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Showing 1–50 of 1060 results

Advanced filters: Author: Peter S Nelson Clear advanced filters

Reply to: a quantitative trait locus for reduced microglial APOE expression associates with reduced cerebral amyloid angiopathy

Lincoln M. P. Shade
Qi Qiao
David W. Fardo
Research26 Jan 2026
Nature Genetics

P: 1-2
Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990–2023: a Global Burden of Disease Study

Global Burden of Disease estimates show that between 1990 and 2023, the prevalence and burden of drug use disorders, inclusive of amphetamine, cannabis, cocaine and opioid use, have been increasing in high-income countries, particularly in the USA.

Jiseung Kang
Hyeon Jin Kim
Dong Keon Yon
Research16 Jan 2026
Nature Medicine

P: 1-18
Nanoscale ultrafast lattice modulation with a free-electron laser

Applications of optical laser-based techniques are limited by the long wavelengths of the lasers. Now, observations of phonons and thermal transport at nanometre length scales are reported with an all-hard X-ray transient-grating spectroscopy technique.

Haoyuan Li
Nan Wang
Diling Zhu
Research27 Jan 2026
Nature Physics

P: 1-6
Updated cost-effectiveness analysis of lung cancer screening for Australia, capturing differences in the health economic impact of NELSON and NLST outcomes

Silvia Behar Harpaz
Marianne F. Weber
Karen Canfell
ResearchOpen Access03 Nov 2022
British Journal of Cancer

Volume: 128, P: 91-101
National surveillance data analysis of COVID-19 vaccine uptake in England by women of reproductive age

Women of reproductive age may have specific concerns relating to perceived impacts on fertility and menstrual cycles that make them hesitant to receive COVID-19 vaccination. In this study, the authors explore COVID-19 vaccine uptake rates in women of reproductive age using linked data for ~13 million women in England.

Laura A. Magee
Erika Molteni
Sara White
ResearchOpen Access22 Feb 2023
Nature Communications

Volume: 14, P: 1-8
Caregiver acceptability, and uptake of voluntary medical circumcision among male children under 5 years in Gulu city, Northern Uganda

Donald Otika
Morrish Obol Okello
Felix Bongomin
ResearchOpen Access30 Jan 2026
Scientific Reports

P: 1-14
cellSTAAR: incorporating single-cell-sequencing-based functional data to boost power in rare variant association testing of noncoding regions

cellSTAAR advances noncoding rare variant association analysis by integrating single-cell genomics data.

Eric Van Buren
Yi Zhang
Xihong Lin
Research31 Dec 2025
Nature Methods

P: 1-12
Global, regional, and national burden of chronic respiratory diseases and impact of the COVID-19 pandemic, 1990–2023: a Global Burden of Disease study

Estimates from the Global Burden of Disease study reveal declines in chronic respiratory disease mortality between 1990 and 2023—especially during the COVID-19 pandemic—but the burdens on people affected remain substantial.

Jiyeon Oh
Soeun Kim
Dong Keon Yon
Research06 Jan 2026
Nature Medicine

Volume: 32, P: 197-223
Stability and progressive differentiation of T_FR cells are intrinsically and extrinsically controlled by T_FH programs

Here the authors perform longitudinal sampling of lymphoid organs along with fate mapping and matched single-cell RNA sequencing and TCR sequencing to define the developmental dynamics of follicular regulatory T (T_FR) cells. They find that T_FR cells undergo clonal expansion and progressive differentiation in a process that requires follicular helper T cells.

Jeong-Mi Lee
Paulo Lisboa Raeder
Peter T. Sage
ResearchOpen Access13 Jan 2026
Nature Immunology

P: 1-12
De novo and inherited dominant variants in U4 and U6 snRNA genes cause retinitis pigmentosa

De novo and inherited dominant variants in genes encoding U4 and U6 small nuclear RNAs are identified in individuals with retinitis pigmentosa. The variants cluster at nucleotide positions distinct from those implicated in neurodevelopmental disorders.

Mathieu Quinodoz
Kim Rodenburg
Carlo Rivolta
ResearchOpen Access09 Jan 2026
Nature Genetics

Volume: 58, P: 169-179
Polygenic prediction of body mass index and obesity through the life course and across ancestries

Polygenic scores for body mass index and obesity constructed using data from 5 million people with different ancestries were associated with distinct weight gain trajectories from early childhood to adulthood.

Roelof A. J. Smit
Kaitlin H. Wade
Ruth J. F. Loos
ResearchOpen Access21 Jul 2025
Nature Medicine

Volume: 31, P: 3151-3168
Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction

Multi-ancestry genome-wide and transcriptome-wide association studies of aortic stenosis identify more than 200 independent risk loci and provide insights into its genetic architecture.

Aeron M. Small
Ta-Yu Yang
George Thanassoulis
ResearchOpen Access19 Dec 2025
Nature Genetics

Volume: 58, P: 57-66
Minister set to reform Australia's universities

Peter Pockley
News31 Jan 2002
Nature

Volume: 415, P: 460
Nonsense suppressors of Saccharomyces cerevisiae can be generated by mutation of the tyrosine tRNA anticodon

Peter W. Piper
Marilyn Wasserstein
Fred Sherman
Research26 Aug 1976
Nature

Volume: 262, P: 757-761
Transitory Free Radicals in Irradiated Animal Tissues

PETER KENNY
BARRY COMMONER
Research20 Sept 1969
Nature

Volume: 223, P: 1229-1233
Neutralizing and binding antibodies are a correlate of risk of COVID-19 in the CoVPN 3008 study in people with HIV

Using data from the CoVPN 3008 study, the authors show that the neutralizing antibody correlate of risk holds in people living with HIV. However, the nAb correlate was weaker and shorter-lived in a vaccine-immunity versus hybrid-immunity population.

Nonhlanhla N. Mkhize
Bo Zhang
Peter B. Gilbert
ResearchOpen Access06 Oct 2025
Nature Communications

Volume: 16, P: 1-19
Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
Pathology and viral evolutionary dynamics in a hamster model of persistent SARS-CoV-2 infection

SARS-CoV-2 persistence in IL2rg-deficient hamsters shows sustained replication, tissue dissemination, and dynamic intra-host evolution, establishing a model to define mechanisms driving long-term infection and its effects.

Wanting Wei
Makoto Kuroda
Peter J. Halfmann
ResearchOpen Access08 Jan 2026
Communications Biology

P: 1-11
A saturated map of common genetic variants associated with human height

A large genome-wide association study of more than 5 million individuals reveals that 12,111 single-nucleotide polymorphisms account for nearly all the heritability of height attributable to common genetic variants.

Loïc Yengo
Sailaja Vedantam
Joel N. Hirschhorn
ResearchOpen Access12 Oct 2022
Nature

Volume: 610, P: 704-712
Open reading frames and translational control

MICHAEL KESSEL
PETER GRUSS
Research10 Mar 1988
Nature

Volume: 332, P: 117-118
Peak-Shift Technique in Gas-Liquid Chromatography : Trimethylsilyl Ether Derivatives of Alcohols

STANLEY H. LANGER
PETER PANTAGES
Research08 Jul 1961
Nature

Volume: 191, P: 141-142
The power of genetic diversity in genome-wide association studies of lipids

A genome-wide association meta-analysis study of blood lipid levels in roughly 1.6 million individuals demonstrates the gain of power attained when diverse ancestries are included to improve fine-mapping and polygenic score generation, with gains in locus discovery related to sample size.

Sarah E. Graham
Shoa L. Clarke
Cristen J. Willer
Research09 Dec 2021
Nature

Volume: 600, P: 675-679
C1q drives neural stem cell quiescence by regulating cell cycle and metabolism through BAI1

The authors uncover a direct, BAI1-dependent, role for C1q in the control of neural stem cell proliferation and quiescence via MDM2–p53 and p32, a complement cascade-independent mechanism of C1q action that has implications for central nervous system health and disease.

Katja M. Piltti
Anita Lakatos
Aileen J. Anderson
ResearchOpen Access11 Dec 2025
Nature Communications

Volume: 16, P: 1-18
Author Correction: The Solve-RD Solvathons as a pan-European interdisciplinary collaboration to diagnose patients with rare disease

Vicente A. Yépez
German Demidov
Holm Graessner
Amendments and Corrections06 Jan 2026
Nature Genetics

Volume: 58, P: 231
Genetic analyses across cardiovascular traits: leveraging genetic correlations to empower locus discovery and prediction in common cardiovascular diseases

Paloma Jordà
Yiwei Lai
Rafik Tadros
ResearchOpen Access29 Sept 2025
npj Genomic Medicine

Volume: 10, P: 1-22
Multi-omic profiling reveals age-related immune dynamics in healthy adults

This multi-omic longitudinal analysis of the healthy human peripheral immune system constructs the Human Immune Health Atlas and assembles data on immune cell composition and state changes with age, including responses to cytomegalovirus infection and influenza vaccination.

Qiuyu Gong
Mehul Sharma
Claire E. Gustafson
ResearchOpen Access29 Oct 2025
Nature

Volume: 648, P: 696-706
Reassessing the Lineage Fusion Hypothesis for the Origin of Double Membrane Bacteria

Kristen Swithers
Gregory Fournier
Pascal Lapierre
ResearchOpen Access18 Mar 2011
Nature Precedings

P: 1
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour

This genome-wide study of age at first sexual intercourse and first birth identifies 371 signals driven by reproductive biology, externalising behaviour and environmental effects, with later onset associated with lower incidence of some diseases.

Melinda C. Mills
Felix C. Tropf
Felix R. Day
Research01 Jul 2021
Nature Human Behaviour

Volume: 5, P: 1717-1730
Defining the role of common variation in the genomic and biological architecture of adult human height

Timothy Frayling, Joel Hirschhorn, Peter Visscher and colleagues report a meta-analysis of genome-wide association studies for adult height in 253,288 individuals. They identify 697 variants in 423 loci significantly associated with adult height and find that these variants cluster in pathways involved in growth and together explain one-fifth of the heritability for this trait.

Andrew R Wood
Tonu Esko
Timothy M Frayling
Research05 Oct 2014
Nature Genetics

Volume: 46, P: 1173-1186
Characterizing social behavior relevant for infectious disease transmission in four low- and middle-income countries, 2021-2023

Social contact data are important for modelling epidemic transmission dynamics but limited data are available for lower- and middle-income countries. Here, the authors present social contact data in Guatemala, India, Mozambique and Pakistan collected in 2021-2023.

Kristin N. Nelson
Moses C. Kiti
Saad B. Omer
ResearchOpen Access30 Oct 2025
Nature Communications

Volume: 16, P: 1-11
ProPE expands the prime editing window and enhances gene editing efficiency where prime editing is inefficient

Prime editing is a CRISPR methodology whose efficiency declines with distance from the target sequence. Here the authors demonstrate prime editing with prolonged editing window, proPE, which extends the editing distance, enabling the use of prime editing for therapeutic interventions.

Sarah Laura Krausz
Dorottya Anna Simon
Ervin Welker
ResearchOpen Access10 Oct 2025
Nature Catalysis

Volume: 8, P: 1100-1116
Erratum: Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion

William P Harris
Elahe A Mostaghel
Bruce Montgomery
Amendments and Corrections01 Mar 2009
Nature Reviews Urology

Volume: 6, P: 173
Election result leaves Australian scientists fearful over funding

Peter Pockley
News29 Nov 2001
Nature

Volume: 414, P: 478
Elucidating molecularly stratified single agent, and combination, therapeutic strategies targeting MCL1 for lethal prostate cancer

Despite improving therapeutic options, the prognosis for patients with metastatic castration-resistance prostate cancer (mCRPC) remains poor. Here, the authors identify MCL1 copy number alterations as a prognostic and predictive biomarker, demonstrating its therapeutic potential as a drug target, either alone or in combination, in patients with mCRPC.

Juan M. Jiménez-Vacas
Daniel Westaby
Adam Sharp
ResearchOpen Access08 Oct 2025
Nature Communications

Volume: 16, P: 1-22
Geographics and bacterial networks differently shape the acquired and latent global sewage resistomes

Antimicrobial resistance genes that have been mobilized between bacterial species represent a subset of the naturally occurring resistome. Here, the authors compare the abundance, diversity and geographical patterns of acquired resistance genes with latent resistance genes in global sewage metagenomes.

Hannah-Marie Martiny
Patrick Munk
Frank M. Aarestrup
ResearchOpen Access21 Nov 2025
Nature Communications

Volume: 16, P: 1-12
Carbon Monoxide Diffusing Capacity in Newborn Infants

Alfred N Krauss
David B Klain
Peter A M Auld
Research01 Sept 1976
Pediatric Research

Volume: 10, P: 771-776
Highly replicating hepatitis C virus variants emerge in immunosuppressed patients causing severe disease

Hepatitis C virus (HCV) variability and its phenotypic consequences aren’t well studied in relation to viral replication fitness and disease severity. Here, the authors identify a replication-enhancing domain in non-structural protein 5A, linking high replication fitness to severe disease outcomes, with implications for understanding HCV pathogenesis in immunocompromised patients.

Paul Rothhaar
Tomke Arand
Volker Lohmann
ResearchOpen Access07 Dec 2025
Nature Communications

Volume: 16, P: 1-18
Development of [¹⁸F]ACI-19626 as a first-in-class brain PET tracer for imaging TDP-43 pathology

High-affinity ligands were developed that specifically bind aggregated TDP-43, are selective over common co-pathologies, and possess pharmacokinetic profiles suitable for PET imaging to visualize TDP-43 pathology in the brains of patients.

Efthymia Vokali
Elodie Chevalier
Tamara Seredenina
ResearchOpen Access24 Oct 2025
Nature Communications

Volume: 16, P: 1-13
Efficient removal of Sr²⁺, V⁵⁺, and Rb⁺ ions from groundwater using a hybrid Mg-MCM-41/Talc composite; Siwa Oasis in Egypt as case study

Hussein A. ELsayed
Mohamed Hamdy Eid
Mostafa R. Abukhadra
ResearchOpen Access12 Jul 2025
Scientific Reports

Volume: 15, P: 1-22
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Calcium modified mesoporous silica from marble for the removal of cadmium, lead, chromium, iron, and manganese from Siwa Oasis groundwater

Mohamed Hamdy Eid
Attila Kovács
Mostafa R. Abukhadra
ResearchOpen Access25 Aug 2025
Scientific Reports

Volume: 15, P: 1-24
Inhibitory conformation of the reactive loop of α₁-antitrypsin

Peter R. Elliott
David A. Lomas
Jan Pieter Abrahams
Research01 Aug 1996
Nature Structural Biology

Volume: 3, P: 676-681
Isolation and characterisation of the φX174 ribosome binding sites

Jeffrey V. Ravetch
Peter Model
Hugh D. Robertson
Research24 Feb 1977
Nature

Volume: 265, P: 698-702
Pauling's model not universally accepted

PETER A. BANCEL
PAUL A. HEINEY
ALAN I. GOLDMAN
Research09 Jan 1986
Nature

Volume: 319, P: 104
Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits

Genome-wide association analysis in over one million individuals of European ancestry identifies 2,103 independent genetic signals (including 113 new loci) associated with blood pressure traits.

Jacob M. Keaton
Zoha Kamali
Helen R. Warren
ResearchOpen Access30 Apr 2024
Nature Genetics

Volume: 56, P: 778-791
Genome-scale CRISPR screens identify PTGES3 as a direct modulator of androgen receptor function in advanced prostate cancer

Genome-wide CRISPRi screens for modulators of androgen receptor (AR) protein levels using live-cell quantitative endogenous AR fluorescence reporters identify PTGES3 as a new regulator of AR stability and function in prostate cancer.

Haolong Li
James E. Melnyk
Felix Y. Feng
ResearchOpen Access05 Nov 2025
Nature Genetics

Volume: 57, P: 3027-3038
Serial Studies of Lung Volume and VA/Q in Hyaline Membrane Disease

Carlos A Tori
Alfred N Krauss
Peter A M Auld
Research01 Feb 1973
Pediatric Research

Volume: 7, P: 82-88
Marine isotope evolution

Peter D. Ward
Bruce K. Nelson
Kenneth G. MacLeod
Research30 Jul 1992
Nature

Volume: 358, P: 378
Skyrmion lattice domain formation in a non-flat energy landscape

Magnetic skyrmions are chiral spin structures that can form two-dimensional lattices. Here, the authors show how lattice domains grow under the influence of pinning effects in a non-flat energy landscape and that magnetic field oscillations help to stabilize order.

Raphael Gruber
Simon M. Fröhlich
Mathias Kläui
ResearchOpen Access19 Dec 2025
Communications Physics

Volume: 9, P: 1-8
SND1 binds to ERG and promotes tumor growth in genetic mouse models of prostate cancer

The ETS family transcription factor ERG is frequently overexpressed in prostate cancer and known to have a role in carcinogenesis, however, the underlying mechanism is less understood. Here, the authors report an interaction between ERG and SND1 as necessary for ERG-driven prostate cancer initiation using preclinical models.

Sheng-You Liao
Dmytro Rudoy
Valeri Vasioukhin
ResearchOpen Access16 Nov 2023
Nature Communications

Volume: 14, P: 1-16

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