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Volume 47 Issue 1, January 2026

Cover story: Artificial intelligence is revolutionizing ion channel drug discovery by tackling the inherent complexity and therapeutic significance of these intricate membrane proteins. Advanced algorithms are now unlocking the elusive GluN1/GluN3A receptor, enabling efficient exploration of expansive chemical spaces despite limited structural and ligand data—ultimately uncovering promising new modulators with high precision. Doi: 10.1038/s41401-025-01710-8.

Volume 47 Issue 1

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