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Authors realize simultaneous high thermoelectric performance and high plasticity in Mg-based semiconductors at room temperature, demonstrating their great potential for use in flexible thermoelectrics.

The authors employ zero-field muon spin relaxation to study time-reversal symmetry breaking (TRSB) in FeSe_1−xTe_x. For x = 0.64 with the highest superconducting transition temperature T_c = 14.5 K, which is known to host a topological surface state and Majorana zero modes within vortices, they find a TRSB superconducting state in the bulk.

J. Liu, C. Qu, Y. Liu and colleagues report an m⁷G-independent function of WDR4 in regulating translation machinery and cholesterol homeostasis in tumour-associated macrophages. They develop a targeting strategy using CpG-small interfering RNA to suppress tumour progression.

Human fibroblasts are reprogrammed to generate blastocyst-like structures called iBlastoids, which recapitulate aspects of embryo implantation.

The authors propose a targeted doping strategy that enables copper atoms to occupy specific positions within the material’s crystal structure, avoiding the unwanted defects typically introduced by conventional methods.

The authors form InSb nanoprecipitates in situ within the nanostructured MgAgSb matrix, serving as conductive channels that accelerate carrier transport, thereby enhancing carrier mobility and the power factor.

The authors identify two coexisting incommensurate charge density waves whose interplay leads to joint commensuration and a long-period moiré structure.

Astilbe chinensis is a perennial ornamental and medicinal plant in the Saxifragaceae family. Here, the authors report chromosome level genome assembly of this species and reveal the origin and evolution of a terpene biosynthetic gene cluster.

Magnetically doped topological insulators may exhibit exotic transport phenomena such as the quantum anomalous Hall effect, however the underlying mechanisms of ferromagnetic order are currently debated. Here, the authors reveal stabilized ferromagnetism in Cr-doped (Sb,Bi)₂Te₃ mediated by Te and Sb p-hole carriers.

The authors make an ionic thermoelectric cell with a eutectic solvent of formamide that can operate at temperatures as low as −35 °C by applying hydrophilic and gold coated treatments to the electrode and introducing a thermal separator.

A telomere-to-telomere genome assembly of allohexaploid bread wheat cv. Chinese Spring (CS-IAAS), along with transcriptomic and proteomic data, highlights wheat genome complexity and its structural and functional features.

Few-nanometre-thick flakes of trigonal and monoclinic Cr₅Te₈ can be grown using chemical vapour deposition, with the monoclinic phase exhibiting an anomalous Hall conductivity of 650 Ω^–1 cm^–1 and anomalous Hall angle of 5%.

Spin defects in 2D materials offer practical advantages for quantum sensing over their 3D counterparts. Here, the authors demonstrate quantum sensing under high pressure using boron vacancy centers in hBN placed inside a diamond anvil cell and use it to detect both stress gradient inside the pressure chamber and pressure-induced magnetic phase transitions.

Berry curvature connects to exotic electronic phases hence it provides important insights to understand quantum materials. Here, the authors report sign change of the anomalous Hall effect resulted from Berry curvature change at the interface of a topological insulator/magnetic topological insulator heterostructure.

Modifying the non-ribosomal peptide synthase (NRPS)/polyketide synthase (PKS) pathway to generate novel non-ribosomal peptides often results in a loss of productivity. Here the authors use evolutionary alignments of NRPS/PKS gene clusters to guide rational design of complexes that can produce novel lactones.

The transcription factor network required for primordial germ cell (PGC) specification is known to diverge in mammals. Here the authors show that hominidae-specific transposable element (TE) LTR5Hs becomes transcriptionally active during PGC specification, and LTR5Hs inactivation abrogates human PGC specification

Interwoven magnetic and non-magnetic layers in TbTi₃Bi₄ overcome kagome frustration, producing coupled elliptical-spiral magnetic and spin-density-wave orders and a very large anomalous Hall effect driven by strong electron–magnetic field interactions.

Machine learning is revolutionising materials modelling but requires high-quality training data. Here, the authors introduce autoplex, an open framework automating exploration and fitting of potential-energy surfaces across diverse materials.

Data retention ability and cycle numbers are the decisive properties of phase change materials in applications. Combining in-situ heating transmission electron microscopy techniques with ab-initial calculations, we investigated the phase transitions of binary Sb-Te compounds. The results revealed that Sb vacancies stabilize the cubic framework while the Te vacancies tend to destroy it. This distinguished difference originates from the distribution of antibonding electrons. Reducing Sb vacancies greatly raised the phase transition temperatures of both amorphous-cubic and cubichexagonal phases and therefore may improve the data retention ability and the cyclability of phase change materials.

Experimentally detectable signature of an axion insulator remains elusive. Here, the authors predict a topological phase diagram of MnBi₂Te₄/(Bi₂Te₃)_n heterostructure, where the chiral hinge mode induced by the surface anomalous Hall conductivity is identified as a signature of an axion insulator state.

Single-cell transcriptome profiling of human aneuploid blastocysts highlights global transcriptomic alteration and identifies novel dosage-sensitive genes in aneuploidy. Aneuploid embryos undergo unstable epiblast maturation caused by defects in the TGF-β and FGF pathways that impact trophectoderm progression.

The limited scalability of 1D semiconductors has restricted their large-area optoelectronic applications so far. Here, the authors report the low-temperature synthesis of wafer-scale van der Waals nanomeshes composed of self-welding Te nanowires on various substrates, showing improved transport and photoelectric properties.

The progression of oesophageal squamous cell carcinoma (ESCC) from early to advanced stages requires comprehensive molecular characterisation. Here, the authors perform a proteogenomics analysis of ESCC patient samples across nine histopathological stages and three phases, identifying key alterations and paths for progression.

First-principles calculations predict that Bi₂Se₃, Bi₂Te₃ and Sb₂Te₃ are topological insulators—three-dimensional semiconductors with unusual surface states generated by spin–orbit coupling—whose surface states are described by a single gapless Dirac cone. The calculations further predict that Bi₂Se₃ has a non-trivial energy gap larger than the energy scale k_BT at room temperature.

Current methods for detecting insertions from short read sequencing data generally have low sensitivity. Here, the authors develop a new tool that runs quickly and detects significantly more true positive insertions compared to any combination of existing methods.

Break-induced replication (BIR) repairs broken DNA but can also destabilize genomes. The authors identify 33 new genes controlling BIR completion, showing that spindle assembly and spindle positioning checkpoints coordinate repair, and that nuclear pore proteins regulate BIR at multiple steps.

How subgenome-divergent and -convergent transcription is mediated and harmonized in hexaploid common wheat genome remains unclear. Here, via characterizing the cistrome maps, the authors reveal that transposon elements with transcription factor binding ability have the potential to make the contribution.

Fc–IL-4, a typical type 2 cytokine, reinvigorates exhausted CD8⁺ T cells in tumours, underscoring this fusion protein as a potent immunotherapy that synergizes effectively with type 1 immunity against cancer.

Zhuang, Zi et al. identify cyclin-dependent kinase 3 (CDK3) as a driver of neuron loss in Alzheimer’s disease that is associated with brain atrophy and memory decline in mice. Inhibition of CDK3 (BMX330) is shown to limit neuronal loss and improve cognition.

The large-area growth of 2D transition metal dichalcogenides (TMDs) requires a precise control of metal and chalcogen precursors. Here, the authors implement a strategy using active chalcogen monomer supply to grow monolayer TMDs and their alloys, showing low defect density and improved optoelectronic properties.

The ferromagnetic transition in magnetic nanoparticles embedded in magnetic nanocomposite thermoelectric materials is attributed to the trapping and release of electrons, which increases the performance of the thermoelectric materials.

A RuO₂/glass metasurface with low temperature coefficient of resistance is proposed based on tunneling effect. The metasurfaces show ultra-robust broadband microwave absorption at extreme environments up to 1000 °C.

The dynamical axion quasiparticle, which is directly analogous to the hypothetical fundamental axion particle, is observed in two-dimensional MnBi₂Te₄, and has implications for quantum chromodynamics, cosmology and string theory.

Converting phenol in wastewater into valuable chemicals through electrochemical hydrogenation offers a sustainable route for resource recovery but lacks efficient catalysts. Here, the authors report a hierarchical Ru⁰/Ru^δ+/Al₂O₃ catalyst to achieve selective conversion of phenol to cyclohexanol.

The authors design a comfortable wearable thermoelectric generators system with high output power based on sandwiched thermoelectric model, fabricating wearable thermoelectric generators using Mg-based thermoelectric materials.

The authors present a PAM-PVP hydrogel ionic thermoelectric device using KI₃/KI and K₃Fe(CN)₆/K₄Fe(CN)₆ redox couples to harvest time-domain thermal energy without external charging, reaching 4% relative Carnot efficiency from 60 °C to 10 °C.

Flexible Ag₂Se possesses promising near-room-temperature thermoelectric performance, while trade-off in thermoelectric performance and flexibility enhances its practical utility. Here, the authors fabricate polycrystalline Ag₂Se-based thin film with a high ZT of 1.27 at 363 K by Te doping.

Hall resistance quantization measurements in the quantum anomalous Hall effect regime on a device based on the magnetic topological insulator V-doped (Bi,Sb)₂Te₃ show that the system can provide a zero external magnetic field quantum standard of resistance.

Chromosome-level genome assemblies of migratory and desert locusts, coupled with epigenomic profiling of migratory locusts, reveal chromatin dynamics underlying polyphenism and X-linked dosage compensation following autosomal gene translocation.

The symmetry, microscopy and spectroscopy signatures of altermagnetism are reviewed, and compared with traditional ferromagnetism and Néel antiferromagnetism, and magnetic phases with symmetry-protected compensated non-collinear spin orders.

A pioneering design strategy for amorphous p-type semiconductors can be used in high-performance, stable p-channel TFTs and complementary circuits, which may establish viable amorphous p-channel TFT technology and large-area complementary electronics in a low-cost manner.

Achieving room-temperature high anisotropic magnetoresistance ratios is highly desirable for magnetic sensors. Here, the authors observe a high anisotropic magnetoresistance ratio of −39% and a giant planar Hall effect (520 μΩ·cm) at room temperature under 9 T in β-Ag₂Te crystals grown by CVD.