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Bistable superlattice switching between two lattice configurations with sharply contrasting periodicities has been observed in monolayer TaIrTe₄, a dual quantum spin Hall insulator.

2D polymer materials are often limited in performance by insufficient in-plane conjugation and poor charge transport. Guided by theoretical calculations, the authors present diketopyrrolopyrrole-based crystalline 2D poly(arylene vinylene)s with narrow optical band gaps of 1 eV and high charge carrier mobility.

Disentangling intertwined orders in quantum materials is challenging. Now, photoemission spectroscopy experiments show that magnetic fields can be used to disentangle such orders in a kagome superconductor.

The limited tunability of threshold voltage is a major obstacle for applying two-dimensional transistors in post-silicon electronics. Here, the authors show that bimetallic thiophosphates, such as LiInP₂S₆, enable programmable threshold voltages in both n-type and p-type 2D transistors, leading to low-power, high-speed complementary logic inverters.

Here, the authors reveal how twisting MoSe₂/WS₂ layers controls exciton behaviour. Combining theory and ultrafast spectroscopy, they show that lattice reconstruction creates distinct bright and long-lived excitons without hybridization effects.

The APOE-ε4 allele is the strongest genetic risk factor for late-onset Alzheimer’s disease, but it is not deterministic. Here, the authors show that common genetic variation changes how APOE-ε4 influences cognition.

Evo 2 is an artificial intelligence-based biological foundation model trained on 9 trillion DNA base pairs spanning all domains of life that predicts functional properties from genomic sequences and provides a rich generative model for researchers in biology.

An Fe^III/V redox mechanism in Li₄FeSbO₆ on delithiation without Fe^IV or oxygen formation with resistance to aging, high operating potential and low voltage hysteresis is demonstrated, with implications for Fe-based high-voltage applications.

Guided by density functional theory, a commercially viable refractory alloy is developed, which exhibits excellent room-temperature ductility and strength, and high strength at elevated temperatures.

A single-cell epigenomic atlas of human immune cells highlights cell-type-specific features associated with genetic or environmental exposures.

To address the phase instability issue of perovskites, ammonium propionic acid is introduced to enhance the phase stability of both perovskite layers in perovskite/perovskite/silicon triple-junction solar cells, resulting in improved efficiency and reproducibility.

Here the authors identify real-space contributions to the characteristics of high-harmonic generation in ReS2 and demonstrate the possibility of laser-controlled emission. They find that the spectrum is not just determined by the band structure, but also by the interference between HHG signals coming from different atoms within the unit cell.

Precise control of the growth of transition metal dichalcogenides layers in atomically thin van der Waals heterostructures has gained significant attention. Here, the authors report 100% overlapped vertical ReS₂/WS₂heterostructures by utilizing the twinned growth behaviour of two-dimensional materials.

Atomistic simulations are important for phase-change materials and devices. Here, the authors present fast and accurate machine-learned potentials, enabling full-cycle device-scale simulations and showcasing applications in studying memory and neuromorphic computing devices.

The origin of the nematic state in the kagome metal CsTi₃Bi₅ remains unclear. Here, using polarization-dependent angle-resolved photoelectron spectroscopy and ab initio based field theoretical methods, the authors propose a d-wave nematic order driven by electronic correlations via an orbital-selective mechanism.

A hybrid exciton is observed at the interface between an organic semiconductor and a transition metal dichalcogenide. This suggests engineering the exciton wavefunction can lead to efficient charge and energy transfer processes in such structures.

Vinyl acetate is an important polymer building block, but the mechanisms governing its catalytic production are not well understood. This study shows that dynamic palladium-acetate clusters determine catalyst efficiency and selectivity in vinyl acetate synthesis.

Dry reforming of methane (DRM) offers a promising route to convert greenhouse gases into valuable syngas, yet its industrial application is limited by catalyst deactivation and carbon deposition under severe conditions. Here, the authors introduce a Ce-modified, Ni-exsolved perovskite catalyst that exhibits synergistic effects, enabling highly efficient and durable DRM performance.

The authors develop a molecular dopant to avoid the dimerization of the electron-selective material phenyl-C₆₁-butyric acid methyl ester, resulting in enhanced stability and efficiency in inverted perovskite solar cells.

By encoding vectors and matrices at different frequencies within a single device, a device-aware neural network based on lithium niobate integrated nonlinear phononics can be created that can perform a four-class classification task with an accuracy of 98.2%.

Polygenic scores for body mass index and obesity constructed using data from 5 million people with different ancestries were associated with distinct weight gain trajectories from early childhood to adulthood.

Artificial molecules supported on templated surfaces attract enormous interest due to their tunable electronic properties. Here the authors use STM experiments and DFT calculations to show the formation of Pb artificial clusters on a IrTe₂ honeycomb template that are maximally stabilized by relativistic effects.

The theory-guided synthesis of a tungsten-based W₂TiC₂T_x MXene from a non-MAX nanolaminated ternary carbide (W,Ti)₄C_4−y is reported. The tungsten-rich basal plane of the W₂TiC₂T_x MXene is then examined for the electrocatalytic hydrogen evolution reaction using a combined experimental and theoretical approach.

Photonic memristor arrays fabricated from hexagonal boron nitride/silicon heterostructures provide a scalable, silicon-compatible solution for artificial vision systems, featuring broad spectral reconfigurability and promising performance characteristics.

This work challenges the view of nucleation governing halide perovskite grain morphology, showing that most additives act post-nucleation by boosting ion mobility across grain boundaries, triggering grain coarsening, similar to post-processing effects.

Metal gate electrodes with a high cohesive energy—platinum and tungsten—can be used to mitigate leakage currents and premature dielectric breakdown across chemical vapour deposition-grown multilayer hexagonal boron nitride, allowing the material to be used as a gate dielectric in two-dimensional-materials-based transistors.

Despite wide interest in human genome patents, there has been little information about exactly who owns what. Europe would do well to ponder over the stake already held by Japan and the United States.

Whole-genome sequencing data for 2,778 cancer samples from 2,658 unique donors across 38 cancer types is used to reconstruct the evolutionary history of cancer, revealing that driver mutations can precede diagnosis by several years to decades.

Analysis of cancer genome sequencing data has enabled the discovery of driver mutations. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium the authors present DriverPower, a software package that identifies coding and non-coding driver mutations within cancer whole genomes via consideration of mutational burden and functional impact evidence.

The oxidation of CO to CO₂ on rutile TiO₂ is a model reaction in heterogeneous catalysis, but the effect of substrate-specific oxygen activation timescales remains underexplored. Here, the authors monitor the reaction through time-resolved photoelectron spectroscopy at a free-electron laser and propose an O₂-TiO₂ charge transfer complex responsible for initiating the oxygen activation pathway for CO oxidation on rutile, showing that despite anatase being the more active photocatalyst, oxidation dynamics on rutile are faster.

Here, the authors examine the mechanisms behind cheatgrass’s successful invasion of North American ecosystems. Their genetic analyses and common garden experiments demonstrate that multiple introductions and migrations facilitated cheatgrass local adaptation.

Vapour-phase methods are promising for nanomaterial synthesis but the vaporization of different precursors for the synthesis of a broad nanomaterial space is challenging. Here electrified vapour deposition generates ultrahigh-temperature, high-flux atomic vapour at atmospheric pressure to rapidly vaporize diverse precursors, enabling the synthesis of multi-elemental nanomaterials with uniform compositions and tunable structures.

Large genome-wide meta-analysis of clinically diagnosed late-onset Alzheimer’s disease (LOAD) from 94,437 individuals identifies new LOAD risk loci and implicates Aβ formation, tau protein binding, immune response and lipid metabolism.

The authors present SVclone, a computational method for inferring the cancer cell fraction of structural variants from whole-genome sequencing data.