine learning—a step toward personalized medicine
Type A aortic dissection during pregnancy and postpartum: Experience in 60 patients over 25 years
Primary biventricular repair in neonates with borderline left ventricle
Outcomes of Fontan patients undergoing combined heart-liver transplantation in pediatric hospitals across the United States
Intraoperative predictors of left atrioventricular valve reoperation after repair of complete atrioventricular septal defect
Outcomes of ischemic mitral regurgitation after coronary revascularization alone in patients with acute coronary syndrome
Replacement of the superior vena cava by the bovine pericardium conduit: Sustained patency without long-term anticoagulation
Comparison of bovine jugular vein conduits and polytetrafluoroethylene valved conduits for right ventricular outflow tract reconstruction
Worse Survival in Transcatheter Aortic Valve Replacement with Untreated Tricuspid Regurgitation: Implications for Surgical Intervention
Single Incision Minimally Invasive Congenital Heart Surgery – Insights into Program Development and Outcome
Tricuspid annular remodeling in tachycardia induced cardiomyopathy with functional tricuspid regurgitation
Ex Vivo Heart Perfusion Offsets Ischemic Penalties with ≥6-Hour Preservation in Adult Donation-After-Brain-Death Heart Transplantation
Computational fluid dynamics-based risk stratification of modified Blalock-Taussig-Thomas shunt thrombogenicity
Long-term outcomes of isolated tricuspid surgery in 3706 patients: Implications for the future
Iatrogenic aortic dissection: Insights from the International Registry of Acute Aortic Dissection
A surgeon's toolkit for mitral valve–induced left ventricular outflow tract obstruction with minimal septal hypertrophy
Early outcomes of chimney commando procedure in redo double valve replacement: A retrospective cohort study
Totally thoracoscopic transmitral versus transaortic septal myectomy for hypertrophic cardiomyopathy: A propensity score−matched comparative study
Mitral valve repair versus bioprosthetic replacement outcomes in patients with rheumatic disease over 60: Propensity score–matching results
Association of increased red blood cell distribution width with adverse cardiorenal outcomes after cardiac surgery
Long-Term Outcomes for Patients Undergoing Hybrid Ablation for Atrial Fibrillation
Cardiopulmonary Effects of Vasopressin Versus Norepinephrine in Cardiac Surgery Patients: a Single Cluster-Randomized Cross-over Trial
Intention-to-treat Outcome Analysis for Valve Sparing Aortic Root Replacement: Is There a Price to Pay for Failure?
Unplanned reinterventions after congenital cardiac surgery and hospital mortality: A report from the Pediatric Cardiac Critical Care Consortium (PC4)
Thirty years of left atrioventricular valve reoperations following atrioventricular septal defect repair: Impact of valvar stenosis
Eliminating the learning curve in robotic mitral valve repair: Results from 1400 patients
Shifting strategies to address systemic outflow tract obstruction in single ventricle anatomy with transposed great arteries
Outcomes of thoracoabdominal aortic aneurysm repair in patients with and without peripheral arterial disease
Reversed septal motion in congenital corrected transposition of the great arteries: A potential mechanism for tricuspid regurgitation
Pulmonary valve repair at the time of the Ross procedure: a safe and durable strategy to address post-implantation aortic regurgitation
Metformin’s Effects Beyond Ischemia: Evaluating Cardioprotection in Non-Ischemic Myocardium in a Large Animal Model of Coronary and Metabolic Disease
Risk of Reoperation Following Rheumatic Mitral Repair: Long-term Longitudinal Analysis
Long-term Clinical Outcomes of 1020 Open Repairs of Descending Thoracic and Thoracoabdominal Aortic Aneurysms
Extra-cardiac conduit restriction is associated with increased liver fibrosis in adolescent Fontan patients
Interpretable Artificial Intelligence to Predict Preoperative Risk Factors for Failure to Rescue after Coronary Artery Bypass Grafting
Prognostic impacts of biological valve size on long-term outcomes of primary surgical aortic valve replacement for aortic stenosis
Pediatric heart transplant in donation after circulatory death using normothermic regional perfusion
Role of primary sternal closure in early outcomes following the Norwood procedure
Impact of Effective Orifice Area on Long-Term Survival in Bioprosthetic versus Mechanical Aortic Valves
Nanosecond Pulsed Field Ablation: Feasibility of Creating the Cox-Maze Lesion Set on the Beating Heart
Platelet Responsiveness to Aspirin in Pediatric Patients Undergoing Cardiac Surgery – A Prospective Cohort Study
Novel Anastomotic Device for the Sandwich Technique in Type A Aortic Dissections – A Human Cadaver Study
Autograft Reinforcement in the Ross Procedure: A Systematic Review and Patient-level Meta-Analysis
Oral anticoagulation in patients with atrial fibrillation and heart valve prosthesis: a substudy from the LAAOS III Trial
Impact of Preoperative CT Planning on Surgical Outcomes in Patients with Obstructive Hypertrophic Cardiomyopathy: A Prospective Cohort Study
Effect of Celsior Cold Storage on Warm Ischemia-Induced Myocardial Plasma Membrane Damage and Pyroptosis in Human Hearts from Circulatory Death Donors
Device closure versus surgical repair for doubly committed subarterial ventricular septal defect
Survival trends of adults with congenital heart disease after heart surgery in Sweden
Targeted immunotherapy with sphingosine-1-phosphate improves myocardial contractility and mitochondrial function in a novel murine ex vivo perfusion and transplantation model
Transcatheter Edge-to-Edge Repair versus Mitral Valve Surgery in Octogenarians: Comparative Analysis of Safety, Durability, and Survival
Ventricular Arrhythmias in Patients Undergoing Degenerative Mitral Repair: Prevalence and Impact on Survival
Challenging the Transcatheter-First Paradigm: Redo Surgical Aortic Valve Replacement After Prior Transcatheter or Surgical Aortic Valve Replacement
Five-Year Experience of Heart Transplantation Following Donation After Circulatory Death
Symptomatic Myocardial Bridge: Long-term Outcomes and Strategies
Personalized External Aortic Root Support, the Dutch Experience
Predictors and Prognosis of Mild Regurgitation After Rheumatic Mitral Valve Repair: A Dual-Center Cohort Analysis Based on Cardiac Computer Tomography
A cohort evaluation of surgical pathways reported to a national audit of children undergoing treatment for congenital heart disease in England and Wales
Growth of the Fontan Pathway and its Association with Long-Term Outcomes
Outcomes Following Repair of Truncus Arteriosus with Interrupted Aortic Arch
Risk Stratification of CABG Patients Using an Artificial Intelligence ECG-Derived Age
Early extraction versus conservative management in patients with non-infected cardiac implantable electronic devices undergoing cardiac surgery for left-sided infective endocarditis: Insights from the multicentric CAMPAIGN Registry
Coronary revascularization in France: six-year trends and outcomes in coronary artery bypass grafting and percutaneous coronary intervention
Neo-aortic valve regurgitation and root dilation after arterial switch operation in patients with native left ventricular outflow tract obstruction
2
Complication outcomes in retroauricular interpolated flaps after Mohs surgery: A single-center retrospective study
Avapritinib improves cutaneous involvement in patients with indolent systemic mastocytosis: Results from the randomized, phase 2, interventional PIONEER study
4
Inhalable Polymeric PROTAC Nanococktail for Targeted Protein Degradation in Idiopathic Pulmonary Fibrosis
Nitrite as a Synthon for Nitroxyl (HNO): Mechanistic Insights and Chemical Evidences of Transient Intermediates
Biorthogonal PEGylation of Hierarchical Porous Metal–Organic Frameworks as Robust, Functional Nanocarriers for Hemoglobin-Based Oxygen Delivery
Nitrite Causes Nitrosative Stress to Iron Sulfur Clusters
138
Contemporary Outcomes of the Ross Procedure in Adults
Long-Term Outcome of Myectomy Associated With Secondary Mitral Valve Chordal Cutting in Obstructive Hypertrophic Cardiomyopathy
Population Prevalence of Valvular Heart Disease in the United States
10-Year Outcomes of SAPIEN 3 Transcatheter Aortic Valve Replacement or Surgery in Intermediate-Risk Patients
Effects of Finerenone on Sudden Death Across the Cardio-Kidney-Metabolic Landscape A FINE-HEART Analysis
Estimating the Effects of MTEER in U.S. Practice
Kidney and Survival Benefits of Semaglutide in Diabetes With Chronic Kidney Disease
Implications of Modest Reductions in ABI Measurements for Risk of Major Adverse Limb Events Among 223,350 Veterans
Risk-Based Nurse-Managed Personalized Heart Failure Interventions
Anti-inflammatory effects of oral NLRP3 inhibition with ruvonoflast among individuals at elevated cardiovascular risk
Monogenic ALB Variants as Determinants of Severe Hypercholesterolemia A Population-Based Cohort Study
Effectiveness and Safety of Early Rhythm Control in Patients With Atrial Fibrillation and Chronic Kidney Disease
ECG Signatures and Long-Term Ischemic Stroke Risk A Deep Learning Analysis of 200,000 Patients
Long-Term Outcomes of a Drug-Eluting Resorbable Scaffold vs Angioplasty in Infrapopliteal Chronic Limb-Threatening Ischemia 3-Year Results From the LIFE-BTK Trial
Multiarterial Grafting and Survival After Coronary Artery Bypass Grafting
Aligning Coronary Stent Trial Enrollment With the U.S. Intended-Use Population
Sudden Cardiac Death and its Relation to Previously Diagnosed or Occult Cardiac Disease at Autopsy
Sudden Cardiac Death Due to Myocardial Infarction With Obstructive and Nonobstructive Coronary Arteries
Randomized Trial of Left Bundle Branch Pacing vs Right Ventricular Pacing in Vulnerable Cardiac Function
Body Mass Index, Clinical Outcomes, and Mortality in Heart Failure: A Mendelian Randomization Study
Focal and Diffuse Coronary Artery Disease Patterns and Placebo-Controlled Angina Relief With Percutaneous Coronary Intervention
Midlife Cardiorespiratory Fitness and Healthy Aging
Comparative Cardiovascular Effectiveness of Glucagon-Like Peptide 1 Receptor Agonists and Sodium-Glucose Cotransporter 2 Inhibitors in Diabetes Mellitus
Sirolimus-Eluting Balloon vs Repeat Drug-Eluting Stent or Balloon Angioplasty for Coronary In-Stent Restenosis
Risk-Guided Atrial Fibrillation Screening With Artificial Intelligence–Enabled Electrocardiogram Models
Blood Pressure Trajectories and Cardiovascular Outcomes in Older Patients
Opportunistic Cardiovascular Risk Assessment Using Routine Head CT in the Emergency Department
Cardiovascular Disease Risk in Adults With Hematological Malignancies
Quality of Life After Percutaneous Coronary Intervention or Medical Therapy for Chronic Total Coronary Occlusions: EUROCTO and DECISION-CTO Meta-Analysis
Achieving Intensive Blood Pressure Control in High-Risk Patients: Implementation Insights From the ESPRIT Trial
Long-Term Cardiovascular and Noncardiovascular Mortality After Acute Coronary Syndrome
Oral PCSK9 Inhibitor Enlicitide Versus Oral Nonstatin Therapies: A Phase 3 Randomized Clinical Trial
A Randomized, Placebo-Controlled Trial of Chronic Total Occlusion Percutaneous Coronary Intervention in Stable Angina - ORBITA-CTO
Automated Alerts to Improve Timely Evaluation and Treatment of Valvular Heart Disease: The ALERT Trial
Atrial Functional Mitral Regurgitation
Combining Genomics With Lipid and Inflammatory Biomarkers to Predict Coronary Artery Disease Risk
Cardiomyopathy Gene Variants and Polygenic Risk Scores in Atrial Fibrillation
Use of Coronary Artery Calcium Scoring in Individuals With Elevated Lipoprotein(a)
Comparative Prognosis of Chagas and Other Cardiomyopathies
Interchangeability of the KCCQ-12 and KCCQ-23 across gt;18,000 Participants Enrolled in 4 Large-Scale Trials of Heart Failure
Genotype-Guided Risk Stratification of Mitral Valve Surgery in Marfan Syndrome
Single-Ventricle Disease
Preferences for Antihypertensive Prescribing in Older Adults
Use of the Ross Procedure in North America
Mitral Annular Calcification-Related Mitral Stenosis: 5-Year Outcomes and Prognostic Determinants in the JAMAC Study
Varenicline and Ventricular Ectopy After Myocardial Infarction: A Randomized Phase 2 Study
Real-Time Heart Team for Revascularization in Complex Coronary Artery Disease
Beta-Blocker (Bisoprolol) vs Calcium-Channel Blocker (Verapamil) in Nonobstructive Hypertrophic Cardiomyopathy
Sotatercept in Pulmonary Arterial Hypertension
Cardiac Screening for Conditions Associated With Sudden Cardiac Death: Yield, Interventions, and SCA/SCD Incidence in 104,369 Young Individuals
Mitral Valve Repair for Degenerative MR With Moderate or Less Tricuspid Regurgitation: 2-Year Outcomes From a Multicenter Echocardiographic Core Laboratory–Adjudicated Cohort
Comparison of Sirolimus- vs Paclitaxel-Coated Balloon Angioplasty for Femoropopliteal Artery Disease: The SIRONA Randomized Noninferiority Trial
Polygenic Risk Based Detection and Treatment of Subclinical Coronary Atherosclerosis in the PROACT Clinical Trials
Effect of Baduanjin on Blood Pressure Among Individuals With High-Normal Blood Pressure: A Multicenter, Open-Label, Blinded-Outcome Randomized Controlled Trial
Atrial Mechanical Contraction Predicts Cerebrovascular Risk in Patients With Transthyretin Amyloid Cardiomyopathy and Sinus Rhythm
Sirolimus-Eluting Iron Bioresorbable Scaffolds vs Everolimus-Eluting Stents for Percutaneous Coronary Intervention: A Randomized Trial (IRONMAN II)
Pulsed Field Ablation vs Standard Radiofrequency Ablation for Typical Atrial Flutter: ADVANTAGE AF Trial Substudy
Public Reporting and Case Selection in Congenital Heart Surgery Signals From a Multicenter Observational Study
Association Between Age and PCI Effectiveness in Stable CAD Secondary Analysis of ORBITA-2
Enhanced Detection and Prompt Diagnosis of Atrial Fibrillation Using Apple Watch A Randomized Controlled Trial
Hospitalizations and Mortality Among Medicare Beneficiaries at Cardiovascular Risk Disruptions and Recovery From the COVID-19 Pandemic
Blood Pressure Levels and Outcomes in Type 2 Diabetes Dose-Response Meta-Analysis of 5.87 Million Cohort Participants
Natriuretic Peptide Receptor-1 Agonist for Resistant Hypertension A Randomized Phase 2 Trial
Pulsed-Field Ablation to Enhance the Durability of Pulmonary Vein Isolation and Treat Paroxysmal Atrial Fibrillation
Heart Failure Quality of Care Among Asian Patients in the United States
Echocardiographic Diastolic Function Grading in HFpEF Testing the Updated 2025 ASE Criteria
Loss of Y Chromosome and Major Cardiovascular Events in a Prospective Study of Older Men
Delayed Diagnosis of Transthyretin Amyloid Cardiomyopathy in the Veterans Health Administration
Obesity-Associated Cardiovascular Risk and Benefit From PCSK9 Inhibition A Prespecified Analysis From FOURIER
Prevalence, Awareness, and Treatment of Hypertension in 37 African Countries Trends From 2003 to 2022
Association of Lp(a) With Cardiovascular Disease and All-Cause Mortality in U.S. Hispanics and Latinos
Pulsed Field Ablation Using a Novel Biphasic Catheter vs Thermal Ablation for Paroxysmal Atrial Fibrillation InsightPFA Trial
Early vs Late Staged PCI After Subintimal Tracking and Re-Entry for Chronic Total Occlusions A Randomized Trial
Trends in Prevalence, Treatment, and Control of Cardiometabolic Risk Factors Among Adults With Hypertension in the United States, 1999-2023
Trends in the Prevalence, Associated Risk Factors, and Health Burden of Heart Failure in the United States, 1988 to 2023
Behavioral Economics and Medication Adherence for Hypertension: A Randomized Clinical Trial
Aficamten in Obstructive Hypertrophic Cardiomyopathy: A Multi-Domain, Patient-Level Analysis of the MAPLE-HCM Trial
Potent P2Y12 Inhibitor Monotherapy versus DAPT after PCI in Patients With and Without STEMI: NEO-MINDSET Substudy
One-year outcomes of novel balloon-expandable versus contemporary transcatheter heart valves in severe aortic stenosis: the LANDMARK trial
Proactive Management and Treatment of Aortic Stenosis: An International Expert Perspective
Sex-Specific Microaxial Flow Pump Use and Outcomes in Infarct-Related Cardiogenic Shock in the DanGer Shock Trial
Incremental Value of Cardiac Myosin-Binding Protein C for the Early Diagnosis of Acute Myocardial Infarction
Follow-up Lipid Testing and Statin Initiation among Young Adults in a US Healthcare System
Association of Lipoprotein(a) and Interleukin-6 With Cardiovascular Risk MESA and UK Biobank
Multicenter Study on the Safety of Pulsed Field Ablation in Over 40,000 Patients: MANIFEST-US
Using Artificial Intelligence to Adjudicate Major Adverse Cardiovascular Events in Clinical Trials
Using Transmitral Pressure Gradients and Residual Mitral Regurgitation to Optimize Outcome After Transcatheter Edge-to-Edge Repair
Safety of Using Risk Stratification Along With High-Sensitivity Cardiac Troponin in the Emergency Department A Secondary Analysis
Atrial Fibrillation Screening According to Genetic Risk A Secondary Analysis of the Randomized LOOP Study
Tricuspid Regurgitation Across the Spectrum of Heart Failure With Preserved Ejection Fraction
Intracoronary Low-Dose Recombinant Tissue Plasminogen Activator in Primary PCI for ST-Segment Elevation Myocardial Infarction and Large Thrombus Burden: A Randomized Trial
Drug-coated balloon angioplasty versus upfront stenting for de novo CAD: 3-year follow-up of REC-CAGEFREE I trial
Transcatheter Mitral Valve Replacement for Severe Mitral Annular Calcification: Primary Outcomes from the SUMMIT-MAC Study
Economic outcomes and quality of life after CABG or PCI for multivessel disease: The FAME 3 Trial
Long-Term Effect of ICDs in Nonischemic Heart Failure With Reduced Ejection Fraction Extended Follow-Up Analysis of DANISH
Using PREVENT Equations to Compare Intensive vs Standard Systolic Blood Pressure Control for Primary Prevention in SPRINT
Modest Effects of Intensive Blood Pressure–Lowering on Quality of Life in Patients at High Cardiovascular Risk The ESPRIT Trial
Intensive Blood Pressure Control in Older Patients With Hypertension 6-Year Results of the STEP Trial
Effects of Intensive Blood Pressure Control in Patients With Frailty A Post Hoc Analysis From ESPRIT
LDL-C related cardiovascular burden in China 2010-2030: Spatiotemporal patterns and scenario-based projections
Effect of Dapagliflozin on Quality of Life of Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Implantation
Very High Prevalence of Nonoptimally Controlled Traditional Risk Factors at the Onset of Cardiovascular Disease
Mechanical Vacuum Aspiration and Debulking of Large Vegetations During Cardiac Implantable Electronic Device Extraction
Danicamtiv, a selective agonist of cardiac myosin, for dilated cardiomyopathy: A Phase 2 open-label trial
Association Between Anticoagulant Therapy and Survival in Pulmonary Arterial Hypertension A Registry Report and Updated Meta-Analysis
Remnant Cholesterol as an Independent Cardiovascular Risk Factor in Young Adults : An Age-Stratified Cohort Study
Intensive vs Conventional Intraoperative Blood Pressure Management on Cardiovascular Events After Major Abdominal Surgery The BP-CARES Randomized Trial
Safety and Effectiveness of Statins for Primary Prevention in Adults With Type 1 Diabetes An Emulation
Trajectories of Angina After Initial Invasive vs Conservative Strategy for Chronic Coronary Disease
Left Ventricular Health and TAVR Timing in Asymptomatic Severe Aortic Stenosis: Analysis from the EARLY TAVR Trial
Artificial Intelligence Automation of Echocardiographic Measurements
Incidence of Heart Failure in Asian American, Native Hawaiian, and Other Pacific Islander Populations
Impact of Obicetrapib on Major Adverse Cardiovascular Events in High-Risk Patients A Pooled Analysis
Pathogenic Cardiomyopathy-Associated Gene Variants and Prognosis in Atrial Fibrillation Results in 18,000 Clinical Trial Participants
Sex Differences in Effectiveness of Semaglutide in Patients with Peripheral Artery Disease: The STRIDE Trial
Computed Tomography Angiography or Standard Care After Left Main PCI?
Twice-A-Day CLOpidogrel vs Ticagrelor to Reduce Short-Term MACE after Primary PCI: The TADCLOT Trial
Personalized or Standard Duration of Dual Antiplatelet Therapy after Percutaneous Coronary Intervention: PARTHENOPE Randomized Trial
Colchicine and Longitudinal Dynamics of Clonal Hematopoiesis: An Exploratory Substudy of the LoDoCo2 Trial
Effect of Intensive Blood Pressure Control on Stroke A Prespecified Secondary Analysis of the ESPRIT Trial
A Polygenic Risk Score to Predict Incident Heart Failure Across the Spectrum of Cardiovascular Risk
Natriuretic Peptides, Body Mass Index, and Clinical Outcomes in Heart Failure with Mildly Reduced or Preserved Ejection Fraction
Effect of Vericiguat on Worsening Heart Failure in Compensated Outpatients with HFrEF: Insights from VICTOR
Echocardiographic Changes With Mavacamten in Nonobstructive Hypertrophic Cardiomyopathy Exploratory Insights From the ODYSSEY-HCM Trial
Effect of Aficamten Compared with Metoprolol on Echocardiographic Measures in Symptomatic Obstructive Hypertrophic Cardiomyopathy: MAPLE-HCM
Effects of Mavacamten on Cardiac Biomarkers in Nonobstructive Hypertrophic Cardiomyopathy Insights From the ODYSSEY-HCM Trial
Anthropometric Measures, Cardiovascular Outcomes, and Treatment Effects of Finerenone in Cardiovascular-Kidney-Metabolic Disease: Pooled Participant-Level Analysis of Three Global Trials
Causes of Myocardial Infarction in Younger Patients Troponin-Elevation in Persons ≤65 Years Old in Olmsted County
Prevalence and Predictors of Neurocognitive Dysfunction in Adults With Congenital Heart Disease Results From MINDS-ACHD
Clinical Outcomes of Conduction System Pacing vs Right Ventricular Septal Pacing in Atrioventricular Block The CSPACE Randomized Controlled Trial
Paclitaxel-Coated Balloon for the Treatment of Multilayer In-Stent Restenosis AGENT IDE Subgroup Analysis
Guideline-Directed Medical Therapy and Outcomes Among Patients With Heart Failure With Improved Ejection Fraction
Sodium-Glucose Cotransporter 2 Inhibitor With and Without an Aldosterone Antagonist for Heart Failure With Preserved Ejection Fraction The SOGALDI-PEF Trial
Global Impact of Fixed-Dose Combination Therapies on Cardiovascular Mortality and Events, 2023-2050 A Modeling Study
AHA PREVENT Equations and Cardiovascular Disease Risk in Diverse Health Care Populations
Plaque Vulnerability and Cardiovascular Risk Factor Burden in Acute Coronary Syndrome An Optical Coherence Tomography Analysis
Catheter Ablation vs Lifestyle Modification With Antiarrhythmic Drugs to Treat Atrial Fibrillation PRAGUE-25 Trial
3-Year Clinical Outcomes Comparing the Amulet vs Watchman FLX for Left Atrial Appendage Closure in Patients With Atrial Fibrillation Results From the SWISS-APERO Randomized Clinical Trial
9
Angiotensin Receptor Blockers Versus Calcium Channel Blockers for First‐Line Antihypertensive Therapy and Survival in Adults Aged 75 Years or Older
Outcomes After Percutaneous Coronary Intervention for Chronic Coronary Disease in Adults ≥ 75 versus lt; 75 Years
Outpatient Cardiac Rehabilitation and Long‐Term Clinical Outcomes After Transcatheter Aortic Valve Replacement
Post‐Stroke Atrial Fibrillation Detection With Insertable Cardiac Monitors in Patients With Dementia and Frailty
Patterns of Oral Anticoagulant Use in Atrial Fibrillation Following Transition to Long‐Term Care
Hypertension Prevalence Among Centenarians: Data From the Chinese Longitudinal Healthy Longevity Survey
Worldwide Burden of Pulmonary Arterial Hypertension in Adults Aged 65 Years and Older From 1990 to 2021
Appropriateness of Antiplatelets and Anticoagulants Among Older Adults Experiencing Falls
Emergency Department Visits for Bleeding by Adults Aged ≥ 80 Years Receiving Direct‐Acting Oral Anticoagulants
5
Acute eGFR Changes and Their Mediation of Albuminuria Reduction with Empagliflozin and Finerenone.
Association of Sphingolipids with All-Cause and Cardiovascular Death in Patients with Kidney Failure Treated with Maintenance Hemodialysis
Baseline Kidney Function, Albuminuria, and Urine Albumin-Creatinine Ratio Reduction with Finerenone, Empagliflozin, or Both: Post Hoc Analyses of CONFIDENCE Trial.
Computational Characterization of Lymphocyte Topology on Whole Slide Images of Glomerular Diseases.
Loop Diuretic Dose Intensification versus Adjuvant Thiazide for Diuretic Resistance in Acute Heart Failure: Mechanistic Randomized Controlled Trial.
9
Cardiovascular disease risk after radiotherapy and anthracycline-based chemotherapy for diffuse large B-cell lymphoma
Deployment to Karshi-Khanabad Air Base, Uzbekistan between 2001 and 2005 and subsequent risk of specific cancers among US service members
Cardiovascular disease risk among long-term testicular cancer survivors following contemporary cisplatin-based chemotherapy
Influence of treatment, genetic predisposition, and lifestyle on cardiovascular risk factors among cancer survivors
Lymphocyte count and risk of chronic lymphocytic leukaemia
Cardiovascular risk in long-term survivors of breast, prostate, colon, and rectal cancer
Risk of lymphoma among people with HIV in the United States, 2001-2019
Polygenic risk of coronary artery disease for long-term survivors of breast cancer
Meeting trial eligibility in follicular lymphoma patients is associated with overall survival but not progression-free survival
2
The role of C-C motif chemokine ligand 2 in the preservation of myogenic tone in the kidney microvasculature of Dahl Salt-Sensitive rats
Telomere recapping via gene therapy as a beneficial strategy for cardio-renal syndrome type 4
1
Nitric oxide drives proteomic diversity through alternative splicing
1
Aberrant calcium signaling and neuronal activity in the L271H CACNA1D (Cav1.3) iPSC model of neurodevelopmental disease
2
Inhalable Macrophage Membrane-Camouflaged Hyperbranched Polymeric Nanoparticles for Acute Lung Injury Treatment
Characterizing Integrin Tensions during Platelet Adhesion and Stiffness Sensing
10
An ECG biomarker for sudden cardiac death discovered with deep learning
Passive heart-rate monitoring during smartphone use in everyday life
Engineered immunosuppressive dendritic cells protect against cardiac remodelling
Clinical application of base editing for treating β-thalassaemia
Reduced cyclin D3 expression in erythroid cells protects against malaria
Comprehensive echocardiogram evaluation with view primed vision language AI
A neuronal architecture underlying autonomic dysreflexia
Epithelial cell membrane perforation induces allergic airway inflammation
Imidazole propionate is a driver and therapeutic target in atherosclerosis
Detecting structural heart disease from electrocardiograms using AI
161
Emergence of fibrotic pericytes and their transcriptional regulation in pulmonary fibrosis
Systemic atopy and upper-airway disease define susceptibility to incident asthma after COVID-19 in Korea
MYDGF promotes pathological and physiological retinal angiogenesis via the Gαi1/3-Gab1-Akt-mTOR signaling
Sex representation in trials relative to indication-specific disease burden in FDA-approved drugs (2015–2023)
Pulmonary inflammation in severe pneumonia is characterised by compartmentalised and mechanistically distinct sub-phenotypes
Liposomal mitoxantrone plus tislelizumab in patients with relapsed or refractory extranodal natural killer/T-cell lymphoma: a phase 1b/2 trial
Inhibition of the QPCT–PDIA4 axis rescues ΔF508 and N1303K CFTR in cystic fibrosis
Single-cell whole-genome sequencing reveals convergent evolution in Burkitt lymphoma
Optimal blood pressure target in patients with uncomplicated hypertension: a target trial emulation study
Dynamics of the β-cardiac myosin auto-inhibited state explain cardiomyopathy pathogenesis
Non-contact on-device detection of obstructive sleep apnea from infrared video
Compliance modulation of a soft robotic atrioventricular model of heart failure with preserved ejection fraction
TAK1 drives inflammatory fibroblast acquisition and shapes myocardial infarction responses in male mice
Measuring multi-site pulse transit time with an AI-enabled mmWave radar
Metabolic and inflammatory biomarker trajectories after a cancer diagnosis and the risk of cardiovascular diseases
Mitochondria-derived vesicles with bioenergetic units from brown adipose tissue attenuate cardiac remodeling post-myocardial infarction
Impact of a whole food, plant-based diet on LDL-cholesterol and cardiovascular risk factors in adults with heterozygous familial hypercholesterolemia: a randomized, two-period, two-treatment, crossover, fully controlled feeding trial
Endothelial Drp1 integrates VEGF-induced redox signaling with glycolysis through cysteine oxidation to drive angiogenesis
Joint clinical and molecular subtyping of COPD with variational autoencoders
Gene-gene interactions between a LMNA variant and common polymorphisms drive early-onset atrial fibrillation
Kynurenic acid mediates epicardial fat-induced lymphatic metabolic dysfunction in atrial fibrillation
Maternal age and pregnancy-related cardiovascular complications
A high dimensionality approach reveals immunopathogenic responses driving severe pediatric acute respiratory distress syndrome
LTBP4 deficiency inhibits NLRP3 inflammasome activation in cardiomyocytes and attenuates heart failure in male mice
Cuffless hemodynamic monitoring with physics-informed machine learning models
Chromatin rewiring of β-globin and MYC enhancers by TGF-β1 drives defective erythropoiesis
A deep learning ECG model for identification and localization of occlusion myocardial infarction
Endothelial-erythrocyte glycocalyx exchange enables liquid biopsies of endothelial function
Persistence of alveolar fibroblast-derived ADAMTS4+ cells in a preclinical model of delayed pulmonary fibrosis resolution
A self-supervised electrocardiogram foundation model for empowering cardiovascular disease prediction and genetic factor discovery
Dietary intake and BCAA metabolism regulate pulmonary fibrosis through KDM4A-mediated epigenetic remodeling in male mice
MicroRNA-30c analog C2 decreases plasma cholesterol and atherosclerosis without causing liver injury in preclinical studies
Glycaemic variability underlies myocyte dysfunction and myocardial injury risk in diabetes
International trade and air-quality-related mortality
Hdac11 promotes idiopathic pulmonary fibrosis through macrophage M2-type polarization and myofibroblast accumulation by inhibiting Parkin-dependent mitophagy
Precision cardiovascular risk prediction in type 1 diabetes: An IMI2 SOPHIA analysis
SLC1A5 prevents aortic aneurysm and dissection by glutaminolytic-epigenetic orchestration of vascular smooth muscle cell homeostasis
Cardiac reprogramming via transient overexpression of P-glycoprotein alleviates doxorubicin-induced cardiotoxicity in mice and pigs
A synthetic angiotensin II/ACE2-based hormone shunt controlling experimental hypertension
PDK4 drives abdominal aortic aneurysm by promoting smooth muscle cell metabolic reprogramming and NLRP3-mediated pyroptosis
Osteoarthritis and analgesic consumption in haemochromatosis HFE C282Y homozygotes with normal or low iron parameters
Structural insights into single-pass transmembrane receptor GC-A activation by distinct antihypertensive antibodies
Macrophage Gsα promotes NLRP3 stability and its intervention attenuates abdominal aortic aneurysm in male mice
Targeting REV-ERBα/BNIP3 axis attenuates pulmonary arterial hypertension by repressing mitophagy in mice
NK cells promote cardiac cell death and regulate myelopoiesis in myocardial infarction
Mitochondrial vulnerability underlies myocarditis from COVID-19 mRNA vaccine
CXCR3 is associated with T-cell-induced heart damage in acute rheumatic fever
Cardiomyocyte-derived GPX4 stabilizes BNIP3 to facilitate mitophagy and mitigate myocardial ischemia/reperfusion injury
Zanubrutinib-rituximab followed by shortened chemoimmunotherapy as frontline treatment for mantle cell lymphoma (CHESS): a phase II trial
Cardiomyocyte Cyclin-dependent kinase 9 directly binds to and phosphorylates NF-κB p65 subunit to drive cardiac inflammation and remodeling
Single-cell multiomics uncovers an endothelial mechanosensitive PIEZO1-IL-33 axis driving pulmonary fibrosis
Endothelial C-type natriuretic peptide/guanylyl cyclase-B signaling prevents pulmonary arterial hypertension
Vascular smooth muscle cell state trajectories mediate molecular mechanisms of coronary disease risk
Pyruvate metabolism enzyme Dlat induces mitochondria protein hyperacetylation to limit fatty acid oxidation in the HFpEF heart
The REDD1–NF-κB–miRNAs–eNOS/SIRT1 axis mediates obesity-induced endothelial cell senescence and hypertension
Optical control of the cardiac rhythm with photoswitchable Na1.5 channel blockers
Single-cell genomics highlight MYC-associated metabolic activation and altered cell interactions in T-prolymphocytic leukemia progression
NPM3 functions as a lactyltransferase to promote necroptosis in male diabetic cardiomyopathy mice models via FASN transcription modulation
Restoration of RBM22 overcomes the transcriptional and epigenetic barriers of cardiomyocyte proliferation for heart regeneration
Amphotericin B promotes respiratory viral entry by enhancing late endosomal maturation and fusion via glucocerebrosidase-mediated ceramide remodeling
A gut microbiome-kidney-heart axis predictive of future cardiovascular diseases
Clusters of vascular aging manifestations predict incident cardiovascular events in the community
Conditional BCL-2 Expression in Fibroblasts Promotes Persistent Pulmonary Fibrosis which is Reversible by Therapeutic BCL-2 Inhibition
Activation of IRF3 in cardiomyocytes impairs mitochondrial oxidative function through PGC-1α inhibition and drives heart failure
TWIST1 drives endothelial-to-mesenchymal-transition to stabilize atherosclerotic plaques
Depression of tryptophan may contribute to adverse effects of naproxen
Human iPSC-based Modeling of Pulmonary Fibrosis Reveals p300/CBP Inhibition Suppresses Alveolar Transitional Cell State
Expert-level probabilistic breathing event detector informs phenotyping of sleep apnea
The landscape of hereditary haemochromatosis risk and diagnosis across the British Isles and Ireland
Tenascin C myofibroblasts exacerbate vascular neointimal hyperplasia by propagation of nerve-macrophage interactions in mice
Endothelial stem cells of the retinal vasculature reside in the optic nerve
A nanosystem targeting tissue inhibitor of metalloproteinase-1 for continuous spatiotemporal idiopathic pulmonary fibrosis therapy
CD39 polymorphism enables lung thrombosis in sickle cell disease
Airway immune profiles and therapeutic implications of IGF1 in eosinophilic granulomatosis with polyangiitis
Non-remnant triglyceride-rich lipoproteins due to lipoprotein lipase deficiency increase atherosclerosis in mice
Endoglin as a BMP9 co-receptor in vascular endothelial cells: prodomain displacement and TGFBRII recruitment
Gut microbiota-derived metabolite isovalerylcarnitine modulates salt sensitivity of blood pressure and incident hypertension: a multicenter dietary salt intervention trial
Evidence for Interleukin-17C governing interleukin-17A pathogenicity and promoting asthma endotype switching in bronchiectasis
Calcium channel blockers increase the risk of aortic aneurysm and dissection
IDH2 lactylation promotes angiogenesis in murine diabetic myocardial infarction via blocking Cav1-eNOS interaction
Single cell spatial transcriptomics integration deciphers the morphological heterogeneity of atherosclerotic carotid arteries
GSDME-dependent pyroptosis drives abdominal aortic aneurysm via promoting vascular senescence
Administrative-driven hierarchical management of atrial fibrillation on cardiovascular events: a prospective matched cohort study
Molecular insights into ago-allosteric modulation at cysteinyl leukotriene receptor 2
MAT2A promotes atherosclerotic plaque vulnerability by mediating epigenetic reprogramming of macrophages
Integrating a host biomarker with a large language model for diagnosis of lower respiratory tract infection
Nano-functionalized probiotic treats atherosclerosis via inhibiting intestinal microbiota-TMA-TMAO axis
Liver-specific paraoxonase-1 alleviates regulatory T cell-driven immunosuppression via metabolic reprogramming in hepatocellular carcinoma
Hic-5 drives epithelial mechanotransduction promoting a feed-forward cycle of bronchoconstriction
Echo-Vision-FM: a pre-training and fine-tuning framework for echocardiogram video vision foundation model
Platelet-bioengineered hiPSC-sEVs achieve targeted repair of fibrotic sinoatrial node in preclinical SND models
A conformal piezoelectric microsystem for demographic-adaptive and calibration-free cuffless blood pressure monitoring
Modifiable influencing factors and their joint effects on early- and late-onset coronary heart disease
Comprehensive profiling of smoke-induced T cells in mice implicates clonal γδT17 cells as a hallmark of COPD
Extracellular activation of HCN4 by a subtype-specific nanobody
A noninvasive machine learning model using a complete blood count for screening of primary vitreoretinal lymphoma
Risk factors for mortality in patients with kidney failure on hemodialysis identified by proteomic analysis of CRIC and PACE studies
Extracellular matrix anchored neutrophils drive pulmonary fibrosis in mice
NLRP3-induced systemic inflammation controls the development of JAK2V617F mutant myeloproliferative neoplasms
Identification of epigenetic regulators of fibrotic transformation in cardiac fibroblasts through bulk and single-cell CRISPR screens
Pharmacogenomics and chronotherapy of drug-induced cardioprotection in acute myocardial infarction
Regional and cell specific bioactivity of injectable extracellular matrix biomaterials in myocardial infarction
Deciphering age- and sex-specific patterns of coronary artery atherosclerosis from a large Chinese cohort
A heterogeneous-structure facial mask for thermal and humidity regulation in cold environments
CFTR modulator therapy drives microbiome restructuring through improved host physiology in cystic fibrosis: the IMMProveCF phase IV trial
Crystal structures of Ryanodine Receptor reveal dantrolene and azumolene interactions guiding inhibitor development
Regulation of lipoprotein processing by GPNMB in foamy macrophages: potential therapeutic targets for atherosclerosis
Functional genomics and tumor microenvironment analysis reveal prognostic biological subtypes in Mantle cell lymphoma
Genome-wide analysis of heart failure yields insights into disease heterogeneity and enables prognostic prediction in the Japanese population
A cross-study transcriptional patient map of heart failure defines conserved multicellular coordination in cardiac remodeling
Multi-cohort high-dimensional proteomics reveals early risk markers for lymphoid cancer subtypes
Ras-related protein 2 limits vascular smooth muscle cell phenotypic switching and abdominal aortic aneurysm development
Predicting hypotension, syncope, and fracture risk in patients indicated for antihypertensive treatment: the STRATIFY models
Eosinophil-derived interleukin-24 compromises epithelial integrity and aggravates airway remodeling in mouse models of allergic asthma
CCL28 contributes to angiogenesis and cardiac repair through CCR10 endothelial cells after myocardial infarction in male mice
A wearable-based aging clock associates with disease and behavior
Chronic kidney disease is associated with increased risk of sudden cardiac death
The CCL20–integrin α5β1 interaction enhances TGF-β/Smad signaling to promote fibroblast activation in pulmonary fibrosis
Reprogramming mitochondrial metabolism and epigenetics of macrophages via miR-10a liposomes for atherosclerosis therapy
Reference values for cardiac dimensions and function in a rural population living in a loiasis-endemic area of the Republic of the Congo: An echocardiographic study
mTOR dysregulation induces IL-6 and paracrine AT2 cell senescence impeding lung repair in lymphangioleiomyomatosis
Adipocyte FMO3-derived TMAO induces WAT dysfunction and metabolic disorders by promoting inflammasome activation in ageing
Hypertrophic cardiomyopathy mutations Y115H and E497D disrupt the folded-back state of human β-cardiac myosin allosterically
Equitable cleanup of Superfund sites leaving no U.S. community behind
An anti-TSLP monoclonal antibody for uncontrolled CRSwNP: the DUBHE randomized clinical trial
Hypoxic conditioning in Parkinson’s disease: randomized controlled multiple N-of-1 trials
Distinct cell state ecosystems for nodular lymphocyte-predominant Hodgkin lymphoma
Macrophage ferroptosis potentiates GCN2 deficiency induced pulmonary venous arterialization
Integrated single-cell atlas of human atherosclerotic plaques
Mepolizumab alters gene regulatory networks of nasal airway type-2 and epithelial inflammation in urban children with asthma
Lymph nodes molecular subtypes unravel lymph nodes heterogeneity and clinical implications in colorectal cancer
Transparent artificial intelligence-enabled interpretable and interactive sleep apnea assessment across flexible monitoring scenarios
Frontline acalabrutinib, lenalidomide and rituximab for advanced stage follicular lymphoma with high tumor burden: phase II trial
Aging affects reprogramming of pulmonary capillary endothelial cells after lung injury in male mice
A mucosal vaccine prevents eosinophilic allergic airway inflammation by modulating immune responses to allergens in a murine model of airway disease
Inhibition of epithelial cell YAP-TEAD/LOX signaling attenuates pulmonary fibrosis in preclinical models
Lung structural cells are altered by infeluenza virus leading to rapid immune protection following re-challenge
Biomarker panels for improved risk prediction and enhanced biological insights in patients with atrial fibrillation
Effects of sacubitril/valsartan on hypertensive heart disease: the REVERSE-LVH randomized phase 2 trial
Integrated multiomics of pressure overload in the human heart prioritizes targets relevant to heart failure
Spatiotemporal HO flashes coordinate actin cytoskeletal remodeling and regulate cell migration and wound healing
Tumour initiated purinergic signalling promotes cardiomyocyte RBFOX1 degradation and cardiotoxicity from DNA damaging anticancer agents
In vivo measurement of an Apelin gradient with a genetically encoded APLNR conformation biosensor
Cardiomyocyte OTUD1 drives diabetic cardiomyopathy via directly deubiquitinating AMPKα2 and inducing mitochondrial dysfunction
Scavenger receptor CD163 multimerises to allow uptake of diverse ligands
Inhibiting CD36 palmitoylation improves cardiac function post-infarction by regulating lipid metabolic homeostasis and autophagy
Chromatin interaction maps of human arterioles reveal mechanisms for the genetic regulation of blood pressure
Colchicine in patients with aortic stenosis undergoing transcatheter aortic valve replacement: a double-blind randomized trial
A programmable platelet theranostic platform for adaptive multi-stage delivery and synergistic immunotherapy in atherosclerosis
Cross-population GWAS and proteomics improve risk prediction and reveal mechanisms in atrial fibrillation
Connective tissue disorder and high risk pregnancy: a case series with personalised external aortic root support (PEARS)
Immature Acta2R179C/+ smooth muscle cells cause moyamoya-like cerebrovascular lesions in mice prevented by boosting OXPHOS
Imbalanced TGFβ signalling and autophagy drive erythroid priming of hematopoietic stem cells in β-thalassemia
Mitophagy mitigates mitochondrial fatty acid β-oxidation deficient cardiomyopathy
Levosimendan for postoperative subclinical heart failure after noncardiac surgery: a randomized, double-blinded, phase III trial
Multiplexed self-adaptable Janus hydrogels rescue epithelial malfunction to promote complete trachea repair
Association between self-reported multimorbidity and longitudinal brain Aβ deposition in Alzheimer’s disease
Stress granule assembly impairs macrophage efferocytosis to aggravate allergic rhinitis in mice
PI3Kγ signaling controls trafficking of CD8+ T cells between lymphoid and non-lymphoid organs and drives hypertension in a murine model
Normothermic human kidney preservation drives iron accumulation and ferroptosis
Phage therapy with nebulized cocktail BX004-A for chronic infections in cystic fibrosis: a randomized first-in-human trial
2
Aberrant cellular communities underlying disease heterogeneity in chronic obstructive pulmonary disease
Multi-modal spatial characterization of tumor immune microenvironments identifies targetable inflammatory niches in diffuse large B cell lymphoma
2
Regulatory factor X 7 limits Myc activity during B cell activation and suppresses Myc-dependent lymphomagenesis
Blood vessel-resident macrophages safeguard blood and vessel integrity in zebrafish
32
Effects of SGLT2 inhibition on incident heart failure in carriers of cardiomyopathy-associated genetic variants
AAV gene therapy for homozygous familial hypercholesterolemia: a phase 1 trial
Low-dose digoxin in patients with heart failure with reduced or mildly reduced ejection fraction: a randomized controlled trial
The microRNA inhibitor CDR132L in patients with reduced left ventricular ejection fraction after myocardial infarction: a randomized phase 2 trial
Predicting referral need for febrile children in low-resource community settings in South and Southeast Asia
Zodasiran for cholesterol and triglyceride lowering in patients with hyperlipidemia: final report of phase 1 basket trial
Benralizumab versus placebo for hypereosinophilic syndrome: a randomized, placebo-controlled phase 3 trial
The NPR1 agonist antibody XXB750 in heart failure: a phase 2 randomized trial
Remote monitoring of heart failure exacerbations using a smartwatch
Long-term risk of death after tuberculosis diagnosis and treatment
Socioeconomic and energy transition disparities in air pollution-related mortality across Europe
Liquid biopsy for the diagnosis of EBV-positive Burkitt’s lymphoma in endemic areas
In vivo base editing gene therapy for heterozygous familial hypercholesterolemia: a phase 1 trial
Obicetrapib in patients with heterozygous familial hypercholesterolemia: the BROOKLYN randomized clinical trial
Lay community health worker-led care with mobile decision support for uncontrolled hypertension: a cluster-randomized trial
Pulsed Field Conventional Thermal Ablation for Paroxysmal Atrial Fibrillation: 4-Year Outcomes in the Study
An oral, liver-restricted LXR inverse agonist for dyslipidemia: preclinical development and phase 1 trial
Fractional flow reserve-guided percutaneous coronary intervention versus medical therapy for stable coronary artery disease: long-term results of the FAME 2 trial
Tirzepatide on obstructive sleep apnea-related cardiometabolic risk: secondary outcomes of the SURMOUNT-OSA randomized trial
The NOTCH3 extracellular domain is a serum biomarker for pulmonary arterial hypertension
Anti-inflammatory therapy with low-dose IL-2 in acute coronary syndromes: a randomized phase 2 trial
Anticoagulation to prevent ischemic stroke and neurocognitive impairment in atrial fibrillation: the BRAIN-AF randomized clinical trial
Global, regional, and national burden of chronic respiratory diseases and impact of the COVID-19 pandemic, 1990–2023: a Global Burden of Disease study
Multi-omic definition of metabolic obesity through adipose tissue–microbiome interactions
Endotyping-informed therapy for patients with chest pain and no obstructive coronary artery disease: a randomized trial
Cardiovascular outcomes of semaglutide and tirzepatide for patients with type 2 diabetes in clinical practice
Antibody-mediated LOX-1 inhibition in patients with residual inflammation after myocardial infarction: a randomized phase 2 trial
AI-based diagnosis of acute aortic syndrome from noncontrast CT
Comparison of dual therapies for hypertension treatment in India: a randomized clinical trial
Irradiation- and busulfan-free stem cell transplantation in Fanconi anemia using an anti-CD117 antibody: a phase 1b trial
Targeting the angiopoietin-like protein 3/8 complex with a monoclonal antibody in patients with mixed hyperlipidemia: a phase 1 trial
Performance of the American Heart Association’s PREVENT risk score for cardiovascular risk prediction in a multiethnic population
1
Effect of climate-driven childhood sleep erosion on potential regional economic inequality
2
Semaglutide and Neovascular Age-Related Macular Degeneration among Adults with Type 2 Diabetes: An Observational Health Data Sciences and Informatics Network Study
NSAID use and the risk of AMD: Insights From a Multi-Center Cohort Analysis
7
Metabolism fine tuning and cardiokines secretion represent adaptative responses of the heart to High Fat and High Sugar Diets in flies
Cholinergic signaling modulates intestinal pathophysiology in a drosophila model of cystic fibrosis
ASNA1 is essential for cardiac development and function by regulating tail-anchored protein stability and vesicular transport in cardiomyocytes
Genome-wide analysis identifies susceptibility loci for heart failure and nonischemic cardiomyopathy subtype in the East Asian populations
Anthracyclines induce global changes in cardiomyocyte chromatin accessibility that overlap with cardiovascular disease loci
MYH11 rare variant augments aortic growth and induces cardiac hypertrophy and heart failure with pressure overload
Novel insights into post-myocardial infarction cardiac remodeling through algorithmic detection of cell-type composition shifts.
10
Cardiovascular outcomes and safety associated with statin therapy for primary prevention in older adults with type 2 diabetes: A target trial emulation study
Comparisons of core component delivery in cardiac rehabilitation programs by country income classification and decade based on the 2025 Global Audit Update: A survey study
Impact of abdominal obesity prevalence trends on dementia, cardiovascular disease, functional impairment, and mortality in older Chinese adults: A Markov scenario simulation, 2020–2050
Early aspirin withdrawal versus dual antiplatelet therapy in high-risk patients after percutaneous coronary intervention: Meta-analysis of randomized trials
Transformer-based deep learning model for real-time prediction of intraoperative hypotension using dynamic time-series vital signs: A retrospective study
Circulating gut microbial metabolites and risk of coronary heart disease: A prospective multi-stage metabolomics study
The impact of the Lancet Commission definition of obesity on its prevalence and implications on long-term cardiovascular-kidney-metabolic outcomes in East Asians: Observational study of two community-based cohorts
NT-proBNP testing for heart failure diagnosis in people with atrial fibrillation: A diagnostic accuracy study
Analysis of inter-hospital transfer on clinical outcomes after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: A secondary analysis of the BRIGHT-4 trial
Absolute risk-based versus individualized benefit approaches for determining statin eligibility in primary prevention of cardiovascular diseases in Chinese populations: A modeling study
40
Thick filament molecular interfaces play a critical role in the pathogenesis of hypertrophic cardiomyopathy
Mathematical modeling of JAK2V617F clonal expansion in a general population cohort
Endothelial c-IAP2 loss amplifies P2X7 receptor-driven inflammation and worsens schistosomiasis-associated pulmonary hypertension
Fluorescence-lifetime optical electrophysiology in contracting cardiomyocytes
Subsarcomeric regulation of thin and thick filaments in skeletal muscle myofibrils
Multiple defects in macrophage antibacterial responses support intracellular survival of Mycobacterium abscessus in cystic fibrosis
Electrical stimulation promotes longevity and regeneration in a colonial chordate
Purine metabolic adaptation protects the endothelium from disturbed flow–induced DNA damage and atherosclerosis
PPP1R3G–RIPK1–ZBP1 axis activates early-stage apoptosis and late-stage necroptosis to promote doxorubicin-induced cardiotoxicity
Immune modulation promotes heart regeneration through macrophage and Granulin functions in medaka
Retinol saturase in the mitochondria antagonizes IDH2 and GLUD1 acetylation to mediate heart repair
Single-molecule dissection of CFTR folding defects and pharmacological rescue
PARP7 protects the lung epithelial barrier from diverse environmental threats
Beta arrestin 1 is a key regulator of pulmonary vascular tone
TRIM21enhances IL-17A signaling and drives autoimmune myocarditis by promoting TRAF3 lysosomaldegradation in cardiac fibroblasts
Spatial control of myosin regulatory light chain phosphorylation modulates cardiac thick filament mechanosensing
RHOA controls oncogenic B cell receptor signaling in aggressive lymphoma
<atl>Chronic and acute modulator treatment restore wild-type-like activity and stability to the primary cystic fibrosis–causing iCFTR/i variant</atl>
Dynamic regulation of receptor-modulated endothelial NADPH oxidases
Calumenin prevents fibroblast senescence and lung aging by promoting vimentin proteostasis
A myosin hypertrophic cardiomyopathy mutation disrupts the super-relaxed state and boosts contractility by enhanced actin attachment
Distinguishing subtypes of endothelial cells in the mouse aorta
Myeloid GPSM1 regulates atherosclerosis progression by governing monocyte and macrophage activation and chemotaxis
Lipid raft proteomics identify endothelial myosin-9 (MYH9) as a regulator of low-density lipoprotein transcytosis and atherosclerosis
Platelets engage mast cells in a bilateral IL-33-driven feed-forward loop
Inequality in air pollution–attributable mortality by income level between and within countries
Soluble guanylyl cyclase, the NO receptor, drives vasorelaxation via endothelial S-nitrosation
Enhanced PIEZO1 function contributes to the pathogenesis of sickle cell disease
S-nitrosylation of pVHL regulates β2 adrenergic receptor function
3D cryoimaging of cell-mediated cholesterol crystal clearance in human atherosclerotic lesions
PD-1 expression identifies proliferating malignant CLL B cells and is a potential biomarker of response to BTK inhibitor therapy
A FRET assay to monitor different structural states of human β-cardiac myosin including the interacting-heads motif
Danicamtiv reduces myosin’s working stroke but activates the thin filament by accelerating actomyosin attachment
Nitric oxide promotes cysteine N-degron proteolysis through control of oxygen availability
Remote analysis and management of sweat biomarkers using a wearable microfluidic sticker in adult cystic fibrosis patients
Serum metabolic patterns reveal the diagnostic and prognostic role of alanine abnormality in ocular adnexal lymphoma
Wireless arm-worn bioimpedance sensor for continuous assessment of whole-body hydration
Cilia dynamics create a dynamic barrier to penetration of the periciliary layer in human airway epithelia
Resolving the structure and dynamics of the disordered C terminus of human cardiac troponin T and effects of cardiomyopathic mutations
The highly conserved C-terminal end segment of troponin T binds tropomyosin and actin to function in modulating contractile kinetics
17
AI-based Histologic Heterogeneity of Microvascular Obstruction at Cardiac MRI for Predicting MACEs: A Multicenter Study.
Novel Dynamic Chest Radiography Technique for Assessing Pulmonary Regurgitation in Repaired Tetralogy of Fallot.
A Fully Automated Deep Learning Model for Quantifying Coronary Plaque at Coronary CT Angiography.
CT Emphysema and Deep Learning-derived Vertebral Bone Loss in Individuals without COPD: Findings from MESA.
Evaluation of Supracardiac Atherosclerosis in Stroke with a Noncontrast Head-Neck-Aortic Vessel Wall MRI.
Association of CT Features with Radiologic Patterns in Interstitial Lung Disease: Multinomial Analysis in CARE-PF.
Radiologic Pattern of Fibrosis in Combined Pulmonary Fibrosis and Emphysema: Impact on Disease Trajectories and Prognostic Outcomes.
Machine Learning Using Clinical and Cardiac MRI Features to Predict Long-term Outcomes in Acute STEMI.
Super-Resolution Deep Learning Reconstruction for Coronary CT Angiography: Coronary Stenosis Assessment and CAD-RADS Reclassification.
Drug-coated Balloon for Endovascular Treatment of Symptomatic Intracranial Stenotic Disease: A Multicenter Randomized Controlled Trial.
Dynamic Chest Radiography as an Alternative to Pulmonary Function Tests for Chronic Obstructive Pulmonary Disease.
Seven-year Prognostic Value of Coronary CT Angiography-derived Fractional Flow Reserve in Stable Angina.
Left Atrial Minimum Volume Index at Cardiac MRI Predicts Adverse Outcomes after Acute Myocardial Infarction.
Emphysema at Baseline Low-Dose CT Lung Cancer Screening Predicts Death from Chronic Obstructive Pulmonary Disease and Cardiovascular Disease Up to 25 Years Later.
ELCAP Coronary Artery Calcium Score at Lung Cancer Screening CT Predicts Up to 25-Year Mortality.
Left-to-Right Chamber Volume Ratios at Cardiac MRI Predict Cardiac Events: A Multi-Ethnic Study of Atherosclerosis Secondary Analysis.
Longitudinal Tracking of Emphysema Holes at Noncontrast CT: Dynamic Patterns and Clinical Relationships.
5
Severe obesity in human HFpEF alters contractile protein function and organization
Targeting modulated vascular smooth muscle cells in atherosclerosis via FAP-directed immunotherapy
Deep-learning analysis of 3D microarchitectural remodeling in hypertrophic cardiomyopathy
Preventing hypocontractility-induced fibroblast expansion alleviates dilated cardiomyopathy
Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia
29
Statins promote muscle metabolic danger and NLRP3-mediated myopathy via lower protein-prenylation and YAP
PM2.5 air pollution inequities in the US by sector and state: Past trajectories and future directions
The ligand preference of LRP1 is regulated by O-glycans
Noninvasive optogenetic induction of cardiac arrhythmias alters systemic hemodynamics in mice
EZH2 inhibition via GSK-126 mitigates EndMT and atherosclerosis in diabetes: A translational epigenetic approach
The pleuroparenchymal fibroelastosis atlas reveals aberrant cell states and their zonation as an alternate roadmap to lung fibrosis
Mavacamten inhibits myosin activity by stabilizing the myosin interacting-heads motif and stalling motor force generation
Cryo-EM reveals how cardiomyopathy therapeutic drugs modulate the myosin motors of the heart
Regulation of sodium/calcium homeostasis by BacNav gene therapy rescues cardiac dysfunction in chronic heart failure
A beneficial environment promotes immune resilience through epigenetic regulation
Structure and dynamics of a multidomain nitric oxide synthase regulated by a C2 domain
Design and preclinical feasibility of a pediatric heart valve stent that spontaneously adapts to growth via a spring mechanism
PARP1 stabilizes FOXN3 to suppress pulmonary fibrosis through p38-related feedback regulation
The mechanism of action of digoxin requires the sodium-dependent inactivation of the sodium-calcium exchanger
Topoisomerase III-beta protects from immune dysregulation and tumorigenesis
An ultrasmall theranostic nanozyme for abdominal aortic aneurysm management and therapeutic efficacy monitoring
Metabolic reprogramming in Fanconi anemia: Evidence of compromised glucose oxidation, enhanced ketogenesis, and metabolic inflexibility
Selective AMPKβ1 activation induces fetal hemoglobin in human erythroid cells and sickle cell mice via the noncanonical NRF2 pathway
PIEZO1 gain-of-function mutation drives cardiomyopathy by disrupting myocardial lipid homeostasis besides iron overload
AIBP-LRP2–mediated HDL uptake restricts CXCR4+ stemlike capillary expansion and collateral circulation
How sighing regulates pulmonary surfactant structure and its role in breathing mechanics
CLL to Richter syndrome: Integrating network strategies with experiments elucidating disease drivers and personalized therapies
Mitochondrial ROS drive foam cell formation via STAT5 signaling in atherosclerosis
Transcriptome fingerprinting of aberrant fibroblast activation unlocks effective therapeutics to tackle cardiac fibrosis
Simultaneous imaging of bidirectional guided waves probes arterial mechanical anisotropy, blood pressure, and stress synchronously
Biomimetic targeted self-adaptive nanodrug for inflammation optimization and AT2 cell modulation in precise ARDS therapy
Atopy-related immune profiles are subject to genetic influence as evaluated using school-aged twin pairs
NLRP3 inflammasome–driven hemophagocytic lymphohistiocytosis occurs independent of IL-1β and IL-18 and is targetable by BET inhibitors
BRD4770 protects against DOX-induced cardiotoxicity by inhibiting apoptosis and ferroptosis
17
Toll-like receptor 5 protects against murine lung fibrosis through reduced dysbiosis, and TLR5 deficiency is associated with human IPF
CCR5 and CD74 are potential therapeutic targets for necroinflammation in preclinical cholesterol crystal embolism
Sotatercept reduces bone morphogenetic protein signaling in patients with pulmonary arterial hypertension
Natural killer cell immunotherapy reverses lung fibrosis by eliminating senescent fibroblasts
Lactate transport inhibition therapeutically reprograms fibroblast metabolism in experimental pulmonary fibrosis
Diabetes-induced TREM2–endothelial cell signaling impairs ischemic vascular repair
Functional correction of the untreatable CFTR 1717-1G>A mutation through mRNA- and sgRNA-optimized base editing
Selective translation of ZNF281 as part of the integrated stress response system has therapeutic relevance for cardio-oncology
Chaperone-mediated autophagy supports organ regeneration and fibroblast quiescence in mouse models of fibrosis
Sine oculis homeobox 1 drives endothelial dysfunction in preclinical pulmonary arterial hypertension
Extracellular BRICK1 drives heart repair after myocardial infarction in mice
Inhibition of CXCL10 and IFN-γ ameliorates myocarditis in preclinical models of SARS-CoV-2 mRNA vaccination
Dysregulated alveolar type 2 epithelial cell proteostasis promotes fibrogenic macrophage migration inhibitory factor–CD74 signaling
The IL-33 and IL-4Rα blocking antibodies itepekimab and dupilumab modulate both distinct and common inflammatory mediators in asthma
Engraftment and persistence of HBB base-edited hematopoietic stem cells in nonhuman primates
Complement is activated in patients with acute chest syndrome caused by sickle cell disease and represents a therapeutic target
Regulatory T cells attenuate chronic inflammation and cardiac fibrosis in hypertrophic cardiomyopathy
1
Developing a Population-Density-Weighted Community Health Vulnerability Index for Heat and Air Quality to Support Targeted Public Health Interventions: A Multihazard Assessment Using Remotely Sensed and Socio-economic Data in Los Angeles
7
Efficacy of dual antiplatelet therapy for three months versus 12 months after coronary artery bypass grafting: multicentre, double blinded, randomised controlled trial
Prognostic score for predicting respiratory admissions among patients with chronic obstructive pulmonary disease in primary care: development and validation in population cohorts (Birmingham Lung Improvement Studies (BLISS))
Impact of shifting blood donation policy from gift to honour model: staggered difference-in-differences analysis in China
Continued versus discontinued oral anticoagulant treatment for unprovoked venous thromboembolism: target trial emulation
Vernakalant versus procainamide for rapid cardioversion of patients with acute atrial fibrillation (RAFF4): randomised clinical trial
Risk prediction models for cancer therapy related cardiac dysfunction in patients with cancer and cancer survivors: systematic review and meta-analysis
Sex related differences in efficacy and safety of antithrombotic therapy in patients with coronary artery disease: systematic review and meta-analysis
4
Prothrombinase processivity is conferred by substrate allostery
Plakoglobin transmits tension across VE-cadherin for vascular leak formation and leukocyte diapedesis
TRPML1 suppresses pulmonary fibrosis by limiting collagen and elastin deposition
A fibroblast-like endothelial cell state promotes atherosclerosis via C/EBPβ-activated TGF-β signaling
1
Olsenella scatoligenes-derived skatole promotes smooth muscle cell proliferation and migration to aggravate atherosclerosis
35
The SPRR2A–CSTA Axis Drives IL-17A–Induced Squamous Metaplasia and Steroid Resistance in Allergic Rhinitis
Antigen-Specific mRNA–LNP Therapy with mTOR Inhibition Promotes Treg Cells and Limits Allergy
One-year clinical remission with tezepelumab in severe asthma: TERESA single-arm prospective study
Early life peanut oral immunotherapy associated with long-term ingestion and immunologic changes
Characterizing the Nasal Microbiome Using a Nasal Allergen Challenge Model
Associations of rurality, child opportunity, and distance with use of pediatric asthma specialists
Predicting Asthma Prevalence Across U.S. Communities by Integrating Social Vulnerability and Environmental Risk with Machine Learning
Machine Learning Prediction of Asthma and Allergic Rhinitis in Children with Early-Onset Atopic Dermatitis
Avapritinib achieves long-term disease control with favorable safety in patients with indolent systemic mastocytosis over 3 years
Blood neutrophil genetics highlight the role of neutrophils in early childhood asthma and viral respiratory illnesses
Personal network inference identifies children at risk of recurrent wheezing and asthma
Context-specific genetic effects inform endotypes and treatment in asthma
Differential effects of subcutaneous and sublingual immunotherapy on timothy grass–specific TH2 CD4+ T-cell subsets
IL-33 enhances responsiveness and mast cell mediator release in isolated human small airways
Eosinophilic chronic rhinosinusitis with nasal polyps: Squamous metaplasia as an associated remodeling feature
PrecISE—a biomarker-stratified adaptive trial of 5 interventions in severe asthma: Final protocol and the baseline cohort
Club Cell RhoA Activation Amplifies Allergic Airway Inflammation by Regulating Epithelial Integrity and C1qα+ Interstitial Macrophages
Age-Dependent Differences in Airway Inflammation and Function in Severe Uncontrolled Asthma
Platelet-macrophage cooperation drives IL-33-dependent type 2 lung immunopathology in a sex-biased manner
Nasal gene expression shows a distinct signature in T2-high asthma but not in T2-low disease
Dominance of IL-5 and CCL17 in Nasal Cytokine Profiles of Children with Type 2 Inflammation
Disparities in Asthma Control and Treatment: A Spotlight on Mexican American Children
Radical-induced Lipid Oxidation Produces a Torrent of Leukotriene-like Agonists in Severe Asthma
Cendakimab (Anti–IL-13) administration improves esophageal gene expression in eosinophilic esophagitis
The role of CC16 in the associations of preterm birth with lung function and asthma in adult life
Brg1-imprinted chromatin status controls the effector and memory ILC2 metabolism to exacerbate allergic lung inflammation
Reduced ALDH2 in the respiratory tract associates with dysregulated alcohol metabolism and respiratory reactions in AERD
Artificial intelligence biomarker detects high-risk childhood asthma subgroup for respiratory infections and exacerbations
Genetic characterization of preschool wheeze phenotypes
Neighborhood disadvantage and the back-to-school epidemic of viral-associated asthma exacerbations
Cockroach immunotherapy modulates dominant T cell responses independent of allergen extract content
Impact of Nasal and Inhaled Corticosteroids on SARS-CoV-2 Infection Susceptibility
Single cell transcriptomic profiling of eosinophils and airway immune cells in childhood asthma
Identification of potential transcriptomic and microRNA markers to assess benralizumab effectiveness
Analysis of airway inflammation demonstrates a mechanism for T2-biologic failure in asthma
29
Safety, pharmacokinetics, and exploratory efficacy of the oral ghrelin receptor agonist AC01 in heart failure with reduced ejection fraction (GOAL-HF1): a randomised, double-blind, placebo-controlled, phase 1b/2a study
Ticagrelor with aspirin dual antiplatelet therapy combined with intravenous thrombolysis in patients with ischaemic stroke in China (TAPIS): a multicentre, double-blind, randomised controlled trial
Percutaneous coronary intervention versus coronary artery bypass grafting for unprotected left main stenosis: 10-year final results from the randomised, open-label, non-inferiority NOBLE trial
Deferral of percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation (PRO-TAVI): an investigator-initiated, multicentre, open-label, non-inferiority, randomised controlled trial
Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention: 10-year follow-up of the HOST-EXAM trial
Angiography-derived fractional flow reserve versus coronary angiography to guide coronary artery bypass grafting in patients undergoing surgical valve procedures with concomitant coronary artery disease in China (FAVOR IV-QVAS): a multicentre, triple-blind, randomised trial
Prediction of mortality, bleeding, and ischaemic events in patients with cancer and acute coronary syndrome: a model development and validation study
Abluminus DES+ sirolimus-eluting stent versus everolimus-eluting stent in patients with diabetes and coronary artery disease (ABILITY Diabetes Global): results from a multicentre, randomised controlled trial
Epcoritamab, lenalidomide, and rituximab versus lenalidomide and rituximab for relapsed or refractory follicular lymphoma (EPCORE FL-1): a global, open-label, randomised, phase 3 trial
Tafasitamab, lenalidomide, and rituximab in relapsed or refractory follicular lymphoma (inMIND): a global, phase 3, randomised controlled trial
Transcatheter aortic valve implantation with the Trilogy valve for symptomatic native aortic regurgitation (ALIGN-AR): a pivotal, multicentre, single-arm, investigational device exemption study
Complete versus culprit lesion-only revascularisation for acute myocardial infarction (Complete Revascularisation Trialists' Collaboration): an individual patient data meta-analysis of randomised trials
Percutaneous transcatheter valve replacement in individuals with mitral regurgitation unsuitable for surgery or transcatheter edge-to-edge repair: a prospective, multicountry, single-arm trial
Dual antiplatelet therapy after percutaneous coronary intervention according to bleeding risk (HOST-BR): an open-label, multicentre, randomised clinical trial
Sultiame once per day in obstructive sleep apnoea (FLOW): a multicentre, randomised, double-blind, placebo-controlled, dose-finding, phase 2 trial
Ibrutinib and rituximab versus immunochemotherapy in patients with previously untreated mantle cell lymphoma (ENRICH): a randomised, open-label, phase 2/3 superiority trial
Budesonide–formoterol versus salbutamol as reliever therapy in children with mild asthma (CARE): a 52-week, open-label, multicentre, superiority, randomised controlled trial
Effect of evolocumab on saphenous vein graft patency after coronary artery bypass surgery (NEWTON-CABG CardioLink-5): an international, randomised, double-blind, placebo-controlled trial
Paclitaxel-coated versus uncoated devices for infrainguinal endovascular revascularisation in chronic limb-threatening ischaemia (SWEDEPAD 1): a multicentre, participant-masked, registry-based, randomised controlled trial
Benefit–harm trade-offs of intensive blood pressure control versus standard blood pressure control on cardiovascular and renal outcomes: an individual participant data analysis of randomised controlled trials
Paclitaxel-coated versus uncoated devices for infrainguinal endovascular revascularisation in patients with intermittent claudication (SWEDEPAD 2): a multicentre, participant-masked, registry-based, randomised controlled trial
Clopidogrel versus aspirin for secondary prevention of coronary artery disease: a systematic review and individual patient data meta-analysis
Immediate versus staged complete revascularisation during index admission in patients with ST-segment elevation myocardial infarction and multivessel disease (OPTION–STEMI): a multicentre, non-inferiority, open-label, randomised trial
Vericiguat in patients with chronic heart failure and reduced ejection fraction (VICTOR): a double-blind, placebo-controlled, randomised, phase 3 trial
β blockers after myocardial infarction with mildly reduced ejection fraction: an individual patient data meta-analysis of randomised controlled trials
Vericiguat for patients with heart failure and reduced ejection fraction across the risk spectrum: an individual participant data analysis of the VICTORIA and VICTOR trials
Blood pressure-lowering efficacy of antihypertensive drugs and their combinations: a systematic review and meta-analysis of randomised, double-blind, placebo-controlled trials
Spironolactone in patients on chronic haemodialysis at high risk of adverse cardiovascular outcomes (ALCHEMIST): a multicentre, double-blind, randomised, placebo-controlled trial and updated meta-analysis
Spironolactone versus placebo in patients undergoing maintenance dialysis (ACHIEVE): an international, parallel-group, randomised controlled trial
4
Comparison of incidence patterns and risk profiles of ST-elevation and non-ST-elevation myocardial infarction in type 1 diabetes in Finland: a nationwide cohort study
Combined associations of GLP-1 receptor agonists and a healthy lifestyle with cardiovascular outcomes among individuals with type 2 diabetes: a prospective cohort study
Zodasiran, an RNAi therapeutic targeting ANGPTL3, for treating patients with homozygous familial hypercholesterolaemia (GATEWAY): an open-label, randomised, phase 2 trial
Effects of empagliflozin on conventional and exploratory acute and chronic kidney outcomes: an individual participant-level meta-analysis
3
Exploration of the vein to vein blood transfusion system in three Kenyan counties: a qualitative study
Prevalence of non-communicable disease risk factors and chronic conditions among middle-aged and older adults in extreme poverty: a nationally representative cross-sectional study in India
Individual-level and community-level factors for 10-year cardiovascular disease risk in Ethiopia: a retrospective, population-based, cross-sectional, observational study
1
High-sensitivity C-reactive protein, LDL cholesterol, lipoprotein(a) and 30-year risk of stroke in healthy women: a prospective, longitudinal cohort study
1
Pirfenidone for grade 2 and grade 3 radiation-induced lung injury: a multicentre, open-label, randomised, phase 2 trial
50
Exa-cel in Children with Transfusion-Dependent β-Thalassemia or Sickle Cell Disease
In Vivo Base Editing of PCSK9 with VERVE-102 for Hypercholesterolemia
Phase 3 Trials of Inhaled Treprostinil for Idiopathic Pulmonary Fibrosis
Pulsed Field Ablation as Initial Therapy for Persistent Atrial Fibrillation
Three Low-Dose Antihypertensive Agents in a Single Pill after Intracerebral Hemorrhage
Randomized Trial of Adjunctive Prednisolone for Kawasaki Disease
Endovascular Therapy for Post-Thrombotic Syndrome — A Randomized Trial
Multifaceted Strategies for Hypertension Control in Low-Income Patients
CRISPR-Cas12a Gene Editing of HBG1 and HBG2 Promoters to Treat β-Thalassemia
CRISPR-Cas12a Gene Editing of HBG1 and HBG2 Promoters to Treat Sickle Cell Disease
Sirolimus-Coated Balloon Angioplasty for Infrainguinal Artery Disease
Discontinuation of Beta-Blocker Therapy after Myocardial Infarction
Angiography-Derived Fractional Flow Reserve to Guide PCI
Mavacamten in Adolescents with Obstructive Hypertrophic Cardiomyopathy
Angiography-Based Physiology to Guide Coronary Revascularization
Intensive LDL Cholesterol Targeting in Atherosclerotic Cardiovascular Disease
Left Atrial Appendage Closure or Anticoagulation for Atrial Fibrillation
Early Surgery or Conservative Care for Asymptomatic Aortic Stenosis at 10 Years
Left Atrial Appendage Closure or Medical Therapy in Atrial Fibrillation
High-Flow or Standard Oxygen in Acute Hypoxemic Respiratory Failure
Inhaled Treprostinil for Idiopathic Pulmonary Fibrosis
Bleeding Risk with Apixaban vs. Rivaroxaban in Acute Venous Thromboembolism
CD19 CAR T-Cell Therapy for Autoimmune Hemolytic Anemia
Fixed-Duration versus Continuous Treatment for Chronic Lymphocytic Leukemia
Medical Management and Revascularization for Asymptomatic Carotid Stenosis
Beta-Blockers after Myocardial Infarction with Normal Ejection Fraction
Phase 1 Trial of CRISPR-Cas9 Gene Editing Targeting ANGPTL3
Therapy for Atrial Fibrillation in Patients with Drug-Eluting Stents
Evolocumab in Patients without a Previous Myocardial Infarction or Stroke
Antithrombotic Therapy after Successful Catheter Ablation for Atrial Fibrillation
A Pragmatic Trial of Glucocorticoids for Community-Acquired Pneumonia
Immediate or Deferred Nonculprit-Lesion PCI in Myocardial Infarction
Transcatheter or Surgical Aortic-Valve Replacement in Low-Risk Patients at 7 Years
Sotatercept for Pulmonary Arterial Hypertension within the First Year after Diagnosis
Hypertonic Saline or Carbocisteine in Bronchiectasis
Ticagrelor and Aspirin or Aspirin Alone after Coronary Surgery for Acute Coronary Syndrome
Home-Based Care for Hypertension in Rural South Africa
Early Withdrawal of Aspirin after PCI in Acute Coronary Syndromes
Early Discontinuation of Aspirin after PCI in Low-Risk Acute Myocardial Infarction
Aspirin in Patients with Chronic Coronary Syndrome Receiving Oral Anticoagulation
Beta-Blockers after Myocardial Infarction in Patients without Heart Failure
Aficamten or Metoprolol Monotherapy for Obstructive Hypertrophic Cardiomyopathy
Apixaban for Extended Treatment of Provoked Venous Thromboembolism
Mavacamten in Symptomatic Nonobstructive Hypertrophic Cardiomyopathy
Beta-Blockers after Myocardial Infarction without Reduced Ejection Fraction
Multidomain Rehabilitation for Older Patients with Myocardial Infarction
Reduction of Antihypertensive Treatment in Nursing Home Residents
Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction
Phase 3 Trial of Inhaled Molgramostim in Autoimmune Pulmonary Alveolar Proteinosis
Rapid Recovery of Donor Hearts for Transplantation after Circulatory Death
47
The impact of vitamins A and D on lung function and regulatory epigenetics in adult and childhood asthma
Performance of multivariable risk prediction algorithms in predicting COPD exacerbations: a population-based study
Childhood haematological and immunoglobulin trajectories and risk of asthma at 18 years
Trends in asthma incidence and prevalence in 2 million children and adolescents in Catalonia, Spain, 2010–2024: a population-based cohort study
Paediatric bronchiectasis phenotypes and their association with clinical outcomes: development and validation in two prospective clinical cohorts
Survival in congenital central hypoventilation syndrome (CCHS): data from the European CCHS Consortium
Oxygen-enhanced MRI and multiple breath washout with Short extension reveal cystic fibrosis lung disease progression despite triple modulator therapy
Circulating CTHRC1 levels are associated with IPF disease severity and survival
Occupational inhaled exposures and risk of interstitial lung abnormalities in individuals with potential familial susceptibility to pulmonary fibrosis
Association of blood eosinophils and exhaled nitric oxide with exacerbations in patients with asthma, COPD and asthma+COPD: the NOVELTY study
At-risk registers integrated into primary care to stop asthma crises in the UK: cluster randomised controlled trial with economic evaluation
Association between overuse of short-acting β2-agonists and the risk of major adverse cardiovascular events among patients with asthma
Correlates of 5-year decline in 6-min walk distance in the COPDGene cohort
Altitude-induced periodic breathing optimises respiratory efficiency during sleep in young healthy males
Clinical and cost-effectiveness of SPACE for COPD delivered as a pulmonary rehabilitation maintenance programme: a randomised controlled trial
Atomoxetine plus oxybutynin for obstructive sleep apnoea: a randomised-controlled trial with detailed pathophysiology
Comparison of Lower Airway Sampling Strategies in Children with Protracted Bacterial Bronchitis (CLASSIC-PBB): a non-randomised, internally controlled, multicentre trial
Short-term effects of size-fractioned particulate matter on blood pressure in patients with COPD: the key role of inflammatory phenotypes
Development and validation of the Hypersensitivity Pneumonitis South Asian Questionnaire for Exposure (HP-SAQE): a novel, qualitative and quantitative tool
Acetazolamide to prevent ventilatory drive withdrawal in REM sleep apnoea: a randomised controlled trial
Loop gain predicts residual sleep apnoea among people using positive airway pressure
Transcriptomic signatures of IPF in ALI-cultured airway cells and their therapeutic implications
Clinical, molecular and microbial characterisation of the eosinophilic endotype of bronchiectasis: data from the EMBARC-BRIDGE study
Incidence and prevalence of obstructive sleep apnoea and narcolepsy in the UK: a population-based descriptive study
Extreme value analysis has the potential to improve spirometry interpretation
Impact of air pollution on lung function in cystic fibrosis over a decade in London: a UK CF Registry study
Clinical impact of customised positive airway pressure (PAP) therapy interfaces (3DPiPPIn): a single site randomised controlled trial
Antifibrotic therapy and lung cancer risk in patients with idiopathic pulmonary fibrosis: a large retrospective propensity-weighted cohort study
Elastic parametric response mapping: quantitative CT scoring for local COPD severity
Development and validation of PRECISE-X model: predicting first severe exacerbation in COPD
Disproportionate increase in COPD exacerbation risk for 3 months after discontinuing LAMA or ICS: insights from the FLAME trial
Heterogeneity of short-term elexacaftor-tezacaftor-ivacaftor response in cystic fibrosis using 129Xe MRI
Blood eosinophil-guided systemic corticosteroid duration in adults hospitalised for asthma exacerbation: a randomised, controlled, open-label, non-inferiority trial
Multidisciplinary, non-pharmacological breathlessness intervention service for patients with moderately severe to severe COPD: a randomised controlled trial
Disproportionate impairment in diffusing capacity predicts pulmonary hypertension with an elevated pulmonary vascular resistance in COPD
Understanding the bidirectional relationship between chronic respiratory disease and cardiovascular disease using genetic evidence
Sex differences in outcome after endoscopic lung volume reduction (ELVR) in patients with emphysema: a retrospective analysis of the German Lung Emphysema Registry (LER e.V.)
Time to diagnosis and long-term outcomes for adults presenting with breathlessness
Safety, feasibility and efficacy of exercise as an airway clearance technique in cystic fibrosis: a randomised pilot feasibility trial
Proteomics-based risk prediction and drug targets identification for chronic obstructive pulmonary disease
Mobile health pulmonary rehabilitation (m-PR): a randomised controlled equivalence trial
Acute breathlessness as a cause of hospitalisation in Malawi: a prospective, patient-centred study to evaluate causes and outcomes
Adherence to the EAT-Lancet diet, plasma proteomics and the risk of chronic obstructive pulmonary disease
Serum IgA isotypes are associated with percent emphysema, wall thickness and lung function decline
Factors associated with guideline-concordant maintenance inhaled medication for COPD: a population-based, longitudinal cohort study
Efficacy and safety of novel airway balloon cryoablation system for malignant central airway obstruction: a prospective, multicentre, randomised, non-inferiority study
Effect of simvastatin on postoperative complications in patients undergoing one-lung ventilation during surgery: the Prevention HARP-2 randomised controlled trial

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