Neurosciences articles

Time frame: 1 May 2025 - 30 April 2026

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Count: 1444

Article ‘Count’ for Neurosciences.

Journal Count
25
Neuroimmune-Metabolic Regulation by a Wireless Biodegradable Neuromodulator for Cardiovascular Therapy in a Mouse Model
Chloroplast-Inspired Nanoassemblies for Ischemic Stroke Therapy: Cross-Kingdom Recoupling with Mitochondrial Metabolism
Probiotic Spore-Based Oral Biotherapeutics Promote Brain Targeting toward Gut-Brain Dual-Regulation for Parkinson’s Disease Treatment
Bioinspired Multilayered Conductive Nerve Guidance Conduit Built on Hydrogels and Knitted Silk Fiber Sleeves for Peripheral Nerve Regeneration
A Preventable Alzheimer’s Disease Microneedle Patch with Synaptic Protection and NLRP3 Inflammasome Suppression in Microglia during Smoking Cessation
Neonatal Spinal-Cord-Like Scaffold with Hierarchical Structural and Neurogenetic Microenvironments for Spinal Cord Injury Repair
Amphiphilic Ebselen Conjugate Suppresses Tripartite Motif-Containing 21-Glutathione Peroxidase 4 Axis-Dependent Neuronal Ferroptosis and Ameliorates Epilepsy
Meningeal Lymphatic System-Driven Nanodelivery Unlocks Ursolic Acid’s Pleiotropic Benefits To Optimize Multiple Sclerosis Treatment
Rabies Virus Glycoprotein-Decorated Liposomes in Thermosensitive Nasal Spray Gels: Facilitating Retrograde Neural Transport for Targeted Trigeminal Neuralgia Therapy
Small Gold Nanoparticles Alleviate Huntington’s Disease via Modulating p38α Mitogen-Activated Protein Kinase and Pyruvate Dehydrogenase Kinase 1
Piezo1-Targeted Magnetoacoustic Nanobubbles Rescue Alzheimer’s Pathology by Electromechanical Neuromodulation and Amyloid-β Clearance
An Autophagy-Sensitive Nanoplatform via Chirality-Selective Modulation for Functional Peripheral Nerve Repair and Target Organ Homeostasis
Modulating Amyloid Pathology–Neural Hyperexcitability Crosstalk for Alzheimer’s Disease Therapy
Unlocking Neuroprotection: Simultaneous Suppression of Mitochondrial Energetic Collapse and Oxidative-Inflammatory Vortex for Ischemia-Reperfusion Brain Injury
Piezo-Nanowired Stem Cells: Ultrasound-Powered Neuronal Commitment for Rapid Neural Circuit Reconstruction after Traumatic Brain Injury
Engineering Near-Infrared-II Nanoprobes Reveal Dexmedetomidine Potentiating Brain Waste Clearance in Healthy and Sleep-Restricted Mice
Hybrid Exosome–Liposome Nanoparticles for Dual Modulation of Neuroinflammation and Lipid Metabolism in Ischemic Stroke
Biomimetic Nanoregulators Mediated Tyrosine Hydroxylase mRNA and Stimulator of Interferon Genes Antagonist Codelivery for Synergistic Therapy on Parkinson’s Disease
Single-vesicle Tracking of α-Synuclein Oligomers Reveals Pore Formation by a Three-Stage Model
An Implant-Free Nanosystem Enabling Synergistic Oxidative Damage Mitigation and Deep Brain Stimulation for Alleviating Parkinsonian Symptoms
Enhancing Thrombolysis Safety in Post-Acute Ischemic Stroke with Tissue Plasminogen Activator-Associated Microparticles
Inflammatory Oriented Nanospheres-Reconstructed Extracellular Matrix in Ischemic Stroke
Triple-Cue-Guided Multichannel Hydrogel Conduit to Synergistically Enhance Peripheral Nerve Repair
Mesenchymal Stem Cell-Derived Mitochondrial Transfer Promotes Tip Cell Phenotype via Glutathione Metabolic Reprogramming in Stroke Mice
Inhibiting Immune Crosstalk by Modulation of the Intracellular Function and Extracellular Environment of Diseased Microglia to Boost Parkinson’s Disease Therapy
16
Stiffness-Engineered Hydrogels Drive Neural Regeneration via the Man2b1– Lysosomal Mechanotransduction Axis
Cryo-shocked Neural Stem Cells as Factor Pool-Functionalized Nerve Guidance Conduits for Enhanced Peripheral Nerve Regeneration
Subarachnoid Trabeculae Suppress Cerebrospinal Fluid Pressurization During Translational Impact Loading using Instrumented Biomimetic Head Surrogates
Peptide Concentration Gradients and Aligned Microfiber Topography Synergize to Speed and Direct Schwann Cell Migration
Lipid nanoparticle-mediated Cd14 siRNA delivery ameliorates the acute inflammatory response to intracortical microelectrode implantation
Electrowritten Topographical Conduit Integrated with 4-Octyl Itaconate for Peripheral Nerve Immunomodulation and Regeneration
Microenvironment-modulating hyaluronic acid-tannic acid hydrogel for peripheral nerve injury repair
Reactive Oxygen Species-Responsive Sulfated Polysaccharide-Based Nanogels for Ischemic Stroke: A Precision Therapy through Pathological Microenvironment Modulation
Lipid nanoparticles hijack neutrophils for enhanced anti-inflammatory and stroke therapy
Super-small zwitterionic nitric oxide-donor micelles efficiently scavenge ROS and alleviate inflammation for combined ischemic stroke therapy
Microstructural damage progression in the pia-arachnoid complex
Discoidal nanoparticles exploit thrombus-induced shear gradients to enhance site-specific thrombolysis in stroke
Characterising epi-perineurial barrier function by microscale techniques including a miniaturised Ussing chamber
Platelet membrane-camouflaged bioactive glass nano-formulations for enhanced drug delivery in the treatment of acute arterial thrombosis
Hydrogel system with growth cone-targeted hydroxyapatite nanorods: Regulating calcium signals for peripheral nerve injury repair
Repeated loading and damage progression in cerebral arteries
23
Multi‐Scale Oriented PLCL/CNT@a Conduit Filled With Dual‐Sided Micropatterned Filaments Enhanced Peripheral Nerve Regeneration
Engineered Macrophage Microrobots Exert Precise Neuroprotection Against Ischemic Stroke by Regulating the Polarization of Inflammatory Microglia
Immuno-Training Remodeled Vascular Microenvironment via Peptide-Functionalized Hydrogel Microspheres for Neural Repair
Bioinspired Self-Curling Conduit Integrates Topography and Bioelectronics for Functional Peripheral Nerve Regeneration
Bioinspired Artificial Nociceptor Based on Quantized Conductance Memristor With Pain Rating, Self‐Healing, and Neuromodulation Capabilities
Yolk-Shell Nanoparticles with Shear Stress-Triggered Triboluminescence for Dynamic Thrombus Imaging and Tribocatalytic-Photodynamic Thrombolysis
Acid-Responsive Nanomotors Regulate the Crosstalk between Neutrophils Infiltration and Acidosis for the Precise Targeted Treatment of Ischemic Stroke
Dual-Pathway Modulated Biomimetic Conductive Hydrogel Conduit Enables Spatiotemporal Co-Delivery of Engineered C3-Exosomes and TT-10 to Potentiate Optic Nerve Regeneration
A Soft On-Skin Sensor Simultaneously Capturing Bioelectrical and Biomechanical Signals for Muscle Spasticity Detection and Assessment
Mesenchymal Stem Cell-Driven Neurotrophic Bioelectronic Platform (MSC-NBP) Potentiated Peripheral Nerve Regeneration
A Self-Curling Si3N4-Biofunctionalized Nerve Wrap for Suture-Free Peripheral Nerve Repair with Multimodal Regenerative Bioregulation
Ultrasound‐Triggered Biomimetic Piezo‐Nanoplatforms for Non‐Invasive Epilepsy Treatment
Digital Dual-Dimensional α-Synuclein Aggregate Decoding Sensor for Parkinson's Disease Diagnostics
Active Transport of Biomimetic Cascaded Nanozymes Across Blood–Brain Barrier to Scavenge ROS and Alleviate Neuroinflammation Against Cerebral Ischemia Reperfusion Injury
Microenvironment-Responsive Piezoelectric Nanofibers Antagonize Chemotherapy-Induced Peripheral Neuropathy
Surgical‐Adjuvant Hydrogel of Full‐Natural Bioactive Compounds from Chinese Medicine for Enhanced Traumatic Brain Injury Therapy by Inhibiting Complement Activation
Biodegradable Piezoelectric Amino Acid Nerve Guidance Conduit Repairs Long‐Gap Nerve Defect Under Low Frequency Vibration from Massage Gun
Biosponge-Armored Nanodots Restore Redox-Calcium Homeostasis to Mitigate Reperfusion-Induced Injury in Ischemic Stroke
Multiple‐Stimuli‐Responsive Biomimetic Polypyrrole Delivery System for Synergistic Regulation and Restoration of Epileptic Foci
Reconstruction of Joint‐Associated Peripheral Nerve Defects Using Novel Piezoelectric Spiral‐Structured Poly(Lactic Acid) Fiber Conduits: Regeneration Efficacy and Mechanistic Insights
A Janus Mg2+ and H2 Pump Conduit for Enhanced Peripheral Nerve Regeneration
Au Nanowires as Membrane‐Attached Magnetoelectric Nanoelectrodes to Promote Neuronal Differentiation and Spinal Cord Injury Repair
Shear Stress-Triggered Thrombolysis by Yolk–Shell Nanoparticles with Piezoelectric-Tribovoltaic Dynamic Schottky Junctions
17
Elastomeric Micro-Balloons for Remote Control of Cerebral Blood Flow and Real-Time In vivo Imaging of Rodent Brain Response to Hypoperfusion
Oral Magnetoelectric Neuroimmunomodulation via the Gut–Brain–Spleen–Heart Axis for Noninvasive Atrial Fibrillation Therapy
Synthetic Disaggregators Enhance Central-Peripheral Amyloid-β Clearance in Alzheimer's Disease
Poly(Citric Acid) Bidirectional Regulator: Coordinating Iron Homeostasis to Suppress Stress Responses and Boosting Mitochondrial Bioenergetics for Enhanced Nerve Repair
An Injectable and Modular NO‐Adaptive Delivery System for Modulating Regenerative Microenvironment in Long‐Segment Nerve Injury
A Bioinspired Force‐Inducible Hydrogel Conduit for Peripheral Nerve Regeneration
Chiral Nanoagonist Targeting EGFR for Nerve Injury Repair
NIR‐Driven Nanomotors Integrating With Platelet‐Thylakoid Hybrid Membranes for Synchronized Thrombolysis and Vascular Remodeling
Bamboo-Inspired Composite Conduit Accelerates Peripheral Nerve Regeneration through Synergistic Oriented Structure and Piezoelectricity
Multimodal Nanoregulator Rescues Impaired Neurovascular Units to Attenuate Secondary Injury Following Traumatic Brain Injury
NIR‐II Imaging‐Guided Self‐Penetrating Nanomotors for Millimeter‐Scale Deep Thrombolysis Tracking and Accelerated Embolus Clearance
Ultrasound Active Piezoelectric Nanostimulators for Long-Acting Wireless Deep Brain Electric Stimulation to Inhibit Epileptic Seizures
A Universal Strategy for BBB Transport Mediated by an Inflammatory Receptor Antagonist for Neuroprotection in Ischemic Stroke
Wireless Acousto-Piezoelectric Conduit with Aligned Nanofibers for Neural Regeneration
Sonodynamic and Bioorthogonal Sonocatalytic Thrombotic Therapy Based on AIE Cationic Tetranuclear Ir(III) Complex Nanoplatform Guided by NIR‐Chemiluminescence Imaging
Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain
In Situ Magnetoelectric Generation of miRNA Sponges and Wireless Electric Stimulus by Conductive Granular Scaffolds for Nerve Regeneration
2
Migraine, comorbidity, and risks of severe maternal and neonatal morbidity or mortality: a population-based cohort study
Racial Disparities in Incident and Recurrent Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis
2
SMN1 variants identified by false-positive SMA newborn screening tests: Therapeutic hurdles and functional and epidemiological solutions
Landscapes of missense variant impact for human superoxide dismutase 1
1
Can Maternal Metformin Protect the Developing Fetal Brain?
5
Leukocytic Dopamine D2 Receptors as Biomarkers for Brain Dopamine Levels in Parkinson’s Disease
Parenchymal and Dyshoric Fibrillar Amyloid Pathology in the rTg-D Rat Model of Cerebral Amyloid Angiopathy Type-2
Novel Kinesin Family 1A Variants Linked to Atypical Parkinsonism Elicit Altered Neuronal TDP-43 Interactions and Dendritic Atrophy
Distinct Role of Dural and Leptomeningeal Macrophages in Maintaining Cerebrospinal Fluid Drainage to Meningeal Lymphatic Vessels
Autocrine TGF-β signaling promotes cell motility and chemokine secretion in an angiomyolipoma-derived cell model of lymphangioleiomyomatosis
17
Simultaneous Visualization of Glutathione and Hydrogen Peroxide with a Dual-Responsive Fluorescent Probe to Elucidate Redox Homeostasis in Alzheimer’s Disease Models
Peroxynitrite-Activated Valproic Acid Precursor for Monitoring Oxidative Stress and Reducing Epileptic Seizures in an Epilepsy Model
A BBB-on-a-Chip for Ischemic Stroke Modeling: In Situ Multiparameter Monitoring with Integrated TEER and Ion Sensors
Systematic and Quantitative Investigation of Newly Synthesized Proteins Reveals Distinct Ion Homeostasis and Mitochondrial Changes between Cuproptosis and Ferroptosis in Human Cells
Aβ-Targeted Theranostic Agent for NIR Fluorescence Imaging Guided Type-I and Type-II Dual Photodynamic Therapy of Alzheimer’s Disease
Monitoring the Switching from Base-on to Base-off Forms of Vitamin B12 by Natural and Magnetic Circular Dichroism Spectroscopies
O-Position Electronegativity Dependent Activity for Specific-Rapid Response to Superoxide Anion and Its Imaging for Epilepsy Mediated by Ferroptosis Pathway
Investigating the Effect of Oxaliplatin on Vesicular Dopamine Cargo and Release Dynamics in Brain with Single-Vesicle Electrochemistry
Near-Infrared Chemiluminescence Probe for Superoxide Anion Imaging in Alzheimer’s Disease
A Triple-Channel Fluorescent Sensor Array Based on Carbon Dots for Simultaneous Discrimination and Detection of Antiseizure Medications and Psychotropic Drugs in the Treatment of Epilepsy Comorbidities
Rational Construction of a Lipid Droplet-Targeted Redox-Responsive Ratiometric Probe for Screening of Antioxidant Drugs and Its Application in Parkinson’s Disease
In Vivo Solid-Phase Microextraction with Palladium-Doped Covalent Organic Framework-Coated Fiber for Enhanced Nicotine-Associated Metabolite Detection in Rat Brain Regions
Blood-Brain Barrier-Permeable Dual-Responsive Fluorescent Probe Reveals an Increased Risk of Alzheimer’s Disease in Diabetic Patients
A Red-Emitting Fluorescent Probe for Visualizing Hydroxyl Radical in Parkinson’s Disease and Guiding the Discovery of Methyl Ferulate for Therapeutic Intervention
Revealing the Interplay of Intraorganellar O2•– and ATP in Brain Aging-Related Alzheimer’s Disease via Unimolecular Dual-Responsive Probes
Development of Tau-441-Certified Reference Materials by Three Independent Isotope Dilution Mass Spectrometry Strategies
Activatable Proximity-Labeled Fluorogenic Probe for Visualizing the Role of Estrogen in Regulating Liver Carboxylesterase Expression
6
Effects of γ-Aminobutyric Acid and Glutamate Signalings from Primary Sensory Neurons to Gate the Spinal Transmission of Mechanical Pain in Mice.
Modulation of pain sensitivity by the locus coeruleus-paraventricular thalamic nucleus-anterior cingulate cortex pathway in mice.
General anesthesia and systemic hyperosmolality modulate lumbar intrathecal drug distribution in female rats.
Differential Effects of Pregabalin and Morphine on the Sleep-Wake Cycle and Circadian Rhythms in Mice with Neuropathic Pain.
The effects of lacosamide, pregabalin, and tapentadol on peripheral nerve excitability: A randomized, double-blind, placebo-controlled, crossover, multi-center trial in healthy subjects.
Cerebral Blood Flow Under Pressure: Investigating Cerebrovascular Compliance with Phase Contrast Magnetic Resonance Imaging During Induced Hypertension.
11
Ion‐Exchange and Energy‐Stress Strategies Amplified Dual‐Site Nanozyme‐Mediated Ferroptosis/Pyroptosis Inhibition for Neuroprotection
Two-Nanosensor Electrochemical Profiling of Catecholamine Vesicle Interactions With Acute and Chronic Stress Granules in Living Cells
Electrical Sensitive Trianthracene Nanoparticle for Afterglow Imaging Epileptic Abnormal Discharges
Cleavable Antibody‐Conjugated Aβ Specific Immune Exosome for Combination Alzheimer's Disease Immunotherapy
Modeling Midbrain and Brainstem Neuromelanins to Characterize Metal Binding and Associated MRI Contrast in Parkinson's and Alzheimer's Diseases
Magneto‐Luminescence Thermometry with Magnetic Circularly Polarized Luminescence
A Photoregulated Peptidase Mimic
Multiple and Alternative Sites Make Tau Protein an Adaptable Sticky Surface for the SH3 Domain of Fyn Kinase
Thrombus Boring Microrobot Prepared by an Integrated Phase Separation and Interfacial Self‐Assembly Process Toward Thrombolysis
Luminescent Detection of Photomagnetic Effect in a Near‐Infrared Emissive Neodymium(III)–Octacyanidotungstate(IV) Framework
Direct Quantification of Neuroprotective Effect of Single‐Atom Catalyst on Neurochemical Transmission by Multi‐Spatiotemporal Electrochemistry
3
Early Intensive Blood Pressure Reduction After Intracerebral Hemorrhage Is Associated With Worse Functional Outcome: The Risk of Overshooting Blood Pressure Goals
Multiple Health Care Encounters Prior to Diagnosis of Cerebral Venous Thrombosis
Glial Fibrillary Acidic Protein and Ubiquitin C-Terminal Hydrolase L1 for Acute Traumatic Intracranial Lesions: The PIONEER Diagnostic Accuracy Study
1
Action Collaborative on Traumatic Brain Injury Care: Adapted Clinical Practice Guideline
114
The IL-1β-STING Signaling Axis Drives Neuromyelitis Optica Pathogenesis in a Murine Model
Cerebrospinal Fluid Amyloid‐β Biomarkers Predict Future Hemorrhage in Patients with Cerebral Amyloid Angiopathy
Stroke Etiologies With Intravenous Thrombolysis before Thrombectomy and Functional Outcomes in Anterior Circulation Large Vessel Occlusion
Multimodal Image Guidance in Subthalamic Deep Brain Stimulation for Parkinson's Disease
Relapses, Comorbidities, and Predictors of Outcome in Anti-GABAA Receptor Encephalitis
Biochemical and Immunohistochemical Associations of TDP-43 and Cryptic RNA With Hippocampal and Amygdala Volumetrics in Alzheimer's Disease
Hyperreflective Foci in the Inner Nuclear Layer: Proof‐of‐Concept for an Optical Coherence Tomography Derived Microglia‐Related Marker in Multiple Sclerosis
Cerebrospinal Fluid from Restless Legs Syndrome Patients Reduces Iron Uptake in Blood–Brain Barrier Endothelial Cells by Disrupting the Regulation of Transferrin Receptors
Supratentorial Brain Lesions in Unconscious Patients Map to a Common Human Brain Circuit
Network Colocalization Correlates of Depression and Anxiety in Pediatric Focal Cortical Dysplasia‐Related Epilepsy
Effects of Blood Pressure Lowering Across Hematoma Volume in Acute Intracerebral Hemorrhage: Pooled Analysis of the Four INTERACT and ATACH-2 Trials
Functional Segregation of Epileptogenicity within the Human Amygdala
Human Brain Contusions Contain Pathogenic Transmissible Species that Induce Progressive Cognitive Decline and Tau Pathology in Mice
Population‐Based Epidemiology of Autoimmune Seizures and Epilepsies
Gelsolin‐3: A Novel Myelin Autoantigen in Demyelinating Guillain‐Barré Syndrome
Temporal Modeling of Amyloid and Tau Trajectories in Alzheimer's Disease Using PET and Plasma Biomarkers
Increased Numbers of CD4+ T-Cells in the Hypocretin/Orexin Region of Narcolepsy Type 1
Chronological Diagnostic Algorithm Predicting Neuropathology in Parkinsonism
Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics
Predominance of Ferroptotic Cell Death Mechanisms in Substantia Nigra Neurodegeneration in Parkinson's Disease
Distinct Prescription Patterns Emerge Years Before ALS Diagnosis: A Nationwide Registry-Based Study
CSF-Compartmentalized Antibody Glycoprofiles in NMDAR Encephalitis Associate with Etiology and Functional Recovery
The Clinical Spectrum and Neurodevelopmental Pathogenesis of KPTN-Related Disorder in a Mouse Model
Refining Detection of Subclinical Epileptiform Activity in Alzheimer's Disease: A Case–Control Study and Call for a Consensus
Primary Lateral Sclerosis Natural History Study: Primary Lateral Sclerosis Functional Rating Scale and Other Outcomes Assessment
Individualized Atrophy‐Based Prediction of Dementia Progression in Familial Frontotemporal Lobar Degeneration With Bayesian Linear Mixed‐Effects Modeling
Individualized Treatment in Distal and Medium Vessel Occlusion Stroke Using a Validated Explainable Counterfactual Treatment Estimation Model
Severe, Non‐apneic Respiratory Dysfunction and Hypoxia following Generalized Convulsive Seizures
Tau Pathology in Alzheimer's Disease Uniquely Affects Sulcal Depths
Confined B‐Cell Reconstruction and High T‐Cell Clonality Define Clinical Response to Cladribine Treatment
Toward Harmonizing Quantification of Dopamine Neuron Imaging Biomarkers in Parkinson's Disease: The Centamine Scale
Neutrophil-Secreted Enzymes and ALS Risk: Exploring a Potential Mechanistic Link
Novel Aggressive Subtype of Multiple System Atrophy Identified by Unsupervised Machine Learning
Reframing the Risks of Deep Brain Stimulation: A Comparison of 2.8 Million Elective Surgeries From the NSQIP Database
Using Expert‐Cited Features to Detect Leg Dystonia in Cerebral Palsy
<atl>Clinical and Biological Determinants of Longitudinal Cognitive Function in Patients With scp iGBA1/i /scp Variants and Subthalamic Deep Brain Stimulation</atl>
Clot Composition Profiling in Large Vessel Occlusion Stroke Via Radiomics
Probabilistic Lesion Mapping to Optimize Thalamotomy Targets for Focal Hand Dystonia
A Patient‐Derived Antibody Ameliorates Disease Severity in a Relapsing Remitting Murine Model of Multiple Sclerosis
Myelitis‐Predominant Aggressive Phenotype: Unveiling Unique Patterns of Late‐Onset Neuromyelitis Optica Spectrum Disorders
Conditioning Electrical Stimulation for Patients with Moderate or Severe Carpal Tunnel Syndrome: Double Blinded Randomized Controlled Trial
<atl>Effects of Intradural Extension of Extracranial Cervical Artery Dissection on Outcomes: A Secondary Analysis From the scpSTOP/scp ‐ scpCAD/scp Study</atl>
Autonomic Dysfunction and Risk of Mortality in Early‐Onset Parkinson's Disease
Minimally Invasive Surgery Versus Open Craniotomy With Clot Evacuation After Intracerebral Hemorrhage
Age-Related Differences in the Association between REM Sleep and the Polygenic Risk for Parkinson's Disease
The Epidemiology of Primary Lateral Sclerosis: Results from a Population‐Based Cohort
Thrombectomy versus Medical Management for Pediatric Acute Ischemic Stroke Due to Isolated M2 Occlusion: A Multicenter Cohort Study
Aneurysm Wall Enhancement and Probability of Instability in Unruptured Intracranial Aneurysms: A Long‐Term Follow‐Up Study
<atl>Anatomical Progression of Neuropathology in scpFTLD/scp ‐ scpTDP/scp Type C and Linkage to Annexin scpA11/scp</atl>
Tenecteplase Versus Alteplase for First‐Pass Reperfusion in Basilar Artery Occlusion Stroke Thrombectomy
<atl>Timing of Peri‐Ictal scpMRI/scp Abnormalities in Status Epilepticus – One Size Does Not Fit All</atl>
Effects of Thymectomy in Late‐Onset Myasthenia Gravis: A Multi‐Center Longitudinal Retrospective Study
Additive Effects of White Matter Hyperintensity and APOE ε4 Status on Risk of Incident Dementia in Two Large Longitudinal Cohorts
Anatomical Associations Between Focal Mitochondrial Metabolism and Patterns of Neurodegeneration in Amyotrophic Lateral Sclerosis
Thalamic Stimulation Induced Changes in Network Connectivity and Excitability in Epilepsy
Polygenic Vulnerability to Intracranial Hypertension, Hemorrhage Progression, and Outcome in Traumatic Brain Injury
Real‐World Effectiveness of Switching to Oral or Infusion Versus Injectable Disease‐Modifying Therapy in Pediatric Multiple Sclerosis
<atl>Sensorimotor Cortex High Frequency Oscillations Characterize Motor Symptom Severity during scpDeep Brain Stimulation/scp Surgery for Parkinson's Disease</atl>
Detecting Awareness in the Intensive Care Unit Using Functional Near‐Infrared Spectroscopy
Combination of Serum Neurofilament Light Chain and Serum Cardiac Troponin T as Biomarkers Improves Diagnostic Accuracy in Amyotrophic Lateral Sclerosis
Disruption of the Blood–Brain Barrier Predicts Progression of Cerebral Small Vessel Disease White Matter Hyperintensities
Turning Slowly Predicts Future Diagnosis of Parkinson's Disease: A Decade‐Long Longitudinal Analysis
Epstein–Barr Virus, Lower Vitamin D, Low Sun Exposure, and HLA-DRB1*1501 Risk Variant Share Common Epigenetic Pathways Leading to Multiple Sclerosis Onset
Mutations in the Key Autophagy Tethering Factor scpEPG5/scp Link Neurodevelopmental and Neurodegenerative Disorders Including Early‐Onset Parkinsonism
From Diagnosis to Disease Staging: Multisite Validation of Cerebrospinal Fluid Molecular Tests in Multiple Sclerosis
Skeletal Muscle Biomarkers of Amyotrophic Lateral Sclerosis: A Large‐Scale, Multi‐Cohort Proteomic Study
Resilience to Endoplasmic Reticulum Stress Mitigates Membrane Hyperexcitability Underlying Late Disease Onset in a Murine Model of scpSCA6/scp
Dual Antiplatelet Therapy After Ischemic Stroke Stratified by Intracranial or Extracranial Atherosclerotic Stenosis
scpMarkVCID2/scp Consortium for Clinical Validation of Biomarkers of Cerebral Small Vessel Disease: Validation Framework and Baseline Characteristics
Microneurography Reveals Unmyelinated Small Nerve Fiber Dysfunction in Long scpCOVID/scp
Clinical–Radiological Spectrum of Cerebral Amyloid Angiopathy‐Related Inflammation
Behavior Decoding Delineates Seizure Microfeatures and Associated Sudden Death Risks in Mouse Models of Epilepsy
Clinical and Molecular Genetic Characterization of Landau Kleffner Syndrome: An Observational Cohort and Experimental Study
Cuneiform Nucleus Stimulation Can Assist Gait Training to Promote Locomotor Recovery in Individuals With Incomplete Tetraplegia
A Distinct Immunological Signature in Late‐Onset Myasthenia Gravis: Insights from an Exploratory Proteomics Study
Randomized, Double‐Blind, Placebo‐Controlled, Multiple‐Dose Studies to Assess the Safety and Efficacy of Elezanumab when Added to Standard of Care in Relapsing and Progressive Forms of Multiple Sclerosis
Intravenous Glyburide in Medical and Endovascular‐Treated Large‐Core Stroke: A Subgroup Analysis of the scpCHARM/scp Randomized Clinical Trial
Clinical and Cognitive Profiles of Individuals with Alzheimer's Disease and Comorbid Seizures
Uncovering Image‐Driven Subtypes with Distinct Pathology and Clinical Course in Autopsy‐Confirmed Four Repeat Tauopathies
iHCN2/i‐Associated Neurodevelopmental Disorders: Data from Patients and iXenopus/i Cell Models
Visual Features in Stereo‐Electroencephalography to Predict Surgical Outcome: A Multicenter Study
Phenotypic Changes in a Monocyte Cluster with High Interleukin‐1 Beta Expression during Long‐Term Anti‐scpCD20/scp Therapy
Beta Power Response After Levodopa Intake in Parkinson's Disease Patients With Chronic Sensing‐Enabled Deep Brain Stimulation
TARDBP (TDP-43) Knock-in Zebrafish Display a Late-Onset Motor Phenotype and Loss of Large Spinal Cord Motor Neurons
Disease Progression in Multiple System Atrophy: The scpASPIRE/scp Multi‐Modal Biomarker Study
Persisting Transglutaminase 6 Antibodies in Neurological Gluten‐Related Disorders
Brain Endothelial Soluble scpST2/scp Production and Cerebral Edema in a Rat Model of Ischemic Stroke
Behavior‐scpiEEG/scp‐Spectral‐Power‐Correlation: Defining Neural Substrates of Naturalistic Behavior
Adjunctive scpThrombolytics/scp After Successful Endovascular Reperfusion: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
Targeted Proteomics upon Treatment with Tofersen Identifies Novel Response Markers for Superoxide Dismutase 1‐Linked Amyotrophic Lateral Sclerosis
Heart Rate Profiles During Exercise and Incident Parkinson's Disease
Toward a Universal Map of EEG: A Semantic, Low‐Dimensional Manifold for scpEEG/scp Classification, Clustering, and Prognostication
Regional and Global Changes in Brain Structure 1‐Year Post Pediatric “Mild” Traumatic Brain Injury
Frequency of Microvascular Pathology and Hippocampal Atrophy on scpMagnetic Resonance Imaging/scp in a Community Study of Alzheimer's Disease with Blood‐Based Biomarkers
Subthalamic Electrophysiological Mapping of Gait Initiation Dynamics and Freezing in Parkinson's Disease
Sternocleidomastoid Muscle Overactivity: A Potentially Critical Contributor to Postural Abnormalities in Parkinson's Disease
Mapping Postictal Aphasia through Signal Complexity: A Stereo‐Electroencephalography Study
Sex Differences in Associations of Lewy Body Disease with Alzheimer's Disease and Cognitive Decline
Chronic Striatal Cholinergic Interneuron Excitation Causes Cerebral Palsy‐Related Dystonic Behavior in Mice
Clonal Hematopoiesis of Indeterminate Potential Associated with Covert Cerebral Changes
The Role of Electroencephalography in Predicting Post-Stroke Seizures and an Updated Prognostic Model (SeLECT-EEG)
μ‐Opioid Receptor Dynamics in the Parameningeal Tissue During Migraine Attacks
Cortical Excitability as a Prognostic and Phenotypic Stratification Biomarker in Amyotrophic Lateral Sclerosis
High‐Dose Pulse Glucocorticoid Treatment Prevents White Matter Spinal Cord Pseudoatrophy in Newly Diagnosed Multiple Sclerosis
Disease Characteristics and Treatments Associated with Outcome in Primary Angiitis of the scpCentral Nervous System/scp—A Multicenter Cohort Study in 163 Patients
Deep Brain Stimulation for scpiVPS16/i/scp‐Related Dystonia: A Multicenter Study
The FindMNDBiomarker Program: Protein Changes in Motor Neuron Disease/Amyotrophic Lateral Sclerosis Postmortem Tissue and Biofluids
Decoding the Clinical Features that Associate with Progression, Causes, and Outcomes in Patients with Suspected Rapidly Progressive Dementia
Intravenous Thrombolysis Use before Inter‐Facility Transfer for Thrombectomy: Association with Efficacy and Safety Outcomes
The Relationship between Rest Tremor and Underlying Lewy Pathology in Essential Tremor: A Clinical‐Pathological Study of 201 Cases
Blood α‐Synuclein Separates Parkinson's Disease from Dementia with Lewy Bodies
α‐Synuclein‐Related Mitochondria‐Nrf2 Dysfunction in Parkinson's Disease Olfactory Mucosa
Cognitive Outcome in Young Adults after Resolution of Epilepsy in Childhood
Prevalence of Cerebral Amyloid Angiopathy and Associated Risk of Subsequent Ischemic and Hemorrhagic Stroke and Mortality in a Nationwide Cohort
4
Efgartigimod in Sjögren’s disease: a phase 2, randomised, placebo-controlled, parallel-group, double-blinded, proof-of-concept study (RHO)
An immunometabolic signature of major depressive disorder in systemic lupus erythematosus
Treatment nonresponders in lupus nephritis characteristically exhibit persistent type I interferon signalling in monocytes: a longitudinal single-cell transcriptomic analysis
B cell depletion and BAFF receptor blockade with ianalumab (VAY736) for the treatment of moderate-to-severe systemic lupus erythematosus: a phase 2 randomised, double-blind, placebo-controlled trial with subsequent open-label treatment
1
Detection of abnormal movement in Parkinson's disease using time irreversibility and entropy
28
Study of the Relationships Between Gait Characteristics and Brain Function in Children With Cerebral Palsy During Walking
Comparing Physiological Cost Index Between the 2-Minute and 6-Minute Walk Tests Across Neurological Rehabilitation Cohorts
Early Prediction of Standing at Discharge in Moderate-to-Severe TBI: A Clinical Machine Learning Model Integrating Modifiable and Nonmodifiable Factors
A Randomized Trial to Evaluate the Efficacy of a Pain Neuroscience Education Program on Executive Function and Pain Intensity in Women With Fibromyalgia
Association Between a 1-Year Group-Based Telerehabilitation Program and the Quality of Life of People With Parkinson's Disease: An Observational Study
Trajectory of Mobility Function Decline for People With Motor Neuron Disease
Utilization and Cost of VA Outpatient Clinics for Service Members and Veterans Treated in VA Polytrauma Rehabilitation Centers for Traumatic Brain Injury: A VA TBI Model Systems Study
Characteristics of Dysphagia in Medullary and Cerebellar Stroke: An Observational Study Based on HRPM and FEES
Surgical Correction of Pes Equinovarus in People With Stroke: Effects on Personalized Goal Attainment and Balance and Gait Capacity
Impact of Right Cerebellar Theta Burst Stimulation on Post-Stroke Aphasia: A Randomized Controlled Trial
Gaps in Access to Cognitive Rehabilitation Referrals Among Veterans with Mild Traumatic Brain Injury
A Non-Inferiority Randomized Clinical Trial Comparing Three Delivery Formats of a Rehabilitation Intervention to Reduce Fatigue among People with Multiple Sclerosis
Activity Measure for Post-Acute Care, Computer Adapted Test versus “6-Clicks”; do they agree in individuals post-ischemic acute stroke?
A Novel Examination of the Impact of Time and Reliability on Minimal Detectable Differences Using the Coma Recovery Scale – Revised
Effects of a Hybrid Telerehabilitation Model on Mobility and Functional Capacity in patients with Multiple Sclerosis: A Single Blind Randomized Controlled Study
Differences in narrative discourse ability in traumatic brain injury and a neurotypical comparison group: Influence of age, education, and sex
Echoes of the Battlefield: Five-Year Longitudinal Cognitive Trajectories Show Trend of Recovery for Deployment-Related Mild TBI in the LIMBIC-CENC Cohort
New Diagnostic Criteria for Mild Traumatic Brain Injury: Medical-Legal Considerations
Associations between post-traumatic seizures, antiseizure medication, and duration of post-traumatic amnesia: a retrospective cohort analysis
Understanding multidimensional apathy in traumatic brain injury
Predicting Suicidality in Veterans/Service members over 5 Years after TBI: A VA Model Systems Study
Quality and outcomes of acute stroke care for people with and without aphasia
Primary Care and Brain Injury Physician Utilization for Persons Living with Chronic Brain Injury
A Three-Point Perspective on Post-Stroke Fatigue: A Grounded Theory Study
A Qualitative Examination of Chronic Care Needs of People with Traumatic Brain Injury
Dysphagia Screening in Acute Stroke: Adaptation and Validation of Modified Volume Viscosity Swallowing Test with International Dysphagia Diet Standardisation Initiative Standards
Development and Validation of a Prognostic Model for Independent Walking in Children with Cerebral Palsy Based on Machine Learning
Moderating Effects of Clinical and Social Factors on Fatigue Improvement after an Online Peer-led Fatigue Self-management Intervention in People with Systemic Sclerosis: A Secondary Analysis of a Randomized Controlled Trial
4
Efficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: the Randomized, Phase 3, TULIP‐SC Study
Visual hypersensitivity as a transdiagnostic marker of surgical pain response in arthritis and chronic pain syndromes
Pharmacodynamic Effects of Litifilimab in Lupus in the LILAC Phase II Study: Rapid and Sustained Reductions in Type I Interferon‐Associated Gene Expression and Cytokines
FGL‐1 Modulates Inter‐Organ Communication by Controlling T Cell Homeostasis during the Onset of Sjögren's Disease
1
Strong signature of right-handed circularly polarized photoionization close to the cyclotron line in the atmosphere of magnetic white dwarfs
104
Nav1.5 in the dorsal root ganglion plays a crucial role in mechanical hypersensitivity
Evidence of skull bone translocator protein overexpression linked to multiple sclerosis progression
Early glymphatic failure in AppNL-F knock-in mice is linked to parenchymal border macrophages loss
Loss of REST associated with Alzheimer's disease pathology is ameliorated by NAD+
Progression independent of relapse and MRI activity and treatment strategies in multiple sclerosis
The deep brain stimulation response network in Parkinson’s disease operates in the high beta band
Dimethyl fumarate as a promising therapeutic candidate for virus-associated myelopathy
Cerebral amyloid angiopathy and Alzheimer's and related pathologies across APOE genotypes
Clinical-biological Alzheimer’s disease stage concordance: insights from cohorts and autopsy data
Spatial propagation of movement-related basal ganglia activity predicts parkinsonian motor state
Medial temporal ageing-related tau astrogliopathy below 66 years is associated with neurodegeneration
Brainstem pathology in anti-IgLON5 disease: new insights into early events and tau progression
Enhanced mGluR1 function causes motor deficits and region-specific Purkinje cell dysfunction
Vaccines mimicking conformational epitopes on α-synuclein fibrils provide immunity to Parkinson’s disease
Elucidating the nociceptive role of CGRP in migraine headache
Neuronal titration of Snca via enhancer disruption mitigates disease onset in a Parkinson's disease mouse model
Multimodal multicentre investigation of diagnostic and prognostic markers in disorders of consciousness
Treatment evolution in spinal muscular atrophy: insights from the SMArtCARE registry
A cause and protective treatment for acute and progressive disability and grey matter atrophy
Somatic gene mutations in the motor cortex of patients with sporadic amyotrophic lateral sclerosis
Natural experiment on neuroinflammatory disease incidence and infection links pre- and post-COVID-19
Immune alterations in schizophrenia and the effects of a therapeutic antibody: a neuroimaging study
Region-specific variations in the cerebrovasculature underlie disease progression in Parkinson's disease
Post-mortem evidence of pathogenic angiogenesis and abnormal vascular function in early Alzheimer's disease
Distinct cutaneous α-synuclein signatures in body-first and brain-first Parkinson’s disease subtypes
PET-MRI biomarkers reveal efficacy of a novel NLRP3 inhibitor in Parkinson’s disease models
A next-generation HDAC6 inhibitor for amyotrophic lateral sclerosis and frontotemporal dementia
Imposter in the brain: aetiological, clinical and neuroimaging characteristics of Capgras syndrome
Engineered neural stem cell vesicles activating Wnt promote blood–brain barrier repair after cerebral haemorrhage
Enhanced adenoviral reactivity in Guillain-Barré syndrome after SARS-CoV-2 infection and vaccination
Reference proteins to improve Core 1 and Core 2 Alzheimer’s disease CSF and plasma biomarkers
Atrophy progression in frontotemporal lobar degeneration-TDP-C with primary progressive aphasia
Transcriptome of the human C2 dorsal root ganglia in C1-2 arthrodesis surgery: insight for neck pain
Inhibition of GluN2B-containing N-methyl-D-aspartate receptors by radiprodil
The presymptomatic and early manifestations of semantic dementia
Targeting lipid droplets in FUS-linked amyotrophic lateral sclerosis mitigates neuronal and astrocytic lipotoxicity
Cortical tau deposition promotes atrophy in connected white matter regions in Alzheimer’s disease
Cerebellar pathology contributes to neurodevelopmental deficits in spinal muscular atrophy
PU.1 restores microglial dysfunction caused by C9ORF72 repeat expansions in neural organoids
A human striatal-midbrain assembloid model of alpha-synuclein propagation
Right hemisphere language network plasticity in aphasia
Skin intraneural phosphorylated α-synuclein is a highly specific biomarker for early Parkinson’s disease
Genotype-specific interferon signatures in amyotrophic lateral sclerosis relate to disease severity
Quantitative susceptibility mapping reveals differences between subtypes of Lewy body dementia
Aberrant striatal firing mediates impulsive decision-making in a mouse model of Parkinson’s disease
Advanced oxidation protein products activated TRPA1 in a neuropathic multiple sclerosis model
Brain signatures of nociplastic pain: Fibromyalgia Index and descending modulation at population level
Tipping the balance: the PD1-axis as modulator in chronic inflammatory demyelinating polyneuropathy
Associations between epilepsy-related polygenic risk and brain morphology in childhood
Leveraging machine learning to predict Parkinson's disease using pre-symptomatic proteomics data
Molecular and clinical spectrum of epilepsy-dyskinesia syndromes: a cross-sectional study of 609 patients
Parkinson’s disease progression is shaped by longitudinal changes in cerebral compensation
Synergistic effect between cortical cerebral microinfarcts and brain atrophy on cognitive decline
iIn vivo/i self-assembled SOD1-siRNAs mitigate muscle atrophy and denervation in amyotrophic lateral sclerosis
Activation and sensitization of meningeal nociceptors by PACAP-38: implications for migraine headache
Phenotypic clustering in tuberous sclerosis complex reveals four distinct disease trajectories
Midbrain cytotoxic T cells as a distinct neuropathological feature of progressive supranuclear palsy
Proprioceptive synaptic dysfunction is a key feature in mice and humans with spinal muscular atrophy
Hippocampus and basal forebrain degeneration differentially impact cognition in Lewy body spectrum disorders
Structural network-specific effect of extreme capsule stimulation for drug-resistant focal epilepsy
Behavioural changes in frontotemporal dementia and their cognitive and neuroanatomical correlates
Traumatic brain injury or head impacts from contact sports are associated with tau astrogliopathy
Transcriptomic disruption and hypoactivity in DYT-SGCE medial ganglionic eminence-patterned inhibitory neurons
Intra-putaminal muscarinic receptor agonist infusion induces a dystonic phenotype in non-human primate
Neurodegenerative disease in iC9orf72/i repeat expansion carriers: population risk and effect of iUNC13A/i
Comparative effectiveness of anti-seizure medications in emulated trials using medical informatics
Occludin modulates HIV and ischaemic stroke response via mitochondrial antiviral signalling pathway
Brain atrophy patterns in anti-IgLON5 disease
The influence of the glymphatic system on α-synuclein propagation: the role of aquaporin-4
Brain regulation of pulmonary dysfunction induced by stroke
The association of seizure control with neuropathology in dementia
TIA1-mediated stress granules promote neurodegeneration by sequestering iHSP70/i mRNA in C9orf72 mice
Common neuropathologic change drivers of hippocampal sclerosis of ageing
Absence of the axon initial segment in sensory neuron enhances resistance to amyotrophic lateral sclerosis
Novel insight into TRPV1-induced mitochondrial dysfunction in neuropathic pain
Neuropathological comorbidity, genetics and cognition in a Chinese community-based autopsy cohort
Spreading depolarization triggers pro- and anti-inflammatory signalling: a potential link to headache
Artificial intelligence models using F-wave responses predict amyotrophic lateral sclerosis
Neuronal α-synuclein toxicity is the key driver of neurodegeneration in multiple system atrophy
Males but not females report genital sensations evoked by fixed-parameter stimulation of somatosensory cortex
Twins with temporal lobe epilepsy: genetic contributions to hippocampal sclerosis and other subtypes
Extreme exercise in males is linked to mTOR signalling and onset of amyotrophic lateral sclerosis
Amygdalar and hippocampal volume loss in limbic-predominant age-related TDP-43 encephalopathy
Cholinergic patterns correlate with dopamine medication ON freezing of gait in Parkinson’s disease
Stimulants for disorders of consciousness in the intensive care unit: a randomized, placebo-controlled trial
A digital motor score for sensitive detection of progression in Huntington’s disease
Charcot-Marie-Tooth disease type 1E: clinical natural history and molecular impact of iPMP22/i variants
Serotonergic dysfunction in patients with impulse control disorders in Parkinson’s disease
Redefining diagnostic lesional status in temporal lobe epilepsy with artificial intelligence
Post-mortem validation of in vivo TSPO PET as a microglial biomarker
Composite microRNA–genetic risk score model links to migraine and implicates its pathogenesis
Raised intracranial pressure alters cortical vascular function and cephalic allodynia
Plasma pTau181 and amyloid markers predict conversion to dementia in idiopathic REM sleep behaviour disorder
CSF proteomics of semorinemab Alzheimer’s disease trials identifies cell-type specific signatures
Anatomical progression of genetic frontotemporal lobar degeneration across the lifespan
Mapping the peripheral immune landscape of Parkinson’s disease patients with single-cell sequencing
Cholinergic basal forebrain degeneration in isolated REM sleep behaviour disorder
Pure autonomic failure: a natural history study of the Queen Square cohort
Neurotransmitter-informed connectivity maps and their application for outcome inference after stroke
Astrocytic mGluR5-dependent calcium hyperactivity promotes amyloid-β pathology and cognitive impairment
Linking polygenic risk scores to dopaminergic neuron loss using neuromelanin-sensitive imaging
Functional contribution of astrocytic Kir4.1 channels to spasticity after spinal cord injury
Oxygen extraction fraction in small vessel disease: relationship to disease burden and progression
Cholinergic degeneration in prodromal and early Parkinson’s: a link to present and future disease states
1
The NEON (Nerve rEpair Or Not) trial: a randomized controlled trial of microsurgical repair iversus/i nerve alignment for digital nerve injury
2
Sensory neurons drive pancreatic cancer progression through glutamatergic neuron-cancer pseudo-synapses
Long-range cholinergic input promotes glioblastoma progression
3
Spatial Cross-talk Modeling of the Tumor Microenvironment Identifies CCR5-Mediated Glia-to-Glia Signaling as a Key Regulator of Brain Metastatic Progression
C5aR1 inhibition alleviates cranial radiation-induced cognitive decline.
Alzheimer's Disease–Associated Amyloid-β Precursor Protein Prevents Aging Stress–Induced Mitophagy and Fumarate Depletion to Improve Antitumor Immunity
19
Efficient amyloid-β degradation in Alzheimer’s disease using SPYTACs
Meningeal blood vessel blockage enhances anti-glioblastoma immunity
Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder
Peripheral cancer attenuates amyloid pathology in Alzheimer’s disease via cystatin-c activation of TREM2
Myelin antigen capture in the CNS by B cells expressing EBV latent membrane protein 1 leads to demyelinating lesion formation
A glycolytic shunt via the pentose phosphate pathway is a metabolic checkpoint for nervous system sensory homeostasis and axonal regeneration
The effect of shingles vaccination at different stages of the dementia disease course
IL-1R1-positive dorsal raphe neurons drive self-imposed social withdrawal in sickness
Pathway-selective 5-HT1AR agonist as a rapid antidepressant strategy
Astrocytes functionally integrate multiple synapses via specialized leaflet domains
A brain center that controls consummatory responses
Microglia-astrocyte crosstalk regulates synapse remodeling via Wnt signaling
Molecular impact of antisense oligonucleotide therapy in C9orf72-associated ALS
Mast cells regulate the brain-dura interface and CSF dynamics
In vivo prime editing rescues alternating hemiplegia of childhood in mice
Cell-type-directed network-correcting combination therapy for Alzheimer’s disease
Deconstructing the intercellular interactome in vascular dementia with focal ischemia for therapeutic applications
The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis
The structure of human sweetness
1
Bioengineered gut bacterium synthesizing levodopa alleviates motor deficits in models of Parkinson’s disease
2
Galnt2 neurons in the ventromedial hypothalamus counterregulate hypoglycemia via a brain-liver neurocircuit
Endoplasmic reticulum Nogo drives AgRP neuronal activation and feeding behavior
4
Decoding the spatiotemporal development of the blood-brain barrier in human cortex
Transcriptional code for circuit integration in the injured brain by transplanted human neurons
Human stem cell-derived A10 dopaminergic neurons specifically integrate into mouse circuits and improve depression-like behaviors
An organ-chip model of sporadic ALS using iPSC-derived spinal cord motor neurons and an integrated blood-brain-like barrier
1
A triosmium carbonyl cluster that inhibits α-synuclein aggregation and disassembles preformed aggregates
5
Structural insights into copper and zinc binding to tau protein and the impact of metal binding on amyloid aggregation
Microfluidic-mass spectrometry analysis of blood–brain barrier transport using engineered microparticle interfaces
Amplification of magnetic field effects via critical dynamics in a nonlinear oscillatory system
Detecting alpha-synuclein aggregates with small molecules on single-molecule array
Combating multiple aetiologies of Alzheimer's disease to rescue behavioural deficits
1
Apolipoprotein D, a Novel Ligand for CD36, Is Essential for Blood-Brain Barrier Integrity.
5
Herpes Simplex Virus Type 1 Encephalitis: A Prospective Population-Based Cohort Study
Cerebral Malaria and Severe Malarial Anemia, but not Other Forms of Severe Malaria, Are Associated With Long-Term Cognitive Impairment
Changing Clinical and Laboratory Characteristics of Progressive Multifocal Leukoencephalopathy: A Retrospective National Cohort Study
Electroencephalogram Features Distinguish Cases of Cerebral Malaria Among Malawian Children With Fever and Coma
Non-Operative versus Neurosurgical Treatment of Brain Abscess: An Emulated Trial Nested within a Nationwide, Population-Based Cohort
7
Results of the Pediatric Guideline Adherence and Outcomes (PEGASUS) Program Versus Usual Care Pragmatic Randomized Controlled Trial in Severe Traumatic Brain Injury.
Sex Disparities in the Clinical Management and Outcomes of Critically Ill Adults Undergoing Electroencephalography Monitoring.
Explainable Machine Learning for Coma Outcome Prediction Based on Structural and Functional Brain MRI.
Unique Pattern of Coagulopathy Among Patients With Severe Traumatic Brain Injury: A Principal Component Analysis of Hemorrhagic Shock Trials.
Effect of Paracetamol on Cerebral Temperature in Febrile Brain-Injured Patients. The NEUROTHERM Study: A Randomized Controlled Pharmacodynamic Trial.
Early Relative Hypotension Below Noninvasive Cerebral Oximetry-Derived Optimal Blood Pressure Thresholds in Aneurysmal Subarachnoid Hemorrhage: A Pilot Study.
Added Value of Late Auditory Evoked Potentials in the Multimodal Prognostication of Patients With Disorders of Consciousness.
5
Hindbrain neurons that underlie water discrimination and consumption
Nocturnal ants navigate using a time-compensated lunar compass
Synaptic-like coupling of macrophages to myofibers regulates muscle repair
Functional organization of voice patches in marmosets and cross-species comparisons with macaques and humans
Distinct neural representations of hunger and thirst in neonatal mice before the emergence of food- and water-seeking behaviors
2
The p75 neurotrophin receptor controls the skeletal stem cell niche through sensory innervation
Early microglia progenitors colonize the embryonic CNS via integrin-mediated migration from the pial surface
1
Nonglycemic and Glycemic Risk Factors for Painful Neuropathic Symptoms and for Distal Symmetrical Polyneuropathy (DSPN) in the Diabetes Prevention Program/Diabetes Prevention Program Outcomes Study.
1
Increased S-adenosyl methionine strengthens the suppression in mitochondrial unfolded protein response induced by 6-PPD quinone at environmentally relevant concentrations in Caenorhabditis elegans
3
Exposure to low-dose ionizing radiation and dementia mortality in Canadian nuclear power plant workers
Transport of Bisphenol Analogues and Their Conjugated Metabolites Across Human Blood-Cerebrospinal Fluid Barrier
Beta-amyloid deposition increases in the brain with the progression of silicosis: a [18F] AV45 PET study in mice
1
Acrolein-Induced Alterations in Morphology and Stress Resilience in hiPSC-Derived Cortical Neurons
3
Dickkopf-related protein 2 impairs neurovascular Wnt signalling and worsens stroke outcome
Remote ischaemic conditioning improves outcomes of ischaemic stroke treated by endovascular thrombectomy: the SERIC-EVT trial
SCN10A-short gene therapy to restore conduction and protect against malignant cardiac arrhythmias
2
Single-nucleus multiomic profiling of the aging mouse substantia nigra reveals conserved gene alterations linked to Parkinson's disease
Transcriptional modulation unique to vulnerable motor neurons predicts ALS across species and SOD1 mutations
2
Kynurenic acid mitigates poststroke brain damage through the gut-brain neural circuit
Pathological tau propagation from the brain to the colon via the vagal efferent pathway in Alzheimer’s disease
12
Astrocytic calcium-dependent enzyme PAD2 governs microglia activity to exacerbate amyloid pathology via citrullinated vimentin
State-specific enhancer landscapes govern microglial plasticity
Remodeling of skull bone channels regulates immune infiltration into the meninges during neuroinflammation
Single-cell spatial transcriptomic profiling defines a pathogenic inflammatory niche in chronic active multiple sclerosis lesions
Notch3 destabilizes regulatory T cells to drive autoimmune neuroinflammation in multiple sclerosis
Rod-shaped microglia interact with neuronal dendrites to attenuate cortical excitability during TDP-43-related neurodegeneration
Sensory neurons shape local macrophage identity via TGF-β signaling
Cognate interaction-dependent pathogenicity of meningeal B cells drives neuroinflammation relapse
Excitatory-neuron-derived interleukin-34 supports cortical developmental microglia function
Optogenetic vagal nerve stimulation attenuates heart failure by limiting the generation f monocyte-derived inflammatory CCRL2+ macrophages
Inflammasome signaling in astrocytes modulates hippocampal plasticity
Interleukin-34-dependent perivascular macrophages promote vascular function in the brain
2
Current trends in stroke events, mortality, and case fatality in Switzerland: an epidemiologic update
Risk of stroke, myocardial infarction, coronary intervention, and atrial fibrillation or flutter in individuals experiencing typical migraine aura without headache: a Danish registry-based cohort study
3
Central amygdala neuropeptide Y neurons drive hedonic ingestive behaviour independent of energy homeostasis
Body mass index and the risk of ulnar nerve entrapment in individuals without diabetes—a longitudinal cohort study from Sweden
Long-term fasting-induced parasympathetic and sympathetic autonomic nervous system modulation in a subgroup of the GENESIS study
2
Intracranial Pressure Treatment Thresholds in Pediatric Traumatic Brain Injury
Prenatal Exposure to Zika Virus and Risk of Epilepsy-Related Hospitalization During Early Childhood
2
Multivariate Brain-Blood Signatures in Early-Stage Depression and Psychosis
Symptom Provocation and Clinical Response to Transcranial Magnetic Stimulation
10
Long-Term Cognitive Ability and Academic Achievement After Childhood Severe Malaria
Tenecteplase for Acute Non–Large Vessel Occlusion 4.5 to 24 Hours After Ischemic Stroke
Valacyclovir Treatment of Early Symptomatic Alzheimer Disease
Intra-Arterial Alteplase After Successful Endovascular Reperfusion in Acute Stroke
Levodopa Added to Stroke Rehabilitation
In Utero Embolization for Fetal Vein of Galen Malformation
Alteplase for Acute Ischemic Stroke at 4.5 to 24 Hours
Influenza-Associated Acute Necrotizing Encephalopathy in US Children
Intra-arterial Tenecteplase for Acute Stroke After Successful Endovascular Therapy
Frequency and Clinical Outcomes Associated With Tau Positron Emission Tomography Positivity
28
Oxidative stress impairs processive motility of the axonal transport motor KIF1A
Endothelin-1 induces Zfp36 family RNA-binding proteins and restrains cytokine and chemokine production in reactive astrocytes
Extracellular vesicles released from blood-brain barrier endothelial cells mediate brain Iron accumulation during LPS-induced brain Inflammation
Full-Length Tau Seeded by C-Shaped Tau Fibrils is Conformationally Variable
Multilineage differentiating stress-enduring cells alleviate neuropathic pain in mice through TGF-β and IL-10-dependent anti-inflammatory signaling
Downregulation of ClC-3 chloride channels in dorsal root ganglia neurons contributes to bone metastasis-induced pain
Conformation-specific monoclonal antibodies reveal early Tau structural intermediates in Alzheimer’s disease
Alzheimer’s disease-linked ACE variants increase ACE1 catalytic activity and production of angiotensin II
Structural and mechanistic characterization of heparin interactions with tau fibrils
O-GlcNAc Transferase Couples Nutrient Availability to Synaptic Plasticity in Paraventricular Neurons to Regulate Satiety
Skin-derived α-synuclein strains from PD, DLB, and MSA induce distinct intracellular pathology and neurodegeneration
Seeding biosensor cell line that reproduces the Alzheimer tau fold
An extra residue in the electron transfer chain holds the key for the dual functions of an animal-like cryptochrome
Up-regulation of miR-361-5p attenuates MPP+_induced neurotoxicity in dopaminergic SH-SY5Y cells as Parkinson's disease model
Development of a robust, physiologically relevant neuronal tau aggregation assay for tau-related drug discovery
Phosphatidylinositol 3-phosphate metabolism impacts cellular α-synuclein localization in Saccharomyces cerevisiae
In situ metabolomics reveals intra-islet metabolite changes upon in vivo stimulation of insulin secretion
The cation channel Trpa1 and chemokine Cxcl1 mediate axonal degeneration in spared nerve injury–induced neuropathic pain
Multifunctional molecular agent for tau-targeted combinational therapy of Alzheimer’s disease
Polyserine–tau interactions modulate tau fibrillization
Opt1 imports CoA precursors as glutathione mixed disulfides
Targeted degradation of α-synuclein by arginine-based PROTACs
USP10 inhibits the degradation of α-synuclein, a pathogenic factor associated with Parkinson's disease, by inhibiting chaperone-mediated autophagy
Targeting HIF-P4H-2 in APP/PS1 Alzheimer’s mouse model improves glucose metabolism, reduces dystrophic neuritis, and maintains exploratory activity
Microglial TAK1 promotes neurotoxic astrocytes and cognitive impairment in LPS-induced hippocampal neuroinflammation
Inactivation of SIAH-1 E3 ligase attenuates Aβ toxicity by suppressing ubiquitin-dependent DVE-1 degradation in Caenorhabditis elegans models of Alzheimer’s disease
A Novel Compound DBZ Alleviates Chronic Inflammatory Pain and Anxiety-Like Behaviors by Targeting the JAK2-STAT3 Signaling Pathway
Parkin mediates the mitochondrial dysfunction through mRpL18
4
MRI Assessment of Median Nerve Size in Patients with Proximate Electrodiagnostic Studies.
Subjective and Functional Dysphagia After Anterior Cervical Spine Surgery: A Prospective Controlled Study.
Spinal Fusion in Patients with GMFCS IV or V Cerebral Palsy: Durable Correction and Lasting Quality of Life Improvements: Five-Year Multicenter Outcomes.
The Utility of a Prediction Model Using Neurological Examination Findings for Diagnosing Degenerative Cervical Myelopathy.
5
Rsp5/NEDD4 and ESCRT regulate TDP-43 toxicity and turnover via an endolysosomal clearance mechanism
Homocysteine disrupts lysosomal function by V-ATPase inhibition
SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity
Nonmuscle myosin II regulates presynaptic actin and neuronal mechanobiology in Drosophila
Lysosomal TPC2 channels disrupt Ca2+ entry and dopaminergic function in models of LRRK2-Parkinson’s disease
3
Clinical characteristics and anti-ZSCAN1 antibody titer analysis in a nationwide survey of ROHHAD (-NET) syndrome
Case Series of 46 Patients With Nonketotic Hyperglycemia-associated Chorea: A Retrospective Follow-up Study
Association Between Free Triiodothyronine and Diabetic Peripheral Neuropathy in Euthyroid Patients With Type 2 Diabetes
33
Anti-nephrin antibodies are not enriched in patients with primary and post-transplant recurrent podocytopathies
MESH1-mediated coenzyme A degradation drives ferroptosis sensitivity and muscle pathology
Pathogenic variants in BORCS5 Cause a Spectrum of Neurodevelopmental and Neurodegenerative Disorders with Lysosomal Dysfunction
Dysregulation of astrocytic DNAJC6 contributes to sporadic Parkinson’s disease pathogenesis
Aging-dependent microglial heterogeneity worsens outcomes in models of traumatic brain injury
Conserved sleep disturbances in FOXP1 syndrome originate from developmental dysregulation of peptidergic signaling
Four subtypes of disease-causing missense mutations underlie pathogenic protein interactions in neurodegenerative VPS13A disease
SHMT2 deficiency disrupts transcriptional regulation through homocysteine-mediated suppression of histone lactylation in Huntington’s disease models
N-acetyl-l-leucine lowers α-synuclein levels and improves synaptic function in Parkinson’s disease models
Disruption of CSF-1 receptor-mediated metal ion homeostasis in the murine brain promotes neurodegenerative disease
Inflammasome adaptor ASC promotes sustained neuroinflammation and mild cognitive impairment in a closed-head injury model
Neuronal SEL1L-HRD1 ER-associated degradation is essential for motor function and survival in mice
Neutrophil-microglia interaction drives motor dysfunction in neuromyelitis optica model induced by subarachnoid AQP4-IgG
Base editing rescues seizures and sudden death in a SCN8A mutation-associated developmental epileptic encephalopathy model
Mouse model of atypical DAT deficiency syndrome uncovers dopamine dysfunction associated with parkinsonism and ADHD
Astrocyte-intrinsic signaling of chitinase-like protein CHI3L1 drives inflammation and amplifies demyelination in neuromyelitis optica
Spinal α2δ-1 induces GluA3 degradation to regulate assembly of calcium-permeable AMPA receptors and pain hypersensitivity
ANKRD55 is a key regulator of T cell inflammation in multiple sclerosis
3D cultured human medium spiny neurons functionally integrate and rescue motor deficits in Huntington’s disease mice
Biallelic variants in ARHGAP19 cause a progressive inherited motor-predominant neuropathy
Targeting specific kinase substrates rescues increased colitis severity induced by the Crohn’s disease–linked LRRK2-N2081D variant
Aggregation shifts amyloid-β peptides from synaptogenic to synaptotoxic
Cell and molecular profiles in peripheral nerves shift toward inflammatory phenotypes in diabetic peripheral neuropathy
The NaV1.5 auxiliary subunit FGF13 modulates channels by regulating membrane cholesterol independent of channel binding
Sensory neuron–expressed FGF13 controls nociceptive signaling in diabetic neuropathy models
Age-dependent brain responses to mechanical stress determine resilience in a chronic lymphatic drainage impairment model
Cingulate retinoic acid signaling regulates neuropathic pain and comorbid anxiodepression via extracellular matrix homeostasis
MuSK cysteine-rich domain antibodies are pathogenic in a mouse model of autoimmune myasthenia gravis
Mutant THAP11 causes cerebellar neurodegeneration and triggers TREM2-mediated microglial activation in mice
4E-BP1–dependent translation in microglia controls mechanical hypersensitivity in male and female mice
Hyperinsulinemia-induced upregulation of adipocyte TPH2 contributes to peripheral serotonin production, metabolic dysfunction, and obesity
AgRP neuron hyperactivity drives hyperglycemia in a mouse model of type 2 diabetes
The gut microbiome controls reactive astrocytosis during Aβ amyloidosis via propionate-mediated regulation of IL-17
4
Amyloidosis of bridging veins is a pathologic feature of Alzheimer’s disease
Dynamic alterations of dural and bone marrow B cells in an animal model of progressive multiple sclerosis
A pathological missense mutation in the deubiquitinase USP5 leads to insensitivity to pain
Oligodendrocyte-derived IL-33 regulates self-reactive CD8+ T cells in CNS autoimmunity
3
Cerebral Venous Thrombosis in Previously Healthy Patients with Cryptococcal Meningitis
Adrenal Corticosteroids and Increased Intracranial Pressure in Nonimmunocompromised Patients With Cryptococcal Meningitis
Cerebrospinal Fluid Immune Cell Alterations in Women With Neuropsychiatric Long COVID
64
Genetically encoded constitutive upregulation of β2 subunit containing neuronal nicotinic acetylcholine receptors is neuroprotective in female parkinsonian mice
Rab27b: A Modulator of Lysosomal Function and Alpha-Synuclein Clearance in Parkinson's Disease
Voluntary Dissociation of Motor Unit Activity in the Vastii Muscles
Timbre Encoding in the Inferior Colliculus
A Direct Auditory Subcortical Route to the Amygdala Associated with Fear in Humans
Aberrant Cerebellar-Recipient Thalamic Activity in Two Mouse Models with Prominent Tremor or Bradykinesia
Stable Mechanoreceptive Somatotopy in Chronic Low Back Pain: Is Cortical Map Reorganization a Myth?
Frequency-dependent Inhibition during Deep Brain Stimulation of Thalamic Ventral Intermediate Nuclei
Hemodynamic and Electrophysiological Progression of the Rose Bengal Photothrombotic Stroke Model in Mice
Longevity factor klotho and resistance to cognitive deficits in individuals with Parkinson’s disease and in an α-synuclein mouse model
Hierarchical afferent connectivity drives population-wide bursting dynamics in a computational model of human-derived excitatory neuronal networks
Alzheimer’s Pathology Enhances Excitatory Synaptic Input and Integration in VTA Dopamine Neurons
Bed nucleus of stria terminalis enkephalin neurons contribute to depletion-induced salt appetite
Divergent Roles of Nucleus Accumbens D1- and D2-MSNs in Regulating Hedonic Feeding
Motoneurons inhibitory synapses homeostatically respond to neuronal activity and modulate Amyotrophic Lateral Sclerosis pathogenesis
Single-Cell-Resolution Fate Mapping Reveals Embryonic Venous Origins of Fenestrated Hindbrain Choroid Plexus Vasculature
The Role of Disulfide Bonds in the GluN1 Subunit in the Early Trafficking and Functional Properties of GluN1/GluN2 and GluN1/GluN3 NMDA Receptors
Spinal processing of spatiotemporally diverse tactile stimuli: Computational insights into allodynia and spinal cord stimulation
Attenuated single neuron and network hyperexcitability following microRNA-134 inhibition in mice with drug-resistant temporal lobe epilepsy
In Vivo Screen of Parkinson’s Disease GWAS Risk Genes Identifies ARIH2 as a Novel Regulator of α-Synuclein Toxicity in Dopaminergic Neurons
Alzheimer’s Disease Pathologies Affect Dopaminergic Neural Mechanisms of Memory
In Vivo Expression of an SCA27A-Linked FGF14 Mutation Results in Haploinsufficiency and Impaired Firing of Cerebellar Purkinje Neurons
The increased activity of CaV3.2 channels contributes to nociceptors’ hyperexcitability and chronic neuropathic pain following spinal cord injury in mice
Quantifying state-dependent control properties of brain dynamics from perturbation responses
Caudal Granular Insular Cortex to Somatosensory Cortex I: A critical pathway for the transition of acute to chronic pain
Non-canonical Taste Transduction of Sugars Elicits Responses in a Dedicated Subset of Gustatory Afferent Neurons
HDAC6 Inhibition Reduces Seeded Tau and α-Synuclein Pathologies in Primary Neuron Cultures and Wild-type Mice
Contributions of Sound Localization Cues to Azimuth Tuning in the Auditory Midbrain
Toward Unified Biomarkers for Focal Epilepsy
Aperiodic activity reflects pathologic waveform shapes in focal epilepsy
Gene Expression-Based Lesion–Symptom Mapping: FOXP2 and Language Impairments after Stroke
Structural plasticity of peptidergic and nonpeptidergic C afferent terminals in the medullary dorsal horn during craniofacial inflammatory pain
Trigeminal motor nucleus regulates microstructure of feeding behavior without affecting total food intake
Neural responses underlying interaural time difference discrimination as a function of sensory reliability in the barn owl
Disrupted Calcium Dynamics in Reactive Astrocytes Occur with End Feet–Arteriole Decoupling in an Amyloid Mouse Model of Alzheimer's Disease
Common Mechanism Underlying Synaptic Dysfunction Caused by Preformed Fibril-Induced Accumulation of α-Synuclein or Tau in a Culture Propagation Model
PolyQ-Expansion of Ataxin-2 Disrupts Microtubule Stability and Impairs Axon Outgrowth
Tonic GABA and Glycine Inhibition Control Pain Hypersensitivity via Limiting α2δ-1– and mGluR5–Dependent NMDA Receptor Activity at Primary Afferent→Excitatory Neuron Synapses
Rebound Bursting Selectively Enables Fast Dynamics in Dopamine Midbrain Neurons Projecting to the Dorsolateral Striatum
Origins of the Auditory Brainstem Response in Mice Using Source Localization of Topographic Multichannel EEG
Q Neuron-Induced Hypothermia Promotes Functional Recovery and Suppresses Neuroinflammation After Brain Injury
Peripheral Gating of Nociception Investigated with a Decerebrate, Arterially Perfused Preparation of the Rat
Characterization of Auditory Responsive Neurons in the Mouse Superior Colliculus to White Noise and Frequency-Restricted Sounds
MiR-153 Prevents NRF2 Nuclear Translocation to Drive Hypoperfusion-Related Cognitive Deficits by Targeting KPNA5
Spatiotemporal Dynamics of Lateral Na+ Diffusion in Apical Dendrites of Mouse CA1 Pyramidal Neurons
Early Life Injury Alters Spinal Astrocyte Development
Presenilin Loss Impairs Synaptic Transmission and Causes Axonal Degeneration through Ryanodine Receptor Dysfunction, Independent of γ-Secretase Activity
Marmoset Anterior Cingulate Area 32 Neurons Exhibit Responses to Presented and Produced Calls during Naturalistic Vocal Communication
Network Dysfunction Precedes Neurodegeneration in a dox-Regulatable TDP-43 Mouse Model of ALS-FTD
Perisynaptic Astroglial Response to In Vivo Long-Term Potentiation and Concurrent Long-Term Depression in the Hippocampal Dentate Gyrus
IGFBP2–Ceramide Pathway Mediates Divergent Myelin Breakdown in the PNS and CNS Following Injury
Cell Type-Specific Alterations in Excitability and Inhibition of Upper Motor Neurons in AlsinKO Mice, a Model of Juvenile Onset ALS
Multivariate White Matter Microstructure Alterations in Older Adults with Coronary Artery Disease
Retinoid-X-Receptor as a Mediator of Poststroke Recovery by Reversing Age-Associated Phenotypes of Microglia/Hematogenous Macrophages
Pharmacological and genetic approaches to downregulate FIS1 mitigate neuropathic pain
A rapid anterior auditory processing stream through the insulo-parietal auditory field in the rat
Positron Emission Tomography (PET) Neuroimaging of the Pink1-/- Rat Parkinson Disease Model with the Norepinephrine Transporter (NET) Ligand [18F]NS12137
Projection of Cortical Beta Band Oscillations to a Motor Neuron Pool Across the Full Range of Recruitment
Salience Signaling and Stimulus Scaling of Ventral Tegmental Area Glutamate Neuron Subtypes
Microglia Support Both the Singular Form of LTP Expressed by the Lateral Perforant Path and Episodic Memory
ALS mutations shift the isoelectric point of the KIF5A C-terminal inducing protein aggregation and TDP-43 mislocalization
A Positive Allosteric Modulator of the SERCA Pump Rescues Hippocampal Neuronal Circuits Dysfunction and Cognitive Defects in a Mouse Model of Alzheimer's Disease
Transcranial Focused Ultrasound Modulates Feedforward and Feedback Cortico-Thalamo-Cortical Pathways by Selectively Activating Excitatory Neurons
Targeting lysine α-ketoglutarate reductase to treat pyridoxine-dependent epilepsy
41
Psychological stress catalyses free radical–mediated activation of coagulation in humans
A cascade model of dynamic cerebral autoregulation
TRIP8bnano peptide prevents cAMP binding to HCN2 channels alleviating pain-like behaviors in rats with neuropathic pain
Photobiomodulation restores blood–brain barrier integrity after hypoxia via endothelial von Willebrand factor modulation in a humanised tricellular transwell model
Machine‐learning classification of motor unit types in the adult mouse
Trafficking and potentiation of Nav1.7 and Nav1.8 channels are mediated by IQGAP1
α‐Synuclein oligomers slow down action potential firing and enhance dopamine release by increasing Cav2.2 currents in midbrain dopaminergic neurons
Neuronal loss of the pentose phosphate pathway in the living nervous system is causally linked to [NADPH] reduction and elevated oxidative stress
Ageing does not impair motor neuron adaptations: comparable motor unit responses to strength training in young and older adults
Lactate potentiates NMDA receptor currents via an intracellular redox mechanism targeting GluN2B subunits: implications for synaptic plasticity
Posterior parietal cortex oscillatory activity reflects persistent spatial memory impairments induced by early hippocampal amyloidosis in male mice
The sympathoregulatory region of the mouse rostral brainstem relies on both GABA and glycine to generate inhibitory currents
Vagal sensory neurones directly synapse onto parasympathetic motor (DMV) neurones
The pyrogenic mediator prostaglandin E2 elicits warmth seeking via EP3 receptor-expressing parabrachial neurons: a potential mechanism of chills
How breathing disrupts vision: hyperventilation‐induced hypocapnia impairs oculomotor responses in resting humans
Transport‐related effects on intrinsic and synaptic properties of human cortical neurons: A comparative study
First in‐human microelectrode recordings of vagus nerve activity in heart failure
Amyloid β alters vascular CaV1.2 channel spatiotemporal properties
Profiling muscle mass, function and molecular signalling in females aged 18–80 years and their associations with sex hormones
Chronic hypoxia impairs L-type Ca2+ channel-mediated myogenic vasoconstriction and cerebral autoregulation in newborn lambs
The role of acid-base balance in cerebrovascular and ventilatory responses to CO2 during 10 h normobaric hypoxia
Ionic conductances driving tonic firing in Purkinje neurons of larval zebrafish
Enhancement of hippocampal interneuron excitability by NMDA receptor positive allosteric modulation
Haemodynamic‐energetic mechanism of sudden cardiac death in severe aortic stenosis: A modelling study
Characterization of NTS‐to‐VTA projection neurons reveals higher‐order synaptic organization and distinct responsiveness to cholecystokinin
Diet‐induced obesity in mice increases carotid body chemosensitivity via the leptin‐TRPM7 pathway
Hypoxia‐inducible factor‐2 stabilization is not sufficient to induce erythropoietin production in deeper medullary fibroblasts
Contusive spinal cord injury causes Nav1.8 dysfunction to upregulate small sensory neuron excitability
Ageing‐induced weakness of mouse NMJs is associated with reduced active zone density, synaptic event kinetics and presynaptic calcium entry
Ventilatory and cerebrovascular responses to exercise in lowlander children acclimatizing to high‐altitude
Targeting necroptosis protects against astrocyte death and hippocampal sclerosis in experimental temporal lobe epilepsy
Non‐invasive assessment of integrated cardiorespiratory network dynamics after physiological stress in humans
Dual functions of SNAP25 in mouse taste buds
Selective enhancement of the interneuron network and gamma‐band power via GluN2C/GluN2D NMDA receptor potentiation
Neural determinants of the increase in muscle strength and force steadiness of the untrained limb following a 4 week unilateral training
Acute intermittent hypercapnic hypoxia augments left ventricular contractility
Central terminals of primary afferents coordinate the spontaneous activity of dorsal horn neurons
Seizure‐related death exhibits a circadian rhythm independent of seizure timing or sleep in a mouse model of Dravet syndrome
Potassium homeostasis during disease progression of Alzheimer's disease
The contribution of age and sex hormones to female neuromuscular function across the adult lifespan
A polygenetic rat model of divergent aerobic capacity reveals a liver–brain interaction impacting Alzheimer's disease‐like phenotypes
18
Femtosecond Soft X-ray Absorption Spectroscopy Identifies Metal-Centered S1 Excited State of Cyanocobalamin
Electric Double Layer Phenomena Near Surfaces Irreversibly Trigger Assembly of Tau Protein
A Fluorescence Microscopy Platform for Time-Resolved Studies of Spin-Correlated Radical Pairs in Biological Systems
PROTAC-Mediated Degradation of mHTT Aggregates Attenuates Neurotoxicity in Cellular and R6/2 Mouse Models of Huntington’s Disease
Computational Screening-Assisted Design of Bioinspired Artificial Metalloenzymes with Efficient Cascade Biocatalysis To Alleviate Cerebral Ischemia-Reperfusion Injury
Protein Electrostatics Tune the Singlet–Triplet Energy Gap in Natural and Engineered Phototropin Light-Oxygen-Voltage (LOV) Domains
Dopamine-Induced Tau Modification Prevents Pathological Phosphorylation and Generates a Distinct Fibril Polymorph
Chiral Spindle-like Nanorods Reprogram Neuroinflammation by Catalyzing α-Ketoglutarate Biosynthesis
Protein and Solvent Reorganization Drives Radical Pair Stability in Avian Cryptochrome 4a
Mapping the Role of Monomer Conformation in the Amyloid Formation of α-Synuclein Splice Variants
Design of Tau Aggregation Inhibitors Using Iterative Machine Learning and a Polymorph-Specific Brain-Seeded Fibril Amplification Assay
An Engineered Supramolecular Fluorescent Chemosensor for Multiscale Visualization of Glutamate Dynamics in Living Systems
α-Synuclein Drives SNARE-Dependent Tubular Remodeling of Vesicles
Spectroscopic Characterization of Radical Pair Photochemistry in Nonmigratory Avian Cryptochromes: Magnetic Field Effects in GgCry4a
C-Terminal Radical Oxidation Inhibits α-Synuclein Aggregation and Cytotoxicity via an Oxidative Oligomer-Disrupting Pathway
Small Protein Domains as Potential Spin Labels for In Vitro, Cellular, and Light-Induced Dipolar EPR Spectroscopy
Mechanism of Giant Magnetic Field Effect in a Red Fluorescent Protein
Spin Manipulation Engineering of Photodynamic Intermediates: Magnetic Amplification of Oxyradicals Generation for Enhanced Antitumor Phototherapeutic Efficacy
1
The Burden of Cardiovascular Disease in China Incidence Estimates From National Surveillance (2023)
7
Association Between Cholinesterase Inhibitor‐Overactive Bladder Antimuscarinic Prescribing Cascade and Risk of Delirium and Falls Among Individuals Living With Dementia
Clinician and Informant Report of Neuropsychiatric Symptoms in Dementia
Characterization of National Institute on Aging‐Funded Clinical Trials for Alzheimer's Disease
Utilization of Dysphagia Services Among Older Adults Hospitalized With Pneumonia in a Large Sample of scpUS/scp Hospitals
An Analysis of Institutional Anti‐Amyloid Websites
Exploring Antipsychotic Initiation Among Persons Living With Dementia in a Comprehensive Dementia Care Program
Readiness and Barriers to Participate in Alzheimer's and Dementia Research Among Older Adults
1
Risk models of cancer-related cognitive complaints among early breast cancer survivors in the CANTO cohort
2
Protection against ferroptosis through maintaining homeostasis of docosahexaenoate-containing phospholipids
α-Synuclein aggregates inhibit ESCRT-III through sequestration and collateral degradation
48
Blood-derived microRNA signatures associated with hippocampal structure and atrophy rate: findings from the Rhineland Study
IL-15 receptor alpha deficiency triggers depressive-like behaviors via enhanced microglial synapse pruning
Accelerated intermittent theta burst stimulation targeting personalized fronto-parietal control network improves core symptoms of autism spectrum disorder: a double-blind, randomized controlled trial
Anti-NMDAR encephalitis impairs intrinsic hippocampal dynamics through neuronal hypercoupling, hub dominance, and aberrant ensembles
Circuit-targeted modulation of anxiety symptoms in individuals with major depression: A randomized head-to-head TMS trial
Pallidal and subthalamic stimulations modulate inter-hemispheric interaction and asymmetry in Parkinson’s disease
The short-chain fatty acid butyrate prevents gut-brain amyloid-β pathology and neuroinflammation in an Alzheimer mouse model
Positive bias in brain and behaviour as a mechanism of transcranial magnetic stimulation depression treatment
Major depressive disorder shares systemic immune signatures and potential therapeutic targets with inflammatory skin diseases
The role of neural derived extracellular vesicles micro-ribonucleic acid cargo in white matter integrity in early-onset and late-onset bipolar disorder
Bidirectional association between immune-mediated diseases and major depressive disorder: evidence from cohort, genome-wide pleiotropic, and experimental studies
Tetrodotoxin-resistant NaV1.5 channels regulate excitability of lateral septum neurons and emotion behaviors of chronically stressed mice
The anti-NMDAR1 antibodies and IL-17 signaling pathway shape NMDAR encephalitis
A multi-ancestry meta genome-wide association study of migraine among veterans: associations with traumatic brain injury, depression, and post-traumatic stress disorder
In vivo-measured Lewy body pathology is associated with neuropsychiatric symptoms across the Alzheimer’s disease continuum
Dopaminergic tone inhibits spontaneous glutamate release and augments homeostatic synaptic plasticity
Meningeal macrophages alleviate social memory defects in an early Alzheimer’s disease model
Selective magnetic stimulation downregulates the GABA receptor ε subunit in the left prelimbic cortex to alleviate schizophrenia-like behaviors in mice
Alzheimer’s disease and memantine effects on NMDA-receptor blockade: non-invasive in vivo insights from magnetoencephalography
Cortical microstructure is associated with disease severity and clinical progression in genetic frontotemporal dementia: a GENFI study
Gesture deficits in psychosis and the combination of group psychotherapy and transcranial magnetic stimulation: A randomized clinical trial
Differential effect of cannabis use and antipsychotic medication on extracellular free-water in the brain of individuals with early psychosis and controls
Connectome-based markers predict the sub-types of frontotemporal dementia
Transcranial temporal interference stimulation for treating bipolar disorder with depressive episodes: a feasibility Study
Role of LXRβ in oligodendrocytes in neuronal survival
Reward circuit function and treatment outcome following vALIC deep brain stimulation in treatment-resistant depression
Forebrain-specific loss of erythropoietin provokes compensatory upregulation of different EPO receptors
Frontotemporal dementia patient-derived iPSC neurons show cell pathological hallmarks and evidence for synaptic dysfunction and DNA damage
The alpha7 nicotinic acetylcholine receptor mediates network dysfunction in a mouse model of local amyloid pathology
Mapping symptom-general and symptom-specific targets for transcranial magnetic stimulation in schizophrenia: an electric-field modeling meta-analysis
Thalamo-frontal functional connectivity patterns in Tourette Syndrome: Insights from combined intracranial DBS and EEG recordings
Elevated SGK1 increases Tau phosphorylation and microtubule instability in Alzheimer’s patient-derived cortical neurons
Astrocytic Mettl14 depletion enhances cognitive function by attenuating astrogliosis via the DUSP1/MAPK pathway in APP/PS1 mice: targeting neuroinflammation in Alzheimer’s disease
Estrogen receptor beta in lateral habenula mediates antidepressant effects of estrogen in postpartum-hormone-withdrawal-induced depression
Epigenetic, ribosomal, and immune dysregulation in paediatric acute-onset neuropsychiatric syndrome
Postmortem tissue biomarkers of menopausal transition
The NMDAR/TRPM4 death complex is a major promoter of disease progression in the 5xFAD mouse model of Alzheimer’s disease
Efficacy and safety of transcutaneous auricular vagus nerve stimulation for patients with treatment-resistant schizophrenia with predominantly negative symptoms: a randomized clinical trial and efficacy sensitivity biomarkers
Differential effects of lithium on metabolic dysfunctions in astrocytes derived from bipolar disorder patients
Predictive value of subgenual cingulate normative connectivity to TMS treatment site for antidepressant response in routine clinical practice: a prospective, multisite cohort study
Plasma neurofilament light reflects more severe manifestation of Alzheimer’s disease in men
Opposing roles of microglial and macrophagic C3ar1 signaling in stress-induced synaptic and behavioral changes
Comparative effects of 10-Hz rTMS and iTBS on cortico-striatal connectivity in major depressive disorder: a sham-controlled study
Integrated multi-omics analyses of synaptosomes revealed synapse-associated novel targets in Alzheimer’s disease
Cell autonomous microglia defects in a stem cell model of frontotemporal dementia tau
White matter disconnection in acquired criminality
Reduced glymphatic clearance in early psychosis
CLN5 deficiency impairs glucose uptake and uncovers PHGDH as a potential biomarker in Batten disease
3
Simultaneous Profiling and Quantification of Tau and Its Phosphorylated Isomers Using Engineered FraC Nanopores
Complement C1q-Targeted Microglial Membrane Camouflaged Nanolipid Carriers for Synaptic Protection in Alzheimer’s Disease: A Bioinspired Alectinib Delivery Strategy
DNA Nanostructures for Modular Growth Factor Delivery and Peripheral Nerve Repair
32
Astrocytes connect specific brain regions through plastic networks
Population-scale repeat expansions elucidate disease risk and brain atrophy
An enteric neuron ionotropic receptor regulates salt stress resistance
Deconstruction of a spino-brain–spinal cord circuit that drives chronic pain
Magnetic resonance control of spin-correlated radical pair dynamics in vivo
Long-term thrombus-free left atrial appendage occlusion via magnetofluids
Human hippocampal neurogenesis in adulthood, ageing and Alzheimer’s disease
Highly dynamic dural sinuses support meningeal immunity
Astrocytes enable amygdala neural representations supporting memory
Parkinson’s disease as a somato-cognitive action network disorder
Intestinal macrophages modulate synucleinopathy along the gut–brain axis
Convergent evolution of scavenger cell development at brain borders
Ageing promotes microglial accumulation of slow-degrading synaptic proteins
Quantum spin resonance in engineered proteins for multimodal sensing
Mitochondrial transfer from glia to neurons protects against peripheral neuropathy
A probabilistic histological atlas of the human brain for MRI segmentation
Synthetic α-synuclein fibrils replicate in mice causing MSA-like pathology
Lymphoid gene expression supports neuroprotective microglia function
A parabrachial hub for need-state control of enduring pain
Repeated head trauma causes neuron loss and inflammation in young athletes
Alzheimer’s risk allele causes aberrant lipid droplets in microglia
SLC45A4 is a pain gene encoding a neuronal polyamine transporter
Microglia–neuron crosstalk via Hex–GM2–MGL2 maintains brain homeostasis
Nanobody therapy rescues behavioural deficits of NMDA receptor hypofunction
How short peptides disassemble tau fibrils in Alzheimer’s disease
Structural and functional characterization of human sweet taste receptor
Increased CSF drainage by non-invasive manipulation of cervical lymphatics
Milli-spinner thrombectomy
Astrocyte morphogenesis requires self-recognition
The subfornical organ is a nucleus for gut-derived T cells that regulate behaviour
Closed-loop vagus nerve stimulation aids recovery from spinal cord injury
Heterogeneous pericoerulear neurons tune arousal and exploratory behaviours
1
Clearance of intracranial debris by ultrasound reduces inflammation and improves outcomes in hemorrhagic stroke models
4
Characterizing the metabolomes of microglia, astrocytes and neurons in ageing and Alzheimer’s brains
Riboflavin metabolism shapes FSP1-driven ferroptosis resistance
Glucosylceramide-induced ectosomes propagate pathogenic α-synuclein in Parkinson’s disease
Endoplasmic reticulum–mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis
5
Tau phosphorylation impedes functionality of protective tau envelopes
Interactions with tau’s microtubule-binding repeats modulate amyloid-β aggregation and toxicity
ALDH2-mediated GABA biosynthesis regulates hippocampal LTP and learning adaptability
Pharmacological inhibition of PSPH reduces serine levels and epileptic seizures
Small-molecule dissolution of stress granules by redox modulation benefits ALS models
208
HCN1 is a primary HCN Pacemaker Channel in Neurons
CK2 inhibition suppresses glial inflammation in models of neuroinflammation and neurodegeneration
Neurons of the human subthalamic nucleus engage with local delta frequency processes during action cancellation
Oxidative stress causes a reversible decrease of deubiquitylases activity in old vertebrate brains
Auricular vagus nerve stimulation drives analgesia via an auricle–brain axis in a mouse model of neuropathic pain
Efficacy and safety of albumin combined with endovascular therapy in the treatment of patients with acute ischemic stroke: a randomized clinical trial
Renal coenzyme A (CoA) production from VB5 fuels stem cell proliferation and tumor growth
A midbrain circuit for high-fat-food induced conditioned taste aversion
Perirhinal cortex gains control of hippocampal seizures via broad downstream circuits in male mouse models
Dysfunction of the episodic memory network in the Alzheimer’s disease cascade
Transport and inhibition mechanisms of human glycine transporter 2
Single-nucleus brain transcriptomics reveals microglia dysfunction in multiple system atrophy
Thyrotropin-releasing hormone neurons of different hypothalamic nuclei increase energy expenditure
Variants in the proteasome regulator PSMF1 cause a phenotypic spectrum from parkinsonism to perinatal lethality
Remodeling synaptic connections via engineered neuron-astrocyte interactions
Dysregulation of macrophage lipid metabolism underlies intracellular bacterial neuroinvasion
Signaling cascades shape functional subpopulations of cortical astrocytes in male wild-type mice and APP/PS1dE9 Alzheimer’s disease model
TOX3 in hypothalamic POMC-lineage cells regulates energy balance via the PTEN-AKT signaling axis
Blood flow patterns in mice are regulated by interpericyte tunneling nanotubes connecting functionally-opposite neuronal areas
Deep visual proteomics uncovers nociceptor diversity and pain targets
Exposome-wide patterns predict brain health in aging
ASO therapy rescues NOTCH2NLC GGC repeat expansion-induced genomic damage, 3D chromatin structural abnormalities, and senescence
Distinct modes of dopamine modulation on striatopallidal synaptic transmission
Descending inhibitory rostral ventromedial medulla neurons cause widespread antinociception and contribute to the pain-inhibits-pain phenomenon
TNF alpha unmasks enteric malate aspartate shuttle dysfunction bridging Parkinson disease and intestinal inflammation
Characterizing spatiotemporal white matter hyperintensity pathophysiology in vivo to disentangle vascular and neurodegenerative contributions
Human narcolepsy is linked to degeneration of both locus coeruleus and hypocretin neurons
Restoring early postnatal synaptic dysregulation rescues motor neuron degeneration in a mouse model of Spinal and Bulbar Muscular Atrophy
Suppression of pathological oscillations with transcranial focused ultrasound in Parkinson’s disease
Ribonuclease 4 Functions in Nociceptor-Mediated Nerve Homeostasis
DRP1 induces neuroinflammation via transcriptional regulation of NF-ĸB.
Dopamine and serotonin inversely modulate D2 medium spiny neurons to regulate cocaine reward
Elucidating genetic backgrounds of myasthenia gravis in Japanese by genome-wide association studies and multi-omics analyses of thymoma
Dual-stiffness nanoparticles for compartment-specific drug delivery in stroke
Transcranial focused ultrasound induces source localizable cortical activation in resting state humans when applied concurrently with transcranial electric stimulation
Alzheimer’s Aβ catalyzes Tau phase separation and aggregation via early nanocluster solubilization
Behavioral screening defines the molecular Parkinsonism-related subgroups in Drosophila
Cerebrospinal fluid NPTX1 and NPTXR predict neurodegeneration and clinical progression in Alzheimer’s disease
Multi-modal dissection of cell-type specific TDP-43 pathology in the motor cortex
Multimodal evidence for hippocampal engagement and modulation by functional connectivity-guided parietal TMS
Selective weakening of population-coupled synaptic activity in vivo in a mouse model of amyloid-beta pathology
NF-κB activation in astrocytes impairs wound healing after traumatic brain injury in male mice
Motor learning and dopamine-dependent striatal synaptic plasticity are controlled by astrocytic MEGF10
Rapid modulation of choice behavior by ultrasound on the human frontal eye fields
Sex-specific differences in mediobasal hypothalamus in response to nutritional states
A reversible allosteric inhibitor of GlyT2 for neuropathic pain without on-target side effects
Feeding decision-making by a single neuron via disparate neurotransmitters
Photoacoustic computed tomography monitors cerebrospinal fluid dynamics and glymphatic function
A 3D gut-brain-vascular platform for bidirectional crosstalk in gut-neuropathogenesis
An in vivo and in vitro spatiotemporal profile of human midbrain development
Gut microbiota-dependent 24-hydroxycholesterol metabolism contributes to capsaicin-induced amelioration of Alzheimer’s disease-like pathology in mice
MerTK-triggered TGFβ1 autocrine signal regulates microglial response to neurodegeneration
A spatiotemporal atlas of cerebrovascular development in zebrafish
Anti-TLR2 immunotherapy modulates neuron-to-oligodendrocyte propagation of α-synuclein in mouse and human models
A radiolabeled dendrimer non-invasively identifies and tracks innate immune cell activation in a mouse model of experimental autoimmune encephalomyelitis
Spinal cord stimulation therapy for gait impairment in Parkinson’s disease: a double-blinded, randomised feasibility trial with an open extension
Structural basis for selective inhibition of human GABA transporter GAT3
The glymphatic system clears amyloid beta and tau from brain to plasma in humans
TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism
Spatial heterogeneity and subtypes of functional connectivity development in youth
The E3 ligases Itch and WWP2 regulate autoimmune neuroinflammation by controlling T2 to T17 cell conversion via interleukin-4-STAT5 axis in mice
Identification of and NLRP3 inflammasome activation in Alzheimer’s disease retina
C1q-dependent clearance of alpha-synuclein allows macrophages to transiently limit enteric synucleinopathy in male mice
Glycerol 3-phosphate acyltransferase exacerbates α-synuclein-induced toxicity by increasing lipid peroxidation
Intranasal blood-brain barrier bypass enables sequential mitochondria-targeted bioengineered nanolamellar system for ischemic stroke therapy
Precise excision of expanded GGC repeats in NOTCH2NLC via CRISPR/Cas9 for treating neuronal intranuclear inclusion disease
Identification of a thermogenic target in the dorsal raphe nucleus for weight management in mice
Cross-species evidence for a developmental origin of adult hypersomnia with loss of synaptic adhesion molecules
Closed-loop wearable neurostimulation system with triboelectric sensing to alleviate hemifacial spasms
Tau condensation on DNA mediates microtubule attachment suggesting a mitotic role for centromere-localized tau
4R-tau seeding activity reveals molecular subtypes in progressive supranuclear palsy
SigmaR1 is an auxiliary translocon factor with lipid-binding activity that regulates protein and lipid droplet homeostasis
Application of kilohertz-frequency block to mitigate off-target motor effects of vagus nerve stimulation in swine
High-fat diet disrupts a septal control on feeding to promote obesity in male mice
mGluR4–NPDC1 complex mediates α-synuclein fibril-induced neurodegeneration
Reduced Ventral Tegmental Area GABA neuron output contributes to hyperactivity in the activity-based anorexia model in female mice
Targeted antisense oligonucleotide treatment rescues developmental alterations in spinal muscular atrophy organoids
The Ku80-p53-SIRT1 axis in DNA damage response contributes to sporadic and familial ALS and FTD
The gut vagal sensory pathway drives postprandial sleep via activation of PVH-projecting GABAergic neurons in the NTS
Egr1 is a sex-dependent regulator of neuronal chromatin, structural plasticity, and behaviour
Human cerebrospinal fluid net flow enhanced by respiration during the awake state
Identification of a reactive astrocyte subpopulation during HIV-associated pain pathogenesis in mouse models
Transferrin-phosphatidylserine liposomes target TDP-43 and neuroinflammation in male mice with neuropathic pain
C1q drives neural stem cell quiescence by regulating cell cycle and metabolism through BAI1
Seed amplification of MSA alpha-synuclein aggregates preserves the biological and structural properties of brain-derived aggregates
NMDA receptors coordinate brain vascular development via neuron-to-endothelial tip cell crosstalk in zebrafish
Prime editing of the β adrenoceptor in the brain restores physiological REM sleep in a mouse model of Alzheimer’s disease
Aberrant adenosine A2A receptor signaling in the choroid plexus drives CSF hypersecretion and ventriculomegaly in hydrocephalus
No causal links between estradiol and female’s brain and mental health using Mendelian randomization
Longitudinal proteomic profiling of cerebrospinal fluid in untreated multiple sclerosis defines evolving disease biology
Aberrant neural activity in the peritumoral cortex underlies the progression of tumor-associated seizures
ZFP612 controls neuropathic pain through epigenetic repression of within the silencer–promoter loop in primary sensory neurons of male mice
Structural pharmacology of SV2A reveals an allosteric modulation mechanism in the major facilitator superfamily
Epigenetic age acceleration, telomere length, and neurocognitive function in long-term survivors of childhood cancer
Distinct brain alterations and neurodegenerative processes in cognitive impairment associated with post-acute sequelae of COVID-19
Gut mucin fucosylation dictates the entry of botulinum toxin complexes
Evidence for divergent cortical organisation in Parkinson’s disease and Lewy Body Dementia
Perimenopausal state oestradiol to progesterone imbalance drives Alzheimer’s risk via ERRα dysregulation and energy dyshomeostasis
Sox9 regulation of hexokinase 1 controls neuroinflammatory astrocyte subtypes in a rat model of neuropathic pain
Tripotent Lgr5 stem cells in the posterior tongue generate lingual, taste, and salivary gland lineages
Personalized biomarkers of multiscale functional alterations in temporal lobe epilepsy
Migration of CD8 + TSCM cells into intestine via PPBP–CXCR2 axis increases host stress susceptibility by inhibiting gut microbiome-derived homovanillic acid
Structural basis of vilazodone dual binding mode to the serotonin transporter
Prefrontal–bed nucleus of the stria terminalis physiological and neuropsychological biomarkers predict therapeutic outcomes in depression
Suppression of Huntington’s Disease Somatic Instability by Transcriptional Repression and Direct CAG Repeat Binding
Optogenetics-integrated gut organ culture system connects enteric neurons dynamics and gut homeostasis
Age modulates the link between stress-related neural activity and mortality
DISC1 Protects Against Zika Virus Infection and Long-Term Neurological Damage Through AMPK-mTOR-Mediated Autophagy
Molecular profiling of brain endothelial cell to astrocyte endfoot communication in mouse and human
The Genetic Architecture of the Human Corpus Callosum and its Subregions
Astrocytes distress triggers brain pathology through induction of δ secretase in a murine model of Alzheimer’s disease
Intrinsically accelerated cellular degradation is amplified by TDP-43 loss in ALS-vulnerable motor neurons in a zebrafish model
Sex-specific associations of gene expression with Alzheimer’s disease neuropathology and ante-mortem cognitive performance
Distinct spatiotemporal patterns of white matter hyperintensity progression
Development of [F]ACI-19626 as a first-in-class brain PET tracer for imaging TDP-43 pathology
Status dystonicus is a distinct state characterized by pallidal beta-band activity
Thalamocortical hodology to personalize electrical stimulation for focal epilepsy
Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency
Capturing disease severity in LIS1-lissencephaly reveals proteostasis dysregulation in patient-derived forebrain organoids
Astrocytes modulate neuronal development by S100A6 signaling
Estrogen-related receptor gene expression associates with sex differences in cortical atrophy in isolated REM sleep behavior disorder
Fate mapping of peripherally-derived macrophages after traumatic brain injury in mice reveals a long-lasting population with a distinct transcriptomic signature
In vivo imaging of the barrier properties of the glia limitans during health and neuroinflammation
Platelet activation plays a pro-inflammatory role in myasthenia gravis
Synthetic chaperone based on Hsp90-Tau interaction inhibits Tau aggregation and rescues physiological Tau-Microtubule interaction
A wireless optogenetic stimulation system for long-term function evaluation of mice forelimb with sub-nerve resolution
A doubly stochastic renewal framework for partitioning spiking variability
Munc13-1 restoration mitigates presynaptic pathology in spinal muscular atrophy
Brain–cervical lymph node crosstalk contributes to brain injury induced by subarachnoid hemorrhage in mice
Spatially-restricted inflammation-induced senescent-like glia in multiple sclerosis and patient-derived organoids
Gustatory thalamic neurons mediate aversive behaviors
Aging in mice alters regionally enriched striatal astrocytes
Targeting prostaglandin E2 receptor 2 in Schwann cells inhibits inflammatory pain but not inflammation
Gut microbial production of imidazole propionate drives Parkinson’s pathologies
Hemispheric asymmetry of tau pathology is related to asymmetric amyloid deposition in Alzheimer’s Disease
Isotope-encoded spatial biology identifies plaque-age-dependent maturation and synaptic loss in an Alzheimer’s disease mouse model
CSF total tau as a proxy of synaptic degeneration
Distinct manifestations of excitatory-inhibitory imbalance associated with amyloid-β and tau in patients with Alzheimer’s disease
SeeThrough: a rationally designed skull clearing technique for in vivo brain imaging
Prefrontal cortex astrocytes modulate distinct neuronal populations to control anxiety-like behavior
Integrating artificial intelligence and optogenetics for Parkinson’s disease diagnosis and therapeutics in male mice
Apelin as a CNS-specific pathway for fenestrated capillary formation in the choroid plexus
Investigational eIF2B activator DNL343 modulates the integrated stress response in preclinical models of TDP-43 pathology and individuals with ALS in a randomized clinical trial
Astrocyte priming enhances microglial Aβ clearance and is compromised by APOE4
Design of Ig-like binders targeting α-synuclein fibril for mitigating its pathological activities
Regional heterogeneity of the blood-brain barrier
Anti-CV2/CRMP5 autoantibodies as drivers of sensory neuron excitability and pain in rats
14-3-3 binding maintains the Parkinson’s associated kinase LRRK2 in an inactive state
Two-step detection of Lewy body pathology via smell-function testing and CSF α-synuclein seed amplification
SERBP1-PCIF1 complex-controlled m6Am modification in glutamatergic neurons of the primary somatosensory cortex is required for neuropathic pain in mice
The CCL2-CCR2 axis drives neuromuscular denervation in amyotrophic lateral sclerosis
Sleep drive, not total sleep amount, increases seizure risk
Choroid plexus-mediated CSF secretion remains stable in aging rats via high and age-resistant metabolic activity
Accelerated brain ageing during the COVID-19 pandemic
Hamsters with long COVID present distinct transcriptomic profiles associated with neurodegenerative processes in brainstem
A human brain network linked to restoration of consciousness after deep brain stimulation
Early intervention with electrical stimulation reduces neural damage after stroke in non-human primates
Synaptic enrichment of pSer129 alpha-synuclein correlates with dopaminergic denervation in early-stage Parkinson’s disease
Somatostatin-expressing interneurons induce early NO-driven and late specific astrocyte-mediated vasodilation
AI-guided patient stratification improves outcomes and efficiency in the AMARANTH Alzheimer’s Disease clinical trial
Mechanically robust neuroprotective stent by sequential Mg ions release for ischemic stroke therapy
Targeting modulation of the choroid plexus blood-CSF barrier and CSF hypersecretion via lipid nanoparticle-mediated co-delivery of siRNA and resveratrol
Synaptic loss pattern is constrained by brain connectome and modulated by phosphorylated tau in Alzheimer’s disease
Chronic cerebral hypoperfusion induces venous dysfunction via EPAS1 regulation in mice
Pericyte pannexin1 controls cerebral capillary diameter and supports memory function
Intraoperative nerve-specific fluorescence visualization in head and neck surgery: a Phase 1 trial
HDL-bound S1P affects the subventricular niche and early neuropathological features of Alzheimer’s disease
Cell-specific mechanisms drive connectivity across the time course of Huntington’s disease
Variable and interactive effects of Sex, APOE ε4 and TREM2 on the deposition of tau in entorhinal and neocortical regions
Boundary complexity of cortical and subcortical areas predicts deep brain stimulation outcomes in Parkinson’s disease
Brain-wide input-output analysis of tuberal nucleus somatostatin neurons reveals hierarchical circuits for orchestrating feeding behavior
Memantine inhibits calcium-permeable AMPA receptors
Glial reactivity correlates with synaptic dysfunction across aging and Alzheimer’s disease
Microglial cyclooxygenase-1 modulates cerebral capillary basal tone in vivo in mice
Reduction of neuronal activity mediated by blood-vessel regression in the adult brain
In vitro morphological profiling of T cells predicts clinical response to natalizumab therapy in patients with multiple sclerosis
A multicenter longitudinal study of cholinergic subgroups in Parkinson disease
Flavoproteins as native and genetically encoded spin probes for ESR spectroscopy
FABP7 is increased in progressive multiple sclerosis and induces a pro-inflammatory phenotype in monocytes through a glycolytic switch
SEMA3B switches axon-axon to axon-glia interactions required for unmyelinated axon envelopment and integrity
Noncanonical short-latency auditory pathway directly activates deep cortical layers
AAV-based delivery of RNAi targeting ataxin-2 improves survival and pathology in TDP-43 mice
Cholinergic basal forebrain neurons regulate vascular dynamics and cerebrospinal fluid flux
TGFα controls checkpoints in CNS resident and infiltrating immune cells to promote resolution of inflammation
Monoclonal humanized monovalent antibody blocking therapy for anti-NMDA receptor encephalitis
Refining centromedian nucleus stimulation for generalized epilepsy with targeting and mechanistic insights from intraoperative electrophysiology
Mechanism of human α3β GlyR regulation by intracellular M3/M4 loop phosphorylation and 2,6-di-tert-butylphenol interaction
Intracellular accumulation of amyloid-ß is a marker of selective neuronal vulnerability in Alzheimer’s disease
Concept transfer of synaptic diversity from biological to artificial neural networks
Atlas of Proteomic signatures of brain structure and its links to brain disorders
Pharmacological and physiological activation of TGR5 in the NTS lowers food intake by enhancing leptin-STAT3 signaling
Convergent mapping of a tremor treatment network
Glioma-neuronal circuit remodeling induces regional immunosuppression
An integrative systems-biology approach defines mechanisms of Alzheimer’s disease neurodegeneration
Single-cell RNA-sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS
Targeting C1q prevents microglia-mediated synaptic removal in neuropathic pain
Gabapentinoids confer survival benefit in human glioblastoma
Energy state guides reward seeking via an extended amygdala to lateral hypothalamus pathway
Control of spatiotemporal activation of organ-specific fibers in the swine vagus nerve by intermittent interferential current stimulation
A minimally invasive thrombotic model to study stroke in awake mice
Development of a brain-penetrant G9a methylase inhibitor to target Alzheimer’s disease-associated proteopathology
Machine learning-based meta-analysis reveals gut microbiome alterations associated with Parkinson’s disease
Astrocytic GLUT1 deletion in adult mice enhances glucose metabolism and resilience to stroke
Oral PRI-002 treatment in patients with MCI or mild AD: a randomized, double-blind phase 1b trial
Structures of native SV2A reveal the binding mode for tetanus neurotoxin and anti-epileptic racetams
Nageotte nodules in human dorsal root ganglia reveal neurodegeneration in diabetic peripheral neuropathy
Leveraging neonatal Fc receptor (FcRn) to enhance antibody transport across the blood brain barrier
Synaptic vesicle-omics in mice captures signatures of aging and synucleinopathy
5
Somatic mosaicism in ALS and FTD identifies focal mutations associated with widespread degeneration
Large-scale exome analyses reveal new rare variant contributions in amyotrophic lateral sclerosis
Single-cell expression QTL analyses of the human cerebellum reveal vulnerability of oligodendrocytes in essential tremor
Genetic modifiers of somatic expansion and clinical phenotypes in Huntington’s disease highlight shared and tissue-specific effects
Base editing of trinucleotide repeats that cause Huntington’s disease and Friedreich’s ataxia reduces somatic repeat expansions in patient cells and in mice
1
Population attributable fractions of a wide range of peripheral diseases for the burden of dementia
5
A spatially coordinated keratinocyte–fibroblast circuit recruits MMP9⁺ myeloid cells to drive type I interferon-driven inflammation in photosensitive autoimmunity
A transcriptomic microglia taxonomy across mouse and human pathologies
Distinct origins and niches determine the cellular responsiveness of CNS macrophages after repopulation
Clonal CD8+ T cells populate the leptomeninges and coordinate with immune cells in human degenerative brain diseases
Spatial proteomics of Alzheimer’s disease-specific human microglial states
18
Microbiome signature of Parkinson’s disease in healthy and genetically at-risk individuals
An acetylated Tau-174 CSF biomarker discriminates between TDP-43 and tau pathology in patients with frontotemporal lobar degeneration
LRRK2-targeting antisense oligonucleotide in Parkinson’s disease: a phase 1 randomized controlled trial
The TREM2 agonistic antibody AL002 in early Alzheimer’s disease: a phase 2 randomized trial
A quantitative DOPA decarboxylase biomarker for diagnosis in Lewy body disorders
High-dose nusinersen for spinal muscular atrophy: a phase 3 randomized trial
BCMA-directed mRNA CAR T cell therapy for myasthenia gravis: a randomized, double-blind, placebo-controlled phase 2b trial
Oral splicing modulator branaplam in Huntington’s disease: a phase 2 randomized controlled trial
Vagus nerve-mediated neuroimmune modulation for rheumatoid arthritis: a pivotal randomized controlled trial
Intrathecal onasemnogene abeparvovec for treatment-experienced patients with spinal muscular atrophy: a phase 3b, open-label trial
Intrathecal onasemnogene abeparvovec in treatment-naive patients with spinal muscular atrophy: a phase 3, randomized controlled trial
Myelin injury precedes axonal injury and symptomatic onset in multiple sclerosis
Pridopidine in early-stage manifest Huntington’s disease: a phase 3 trial
AI-driven reclassification of multiple sclerosis progression
A plasma proteomics-based candidate biomarker panel predictive of amyotrophic lateral sclerosis
Disruption of the cerebrospinal fluid–plasma protein balance in cognitive impairment and aging
Shared and disease-specific pathways in frontotemporal dementia and Alzheimer’s and Parkinson’s diseases
Ubrogepant for the treatment of migraine prodromal symptoms: an exploratory analysis from the randomized phase 3 PRODROME trial
53
Laminar organization of cellular microcircuits modulating human interictal epileptiform discharges
Brain motion is driven by mechanical coupling with the abdomen
Early dopamine disruption in the entorhinal cortex of a knock-in model of Alzheimer’s disease
White matter pathways mediating dorsolateral prefrontal TMS therapy for depression
UBQLN2 links proteotoxicity with lipid metabolism in neurodegeneration
Adversarial AI reveals mechanisms and treatments for disorders of consciousness
Organization of neuropeptide systems in the human brain
Circuit response to neuromodulation characterized with simultaneous deep brain stimulation and precision neuroimaging in humans
Persistent interferon signaling causes sensory neuron plasticity and pain before and during arthritis
Magnetic resonance microscopy maps widespread effects of Alzheimer’s disease on brain structures and behavior in mice
Autoimmune neuroinflammation leads to neuronal death via MIF nuclease-mediated parthanatos
Base barrier cells provide compartmentalization of choroid plexus, brain and CSF
Diversity and immune dynamics of choroid plexus macrophages are shaped by distinct developmental origins
Investigating the methodological foundation of lesion network mapping
Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals
Axonal Eif5a hypusination controls local translation and mitigates defects in FUS-ALS
Phosphorylated tau exhibits antimicrobial activity capable of neutralizing herpes simplex virus 1 infectivity in human neurons
A fully iPS-cell-derived 3D model of the human blood–brain barrier for exploring neurovascular disease mechanisms and therapeutic interventions
Bright light exposure suppresses feeding and weight gain via a visual circuit linked to the lateral hypothalamus
Oxidized phosphatidylcholines deposition drives chronic neurodegeneration in a mouse model of progressive multiple sclerosis via IL-1β signaling
Increased neural excitability and glioma synaptic activity drives glioma proliferation in human cortex
Large-scale drug screening in iPSC-derived motor neurons from sporadic ALS patients identifies a potential combinatorial therapy
The Alzheimer’s therapeutic Lecanemab attenuates Aβ pathology by inducing an amyloid-clearing program in microglia
Astrocytic Sox9 overexpression in Alzheimer’s disease mouse models promotes Aβ plaque phagocytosis and preserves cognitive function
Distinct transcriptomic and epigenomic responses of mature oligodendrocytes during disease progression in a mouse model of multiple sclerosis
Estrogen modulates reward prediction errors and reinforcement learning
Subsecond dopamine fluctuations do not specify the vigor of ongoing actions
Microglia modulate Aβ-dependent astrocyte reactivity in Alzheimer’s disease
TDP-43-dependent mis-splicing of KCNQ2 triggers intrinsic neuronal hyperexcitability in ALS/FTD
A lateral hypothalamic neuronal population expressing leptin receptors counteracts anxiety to enable adaptive behavioral responses
Differential synaptic depression mediates the therapeutic effect of deep brain stimulation
C9orf72 hexanucleotide repeat expansions impair microglial response in ALS
Region-specific drivers of CSF mobility measured with MRI in humans
Astrocytic Ca2+ prevents synaptic depotentiation by limiting repetitive activity in dendrites during motor learning
Muscle-derived miR-126 regulates TDP-43 axonal local synthesis and NMJ integrity in ALS models
Hormonal milieu influences whole-brain structural dynamics across the menstrual cycle using dense sampling in multiple individuals
A bottom-up septal inhibitory circuit mediates anticipatory control of drinking
Impaired capillary–venous drainage contributes to gliosis and demyelination in mouse white matter during aging
Embryonic motor neuron programming factors reactivate immature gene expression and suppress ALS pathologies in postnatal motor neurons
Hypoxia ameliorates neurodegeneration and movement disorder in a mouse model of Parkinson’s disease
Tau PET positivity in individuals with and without cognitive impairment varies with age, amyloid-β status, genotype and sex
Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy
Response of spatially defined microglia states with distinct chromatin accessibility in a mouse model of Alzheimer’s disease
Closed-loop electrical stimulation prevents focal epilepsy progression and long-term memory impairment
Heat shock proteins function as signaling molecules to mediate neuron–glia communication in C. elegans during aging
Protective exercise responses in the dentate gyrus of Alzheimer’s disease mouse model revealed with single-nucleus RNA-sequencing
A route for cerebrospinal fluid flow through leptomeningeal arterial–venous overlaps enables macromolecule and fluid shunting
Noninvasive reduction of neural rigidity alters autistic behaviors in humans
Neuronal aging causes mislocalization of splicing proteins and unchecked cellular stress
Choroid plexus apocrine secretion shapes CSF proteome during mouse brain development
Lemborexant ameliorates tau-mediated sleep loss and neurodegeneration in males in a mouse model of tauopathy
GABA-dependent microglial elimination of inhibitory synapses underlies neuronal hyperexcitability in epilepsy
Microglia activation orchestrates CXCL10-mediated CD8+ T cell recruitment to promote aging-related white matter degeneration
3
Midkine attenuates amyloid-β fibril assembly and plaque formation
Structural analyses define the molecular basis of clusterin chaperone function
Distinct tau filament folds in human MAPT mutants P301L and P301Tc
44
Astrocyte cell volume dynamics across cortical states and transitions
Tau seeds induce neurofibrillary tangle formation across brain regions via individual-specific connectivity
Presynaptic P/Q calcium channel deficit promotes postsynaptic excitability remodeling and neurogenesis in developing thalamic circuitry
Deletion of SPI1 in microglia exacerbates amyloid pathology by impairing microglial response in Alzheimer’s disease models
Temporal regulation of human reactive astrocytes reveals their capacity for antigen presentation
Enhancers that direct gene expression to central nervous system vascular endothelial cells in vivo
Basolateral amygdala astrocytes encode anxiety states
Targeting PGAM5-driven mitochondrial integrated stress response slows ALS progression across subtypes
Astrocytic H3 receptors regulate anxiety through GABA signaling
Synthetic serum markers enable noninvasive monitoring of gene expression in primate brains
Stochastic misfolding drives the emergence of distinct α-synuclein strains
Astrocyte-microglia crosstalk through Hevin and Toll-like receptor signaling controls developmental thalamocortical synapse refinement
Developmental reprogramming in melanocortin neurons modulates diet-induced obesity in mice
A dorsal hippocampus-prodynorphinergic dorsolateral septum-to-lateral hypothalamus circuit mediates contextual gating of feeding
Hippocampal estrogen levels, receptor types, and epigenetics contribute to sex-specific memory vulnerabilities to concurrent acute stresses
Neurons undergo IFNγ-driven persistent epigenetic shifts and synaptopathy in encephalitis
The Alzheimer’s disease risk genes MS4A4A and MS4A6A cooperate to negatively regulate TREM2 and microglia states
TDP-43 dysfunction compromises UPF1-dependent mRNA metabolism in ALS
Biased histamine signaling selectively gates fat preference
C5aR1+ microglia exacerbate neuroinflammation and cerebral edema in acute brain injury
Hypertension-induced neurovascular and cognitive dysfunction at single-cell resolution
The brain neurovascular epigenome and its association with dementia
BST2 expression at astrocyte borders promotes microglial recruitment via the C3/C3aR signaling
The gain-of-function TREM2-T96K mutation increases risk for Alzheimer’s disease by impairing microglial function
Lcn2 from neutrophil extracellular traps induces astrogliosis and post-stroke emotional disorders
Regionally mapped astrocytic responses to cortical and white matter stroke show differential roles in astrocyte-induced vascular remodeling
Restoration of temporal separability between beta and movement ensemble co-firing with motor recovery
Segregated supramammillary-dentate gyrus circuits modulate cognitive and affective function in healthy and Alzheimer’s disease model mice
Astrocyte-mediated central amygdala microcircuit gates comorbid anxiety symptoms in chronic pain
Identification of a neural basis for energy expenditure in the mouse arcuate hypothalamus
Neural basis of transcutaneous electrical nerve stimulation for neuropathic pain relief
Microglia regulate neuronal activity via structural remodeling of astrocytes
Optimized deep brain stimulation for anterior cingulate cortex inhibition produces antidepressant-like effects in mice
Identification of the velum interpositum as a meningeal-CNS route for myeloid cell trafficking into the brain
G-protein-coupled receptor ADGRG1 drives a protective microglial state in Alzheimer's disease through MYC activation
In vivo 7 Tesla MRI of non-human primate intracortical microvascular architecture
Spatiotemporal transcriptomic maps of mouse intracerebral hemorrhage at single-cell resolution
GADD45G operates as a pathological sensor orchestrating reactive gliosis and neurodegeneration
Encoding the glucose identity by discrete hypothalamic neurons via the gut-brain axis
Major-depressive-disorder-associated dysregulation of ZBTB7A in orbitofrontal cortex promotes astrocyte-mediated stress susceptibility
The cell-surface shared proteome of astrocytes and neurons and the molecular foundations of their multicellular interactions
Distinct molecular patterns in R6/2 HD mouse brain: Insights from spatiotemporal transcriptomics
Specific targeting of brain endothelial cells using enhancer AAV vectors
Distinct systemic impacts of Aβ42 and Tau revealed by whole-organism snRNA-seq
1
Peripapillary hyperreflective ovoid mass-like structures before and after intracranial decompression: a longitudinal cohort study
15
Ischemic stroke triggers brain-wide synaptic remodeling within four hours
Five energy metabolism pathways show distinct regional distributions and lifespan trajectories in the human brain
RIN1 regulates developmental and pain-related plasticity in spinal synapses via NMDA receptor subunit trafficking
Large-scale seroepidemiology uncovers nephro-urological pathologies in people with tau autoimmunity
Sleep deprivation and sleep intensity exert distinct effects on cerebral vasomotion and brain pulsations driven by the respiratory and cardiac cycles
Oxytocin neurons drive melanocortin circuit maturation via vesicle release during a neonatal critical period
Environmental noise-induced changes to the IC-SNc circuit promotes motor deficits and neuronal vulnerability in a mouse model of Parkinson’s Disease
Zebrafish fast muscle contractions avoid the mammalian requirement for voltage-gated Na+ channels
Brain-age models with lower age prediction accuracy have higher sensitivity for disease detection
Combining gamma neuromodulation and robotic rehabilitation after a stroke restores parvalbumin interneuron dynamics and improves motor recovery in mice
Identification and characterization of tumor-associated astrocyte subpopulations and their interactions with the tumor microenvironment in experimental glioblastomas
Seizure evolution in a mouse model of West syndrome involves complex and time-dependent synapse remodeling, gliosis and alterations in lipid metabolism
The immune receptor SLAMF5 regulates myeloid-cell mediated neuroinflammation in multiple sclerosis.
Neuron-specific Agrin splicing by Nova RNA-binding proteins regulates conserved neuromuscular junction development in chordates
Mapping cerebral blood perfusion and its links to multi-scale brain organization across the human lifespan
4
A scaffold attachment factor PHM-2 regulates synaptic transmission through SLO-2 potassium channel in C. elegans
The Drosophila G protein-coupled receptor, GulpR, is essential for lipid mobilization in response to nutrient-limitation
A fly model of SCA36 reveals combinatorial neurotoxicity of hexanucleotide and dipeptide repeats
Two pairs of CACNA1I (CaV3.3) variants with opposite effects on channel function cause neurodevelopmental disorders of varying severity
7
Association between gabapentinoid treatment, concurrent use with opioid or benzodiazepine and the risk of drug poisoning: A self-controlled case series study
Associations between epileptic seizures in pregnancy and adverse pregnancy outcomes: A systematic review and meta-analysis
Associations between falls and other serious adverse events and antihypertensive medication in individuals with dementia: An observational cohort study
Re-evaluating malarial retinopathy to improve its diagnostic accuracy in paediatric cerebral malaria: A retrospective study
Deep brain stimulation surgical timing, outcomes, and prognostic factors in patients with Parkinson’s disease: A Chinese retrospective multicenter cohort study
Intra-arterial selective hypothermia for acute ischemic stroke neuroprotection: A multicenter pilot trial in China
Safety and tolerability of intravenous liposomal GM1 in patients with Parkinson disease: A single-center open-label clinical phase I trial (NEON trial)
2
Boundary-Driven Delayed-Feedback Control of Spatiotemporal Dynamics in Excitable Media
Interdependent Scaling Exponents in the Human Brain
101
Quantitative assessment of flow between cerebrospinal and interstitial fluid compartments in humans
Lactoperoxidase is a candidate for mediating neuromelanin formation in the human substantia nigra
Failure of early B cell tolerance and possible BCR signaling dysregulation underlie NF155-mediated autoimmune nodopathies
Trem2 exacerbates ischemic brain injury through Gpnmb in a photothrombotic stroke model
Tanycyte-derived lactate activates astrocytic HCAR1 to modulate glutamatergic signaling and POMC neuron excitability
Distinct laminar origins of sensory-evoked high-gamma and low-frequency ECoG signals revealed by optogenetics
Metabolic trajectories in developing human neocortical neurons
Cytotoxic T cell recognition of α-synuclein drives pathogenic immune responses in multiple system atrophy
Fatty acid regulation of feeding in Caenorhabditis elegans reveals the potential ancestral origin of a GLP-1-like multiagonist signaling system
DIRAS2 modulates MAPK pathway–mediated ferroptosis to regulate excitation/inhibition balance and seizure susceptibility
Immune cell profiling reveals expanded stem cell–like memory T cells in anti-GAD65-associated neurological syndromes
GFAP+ FOXF2+ ependymal cells promote blood–brain barrier repair via DLL4–NOTCH signaling after neural injury
Inorganic phosphate and the rapid mobilization of metabolic energy in neurons
Sleep alters neurovascular and hydrodynamic coupling in the human brain
ATP13A2 restrains macrophage NLRP3 inflammasome activation to repress neurodegeneration via modulating mitochondrial homeostasis
High-affinity, structure-validated and selective macrocyclic peptide tools for chemical biology studies of Huntingtin
ODC1 restricts meningeal B cell age-associated-like phenotype and function in multiple sclerosis: A human and experimental study
Reversibility and β-sheet formation are decoupled in tau condensate aging
Stretch and flow at the gliovascular interface: High-fidelity modeling of astrocyte endfeet
Macrophage–glia interactions regulate immune damage to enteric neurons during West Nile virus infection
Substance P in the lateral hypothalamic area regulates binge‐like eating behaviors in mice
SV2A PET reveals synaptic density loss in experimental autoimmune encephalomyelitis and in a pilot multiple sclerosis study
Phagocytes as plaque catalysts: Human macrophages generate seeding-competent Aβ42 fibrils with cross-seeding activity
Huntington’s disease LIG1 modifier variant increases ligase fidelity and suppresses somatic CAG repeat expansion
A hybrid compass mechanism combining radical pairs and magnetite crystals
RNA-binding activity of PHGDH drives amyloid-beta production in a human brain organoid model of sporadic Alzheimer’s disease
Natalizumab exacerbates astrocytopathy in NMOSD via blockade of endothelial VCAM1–astrocytic integrin α4 interaction
Gustatory avoidance of fatty acids by Aedes aegypti depends on an arthropod-specific TRP channel
GABA corelease guides the functional maturation of glycinergic synapses in an auditory sound localization circuit
Olfactory inputs to appetite neurons in the hypothalamus
Microvascular architecture and physiological fluctuations constrain the control of cerebral microcirculation
Highly sensitive chemiluminescence imaging of misfolded proteins in neurodegenerative models
Hyperglycemia promotes SIRT3-mediated deacetylation of SARM1 to exacerbate diabetic peripheral neuropathy in mice
Prevention of ubiquitination at K6 and K9 in mutant huntingtin exacerbates disease pathology in a knock-in mouse model
USP25 inhibition ameliorates Parkinson’s disease by restoring mitophagy
Combination antiviral and anti-inflammatory therapy mitigates persistent neurological deficits in mice post SARS-CoV-2 infection
Long-term effects of forty-hertz auditory stimulation as a treatment of Alzheimer’s disease: Insights from an aged monkey model study
Peripheral nerve injury reduces macrophage efferocytosis to facilitate neuropathic pain
Competition between glycine and GABAA receptors for gephyrin controls their equilibrium populations at inhibitory synapses
PIP2 corrects an endothelial Piezo1 channelopathy
Preservation of anticorrelated brain networks predicts recovery after traumatic brain injury
Synaptic integration and competition in the substantia nigra pars reticulata—An experimental and in silico analysis
Structural insights into human signal peptide peptidase
Hormonal mechanisms of women’s risk in the face of traumatic stress
MBNL loss of function in smooth muscle as a model for myotonic dystrophy associated gastrointestinal dysmotility
Mapping epileptogenic brain using a unified spatial–temporal–spectral source imaging framework
Galectin-related protein, a key contributor, drives diabetes-associated neuropathic pain
Neuromodulatory control of energy reserves in dopaminergic neurons
Neurofluid circulation changes during a focused attention style of mindfulness meditation
Erasable serum markers
Mechanisms of transport and analgesic compounds recognition by glycine transporter 2
Dysregulated proteostasis in p.A53T-α-Synuclein astrocytes aggravates Lewy-like neuropathology in a Parkinson’s disease iPSC model
Predicted molecules followed by experimental validation for protecting human neurons from oxidative stress–induced cytotoxicity
Analgesia through FKBP51 inhibition at disease onset confers lasting relief from sensory and emotional chronic pain symptoms
Characterization of endothelin-converting enzyme 1 as a key enzyme in the multienzyme Aβ degradation pathway
Therapeutic IgG- and IgM-specific proteases disarm the acetylcholine receptor autoantibodies that drive myasthenia gravis pathology
Full interhemispheric integration sustained by a fraction of posterior callosal fibers
Parkinsonism disrupts the balance between excitatory and inhibitory activity within the primary motor cortex during movement
Dynamic control of NMDA receptor Ca2+ permeability by endogenous and synthetic modulators
Spontaneous activity of astrocytes is a stochastic functional signal for memory consolidation
Activity-dependent citrate dynamics in neurons
Geometrical compartmentalization of trigger waves
Higher-order interactions in neuronal function: From genes to ionic currents in biophysical models
Nav1.8: Intrinsic limits on the functional effect of abrogation in DRG neurons
Biomarkers of immune dysregulation and posttreatment inflammation in spinal muscular atrophy
Endothelial αvβ3 integrin induction during hypoxia protects blood–brain barrier integrity
Excitatory glycine receptors control ventral hippocampus synaptic plasticity and anxiety-related behaviors
Microglia contribute to bipolar depression through Serinc2-dependent phospholipid synthesis
Mechanisms underlying allosteric modulation of antiseizure medication binding to synaptic vesicle protein 2A (SV2A)
Amyloid β–dependent neuronal silencing through synaptic decoupling
Unraveling the neuroimmune mechanisms in cancer-induced bone pain: New horizons for therapeutic intervention of the two-phase paradigm
Dural ectopic lymphatic structures accumulate during aging and exhibit dysregulation in neurodegenerative diseases
Immune-responsive gene 1: The mitochondrial key to Th17 cell pathogenicity in CNS autoimmunity
Actions of the antiseizure drug carbamazepine in the thalamic reticular nucleus: Potential mechanism of aggravating absence seizures
Targeting PBK with small-molecule 1-O-acetyl-4R,6S-britannilactone for the treatment of neuroinflammation
Glycogen supports glycolytic plasticity in neurons
Thalamic CGRP neurons define a spinothalamic pathway for affective pain
Regulation of Na/Ca exchange by cytoplasmic protons modifies intracellular calcium dynamics and the cardiac response to ischemia
Vamp3/syntaxin 4 mediates the basolateral membrane fusion of TfR transcytosis across the BBB and is exploited by pathogenic Escherichia coli
Molecular basis for substrate recognition and transport of mammalian taurine transporters
Cerebral blood flow is modulated by astrocytic cAMP elevation independently of IP3R2-mediated Ca2+ signaling in mice
Multiomics integration prioritizes potential drug targets for multiple sclerosis
Fluid dynamics model of the cerebral ventricular system
S-adenosylmethionine metabolism buffering is regulated by a decrease in glycine N-methyltransferase via the nuclear ubiquitin–proteasome system
Decreased mitochondrial activity in the demyelinating cerebellum of progressive multiple sclerosis and chronic EAE contributes to Purkinje cell loss
Intermediate light adaptation induces oscillatory phototaxis switching and pattern formation in Chlamydomonas
Keratinocyte–TRPV1 sensory neuron interactions in a genetically controllable mouse model of chronic neuropathic itch
The analgesic paracetamol metabolite AM404 acts peripherally to directly inhibit sodium channels
Modulation of human dorsal root ganglion neuron firing by the Nav1.8 inhibitor suzetrigine
Neuron–astrocyte associative memory
Inhibiting 15-PGDH blocks blood–brain barrier deterioration and protects mice from Alzheimer’s disease and traumatic brain injury
Stathmin-2 enhances motor axon regeneration after injury independent of its binding to tubulin
Inflammatory cytokine upd3 induces axon length–dependent synapse removal by glia
Imaging a concussion and the ensuing immune response at the blood–brain barrier
Loss of insulin signaling in microglia impairs cellular uptake of Aβ and neuroinflammatory response exacerbating AD-like neuropathology
Myelin sheaths can act as compact temporary oxygen storage units as modeled by an electrical RC circuit model
Sex-chromosome complement and Activin-A shape the therapeutic potential of TNFR2 activation in a model of MS and CNP
Cardiac signals inform auditory regularity processing in the absence of consciousness
Spreading depolarizations exhaust neuronal ATP in a model of cerebral ischemia
Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy and specialized SNARE complex
Cortical signatures linked to behavior quantitatively track arousal levels
19
Endovascular versus Medical Management of Basilar Artery Occlusion Strokes in Patients with Low Stroke Severity.
Brain MRI Analysis of Cumulative Blast Exposure and Intracranial Aneurysms in Special Operations Forces.
Dynamic MRI of Fluid and Solute Transportation across the Arachnoid Barrier in the Human Meninges.
Simultaneous Brain Iron and α-Synuclein Detection in Patients with Synucleinopathies via Quantitative Susceptibility Mapping MRI.
Comparing Glymphatic Function Measures: Diffusion Tensor Image Analysis Along Perivascular Spaces (DTI-ALPS) versus Intrathecal Contrast-Enhanced MRI.
Evaluation of Tibial Nerve Microcirculation in Diabetes Mellitus at Superresolution US.
Endovascular Therapy versus Medical Management for Basilar Artery Occlusion Presenting beyond 24 Hours.
Endovascular Recanalization versus Medical Treatment Alone for Symptomatic Nonacute Intracranial Artery Occlusion: A Multicenter Cohort Study.
Statins Reduce Wall Enhancement at Vessel Wall MRI in Unruptured Vertebrobasilar Dissecting Aneurysms: A Randomized Controlled Trial.
Therapeutic Efficacy of Endovascular Thrombectomy in Acute Basilar Artery Occlusion with Mild Symptoms.
Endovascular Thrombectomy versus Standard Medical Management in Treatment of Acute Medium Vessel Occlusion Strokes: A Multicenter Registry.
Net Water Uptake at CT Predicts the Treatment Effect of Thrombectomy for Low ASPECTS Stroke.
Quantification of Perivascular Flow Dynamics of Human Cerebrospinal Fluid Along Major Arteries Using Phase-Contrast MRI.
Microstructural Bias in the Assessment of Periventricular Flow as Revealed in Postmortem Brains.
Susceptibility MRI Helps Predict Mild Cognitive Impairment Onset and Cognitive Decline in Cognitively Unimpaired Older Adults.
Quantitative Ultrashort Echo Time MRI for Evaluation of Sciatic Nerve Degeneration and Regeneration in Rat Models.
Stent-Assisted Angioplasty in Symptomatic Intracranial Stenosis without Adjacent Branch Atheromatous Disease: A Randomized Trial with Patients Selected by Using Three-Dimensional Rotational Angiography.
Diagnostic Value of Swallow Tail Sign at Brain MRI in Patients with Clinically Uncertain Parkinsonian Syndrome.
Association of Deep Learning-based Chest CT-derived Respiratory Parameters with Disease Progression in Amyotrophic Lateral Sclerosis.
11
Luminal surface proteome of the brain vasculature uncovers blood-brain barrier regulators
Blocking RAN translation without altering repeat RNAs rescues C9ORF72-related ALS and FTD phenotypes
A global screen for magnetically induced neuronal activity in the pigeon brain
Targeting formyl peptide receptor 1 reduces brain inflammation and neurodegeneration
Dysfunction in primate dorsolateral prefrontal area 46 affects motivation and anxiety
Discrete spatiotemporal encoding of striatal dopamine transmission
Microglia replacement halts the progression of microgliopathy in mice and humans
GPR45 modulates Gαs at primary cilia of the paraventricular hypothalamus to control food intake
Norepinephrine changes behavioral state through astroglial purinergic signaling
Norepinephrine signals through astrocytes to modulate synapses
GPCR signaling gates astrocyte responsiveness to neurotransmitters and control of neuronal activity
75
Directional guidance to orient Schwann cell alignment in nerve regeneration requires Plexin-B1
Broad presence of ferromagnetism in bees and relationship to phylogeny, natural history, and sociality
Regulation of autism-related self-injurious behavior by electrical stimulation of corticostriatal circuits in mice and humans
Vasculogenic tissue nanotransfection accelerates functional recovery after peripheral nerve injury
Selective vulnerability of cerebral vasculature to NOTCH3 variants in small vessel disease and rescue by phosphodiesterase-5 inhibitor
Self-inactivating AAV-CRISPR at different ages enables sustained amelioration of Huntington’s disease deficits in BAC226Q mice
Neurons with granulovacuolar degeneration bodies are resilient to tau-induced protein synthesis impairment
Inflamed vessel–anchored release of H2 across the blood-brain barrier for ischemic stroke neuroprotection
Enteric botulinum neurotoxins facilitate infection by Salmonella and Shigella
Tubulin polymerization dynamics are influenced by magnetic isotope effects consistent with the radical pair mechanism
Structural basis for domain coupling in heteromeric glycine receptors revealed by an atypical allosteric agonist
VMAT2 dysfunction impairs vesicular dopamine uptake, driving its oxidation and α-synuclein pathology in DJ-1–linked Parkinson’s neurons
Expansive spatial pattern of Aβ deposition in patients with cerebral amyloid angiopathy: A three-dimensional surface-to-depth analysis
In situ coagulation environment regulation–assisted thrombus clearance via hydrogenated silicon-based nanothrombolytics
α-Synuclein expression is required for somatodendritic dopamine release and immediate early gene induction
Neuroimmune activation in temporal lobe epilepsy patients with worsening seizure following the COVID-19 pandemic: A [18F]DPA-714 PET/MR study
Neuronal GPR75 deficiency protects against diet-induced obesity in a humanized mouse model
Cryo-EM of autoantibody-bound NMDA receptors reveals antigenic hotspots in an active immunization model of anti-NMDAR encephalitis
GluN2B-specific NMDAR positive allosteric modulation reverses cognitive and behavioral abnormalities in Mecp2 and Disc1 transgenic mice
BCMA/CD19 CAR T cell therapy for refractory myasthenia gravis: Proteomic signatures and single-cell transcriptomics of disease flares
GPNMB is a biomarker for lysosomal dysfunction and is secreted via LRRK2-modulated lysosomal exocytosis
Neurexin regulates mechanical nociceptive sensitization by central inhibition in Drosophila
Brainstem circuit for sickness-induced sleep
Down-regulation of gastrin-releasing peptide in medial orbitofrontal cortex to nucleus accumbens projections contributes to allodynia and negative affect
Multidimensional dynamic optical imaging unveils anesthetic-driven hemispheric lateralization in blood-brain barrier homeostasis
State-dependent modulation of spiny projection neurons controls levodopa-induced dyskinesia in a mouse model of Parkinson’s disease
CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology
Identification and characterization of botulinum neurotoxin–like two-component toxins in Paeniclostridium ghonii
Adhesive nonfibrotic bioelectronic interfaces on diverse peripheral nerves for long-term functional neuromodulation
Dopamine and serotonin cotransmission filters striatonigral synaptic activity via 5-HT1B receptor activation
Calcium-based synaptic and structural plasticity link pathological activity to synaptic reorganization in Parkinson’s disease
DKK3-LRP1 complex and a chemical inhibitor regulate Aβ clearance in models of Alzheimer’s disease
Preventing neuropathy and improving anticancer chemotherapy with a carbazole-based compound
Vasa vasorum plexus formation in intracranial aneurysm associates with microcalcification and wall thickening
The chloride intracellular channel 1 (CLIC1) is essential for microglial morphodynamics and neuroinflammation
Cryo-EM snapshots of NMDA receptor activation illuminate sequential rearrangements
Structure of the Huntingtin F-actin complex reveals its role in cytoskeleton organization
Chaperone nanomotors with chemotactic ability for the treatment of Parkinson’s disease
Differential modulation of movement speed with state-dependent deep brain stimulation in Parkinson’s disease
Brain stimulation preferentially influences long-range projections
Cytoskeletal control in adult microglia is essential to restore neurodevelopmental synaptic and cognitive deficits
Excitotoxic neuronal death requires superoxide entry into neurons through volume-regulated anion channels
Voice identity invariance by anterior temporal lobe neurons
A nut-and-bolt assembly of the bimodular large progenitor botulinum neurotoxin complex
Structure of the complete 14-subunit botulinum neurotoxin B complex reveals a unique anchoring through the narrow central pore of HA70
Cholinergic regulation of osteocyte mechanobiology: A paradigm for bone adaptation
N,N-dimethyltryptamine mitigates experimental stroke by stabilizing the blood-brain barrier and reducing neuroinflammation
Precise rewiring of corticospinal axons and spinal interneurons via near-infrared optogenetics for spinal cord injury treatment
Neuronal Reg3β/macrophage TNF-α–mediated positive feedback signaling contributes to pain chronicity in a rat model of CRPS-I
Delivery of a fibrin-binding hemostatic polymer ameliorates neurovascular damage and neural tissue loss after traumatic brain injury
G proteins of the G12 family expressed by POMC neurons regulate key metabolic functions
Synthetic efferocytic receptor microglia enhances anti-inflammatory clearance of amyloid-β for AD treatment in mice
SARS-CoV-2 induces Alzheimer’s disease–related amyloid-β pathology in ex vivo human retinal explants and retinal organoids
Perineural immune environment of olfactory nerves is reshaped by neuroinflammatory drainage and connects to ethmoid bone marrow
Dorsal raphe nucleus controls motivation-state transitions in monkeys
Opposite regulation of medullary pain–related projection neuron excitability in acute and chronic pain
Differential pathological dynamics triggered by distinct Parkinson patient–derived α-synuclein extracts in nonhuman primates
Reduced DJ-1-F1Fo ATP synthase association correlates with midbrain dopaminergic neuron vulnerability in idiopathic Parkinson’s disease
Inhibition of acute lung inflammation by a neuroimmune circuit induced by vagal nerve stimulation
Type II kinase inhibitors that target Parkinson’s disease–associated LRRK2
Whole-brain mapping of basal forebrain cholinergic neurons reveals a long-range reciprocal input-output loop between distinct subtypes
A robust expression system reveals distinct gating mechanisms and calmodulin regulation of NaV1.9 channels
Proteomic signatures of corona and herpes viral antibodies identify IGDCC4 as a mediator of neurodegeneration
Coding principles of dopaminergic transmission modes
Immune cell infiltration into brain tumor microenvironment is mediated by Rab27-regulated vascular wall integrity
Neuronal lipofuscinosis caused by Kufs disease/CLN4 DNAJC5 mutations but not by a CSPα/DNAJC5 deficiency
Astrocyte-derived CCL5-mediated CCR5+ neutrophil infiltration drives depression pathogenesis
Capturing structural intermediates in an animal-like cryptochrome photoreceptor by time-resolved crystallography
Optimal focused ultrasound lesion location in essential tremor
Niemann Pick C1 mistargeting disrupts lysosomal cholesterol homeostasis contributing to neurodegeneration in a Batten disease model
In situ protein corona–camouflaged supramolecular assemblies remodel thrombotic microenvironment for improved arterial homeostasis
A neuroimmune pathway drives bacterial infection
Supervised and unsupervised learning reveal heroin-induced impairments in astrocyte structural plasticity
Biomimetic elasticity compressed assembly controls rapid intracerebral drug release to reverse microglial dysfunction
Characterizing the expression profile of 3R tau pathology in Pick’s disease
29
Autophagosome-targeting single-domain antibody clears tau in patient-derived neurons and improves motor function in tauopathy mice
Foldamers rescue synucleinopathy phenotypes in multiple in vitro and in vivo models
Engineered zinc finger repressors induce a prolonged and selective repression of SCN9A in nociceptors of nonhuman primates
Blood-brain barrier disruption, traumatic encephalopathy, and cognitive decline in retired athletes
Lowering the HTT1a transcript as an effective therapy for Huntington’s disease in a knockin mouse model
Selective targeting of mutant huntingtin intron 1 improves rescue provided by antisense oligonucleotides in Huntington’s disease mice
BDNF Val66Met protects oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer
Levetiracetam prevents Aβ production through SV2a-dependent modulation of APP processing in Alzheimer’s disease models
Skin thermal dynamics and hypothalamic thermosensitivity dissociate REM sleep and cataplexy in narcolepsy
In silico screening and preclinical validation identify bavisant as a therapeutic candidate for multiple sclerosis
Brain-derived tau for monitoring brain injury in acute ischemic stroke
Targeting brain hubs of ictal fast ripple activity to reduce seizures in patients with drug-resistant epilepsy
Reconnecting the vagus nerve to the heart through nerve conduit preserves cardiac function in a minipig model of right cardiac vagotomy
An orally bioavailable MrgprX1-positive allosteric modulator alleviates certain neuropathic pain–related behaviors in humanized mice
Loss of PILRA promotes microglial immunometabolism to reduce amyloid pathology in cell and mouse models of Alzheimer’s disease
Failure of nerve regeneration in mouse models of diabetes is caused by p35-mediated CDK5 hyperactivity
Leukocyte-intrinsic ER stress responses contribute to chemotherapy-induced peripheral neuropathy
LRRC8A constitutively inhibits pain hypersensitivity in rodent models by restraining NMDA receptor activity at spinal cord synapses
Deletion of the X-chromosomal gene Kdm6a in microglia of female mice ameliorates neuroinflammation and restores translatome profiles
Deletion of murine Sarm1 results in a microenvironment that delays peripheral nerve regeneration after injury
Immune signatures link myelin oligodendrocyte glycoprotein antibody–associated disease to other autoantibody-mediated conditions
SV2A-PET imaging uncovers cortical synapse loss in multiple sclerosis
Hippocampal spreading depolarization as a driver of postictal ambulation
Type I interferon limits central nervous system autoimmunity by modulating the microRNA-21–FOXO1 axis in pathogenic T helper 17 cells
Bezafibrate improves mitochondrial function, blood-brain barrier integrity, and social deficits in models of 22q11.2 deletion syndrome
Microglial pruning of glycinergic synapses disinhibits spinal PKCγ interneurons to drive pain hypersensitivity in mice
Interferon regulatory factor-1–expressing astrocytes are epigenetically controlled and exacerbate TBI-associated pathology in mice
MEK1/2 inhibitors suppress pathological α-synuclein and neurotoxicity in cell models and a humanized mouse model of Parkinson’s disease
Intra-amniotic antisense oligonucleotide treatment improves phenotypes in preclinical models of spinal muscular atrophy
3
Accelerated continuous theta burst stimulation targeting left primary motor cortex for children with autism spectrum disorder: multicentre randomised sham controlled trial
Edaravone dexborneol versus placebo on functional outcomes in patients with acute ischaemic stroke undergoing endovascular thrombectomy (TASTE-2): randomised controlled trial
Incidence and prevalence of dementia among US Medicare beneficiaries, 2015-21: population based study
6
Ubiquilin-2 liquid droplets catalyze α-synuclein fibril formation.
Direct interaction between TDP-43 and Tau promotes their co-condensation, while suppressing Tau fibril formation and seeding
ALS-associated RNA-binding proteins promote UNC13A transcription through REST downregulation.
Tau uptake by human neurons depends on receptor LRP1 and kinase LRRK2
Optochemical profiling of NMDAR molecular diversity at synaptic and extrasynaptic sites.
Amyloid-β disrupts APP-regulated protein aggregation and dissociation from recycling endosomal membranes.
8
Elucidation of Structural Fluctuation for Initial Signaling and DNA Recognition for Damage Repair of a Bifunctional Cryptochrome
Persistent Orbital Magnetism from Light-Induced Attosecond Charge Migration in Linear Molecules
A Charge-Reversal Point Mutation Completely Depletes Flavin Chromophore from European Robin Cryptochrome 4a Protein
Pathological Folding of α-Synuclein on Polystyrene Nanoplastic Revealed by Sum Frequency Scattering and 2D Infrared Spectroscopy
Multiscale Simulation of Photoinduced Electron Transfer in Cryptochrome 4 from European Robin and Pigeon Indicates a Conserved Dynamics
Spin-Correlated Radical Pairs as Magnetic Switches for Controlling Emissive Triplet States via Triplet–Triplet Energy Transfer
Thermodynamics Analysis of a Reaction-Diffusion Matrix Multiplication Computing Unit under the Linear Non-Equilibrium Regime
Alternative Photoreduction Pathway Involving Electron Tunneling and Proton Transfer in a Bifunctional Cryptochrome
7
Efficacy and safety of oral semaglutide 14 mg (flexible dose) in early-stage symptomatic Alzheimer's disease (evoke and evoke+): two phase 3, randomised, placebo-controlled trials
Efficacy and safety of minocycline in patients with acute ischaemic stroke (EMPHASIS): a multicentre, double-blind, randomised controlled trial
Effect of repurposed simvastatin on disability progression in secondary progressive multiple sclerosis (MS-STAT2): a phase 3, randomised, double-blind, placebo-controlled trial
Risk markers for sudden unexpected death in epilepsy: an observational, prospective, multicentre cohort study
Surgery versus corticosteroid injection for carpal tunnel syndrome (DISTRICTS): an open-label, multicentre, randomised controlled trial
Safety and efficacy of low-intensity versus standard monitoring following intravenous thrombolytic treatment in patients with acute ischaemic stroke (OPTIMISTmain): an international, pragmatic, stepped-wedge, cluster-randomised, controlled non-inferiority trial
Efficacy and safety of low-dose IL-2 as an add-on therapy to riluzole (MIROCALS): a phase 2b, double-blind, randomised, placebo-controlled trial
1
The burden of stroke, ischaemic heart disease, and dementia in Africa, 1990–2021: an ecological analysis of the Global Burden of Disease 2021
11
Door-in-door-out times and outcomes in patients with acute ischaemic stroke transferred for endovascular therapy in the USA: a retrospective cohort study
Safety and efficacy of crenezumab in cognitively unimpaired carriers of the PSEN1 Glu280Ala mutation at risk for autosomal-dominant Alzheimer's disease in Colombia (API ADAD Colombia Trial): a phase 2, randomised, double-blind, placebo-controlled trial
Azathioprine for the treatment of early Parkinson's disease (AZA-PD): a randomised, double-blind, placebo-controlled, proof-of-concept, phase 2 trial
Seizure-related biomarkers of sudden unexpected death in epilepsy (SUDEP) in drug-resistant focal epilepsy (REPO2MSE): a prospective, multicentre case–control study
Intravenous alteplase versus oral aspirin for acute central retinal artery occlusion within 4·5 h of severe vision loss (THEIA): a multicentre, double-dummy, patient-blinded and assessor-blinded, randomised, controlled, phase 3 trial
Neuropathological changes and amyloid-related imaging abnormalities in Alzheimer's disease treated with aducanumab versus untreated: a retrospective case–control study
Sleep EEG and respiratory biomarkers of sudden unexpected death in epilepsy (SUDEP): a case–control study
Association between the Edinburgh CT and genetic diagnostic criteria for cerebral amyloid angiopathy-associated lobar intracerebral haemorrhage and recurrent intracerebral haemorrhage: an individual patient data meta-analysis
Safety and efficacy of apitegromab in nonambulatory type 2 or type 3 spinal muscular atrophy (SAPPHIRE): a phase 3, double-blind, randomised, placebo-controlled trial
Diagnostic and prognostic value of α-synuclein seed amplification assay kinetic measures in Parkinson's disease: a longitudinal cohort study
Effects of blood pressure lowering in relation to time in acute intracerebral haemorrhage: a pooled analysis of the four INTERACT trials
2
The distinctive psychopathology of NMDAR-antibody encephalitis compared with primary psychoses: an international, multicentre, retrospective phenotypic analysis
Theta burst stimulation of temporo-parietal cortex regions for the treatment of persistent auditory hallucinations: a multicentre, randomised, sham-controlled, triple-blind phase 3 trial in Germany
10
Asundexian for Secondary Stroke Prevention
Zorevunersen in Children and Adolescents with Dravet Syndrome
An Antibody–Oligonucleotide Conjugate for Myotonic Dystrophy Type 1
A Randomized Trial of Tenecteplase in Acute Central Retinal Artery Occlusion
Fremanezumab in Children and Adolescents with Episodic Migraine
A Randomized Trial of Shunting for Idiopathic Normal-Pressure Hydrocephalus
Risdiplam in Presymptomatic Spinal Muscular Atrophy
Early Tirofiban Infusion after Intravenous Thrombolysis for Stroke
Intravenous Tenecteplase before Thrombectomy in Stroke
Oveporexton, an Oral Orexin Receptor 2–Selective Agonist, in Narcolepsy Type 1
1
Health trajectories of patients with amyotrophic lateral sclerosis before and after initiation of non-invasive ventilation: a French nationwide database analysis

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