Nature Search

Assessment of extreme climate trends using temperature, rainfall, and cyclones in the West Bengal coastal region

Mousumi Dey
Vinod K. Bhardwaj
ResearchOpen Access06 Oct 2025
Scientific Reports

Volume: 15, P: 1-19
Computational design of generalist cyclopropanases with stereodivergent selectivity

Despite advances in enzyme design and engineering, the development of biocatalysts featuring a combination of tailored stereoselectivity with broad substrate scope has been very difficult. Focusing on a new-to-nature reaction, the authors report a mechanism-based, multi-state computational design workflow for the generation of ‘generalist’ cyclopropanases capable of transforming a broad range of substrates with tailored and divergent stereoselectivity.

Zhuofan Shen
Mary G. Siriboe
Rudi Fasan
ResearchOpen Access26 Jan 2026
Nature Communications

P: 1-16
Dual promoter–enhancer activities reflect a unified regulatory logic

This study shows that promoter and enhancer functions are often linked within the same DNA sequences. Using a dual-reporter assay, the authors reveal shared sequence features and co-dependent activities supporting a unified model of gene regulation.

Mauricio I. Paramo
Alden King-Yung Leung
Haiyuan Yu
ResearchOpen Access30 Jan 2026
Nature Communications

P: 1-18
Effect of high shear-dispersed nano-alumina on concrete strength, durability, and microstructure

Ibadur Rahman
Nirendra Dev
M. Masroor Alam
ResearchOpen Access28 Jan 2026
Scientific Reports

P: 1-23
Precipitation isotopes and monsoon dynamics in the core monsoon zone of India

Supriyo Chakraborty
Aharna Sarkar
Anupam Sharma
ResearchOpen Access25 Feb 2025
Scientific Reports

Volume: 15, P: 1-16
Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990–2023: a Global Burden of Disease Study

Global Burden of Disease estimates show that between 1990 and 2023, the prevalence and burden of drug use disorders, inclusive of amphetamine, cannabis, cocaine and opioid use, have been increasing in high-income countries, particularly in the USA.

Jiseung Kang
Hyeon Jin Kim
Dong Keon Yon
Research16 Jan 2026
Nature Medicine

P: 1-18
Tailoring Ba₃PCl₃-based perovskite solar cells via multi-parameter optimization for high power conversion efficiency

Sagar Bhattarai
Roshni Banthia
Suddhendu DasMahapatra
ResearchOpen Access27 Jan 2026
Scientific Reports

P: 1-19
Probing into the binding mechanism of phosphorus(V)-corrole with hemoglobin using photophysical and computational approach

Kritika
Ritika Kubba
Indrajit Roy
ResearchOpen Access23 Jan 2026
Scientific Reports

P: 1-15
Hybrid deep learning model for air quality prediction and its impact on healthcare

Tanisha Madan
Shrddha Sagar
Arvind Panwar
ResearchOpen Access23 Jan 2026
Scientific Reports

P: 1-17
The human brain modulates sniffs according to fine-grained perceptual features of odours

Sagar et al. show that human sniff behaviour is sensitive to the perceptual characteristics of the odour being detected.

Vivek Sagar
Andrew Sheriff
Christina Zelano
Research12 Nov 2025
Nature Human Behaviour

Volume: 10, P: 137-147
Native diversity buffers against severity of non-native tree invasions

Analysis combining multiple global tree databases reveals that whether a location is invaded by non-native tree species depends on anthropogenic factors, but the severity of the invasion depends on the native species diversity.

Camille S. Delavaux
Thomas W. Crowther
Daniel S. Maynard
ResearchOpen Access23 Aug 2023
Nature

Volume: 621, P: 773-781
Expert retrospective on a decade of the Paris Agreement

To mark the tenth anniversary of the Paris Agreement, Nature Climate Change asked experts to reflect on the progress of and barriers to several of its key Articles. They share their thoughts on important policy implications, what has been achieved and missed, as well as future directions.

Carl-Friedrich Schleussner
Paula Castro
Thomas Bernauer
Reviews05 Nov 2025
Nature Climate Change

Volume: 15, P: 1136-1140
Policy drivers for clean-energy technology 2025

Despite uncertainly around climate-focused policy, the policy outlook for clean-energy technologies remained resilient in 2025, owing to the cost-competitiveness of key technologies combined with emerging priorities relating to energy security, data centres, defence and economic opportunities.

Ambuj D. Sagar
Simon Bennett
News & Views20 Jan 2026
Nature Reviews Clean Technology

Volume: 2, P: 2-3
Hourglass-shaped GaAs_0.99Bi_0.01 nanowire solar cells with CuI-PEDOT:PSS double hole transport layers for enhanced photovoltaic performance

Manisha Rautela
Sumit Sagar
Jitendra Kumar
ResearchOpen Access07 Jan 2026
Scientific Reports

P: 1-11
A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma

Pilcher et al. present a single-cell transcriptomics-based immune atlas of participants with newly diagnosed multiple myeloma, reporting on the association of cell types, gene expression and intercellular interactions with disease progression phenotypes.

William C. Pilcher
Lijun Yao
Manoj Bhasin
ResearchOpen Access09 Jan 2026
Nature Cancer

P: 1-23
Earthworms and Seeds

M. MCRILL
G. R. SAGAR
Research01 Jun 1973
Nature

Volume: 243, P: 482
Switch-like enhancement of epithelial-mesenchymal transition by YAP through feedback regulation of WT1 and Rho-family GTPases

Reorganisation of the extracellular matrix (ECM) controls processes involving epithelial-mesenchymal transition (EMT). Here, the authors show that EMT occurring in epithelial cells on a fabricated nano-engineered cell adhesion surface is triggered by mechanical cues from the ECM.

JinSeok Park
Deok-Ho Kim
Andre Levchenko
ResearchOpen Access26 Jun 2019
Nature Communications

Volume: 10, P: 1-15
Efficacy of CTLA-4 checkpoint therapy is dependent on IL-21 signaling to mediate cytotoxic reprogramming of PD-1⁺CD8⁺ T cells

Here the authors dissect the contribution of IL-21 signaling to immune checkpoint-responding CD8⁺ T cells from mouse models and patients being treated for advanced melanoma.

Zhen Zhang
Marlene Langenbach
Bertram Bengsch
Research19 Dec 2024
Nature Immunology

Volume: 26, P: 92-104
Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
Author Correction: Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution

Takahiro Masuda
Roman Sankowski
Marco Prinz
Amendments and Corrections27 Mar 2019
Nature

Volume: 568, P: E4
Electrocatalytic continuous flow chlorinations with iodine(I/III) mediators

Electrochemistry offers tunable, cost effective and environmentally friendly alternatives to carry out redox reactions but the use of organoiodine compounds as electrocatalysts is largely underdeveloped. Here, the authors report an environmentally benign iodine(I/III) electrocatalytic platform for the in situ generation of dichloroiodoarenes for different reactions within a continuous flow setup.

Tuhin Patra
Sagar Arepally
Thomas Wirth
ResearchOpen Access27 Jul 2024
Nature Communications

Volume: 15, P: 1-8
A transformer guided multi modal learning framework for predictive and causal assessment of thermal runaway in high energy batteries

Sameer Sheshrao Gajghate
Muhamad Mat Noor
Milon Selvam Dennison
ResearchOpen Access23 Oct 2025
Scientific Reports

Volume: 15, P: 1-20
Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018

Geospatial estimates of the prevalence of anemia in women of reproductive age across 82 low-income and middle-income countries reveals considerable heterogeneity and inequality at national and subnational levels, with few countries on track to meet the WHO Global Nutrition Targets by 2030.

Damaris Kinyoki
Aaron E. Osgood-Zimmerman
Simon I. Hay
ResearchOpen Access12 Oct 2021
Nature Medicine

Volume: 27, P: 1761-1782
Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP

Chagas disease, caused by Trypanosoma cruzi, lacks an effective vaccine. Here, the authors report the cryo-EM structure of TcPOP, a potential vaccine antigen, in open and closed states and validate its immunogenic potential for invasion-blocking antibodies.

Sagar Batra
Francisco Olmo
Ivan Campeotto
ResearchOpen Access05 Aug 2025
Nature Communications

Volume: 16, P: 1-16
Evolutionary trends in the Indian Iseilema

Y. SUNDAR RAO
Research15 May 1975
Nature

Volume: 255, P: 220-221
Multimodal profiling reveals site-specific adaptation and tissue residency hallmarks of γδ T cells across organs in mice

Sagar and colleagues provide a comprehensive single-cell multimodal landscape of γδ T cells in various mouse tissues, unveiling site-specific adaptations and highlighting key tissue residency features of γδ T cells.

Anastasia du Halgouet
Kerstin Bruder
Sagar
ResearchOpen Access04 Jan 2024
Nature Immunology

Volume: 25, P: 343-356
A droplet microfluidics-based platform for generating target-specific, natively-paired immune libraries and identifying potent and developable antibodies

Anusuya Ramasubramanian
Brendan T. Deveney
John A. Heyman
ResearchOpen Access03 Jan 2026
Scientific Reports

Volume: 16, P: 1-22
Heterogeneity of poly(I).poly(C)-induced human fibroblast interferon mRNA species

Pravinkumar B. Sehgal
Anurag D. Sagar
Research06 Nov 1980
Nature

Volume: 288, P: 95-97
The effect of magnetic fields on γ-ray bursts inferred from multi-wavelength observations of the burst of 23 January 1999

T. J. Galama
M. S. Briggs
D. Bhattacharya
Research01 Apr 1999
Nature

Volume: 398, P: 394-399
Emergence of slip-ideal-slip behavior in tip-links serve as force filters of sound in hearing

In this work, the authors report that tetrameric tip-link complex, pivotal for force transmission, forms slip-ideal-slip bonds under tension, serving as efficient force-filters in the auditory process.

Nisha Arora
Jagadish P. Hazra
Sabyasachi Rakshit
ResearchOpen Access21 Feb 2024
Nature Communications

Volume: 15, P: 1-13
Midkine attenuates amyloid-β fibril assembly and plaque formation

Zaman, Yang and Huang et al. demonstrate MDK’s suppressive effect on amyloid-β and its impact on amyloid burden and microglial activation in Alzheimer disease mice, highlighting its protective role in pathogenesis.

Masihuz Zaman
Shu Yang
Junmin Peng
Research21 Aug 2025
Nature Structural & Molecular Biology

Volume: 32, P: 2165-2175
Future climate-driven fires may boost ocean productivity in the iron-limited North Atlantic

Fire emissions can be an important source of nutrients such as iron, particularly for the oceans. Here the authors estimate that climate-change-driven changes in fire emissions could increase iron deposition in ocean ecosystems, enhancing productivity particularly in the North Atlantic.

Elisa Bergas-Masso
Douglas S. Hamilton
Carlos Pérez García-Pando
ResearchOpen Access13 Jun 2025
Nature Climate Change

Volume: 15, P: 784-792
HIV-1 Vpr suppresses immune activation and apoptosis through regulation of nuclear factor κB

Velpandi Ayyavoo
Artin Mahboubi
David B. Weiner
Research01 Oct 1997
Nature Medicine

Volume: 3, P: 1117-1123
Surface functionalized albumin nanoparticles of palbociclib with amplified brain delivery for treating brain glioblastoma

Vishwanath Kurawattimath
Barnabas Wilson
Kalpana Divekar
ResearchOpen Access04 Aug 2025
Scientific Reports

Volume: 15, P: 1-16
Macromolecular modeling and design in Rosetta: recent methods and frameworks

This Perspective reviews tools developed over the past five years in the macromolecular modeling, docking and design software Rosetta.

Julia Koehler Leman
Brian D. Weitzner
Richard Bonneau
Reviews01 Jun 2020
Nature Methods

Volume: 17, P: 665-680
On the safe side of pesticides

G.R. Sagar
Books & Arts10 Mar 1983
Nature

Volume: 302, P: 174-175
Key frame extraction based abnormal vehicle identification technique using statistical distribution analysis

M. A. Y. Peer Mohamed Appa
V. Vanitha
M. Asha Paul
ResearchOpen Access22 Aug 2025
Scientific Reports

Volume: 15, P: 1-9
All polymer ligand strategy enables highly stable spectra-pure green-emitting perovskites

Akash V. Fulari
Sagar E. Shirsath
Gaurav M. Lohar
ResearchOpen Access25 Aug 2025
Scientific Reports

Volume: 15, P: 1-11
Ensemble machine learning models for predicting strength of concrete with foundry sand and coal bottom ash as fine aggregate replacements

Sagar Paruthi
Rashmi Verma
Mohd Abul Hasan
ResearchOpen Access03 Nov 2025
Scientific Reports

Volume: 15, P: 1-19
Astrocyte-to-neuron H₂O₂ signalling supports long-term memory formation in Drosophila and is impaired in an Alzheimer’s disease model

Rabah et al. discover an astrocyte-to-neuron hydrogen peroxide signalling cascade, which is crucial for long-term memory formation in Drosophila. This signalling is found to be inhibited by amyloid-β peptide, suggesting a link to Alzheimer’s disease.

Yasmine Rabah
Jean-Paul Berwick
Thomas Preat
ResearchOpen Access24 Jan 2025
Nature Metabolism

Volume: 7, P: 321-335
An integrated AI-driven framework for maximizing the efficiency of heterostructured nanomaterials in photocatalytic hydrogen production

Pramod N. Belkhode
Shrikant M. Awatade
Milon Selvam Dennison
ResearchOpen Access10 Jul 2025
Scientific Reports

Volume: 15, P: 1-19
Structural basis for C-degron selectivity across KLHDCX family E3 ubiquitin ligases

Kelch-domain KLHDCX E3 ligases bind substrate C-terminal glycines. This study reveals substrate selectivity by E3s with similar structures; C-degrons are perceived by a “C-terminus anchor motif”, whose display on different Kelch propeller blades along with distal interactions establish specificity.

Daniel C. Scott
Sagar Chittori
Brenda A. Schulman
ResearchOpen Access15 Nov 2024
Nature Communications

Volume: 15, P: 1-17
Effect of climate on traits of dominant and rare tree species in the world’s forests

Species’ traits and environmental conditions determine the abundance of tree species across the globe. Here, the authors find that dominant tree species are taller and have softer wood compared to rare species and that these trait differences are more strongly associated with temperature than water availability.

Iris Hordijk
Lourens Poorter
Thomas W. Crowther
ResearchOpen Access22 May 2025
Nature Communications

Volume: 16, P: 1-15
Deciphering the folding code of collagens

Collagen triple helices are found in all the three domains of life as well as viruses. Here, the authors show that collagens have converged on a similar folding mechanism that employs salt bridge interactions to guide the triple helix assembly.

Jean-Daniel Malcor
Noelia Ferruz
Abhishek A. Jalan
ResearchOpen Access19 Mar 2025
Nature Communications

Volume: 16, P: 1-19
The subfornical organ is a nucleus for gut-derived T cells that regulate behaviour

A distinct population of CD4 T cells resides in specific regions of the steady-state brain, and these T cells are programmed in the periphery by the microbiome to coordinate adaptive behaviour.

Tomomi M. Yoshida
Mytien Nguyen
Andrew Wang
Research28 May 2025
Nature

Volume: 643, P: 499-508
Multiscale tumor characterization in histopathology via self-distilled transformers and topology-aware visual encoding

Tanvir H. Sardar
P. Naresh
B. M. Ahamed Shafeeq
ResearchOpen Access16 Dec 2025
Scientific Reports

Volume: 15, P: 1-14
Therapeutic evaluation of Martynia annua derived carbon dots in epileptic Drosophila model

Megha B. Abbigeri
Muskan Khan
Yarajarla Ramesh Babu
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-21
Memory-like HCV-specific CD8⁺ T cells retain a molecular scar after cure of chronic HCV infection

Thimme and colleagues identify a molecular signature of T cell exhaustion resembling a ‘chronic scar’ that is imprinted in hepatitis C virus–specific CD8⁺ T cells and cannot simply be reversed by viral clearance.

Nina Hensel
Zuguang Gu
Maike Hofmann
Research04 Jan 2021
Nature Immunology

Volume: 22, P: 229-239
HLA3DB: comprehensive annotation of peptide/HLA complexes enables blind structure prediction of T cell epitopes

Structure prediction of peptide/HLA (pHLA) complexes has been mired by the inability to accurately model the middle of the peptide. Here, the authors present a curated database of pHLA structures (HLA3DB) and identify discrete peptide backbone conformations that are used for high fidelity modelling.

Sagar Gupta
Santrupti Nerli
Nikolaos G. Sgourakis
ResearchOpen Access10 Oct 2023
Nature Communications

Volume: 14, P: 1-13
Integrated biochar and Lemna minor system for sustainable remediation of Benzophenone-3 from wastewater

Shamika Shantaram Sawant
Vidya Shree Bharti
Sagar Shinde
ResearchOpen Access18 Nov 2025
Scientific Reports

Volume: 15, P: 1-13

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