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The transformations for aragonite precursors in coral are not fully understood but have implications in bio, biogenic and geological mineralization. Here, the authors use high-resolution mapping and observe exponential decay from the edge of four precursors to coral aragonite skeleton in Stylophora pistillata.

Optical spin orientation of itinerant ferromagnets in twisted MoTe₂ homobilayers is demonstrated, enabling control of topological Chern numbers with circularly polarized light.

Across 97% of forest area from eight million sampled forested locations worldwide, the density of aboveground biomass is lower near forest edges than in forest interiors. Given widespread forest fragmentation, this edge effect is estimated to be responsible for 9% reduction in forest aboveground biomass.

Experimental measurements of high-order out-of-time-order correlators on a superconducting quantum processor show that these correlators remain highly sensitive to the quantum many-body dynamics in quantum computers at long timescales.

This research identifies two neural factors linked to externalizing and internalizing symptoms through a longitudinal imaging-genetic cohort. Distinct neural configurations and cognitive-behavioral relevance highlight the need for tailored therapeutic strategies addressing psychiatric comorbidity across developmental stages.

Scanning nitrogen-vacancy microscopy unveils super-moiré spin textures emerging in twisted double-bilayer CrI₃ and provides real-space evidence of antiferromagnetic Néel-type skyrmions spanning multiple moiré cells.

Little is known about how edge states in topological materials interact with each other. Here, a quantum spin Hall insulator is used to show that when edge states are brought close together, additional gaps appear in the spectrum.

Guided by density functional theory, a commercially viable refractory alloy is developed, which exhibits excellent room-temperature ductility and strength, and high strength at elevated temperatures.

Predicting the function of enzymes remains difficult and current computational methods require improvement. Now EnzymeCAGE, a geometric deep learning model, has been developed to more accurately predict the functions of uncharacterized enzymes and reconstruct biosynthetic pathways.

The quantum anomalous Hall effect has so far been limited to temperature of the order of 20 mK. Here, Fijalkowski et al. report the existence of chiral edge channels up to the Curie temperature of bulk ferromagnetism of the magnetic topological insulator with a multi-terminal Corbino geometry.

Graphene nanostructures—like nanoribbons or quantum dots—hold great potential for applications. An extensive STM study elucidates how the details of the nanostructure edges heavily influence the electronic properties, which can vary between metallic and semiconducting according to the predominancy of zigzag or armchair edges.

A follow-up analysis of a clinical trial that evaluated anti-PD-1 therapy in patients with cancer who are living with HIV provides mechanistic insights into transcriptomic, cellular and cytokine changes related to immune checkpoint inhibitor treatment and identifies a signature associated with clinical response.

This paper uses multiomics to profile a large cohort of meningioma samples to highlight the role of the tumor microenvironment in driving the epigenetic changes underpinning tumor classification and prediction of outcome.

Song et al. report stochastic edge detection enabled by integrating memristor-based stochastic number encoders with logic gates to perform bitwise logic operations with statistical probabilities. A hardware Roberts cross operator achieves 95% less computational cost while withstands up to 50% bit-flip errors.

Quantum spin Hall edge states are protected by time-reversal symmetry and are expected to disappear in a strong magnetic field. Here, the authors use microwave impedance microscopy and find, surprisingly, edge conduction in mercury telluride quantum wells that survives up to 9 T with little change.

Functional studies of O-GlcNAcylation have often focused on individual modifications. Now, a systems-level approach has identified simultaneous O-GlcNAcylation events that coordinate cellular activities and tissue-specific functions.

The properties of electronic transport through edge states of three-dimensional quantum Hall-like states are not yet resolved. Now, increasing the surface area of the edges is shown to produce increased conductance, suggesting that chiral surface states are present.

Tokamak walls suffer erosion from steady and bursty heat loads. Here, the authors demonstrate that optimizing 3D magnetic field and cooling gas injection can tame destructive plasma bursts while enabling cooler, safer exhaust conditions.

Fracture behaviours in multilayer h-BN, involving interlayer-friction toughening and edge-reconstruction embrittlement, are identified through in situ experiments and theoretical analyses.

Warm Atlantic water circulates cyclonically around the Nordic Seas while gradually cooling. Here, the authors show that the retreat of the ice edge toward Greenland has led to further transformation of this water mass, which is no longer situated underneath sea ice when transiting the western Iceland Sea in winter.

The realization of cold and dense electron–hole systems by optical excitation is hindered by the heating caused by particle recombination. Now, cold and dense electron–hole systems have been observed in heterostructures with separated electron and hole layers.

Cue-evoked striatal dopamine release in mice encodes bidirectional trajectory errors, spatially and temporally separated from value coding, reflecting the relationship between the speed and direction of ongoing movement relative to optimal goal trajectories.

Charge-to-spin conversion is critical element for spintronic devices. In most materials, there are several sources of charge-to-spin conversion, which are often challenging to disentangle. Here, Chen et al succeed in disentangling spin Hall and Rashba-Edelstein contributions to charge-to-spin conversion in ultrathin MoTe2 using position dependent measurements of the current-induced spin accumulation.

Mucosal administration of a multivalent, adjuvanted vaccine against Clostridioides difficile promoted bacterial clearance and protected against morbidity, mortality, tissue damage and recurrence in mice.

Energy relaxation crucially impacts transport properties of mesoscopic devices. Here the authors show that energy can be distributed between distant parts of the sample, which may provide a resolution to an outstanding puzzle concerning energy conservation in transport through quantum Hall edges.

Vocal fold cancer tumours lose some of their malignant traits when mechanically stimulated by physiological stretch or vibrations, mimicking the opening and closing of vocal folds and phonation.

The relocalization of the vacuolar calcium pump Cdt1 to the plasma membrane contributes to fluconazole adaptation in Candida auris.

The quantum spin Hall state is predicted to consist of two oppositely polarized spin currents travelling in opposite directions around the edges of a topological insulator. Non-local measurements of the transport in HgTe quantum wells confirm the polarized nature of these edge states.

JWST imaged three of the gas giants orbiting the star HR 8799 to study their atmospheres. The uniform enrichment of heavy elements, including sulfur, indicates that they formed like Jupiter and Saturn by accreting a lot of icy and rocky solids.

Owing to electron localization, two-dimensional materials are not expected to be metallic at low temperatures, but a field-induced quantum metal phase emerges in NbSe₂, whose behaviour is consistent with the Bose-metal model.

Edge-localized plasma modes in a tokamak can damage its innermost wall. Simulations now show that fast ions can modify the spatio-temporal structure of these modes. These effects need to be considered in the optimization of control techniques.

The suppression of edge-localized modes in tokamak plasmas is crucial to prevent them from damaging the walls of the chamber. Now experiments confirm the role that magnetic islands play in suppressing these detrimental modes.

The quantum spin Hall effect disappears at high magnetic fields when the band inversion is lifted. The authors demonstrate that in contrast, in disordered samples, counter-propagating topological and quantum Hall edge channels prevent the detection of the trivial gap, explaining a previous observation.

Water-vapor interfaces have been studied with many techniques, yet open questions persist about their electronic and molecular structure. Here, the authors demonstrate the application of soft x-ray second harmonic generation to study the water surface by leveraging attosecond pulses at the LCLS and a flat liquid sheet microjet, providing insights on the H-bond structure.

Thermally assisted spin–orbit torque is used to switch the edge current chirality in mesoscopic quantum anomalous Hall devices.

An Fe^III/V redox mechanism in Li₄FeSbO₆ on delithiation without Fe^IV or oxygen formation with resistance to aging, high operating potential and low voltage hysteresis is demonstrated, with implications for Fe-based high-voltage applications.

WIN332 is an HIV-1 Env protein designed to elicit a new class of Asn332-glycan-independent antibodies (type II) to the V3-glycan site of Env. WIN332 immunization rapidly induces type-II V3-glycan antibodies with low inhibitory activity indicative of a neutralization activity in macaques.

The first melts generated in any solid-state mantle upwelling are kimberlitic CO₂-rich silicate melts that form at about 250 km depth through oxidation of elemental carbon to CO₂.

This study examines long-term changes in species richness across tropical forests in the Andes and Amazon. Hotter, drier and more seasonal forests in the eastern and southern Amazon are losing species, while Northern Andean forests are accumulating species, acting as a refuge for climate-displaced species.

Symmetry breaking is key to tissue formation. Now it is shown that symmetry breaking of epithelial spheroids is controlled by an interplay of collective migration with curvature and matrix remodelling.

Damaging energy bursts in a tokamak are a major obstacle to achieving stable high-fusion performance. Here, the authors demonstrate the use of adaptive and machine-learning control to optimize the 3D magnetic field to prevent edge bursts and maximize fusion performance in two different fusion devices, DIII-D and KSTAR.

The strength in BCC high-entropy alloys is associated with the type of mobile dislocations. Here the authors demonstrate by means of an ample array of experimental techniques that edge dislocations can control the strength of BCC high-entropy alloys.

JWST’s COSMOS-Web survey is used to create an ultra-high-detail dark matter map, revealing hidden filaments, clusters and distant structures. By tracing features out to z = 2, this map shows how dark and luminous matter build the cosmic web across cosmic time.

In the adrenal cortex, cholesterol used for steroid production is stored in lipid droplets. The authors demonstrate here the importance of the transcription factor HHEX in maintaining glucocorticoid levels and protecting lipid droplets from androgen-induced lipid depletion.