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Showing 1–50 of 238 results

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Humoral IgG1 responses to tumor antigens underpin clinical outcomes in immune checkpoint blockade

Transcriptomic and clinical data analyses from multiple cohorts of patients with cancer receiving immunotherapy find that PD-1 blockade potentiates tumor-specific IgG1 plasma cell responses that complement cellular immunity and contribute to clinical benefit.

Edgar Gonzalez-Kozlova
Robert Sweeney
Sacha Gnjatic
ResearchOpen Access27 Jan 2026
Nature Medicine

P: 1-14
Global, regional, and national burden of chronic respiratory diseases and impact of the COVID-19 pandemic, 1990–2023: a Global Burden of Disease study

Estimates from the Global Burden of Disease study reveal declines in chronic respiratory disease mortality between 1990 and 2023—especially during the COVID-19 pandemic—but the burdens on people affected remain substantial.

Jiyeon Oh
Soeun Kim
Dong Keon Yon
Research06 Jan 2026
Nature Medicine

Volume: 32, P: 197-223
Activity of Aspartate Transcarbamylase in Heart and Liver of the Developing Rat

YVES NORDMANN
RUTH HURWITZ
NORMAN KRETCHMER
Research08 Feb 1964
Nature

Volume: 201, P: 616-617
The effects of α chain mutations cis and trans to the β6 mutation on the polymerization of sickle cell haemoglobin

Ruth E. Benesch
Suzanna Kwong
Reinhold Benesch
Research16 Sept 1982
Nature

Volume: 299, P: 231-234
Delay discounting correlates with depression but does not predict relapse after antidepressant discontinuation

Doron Elad
Giles W. Story
Quentin J. M. Huys
ResearchOpen Access08 Jan 2026
Molecular Psychiatry

P: 1-9
p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism

This study associates p53 loss and brain metastasis in breast cancer. Mechanistically, p53-null tumors recruit astrocytes that provide substrates for enhanced fatty acid synthesis via upregulated SCD1 expression, representing a targetable axis in the disease.

Kathrin Laue
Sabina Pozzi
Uri Ben-David
Research29 Dec 2025
Nature Genetics

Volume: 58, P: 116-131
Regulation of autosensitisation to encephalitogenic myelin basic protein by macrophage-associated and soluble antigen

LAWRENCE STEINMAN
IRUN R. COHEN
RUTH ARNON
Research01 Jan 1977
Nature

Volume: 265, P: 173-175
A stratified precision medicine trial targeting α_2A-adrenergic receptor agonism as a treatment for the cognitive biotype of depression

This study demonstrates that guanfacine immediate release enhances cognitive control circuit function and behavioral performance in a neurobiologically defined cognitive biotype of depression, achieving a 76.5% clinical response rate and improving life satisfaction, marking a promising advance in precision medicine.

Laura M. Hack
Jenna Jubeir
Leanne M. Williams
ResearchOpen Access13 Oct 2025
Nature Mental Health

Volume: 3, P: 1363-1373
Risk factors for mortality in patients with kidney failure on hemodialysis identified by proteomic analysis of CRIC and PACE studies

Patients with kidney failure undergoing maintenance hemodialysis have poor long-term survival. Here the authors use affinity-based proteomics to identify circulating risk factors for mortality in patients with kidney failure on hemodialysis.

Yue Ren
Mark R. Segal
Mark L. Unruh
ResearchOpen Access27 Nov 2025
Nature Communications

Volume: 16, P: 1-15
Psychological inoculation improves resilience to and reduces willingness to share vaccine misinformation

Ruth E. Appel
Jon Roozenbeek
Sander van der Linden
ResearchOpen Access18 Aug 2025
Scientific Reports

Volume: 15, P: 1-15
T-cell-mediated enhancement of host-versus-graft reactivity in mice fed a diet enriched in vitamin A acetate

Miroslav Malkovský
Andrew J. Edwards
Peter B. Medawar
Research24 Mar 1983
Nature

Volume: 302, P: 338-340
Rh Genes Allelomorphic to C

R. R. RACE
RUTH SANGER
SYLVIA D. LAWLER
Research28 Feb 1948
Nature

Volume: 161, P: 316
Pigments and Photosynthesis in a Carotenoid-Deficient Mutant Of chlamydomonas

RUTH SAGER
MARKO ZALOKAR
Research12 Jul 1958
Nature

Volume: 182, P: 98-100
In vitro and in vivo products of E. coli lactose permease gene are identical

Ruth Ehring
Konrad Beyreuther
Peter Overath
Research07 Feb 1980
Nature

Volume: 283, P: 537-540
KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease

The KL-VS haplotype of the Klotho gene has been associated with reduced risk of Alzheimer’s disease and dementia. Here the authors show an association between the KL-VS haplotype and amyloid-dependent tau accumulation using PET data.

Julia Neitzel
Nicolai Franzmeier
Michael Ewers
ResearchOpen Access22 Jun 2021
Nature Communications

Volume: 12, P: 1-12
A plasma proteomics-based candidate biomarker panel predictive of amyotrophic lateral sclerosis

Plasma proteomic analysis of presymptomatic individuals with amyotrophic lateral sclerosis identifies novel disease-associated proteins and enables the development of an accurate diagnostic biomarker panel.

Ruth Chia
Ruin Moaddel
Bryan J. Traynor
ResearchOpen Access19 Aug 2025
Nature Medicine

Volume: 31, P: 3440-3450
Cord Plasma Vasopressin, Erythropoietin, and Hypoxanthine as Indices of Asphyxia at Birth

Vineta Ruth
Frej Fyhrquist
Kari O Raivio
Research01 Oct 1988
Pediatric Research

Volume: 24, P: 490-494
Equivalence and Persistence of the Effects of Psychoactive Drugs and Past Experience

RUTH RUSHTON
HANNAH STEINBERG
MICHAL TOMKIEWICZ
Research30 Nov 1968
Nature

Volume: 220, P: 885-889
Intracellular Organic Phosphates as Regulators of Oxygen Release by Haemoglobin

REINHOLD BENESCH
RUTH E. BENESCH
Research15 Feb 1969
Nature

Volume: 221, P: 618-622
Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database

Here the authors provide an explanation for 95% of examined predicted loss of function variants found in disease-associated haploinsufficient genes in the Genome Aggregation Database (gnomAD), underscoring the power of the presented analysis to minimize false assignments of disease risk.

Sanna Gudmundsson
Moriel Singer-Berk
Anne O’Donnell-Luria
ResearchOpen Access31 Oct 2025
Nature Communications

Volume: 16, P: 1-14
Reduced cerebello-thalamo-cortical functional connectivity during traumatic memory retrieval in PTSD

This study uses whole-brain connectome analysis via functional MRI to investigate memory retrieval in individuals with post-traumatic stress disorder and its dissociative subtype, revealing distinct connectivity patterns and disruptions in subcortical–cortical integration during traumatic versus neutral memory processing.

Breanne E. Kearney
Maria Densmore
Ruth A. Lanius
Research12 Aug 2025
Nature Mental Health

Volume: 3, P: 1057-1069
The neural development of empathy is sensitive to caregiving and early trauma

People’s early experiences and dispositions influence their ability to show and feel empathy. Here, using a sample of children exposed to war-related trauma, the authors examine how parenting, temperament, anxiety, and adversity affect the maturation of neural responses associated with empathy.

Jonathan Levy
Abraham Goldstein
Ruth Feldman
ResearchOpen Access23 Apr 2019
Nature Communications

Volume: 10, P: 1-10
The neuronal chromatin landscape in brains from individuals with schizophrenia is linked to early fetal development

This study maps chromatin accessibility in neurons and glia in schizophrenia, revealing fetal-like regulatory patterns in adult neurons enriched for genetic risk variants, linking early brain development to schizophrenia pathogenesis

Kiran Girdhar
Jaroslav Bendl
Panos Roussos
Research27 Oct 2025
Nature Neuroscience

Volume: 28, P: 2451-2460
Intranasal cocaine self-administration in male mice

Animal models of drug use require specialized technical expertise and often differ from how humans consume drugs. Here, the authors establish a robust method which allows mice to self-administer intranasal cocaine, greatly improving face validity and ease of use.

Kirsty R. Erickson
Yizhen Quan
Cody A. Siciliano
ResearchOpen Access05 Dec 2025
Nature Communications

Volume: 16, P: 1-8
Insulin rapidly stimulates tyrosine phosphorylation of a M_r-185,000 protein in intact cells

Morris F. White
Ruth Maron
C. Ronald Kahn
Research14 Nov 1985
Nature

Volume: 318, P: 183-186
Immunomodulation of experimental allergic encephalomyelitis by antibodies to the antigen–Ia complex

Rina Aharoni
Dvora Teftelbaum
Joseph Puri
Research09 May 1991
Nature

Volume: 351, P: 147-150
Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization

Longitudinal proteomic profiling of over 1,800 patients revealed two distinct profiles of blood biomarkers measured on admission to hospital for COVID-19, which predict cognitive deficits 6 and 12 months later.

Maxime Taquet
Zuzanna Skorniewska
Paul J. Harrison
ResearchOpen Access31 Aug 2023
Nature Medicine

Volume: 29, P: 2498-2508
Mutation at H–2K locus influences susceptibility to autoimmune thyroiditis

RUTH MARON
IRUN R. COHEN
Research21 Jun 1979
Nature

Volume: 279, P: 715-716
Solar plages and the vorticity of the Earth's atmosphere

ROGER H. OLSON
WALTER ORR ROBERTS
E. RUTH HEDEMAN
Research13 Jul 1978
Nature

Volume: 274, P: 140-142
Autoantibodies to the insulin receptor in juvenile onset insulin-dependent diabetes

Ruth Maron
Dana Elias
Irun R. Cohen
Research30 Jun 1983
Nature

Volume: 303, P: 817-818
Strain tracking in complex microbiomes using synteny analysis reveals per-species modes of evolution

The evolution of microbial strains is revealed by analyzing structural variation.

Hagay Enav
Inbal Paz
Ruth E. Ley
ResearchOpen Access19 Jun 2024
Nature Biotechnology

Volume: 43, P: 773-783
Genomic investigations of unexplained acute hepatitis in children

An investigation using various methods reports an association between adeno-associated virus 2 and paediatric hepatitis of unknown aetiology.

Sofia Morfopoulou
Sarah Buddle
Judith Breuer
ResearchOpen Access30 Mar 2023
Nature

Volume: 617, P: 564-573
Interaction between Albumin, Lecithin and Cephalin

ERIC PONDER
RUTH V. PONDER
Research16 Apr 1960
Nature

Volume: 186, P: 235-236
Ependymomas produced after Intracerebral Inoculation of SV40 into New-born Hamsters

RUTH L. KIRSCHSTEIN
PAUL GERBER
Research21 Jul 1962
Nature

Volume: 195, P: 299-300
Excessive Thyrotropin Response to Thyrotropin-releasing Hormone in Pseudohypoparathyroidism

Edmond A Werder
Ruth Illig
Andreas Fanconi
Research01 Jan 1975
Pediatric Research

Volume: 9, P: 12-16
Treatment of multiple sclerosis with T–cell receptor peptides: Results of a double–blind pilot trial

Arthur A. Vandenbark
Yuan K. Chou
Dennis N. Bourdette
Research01 Oct 1996
Nature Medicine

Volume: 2, P: 1109-1115
A chiasma–hormonal hypothesis relating Down's syndrome and maternal age

PHILIP H. CROWLEY
DUSHYANT K. GULATI
RUTH DYER
Research01 Aug 1979
Nature

Volume: 280, P: 417-419
Prognostic value of polygenic risk scores for adults with psychosis

The inclusion of polygenic risk scores does not improve the performance of standard-of-care predictive models of disease outcomes in patients with psychosis.

Isotta Landi
Deepak A. Kaji
Alexander W. Charney
Research06 Sept 2021
Nature Medicine

Volume: 27, P: 1576-1581
Phylogenetic applications of whole Y-chromosome sequences and the Near Eastern origin of Ashkenazi Levites

Population genetics studies continue to debate whether Ashkenazi Levites originated in Europe or the Near East. Here, Rootsi et al.use whole Y-chromosome DNA sequences to unravel the phylogenetic origin of the Ashkenazi Levite and suggest an origin for the Levite founder lineage in the Near East.

Siiri Rootsi
Doron M. Behar
Peter A. Underhill
ResearchOpen Access17 Dec 2013
Nature Communications

Volume: 4, P: 1-9
Finger protein of novel structure encoded by hunchback, a second member of the gap class of Drosophila segmentation genes

Diethard Tautz
Ruth Lehmann
Herbert Jäckle
Research04 Jun 1987
Nature

Volume: 327, P: 383-389
A genetic linkage map of the laboratory rat, Rattus norvegicus

Howard J. Jacob
Donna M. Brown
Eric S. Lander
Research01 Jan 1995
Nature Genetics

Volume: 9, P: 63-69
Insoluble wild–type and protease–resistant mutant prion protein in brains of patients with inherited prion disease

Ruth Gabizon
Glenn Telling
Stanley B. Prusiner
Research01 Jan 1996
Nature Medicine

Volume: 2, P: 59-64
γ Interferon, CD8⁺ T cells and antibodies required for immunity to malaria sporozoites

Louis Schofield
Jaime Villaquiran
Victor Nussenzweig
Research23 Dec 1987
Nature

Volume: 330, P: 664-666
Effect of Fluorinated Pyrimidines on Herpes Simplex Virus

SIDNEY LERMAN
JOHN DOYLE
RUTH FRIEL DOYLE
Research09 Jun 1962
Nature

Volume: 194, P: 986-988
Cross-regulatory interactions among the gap genes of Drosophila

Herbert Jäckle
Diethard Tautz
Ruth Lehmann
Research18 Dec 1986
Nature

Volume: 324, P: 668-670
Liraglutide restores impaired associative learning in individuals with obesity

Hanssen et al. demonstrate that associative learning is reduced when metabolic sensing is impaired in obesity and can be restored by liraglutide.

Ruth Hanssen
Lionel Rigoux
Marc Tittgemeyer
ResearchOpen Access17 Aug 2023
Nature Metabolism

Volume: 5, P: 1352-1363
Large-scale functional hyperconnectivity patterns in trauma-related dissociation: an rs-fMRI study of PTSD and its dissociative subtype

The authors used region of interest (ROI)-to-ROI analysis to investigate functional connectivity patterns in patients with post-traumatic stress disorder (PTSD) and its dissociative subtype compared with healthy controls.

Saurabh B. Shaw
Braeden A. Terpou
Ruth A. Lanius
Research07 Sept 2023
Nature Mental Health

Volume: 1, P: 711-721
A publicly available deep learning model and dataset for segmentation of breast, fibroglandular tissue, and vessels in breast MRI

Christopher O. Lew
Majid Harouni
Maciej A. Mazurowski
ResearchOpen Access05 Mar 2024
Scientific Reports

Volume: 14, P: 1-10
Comprehensive characterization of protein–protein interactions perturbed by disease mutations

Human disease mutations affect protein–protein interfaces in a three-dimensional structurally resolved interaction network. Predicted oncoPPIs in cancer correlate with survival and drug sensitivity, and affect growth in vitro, supporting their relevance to disease pathogenesis.

Feixiong Cheng
Junfei Zhao
Joseph Loscalzo
Research08 Feb 2021
Nature Genetics

Volume: 53, P: 342-353
Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family

Quan Yi Li
Ruth A. Newbury-Ecob
J. David Brook
Research01 Jan 1997
Nature Genetics

Volume: 15, P: 21-29

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