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Painful bone growth after injury or surgery often goes undetected until it is advanced and treatment options are limited. Here, authors demonstrate that a blood test detecting gene expression profiles in isolated circulating mesenchymal progenitor cells could detect early signs of this condition and track treatment success.

The authors consider the changing sensitivity of the leaf-onset date to temperature (S_T) for boreal deciduous broadleaf forests. S_T increased between 1982–1996 and 1998–2012—potentially linked to enhanced chilling accumulation—but this increase is underestimated in phenology models.

Magnet-free J-oscillators use internal spin-spin couplings in molecules and digital feedback to generate continuous, ultra-stable zero-field NMR signals, reaching up to 100x narrower linewidths for sharper molecular fingerprints.

Luppi et al. identify transcriptomic and connectomic controllers of information integration and its breakdown induced by anaesthesia in humans, macaques, marmosets and mice.

High-resolution flare footpoint observations in the extreme ultraviolet and X-rays were taken by Solar Orbiter. Combined with simulations, the results reveal that the dominant mechanism carrying flare energy through the Sun’s atmosphere can vary on small spatial scales.

The rational design of autonomous light-powered molecular motors remains a formidable challenge in nanoscience. Now, a photochemically driven diazene-based rotary motor has been shown to rotate around a single bond, with a preferred direction that can be reversed by changing the wavelength of the irradiation light.

Genetic mapping in mice identified Homer1a as a key modifier of attention. Developmental downregulation in the prefrontal cortex enhances inhibitory tone, neural signal to noise and adult attentional performance, revealing a new control mechanism and target.

Here the authors show that endogenous or therapeutically delivered GDF-15 activates brainstem neurons that trigger splenic β-adrenergic signaling. This, in turn, suppresses autoreactive T cells and reduces neuroinflammation, identifying a possible target for multiple sclerosis treatment.

Engineering motif-specific 'hot spots' into an antibody scaffold yields antibodies with high affinity to targets containing phosphoserine, phosphothreonine or phosphotyrosine.

A method to coherently manipulate excitons and perform all-optical logic operations using the valley degree of freedom in monolayer WS₂ is discussed.

Zygnematophycean algae are the closest algal relatives of land plants. This study compares the osmatic stress response of two of these species, finding a core set of molecular protective components and providing insights into the toolkit needed for plant terrestrialization.

The emergent electric field induced by pinned magnetic solitons remains poorly understood. Now the dissipative motion of magnetic domain walls under an alternating current in Weyl magnet NdAlSi devices is shown to induce a large emergent electric field.

It has been suggested that quantum computers could give a quadratic speedup in sampling from the stationary distribution of reversible Markov chains. Here, the authors extend the result by investigating two quantum methods for accelerating the mixing of nonreversible Markov chains.

The demonstration of unconventional unidirectional magnetoresistance in WTe₂/Cr₂Ge₂Te₆ bilayers reveals a pathway for electrical readout of perpendicular magnetic states, advancing prospects for two-terminal spintronic memory devices.

In social settings, people need to establish how much they contribute to shared outcomes. Here, the authors show that people strategically alter their actions to establish their level of control and identify neural activity underlying this process.

This study reports coherent Aharonov–Bohm interference, including statistical phase contributions, in a Fabry–Pérot interferometer at two even-denominator fractional quantum Hall states in high-mobility bilayer-graphene van der Waals heterostructures is reported.

Coordinated ground- and space-based observations of a solar flare reveal synchronized quasi-periodic pulsations in downflowing chromospheric plasma, resulting from electron acceleration modulated by repeated magnetic reconnection.

Active fluids, such as bacterial suspensions, exhibit chaotic flows at low Reynolds number - a phenomenon known as active turbulence. Here, the authors show a discontinuous transition from laminar to chaotic flows in unconfined active nematics.

Here, the authors provide evidence of the biotherapeutic potential of Klebsiella ARO112 for gut inflammatory conditions by showing it accelerates pathobiont clearance and recovery of microbiota diversity, boosting intestinal butyrate, and preventing inflammation and colitis in IBD models.

This Review extends fluctuational electrodynamics, introduced originally to deal with radiation due to thermal fluctuations, to provide a unified quantitative theoretical framework that accounts for light emission processes in solids.

Despite the potential of free electrons for quantum technological applications, these are still limited by the weak electron-photon interactions. To address this challenge, the authors introduce electron-light couplers that produce high-photon-number state generation, enabling quantum sensing and metrology with unprecedented precision.

Reliably probing rejuvenation and memory effects in spin glasses by means of simulations is difficult. Now, a state-of-the-art numerical study shows that at least three different length scales play a crucial role in aging dynamics of spin glasses.

Fano-resonant nanostructures have received interest in the sensing community due to the high local fields and narrow resonant linewidths. Here, the authors characterise subwavelength perturbations in a Fano-resonant dielectric metasurface using both a conventional spectral method and a Fourier scatterometry approach, demonstrating that perturbations induce pronounced directional scattering in Fourier space.

In this study, the authors use a combination of experimental and modeling approaches to show that a human gut bacterial community can exist in different states under the same conditions. The mechanism behind these alternative states is likely based on metabolic change in response to nutrient depletion.

Guidance on how to decarbonize the economy while limiting impacts on jobs and ensuring stability is scarce. Now a study finds that relying on a carbon tax alone falls short, whereas combining industrial regulations, subsidies and a modest tax is the most promising approach to achieve sustainable growth with green jobs.

HIV epidemic trends among female sex workers in sub-Saharan Africa are rarely known. The authors analyse HIV prevalence trends among female sex workers based in Zimbabwe and report a significant decline between 2016-2017 and 2021-2023, which may be due to increased treatment coverage among the male population.

Sodium metal is of interest for high-energy-density batteries, but the lack of large-area ultrathin sodium metal foils hinders research. Here a metre-length, ultrathin (≤50 μm), mechanically strengthened sodium metal foil is fabricated by a roll-to-roll calendaring process with interfacial lubrication and functional modification.

The authors theoretically delineate the maximal increases in tree growth that can be expected from increases in plant intrinsic water-use efficiency, which increases with rising CO₂. They highlight environmental and physiological limits on growth in the context of experimental data.

Green subsidies (carrots) are now becoming a more politically acceptable climate policy option compared with corrective regulations (sticks). However, researcher show that carrots without quick and appropriate sticks will not be sufficient to reach the deep decarbonization goal in the long run.

DNA data storage is an alternative to silicon-based data storage, but it demands advanced encryption and readout techniques. Here, the authors present an enhanced DNA origami cryptography protocol for data storage, using DNA-PAINT super-resolution imaging and unsupervised clustering to retrieve information in DNA cryptography.

Genomic analyses applied to 14 childhood- and adult-onset psychiatric disorders identifies five underlying genomic factors that explain the majority of the genetic variance of the individual disorders.

3.4-million-year-old hominin fossils discovered in Ethiopia provide insight into the diet and locomotion of Australopithecus deyiremeda.

While phytoplankton are well studied and understood at the global scale, floating macroalgae are not. This study presents a comprehensive picture of the global distributions of floating macroalgae and phytoplankton surface scums, both showing expanding trends from 2003 to 2022.

This study provides robust evidence that Arctic warming affects precipitation variability in the mid-latitudes by modulating westerly waviness. Under global warming, extreme precipitation events in midlatitude regions will become more frequent.

Diffusion models are reframed by developing a generative blood cell classifier that performs reliably in low-data regimes, adapts to domain shifts, detects anomalies with robustness and provides uncertainty estimates that surpass clinical expert benchmarks.

Artifact mutations from FFPE are a major barrier blocking WGS adoption in clinical oncology. FFPErase, a machine learning framework, eliminates these with high accuracy in multiinstitutional datasets, delivering clinical-grade variant reports.

Researchers developed a self-driving lab, including automated confocal imaging, that uses machine learning to rapidly map the phase behavior of biomolecular condensates.

Mineral carbonation could enable gigatonne-scale CO₂ removal. Here, the authors use molecular simulations to map a full CO₂ mineralization pathway at a wetting surface, revealing key reactive sites and optimal pH conditions for efficient carbonation.