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Polar molecule-based magnetic materials capable of multistate switching have garnered significant interest for their potential applications in next-generation memory devices, sensors, and energy conversion. Here the authors report a trinuclear cyanide-bridged FeCo compound that exhibits photo- and thermo-induced ferroelectric phase transition and solvent-switched on-off ferroelectricity.

Most kiwifruit species are vulnerable to high levels of heat stress. Here, the authors report natural variation at the GATA transcription factor binding site of EGY3 gene mediates chloroplastic ROS homeostasis to confer kiwifruit thermotolerance.

Tao, Feng, Yang, Liu et al. identify a lncRNA-dependent mechanism that controls ALKBH5-mediated demethylation and expression of ATF4, which confers an adaptive metabolic response under nutrient stress in cancer cells.

N input and warming alter plant traits and mycorrhizal communities, reducing belowground C inputs and stable soil organic C while accelerating decomposition, highlighting root–mycorrhizal interactions as key regulators of soil C under global change.

Chemoautotrophic carbon fixation is vital for evaluating permafrost carbon-climate feedback, but has been largely ignored. Here the authors find that dark carbon fixation predominates ~1/3 of the investigated thermokarst lakes on the Tibetan Plateau.

High-resolution 3D printing technology making use of two-photon polymerization instead of traditional machining is described, allowing low-cost and scalable production of large arrays of high-quality 3D Paul traps.

Although theoretical work has suggested the absence of an inversion temperature in aqueous solutions at infinite dilution conditions due to a lack of ion-ion interactions, this phenomenon remains underexplored. Here, the authors report phase-shifting interferometry visualisation experiments in alkali halide aqueous solutions and show that thermophobic behaviour becomes more dominant as the solution concentration decreases, and the disappearance of inversion temperatures in ultra-dilute solutions is corroborated by molecular dynamics modelling and an entropy model.

Thermodiffusive desalination is a water treatment method that does not rely on membranes. Here a multichannel device called a liquid Burgers cascade is shown to enhance performance for brine concentration and seawater desalination.

Liver transplantation can be an effective treatment for hepatocellular carcinoma, however, outcomes can be variable. Here, the authors use multi-omics to develop subgroups and identify a CAF-related classification.

SFTS is an emerging tick-borne disease with high mortality rates caused by the SFTS virus. Here, the authors identify LRP1 as an entry factor for SFTSV, show that SFTSV glycoprotein Gn interacts with LRP1 and that blocking LRP1 reduces viral infection and improves survival in lethal mouse models.

Difficulty swallowing after stroke and the neural circuitry underlying this is not fully understood. Here the authors demonstrate, using a mouse model, a potential neural circuit mechanism for effects of electroacupuncture on swallowing behaviour in post-stroke dysphagia.

The authors reveal that the Tibetan alpine permafrost region currently functions as a marginal CH₄ sink, and that future flux trajectories diverge under different emission scenarios as a result of the coupled effects of climate forcing and atmospheric CH₄ dynamics.

Crystallisation is influenced by various non-equilibrium factors such as thermal history, mechanical perturbations, and flow, however, the role of imposed mass fluxes on when crystallisation first becomes macroscopically observable remains underexplored. Here, the authors show experimentally that thermodiffusive and isothermal diffusive mass fluxes can cause aqueous potassium chloride to crystallise at lower local supersaturation ratios compared to spatially isothermal reference systems, highlighting the importance of spatially varying temperature and concentration fields for precise crystallisation control.

The pilot phase of PigGTEx, re-analyzing 5,457 published RNA-seq samples, presents a pan-tissue catalog of molecular quantitative trait loci. Cross-species comparisons identify traits with shared genetic regulation in humans.

The authors synthesize metal-organic cage crosslinked nanocomposites by incorporating self-assembled metal-organic cages with amino reaction sites into the polyetherimide matrix. The in-situ crosslinking achieves a homogeneous distribution of inorganic components, constructing robust organic-inorganic interfaces.

A haplotype-resolved genome of hybrid sugarcane cultivar XTT22 and population analyses of Saccharum accessions highlight the genome evolution of allopolyploids and provide opportunities for sugarcane breeding.

The International Brain Laboratory presents a brain-wide electrophysiological map obtained from pooling data from 12 laboratories that performed the same standardized perceptual decision-making task in mice.

Combined CRISPRi chemical genetics and comparative genomics reveal Mycobacterium tuberculosis drug resistance mechanisms and a potential opportunity to repurpose clarithromycin to treat tuberculosis due to inactivation of the whiB7 resistance factor in an entire Mtb sublineage.

Current desalination technologies are energy intensive and suffer from membrane degradation and fouling. Here, authors propose and explore the potential of thermodiffusion as a means of membrane-free, single-phase thermal desalination. A pathway towards a feasible thermodiffusive desalination is provided.

Cryo-electron microscopy structures of the human lysosomal transmembrane protein LYCHOS show that it comprises a transporter-like domain fused to a G-protein-coupled receptor, and that the transporter domain is similar to the plant PIN family.

Global soil carbon dynamics are regulated by the modification of soil organic matter (SOM) decomposition by plant carbon input (priming effect). Here, the authors collect soil data along a 2200 km grassland transect on the Tibetan Plateau and find that SOM stability is the major control on priming effect.

This study introduces a ChickenGTEx atlas of regulatory variants across 28 tissues and illustrates its utility in deciphering association signals for 39 complex traits in chickens.

Phosphoantigen-mediated BTN2A1 association drives BTN3A1 intracellular fluctuations outwards in a thermodynamically favourable manner, thereby enabling BTN3A1 to push off from the BTN2A1 ectodomain to initiate T cell receptor–mediated γδ T cell activation.

Permafrost stores large quantities of carbon (C), but uncertainty surrounds decomposability differences between active and permafrost layers. Here, Chen et al. use incubation experiments and a 3-pool model to find permafrost layers are equally or more labile, contributing to C vulnerability in Tibetan permafrost.

Two draft sequences of Gossypium hirsutum, the most widely cultivated cotton species, provide insights into genome structure, genome rearrangement, gene evolution and cotton fiber biology.

For reproduction, the human parasiteSchistosoma japonicumrelies on a complex and incompletely understood interplay between female and male schistosomes. Here the authors sequence the transcriptome of female and male schistosomes across eight time points during sexual development.

Soil nitrogen availability may alter carbon dynamics after permafrost thaw, but experimental evidence for this carbon-nitrogen interaction is still lacking. Here the authors show that elevated post-thaw nitrogen availability inhibits soil carbon release through its enhancement in microbial metabolic efficiency.