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Emu3 enables large-scale text, image and video learning based solely on next-token prediction, matching the generation and perception performance of task-specific methods, with implications for the development of scalable and unified multimodal intelligence systems.

Shape-changing substrates are pivotal for advancing minimally invasive, conformable bioelectronics, yet their implantation is hindered by inaccessible triggering mechanisms and complex geometric fabrication. Here, the authors report a digital 4D printing technique for fabricating customized shape memory hydrogel substrates enabling trigger-free shapeshifting with predefined onset periods.

Lithium metal negative electrodes have great potential for high-specific energy batteries. However, dendrite growth, due to limited Li⁺ transport at the Li metal interface, results in low reversibility and safety concerns. Here, the authors developed a nanofluidic artificial interfacial layer to enhance interfacial Li⁺ transport, prevent Li⁺ depletion, and ensure uniform Li deposition.

Conventional design of perovskite heterojunctions face challenges in precisely controlling interfacial phase purity at nanoscale. Here, the authors introduce dimethyl sulfide as a soft Lewis base additive in organic cation solution, achieving certified efficiency of 26.48% in stable solar cells.

Incorporating CO₂ into propane dehydrogenation (PDH) offers great potential for propylene production while simultaneously utilizing greenhouse gases; however, a key challenge is suppressing the undesired dry reforming of propane. Here, the authors present a coupled strategy that combines PDH with the reverse water–gas shift reaction through a tandem catalytic system.

Decreasing salt-to-solvent molar ratio without sacrificing electrochemical performance remains a challenge in high-performance lithium metal batteries. Here, authors show that compatibility of fluorobenzene-diluted 1,2-dimethoxyethane-based electrolyte with Li metal is reduced in smaller salt-to-solvent molar ratios and design a fluorobenzene-diluted dimethyl acetal-based electrolyte with significantly enhanced stability towards Li metal under a reduced Li salt concentration.

Phenolic compounds have long captivated the interest of organic synthesis, particularly in their quest for selective hydroxylation of arenes using H₂O as a hydroxyl source but the inherent high reactivity and low redox potential of phenols often lead to undesirable overoxidation byproducts. Here the authors develop an electrophotochemical approach, finetuning substrate oxidative potential and enabling para-selective hydroxylation of anilides.

The upscaling of kesterite photovoltaics is challenging and results in low performance. Xiang et al. tune the thiourea/metal precursor ratio to improve the morphology of the kesterite film, achieving 10.1% certified power conversion efficiency in 10.48-cm² modules.

FcγRIIb captures its ligand and targets it to lysosomal degradation following endocytosis. Here authors design bispecific-antibody-like molecules they call FcγRIIb-targeting chimeras or FcRTACs, to capture antigens with one arm and degrade them via an FcγRIIb-binding second arm to promote the clearance of pathological protein aggregates.

Cross-linkable co-SAMs improve hole-selective SAM stability, preventing defects and thermal degredation in perovskite solar cells, enabling 26.92% efficiency with high heat durability, and guiding the design of more efficient and durable solar cells.

Calcium-ion batteries are potentially attractive alternatives to lithium-ion batteries, but remain largely unexplored because of low performance. A reversible calcium alloying/de-alloying reaction with the tin anode has now been coupled with the intercalation/de-intercalation of hexafluorophosphate in the graphite cathode to enable a calcium-ion battery that operates stably at room temperature.

Gong et al. report an all-perovskite photovoltaic-powered battery using ethyl viologen diiodide and its derivative to modify the perovskite solar cell and the battery cathode, enabling an overall energy conversion efficiency of 18.54%. The flexible version powers a wearable glucose monitor for 24 h.

The transition of perovskite solar cells from laboratory research to industrial-scale production creates an important opportunity to prioritize sustainability. This Review introduces a closed-loop framework, addressing material sourcing, fabrication methods, solvent design, lead-risk mitigation, recycling strategies and future directions.

High-temperature, ultrathin, and high-performance microwave absorption is realized in the dual-layer structure with rare earth zirconate ceramics via electron delocalization-mediated thermionic migration and macroscopic interfacial resonance.

A new p-type small molecule enhances defect passivation and improves interfacial charge transport in perovskite solar cells, enabling devices with a certified power conversion efficiency of 26.72%, 97% of which is maintained after 2,500 h of continuous operation.

Pure CuInSe₂ solar cells suffer from strong interfacial carrier recombination. Here, the authors introduce a wide U-shaped double Ga grading with a minimum bandgap of 1.01 eV and achieve certified device efficiency of 20.26%, making it highly suitable for tandem solar cell applications.

An ideal thermoelectric material has a large Seebeck coefficient, and a high electrical but low thermal conductivity; however, optimizing all three is difficult. Zhao et al. discover three types of coexisting multi-localization transport behaviours in filled skutterudite materials that aid this optimization.

Traditional luminescent solar concentrators generally require separated energy storage modules limiting applications in smart windows. Here, authors propose an integration between luminescent solar concentrators and electrochromic supercapacitors capable of photovoltaic conversion, energy storage, and electrochromism.

Quasi-solid-state polymer electrolytes are ideal candidates for practical secondary battery applications. Here, the authors propose a negatively charged (–COO^–)-modified covalent organic framework as a Na-ion quasi-solid-state electrolyte with sub-nanometric Na-ion transport zones.

Improving the manufacturability of perovskite solar cells is key to their deployment. Zheng et al. report a one-step deposition of the hole-selective and absorber layers that addresses wettability issues and simplifies the fabrication process.

The large organic cations in low-dimensional perovskite often introduces carrier mobility anisotropy and impedes charge transport. Here, authors report perovskite heterojunction with strong aromatic conjugated perovskites, realizing certified efficiency of over 25% in stable perovskite solar cells.

Understanding the local microenvironment is crucial yet challenging for catalyst design. Here, the authors demonstrate that the nanoconfined environment of carbon nanotubes enriches CO and induces structural deformation in cobalt phthalocyanine, thereby promoting CO₂ electroreduction to methanol.

Growing use of ionizing radiation in medicine and industry has increased risk of radiation exposure and injury. Here, Deng et al. utilize molecular engineering of melanin to develop a panel of metal-free melanin materials for shielding against γ-ray radiation.

A deep learning algorithm using electronic health records from two large cohorts of patients predicts the risk of pancreatic cancer from pre-cancer disease trajectories up to 3 years in advance, showing promising performance in retrospective validation.

Researchers decreased the recombination rate in lead-halide perovskite thin films by using plasmonic mirrors and hyperbolic metamaterials. The findings led to a 250% photodetector photoresponsivity increase and may have implications for other optoelectronic devices.

Interpretable machine learning offers a powerful method for accelerating catalyst design. Here the authors report an interpretable descriptor model to unify activity and selectivity prediction for multiple electrocatalysis using only easily accessible intrinsic properties.

A MoO₃-Fe₂O₃ redox catalyst with dispersed Mo species on γ-Fe₂O₃ is synthesized for the oxidative dehydrogenation of propane via chemical looping. Acid sites and lattice oxygen regulation promote the production of and selectivity for propylene.

Dense atomic-scale 2D/2D Schottky heterojunctions are achieved in the graphene-based superlattice nanocomposites by controlled deintercalation, largely facilitating spatial charge separation that optimizes their microwave-absorbing performance.

The mechanism of how interfacial wettability impacts the CO₂ electcgq Herein, the authors describe the design and realization of controllable equilibrium of kinetic controlled *CO and *H to reveal its contribution to ethylene and ethanol pathways.

Debiasi et al. examine glioblastoma in the edema region of the tumor, by computing the tissue magnetic properties using MRI data to develop a method to automatically identify areas indicative of infiltration. Association is demonstrated between magnetic properties and tumor prognostic factors, which is caused by an elevated iron presence in the tumor tissues.

Intermetallic alloys (IMAs) hold significant potential for catalysis. Here, the authors present a robust gas-migration method for synthesizing stable and uniform IMAs, which exhibit exceptional stability over 1300 h in propane dehydrogenation.

Preparation of inorganic protective layers for photoelectrodes requires high-quality deposition techniques. Here, the authors report a spin-coated organic protective layer that enables Si photocathodes to realize stable solar water splitting.

Mass balance measurements from inland East Antarctica suggest a negative trend in surface mass balance from 2005 to 2020, probably associated with enhanced zonal winds.

The catalytic partial oxidation of methane (POM) is a promising technology for synthesizing syngas but suffers from severe over-oxidation on the catalyst surface. Here the authors demonstrate that regulating O* occupation in an atomically dispersed MoNi alloy can achieve high catalytic performance for POM.

Designing an efficient activation function for optical neural networks remains a challenge. Here, the authors demonstrate a modulator-detector-in-one graphene/silicon heterojunction ring resonators enabling on-chip reconfigurable activation function devices with phase activation capability for optical neural networks.

Carnosine is a mobile buffering metabolite. Here the authors link carnosine accumulation, hypoxia and intracellular pH homeostasis in cancer cells as a mechanism of tumor immune evasion via NFX1 degradation and galectin-9 activity.

Neurons in the dorsal motor nucleus of vagus are involved in the absorption of fat in the intestine, and the natural compound puerarin shows utility in modulating this brain–gut axis to reduce fat absorption.

Tea is an important beverage crop with a large and heterozygous genome. Here, the authors assemble the genome of the cultivar Longjing 43 and conduct a population genetics study to reveal divergent selection for disease resistance and flavor between the two variety groups.

Shukla and colleagues study the genomic and transcriptomic data of exceptional responders to immunotherapy in renal cell carcinoma and find that such responses could be related to tertiary lymphoid structures, clonal neoantigen load and altered metabolism.

Polyoxyanion compounds are alternative cathodes to conventional oxides, but their reliance on the transition metal redox limits the performance. Here the authors report an oxalate system which possesses additional polyanionic redox reactivity, suggesting a new direction for cathode materials design.

Probing the interfacial structure of catalysts under CO₂ electrolysis is crucial. Here, the authors report a well-defined bimetallic silver-copper heterostructure to unravel an intermediate-regulated interfacial restructuring behavior, which promotes CO₂ electroreduction to multi-carbon products.

On-chip optoelectronic devices are promising to build compact and efficient distributed acoustic sensing (DAS) systems. Here, the authors demonstrate an ultra-high extinction ratio electro-optical modulator on silicon and its application for DAS.

A combination of hardware developments has increased the achievable spatial resolution in 7 Tesla human neuroimaging to about 0.4 mm.

Ceruloplasmin has an important role in the stabilization and nuclear transport of HIF-1α, thus regulating VEGF expression. Here the authors show that the transcription factor SARI reduces colorectal cancer growth and angiogenesis in vivoby inducing the degradation of ceruloplasmin, thereby inhibiting the HIFα/VEGF axis.

Transparent YAG crystals are ubiquitous in phosphors, scintillators and lasers, but are complex and costly to make. Here, the authors use a one-step pressureless crystallization of bulk glass to make a transparent biphasic YAG nanoceramic that can be doped for optical applications.

Using intracranial recordings in pairs of humans cooperating in interactive games, this study shows fine-grained cooperation dynamics featured by state-dependent motives and the intrabrain and interbrain profiles of high-gamma activity in the amygdala and temporoparietal junction.