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Showing 1–50 of 76 results

Advanced filters: Author: Ziwen Liu Clear advanced filters

Exploring the potential effects of acute respiratory failure on patients with early-stage bronchopulmonary cancer

Ziwen Lv
Qi Feng
Dong Liu
ResearchOpen Access29 Dec 2025
Scientific Reports

Volume: 15, P: 1-10
A benchmark of expert-level academic questions to assess AI capabilities

Humanity’s Last Exam, a multi-modal benchmark at the frontier of human knowledge, is designed to be an expert-level closed-ended academic benchmark with broad subject coverage.

Long Phan
Alice Gatti
Davide Scaramuzza
ResearchOpen Access28 Jan 2026
Nature

Volume: 649, P: 1139-1146
Robust virtual staining of landmark organelles with Cytoland

Ziwen Liu et al. report Cytoland, an approach to train robust models to virtually stain landmark organelles of cells and address the generalization gap of current models. The training pipeline, models and datasets are shared under open-source permissive licences.

Ziwen Liu
Eduardo Hirata-Miyasaki
Shalin B. Mehta
ResearchOpen Access23 Jun 2025
Nature Machine Intelligence

Volume: 7, P: 901-915
Succinate-driven PKM2 succinylation and dimerization accelerates age-associated cardiac fibrosis

Elevated succinate in aging drives cardiac fibrosis by inducing PKM2 succinylation, dimerization, and nuclear translocation, activating fibroblasts. Targeting this axis may slow cardiac aging

Ziwen Wang
Ziyuan Zhang
Tingyi Sun
ResearchOpen Access10 Dec 2025
Communications Biology

P: 1-17
Remodelling bivalent chromatin is essential for mouse peri-implantation embryogenesis

Li, He, Liu and colleagues characterize the dynamic bivalent chromatin landscape during mouse peri-implantation development. They find that factor ZBTB17 works with KDM6A/B to resolve transiently maintained bivalent domains and prime gene activation.

Yanhe Li
Jincan He
Wenqiang Liu
Research01 Oct 2025
Nature Cell Biology

Volume: 27, P: 1797-1811
Transcriptome profiling of tumor-infiltrating lymphocyte-mediated cytotoxicity against patient-derived lung cancer organoids

A patient-derived organoid-TIL co-culture system delineates the clonal and molecular dynamics of effective anti-tumor immune responses in NSCLC.

Ziwen Qin
Hongchang Zhang
Chao Chen
ResearchOpen Access23 Nov 2025
Communications Biology

Volume: 8, P: 1-13
Bioengineered hybrid dual-targeting nanoparticles reprogram the tumour microenvironment for deep glioblastoma photodynamic therapy

The combination of photodynamic therapy and immunotherapy is emerging as a promising treatment for glioblastoma (GBM). Here this group encapsulates Fe3O4@BiFeO3 into bacterial outer membrane vesicles and M1 macrophage-derived exosomes hybrid membrane for synergistic photo-immunotherapy of GBM.

Rongrong Zhao
Ying Hou
Hao Xue
ResearchOpen Access18 Aug 2025
Nature Communications

Volume: 16, P: 1-22
Effect of high-dose N-acetylcysteine on exacerbations and lung function in patients with mild-to-moderate COPD: a double-blind, parallel group, multicentre randomised clinical trial

Evidence for the treatment of patients with mild-to-moderate COPD is limited. Here, the authors show that long-term treatment with high-dose N-acetylcysteine neither significantly reduced the annual rate of total exacerbations nor improve lung function in patients with mild-tomoderate COPD.

Yumin Zhou
Fan Wu
Li Chen
ResearchOpen Access30 Sept 2024
Nature Communications

Volume: 15, P: 1-11
Noncollinear harmonic spectroscopy reveals crossover of strong-field effects

The authors demonstrate non-collinear harmonic spectroscopy to observe the crossover of various strong-field effects on electron dynamics at femtosecond timescales. This provides insights into many-body effects at the carrier level and enables advancements in ultrafast optoelectronic and nanophotonics.

Jicai Zhang
Xiulan Liu
Tran Trung Luu
ResearchOpen Access18 Aug 2025
Nature Communications

Volume: 16, P: 1-8
Machine learning method based on radiomics help differentiate posterior pituitary tumors from pituitary neuroendocrine tumors and craniopharyngioma

Yukun Liu
Yanpeng Zhou
Siyuan Chen
ResearchOpen Access06 Jun 2025
Scientific Reports

Volume: 15, P: 1-8
Evolution of coastal forests based on a full set of mangrove genomes

Analysis of 48 newly generated genomes, including 32 mangrove species, sheds light on patterns of speciation and extinction of these woody, coastal plants.

Ziwen He
Xiao Feng
Suhua Shi
Research28 Apr 2022
Nature Ecology & Evolution

Volume: 6, P: 738-749
LPCAT1-mediated membrane phospholipid remodelling promotes ferroptosis evasion and tumour growth

Ziwen Li
Yameng Hu
Jun Li
Research26 Apr 2024
Nature Cell Biology

Volume: 26, P: 811-824
Photoisomerization-mediated tunable pore size in metal organic frameworks for U(VI)/V(V) selective separation

Selectively extracting U(VI) from seawater is challenging. Here, authors propose a dynamically matched spatial coordination strategy to improve the extraction of U(VI). With the size-matching and the spatial coordination, uranium species are precisely captured in confined coordination space.

Pengcheng Zhang
Yixin Zhang
Duoqiang Pan
ResearchOpen Access10 Mar 2025
Nature Communications

Volume: 16, P: 1-15
Proof-of-principle demonstration of muon production with an ultrashort high-intensity laser

Muons are conventionally produced from cosmic rays or with a proton accelerator. Now a proof-of-principle experiment demonstrates the feasibility of muon production with a laser-driven electron beam with gigaelectronvolt energy in a lead converter target.

Feng Zhang
Li Deng
Ruxin Li
Research06 May 2025
Nature Physics

Volume: 21, P: 1050-1056
Genomic evidence for rediploidization and adaptive evolution following the whole-genome triplication

Polyploidization-rediploidization process plays an important role in plant adaptive evolution. Here, the authors assemble the genomes of mangrove species Sonneratia alba and its inland relative Lagerstroemia speciosa, and reveal genomic evidence for rediploidization and adaptive evolution after the whole-genome triplication.

Xiao Feng
Qipian Chen
Ziwen He
ResearchOpen Access22 Feb 2024
Nature Communications

Volume: 15, P: 1-15
A mosquito salivary protein promotes flavivirus transmission by activation of autophagy

Mosquito saliva affects transmission of flaviviruses, but underlying mechanisms are incompletely understood. Here, the authors show that Aedes aegypti venom allergen-1 (AaVA-1) promotes dengue and Zika virus transmission by activating autophagy in host immune cells of the monocyte lineage.

Peng Sun
Kaixiao Nie
Gong Cheng
ResearchOpen Access14 Jan 2020
Nature Communications

Volume: 11, P: 1-15
Cordycepin prevents radiation ulcer by inhibiting cell senescence via NRF2 and AMPK in rodents

Radiation damage causes DNA foci to form and senescence, causing ulcers. Here, the authors show that a naturally occurring adenosine analogue, cordycepin, prevents cell senescence via an increase in AMPK/NRF2, so blocking ulcers caused by radiation on skin/intestine/tongue damage in rodents.

Ziwen Wang
Zelin Chen
Chunmeng Shi
ResearchOpen Access10 Jun 2019
Nature Communications

Volume: 10, P: 1-16
Comparison of artificial neural network-predicted PPG and HVPG with measured PPG in decompensated cirrhosis patients

Zhonghua Wang
Ziwen Liu
Jinhua Hu
ResearchOpen Access13 Oct 2025
Scientific Reports

Volume: 15, P: 1-14
Knowledge, attitude, and practice toward hypertrophic cardiomyopathy of patients with primary hypertension: a cross-sectional study

Gong Chen
Yannan Che
Mengnan Liu
ResearchOpen Access30 Aug 2025
Scientific Reports

Volume: 15, P: 1-12
Development of a LASSO dynamic prediction system for interbody cage subsidence following OLIF surgery

Jin Zhang
Hetong Li
Hongxun Sang
ResearchOpen Access13 Nov 2025
npj Digital Medicine

Volume: 8, P: 1-17
Research on the influential elements of user-centred digital art design for public space

Xu Jiang
Qiong Wu
Ziwen Jiang
ResearchOpen Access30 Apr 2025
Scientific Reports

Volume: 15, P: 1-20
Three-dimensional (3D) morphology of Sansha Yongle Blue Hole in the South China Sea revealed by underwater remotely operated vehicle

Tiegang Li
Aiping Feng
Yanru Wang
ResearchOpen Access20 Nov 2018
Scientific Reports

Volume: 8, P: 1-9
Therapeutic targeting nudix hydrolase 1 creates a MYC-driven metabolic vulnerability

MYC oncogene promotes tumourigenesis by coordinating cancer cell proliferation with metabolic adaptation to the consequent excessive oxidative stress. Here, the authors show that nudix hydrolase 1 (NUDT1) is a MYC-driven metabolic vulnerability and generate a NUDT1 protein degrader to treat preclinical MYC-associated cancer.

Minhui Ye
Yingzhe Fang
Guoliang Qing
ResearchOpen Access16 Mar 2024
Nature Communications

Volume: 15, P: 1-17
AMPK-regulated glycerol excretion maintains metabolic crosstalk between reductive and energetic stress

Zhai, Yang et al. report a central role for AMPK in regulating aldolase B-mediated glycerol synthesis and excretion under hypoxia as a mechanism to balance the trade-off between reductive and energy stress during tumour growth.

Xuewei Zhai
Ronghui Yang
Binghui Li
Research02 Jan 2025
Nature Cell Biology

Volume: 27, P: 141-153
Targeting androgen receptor phase separation to overcome antiandrogen resistance

Phase separation of androgen receptor underlies mutation-mediated antiandrogen resistance. A phenotypic screen enabled the discovery of ET516, which disrupts androgen receptor phase separation and effectively suppresses the growth of prostate cancer.

Jingjing Xie
Hao He
Guangya Zhu
Research13 Oct 2022
Nature Chemical Biology

Volume: 18, P: 1341-1350
Characterization of the genetic and clinical landscapes of DCTN1 gene in neurodegenerative diseases: a series of large case-control study

Xiaorong Hou
Xuxiong Tang
Lifang Lei
ResearchOpen Access21 Nov 2025
npj Genomic Medicine

Volume: 10, P: 1-8
PRMT inhibition induces a viral mimicry response in triple-negative breast cancer

Type I PRMT inhibition elicits potent antitumor activity associated with increased interferon response and intron-retained dsRNA accumulation, suggesting its potential combination with immune checkpoint inhibitors for cancer treatment.

Qin Wu
David Y. Nie
Cheryl H. Arrowsmith
ResearchOpen Access16 May 2022
Nature Chemical Biology

Volume: 18, P: 821-830
A fungal core effector exploits the OsPUX8B.2–OsCDC48-6 module to suppress plant immunity

Plant ubiquitin regulatory domain-containing proteins (PUX) play vital roles in CDC48-mediated protein quality control processes. Here Shi et al. show that a conserved core Magnaporthe oryzae effector (MoNLE1) can specially target the rice PUX protein OsPUX8B.2 and interfere with host immune responses.

Xuetao Shi
Xin Xie
Wende Liu
ResearchOpen Access22 Mar 2024
Nature Communications

Volume: 15, P: 1-17
Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages

Adipose tissue macrophages are central to controlling inflammation in the context of obesity. Here the authors present a new infrared dye (IR-61) that accumulates in the mitochondria of these cells resulting in anti-inflammatory effects that counter obesity-associated pathology in mice.

Yawei Wang
Binlin Tang
Chunmeng Shi
ResearchOpen Access04 Jan 2021
Nature Communications

Volume: 12, P: 1-16
Plasma cells are enriched in localized prostate cancer in Black men and are associated with improved outcomes

A recent report suggested Black men with prostate cancer were more responsive to immunotherapy. Here, the authors analysed prostate cancer gene expression profiles and show tumours from Black men and men with African ancestry have an increased proportion of plasma cells compared to those of White men and this correlates with improved outcome following treatment.

Adam B. Weiner
Thiago Vidotto
Edward M. Schaeffer
ResearchOpen Access10 Feb 2021
Nature Communications

Volume: 12, P: 1-10
Gut microbiome alterations in high-fat-diet-fed mice are associated with antibiotic tolerance

High-fat diet decreases antibiotic efficacy in a mouse model via an altered gut microbiota and decreased indole-3-acetic acid, which potentially converts tolerant bacterial cells into susceptible metabolically active cells.

Yuan Liu
Kangni Yang
Zhiqiang Wang
Research20 May 2021
Nature Microbiology

Volume: 6, P: 874-884
Modulation of nongenomic activation of PI3K signalling by tetramerization of N-terminally-cleaved RXRα

The transcription factor retinoid X receptor-alpha (RXRα) can also form homotetramers. Here the authors show that the anti-cancer agent K-80003 selectively inhibits the nongenomic action of N-terminally-cleaved RXRα in tumour cells by stabilizing its tetramerization but not that of full-length RXRα.

Liqun Chen
Alexander E. Aleshin
Xiao-kun Zhang
ResearchOpen Access17 Jul 2017
Nature Communications

Volume: 8, P: 1-14
An investigation of genetic diversity in three Dezhou donkey original breeding farms

Tianqi Wang
Ziwen Liu
Wenqiong Chai
ResearchOpen Access11 Jul 2023
Scientific Reports

Volume: 13, P: 1-8
Effects of pore size, water content, and oxygen-containing functional groups on oxygen adsorption in bituminous coal

Zhongjiu Ren
Dapeng Wang
Ziwen Liu
ResearchOpen Access26 Jun 2023
Scientific Reports

Volume: 13, P: 1-9
Analysis of the artificial vaginal microecology in patients after laparoscopic peritoneal vaginoplasty

Chenglu Qin
Guangnan Luo
Yujiang Fang
ResearchOpen Access11 Jun 2019
Scientific Reports

Volume: 9, P: 1-5
Reactive oxygen species generated from skeletal muscles are required for gecko tail regeneration

Qing Zhang
Yingjie Wang
Yongjun Wang
ResearchOpen Access08 Feb 2016
Scientific Reports

Volume: 6, P: 1-11
Molecular simulation of CO₂/N₂ injection on CH₄ adsorption and diffusion

Ziwen Li
Hongqing Hu
Hongjin Yu
ResearchOpen Access06 Sept 2024
Scientific Reports

Volume: 14, P: 1-15
A transcriptomic model for homologous recombination deficiency in prostate cancer

Adam B. Weiner
Yang Liu
Edward M. Schaeffer
Research05 Jul 2021
Prostate Cancer and Prostatic Diseases

Volume: 25, P: 659-665
An aptamer-drug conjugate for promising cancer therapy with comprehensive evaluation from rodents to non-human primates

Minhui Su
Yuan Liu
Weihong Tan
ResearchOpen Access24 Sept 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-17
Some new QEC MDS codes with large minimum distance

Lanqiang Li
Fuyin Tian
Li Liu
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-15
Long non-coding RNA DLEU1 predicts poor prognosis of gastric cancer and contributes to cell proliferation by epigenetically suppressing KLF2

Xiaobin Li
Zongze Li
Yimin Song
Research27 Dec 2017
Cancer Gene Therapy

Volume: 25, P: 58-67
MARCH8/NSUN6/ROS-mediated DNA damage positive feedback loop regulates cisplatin resistance in osteosarcoma

Mingyu He
Tao Li
Ye Yuan
Research19 Jul 2025
Cell Death & Differentiation

Volume: 32, P: 2412-2426
High-dose cytarabine with idarubicin consolidation for acute myeloid leukemia in first complete remission: a randomized controlled trial

Yu Zhang
Zinan Feng
Li Xuan
Research28 May 2025
Leukemia

Volume: 39, P: 1857-1864
Mapping gender patterns in “dynamic cultural spaces”: the case of Beijing’s open-air antiques “ghost market” at Panjiayuan

Guanliang Liu
Peiqing Cao
Mathew P. White
ResearchOpen Access19 Jul 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-16
Influence law of air flow and water immersion duration on the risk of secondary oxidation spontaneous combustion of coal

Ruirui Yu
Ziwen Dong
Zhenya Zhang
ResearchOpen Access02 Jan 2025
Scientific Reports

Volume: 15, P: 1-15
Aberrant brain network connectivity related to cognitive and emotional regulation in women with abdominal obesity

Qifu Li
Gaoyangzi Huang
Yi Lu
ResearchOpen Access10 Jul 2025
Scientific Reports

Volume: 15, P: 1-12
Metabolomics reveals the mechanism of Zhilong Huoxue Tongyu capsule in the treatment of heart failure

Li Chen
Dingshan Zhang
Mengnan Liu
ResearchOpen Access30 Apr 2025
Scientific Reports

Volume: 15, P: 1-13
Serum small extracellular vesicles-derived BST2 as a biomarker for papillary thyroid microcarcinoma promotes lymph node metastasis

Zhen Cao
Yuanyang Wang
Ziwen Liu
ResearchOpen Access18 Nov 2024
Cancer Gene Therapy

Volume: 32, P: 38-50
Dual-functional Cu₂O/g-C₃N₄ heterojunctions: a high-performance SERS sensor and photocatalytic self-cleaning system for water pollution detection and remediation

Shuo Yang
Kaiyue Li
Donglai Han
ResearchOpen Access20 Dec 2024
Microsystems & Nanoengineering

Volume: 10, P: 1-16
Nonlinear multi-head cross-attention network and programmable gradient information for gaze estimation

Yujie Li
Yuhang Hong
Benying Tan
ResearchOpen Access25 Jul 2025
Scientific Reports

Volume: 15, P: 1-14

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