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Non-Hermitian physics, like the non-Hermitian skin effect (NHSE), is well-explored in classical platforms but remains challenging in quantum systems. Here, the authors study a quantum subsystem described by an effective non-Hermitian Hamiltonian derived from its exact frequency-dependent self-energy, and show that only complex-frequency fingerprinting can uniquely detect NHSE-induced responses, providing a rigorous framework for exploring non-Hermitian phenomena without approximation.

Decadal-scale observations reveal that plant diversity stabilizes ecosystem productivity over time. Phylogenetic diversity is the key driver of long-term stability, whereas plant height shapes short-term productivity dynamics.

Angiogenesis-targeting secretome therapies may provide a new therapy for ischemic heart disease. Here, the authors show that CCL28 promotes angiogenesis via CCR10 signaling, and recombinant CCL28 offers therapeutic potential in ischemic models, including diabetic conditions.

HIV infection is associated with increased risk of more severe Mpox, yet the underlying mechanisms aren’t well understood. Here, the authors reveal increased MPXV replication and immune dysfunction in SIV-MPXV co-infected rhesus macaques and, using proteomics and phosphoproteomics from multiple organs, identify involved pathways.

The ultrathin oxide nanosheets obtained through previous approaches usually exhibit amorphism or polycrystallinity, which limit their properties towards electronic devices. Here, the authors synthesize ultrathin antimony oxide single crystals with high dielectric constant (~100) and large breakdown voltage (~5.7 GV m⁻¹).

The authors analyze rare coding variants in 1990 individuals with congenital kidney anomalies, finding diagnostic variants in 14.1% of cases. They identify two new causal genes, ARID3A and NR6A1, along with 38 candidate genes, providing evidence for shared genetics with other developmental disorders.

Liu et al. developed a framework called ARNLE to explore host tropism of SARS-CoV-2 and found a shift from weak to strong primate tropism. Key mutations involved in this shift can be analysed to advance research on emerging viruses.

m6A modification has been reported to play roles in many developmental and pathological processes, but its role in AKI remains poorly understood. Here, the authors show the role and the mechanism of the m6A demethylase, ALKBH5 on IRI induced AKI.

In this study, the authors identify and characterize distinct Salmonella Typhimurium rough colony strains, likely originating from Chinese smooth colony strains around 1977 that predominantly belong to sublineage L6.5 and carry a specific csgD promoter mutation.

A microchip-based DNA synthesis method enables scalable production of complex DNA constructs.

Shigella sonnei is a major contributor to the global burden of dysenteric diarrhoea in developed countries. In this work, authors report a S. sonnei clone which has caused numerous waterborne shigellosis outbreaks in China from 2015 to 2020.

Mosses support carbon sequestration, nutrient cycling, organic matter decomposition and plant pathogen control in soils across the globe, according to a global survey of soil attributes in ecosystems with and without mosses.

Conversion electrodes with fast charging capability and extended lifespan remains challenging. Here, authors developed Cu_0.88Sn_0.02Sb_0.02Bi_0.02Mn_0.02S_0.9Se_0.1 with entropy-driven fast-charging capability as negative electrode for sodium-ion batteries, enabling fast charging up to 100 A g⁻¹.

Pancreatic ductal adenocarcinoma is a lethal human cancer with a poor 5-year overall survival rate. Here the authors perform an exome-wide analysis in a cohort of PDAC patients to identify three novel missense variants in PKN1, DOK2, and APOB genes, that are associated with PDAC risk.

Imaging sensitivity and quantitation in MRI can be enhanced via ratiometric MRI probes leveraging magnetic-susceptibility-dependent magnetic resonance tuning.

An abnormal stress memory effect is discovered in different types of glassy materials when they are subjected to a low strain after a high strain. This strategy can be used to depress the stress relaxation and increase the stability under loading.

All-perovskite triple-junction solar cell devices have been fabricated, with a certified efficiency of 23.3%; these devices retain 80% of their initial efficiency following 420 hours of operation.

Cellular metabolism is important in pluripotency and cell fate regulation. Here, authors observe chromatin remodeling followed by TCA enzyme translocation from the mitochondria to the nucleus, demonstrating pluripotency regulation by mitochondria to nucleus retrograde signaling.

RNA polymerase II (Pol II) transcription factories play a central role in gene expression and 3D chromatin organization. Here, the authors demonstrate that RUVBL2 directly regulates Pol II clustering at active gene promoters.

China is planning to launch its Tianwen-3 mission, with the purpose of bringing back a sample from Mars, by the end of the decade. This Perspective presents the scientific objectives and architecture of Tianwen-3, including a preliminary selection of landing sites and a description of the Mars Sample Laboratory that will curate the material on Earth.

Digital twins can be used to support planetary operations and analysis. Here, the authors show tri-aspect characterization of lunar far side regolith and investigate the origin of a fin-shaped rock via digital twin of Yutu-2 rover.

Fluorescence imaging and fluorescence recovery after photobleaching assays reveal that the mitochondrial nucleoid forms a suborganelle via liquid–liquid phase separation interactions between mitochondrial DNA and the mitochondrial transcriptional machinery.

Li–S chemistry can provide high-energy-density batteries. Here the authors use lithiated metallic phase 2D materials as a sulfur host for cathodes that leads to high-energy-density Li–S pouch cell batteries.

Alkaline polymer electrolyte fuel cells are promising power sources, but performance is limited by catalytic activity. Here the authors report a non-precious metal-based catalyst for electrocatalytic oxygen reduction that imparts outstanding fuel cell performance.

Catalytic asymmetric deuterations rely largely on two-electron reaction manifolds and are mostly limited to benzylic positions. Here, a metal-free platform using peptide- or sugar-derived chiral thiols and deuterium oxide allows for asymmetric open-shell deuteration at non-benzylic positions under visible-light irradiation.

Methods that analyse heterogeneity and compare tissue microenvironments using spatial omics data are challenging to develop. Here, the authors present SOTIP, a method that can perform spatial heterogeneity, spatial domain, and differential microenvironment analyses across multiple spatial omics modalities.

Restoring a protein's function in response to specific stimuli can enable a signalling pathway to be activated and the effect monitored over time. Here, a chemical rescue strategy for restoring protein function inside live cells is described, in which palladium catalysts are used to deprotect a propargylcarbamate group of a lysine analogue.

Surface-Enhanced Raman Scattering (SERS) integrated with optical waveguides enhances sensitivity, simplifies design for ultra-low analyte detection.

Exome-wide analyses identify low-frequency coding variants associated with esophageal squamous cell carcinoma. One of the risk variants, in CYP26B1, is associated with enhanced enzymatic activity and lower levels of all-trans retinoic acid in serum.

This study focuses on how endothelial cells contribute to ECM accumulation of renal fibrosis and suggests that MDK promotes ACTA2 expression by stabilizing the C/EBPβ protein.