Clinical Sciences articles for United States of America (USA)

Time frame: 1 June 2025 - 30 May 2026

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Count: 3051

Article ‘Count’ for Clinical Sciences.

Journal Count Share
7 3.51
Mosaic Inverted Hemagglutinin Extracellular Vesicle Vaccines Elicit Protective Systemic and Mucosal Immunity against Heterosubtypic Influenza Infection 1.00
DNA Repair Enzyme Regulation Strategy for Enhanced Pancreatic Neuroendocrine Tumor Therapy via Targeting siRNA-Lipid Nanoparticles 0.07
Ultrasmall Surface-Charge-Modified Tantalum Oxide Nanoparticles for the Assessment of Articular Cartilage Using Contrast-Enhanced Computed Tomography 0.24
Single-Molecule and Super-Resolution Diffusion Quantification Unveils Reversible Enhancement of Lipid-Membrane Diffusivity by General Anesthetics 1.00
Cobalt-Doped Carbon Quantum Dots Work Synergistically with Weak Acetic Acid to Eliminate Antimicrobial-Resistant Bacterial Infections 0.13
Metal–Organic Framework-Remodeled Gut Microbiota Alleviates Colonic Inflammation via Selective Modulation of Roseburia intestinalis 0.07
Cell-Free Expression of Nipah Virus Transmembrane Proteins for Proteoliposome Vaccine Design 1.00
14 14.00
Charge-Engineered Microparticles for Targeted Delivery of RhoA Activator to Nucleus Pulposus 1.00
Hepatic adaptation to chronic metabolic stress primes tumorigenesis 1.00
Presentation of hemagglutinin on adjuvant-bearing self-assembling peptide nanofibers increases heterologous responses against influenza 1.00
Harnessing Albumin as a Carrier for the Delivery of Anti-HIV Drugs to the Lymphatic System 1.00
Mechanical and Structural Changes to the Annulus Fibrosus in Response to Sub-Failure Cyclic Loading 1.00
Chlorocatechol-Functionalized Gelatin Nanoparticles as a Hemostatic Agent with Antimicrobial Properties 1.00
Tear growth mechanisms in high-grade bursal-sided partial thickness tears in the rotator cuff measured with full volume magnetic resonance imaging methods 1.00
Equine Influenza Antigen-Based Particle Vaccine Protects Mice Against Homologous and Heterosubtypic Viral Challenges 1.00
Carboxybetaine zwitterionic coatings on kidney dialyzer components: Surface characterization and blood interactions 1.00
A noninvasive method for determining elastic parameters of valve tissue using physics-informed neural networks 1.00
Multiscale characterization of ultrasmall fluorescent core-shell silica nanoparticles in cartilage and synovial joints reveals rapid cartilage penetration and sustained joint residence 1.00
Large animal model of controlled peripheral artery calcification 1.00
Extracellular matrix repair and organization of chronic infected diabetic wounds treated with methacrylated chitosan-based hydrogels 1.00
A smart capsule with a bacteria- and pH-triggered enteric polymer coating for targeted colonic microbiome sampling 1.00
2 0.15
PH-Responsive Cu-Fe-MOF@Ag Nanocomposite Modulates Antibacterial and Anti-Inflammatory Activity in Infected Wounds 0.11
An MSR1‐Targeting Glycolipid Platform for Imaging the Changes of Phagocytic Macrophages in the Progression of Atherosclerotic Plaque 0.04
4 1.26
Circularly Polarized Metamaterial Cage for Homogeneous Signal‐to‐Noise Ratio Enhancement in Magnetic Resonance Imaging 1.00
Enzymatically Switchable Pyroptosis-Inducing Polymer Conjugate to Coordinate Host Immune Responses in Cancer Immunotherapy 0.12
LPS-Binding Hydrogel for TLR4-Mediated Microbiota-Immune Modulation 0.06
Bioinspired Smart Nanogels for Rapid Blue Laser‐Activated Hemostasis in Gastrointestinal Bleeding 0.08
20 12.75
Complementary plant protein pairing does not further increase post-exercise myofibrillar protein synthesis after a 20 g protein dose within a high-carbohydrate whole-food matrix in young adults: a randomized controlled trial 0.91
Assessing the Responsiveness of Musculoskeletal Tissues to Protein Supplementation in vivo in Older Adults: an Exploratory Randomized Controlled Trial 0.04
Effects of a one-year calcium-enriched permeate supplement on bone health in post-menopausal females: The RENEW randomized controlled intervention trial 0.09
Estimating proton density fat fraction using computed tomography attenuation in skeletal muscle and adipose tissue in a prospective clinical cohort 1.00
Diet-based weight-loss intervention is not associated with a meaningful change in lean soft tissue 1.00
Monitoring growth and body composition in children with 3-dimensional optical imaging: a pilot observational study 0.92
Independent effects of whey protein and alkali supplementation on muscle health in healthy older adults: factorial randomized controlled trial 1.00
Longitudinal micronutrient exposure reveals country-specific associations with risk of celiac disease in genetically susceptible children: the prospective TEDDY cohort 0.56
Differential associations between menstrual blood loss scores and iron status in Northern European and East Asian individuals: findings from a cross-sectional analysis of the iron genes in East Asians and Northern European adults (FeGenes) cohort 1.00
Ingestion of diverse protein-rich whole-foods result in similar post exercise whole body and myofibrillar protein synthesis rates compared with a more isolated protein source in young adults 0.25
Fiber Intake and Laxation in People With Normal Bowel Function: A Systematic Review 0.75
STRENGTHS AND LIMITATIONS OF URINARY SUGAR TESTING; AN OBSERVATIONAL STUDY OF INTESTINAL PERMEABILITY AND ABSORPTION IN ADULTS AND CHILDREN IN ZAMBIA AND TANZANIA WITH REFERENCE TO MUCOSAL BIOPSIES 0.05
Prenatal and preschool micronutrient supplementation and behavioral outcomes in school aged children in Nepal – a cohort study. 0.78
Lanthanum carbonate lowers serum phosphorus without altering body phosphorus burden in maintenance peritoneal dialysis patients: a randomized crossover trial 1.00
Arm circumference as a marker of muscle mass: cutoff values from NHANES 1999-2006 0.13
Relationship between skeletal muscle indicators and clinical outcomes in cystic fibrosis is modified by adiposity and CFTR modulator use: A cross-sectional analysis 1.00
Novel protein targets for type 2 diabetes prevention and their mediating role in the diet–disease relationship: evidence from 2 population-based cohorts and a Mendelian randomization analysis 0.06
Magnesium Treatment Increases Gut Microbiome Synthesizing Vitamin D and Inhibiting Colorectal Cancer: Results from a Double-Blind Precision-based Randomized Placebo-Controlled Trial 1.00
Associations of body mass index, waist circumference, and weight-adjusted waist index with body composition and biomarkers: A multinational pooled analysis 0.39
Empirical Dietary Index for Lower Urate Levels and Risk of Gout: Evidence From Cohort Studies 0.82
6 5.31
COVID-19 infection and risk of incident hypertension: a case-control time-to-event study 1.00
Longitudinal study of dietary intake and risk of persistent tinnitus in 2 large independent cohorts of women 1.00
Predicting first onset of suicide attempt among children with suicidal ideation or non-suicidal self-injury using machine learning: a prospective population-based cohort study 0.31
Lack of Relationship between Posttraumatic Stress Disorder and Coronary Atherosclerotic Burden among Twin Veterans from the Vietnam Era 1.00
A three-part model for the self-controlled case series design to estimate and characterize adverse event risk in an overlapping risk period after multiple vaccines: application to ischemic stroke following Pfizer-BioNTech bivalent COVID-19 vaccine and influenza vaccine 1.00
Mixture effects of prenatal exposure to polybrominated diphenyl ethers on urinary oxidative stress biomarkers in the Chemicals in Our Bodies cohort 1.00
22 19.81
MARRVEL-MCP: An agentic interface for Mendelian disease discovery via tool-augmented context engineering 1.00
Benchmarking genetic birth prevalence estimates against newborn screening data 1.00
Performance of LFSPRO prediction in TP53 mutation status for prospectively collected probands 1.00
Measuring disease likelihood in genomic ascertainment 1.00
Selective chr21 homolog silencing reveals polymorphisms influence the epigenetic silencing and functional dosage of RWDD2B 1.00
Newborn screening for type 1 diabetes using genome-based risk scores in the Early Check program 0.93
Identification of de novo variants from parent-proband duos via long-read sequencing 1.00
Low population penetrance of variants associated with inherited retinal degenerations 0.95
Residual allelic activity likely underlies the low rates of disease expression for predicted loss-of-function variants in population-scale biobanks 1.00
A scalable approach for genomic-first rare disorder detection in a healthcare-based population 1.00
Transcriptome-wide outlier approach identifies individuals with minor spliceopathies 1.00
Specifications of the ACMG/AMP variant curation guidelines for the analysis of germline PALB2 sequence variants 0.65
Single-cell analysis of human fibrous dysplasia bone reveals a fibrotic transcriptome and GNAS variants in endothelial, perivascular, and stromal cells 1.00
Phenome-wide association study of male and female sex chromosome trisomies in 1.5 million participants of MVP, FinnGen, and UK Biobank 0.78
When two plus four does not equal six: Combining computational and functional evidence to classify BRCA1 key domain missense substitutions 1.00
Extracting and calibrating evidence of variant pathogenicity from population biobank data 1.00
Exclusion-based exome sequencing in critically ill adults 18–40 years old has a 24% diagnostic rate and finds racial disparities in access to genetic testing 1.00
Exploring depression treatment response by using polygenic risk scoring across diverse populations 1.00
Genomic rare variant mechanisms for congenital cardiac laterality defect: A digenic model approach 1.00
Bi-allelic mutations in FASTKD5 are associated with cytochrome c oxidase deficiency and early- to late-onset Leigh syndrome 0.56
Consultation informs strategies for improving the use of functional evidence in variant classification 0.18
Insights on improving accessibility and usability of functional data to unlock their potential for variant interpretation 0.77
18 15.02
Associations Between Psychological and Trauma-Related Factors and Urinary Incontinence Severity and Treatment Response Among Women Veterans 1.00
Multi-dose Ibuprofen Prior to IUD insertion (MIPI): A Triple Blinded Randomized Controlled Trial 1.00
Does Contained Manual Morcellation in Minimally Invasive Hysterectomy Prevent Myometrial Cell Spillage? Evidence From Sequential Pelvic Washings. 1.00
Trachelectomy in decline: national trends, outcomes, and academic output across 3 major databases 0.36
Laparoscopic transabdominal cerclage: preconception versus postconception placement 1.00
Survival outcomes after inadvertent surgery in low-risk early-stage cervical cancer 0.82
Treatment of unfavorable bleeding patterns in contraceptive implant users with tranexamic acid: randomized clinical trial 1.00
Topical Therapy and Vulvar Malignancy Risk in Lichen Sclerosus: A Large Propensity-Matched Study 0.80
PGT-A Mosaicism Reporting Lacks Clinical Predictive Value For Live Birth in a Multisite, Double-Blinded Study with Independent Validation 0.38
Outcomes by Frailty and Mobility In Older Patients Undergoing Major Urogynecologic Surgery: A Planned Supplementary Study of the ASPIRe Trial 1.00
Vaginal hysterectomy versus laparoscopic hysterectomy for benign indications: complications and length of stay in a national analysis of contemporary data 0.71
Limits On Vaginal Intercourse after Mid-urEthral Sling (LOVE): A randomized trial 1.00
Semi-supervised deep learning for uterus and bladder segmentation on female pelvic floor MRI with limited labeled data 0.33
Impact of Social Determinants of Health on Fecal Incontinence Treatment In Older Women 1.00
Increased Frequency of Autism by Previous Diagnosis and Screening in Children with Fetal-Neonatal Alloimmune Thrombocytopenia (FNAIT) with and without an Intracranial Hemorrhage (ICH) 0.63
Recommended Standardized Terminology Related to the Clitoris and Vestibular Bulbs Based on a Structured Medical Literature Review. 1.00
Optimizing use of a uterine manipulator for laparoscopic hysterectomy: a cadaveric study of distances to the pelvic ureter 1.00
Association between urinary incontinence and device-measured physical activity: A cross-sectional study 1.00
19 17.13
Complement Anaphylatoxin Receptors C3aR1 and C5aR1 Are Dual Contributors of Chronic-Plus-Binge Induced Hepatic Inflammation and Injury 1.00
Dual Immune Lineage Activation Underlies Systemic Immunopathology in ACLF 1.00
Spatial Transcriptomics Profiling of Small Intestine Adenocarcinoma and Adenoma in Humans and a Murine Model with KRASG12D and Loss of CDKN2a-p16 1.00
Pseudogene-derived long non-coding RNAs GSM3P1/Gstm2-ps1 exacerbate sepsis-associated acute kidney injury by suppressing their parent gene translation 0.83
Quantitative 3D Imaging of Mouse and Human Intrahepatic Bile Ducts in Homeostasis and Liver Injury 1.00
Deficiency of Mesencephalic Astrocyte-derived Neurotrophic Factor Aggravates Acute Pancreatitis in Mice 1.00
Deletion of megalin in kidney tubular epithelium upregulates TGFβ1 signaling, aggravates ischemia/reperfusion kidney injury and accelerates the progression to CKD 0.94
Systemic Disease Progression and Neurodegeneration in the Gbe1 ys/ys Mouse Model of Glycogen Storage Disease IV 1.00
Selective Depletion of Gut Gram-Negative Bacteria Attenuates Alcohol-Binge-Induced Cardiovascular Dysfunction by Lowering Cardiac Anandamide Levels 1.00
Microglia promote neurodegeneration and hyperkatifeia during withdrawal and abstinence from binge alcohol. 1.00
Liver macrophage changes during early adaptation to alcohol exposure 0.91
Intra-host genomic variation of Haemophilus influenzae isolates from asymptomatic nasopharyngeal carriers involves genes encoding proteins with diverse inferred functions 0.44
Hepatocyte-specific MET deletion exacerbates acetaminophen-induced hepatotoxicity in mice 1.00
Stromal SRD5A2 promotes prostate growth through WNT5A-LEF1-IGF1 signaling in benign prostatic hyperplasia 0.92
Novel Perineural Pathways and The Dynamics of Simian Immunodeficiency Virus-Infected Macrophage Trafficking Out of the Central Nervous System 1.00
Peroxisome Proliferator-activated Receptor Agonist IVA337 Alleviates Inflammation and Fibrosis in MASH by Restoring Lipid Homeostasis 0.33
Chronic alcohol consumption enhances the differentiation capacity of hematopoietic stem and progenitor cells into osteoclast precursors. 1.00
Interleukin-6 Trans Signaling Regulates Neutrophilic Inflammation in Alcohol-Associated Hepatitis 0.75
Identification of pre-clinical biomarkers of MASLD vs MetALD and the impact of diet 1.00
20 13.78
Rocuronium dose and first-attempt intubation success in the critically ill: secondary analysis of two multicenter trials 1.00
Effects of an early restrictive versus liberal fluid strategy on long-term patient-centered outcomes in sepsis-induced hypotension (SHAMROC): an open-label, randomized controlled trial 0.75
Cost-Effectiveness of Community Tuberculosis Screening in South Africa 0.86
Lower Airway Dysbiosis in NTM+ Bronchiectasis is Associated with NET-Predominant Severe Phenotypes 0.88
Study of Risk Assessment Scores as Surrogate Endpoints in Pulmonary Arterial Hypertension Trials 0.86
Early mechanical reperfusion in high-risk pulmonary embolism supported by V-A ECMO: a multicenter international cohort study 0.02
Human Sputum Microbiome Composition and Sputum Inflammatory Cell Profiles Are Altered with Controlled Wood Smoke Exposure as a Model for Wildfire Smoke 1.00
Transmission of Bedaquiline-resistant Mycobacterium tuberculosis in KwaZulu-Natal, South Africa. 0.75
The Effectiveness of Isoniazid Preventive Treatment among Contacts of Multidrug-Resistant Tuberculosis: A Systematic Review and Individual-Participant Meta-Analysis. 0.30
Host-Microbe Multiomic Profiling Predicts Mortality in Sepsis. 1.00
Continuous On-Demand Diaphragm Neurostimulation to Prevent Diaphragm Inactivity During Mechanical Ventilation: A Phase 1 Clinical Trial (STIMULUS) 0.23
Telacebec, a Potent Agent in the Fight against Tuberculosis: Findings from a Randomized, Phase 2 Clinical Trial and Beyond 0.09
Anti-Anaerobic Antibiotics, Gut Microbiota, and Sepsis-associated Acute Kidney Injury. 1.00
Physiological Consequences of Breathing Effort According to the Mode of Ventilation During Acute Hypoxemic Respiratory Failure. 0.06
Dynamic 11C–Para–Aminobenzoic Acid Positron Emission Tomography/Computed Tomography for Visualizing Pulmonary Mycobacteroides abscessus Infections 1.00
Robotic versus Electromagnetic Bronchoscopy for Peripheral Pulmonary Lesions: A Randomized Trial (RELIANT). 1.00
Temporary Transvenous Diaphragm Neurostimulation for Weaning from Mechanical Ventilation (RESCUE-3). 0.57
Biologic Mechanisms Underlying the Heterogeneous Response to Tight Glycemic Control among Differentially Inflamed Patients in the HALF-PINT Trial. 1.00
Differences in Arterial Blood Gas Testing by Race and Sex across 161 U.S. Hospitals in Four Electronic Health Record Databases 0.96
Elastance May Determine the Neuromuscular Blockade Effect on Mortality in Acute Respiratory Distress Syndrome 0.44
14 12.53
Dual-Scale StaphAIR: Predictive Modeling for the Diagnosis of S. aureus Infection via Simultaneous Detection and Quantification of Cytokines and Antibodies 1.00
Rapid-Screening Differential Scanning Calorimetry for siRNA Duplex Thermal Analysis in Pharmaceutical Drug Development 1.00
Probing the Dynamic Pore Formation of Antimicrobial Peptide in Nanoscale Lipid Membranes 1.00
Rapid Antifungal Susceptibility Testing by Stimulated Raman Photothermal Imaging of D2O Metabolism 1.00
Lipidomics in Children: Noninvasive Sebum Sampling in Children and Adults Allows for Assessment of Lipidomic Differences According to Age, Sex, and Biological Relatedness 1.00
From Home to Transcriptome: Comparing the Transcriptomic Profile of Induced Immune Response via Lipopolysaccharide Stimulation in homeRNA and Venous Blood 0.88
Application of Analytical Measurement Uncertainty and Considerations toward Pharmaceutical Material Quality Control Strategies 0.91
Rapid Selective Detection of Phosphatidylethanols by Neutral Loss Scans in Tandem Mass Spectrometry to Evaluate Alcohol Consumption 1.00
ATR-FTIR Spectroscopy of Saliva and Machine Learning as a Screening Test for Sjögren Disease 0.54
Multiomics Analysis of Dried Plasma Spots Using Stable Isotope Internal Standards for Biomarker Discovery 1.00
Investigating Interfacial Interactions between the Adjuvant and Antigens in Pneumococcal Conjugate Vaccine In Situ at the Molecular Level 1.00
Tandem Bioluminescent Tests for Rapid Detection of Urinary Tract Infections and Antimicrobial Resistance Using a Portable Luminometer 1.00
Impact of Heat and Acidic Stress on the Biochemical Composition of Pseudomonas aeruginosa Bacteriophages─A Nanoscale AFM-IR Study 0.20
Rapid Multi-Omics for Bacterial Identification Using Flow Injection–Ion Mobility–Mass Spectrometry 1.00
35 23.83
Clinical Decision Support to Reduce Opioid Prescribing at Discharge for Inpatients Undergoing Surgery (LESS Study): An Interrupted Time Series Analysis. 1.00
Outflow Tract Patency and Ventricular Compression as Determinants of Cardiopulmonary Resuscitation Hemodynamics in a Transesophageal Echocardiography–guided Swine Model of Cardiac Arrest 1.00
Hydroxyethyl Starch and Perioperative Complications: A Systematic Review and Meta-analysis 0.27
Preoperative Olanzapine and Quality of Recovery after Ambulatory Surgery: A Randomized Clinical Trial. 1.00
Cryoneurolysis Thermal Graphs: In Vivo Descriptive Data from Ultrasound-Guided Percutaneous Thermocouples. 1.00
Intranasal naloxone reversal of opioid-induced respiratory depression in opioid-naïve individuals and self-reported daily opioid users. 0.26
Feasibility of a Multicomponent Protocol to Promote Dreaming during Surgical Anesthesia. 0.95
Perspectives of children, parents and health care providers on outcomes following anesthesia for surgery:: An international mixed methods stakeholder engagement study from the Pediatric Perioperative Outcomes Group. 0.28
Evaluating the Acute Effects of the Cannabinoid Dronabinol and the Opioid Hydromorphone Alone and in Combination: A Double-Blind, Randomized, Placebo-Controlled Trial in Knee Osteoarthritis. 1.00
Association of Peripheral Nerve Block with Postoperative Myocardial Injury in High-Risk Cardiac Older Adults Undergoing Hip Fracture Surgery: A Two-Center Retrospective Cohort Study. 0.05
Mechanical power and the association with postoperative impaired oxygenation and pulmonary complications in orthopedic patients: post hoc analysis of a cluster factorial randomized trial. 0.85
Evaluating The Statistical Robustness Of Randomized Controlled Trials Of Spinal Cord Stimulation For Pain Through The Use Of Fragility Index. 0.85
Changes in intraoperative rocuronium dosing following the introduction of sugammadex and association with postoperative respiratory complications: A retrospective cohort study. 0.85
Liposomal Bupivacaine, Plain Bupivacaine, and Saline for Transversus Abdominis Plane Blocks: The CLEVELAND Randomized Trial. 1.00
Discordances Between Preoperative Creatinine- and Cystatin C-Based Estimated Glomerular Filtration Rate and Outcomes After Noncardiac Surgery: An Observational Study. 0.07
Nitric Oxide to Reduce Acute Kidney Injury in Patients with Pre-existing Endothelial Dysfunction Requiring Prolonged Cardiopulmonary Bypass: A Randomized Clinical Trial. 0.95
Inpatient Cost of Complications After Total Hip and Knee Arthroplasty. 0.81
Paravertebral or serratus anterior plane block combined with PECS I (interpectoral) blocks versus paravertebral block for mastectomy: A cluster-randomized trial of 1507 patients. 1.00
Preoperative Hypnosis versus Mindfulness for Reducing Postoperative symptoms in Breast Surgery: A Randomized Clinical Trial. 0.29
Association of liver fibrosis FIB-4 score with perioperative complications and mortality: a retrospective multicenter analysis. 0.80
Pain as a driver of myocardial injury in hip fracture patients: a HIP fracture Accelerated surgical TreaTment And Care track (HIP ATTACK) Trial secondary analysis. 0.10
Mixed-Methods Analysis of Preoperative Distress and Postoperative Outcomes in a Prospective, Observational Cohort of Older Adults. 1.00
Revisiting infusion rate limitations for continuous lumbar plexus blocks in children and adolescents with 0.2% ropivacaine: a pharmacokinetic analysis. 1.00
Trends in Use of Medications for Opioid Use Disorder among Commercially Insured U.S. Surgical Patients, 2016-2022. 1.00
Bispectral Index-Guided Anesthesia for Older Patients Having Non-Cardiac Surgery: A Randomized Multicenter Trial. 0.03
Using Quantity of Service Data in Medicaid Claims to Estimate Anesthesia Time. 1.00
Heat Loss in Humans Warmed with Various Full-Body Forced-air Heating Systems. 0.60
Effect of urine-guided intraoperative hydration on incidence of acute kidney injury after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei: a randomized trial. 0.06
Fentanyl-induced ventilatory depression: population pharmacokinetic/ pharmacodynamic framework for evaluation of opioid-induced ventilatory depression. 0.05
A Randomized Controlled Trial of Intraoperative Ketamine for Acute Postsurgical Pain after Breast Cancer Surgery: The Moderating Effect of Baseline Temporal Summation of Pain. 1.00
Head Strikes Among Perioperative Personnel in the United States: A Mixed Methods Study. 1.00
Recovery of the acute hypoxic ventilatory response after reversal of a minimal neuromuscular block. A randomized, controlled trial in healthy, non-obese volunteers. 0.06
Increased Plasma Fibroblast Growth Factor 23 Significantly Associates with In-Hospital Acute Kidney Injury after Cardiac Surgery. 1.00
Analgesic benefits of motor-sparing fascial plane blocks in comparison to periarticular local infiltration analgesia for total hip arthroplasty: A network meta-analysis. 0.67
Clinical and Genetic Factors Associated with Intraoperative Minimum Alveolar Concentration Ratio: A Single-Center Retrospective Cohort and Genome-Wide Association Study. 1.00
7 3.55
Aggregation‐State Dynamics Drive Double Cooperativity Between Antimicrobial Peptides LL‐37 and HNP1 0.05
Positron Emission Tomography Imaging of Bacterial Infections With an Enterobactin Analog to Monitor Treatment Efficacy With a Catechol Antibiotic 1.00
Simultaneous Imaging of Cu+ and Cu2+ in Neural Cells Using DNAzyme Probes Reveals Mechanistic Link Between Copper Redox Imbalance and Amyloid Pathology 1.00
Rapid RASER MRI 0.25
Dissimilar Reactions and Enzymes for Psilocybin Biosynthesis in Inocybe and Psilocybe Mushrooms 0.13
Dynamic Photoacoustic Imaging of Mobile Cu(II) in Vivo via Catalytic Radical Cation Formation 0.13
Blood Retention and Kidney Clearance of Renal‐Clearable Gold Nanoparticles Strongly Correlate with Renal Injury Biomarkers 1.00
35 33.26
A Randomized Controlled Trial of a Digital Patient Decision Tool to Increase Sexually Transmitted Infection Testing in the Emergency Department 1.00
Extracorporeal Cardiopulmonary Resuscitation for Pediatric Out-of-Hospital Cardiac Arrest 0.13
Emergency Department Observation and Computed Tomography Use in Children With Blunt Abdominal Trauma 1.00
Improving Inferences Regarding Patient Events Using Emergency Medical Services Response-Based Data 1.00
Patterns of Intramuscular Chemical Sedation Use for Patients Receiving a Mental Health Consultation While in the Emergency Department 1.00
Early Clinical Deterioration Among Emergency Department Boarders: A Retrospective Analysis 1.00
Sex Differences in Clinical Outcomes and Resource Utilization Among Emergency Department Patients With Unexplained Syncope or Presyncope: A Prospective, Observational, Cohort Study 0.92
The National Pediatric Prehospital Readiness Project: First Comprehensive Assessment of United States Emergency Medical Services Agencies 1.00
Association Between Emergency Department Undertriage or Overtriage With Timeliness of Care and Patient Outcomes 1.00
A Randomized, Dose-Finding Study of Sphenopalatine Ganglion Block With Bupivacaine for Emergency Department Patients With Headache 1.00
Characterizing Emergency Department Visits to Pediatric Hospitals After Local Disaster Declarations 1.00
Capabilities Among Emergency Departments Participating in a Nationwide Quality Improvement Learning Collaborative to Care for Patients With Opioid Use Disorder: 2020 to 2024 1.00
Risk Factors for Pediatric Deep Neck Infection Revisit After Emergency Department Discharge for Pharyngitis or Localized Neck Symptoms 1.00
Cumulative Incidence of Stroke Disability and Mortality Following Emergency Department Discharge for Dizziness: A Cohort Study 1.00
Individual Survey Items in Emergency Department Patient Experience Surveys Have Limited Ability to Distinguish Unique Aspects of Care 1.00
Time to Vasopressor Initiation Is Not Associated With Increased Mortality in Patients With Septic Shock 1.00
Arterial Doppler Ultrasound Blood Flow Waveforms During Chest Compressions to Detect Arterial Line Pulsatility 1.00
Treatment of Opioid Use Disorder Across a National Emergency Department Practice Improvement Network 1.00
Serious Cardiac Outcomes and Physician Estimation of Risk in Emergency Department Patients With Presyncope Versus Syncope 0.91
Cool Running Water as a First Aid Treatment for Burn Injuries 0.44
Development of a Unified Geriatric Emergency Department Database, 2022 1.00
Clinical Pathway Revision Increases Amoxicillin Monotherapy and 5-Day Durations of Therapy for Pediatric Community-Acquired Pneumonia in the Emergency Department and Urgent Care: A Quality Improvement Initiative 1.00
Feasibility of Pediatric Diagnostic Quality Measurement in All United States Hospitals 1.00
Association Between Operator Experience and Procedural Outcomes of Tracheal Intubation in the Emergency Department and ICU 1.00
Outcomes Associated With an Age-Friendly Emergency Department Intervention 1.00
Not All Temperature Control Is Equal: High-Quality Temperature Control Is Associated With Improved Outcomes Following Out-of-Hospital Cardiac Arrest 1.00
Treatment Initiation and Outcomes Associated With Receipt of Emergency Department-Based Peer Support Following Opioid Overdose 1.00
Association of Two Preoxygenation Approaches With Hypoxemia During Tracheal Intubation: A Secondary Analysis 1.00
Usual Care for Low Back Pain at United States Emergency Departments, 2016-2022 1.00
Adoption of Boarding in Inpatient Hallways During Emergency Department Crowding 1.00
Psychedelic Trips: Travel Within the United States to Use Psychedelic Drugs After Legalization 1.00
Diagnostic Accuracy of Point-of-Care Ultrasound for Hip Effusion: A Multicenter Diagnostic Study 0.88
Emergency Department Ketamine Sedation: Frequency and Predictors of Critical and High-Risk Adverse Events 1.00
The Association Between Out-of-Hospital Drug-Assisted Airway Management Approach and Intubation First-Pass Success 1.00
Effect of Routine Opt-Out HIV Screening on Emergency Department Operational Metrics: Results From the Pragmatic Randomized HIV TESTED Trial 1.00
5 5.00
Budget Impact Analysis of the Balanced Opioid Initiative: A Cluster Randomized Trial Aimed at Deprescribing Opioids for Chronic Pain in Primary Care Settings. 1.00
Family Physician Workforce Trends: The Toll on Rural Communities 1.00
Measurement of Practice-Level Antibiotic Utilization in a Medicaid Patient-Centered Medical Home Program 1.00
Primary Care Patients With Opioid Use Disorder Symptoms: Initiation and Engagement in Treatment With Medicine 1.00
The Geographic Distribution of Family Physicians Providing Maternity Care and Opportunities for Expanding Access to Care in Rural Areas 1.00
22 15.35
Tirzepatide Versus Intensified Conventional Care After 2 Years of Treatment in Early Type 2 Diabetes : A Randomized Clinical Trial. 0.82
Multisite External Validation of a Clinical Screening Tool for Interpersonal Firearm Violence Risk. 1.00
The Effect of Fluvoxamine and Metformin for Fatigue in Patients With Long COVID : An Adaptive Randomized Trial. 0.21
Firearm Acquisition and New Exposure to Household Firearms After the Initial Pandemic Purchasing Surge: Results From the 2024 National Firearms Survey. 1.00
Sodium Correction Rates and Associated Outcomes Among Patients With Severe Hyponatremia : A Retrospective Cohort Study. 1.00
Effects of a Hospital-Based Violence Intervention Program on Community Violence in Boston, Massachusetts : A Target Trial Emulation. 1.00
Long-Term Mpox Sequelae 11 to 18 Months After Acute Illness : A Cohort Study in Two U.S. Cities. 1.00
Effect of Social Vulnerability on Efficacy of Bariatric Surgery Versus Medical and Lifestyle Intervention for Type 2 Diabetes: Analysis of the ARMMS-T2D Consortium of Randomized Trials. 1.00
Once-Weekly Oral Islatravir Plus Lenacapavir Versus Daily Oral Bictegravir, Emtricitabine, and Tenofovir Alafenamide in Persons With HIV-1 : A Phase 2 Randomized Study. 1.00
Integrating Methadone Services Into Primary Care in Ukraine: Two-Year Outcomes From a Randomized Trial. 0.71
Risk for Scrotal Surgery After Laparoscopic Donor Nephrectomy : A Population-Based Cohort Study. 0.16
Proteinuria or Albuminuria as Markers of Kidney and Cardiovascular Disease Risk : An Individual Patient-Level Meta-analysis. 0.44
Step Accumulation Patterns and Risk for Cardiovascular Events and Mortality Among Suboptimally Active Adults. 0.17
Effectiveness of Recombinant Herpes Zoster Vaccine in the U.S. Medicare Population, 2018 to 2019, by Immunocompetence and Prior Receipt of Live Zoster Vaccine. 1.00
Association Between Body Composition and Cardiometabolic Outcomes : A Prospective Cohort Study. 0.31
The Potential Impact of Ending the Ryan White HIV/AIDS Program on HIV Incidence: A Simulation Study in 31 U.S. Cities. 1.00
Treatment With Canagliflozin Versus Placebo in Children and Adolescents With Type 2 Diabetes : A Randomized Clinical Trial. 0.83
Efficacy of a Very-Low-Calorie Weight Loss Diet Plus Exercise Compared With Exercise Alone on Hip Osteoarthritis Pain : A Randomized Controlled Trial. 0.08
Evaluation of a Region-Wide Hospital-Based Violence Intervention Program : A Pilot Cohort Study. 1.00
Medications and Risk for Microscopic Colitis: A Nationwide Study of Older Adults in Sweden. 0.50
Birth Cohort Effects in Appendiceal Adenocarcinoma Incidence Across the United States. 1.00
Effects of a Hypotension-Avoidance Versus a Hypertension-Avoidance Strategy on Neurocognitive Outcomes After Noncardiac Surgery. 0.11
17 10.20
Continuous Versus Short EEG After Ischemic Stroke: What cEEG Adds for Detecting Abnormalities and Predicting Post-Stroke Epilepsy 0.26
Use of Machine Learning to Identify Markers of Risk for Fragile X‐Associated Tremor/Ataxia Syndrome: A Preliminary Analysis 1.00
Longitudinal Phenotypic Trajectories in GNAO1-Related Disorders: Defining Disease Progression and Clinical Profiles 0.17
Homozygous RFC1 AAGGG Repeat Expansions Are Common in Idiopathic Peripheral Neuropathy 1.00
Enhanced Sensitivity of a Modified Quaking‐Induced Conversion Diagnostic Test for the Broad Detection of Sporadic and Inherited Prion Diseases: A Retrospective Study 0.07
Topographical Variation of Iron‐Rimmed Lesions in the Multiple Sclerosis Brain and Spinal Cord: A Neuropathological Study 0.18
Intranasal Seletracetam in a Patient with Reading Epilepsy: First‐in‐Human Use to Prevent Reflex Seizures 0.20
The Phenotypic Spectrum of Sporadic Creutzfeldt‐Jakob Disease Cortical Subtype 0.18
Association between Human Leukocyte Antigen Alleles and Neuropathological Outcomes in Lewy Body Disease 0.97
A Digital Measure of Eye Movements During Reading Sensitively Captures Oculomotor and Speech Dysfunction, Early Changes, and Disease Progression in Ataxias 1.00
Longitudinal Analysis of Neuroradiological Biomarkers for Fragile X‐Associated Tremor/Ataxia Syndrome and Implications for Clinical Trials 1.00
The Spectrum of Neurologic Phenotypes Associated With scpiNUS1/i/scp Pathogenic Variants: A Comprehensive Case Series 0.29
Midlife Steroid‐Binding Globulin Levels and iIn Vivo/i Neuroimaging Measures of Tau in Older Men and Women 0.93
Biallelic Variants in the scpiDARS2/i/scp Gene as a Novel Cause of Axonal Charcot–Marie–Tooth Disease 0.04
Proteomics and the Risk of Incident Embolic and Thrombotic Stroke 1.00
Volumetric scpMRI/scp Comparing Longitudinal Change in scpMOGAD/scp to scpNMOSD/scp, scpMS/scp and Healthy Controls, and Disability Associations 1.00
Clinical, Prognostic, and Longitudinal Functional and Neuropsychological Features of West Nile Virus Neuroinvasive Disease in the United States: A Systematic Review and Meta‐Analysis 0.91
33 31.09
Intraoperative Vasopressor Administration and Anastomotic Leak following Elective Colorectal Resection in the Era of Goal Directed Hemodynamic Therapy 1.00
A Prospective, Randomized, Multicenter Trial Comparing Lactated Ringer's Alone or With 5% Albumin for Resuscitation of Large Burns The Acute Burn ResUscitation Multicenter Prospective Trial 2 (ABRUPT2). 0.88
Comparative Effectiveness of Single Versus Bilateral Lung Transplantation in Dually Listed Recipients: A National Target Trial. 1.00
A Multicenter Randomized Controlled Trial on the Surgery of Fractured Ribs: The SOFRIB Trial. 0.80
Preoperative GLP-1 Receptor Agonist Use and Weight Loss Outcomes Following Bariatric Surgery. 1.00
Long Term and Oncologic Outcomes for Patients Receiving Piperacillin-Tazobactam or Cefoxitin as Antibiotic Prophylaxis for Pancreatoduodenectomy. 1.00
Long-term Outcomes of Biologic versus Synthetic Mesh for Parastomal Hernia Repair: Post-Hoc Analysis of a Multicenter Randomized Clinical Trial. 1.00
Practice, Policy, and Research Recommendations to Improve Decision-Making about Surgery for People Living with Dementia: A Delphi Panel Consensus. 1.00
Impact of Normothermic Regional Perfusion on Clinical Outcomes in Kidney Transplantation from Donors After Circulatory Death: A US Nationwide Analysis of 38,048 Cases. 1.00
Sensitivity of Insurance Claims Codes in Identifying Robotic Assisted Surgery. 1.00
A Phase III Randomized Controlled Trial of Pyloroplasty versus No Pyloroplasty in Patients Undergoing Minimally Invasive Esophagectomy or Robot-Assisted Minimally Invasive Esophagectomy. 1.00
Rare and Tricky: The Relationship Between Hospital Trauma Volume and Delay in Surgical Intervention in Blunt Intestinal Injury. 1.00
Postoperative Pancreatic Fistula After Pancreatoduodenectomy: Can Radiomics Improve Clinical Risk Scores? 1.00
A Randomized, Single-Center, Superiority Trial of Radioactive Seed Localization Versus Wire Localization for Malignant Breast Disease 1.00
Cryoanalgesia Increases Neuropathic Pain in Adults Undergoing Minimally Invasive Surgery: A 1-Year Follow-up of a Randomized Study. 1.00
A Multicenter Double-blind Randomized Sham-controlled Trial Assessing the EndoBarrier Duodenal-jejunal Bypass Liner for the Treatment of Poorly Controlled type 2 Diabetes Mellitus with Concomitant Obesity: The ENDO Trial. 1.00
Prescription Default Nudges for Opioid Reduction after Major Surgery (NORMS): A Randomized Controlled Trial. 1.00
Comparative Safety of Robotic Versus Laparoscopic Bariatric Surgery. 1.00
Upfront Colectomy vs. Initial Appendectomy followed by Completion Colectomy for Appendiceal Cancer: A Comparison of Outcomes. 1.00
Association of Prophylactic Antibiotic Guideline Non-Adherence with Surgical Site Infections in Patients Receiving Perioperative Vancomycin: Results from a Multi-Institutional Combined NSQIP and MPOG Registry. 1.00
U.S. Surgical Practice: 23-Year Trends in Medicare Procedures and Reimbursement. 1.00
Mesh-related Outcomes of Biologic versus Synthetic Mesh for Single-stage Repair of Contaminated Ventral Hernias: A Five to Ten Year Analysis of a Randomized Controlled Trial. 1.00
Postoperative Opioid Prescribing Among Adults with Disabilities After a Medicare Opioid Limit Policy. 1.00
Long-Term Outcomes of Patients Undergoing Two-Stage Hepatectomy For Extensive Colorectal Liver Metastasis Treated With Perioperative Hepatic Artery and Systemic Chemotherapy. 0.95
Treatment Trends and Outcomes of Endovascular versus Open Thoracoabdominal Aortic Aneurysm Repair - A Single-center Comparative Cohort Study. 1.00
Defining Global Benchmarks for Robotic Liver Resections: An International Multicenter Study. 0.08
Ex-situ Split Transplants into Adult Recipients can Provide Long-term Outcomes Equivalent to the Gold Standard Splits from Living Donors 0.80
Stratifying Endoscopic Submucosal Dissection Risks: A Validated Perforation Preoperative Risk Scoring Tool. 1.00
Mosaic Loss of Y Chromosome Defines a Proximal Tubular Cell State Associated with Recovery from DGF and of Allograft Quality and Functional Reserve Post DCD Kidney Transplantation. 0.96
Preoperative Electrodiagnosis of Brachial Plexopathy is Associated With Diminished Functional Outcomes After Surgery for Neurogenic Thoracic Outlet Syndrome. 1.00
Prophylactic Antibiotic use and Outcomes in Infants Undergoing Pyloromyotomy: A Multicenter Propensity Matched Cohort Analysis. 1.00
The Death of Laparoscopy - Volume 2: A Revised Prognosis. A retrospective study. 0.63
Implementation of a Contrast Challenge Algorithm for Adhesive Small Bowel Obstructions in Children: A Prospective, Multi-Institutional Study. 1.00
41 20.11
Effect of apremilast on whole-body magnetic resonance imaging of peripheral and axial inflammation in patients with psoriatic arthritis 0.64
Thresholds for efficacy outcomes in psoriatic arthritis vary according to baseline disease activity but not according to prior tumour necrosis factor inhibitor treatment 0.50
Anti-PAD4 antibodies link autoimmunity to PAD4 with CTL-associated rheumatoid arthritis 1.00
Whole blood transcriptome profiling in patients treated with deucravacitinib and novel mechanistic insights into TYK2 inhibition in lupus: results from a post hoc analysis of the PAISLEY SLE phase 2 trial 0.89
Myeloid dendritic cell subsets characterise muscle in patients with inclusion body myositis and correlate with the IFN-γ pathway and effector T cell markers 0.47
Deep profiling of lupus nephritis kidneys reveals dynamic changes in myeloid cells associated with disease progression 1.00
Human hypofunctional NCF1 variant aggravates salivary gland immunopathology in Sjögren’s disease by promoting switched memory B-cell recruitment and long-lived plasma cell differentiation 0.37
Musculoskeletal ultrasound findings in people with asymptomatic hyperuricemia: baseline analysis from the Transitions in Gout Research (TIGER) study using the OMERACT gout ultrasound semiquantitative scoring system 0.10
Frequency and characteristics of axial involvement in psoriatic arthritis: results from the International Multicentre AXIS Study 0.10
Neutrophil transcriptomics in SLE reveals intrinsic disease signatures, shared ex vivo adaptation, and transcriptional reset after CAR T-cell therapy 0.89
A novel murine model of early calcium pyrophosphate deposition disease based on the TNFRSF11B mutation mimics features of the human disease 1.00
Microbial signatures in psoriatic arthritis distinguish disease phenotypes and newly diagnosed inflammatory bowel disease independent of faecal calprotectin 0.21
A phase 2, randomised, placebo-controlled study of guselkumab in adults with new-onset or relapsing giant cell arteritis 0.36
Safety and immunogenicity of the recombinant zoster vaccine in patients with rheumatoid arthritis using abatacept: a pilot multicentre, double-blind, randomised controlled trial 0.86
The incidence of interstitial lung disease in patients with systemic sclerosis: rate, risk factors and prognostic implications in a EUSTAR cohort analysis (CP 133) 0.03
A genetic variant of BAFF is associated with the risk of lymphoma in Sjögren disease 0.20
Type I interferon endotypes drive divergent clinical trajectories in childhood-onset SLE uncovered through a novel systems immunology approach 0.24
Antimitochondrial antibodies in systemic lupus erythematosus are associated with and predict nephritis, arterial vascular events, and mortality 0.35
RUNX1 is expressed in a subpopulation of dermal fibroblasts and is associated with disease severity of systemic sclerosis 1.00
A de novo dominant-negative PSMB8 mutation causes severe CANDLE/PRAAS due to arrested proteasome biogenesis 0.30
Effects of clofutriben, a selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, on the efficacy and toxicity of prednisolone in patients with polymyalgia rheumatica: a single-blind controlled trial with sequential cohorts 0.42
CD3+ immune cell endotypes are associated with PsA disease phenotype and response to advanced therapy: an integrated mass cytometry and proteomics cohort study 0.09
Inadequate response to anti-TNFα therapy is associated with a gain-of-function TNFR2-R polymorphic variant in patients with psoriatic arthritis 1.00
Tirzepatide and change in uric acid and its association with weight reduction: post hoc analyses of the SURMOUNT-1 randomised placebo-controlled trial 0.67
Spatial profiling of giant cell arteritis tissues reveals immune heterogeneity and potential predictors of glucocorticoid response 0.22
Entheseal tissue signature in response to IL-17A inhibition in psoriatic arthritis: results from the EBIO entheseal biopsy study 0.03
Innate immune cell subsets are enriched in synovial fluid of ACPA-negative rheumatoid arthritis and characterized by distinct type I IFN gene signatures 0.24
Short-chain fatty acids and their gut microbial pathways distinguish rheumatoid arthritis in discordant monozygotic twins 0.82
Inhibition of structural damage progression with the selective interleukin-23 inhibitor guselkumab in participants with active PsA: results through week 24 of the phase 3b, randomised, double-blind, placebo-controlled APEX study 0.67
Myositis-specific autoantibodies recognising Mi2 also target the AIRE protein at a shared PHD zinc finger 0.88
Discovery of tissue-specific proteomic signatures in juvenile dermatomyositis highlights pathways reflecting persistent disease activity, clinical heterogeneity, and myositis-specific autoantibody subtype 1.00
Identification of a novel transcriptome signature for predicting the response to anti-TNF-α treatment in patients with rheumatoid arthritis 0.07
SLE classification criteria item relationships: implications on SLE as a disease entity 0.20
Mycophenolate mofetil plus methotrexate versus cyclophosphamide with sequential azathioprine for treatment of Takayasu arteritis 0.05
Transcriptomic profiling of Sjögren’s disease salivary glands identifies signatures associated with both follicular and extrafollicular responses linked to rheumatoid factor and anti-La/SSB seropositivity 0.28
Chondrocalcinosis and incident knee osteoarthritis: findings from 2 large prospective cohorts with 20 years of follow-up 0.41
HLA loci heterozygosity modulates genetic risk in idiopathic inflammatory myopathies 0.34
A glossary of signs and symptoms of giant cell arteritis 0.34
Highly selective tyrosine kinase 2 inhibition with zasocitinib (TAK-279) improves outcomes in patients with active psoriatic arthritis: a randomised phase 2b study 0.78
Antimitochondrial antibodies in systemic sclerosis target enteric neurons and are associated with GI dysmotility 1.00
Exploring the limit of image resolution for human expert classification of vascular ultrasound images in giant cell arteritis and healthy subjects: the GCA-US-AI project 0.11
20 18.47
Feasibility and Validity of a Remotely-Administered 30-Second Sit-to-Stand in People with Multiple Sclerosis 1.00
Fall Injury Avoidance Strategy Scale (FIAS) – Validation of a Scale to Quantify Fall-Related Protective Movements 1.00
Estimation of Endurance During Elbow Flexion with Myoelectric Orthotic Assistance 1.00
Daily Temporal Associations Between Use of Psychoactive Substances and Fatigue, Pain, Stress, and Depressive Symptoms in People With Multiple Sclerosis 1.00
Relationships of Substance Use Disorders With Discharge Outcomes After Inpatient Rehabilitation: A Retrospective Cohort Study 1.00
Effects of a Bone-Strengthening Exercise Intervention on Bone Health in Pediatric Cancer Survivors: A Randomized Controlled Trial 0.15
Trends in Opioids and Non-Pharmacologic Pain Management among U.S. Cancer Survivors, 2011–2020 1.00
Practice Guideline for Methylphenidate Use in Persons with Traumatic Brain Injury: Report of the American Congress of Rehabilitation Medicine 1.00
Improved tracking of mobility across care settings: a crosswalk between AM-PAC mobility ‘6-clicks’ and GG Items 1.00
Health related quality of life and factors predicting impairment following intensive interdisciplinary pain treatment among children with chronic pain 1.00
Perineuromal Botulinum Toxin Injection for War-Related Postamputation Pain: A Pragmatic, Multicenter, Comparative Effectiveness Study 0.50
Validity of Scores from the 12-Item Multiple Sclerosis Walking Scale Among Young, Middle-Aged, and Older Adults with Multiple Sclerosis 1.00
Fear-Avoidant Adults Have Worse Clinical Outcomes and Recovery Time Following Concussion 1.00
The relationship between physical activity domains by level and illness intrusiveness in people with multiple sclerosis 1.00
Microdialysis Evaluation of Blood Flow, Lactate, and Glucose in Active Trigger Points of Tension-Type Headache Patients and Latent Trigger Points in Healthy Muscle 1.00
Post-Acute COVID-19 Syndrome: Brain Fog Phenotype, Patient Centric Understanding and Biopsychosocial Oriented Treatment 0.82
Acoustic Measures of Voice Perturbation Offer Limited Value as Standalone Indicators of Laryngeal Penetration or Aspiration 1.00
Quantifying Exercise Intensity to Predict Changes in Walking Capacity in People with Chronic Stroke 1.00
Temporal Association Between Reported Use of Psychoactive Substances and Cognitive Function in People with Multiple Sclerosis 1.00
Prevalence and Characteristics of Prehabilitation Utilization among Older Medicare Beneficiaries Undergoing Elective Inpatient Lower Extremity Joint Replacement 1.00
71 50.40
A Pragmatic Trial of a Shared Decision-Making Intervention to Improve Medication Adherence and Outcomes in Systemic Lupus Erythematosus: The HCQ-SAFE Study 1.00
Glomerular endothelial rarefaction associated with hypoxic neutrophils marks renal pathology activity in lupus nephritis 1.00
Cytokine Profiling of Systemic Sclerosis‐related Pulmonary Hypertension 1.00
T cell plasticity in systemic lupus erythematosus revealed by large‐scale T cell receptor repertoire and transcriptome studies 0.17
Differences in SARS‐CoV‐2 antigen persistence in individuals with systemic autoimmune rheumatic diseases compared to the general population: A RECOVER‐Adult Cohort Study 1.00
Association of Epigenetic Trajectory With Development of Clinical Rheumatoid Arthritis in Individuals With Anti–Citrullinated Protein Antibody Positivity: Targeting Immune Responses for Prevention of Rheumatoid Arthritis (TIP-RA) 1.00
High‐resolution deep learning DIXON MRI of the sacroiliac joints is non‐inferior to standard MRI in patients with suspected axial Spondyloarthritis 0.04
Integrative Multi‐omics Approaches Identify Biomarkers Associated with Progression from Arthralgia to Rheumatoid Arthritis 0.04
Tissue Damage in Rheumatoid Arthritis Is Genetically Linked to Low Peptidylglycine Alpha‐Amidating Monooxygenase Activity in Synovial Fibroblasts 0.15
Inferring rheumatoid arthritis disease activity status from the electronic health records across health systems 1.00
CD14 Plays a Critical Role in Pain and Inflammation Across Multiple Models of Post-traumatic Osteoarthritis 1.00
Effective Performance of the 2022 American College of Rheumatology/EULAR Classification Criteria for Antineutrophil Cytoplasmic Antibody–Associated Vasculitis in Pediatric Patients: An ARChiVe Study 0.39
Tissue‐Specific and Spatially Dependent Metabolic Signatures Perturbed by Injury in Male and Female Mice 1.00
Subsets of Patients With Lupus Identified by Gene Expression Profiles Exhibit Differential Clinical Responsiveness to Baricitinib 1.00
Nerve growth factor is sufficient to cause multiple osteoarthritis‐relevant pathological features in naïve murine knee joints 0.93
18F‐Fluorodeoxyglucose Positron Emission Tomography Imaging Assessment within a Randomized Controlled Trial in Giant Cell Arteritis 0.42
Skin Transcriptomics Reveal Shared Molecular Mechanisms for Skin and Lung Involvement in Systemic Sclerosis 1.00
ANK1 and EPB41 Variants and the Risk of Steroid-Induced Osteonecrosis 0.14
Improved Detection of Myositis‐Specific Autoantibodies Using Luciferase Immunoprecipitation Systems Assay: Comparison With Line Blot and Conventional Immunoprecipitation 1.00
Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial 0.80
Identifying systemic lupus erythematosus from serum proteomic profiles using machine learning and genetic risk stratification 1.00
Combination Therapy in Participants With Active Psoriatic Arthritis Using Subcutaneous Guselkumab and Golimumab: Week 24 Results From a Phase 2a, Multicenter, Randomized, Double-Blind, Proof-of-Concept Study 0.69
Dysregulation of U12-Type Splicing in Lupus Neutrophils 1.00
Spondyloarthritis Preceding and Following Inflammatory Bowel Disease Diagnosis and Risk Factors: A Temporal Trends Analysis in a Population‐Based Cohort 0.52
Association of Clonal Hematopoiesis With Incident, Late‐Onset, Seropositive Rheumatoid Arthritis 0.89
Coverage Generosity of Novel Antirheumatic Drugs in Medicare Advantage and Stand‐Alone Part D Plans 1.00
Investigating the Role of Type I Interferon Signaling on Muscle Disease Using Mouse Models 1.00
Telocyte Deletion is Associated with Loss of Lymphatic Drainage and Exacerbation of Inflammatory‐Erosive Arthritis in Mice 1.00
Anifrolumab Treatment Leads to Rapid Reduction in Urinary Biomarkers of Intrarenal Inflammation in Lupus Nephritis: Results From the Phase 2 Randomized Trial 0.44
A Metabolomic Signature Predicts Gout Flare Clinical Outcome Associated With Colchicine Prophylaxis 0.07
Multimodal Integration of Protein Interactomes With Genomic and Molecular Data Discovers Distinct Rheumatoid Arthritis Endotypes 1.00
TWEAK/Fn14 Signaling Drives Oxidative Cardiac Injury in Systemic Lupus Erythematosus: Evidence From Patient Biomarker Studies, Lupus Mouse Models, and Cardiomyocyte Assays 0.08
Baseline Interleukin‐10 Levels as a Predictive Biomarker for Achieving Clinical Response With Abatacept in Patients Who Were Disease‐Modifying Antirheumatic Drug Naive and Anti–Citrullinated Protein Antibody Positive With Early Rheumatoid Arthritis 0.80
Multi‐Omic Profiling Reveals Immune Cell Priming Signature Linked to Lupus Prognosis 0.96
Efficacy and Safety of Guselkumab in Participants With Active Psoriatic Arthritis After Inadequate Response to One Prior Tumor Necrosis Factor Inhibitor: Week‐24 Results of a Phase 3, Randomized, Placebo‐Controlled Study 1.00
Integrative single cell RNA-sequencing and spatial transcriptomics uncovers distinct macrophage-fibroblast cross-talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis 1.00
Measuring the Impact: MRI Response of Sacroiliac Joints to TNF Inhibitors in Youth with Axial Disease 0.89
Deficiency of AP1M2 causes a new autoinflammatory disease with colitis 0.47
DNA methylation profiling reveals distinct epigenetic clusters and suggests epigenetic patterns associated with sex and disease activity in childhood‐onset lupus 0.18
Risk factors for relapse in ANCA-associated vasculitis among patients with relapse after induction of remission with rituximab 0.80
Immunological Profiling suggests an Association between Treg dysfunction and Pain in Knee Osteoarthritis 0.04
The relation of colchicine to total joint arthroplasty among people with gout in a population‐based cohort study 0.92
Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand? 0.36
Tofacitinib for the Treatment of Juvenile Idiopathic Arthritis: Patient‐Reported Outcomes in a Phase III, Randomized, Double‐Blind, Placebo‐Controlled Withdrawal Trial 0.52
HLA‐DQA1*01:02 is associated with antibody multi‐reactivity with citrulline‐containing type II collagen epitopes while HLA‐DRB1*04:01 is associated with more private antibody reactivity with citrulline‐containing IgG epitopes in rheumatoid arthritis 1.00
Identification of risk factors for incident left ventricular systolic dysfunction and predictors of cardiac recovery in patients with systemic sclerosis 1.00
Longitudinal Changes in Serum Urate Levels from Pre‐menopause through Post‐menopause: Interrupted Time‐Series Analyses 0.45
Telomere Length of Peripheral Blood Leukocytes Predicts Disease Severity and Worse Survival in Systemic Sclerosis 0.86
A randomized, placebo‐controlled trial of hydroxychloroquine in incomplete lupus 1.00
Interleukin‐23 receptor deficiency in podocytes averts the development of lupus nephritis. 1.00
Where we Live matters: Varied Disease Burden and Treatment Patterns in Psoriatic Arthritis in the United States 1.00
Skin biopsies enhance prediction of clinical trajectory in diffuse cutaneous systemic sclerosis 1.00
Efficacy and Safety of ABBV-154 for the Treatment of Active Rheumatoid Arthritis: A Phase 2b, Randomized, Placebo-Controlled Trial 0.64
Longitudinal Autoantibody and Proteomic Profiles Uncover Biomarkers and Mechanisms of Disease Progression in Systemic Sclerosis 0.03
Clinical Impact of Multiparametric Contrast‐Enhanced Dual‐Energy Computed Tomography in Arthritis Imaging: A Prospective Single‐Center Study 0.10
Epidermal Interferon kappa drives cutaneous lupus‐like lesions, photosensitivity and systemic autoimmunity iin vivo/i 1.00
Peripheral Biomarker Signatures in Rheumatoid Arthritis–Associated Interstitial Lung Disease 1.00
Risk of serious infection in patients with rheumatoid arthritis‐associated interstitial lung disease or bronchiectasis: A comparative cohort study 0.91
Distinct Cancer Risk Profiles in Patients with Systemic Sclerosis with Autoantibody Stratification 1.00
Precision Medicine in Pediatric Autoimmunity: Leniolisib Treatment of Childhood‐Onset Lupus Nephritis Due to Activated Phosphoinositide 3‐Kinase δ Syndrome 1.00
Hand Swelling and Other Non–Raynaud Phenomenon Symptoms as the Initial Presentation of Systemic Sclerosis: Prevalence and Clinical Associations in Two scpUS/scp Cohorts 1.00
ADAM9 promotes glycolysis in Th17 cells and autoimmunity through activation of IGF‐1 signaling 0.79
Effect of Long‐Term Voclosporin Treatment on Renal Histology in Patients With Active Lupus Nephritis With Repeat Renal Biopsies 0.50
Deficiency of cartilage‐specific Y‐box binding protein 1 represses NF‐κB signaling and alleviates osteoarthritis progression 0.17
Familial Aggregation in Psoriatic Arthritis: Phenotypic Differences in Patients with and without a Family History of Psoriatic Disease 1.00
Three‐Year Outcomes and Latent Class Trajectory Analysis of the Childhood Arthritis and Rheumatology Research Alliance Polyarticular scpJIA/scp Consensus Treatment Plans Study 0.78
Complex Regulatory Interactions at scpiGDF5/i/scp Shape Joint Morphology and Osteoarthritis Disease Risk 1.00
Differences in Dynamics of Specific Antinuclear Antibodies and Their Susceptibility to B Cell–Targeting Treatment in Patients With Systemic Lupus Erythematosus 0.47
Three‐Year Results of Tapering Tumor Necrosis Factor Inhibitor to Withdrawal Compared to Stable Tumor Necrosis Factor Inhibitor Among Patients With Rheumatoid Arthritis in Sustained Remission: A Multicenter Randomized Trial 0.05
A tolerogenic plasmid inhibits autoantibody production triggered by immunization with human peptidyl arginine deiminase 4. 0.32
A randomized, double‐blind, placebo‐controlled trial of abatacept for the treatment of relapsing, non‐severe, granulomatosis with polyangiitis 0.63
6 3.96
A retrospective, real-world study of IV iron use to treat iron deficiency anemia during acute infection 1.00
Plasmodium knowlesi can adapt to infect Duffy-negative erythrocytes 0.12
Single-cell profiling of ANKRD26 thrombocytopenia reveals progenitor expansion and polyploid apoptosis via JUNB-p21 0.04
BRAFV600E-positive mononuclear cells in blood at diagnosis portend treatment failure and neurodegeneration in pediatric LCH 1.00
Single-cell and clonal analysis of AL amyloidosis plasma cells and their bone marrow microenvironment. 0.80
Novel regulators of GVHD revealed through microbiome and metabolome patterns across distinct intestinal regions 1.00
11 4.82
Biosignatures of cognitive basic symptoms mark a distinct neurodevelopmental pathway to schizophrenia 0.03
Predictive models for ataxia progression and conversion in spinocerebellar ataxia type 1 and 3 0.67
Staging Alzheimer’s disease through amyloid and tau PET 1.00
Aβ low threshold mechanoreceptors contribute to sensory abnormalities in fibromyalgia 0.10
Biallelic variants in iCOX18/i cause a mitochondrial disorder primarily manifesting as peripheral neuropathy 0.05
Connectivity as a universal predictor of tau progression in atypical Alzheimer’s disease 0.39
Cognitive loss after brain trauma results from sex-specific activation of synaptic pruning processes 0.92
Combined genomics and proteomics unveils elusive variants and vast aetiologic heterogeneity in dystonia 0.02
Alzheimer and cardiovascular genetic scores and cognition: the FINGER randomized controlled trial 0.01
Genome-wide association study of neuropathological features in Lewy body disease 1.00
Sleep, pericyte subtypes and cognitive decline in adults with and without Alzheimer’s disease 0.64
4 0.45
Presacral tumours: international consensus on diagnosis and management 0.20
Outcomes after elective inguinal hernia repair with mesh performed by associate clinicians versus medical doctors in Sierra Leone: 5-year follow-up of a randomized clinical trial 0.10
Endovascular aortic arch repair with a triple branch arch device 0.08
Impact of bariatric surgery on patients with chronic kidney disease and severe obesity: multiple-linked population-based cohort study 0.07
1 0.68
Multi-omic profiling of intraductal papillary neoplasms of the pancreas reveals distinct patterns and potential markers of progression 0.68
2 2.00
Spermine Oxidase Serves as a Key Functional Node in Microbial Dysbiosis–Induced Breast Carcinogenesis 1.00
Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models 1.00
30 19.73
A comparison of deep multiomics profiles across ethnicity, geography, and age 0.68
Mechanism-guided identification of antidepressant G protein-coupled receptor drug targets 0.95
Systematic discovery of pro- and anti-HIV host factors in primary human CD4+ T cells 0.99
Gut microbiome is associated with recurrence-free survival in patients with resected high-risk melanoma receiving adjuvant immune checkpoint blockade 1.00
Arbitrium phages can manipulate each other’s lysis/lysogeny decisions 0.06
Controlled human influenza infection reveals heterogeneous expulsion of infectious virus into air 0.93
Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy 0.04
Microbiome-produced nicotinic acid controls colon regional identity and injury susceptibility 0.88
Selective targeting of endothelial and perivascular angiocrine ROCK2 treats liver fibrosis 0.05
Liver exerkine reverses aging- and Alzheimer’s-related memory loss via vasculature 1.00
Establishing the relationship between brain cellular senescence and brain structure 1.00
Butyrolactol A enhances caspofungin efficacy via flippase inhibition in drug-resistant fungi 0.29
Stimulant medications affect arousal and reward, not attention networks 1.00
In vivo transcriptomic, functional, circuit-based, and translational analyses of enteric neurons 1.00
Psilocybin triggers an activity-dependent rewiring of large-scale cortical networks 0.85
Properties and functions of transcriptionally distinct enteric neurons 1.00
Single-cell susceptibility to viral infection is driven by variable cell states 1.00
Genetic modifiers and ascertainment drive variable expressivity of complex disorders 0.25
Mining the CD4 antigen repertoire for next-generation tuberculosis vaccines 0.95
A generative deep learning approach to de novo antibiotic design 0.79
Bronze Age Yersinia pestis genome from sheep sheds light on hosts and evolution of a prehistoric plague lineage 0.15
Microbiota-derived inosine programs protective CD8+ T cell responses against influenza in newborns 1.00
Kiwa is a membrane-embedded defense supercomplex activated at phage attachment sites 0.47
Structural insights into brain thyroid hormone transport via MCT8 and OATP1C1 1.00
Combination antiretroviral therapy and MCL-1 inhibition mitigate HTLV-1 infection in vivo 0.02
Structures of the measles virus polymerase complex with non-nucleoside inhibitors and mechanism of inhibition 0.06
Systematic profiling reveals betaine as an exercise mimetic for geroprotection 0.01
Neuroendocrine circuit for sleep-dependent growth hormone release 1.00
Trichophyton concentricum fungal infections and skin microbiomes of Indigenous Peninsular Malaysians 0.57
Microbiome mismatches from microbiota transplants lead to persistent off-target metabolic and immunomodulatory effects 0.75
26 22.41
A CRISPR activation screen identifies SPART as a pan-orthoflavivirus restriction factor 0.09
A fungal pathobiont promotes Streptococcus vaginal persistence and pathogenesis through physical and metabolic interactions 0.75
Maternal helminths rewire the microbiota to promote offspring antiviral immunity 1.00
Childhood immunological imprinting of cross-subtype antibodies targeting the hemagglutinin head domain of influenza viruses 1.00
The skin microbiota drives cutaneous immune checkpoint inhibitor toxicity in genetically susceptible mice 1.00
Chemical inhibition of a bacterial immune system 0.57
Transitions in lung microbiota landscape associate with distinct patterns of pneumonia progression 1.00
A commensal bacterium secretes effector proteins to establish population heterogeneity in the gut 1.00
Diet modulates Vibrio cholerae colonization and competitive outcomes with the gut microbiota 1.00
A Bacteroides fragilis protease activates host PAR2 to induce intestinal pain and inflammation 0.70
The microbiota extends the reproductive lifespan of mice by safeguarding the ovarian reserve 1.00
Gut microbiota and metabolites drive chronic sickle cell disease pain in mice 1.00
A prophage intercepts pathogenic activity of infecting phage for defense 1.00
Macrophages orchestrate elimination of Shigella from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-γ 1.00
Cryptosporidium parvum multidrug resistance protein confers resistance to toxic gut microbial metabolite 0.69
Pseudomonads coordinate innate defense against viruses and bacteria with a single regulatory system 1.00
Metabolic cross-feeding of a dietary antioxidant enhances anaerobic energy metabolism by human gut bacteria 1.00
Amino acid competition shapes Acinetobacter baumannii gut carriage 1.00
Metagenomic selections reveal diverse antiphage defenses in human and environmental microbiomes 1.00
The prototypic crAssphage is a linear phage-plasmid 1.00
Restoration of the human skin microbiome following immune recovery after hematopoietic stem cell transplantation 1.00
Systematic, high-throughput characterization of bacteriophage gene essentiality on diverse hosts 1.00
Microbial contribution to metabolic niche formation varies across the respiratory tract 1.00
Phage arabinosyl-hydroxy-cytosine DNA modifications result in distinct evasion and sensitivity responses to phage defense systems 0.03
Targeted inhibition of pathobiont virulence factor mitigates alcohol-associated liver disease 0.59
E. coli prophages encode an arsenal of defense systems to protect against temperate phages 1.00
7 2.25
Semaglutide ameliorates osteoarthritis progression through a weight loss-independent metabolic restoration mechanism 0.05
Ketogenic diet alleviates septic lung injury via microbial gut-lung axis 0.03
Gut microbiota-derived isovaleric acid alleviates atrial fibrillation by suppressing GSDME-dependent pyroptosis 0.05
Blood-flow restriction resistance training improves skeletal muscle mitochondrial capacity and cardiovascular risk factors in type 2 diabetes 0.08
Therapeutic remodeling of the ceramide backbone prevents kidney injury 1.00
Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication 0.15
FGF21 promotes longevity in diet-induced obesity through metabolic benefits independent of growth suppression 0.90
2 1.91
Randomized phase 2b dose-escalation trial of stem cell therapy with laromestrocel for aging frailty 0.96
A phenotypic brain organoid atlas and biobank for neurodevelopmental disorders 0.95
3 2.25
Development of a glutamine-responsive MRI contrast agent 1.00
Cefiderocol “under siege”? Understanding the rise of NDM-mediated resistance to novel agents 0.45
Ultra-high resolution magnetic resonance microscopy of iin situ/i gadolinium gold nanoparticle-labeled cells in the rat brain 0.80
20 15.94
Cone Beam CT Imaging-Guided Bronchoscopy vs CT Imaging-Guided Transthoracic Needle Biopsy for Peripheral Pulmonary Lesion Diagnosis 1.00
Diaphragm Thickening Fraction Fails to Predict Esophageal Pressure or Ventilator Weaning in Children 1.00
Evaluation of Lung Disease in Adults With Osteogenesis Imperfecta 1.00
Diagnostic Yield of CT Imaging and Point-of-Care Ultrasound After In-Hospital Cardiac Arrest 1.00
Timely Antibiotics and Fluid Resuscitation Are Associated With Increased Discharge to Home After Sepsis 1.00
The Impact of Weight Loss on the Physiological Endotypes Associated With OSA 0.12
Daily Physical Activity in Pulmonary Arterial Hypertension 1.00
Associations between Prior Lung Diseases and Risk of Lung Cancer in Populations With No Smoking History: A Systematic Review and Meta-Analysis 0.92
“Lateral Decubitus Strategy (LADS) is Superior to Ventilatory Strategy (VESPA) in Preventing Atelectasis from Obscuring Targets during Robotic Bronchoscopy, Leading to Improved Procedural Outcomes” (LADS vs VESPA Trial) 1.00
Adjunctive Corticosteroid Use and Clinical Outcomes in Non-HIV Pneumocystis jirovecii Pneumonia 1.00
Post-ICU Care Trajectories and Outcomes Among Veterans: Comparing VA and Community Hospital Discharges 1.00
Pleural Manometry in Pneumothorax: Evaluating Tension Physiology and Predicting Outcomes 1.00
Post Intensive Care Syndrome Awareness and Communication: Surveys of ICU Providers and Patients 1.00
Poor olfaction is associated with lower pulmonary function in older adults 0.95
Comparative Effectiveness of Tocilizumab Versus Rituximab in RA-ILD: A Emulated Target Trial 0.14
Contribution of Key Comorbidities to Unfavorable Treatment Outcomes among Adults with Drug-sensitive Pulmonary Tuberculosis in India: a Prospective Cohort Analysis 0.54
The Consistency of Hypercapnic Respiratory Failure Case Definitions in Electronic Health Record Data 1.00
Contemporary Trends in Pediatric Extubation Failure and Non-Invasive Respiratory Support Use 1.00
Low tidal volume ventilation and mortality in patients with acute brain injury: a secondary analysis of an international observational study* 0.20
Covert triage during the COVID-19 pandemic: A qualitative analysis of rationing in intensive care 0.07
17 11.51
Microplastic Exposure Aggravates Cardiomyopathy Under Hemodynamic Stress Through the Gut-Heart Axis 0.10
Association of Common Ancestry-Enriched Variants With Cardiomyopathy and Arrhythmias 1.00
Comparative Efficacy of Transfusion Strategies in Women and Men With Myocardial Infarction and Anemia: Prespecified Secondary Findings From the MINT Trial 0.57
Resuscitation From Out-of-Hospital Cardiac Arrest: When Is EtCO2 Reliably Associated With ROSC? 0.75
Intramuscular Adipose Tissue Accumulation is a Key Determinant of Limb Function in Peripheral Artery Disease. 1.00
TRPM7 Deficiency Protects Against Myocardial Ischemia-Reperfusion Injury by Regulating Intracellular Zn2+ Homeostasis. 0.91
Cell-Specific Inducible Human APOL1 Risk Variant Expression in Mice Causes Hypertension and Renal Damage. 0.91
N-Palmitoyl Glutamine Is a Candidate Mediator of Cardiorespiratory Fitness. 1.00
Coramitug, a Humanized Monoclonal Antibody for the Treatment of Transthyretin Amyloid Cardiomyopathy: a Phase 2, Randomized, Multicenter, Double-Blind, Placebo-Controlled Trial. 0.47
High-Dose vs. Standard-Dose Influenza Vaccine and Cardiovascular Outcomes in Older Adults: The FLUNITY-HD Prespecified Pooled Analysis. 0.17
Randomized Controlled Trial of Mechanical Thrombectomy With Anticoagulation Versus Anticoagulation Alone for Acute Intermediate-High Risk Pulmonary Embolism: Primary Outcomes from the STORM-PE Trial. 0.71
Microvascular Endothelial Cells License APS Vasculopathy Through YAP1- and CCN2-Mediated Signaling. 0.75
Impacts of Reducing Sitting Time or Increasing Sit-to-Stand Transitions on Blood Pressure and Glucose Regulation in Postmenopausal Women: Three-Arm Randomized Controlled Trial. 0.85
PIEZO1 Overexpression in Hereditary Hemorrhagic Telangiectasia Arteriovenous Malformations. 0.97
Subclinical Primary Aldosteronism and Major Adverse Cardiovascular Events: A Longitudinal Population-Based Cohort Study. 0.08
Nonculprit Vulnerable Plaques and Prognosis in Myocardial Infarction With Versus Without ST-Segment Elevation: A PROSPECT II Substudy 0.29
High Dietary Phosphate Intake Induces Hypertension and Sympathetic Overactivation Through Central Fibroblast Growth Factor Receptor Signaling. 1.00
90 67.69
Risk of Measles Outbreak in Texas School Districts: A Modeling Study 1.00
Diagnostic Yield of Tongue Swab- Compared to Sputum-Based Molecular Testing for Tuberculosis in Four High-Burden Countries 0.25
Epidemiology of Pediatric Invasive Group A Streptococcal Infections in 10 U.S. States, 2004–2023 1.00
Challenges in malaria diagnosis and treatment in Kinshasa Province, Democratic Republic of the Congo 0.53
Impact of Procalcitonin Testing on Antibiotic Use in Patients Hospitalized With Community-Acquired Pneumonia: A Multi-Hospital Cohort Study 1.00
Empirical Antibiotic Activity and Outcomes in Pediatric Gram-negative Bloodstream Infections: A Rank-based Composite Outcome Analysis 0.05
Trends in Long Duration Antibiotic Prescribing Following Focused Outpatient Antimicrobial Stewardship Efforts Across a Large Healthcare Enterprise 1.00
Comparing the Antimicrobial Resistance Crisis to the Coronavirus Disease 2019 Pandemic: A Randomized Public Health Messaging Experiment 1.00
Mapping Hospitals That Treat Severe Malaria Cases in the United States: Evidence to Inform Health Systems Strategies for Intravenous Artesunate Supply 1.00
Age-Specific Risk of Herpes Zoster in Adults Aged ≥18 Years With Comorbid Conditions—A Retrospective Cohort Study in the United States 0.83
The population-level impact of doxycycline post-exposure prophylaxis on syphilis in King County, WA: an interrupted time series analysis 1.00
Frequent Plasmodium ovale Recurrence in Coastal Tanzania 0.75
Prevalence and Predictors of Tuberculosis in Adults and Adolescents With Sputum Trace Ultra Results in 2 High-Burden Clinical Settings 0.50
A 48-Week, Randomized Controlled Trial of Doravirine for Individuals With HIV and Obesity on Integrase Inhibitors and Tenofovir Alafenamide: The Do IT Study (ACTG A5391) 0.81
Evaluation of the impact of universal mupirocin decolonization in intensive care units on the utility of MRSA PCR nasal swab testing 1.00
Antiretroviral Activity, Pharmacokinetics, and Safety of MK-8527, an Oral Nucleoside Reverse Transcriptase Translocation Inhibitor, in Adults Living With HIV-1 Who Had Not Previously Taken Antiretroviral Agents: Results From Two Open-Label, Phase 1 Studies 0.55
Cephalosporins Versus Non-Cephalosporin Antibiotics for Perioperative Prophylaxis in Primary Arthroplasty: A Systematic Review and Meta-Analysis 0.90
Safety and Tolerability of Oral Islatravir Once Monthly as Pre-Exposure Prophylaxis in Cisgender Men and Transgender Women Who Have an Elevated Likelihood of HIV-1 Exposure: Results From the IMPOWER-24 Randomized Phase 3 Study 0.62
Patterns of HIV-1 Viral Load Suppression and Drug Resistance During the Dolutegravir Transition: A Population-based Longitudinal Study 0.32
Using Probability of Community-Acquired Pneumonia to Tailor Antimicrobials Among Inpatients: A Pragmatic, Randomized Trial 1.00
Progression risk in cancer patients with HIV compared to cancer patients without HIV 1.00
Escherichia coli ST131 Drives Carbapenem Use for E. coli Bloodstream Infections 1.00
Indirect Influenza Vaccine Effectiveness Under Randomized Conditions: A Systematic Review and Meta-Analysis 0.75
A Public Health Approach to Antimicrobial Stewardship in Long-Term Care Facilities: A Multifaceted Program in Massachusetts 1.00
Fatal Overdose, Acute Viral Hepatitis, and Human Immunodeficiency Virus Attributed to Injection Drug Use, Appalachian Region of the United States, 2000–2023 1.00
Point-of-Care Urine Tenofovir Drug-Level Feedback Counseling Improves Long-term PrEP Adherence for U.S. MSM in Pilot RCT 1.00
Melioidosis Complicated by Native Valve Endocarditis in a Traveler Returning From Thailand to the United States 1.00
Clinical Manifestations, Long-Term Trends, and Risk Factors for Treatment Failure in Native Vertebral Osteomyelitis: A 26-Year Mayo Clinic Experience 0.83
Implementing a Program of Comprehensive Tuberculosis Preventive Treatment: Safety, Effectiveness, and Acceptability of Moxifloxacin or Bedaquiline Use for Contacts Exposed to Drug-Resistant Strains 0.11
Symptomatic and asymptomatic norovirus infections in early life; The PREVAIL Cohort, 2017-2020 1.00
Pregnant women with MDR/RR-TB and the all-oral 6-month regimen: experiences from a patient series in South Africa 0.22
Evaluating the Cepheid Xpert TB/LTBI Research-Use-Only Assay for Detection of Active and Latent Mycobacterium tuberculosis Infection 0.43
Short-Course Tuberculosis Preventive Therapy in a High Migration Setting: Early Experience With 1HP in Cook County, Illinois 1.00
Effect of Direct-from-blood Bacterial Testing on Antibiotics Administration in Adults Presenting With Acute Infection: A Randomized Trial 1.00
<atl>Documenting environmentally acquired iMycobacterium intracellulare/i subsp. ichimaera/i pulmonary disease soon after bronchiectasis onset</atl> 1.00
Overlapping Clinical Presentation of Long COVID and Postacute COVID-19 Vaccination Syndrome: Phenotypes, Severity, and Biomarkers 1.00
Integrating HIV and Stimulant Use Disorder Treatment: A Pilot Implementation Effectiveness Trial of Contingency Management in HIV Care 1.00
Evaluation of a Remote Therapeutic Monitoring (RTM) Device and Integrated Care Platform in Outpatient Parenteral Antimicrobial Therapy (OPAT) 1.00
Early symptom response in patients with uncomplicated urinary tract infection treated with gepotidacin or nitrofurantoin: pooled analysis from two pivotal Phase 3 studies 0.50
Using the Comparing Oral versus Parenteral Antimicrobial Therapy (COPAT) Clinical Trial to Influence Institutional Practice Transformation Towards Earlier Transition to Oral Antibiotics 1.00
Reproducible Identification of Staphylococcus aureus Bacteremia Clinical Subphenotypes 0.31
The Bounce-Back Effect: What Happens After Cessation of Low-Dose Semaglutide in People with HIV 1.00
Aspergillosis-Attributable Mortality in the United States: Analysis of Death Certificate Data 1.00
Using generative artificial intelligence to identify central line-associated bloodstream infections 1.00
Estimating the Accuracy and Additionality of TB-LAM to Diagnose TB in Children Without HIV (AccuLAM) 0.15
Epidemiology of Vibrio cholerae Infections in the Households of Cholera Patients in the Democratic Republic of the Congo: PICHA7 WASHmobile Prospective Cohort Study 0.47
Effects of a Water, Sanitation, and Hygiene Program on Diarrhea, Cholera, and Child Growth in the Democratic Republic of the Congo: A Cluster-Randomized Controlled Trial of the Preventative Intervention for Cholera for 7 Days (PICHA7 WASHmobile) Mobile Health Program 0.37
Combined use of ibalizumab and lenacapavir for the treatment of multidrug-resistant HIV-1: A case series 1.00
Integrase Strand Transfer Inhibitors for Treatment-experienced Young Adults With Perinatal HIV in the US: Immunologic, Virologic, and Anthropometric Outcomes 1.00
Trends in Persons Prescribed HIV Postexposure Prophylaxis in the United States, 2015–2023 1.00
Long-term clinical, immunologic, and viral reservoir outcomes in children treated with VRC01LS and 10-1074 monoclonal antibodies in the Tatelo Study 0.63
Prophylactic Efficacy of CD388, a Novel Drug–Fc Conjugate, in a Human Influenza A/H3N2 Virus Challenge Model: A Randomized, Controlled Phase 2a Study 0.31
Severity of Clinical Presentation and Outcomes in Hospitalized Adult Patients with Influenza by Type and Subtype, United States—2017–2020 1.00
Randomized Pragmatic Trial of the Comparative Effectiveness of Chicken Egg-Based Inactivated, Mammalian Cell Culture-Based Inactivated, and Recombinant Protein Quadrivalent Seasonal Influenza Vaccines in United States Military Health System Beneficiaries 0.94
Antibody Response in Healthcare Workers During the SARS-CoV-2 Gamma Variant Outbreak in Manaus, Brazil 0.35
Empirical Antifungal Treatment of Critically Ⅲ Patients With Influenza-Associated Acute Respiratory Distress Syndrome: A Propensity Score Weighted Observational Study 0.11
HIV Resistance to Dolutegravir Varies With Coadministered Agents 0.72
Increasing HIV Testing During Gonorrhea and Chlamydia Evaluations in Urgent Care and Emergency Departments: A Large Health System Initiative 1.00
Characterizing Treatment Adherence Trajectories in the endTB Multisite Cohort of Drug-Resistant Tuberculosis Patients: An Application of Group-Based Trajectory Modeling 0.25
The three-gene Xpert Host Response signature for pediatric tuberculosis screening: A prospective diagnostic accuracy study 0.46
Nontuberculous Mycobacterium Skin Infections Associated With One Tattoo Studio—Oregon, January–April 2023 1.00
Design and evaluation of next-generation HIV genotyping for detection of resistance mutations to 28 antiretroviral drugs across five major classes including lenacapavir 1.00
Evaluation of COVID-19 and Influenza-like Illness Surveillance Case Definitions in a Prospective Cohort of Healthcare Personnel in Peru 0.65
Comparing clinical, microbiological and genetic definitions of relapse in patients with subsequent episodes of MRSA bone and joint infection 0.83
Adjuvanted recombinant zoster vaccine is effective against herpes zoster ophthalmicus, and is associated with lower risk of acute myocardial infarction and stroke in adults aged ≥50 years 1.00
Clinical consequences of delaying implementation of long-acting antiretroviral therapy for people with HIV and persistent viremia in the US 1.00
Long-acting cabotegravir/rilpivirine, lenacapavir, and ibalizumab use among persons with HIV-1 viremia at a Ryan White-funded clinic in the urban U.S. South 1.00
Incidence of and Risk Factors for SARS-CoV-2 Infection Among Vaccinated Healthcare Workers During Emergence of SARS-CoV-2 Gamma Variant in the Amazon Region, Brazil, 2021 0.35
Implementation of Diagnostic Stewardship to Improve Urinary Tract Infection Antibiotic Use Across Three Medical Centers 1.00
Sputum and tongue swab molecular testing for the in-home diagnosis of tuberculosis in unselected household contacts: a cost and cost-effectiveness analysis 0.29
Severe Acute Respiratory Syndrome Coronavirus 2 Seroprevalence, Illness Recall, and Work Absenteeism Among Healthcare Workers: A Facility-Based Cross-Sectional Study in the Philippines, 2021 0.31
The Impact of Synergistic Therapy Between Colistin and Meropenem on Outcomes of Patients With Pneumonia or Bloodstream Infection Due to Carbapenem-Resistant Gram-Negative Pathogens 0.58
Oral washes and tongue swabs for Xpert MTB/RIF Ultra-based tuberculosis diagnosis in people with and without the ability to make sputum 0.21
Projecting the Impact and Costs of Near Point-of-Care Tuberculosis Screening Assays in Community-based Active Case Finding 0.55
Protracted SARS-CoV-2 Infection in B-cell Depleted Patients: Immunologic andiral Characteristics and Response to Dual and Extended Antiviral Therapy 0.98
Metagenomic Next-Generation Sequencing of Cerebrospinal Fluid: First Year Experience at a Tertiary Referral Hospital 1.00
Phase 2 Trial of Long-Acting Cabotegravir and VRC07-523LS for Viral Suppression in Adults with HIV-1: ACTG A5357 1.00
Improved consistency of iCandida auris/i colonization screening with an anterior nares and hands composite sample 1.00
A point-of-care prediction tool for recurrent tuberculosis 0.57
Bone Changes With Long-Acting Cabotegravir or Tenofovir Disoproxil Fumarate/Emtricitabine for HIV Prevention in Cisgender Men and Transgender Women: HPTN 083 0.77
SARS-CoV-2 infection increases long-term risk of pneumonia in an urban population: an observational cohort study up to 46 months post-infection 1.00
Prognostic Value of C-Reactive Protein in Adults With Tuberculous Meningitis: A Prospective Cohort Study 0.26
Effectiveness of the Adjuvanted Recombinant Zoster Vaccine in Adults ≥50 Years in the United States 1.00
A real-time urine tenofovir assay improves drug adherence among people with HIV with prior virologic failure in a randomized controlled trial 0.18
Patient perspectives regarding different contact precaution policies for MRSA across two hospitals: patients are in favor of contact precautions 1.00
Effect of Pitavastatin on Epigenetic Aging Biomarkers in People With HIV: Pilot Substudy of the REPRIEVE Trial 0.92
Cumulative antibiotic exposure is associated with ceftriaxone resistance among patients with urinary source Gram-negative bloodstream infection: A retrospective cohort study 1.00
Characteristics Associated with Disseminated Gonococcal Infections vs Uncomplicated Gonorrhea: A California Case-Control Study, 2021-2022 1.00
Incidence of AIDS-defining Conditions among Adults with Perinatally Acquired HIV after Transition to Adult HIV Care in the United States and Canada, 2000-2022 1.00
Stool processing methods for Xpert Ultra testing in childhood tuberculosis: A prospective, multi-country accuracy study 0.22
1 1.00
Paradoxical Positivity and Community Engagement in Online Suicide Discourse 1.00
47 35.20
Traumatic Inflammatory-Coagulation Coactivation Occurs Early After Injury and Impacts Mortality. 1.00
Survey of Intensivist Coverage and Interprofessional Team Staffing in Canadian ICUs 0.14
Red Cell Transfusion in Critically Ill and Noncritically Ill Patients With Acute Myocardial Infarction and Anemia-A Subanalysis of the Myocardial Ischemia and Transfusion (MINT) Trial. 0.78
Comparison of Blood Culture Contamination Rates Between Initial Central Venous Puncture and Catheter Hub Sampling 0.06
Prone Positioning in a North American Cohort of Hypoxemic Patients on Mechanical Ventilation 0.95
Artificial Intelligence Algorithm to Monitor Inspiratory Muscle Effort and Patient-Ventilator Dyssynchrony During Mechanical Ventilation 0.11
Effects of Early Versus Delayed Mechanical Thrombectomy on Outcomes in Intermediate-Risk Acute Pulmonary Embolism. 1.00
Disparities in Finding Delirium in Critically Ill Latinos. 1.00
The Influence of Older Age on RBC Transfusion Decisions in ICU Patients. 0.03
Diastolic Blood Pressure During Pediatric In-Hospital Cardiac Arrest: Trends and Associations With Outcomes. 1.00
Sex-Specific Differences in Tidal Volumes and Mortality of Mechanically Ventilated Patients. 0.09
External Validation, Molecular Signatures, and Therapeutic Relevance of Pediatric Sepsis-Associated Acute Kidney Injury Subphenotypes 1.00
A Modified Delphi Consensus-Based Comprehensive Checklist and Angoff Standard for Assessment of Competency in Brain Death/Death by Neurologic Criteria Determination 1.00
Factors Associated With R01 Submission Among Pediatric Critical Care Medicine Career Development Award Recipients. 1.00
Temperature Control After In-Hospital Cardiac Arrest: Outcomes From the Discover In-Hospital Cardiac Arrest Cohort. 0.88
Exposure to Antipsychotic Medication Is Associated With Less Days Alive and Free From Catatonia in Critically Ill Patients. 1.00
Days Alive and at Home After Critical Illness Hospitalization Among Older Adults and Its Association With Delivery of In-Hospital Rehabilitation. 1.00
Location of In-Hospital Cardiac Arrest: An Updated Analysis of Epidemiology, Emergency Response, and Outcomes. 0.64
Association Between Hospital-Level Volume of Extracorporeal Membrane Oxygenation and Complications: A Clustered, Mixed-Effect Analysis of the Extracorporeal Life Support Organization Registry. 1.00
Machine Learning-Based Return of Spontaneous Circulation Prediction During Cardiopulmonary Resuscitation in a Swine Model of Cardiac Arrest: Effect of Data Resolution and Multimodal Physiological Waveforms 1.00
Utilization of Intensive Care Interventions in Critically Ill Patients With Candidemia Versus Bacteremia: A Multicenter Retrospective Cohort Study 0.97
Conversion From Venovenous to Venoarterial or Hybrid Extracorporeal Membrane Oxygenation: Analysis From the Extracorporeal Life Support Organization Registry. 0.17
Agreement Between Patient and Surrogate Assessments of Pre-Critical Illness Physical Function. 1.00
Recombinant Human Soluble Thrombomodulin and In-Hospital Mortality in Acute Pancreatitis With Disseminated Intravascular Coagulation: A Japanese Nationwide Study. 0.08
An Electronic Health Record-Based Classifier for Moderate-to-Severe Acute Respiratory Distress Syndrome With Persistent Hypoxemia. 1.00
Platelet Transfusion Thresholds for Children Supported by Extracorporeal Membrane Oxygenation: The Extracorporeal Membrane Oxygenation Hemostatic Transfusions in Children (ECSTATIC) Feasibility Clinical Trial. 0.77
Association of Sepsis Survivor Subtypes With Long-Term Mortality and Disability After Discharge: A Retrospective Cohort Study. 1.00
Acute Respiratory Distress Syndrome in Trauma 2007-2019: Comprehensive Patient and Center-Level Retrospective Cohort Analysis. 0.93
Analysis of Mortality and Length of Stay Associated With Implementation of a Large Telecritical Care Program in an Integrated Healthcare System. 1.00
Acute Brain Injury in COVID-19 Versus Influenza A Patients on Venovenous Extracorporeal Membrane Oxygenation: A Propensity Score Matching Analysis of the Extracorporeal Life Support Organization Registry. 1.00
Impact of Left Ventricular Venting on Acute Brain Injury in Patients With Cardiogenic Shock: An Extracorporeal Life Support Organization Registry Analysis. 1.00
Variability in Venovenous Extracorporeal Membrane Oxygenation Candidacy Decision-Making: An International Survey. 0.86
Platelet Transfusion Practices in the ICU: A Prospective Multicenter Cohort Study. 0.04
Optimizing Agreement Between Bedside Nurse-Documented and Trained Researcher Delirium Assessments in the ICU. 1.00
Venovenous Extracorporeal Membrane Oxygenation Cannulation by Intensivists and Surgeons: A Single-Center Retrospective Noninferiority Analysis of Complications and Outcomes From 2018 to 2023. 1.00
Differentiating Lung From Chest Wall Mechanics Is Difficult Without Esophageal Manometry in Children With Acute Respiratory Distress Syndrome. 0.60
Hyperoxia and End-Organ Complications Among Cardiogenic Shock Patients Supported by Veno-Arterial Extracorporeal Membrane Oxygenation. 1.00
An IV Sodium Bicarbonate Shortage in the Critically Ill: An Interrupted Time-Series Analysis. 0.13
Epinephrine Before Defibrillation in Children With Initially Shockable In-Hospital Cardiac Arrest. 1.00
Epidemiology of Substance-Related Admissions to ICUs in the United States. 1.00
Early Vasopressor Utilization in Critically Ill Patients With Acute Traumatic Spinal Cord Injury: A Retrospective Cohort Study. 1.00
Prolonged Mechanical Ventilation Before Venovenous Extracorporeal Membrane Oxygenation and In-Hospital Mortality in Patients With Acute Respiratory Distress Syndrome 1.00
Association Between Driving Pressure and Subsequent Development of Acute Kidney Injury in Acute Respiratory Distress Syndrome. 0.04
Delirium Severity Trajectories in Critically Ill Adults Using the Intensive Care Delirium Screening Checklist: A Population-Based Cohort. 0.44
Pulse Oximetry and Arterial Blood Gas Oxygen Saturation Discrepancies and Mortality in Extracorporeal Cardiopulmonary Resuscitation Patients: An Extracorporeal Life Support Organization Registry Analysis. 1.00
Epidemiology of Septic Shock Associated Acute Kidney Injury: A National Retrospective Cohort Study. 0.50
Early Use of a Risk-Adjusted Mechanical Ventilation Digital Quality Measure Bundle in a Large Health System. 1.00
20 15.16
Evolutionary history of Jamestown Canyon virus reveals complex multi-vector ecology 0.84
Cocaine pollution alters the movement and space use of Atlantic salmon (Salmo salar) in a large natural lake 0.09
Identification of bacterial signals that modulate enteric sensory neurons to influence behavior in C. elegans 1.00
A microbiome-derived olfactory signal regulates inter-male aggression and social dominance in mice 1.00
The evidence for constrained total energy expenditure in humans and other animals 1.00
Oscillatory control of cortical space as a computational dimension 0.92
Psilocybin induces sex- and context-specific recruitment of the stress axis 0.50
Asymmetric lateral habenula function and peripheral neural mechanisms in regulating itch-evoked scratching 1.00
Distinct contributions of anterior and posterior orbitofrontal cortex to outcome-guided behavior 1.00
Nonlinear integration of sensory inputs and behavioral state by a single neuron in C. elegans 1.00
Ultra-endurance athletes and the metabolic ceiling 1.00
Filamentous cheater phages drive bacterial and phage populations to lower fitness 1.00
Dopaminergic projections to the prefrontal cortex are critical for rapid threat avoidance learning 1.00
Conscious awareness determines whether a second learning session disrupts or facilitates earlier learning 0.50
Programmed seasonal brain shrinkage in the common shrew via water loss without cell death 0.18
A circuit from the basolateral amygdala to hippocampal CA3 regulates social behavior 1.00
Excitatory drive to the globus pallidus external segment facilitates action initiation in non-human primates 0.75
Flexible updating of reward and punishment contingencies by VTA GABA neurons 1.00
Disentangling prediction error and value in a formal test of dopamine’s role in reinforcement learning 0.13
Endogenous and exogenous attentional interplay through mixed prefrontal cortex resources 0.25
5 2.74
A non-canonical immunometabolic function of BRD3 during sepsis 0.64
Environmental and genetic risk factors of depression converge on neuronal dysfunction driven by changes in cholesterol homeostasis 0.96
Telocytes deliver essential Wnts directly to murine intestinal stem cells via synapse-like contacts 0.06
Concerted changes in Epithelium and Stroma: a multi-scale, multi-omics analysis of progression from Barrett’s Esophagus to adenocarcinoma 0.93
Therapeutic radiation drives leptomeningeal dissemination of medulloblastoma through an innate immune process 0.15
31 18.56
Ultrarapid Lispro (Lyumjev) Has an Improved Pharmacokinetic Profile for Exercise Compared With Humalog, Resulting in Less Exercise-Associated Hypoglycemia in Adults With Type 1 Diabetes on Open-Loop Continuous Subcutaneous Insulin Infusion. 0.57
Comparative Effectiveness of Tirzepatide Versus Dulaglutide or Semaglutide on Major Cardiovascular Events in Type 2 Diabetes and Cardiovascular Disease: Insights From Two Target-Trial Emulations. 1.00
Everyone or Just Some? Cost-Effectiveness of General Population Versus Targeted Screening Strategies for Type 1 Diabetes in Canada. 0.40
Impact of Metabolic Bariatric Surgery on Weight Loss and Glycemic Control in Adults With Type 1 Diabetes: A Multicenter Retrospective Cohort Study. 0.09
Pathophysiological Risk Factors Preceding Incidence of Type 2 Diabetes Subtypes: A Pooled Cohort Study in the United States. 1.00
Gout-Related Medication Use After Initiating Sodium-Glucose Cotransporter 2 Inhibitors in Patients With Gout and Type 2 Diabetes: Population-Based Target Trial Emulation Studies. 0.59
Global, Regional, and National Estimates of Undiagnosed Diabetes in Adults: Findings From the 2025 IDF Diabetes Atlas. 0.56
Sex Hormones and Cardiovascular Risk in Type 2 Diabetes: Cohort Study of the LookAHEAD Trial. 0.79
Interlaboratory Evaluation of Multiplex Autoantibody Assay Performance in the Islet Autoantibody Standardization Program 2024 Workshop. 0.43
Medication Adherence in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) 1.00
Soluble Urokinase Plasminogen Activator Receptor (suPAR) Mediates the Impact of Diabetes on Adverse Outcomes in Coronary Artery Disease. 0.91
Effect of Semaglutide on Insulin Dose Reduction in Adults With Type 1 Diabetes and Obesity Using Automated Insulin Delivery Systems: ADJUST-T1D Post Hoc Analysis. 1.00
Impact of Oral Semaglutide on Kidney Outcomes in People With Type 2 Diabetes: Results From the SOUL Randomized Trial. 0.27
Effect of Semaglutide on Insulin Sensitivity and Cardiometabolic Risk Factors in Adolescents With Obesity: The STEP TEENS Study. 0.36
Inflammatory and Insulinemic Dietary Patterns and Risk of Type 2 Diabetes Among Women With a History of Gestational Diabetes Mellitus: A Prospective Study of 84,174 Person-Years of Follow-up. 0.34
Novel Phenotypic Clusters of Youth-Onset Type 2 Diabetes Offer No Added Prognostic Value to Simple Clinical Measures. 0.98
Sodium-Glucose Cotransporter-2 Inhibitors, Glucagon-Like Peptide-1 Receptor Agonists, and Frailty Progression in Older Adults With Type 2 Diabetes. 0.92
Association of the Age at Type 2 Diabetes Onset With Diabetes Progression. 0.11
Relationship Between Metabolic and Histological Responses in People With Metabolic Dysfunction-Associated Steatohepatitis With and Without Type 2 Diabetes: Participant-Level Exploratory Analysis of the SYNERGY-NASH Trial With Tirzepatide. 0.80
Effectiveness of an Incentives-Enhanced Stepped Care Intervention Program in Diabetes Prevention in a Multiethnic Asian Prediabetes Cohort: Results From the Pre-DICTED Randomized Controlled Trial. 0.03
Impact of Baseline GLP-1 Receptor Agonist Use on Albuminuria Reduction and Safety With Simultaneous Initiation of Finerenone and Empagliflozin in Type 2 Diabetes and Chronic Kidney Disease (CONFIDENCE Trial). 0.47
Reimagining Acute Diabetes Care: Insights From the Victorian Virtual Emergency Department. 0.08
Longitudinal Metabolic Trajectories in Diabetes Prevention Program Participants Reveal Subgroups With Varying Micro- and Macrovascular Complication Risks. 1.00
Plasma Metabolome, Long-term Body Weight Change, and Type 2 Diabetes in U.S. Individuals. 0.95
Clinical and Demographic Characteristics Associated With Diabetes Remission in Six Integrated Health Care Systems: A Retrospective Cohort Study. 1.00
Effects of Semaglutide With or Without Concomitant Mineralocorticoid Receptor Antagonist Use in Participants With Type 2 Diabetes and Chronic Kidney Disease: A FLOW Trial Prespecified Secondary Analysis. 0.36
Use of the Omnipod 5 Automated Insulin Delivery System Activity Feature Reduces Insulin Delivery and Attenuates the Drop in Glycemia Associated With Exercise in a Randomized Controlled Trial. 0.89
A Multimodal Predictive Model for Chronic Kidney Disease and Its Association With Vascular Complications in Patients With Type 2 Diabetes: Model Development and Validation Study in South Korea and the U.K. 0.07
Impaired Rest-Activity Rhythm Characteristics Predict Higher Risk of Incident Type 2 Diabetes in UK Biobank Participants. 0.38
Benefit of Semaglutide in Symptomatic Peripheral Artery Disease by Baseline Type 2 Diabetes Characteristics: Insights From STRIDE, a Randomized, Placebo-Controlled, Double-Blind Trial. 0.20
Detecting Hyperglycemia Using Biomarkers Versus Continuous Glucose Monitoring. 1.00
6 4.83
Beyond the Surface: Mapping DDE’s Metabolic Footprint on Adolescent Obesity 1.00
Environmentally Relevant Doses of Bisphenol A and S Exposure In Utero Disrupt Germ Cell Programming across Generations Resolved by Single Nucleus Multiomics 0.92
Effects of Extreme Heat Exposure on Heatstroke and Liver Injury in Mice: The Role of PPARα 0.08
Associations of gestational and childhood urinary triclosan concentrations with atopic and allergic symptoms in Health Outcomes and Measures of the Environment (HOME) Study participants ages 1-12 years. 0.91
Beyond the Surface: Mapping DDE's Metabolic Footprint on Adolescent Obesity. 1.00
Environmentally-relevant doses of bisphenol A and S exposure in utero disrupt germ cell programming across generations resolved by single nucleus multi-omics. 0.92
12 7.91
Association of Exposure to Phthalates and Substitutes with Infection Risk Among U.S. Children 0.30
Prenatal Exposure to Gas Stoves, Mold, and Water Damage: Associations With Gestational Duration and Fetal Growth in the ECHO Cohort 1.00
Associations between classroom ventilation rates and school characteristics with indoor air in classrooms during wildfire smoke events 1.00
Molecular and toxicological study of the plasticizers exposure-induced metabolic disorders 0.11
Phthalates, bisphenols, and childhood allergic Phenotypes: Findings from two birth cohort studies 0.07
Exposure to a persistent organic pollutant mixture resulted in sex-specific steatotic liver disease: Role of the liver-endocrine axis 1.00
Psychosocial Stressors as Modifiers of the Associations Between Well-Studied and Understudied Chemicals and Birth Outcomes in the ECHO Cohort 1.00
Novel Bacteroides bacteriophage-like quantitative real-time PCR assays for human sewage pollution measurement 1.00
Phthalate exposure to adult mice alters non-coding RNAs in cauda epididymosomes 1.00
Integrated culture-based and metagenomic profiling of airborne and surface-deposited bacterial communities in residential environments 0.30
Exposome-wide association study of sex-steroid hormones in the U.S. general population: evaluation of complex mixture effects 1.00
Detrimental impacts of chronic bisphenol A (BPA) exposure on follicular signalling modulation and ovulatory competence in zebrafish (Danio rerio) 0.13
12 9.13
Prenatal exposure to phthalates, maternal oxidative stress, and early childhood neurobehavior: a pathway modeling approach 1.00
Exposure to organophosphate esters and trajectories of gestational weight gain: A large prospective cohort study 1.00
Associations between Repeated Measures of Exposure to Phthalates, Phenols, Parabens, and their Mixtures and Metabolic Syndrome in Midlife Women in Mexico City 0.71
Fetal exposure to bisphenols and phthalates and risk of respiratory conditions in infancy. The Generation R Next Study 0.38
Physical exercise mitigates the adverse effects of PM2.5 constituents on lung function: New evidence for inflammatory pathways from a crossover study 0.11
Gestational phthalate levels and biomarkers of aging in infants and children from New York City 1.00
Developmental PBDE exposure persistently impairs mast cell function in vivo and drives sex-specific morphological and transcriptional changes in bone marrow–derived mast cells 1.00
Unraveling the environmental links to feline hyperthyroidism: Insights from silicone passive samplers 1.00
Organophosphate Flame Retardants Disrupt Neurodevelopmental Gene Networks with Autism-Relevant Features: A Multi-Omics Study in Rats 1.00
Association of urinary phthalate metabolite concentrations with inflammatory biomarker levels among pregnant women 0.91
Longitudinal associations and interactions of heat and metal(loid) exposure with kidney outcomes in Mexican agricultural workers 1.00
Association between objectively assessed physical activity and kidney function among female agricultural workers in hot environments in Spain 0.03
23 12.88
Long-Term Exposure to Multiple Environmental Factors and Late-Life Cognitive Decline 1.00
Prenatal Exposure to Mixtures of Nonpersistent Endocrine-Disrupting Chemicals and Angiogenic Biomarkers, Placental Function, and Fetal Growth 0.05
Is There an Optimal Wavelength for Germicidal Ultraviolet Air Disinfection? 0.92
Prenatal Exposure to Primary Aromatic Amines: Structure-Dependent Transplacental Transfer Mechanism and Toxicity 0.17
Beyond Nephrotoxicity: Maternal–Fetal Transfer of Melamine and Potential Disruption of Placental Steroid Hormones 0.10
Exposure to Quaternary Ammonium Compounds (QACs) in Assisted Living Facilities: Implications for Older Adults 1.00
Approaching a 0% False Positive Rate for PFAS Determination Leveraging Only MS1 Data 0.93
Deglycosylation Enhances the Toxicity of Plant-Derived Glycosyl Bisphenol A during Gastrointestinal Digestion 0.06
Kidney Urate Underexcretion Mediates the Relationship between Per- and Polyfluoroalkyl Substances and their Alternatives and Uric Acid Levels: Evidence from a Case–Control Study and an Animal Study 0.32
Far-UVC (222 nm) Suppresses Bacterial UV Resistance and Repair through Inhibition of DNA Repair Pathways 0.09
Prenatal Exposure to Per- and Polyfluoroalkyl Substances and Maternal Thyroid Function during Pregnancy in a Cohort with High Familial Likelihood of Autism Spectrum Disorder 1.00
Tetrabromobisphenol S (TBBPS) Causes Non-Negligible and Multigenerational Reproductive Toxicity in Zebrafish 0.09
The Susceptibility of Airborne SARS-CoV-2 to Far-UVC Irradiation 1.00
PBDE Flame Retardant Exposure Causes Neurobehavioral and Transcriptional Effects in First-Generation but Not Second-Generation Offspring Fish 1.00
Early Life PBDE Flame Retardant Exposures Cause Neurobehavioral Alterations in Fish That Persist into Adulthood and Vary by Sex and Route of Exposure 1.00
Reactivity of Viral Proteins with Free Chlorine: Structural Insights and Implications for Virus Inactivation 1.00
The Impact of UVC Light on Indoor Air Chemistry: A Modeling Study 0.44
Wavelength-Specific Biofilm Control from Internally UV-Emitting Glass Surfaces 1.00
High-Throughput Screening Identifies Bisphenol P as a Potent Cardiotoxin, Inducing Cardiotoxicity through Apoptosis and the NF-κB Pathway 0.14
Benzotriazoles and Benzothiazoles, Maternal and Neonatal Thyroid Hormones, and Childhood Growth: A Longitudinal Cohort Study 0.13
Exposures to Contemporary and Emerging Chemicals among Children Aged 2 to 4 Years in the United States Environmental Influences on the Child Health Outcome (ECHO) Cohort 1.00
Multiphase OH Oxidation of Bisphenols: Chemical Transformation and Persistence in the Environment 0.20
Enhanced Phytopathogen Biofilm Control in the Soybean Phyllosphere by the Phoresy of Bacteriophages Hitchhiking on Biocontrol Bacteria 0.25
9 4.22
Optimal serum potassium concentrations in heart failure: an individual patient data meta-analysis 0.44
Volume vs intensity of physical activity and risk of cardiovascular and non-cardiovascular chronic diseases 0.04
C-reactive protein and cardiovascular risk in the general population 0.17
Frailty and long-term outcomes in younger patients with acute myocardial infarction 0.23
Artificial intelligence-enabled electrocardiography and echocardiography to track preclinical progression of transthyretin amyloid cardiomyopathy 0.97
Transthyretin amyloid cardiomyopathy: natural history and treatment response assessed by cardiovascular magnetic resonance 0.05
Cardiac amyloidosis detection from a single echocardiographic video clip: a novel artificial intelligence-based screening tool 0.70
Optical coherence tomography- vs angiography-guided coronary stent implantation in calcified lesions: the ILUMIEN IV trial 0.62
Predicting imminent ventricular arrhythmias from ambulatory ECG signals: far-reaching or too far to reach? 1.00
3 1.42
RESECT: A Randomised Controlled Trial of Audit and Feedback in Non–muscle-invasive Bladder Cancer Surgery 0.00
Irreversible Electroporation for Prostate Tissue Ablation in Patients with Intermediate-risk Prostate Cancer: Results from the PRESERVE Trial 1.00
Duration of Androgen Suppression with Postoperative Radiotherapy (DADSPORT) for Nonmetastatic Prostate Cancer: A Collaborative Systematic Review and Meta-analysis of Aggregate Data 0.42
18 9.94
Recommendations for the Evaluation and Management of Inflammatory Bowel Disease With Irritable Bowel Syndrome–Like Symptoms: A Joint Rome Foundation and International Organization for the Study of IBD (IOIBD) Consensus 0.62
Achalasia and risk of esophageal squamous cell carcinoma and adenocarcinoma in a multinational study 0.11
A Prospective Study of Gluten Transfer Through Kissing in Celiac-Discordant Couples 1.00
Identification of a Druggable Target That Predicts Postoperative Crohn’s Disease Recurrence 0.03
Enteric and Sympathetic Nervous System Pathways Mediate Early Life Stress Effects on Gut Motility and Pain: Mechanistic Findings With Human Correlation 0.88
Darvadstrocel in Patients With Crohn’s Disease With Complex Perianal Fistulas: The ADMIRE CD II Phase 3 Randomized Trial 0.80
Targeting APE1-Redox Function Reverses SOX9-mediated Chemoresistance in Esophageal Adenocarcinoma 0.89
The MetALD-ALD Prediction Index: A Phosphatidylethanol-Driven Biomarker Panel for Identifying Individuals With Steatotic Liver Disease and Excessive Alcohol Use 0.71
The Gut Microbiome at the Onset of Inflammatory Bowel Disease: A Systematic Review and Unified Bioinformatic Synthesis 0.04
Postoperative Ileum Transcriptomics Implicate Sex-Biased Mechanisms in Crohn’s Disease Recurrence 0.80
The ANTICIPATE-NASH Models Stratify Better the Risk of Clinical Events Than Histology in Metabolic Dysfunction-Associated Steatotic Liver Disease Patients With Advanced Chronic Liver Disease 0.18
The Prevalence and Burden of Avoidant/Restrictive Food Intake Disorder (ARFID) Symptoms in Adults with Disorders of Gut-Brain Interaction: A Population-Based Study 0.40
Implications of shame for patient reported outcomes in Bowel Disorders of Gut-Brain Interaction 0.06
Histologic response is associated with improved esophageal distensibility and symptom burden in pediatric eosinophilic esophagitis 1.00
Low FODMAP diet improves colonic barrier function and mast cell activation in patients with IBS-D: A mechanistic trial 1.00
Enhancement of Inpatient Mortality Prognostication with Machine Learning in a Prospective Global Cohort of Patients with Cirrhosis with External Validation 0.18
Peyer’s patch B cells sample transglutaminase-gluten complexes and drive celiac disease autoimmunity 0.25
Total Pancreatectomy and Islet Auto Transplant for Chronic Pancreatitis 1.00
1 1.00
PHA-4/FoxA controls the function of pharyngeal and extrapharyngeal enteric neurons in C. elegans 1.00
4 3.40
The oligogenic inheritance test GCOD detects risk genes and their interactions in congenital heart defects 0.94
Analyzing the large and complex SFARI autism cohort data using the Genotypes and Phenotypes in Families (GPF) platform 0.67
Lambdoid phages with abundant Chi recombination hotspots reflect diverse viral strategies for recombination-dependent growth 0.80
Integrated single-cell multiome analysis reveals muscle fiber-type gene regulatory circuitry modulated by endurance exercise 1.00
22 8.51
MAIT cell enrichment in Lynch syndrome is associated with immune surveillance and colorectal cancer risk 1.00
Endosomal signalling of protease-activated receptor-2 amplifies histamine-induced pain of irritable bowel syndrome 0.46
Novel insights into autoimmune gastritis: clinical profile and gastric neoplastic risk from an international multicentre study 0.20
Post-infection disorders of gut-brain interaction: results of the Rome Foundation Global Epidemiology Study 0.11
Two-step clinical care pathway to predict MASLD-related advanced fibrosis and long-term outcomes in type 2 diabetes 0.06
Targeting ADAR1-mediated RNA editing inhibits hepatic stellate cell activation and liver fibrosis by enhancing HSC-intrinsic innate immunity 1.00
Zinc-dependent RNA-binding protein controls hepatocyte senescence and recovery from alcohol-related liver failure 1.00
Targeting MLCK1 uncouples immune checkpoint inhibitor-induced colitis from antitumour immunity 0.08
TL1A-activated T cells remodel the rectal mucosa in patients with Crohn’s disease with perianal fistulising disease 0.07
Spatial transcriptomics defines the molecular progression, invasion and immune landscape of IPMN and IPMN-derived pancreatic cancer 0.21
Preclinical stages of Crohn’s disease defined by faecal calprotectin in asymptomatic first-degree relatives: screening framework for prevention trials 0.06
Autophagy of Kupffer cells modulates CD8+ T cell activation in primary biliary cholangitis 0.06
FOXM1 inhibition reduces IL-13-induced epithelial remodelling and inflammation in eosinophilic oesophagitis 1.00
Global prevalence of self-reported non-coeliac gluten and wheat sensitivity: a systematic review and meta-analysis 0.26
First genome-wide association study reveals immune-mediated aetiopathology in idiopathic achalasia 0.01
Endoscopic or surgical gastroenterostomy for malignant gastric outlet obstruction: a randomised trial 0.52
Global prevalence and gastrointestinal symptom burden of individuals with a history of cholecystectomy 0.17
Thrombospondin-2 is a performant biomarker of at-risk MASH and advanced MASH fibrosis in a large multicentre European cohort 0.03
Insulin-like peptide 5 is released in response to bile acid in the rectum and is associated with diarrhoea severity in patients with bile acid diarrhoea 0.13
Mitochondrial dysfunction drives basal cell hyperplasia in eosinophilic oesophagitis 1.00
Lifestyle factors, genetic susceptibility and risk of incident diverticulitis: an integrated analysis of four prospective cohort studies and electronic health records-linked biobank 1.00
Non-invasive risk-based surveillance of hepatocellular carcinoma in patients with metabolic dysfunction-associated steatotic liver disease 0.08
25 13.57
Efficacy and safety of belapectin for the prevention of esophageal varices in patients with MASH cirrhosis: The randomized, placebo-controlled NAVIGATE trial. 0.85
Toxic lipid-induced epigenetic activation of ICAM1 in liver sinusoidal endothelium regulates myeloid-driven fibro-inflammatory response in MASH. 0.77
OCE-205, a selective V1a receptor mixed agonist-antagonist, for the treatment of hepatorenal syndrome-acute kidney injury: A phase 2 randomized trial. 0.86
Forkhead box protein M1 network induction and crosstalk drives the development of alcohol-associated liver disease. 0.82
ECM1 produced by hepatic stellate cells serves as a gatekeeper of liver homeostasis in hepatic fibrosis. 0.05
Hepatic STEAP4 promotes liver regeneration by regulating lysosomal iron homeostasis and membrane integrity in acetaminophen-induced liver injury. 1.00
Original research: Amplification of genetic and metabolic factors in alpha-1 antitrypsin deficiency. 0.06
Real-world impact of AUD pharmacotherapy on healthcare utilization, cost, and cost-effectiveness in the United States. 1.00
Head-to-head comparison between vibration-controlled transient elastography and histology in predicting liver-related events due to metabolic dysfunction-associated steatotic liver disease. 0.08
Pruritus is common in primary sclerosing cholangitis, persists over time, and its intensity is associated with disease severity. 0.27
HBV induces liver fibrosis through the generation of reactive oxygen species in a pyruvate-dependent manner. 0.31
Predictors of fibrosis, clinical events and mortality in MASLD: Data from the Global-MASLD study. 0.42
Semaglutide therapy for metabolic dysfunction-associated steatohepatitis: November 2025 updates to AASLD Practice Guidance. 1.00
Endothelial-to-mesenchymal transition: A targetable mechanism that contributes to portal vein thrombosis in cirrhosis. 0.05
Sex and body size disparities under MELD 3.0: Evaluation of persisting gaps in liver transplant access. 1.00
Global performance of non-invasive tests in MASLD: Insights from the G-MASLD study. 0.43
Association between longitudinal weight change and clinical outcome in individuals with MASLD. 0.07
Point-of-care ultrasound (POCUS)-guided volume management and the effect of cirrhotic cardiomyopathy on acute kidney injury outcomes in cirrhosis. 0.11
Natural history and development of a novel composite endpoint in patients with alcohol-associated Hepatitis: Data from a prospective multicenter study. 0.94
Use of liver stiffness measurement for hepatocellular carcinoma risk stratification in metabolic dysfunction associated steatotic liver disease. 1.00
Pilot trials of oral betaine in participants with non-alcoholic fatty liver disease and elevated alanine aminotransferase. 0.54
Salivary microbiome and serum metabolomics add to clinical biomarkers to predict 6-month hospitalizations in a multi-center cirrhosis outpatient cohort. 0.79
Prognostic significance of mild ascites in patients with cirrhosis. 1.00
Antibody response to microbiota antigens is associated with alcohol-related liver disease severity and predicts mortality. 0.13
Dissecting liver inflammation ecosystem identifies annexin A1 as a pro-resolving target for liver failure. 0.04
2 1.30
Universal preimplantation genetic testing for monogenic disease (Karyomapping): diagnosis of amp;gt;1000 unique disorders with no detected misdiagnoses 0.30
Blastocyst segmental aneuploidy breakpoints are highly correlated with human genome fragile sites 1.00
1 1.00
Towards Autonomous Robotic Electrosurgery via Thermal Imaging 1.00
19 14.86
A longitudinal atlas of human psoriatic skin reveals the mechanisms of anti-IL-23 therapy in disrupting the type 17 inflammatory circuit 0.95
Dietary sulfur amino acids enhance anti-tumor immunity in colon cancer via an NKT cell-XCL1-cDC1 circuit 0.94
Intestinal dysbiosis exacerbates skin inflammation via microbial metabolite-driven Th2 cell differentiation 0.10
Skin inflammation and itch response are independently regulated by distinct nociceptor subsets 0.12
Germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques 0.94
Multiplexed antigen panel analysis identifies B cell phenotype and receptor genetic contributions to antibody breadth 0.93
Genetically diverse influenza antibodies highlight the role of IG germline gene variation and inform population-comprehensive vaccine strategies 0.44
Multiomic analysis of ART-interruption cohorts identifies cell-extrinsic and -intrinsic mechanisms driving lymphocyte-mediated control of HIV rebound 0.85
HIV broadly neutralizing antibody escape dynamics drive the outcome of AAV-vectored immunotherapy in humanized mice 1.00
Sensory neuron production of substance P and TAFA4 promotes disease tolerance during viral infection 0.06
Local antibody feedback enforces a checkpoint on affinity maturation in the germinal center and promotes epitope spreading 0.98
Innate lymphoid cells activated by the cytokine TL1A link colitis to emergency granulopoiesis and the recruitment of tumor-promoting neutrophils 0.78
Commensal-derived trehalose monocorynomycolate triggers γδ T cell-driven protective ocular barrier immunity 1.00
Highly functional and prolonged germinal center T follicular helper cell responses are associated with enhanced neutralizing antibody development 1.00
A myeloid Tet2-IL-1β axis modulates intestinal inflammation by restricting catecholaminergic stimulation of enterochromaffin cell differentiation 0.93
S. aureus exposure during cutaneous antigen sensitization causes basophil- and interleukin-4-dependent exaggerated food anaphylaxis 0.91
Multi-scaled transcriptomics of chronically inflamed nasal epithelium reveals immune-epithelial dynamics and tissue remodeling in nasal polyp formation 0.92
Naturalized immune responses are stable over years in a colony of laboratory mice with wild-derived microbiota 1.00
ILC3s sense gut microbiota through STING to initiate immune tolerance 1.00
3 1.93
Human Transthyretin with a Tailored Gd(III) Complex as a High-Relaxivity MRI Contrast Agent 0.33
Chemical Control of Aggregation-Induced Enhancement via β-Galactose and Gadolinium Chelates 0.60
Controlling the Kinetic and Electrochemical Properties of EuII–Containing Complexes Using Peripheral Charges 1.00
9 2.21
Acute-phase reactants as predictors of chronic kidney disease incidence in Africans: the population-based prospective RODAM cohort study 0.10
New-onset diabetes following SARS-CoV-2 infection in the Omicron era: a matched cohort study 0.03
Impact of intermittent preventive treatment of malaria in pregnancy with sulfadoxine–pyrimethamine on sexually transmitted and reproductive tract infections: results from a randomized trial in Uganda 0.44
Impacts of the COVID-19 pandemic on Brazilian families: a countrywide population-based survey 0.25
A countrywide study on post-COVID-19 condition in Brazil: the Epicovid 2.0 0.18
Evaluating potential associations between prior maternal yellow fever vaccination and protection against infant adverse outcomes following Zika virus antenatal exposure 0.04
Quantifying disruptions to tuberculosis case detection in Brazilian states during the COVID-19 pandemic 0.42
School opening associated with lower test-adjusted COVID-19 case rates in children 0.50
Age and gender profiles of HIV infection burden and viraemia: novel metrics for HIV epidemic control in African populations with high antiretroviral therapy coverage 0.25
15 10.81
The impact of adjuvant anti-obesity medications on 10-year weight loss outcomes after sleeve gastrectomy 1.00
The effect of weight-loss surgery in patients with obesity on adipose tissue mesenchymal stem cells versus circulating endothelial progenitor cells 0.95
The impact of slope-adjusted visit-to-visit body mass index variability on early dementia risk prediction 0.04
The Physiology Of the WEight Reduced State (POWERS) study: strategies for the analysis of biological specimens 0.98
Estimating the effect of hypothetical dietary protein interventions on changes in body composition of postmenopausal women over 3 years using data from the Women’s Health Initiative (WHI) Study: an emulated target trial 0.79
Sex-specific longitudinal associations between repeatedly measured movement behaviours and adiposity measures in school-aged children: a compositional data analysis approach 0.03
Is lower extremity joint replacement surgery associated with weight loss? An institutional retrospective study of 36,993 cases 0.78
Long-term change in body composition following intentional weight loss and its effect on physical function 1.00
Long-term impact of newly-proposed clinical obesity on autoimmune disease incidence: insights from the UK Biobank 0.33
Serum S100β and neuron-specific enolase correlate with obesity parameters in Mexican children 0.13
Ototoxic impacts of adipose-derived extracts on a murine auditory cell line: molecular insights from proteomic analyses 1.00
Characterizing the effect of bariatric surgery on circulating S100A9 1.00
Predictive markers of obesity and glucose metabolism dysfunction in adult common marmosets (Callithrix jacchus) 1.00
The influence of physical activity intensity on bone mineral density and trabecular bone score in young adults with overweight and obesity 0.78
Multi-modal neo-adjuvant anti-obesity medications may be more effective than medically supervised weight loss or GLP-1 therapy alone in preparing BMI≥70 patients for metabolic surgery 1.00
18 14.34
Medication Management Among Older Adults Living Alone With Cognitive Impairment. 1.00
An Artificial Intelligence-Enabled Cardiopulmonary Resuscitation Instructor. 1.00
Testosterone Treatment in Prostate Cancer Survivors With Hypogonadism 1.00
Prompt and Intensive Antiviral Chemoprophylaxis in Nursing Home Influenza Outbreaks 1.00
Extended-Release vs Sublingual Buprenorphine in Pregnancy Through 12 Months Post Partum 1.00
Automated Screening and Education for Women With Urinary Incontinence in Primary Care 1.00
Oral Semaglutide and Heart Failure Outcomes in Persons With Type 2 Diabetes 0.26
High-Dose vs Standard-Dose Influenza Vaccine in Older Adults With Diabetes 0.08
Collaborative Care for Opioid Use Disorder and Mental Illness 1.00
Antibiotic De-Escalation in Adults Hospitalized for Community-Onset Sepsis 1.00
Medical Cannabis and Opioid Receipt Among Adults With Chronic Pain 0.92
Community Health Worker Support for Hispanic and Latino Individuals Receiving Hemodialysis 1.00
Effectiveness and Cost-Effectiveness of Automated External Defibrillators in Private Homes 0.06
Remote Bone Health Service for Osteoporosis Screening in High-Risk Men 1.00
Prophylactic Antibiotics for Upper Gastrointestinal Bleeding in Patients With Cirrhosis 0.55
Proactive Telehealth-Based Sepsis Transition and Recovery Support, Hospital Readmission, and Mortality 1.00
Clinical Decision Support System for Primary Care of Opioid Use Disorder 1.00
Transfusion Strategy Effect on Quality of Life in Patients With Myocardial Infarction and Anemia 0.47
19 15.89
Children Present or Witnessing Violent Deaths and Suicides 1.00
Risk and Protective Factors Associated With HIV-Related Mortality in Children Receiving Antiretroviral Therapy 0.83
Reducing Stress After Trauma in Physically Injured Children 1.00
Chronotherapeutic Approaches to Target Insufficient and Late Sleep in Adolescents 1.00
HIV Preexposure Prophylaxis Uptake Among US Youth in a National Claims Database 1.00
Parent-Reported Chronic Pain in Children With and Without Developmental Disabilities 0.20
Sleep Health Dimensions From Wearables and Transdiagnostic Mental Health in Young Adolescents 1.00
EEG-Guided Anesthesia for the Prevention of Emergence Delirium in Children 0.22
Clinical Signs Associated With Mortality and Sepsis in Young Infants 0.88
Artificial Intelligence Length-of-Stay Forecasting and Pediatric Surgical Capacity 1.00
Once-Weekly Navepegritide in Children With Achondroplasia 0.47
Development of an Atlas for US Pediatric Acute Care 1.00
Derivation and Validation of Predictive Models for Early Pediatric Sepsis 1.00
Reevaluating Nonoperative Management for Pediatric Uncomplicated Acute Appendicitis 0.29
Gonorrhea and Chlamydia Screening for Adolescents and Young Adults in Emergency Departments 1.00
Cost-Effectiveness of Treatment for Opioid Use Disorder in Pregnancy and Its Impact on Birth Outcomes 1.00
Opioid Timeliness in the Emergency Department and Hospitalizations for Acute Sickle Cell Pain 1.00
Optimal Dose of Intranasal Midazolam for Procedural Sedation in Children 1.00
Firearm Laws and Pediatric Mortality in the US 1.00
27 15.47
Antipsychotic Efficacy and Safety of LB-102 in the Treatment of Adults With Acute Schizophrenia 0.85
Prior Trial Effects on Working Memory in Schizophrenia, Bipolar Disorder, and Healthy Control Individuals 1.00
Dementia in Severe Schizophrenia 1.00
Mirtazapine for Methamphetamine Use Disorder 0.02
Methylphenidate Treatment and Risk of Psychotic Disorder 0.20
Clozapine After 1 Failed Antipsychotic Drug Trial in First-Episode Psychosis 0.14
Health Plan Disenrollment and Mortality After Initiation of Medications for Opioid Use Disorder 1.00
Mapping ADHD Heterogeneity and Biotypes by Topological Deviations in Morphometric Similarity Networks 0.25
Spirituality and Harmful or Hazardous Alcohol and Other Drug Use 1.00
Efficacy and Safety of the Neuroplastogen TSND-201 for the Treatment of PTSD 1.00
One-Year Actigraphy Study of Sleep and Rest-Activity Rhythms as Markers of Relapse in Depression 0.06
Mental Disorders as a Risk Factor of Acute Coronary Syndrome 0.08
Yoga for Opioid Withdrawal and Autonomic Regulation 0.13
Processing Speed Impairment in Schizophrenia 1.00
Contrasting Risk Profiles for Suicide Attempt and Suicide Using Danish Registers and Genetic Data. 0.12
Pragmatic Comparative Effectiveness of Primary Care Treatments for Posttraumatic Stress Disorder 1.00
Brief Cognitive Behavioral Therapy for Suicidal Military Personnel and Veterans 1.00
Heart Rate Variability Biofeedback for Substance Use Disorder 1.00
Measures of General Intelligence and Risk for Alcohol Use Disorder 0.43
Regional Specificity of Cortical Layer 3 Dendritic Spine Deficits in Schizophrenia 1.00
Occurrence of Psychosis and Bipolar Disorder in Individuals With Attention-Deficit/Hyperactivity Disorder Treated With Stimulants 0.02
Collaborative Care for Opioid Use Disorder in Primary Care 1.00
Profiles of Genetic Risks for Psychotic Disorders 0.25
Esketamine Monotherapy in Adults With Treatment-Resistant Depression 0.91
Polygenic Risk, Psychopathology, and Personalized Functional Brain Network Topography in Adolescence 0.94
Increased Prescribing of Attention-Deficit/Hyperactivity Disorder Medication and Real-World Outcomes Over Time 0.05
Framework for Brain-Derived Dimensions of Psychopathology 0.03
39 34.49
Glycemic Control and Diabetes Outcomes After Surgical Therapy for Diabetic Gastroparesis 1.00
Portal-Venous Hypothermic Oxygenated Perfusion for Liver Transplant 1.00
Implementation and Effectiveness of an Enhanced Recovery Protocol for Children Undergoing Surgery 1.00
Surgical Approach and Long-Term Operative Recurrence Following Groin Hernia Repair 1.00
Sex Differences in Arterial Grafting in Patients Undergoing Dialysis and Coronary Artery Bypass Grafting 1.00
Veterans Hospitals vs Non-Veterans Centers in the Prevention of Limb Loss 1.00
Evolving Inguinal Hernia Repair Practice at the Veterans Health Administration 1.00
Firearm Mortality and Equitable Access to Trauma Care in Chicago 1.00
Severe Splenic Injuries in Patients With Multiple Trauma 0.70
Contemporary Outcomes of Cholecystectomy 1.00
Emergency Medical Individual Clinician Volume and Mortality in Trauma Patients 1.00
Development and Internal Validation of a Pretransplant Biomarker Panel for Mortality Prediction Following Liver Transplant 1.00
Delayed Diagnosis of Anastomotic Leak and Failure to Rescue After Colon Resection 1.00
Postoperative Sleep Dynamics Across Surgical Risk Using Wearable Device Technology 1.00
Bed Capacity and Utilization at Hospitals With Trauma Centers 1.00
Molecular Analysis of Mixed-Type and Branch-Duct Intraductal Papillary Mucinous Neoplasms 1.00
Recurrence in Patients With Lymph Node-Negative Pancreatic Neuroendocrine Tumors 0.94
Perioperative Use of Tranexamic Acid in General Surgery 0.14
Data and the Art of Surgical Preference Card Maintenance 1.00
Neighborhood Deprivation, State Laws, and Firearm Injury in the US 1.00
Preoperative Hemoglobin A1C, Glycemic Status, and Postoperative Outcomes in General Surgery 0.46
Postmarket Surveillance of Mesh Performance After Inguinal Hernia Repair 1.00
Long-Term Risk of Mesh Infection Requiring Removal After Elective Ventral Hernia Repair 1.00
Non–β-Lactam Antibiotic Use, β-Lactam Allergy, and Surgical Site Infections 1.00
Child and Adolescent Firearm-Related Homicide Occurring at Home 1.00
Obesity Treatment With Bariatric Surgery vs GLP-1 Receptor Agonists 0.80
Postoperative Pulmonary Complications in Conventional Laparoscopic vs Robot-Assisted Abdominal Surgery 0.09
Diagnostic Accuracy of Imaging in Assessing Nonviability of Disappearing Colorectal Liver Metastasis 0.11
Dexmedetomidine for Analgesia in Nonintubated Patients With Traumatic Rib Fractures 1.00
Acute Normovolemic Hemodilution in Adult Cardiac Surgery 1.00
Use of Glucagon-Like Peptide-1 Agonists Among Individuals Undergoing Bariatric Surgery in the US 1.00
Generating a New CPT Code Set for Adult and Pediatric Appendectomy 1.00
Standardized Perioperative Protocols and Variance in Pediatric Surgery 1.00
Global Scaling of a Surgical Infection Prevention Program to 5 Low-Resource Countries 0.24
Reoperation for Chronic Postoperative Inguinal Pain 1.00
Near-Infrared Autofluorescence for Parathyroid Detection During Endocrine Neck Surgery 1.00
Applying Large Language Models for Surgical Case Length Prediction 1.00
Allocation Out of Sequence in Lung Transplant 1.00
Peer and Patient Feedback to Increase Adherence to Postoperative Opioid Prescribing Guidelines 1.00
22 16.33
Symptom-Based Dosing for Neonatal Opioid Withdrawal 1.00
Fast Antimicrobial Susceptibility Testing for Gram-Negative Bacteremia 0.83
Amoxicillin-Clavulanate vs Amoxicillin for Acute Sinusitis in Adults 1.00
Intrawound Tobramycin Plus Vancomycin to Prevent Surgical Site Infection in Tibial Fractures 1.00
National Estimates of Pediatric Sepsis in US Hospitals Using Clinical Data 1.00
Treatment for Brain Metastases With Stereotactic Radiation vs Hippocampal-Avoidance Whole Brain Radiation 1.00
Emergency Department–Initiated Buprenorphine for Opioid Use Disorder 0.97
Oral Nalbuphine in Idiopathic Pulmonary Fibrosis–Associated Cough 0.25
Minor Papillotomy for Treatment of Idiopathic Acute Pancreatitis With Pancreas Divisum 0.94
Acetaminophen (Paracetamol) or Opioid Analgesia Added to Ibuprofen for Children’s Musculoskeletal Injury 0.08
Spinal Manipulation and Clinician-Supported Biopsychosocial Self-Management for Acute Back Pain 1.00
Prediction of Bacteremia and Bacterial Meningitis Among Febrile Infants Aged 28 Days or Younger 0.20
Liberal or Restrictive Postoperative Transfusion in Patients at High Cardiac Risk 1.00
A Conservative Dialysis Strategy and Kidney Function Recovery in Dialysis-Requiring Acute Kidney Injury 1.00
Discordance in Creatinine- and Cystatin C–Based eGFR and Clinical Outcomes 0.52
Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score 0.14
Semaglutide and Tirzepatide in Patients With Heart Failure With Preserved Ejection Fraction 0.69
Bivalent RSV Prefusion F Protein–Based Vaccine for Preventing Cardiovascular Hospitalizations in Older Adults 0.25
RSV Vaccine Effectiveness Against Hospitalization Among US Adults Aged 60 Years or Older During 2 Seasons 1.00
Dalbavancin for Treatment of Staphylococcus aureus Bacteremia 0.96
Structured vs Self-Guided Multidomain Lifestyle Interventions for Global Cognitive Function 0.97
Lorundrostat in Participants With Uncontrolled Hypertension and Treatment-Resistant Hypertension 0.54
33 27.35
Cell type-specific expression and subcellular localization of the human insulin upstream open reading frame (INSU) protein in pancreatic β-cells 1.00
The Multiple Sclerosis Drug Fingolimod Induces Pore-Like Membrane Defects, Contributing to Its Antimicrobial Activity 1.00
The Ion Channel, CFTR, assembles with HIPPO pathway proteins TAZ and YAP in polycystic kidney disease 1.00
Alpha-cell glucagon is essential for maintaining β-cell function and identity in adult mice 1.00
INAAC: An affinity chromatography strategy enabling characterization and quantification of influenza neuraminidase antigens in vaccines 0.78
Molecular analysis of a new patient COX15 mutation provides insight into the etiology of fatal infantile cardioencephalopathy 1.00
PIEZO1 variants that reduce open channel probability are associated with familial osteoarthritis 1.00
The butyrate-producing Gram-positive human gut bacterium, Hoskinsella mucinilytica, selectively targets host mucin N-acetylhexosamines 0.73
Dynamic assessment of the allocation of copper to cytochrome c oxidase using size-exclusion chromatography (SEC) combined with inductively coupled plasma mass spectrometry (ICP-MS) 0.97
A-type lamins anchor emerin at the inner nuclear membrane via two independent binding sites 1.00
Loss of ATM causes R-loop–associated transcriptional dysregulation and attenuates the related response to DNA damage 1.00
Deregulated translation of the transcription factor Myt3 predisposes islet β cells to dysfunction under obesity-induced metabolic stress 1.00
A luminescent reporter assay to quantify SORL1 ectodomain shedding and Retromer-dependent endosome recycling activity 0.31
Molecular impacts of Meier–Gorlin syndrome mutations on human origin licensing 1.00
Nanobodies against Clostridioides difficile CDTb provide a toolkit for potent toxin neutralization and highly sensitive quantitation 1.00
Enhanced lysosomal activity prevents infection with PrPSc and the seeding activity of α-synuclein & tau prions 0.87
Glyoxalase 1 is a proadipogenic gene 1.00
Lipopolysaccharide-Induced Cytokine Signaling Activates a Temporal Innate Defense Program and Represses Pancreatic β-Cell Identity 1.00
Compartmentalized thymidine phosphorylation by mitochondrial nucleotide kinases TK2 and CMPK2 0.93
Dominant-negative NARS1 R534∗ mutation causes wild-type subunit poisoning and heterodimer predominance in cells 0.56
A biophysical and molecular characterization of the interaction between the Alzheimer risk factor BIN1 and the neuronal scaffold protein p140Cap 0.90
Pharmacologic stimulation of insulin granule acidification increases β-cell zinc content and augments β-cell-targeted drug delivery 1.00
Nootropic benzothiazoles promote dendritic spine formation by targeting fascin-1 0.88
Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells 1.00
Association of protein arginine deiminase 4 with the myosin-9 motor complex 1.00
Functional analysis of amino acid substitutions within human AGT1 in a cell-based platform to support the diagnosis of primary hyperoxaluria type 1 0.20
Leber's hereditary optic neuropathy–associated ND1 3733G>C mutation ameliorates the mitochondrial quality control and cellular homeostasis 0.07
PTH stimulation of Rankl transcription is regulated by SIK2 and 3 and mediated by CRTC2 and 3 through action of protein phosphatases 1, 2, 4, and 5 0.86
Extensive citrullination of human serum albumin is physiological and not inherently immunogenic in rheumatoid arthritis 1.00
Characterization of ADAMTS9 proteoglycanase activity: Comparison with ADAMTS1, ADAMTS4, and ADAMTS5 0.20
Evidence against efficient spontaneous disassembly of prions into small oligomers 1.00
CryoEM structure of Rv2531c reveals cofactor-induced tetramer–dimer transition in a tuberculin amino acid decarboxylase 1.00
Nrf2-and p53-inducible REDD2/DDiT4L/Rtp801L confers pancreatic β-cell dysfunction, leading to glucose intolerance in high-fat diet-fed mice 0.10
68 60.27
Evaluating the Utility of Staphylococcus aureus Nasal Screening in Preventing Surgical Site Infections in Elective Orthopaedic Surgery: A Propensity-Matched Analysis. 0.75
Lower Trapezius Transfer at the Time of Reverse Shoulder Arthroplasty with an Allograft-Prosthetic Composite Can Restore External Rotation. 1.00
Glucocorticoid-Enhanced Fascial Plane and Peripheral Nerve Blocks Versus Periarticular and Local Infiltration Analgesia in Total Hip Arthroplasty: A Prospective Randomized Controlled Trial. 1.00
A Fracture Healing Odyssey: Kinematic Comparison of Unions and Nonunions in Human Lower-Extremity Long Bones Treated with Intramedullary Nailing: A Retrospective Cohort Study. 1.00
Development of a Radiographic Scoring System to Estimate Acetabular Protrusion Risk in Patients with Osteolytic Periacetabular Metastases. 1.00
Effectiveness of Intraosseous Morphine for Pain Control in Total Knee Arthroplasty: A Double-Blinded, Randomized Trial. 1.00
Technology Assistance Mitigates the Volume-Dependent Risk of Hip Dislocation Following Total Hip Arthroplasty. 1.00
Survivorship of Femoroacetabular Impingement Surgery at Mean 10-Year Follow-up: A Prospective, Multicenter Cohort Study. 0.89
Intraoperative Bone-Quality Assessments Are Reliable Compared with Opportunistic CT-Based Hounsfield Unit Measurements. 1.00
Surprisingly Low Rates of Aseptic Loosening in 575 Rotating-Hinge Total Knee Arthroplasties. 1.00
One-Stage Versus Two-Stage Exchange Arthroplasty for Periprosthetic Joint Infection: A Prospective Randomized Trial. 0.90
Clinical Outcomes Following Open Tibial Fractures in Latin America: A Multicenter Prospective Study. 0.36
Greater Valgus Alignment in Pediatric and Adolescent Patients with a Primary ACL Tear Compared with Healthy Controls. 1.00
Pain Outcomes Following Modern External Ring Fixation Compared with Internal Fixation for Severe Open Tibial Fractures: A Secondary Analysis of a Prospective Randomized Trial (FIXIT). 1.00
Results of a Novel Osteotome System for Femoral Stem Extraction in Revision Total Hip Arthroplasty 1.00
Predictive Factors for Fast Healing Following Surgery for Knee Osteochondritis Dissecans. 1.00
Compensatory Load Sharing by Residual Rotator Cuff Subregions Preserves Glenohumeral Mechanics in Partial and Massive Tears. 0.63
Femoral Head Perfusion Varies Widely Following Surgical Reduction for Infantile Developmental Dysplasia of the Hip: Preliminary Findings from a Prospective Study of Contrast-Enhanced Ultrasound. 1.00
Autoclaving Effectively Sterilizes Contaminated Retained Cement in Orthopaedic Surgical Trays. 1.00
Decreased Robot-Related Complications Following the Development and Adoption of a Standardized Safety Protocol 1.00
The Prevalence of Subtalar Arthritis Following Pilon Fractures. 0.97
Fluoroscopy-Guided Lateral Tibial Plateau Fracture Fixation with and without Needle Arthroscopy: A Biomechanical and Reduction-Quality Comparison. 1.00
Thigh Muscle Changes in the ACL-Deficient Knee: A 4-Year Longitudinal MRI Study of 1,207 Patients. 0.80
Physical Activity and 4-Year Radiographic Medial Joint Space Loss in Knee Osteoarthritis: A Joint Model Analysis. 0.18
Bracing Outcomes and Risk of Curve Progression in Adolescents with Idiopathic Scoliosis and Autism Spectrum Disorder. 1.00
Infection and Nonunion Rates in Open Fractures 0.73
Incidence, Characteristics, and Management of Concomitant Ipsilateral Upper-Extremity Fractures in Pediatric Monteggia Fracture-Dislocations: A 13-Year Single-Institution Case Series. 1.00
The Ultrasound-Assisted Patellar Glide Test: A Novel Examination Method for Quantifying Patellar Instability 1.00
Risk Factors for Nonunion Following Lateral Locked Plating of Distal Femoral Fractures 0.75
Five-Year Radiographic and Clinical Outcomes of Pyrocarbon Hemiarthroplasty for Glenohumeral Arthritis and Osteonecrosis. 1.00
Postoperative Abstinence Restores Osseointegration Impaired by Ethanol Consumption in a Murine Tibial Implant Model. 0.80
Helical Blade Versus Lag Screw Fixation in the Cephalomedullary Nailing of Geriatric Hip Fractures. 1.00
Debridement of Unstable Chondral Lesions During Arthroscopic Partial Meniscectomy Provides No Long-Term Benefit: Patient Outcomes 9 Years After the Original ChAMP Trial. 1.00
Quantifying Changes in 3D Acetabular Morphology in Normal Hips Based on the Development of Secondary Ossification Centers. 1.00
The Broken Wing Sign: A New Clinical Test to Detect Gluteus Medius Pathology with and without Fatty Infiltration. 0.90
Mean Body Mass Index Does Not Increase or Decrease at 10 Years After Primary Total Hip or Knee Arthroplasty. 1.00
Pediatric Spine Frailty Index Predicts Morbidity and Mortality Following Spinal Deformity Surgery. 1.00
Assessment of the Mechanical Performance of an Affordable External Fixator (AEFIX) Designed for Resource-Limited Settings. 0.97
Distinct 3-Dimensional Morphologies of Arthritic Knee Anatomy Exist: CT-Based Phenotyping Offers Outlier Detection in Total Knee Arthroplasty. 1.00
Impact of Childhood Obesity on Capital Femoral Epiphysis Morphology: A Large-Scale, Automated 3D-CT Study and Potential Implications for SCFE Pathogenesis. 1.00
Weight Loss Before Total Knee Arthroplasty Was Not Associated with Decreased Postoperative Risks. 1.00
Cement Mantle Screws in Periprosthetic Hip Fracture Fixation Near Well-Fixed Femoral Stems May Not Impact Short-Term Femoral Stem Survivorship. 1.00
From Asymptomatic Flatfoot to Progressive Collapsing Foot Deformity: Peritalar Subluxation Is the Main Driver of Symptoms. 1.00
PROMIS and ODI Tools: Clinically Useful Markers of Abnormal MRI Findings in Pediatric Patients with Back Pain. 1.00
A Unifying Radiographic Description of Legg-Calvé-Perthes Disease at Skeletal Maturity: The Head, Acetabulum, Trochanter Classification. 1.00
Coronal and Sagittal Balance Following Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis. 1.00
Bupivacaine-Meloxicam Extended-Release Solution Compared with a Standard Periarticular Injection in Primary Total Knee Arthroplasty: A Randomized Clinical Trial Showing Similar Efficacy in Postoperative Analgesia. 1.00
Ten-Year Outcomes of Hip Arthroscopy for the Treatment of FAI and Labral Tears in Patients with a Workers' Compensation Claim. 1.00
The Timing of Direct Oral Anticoagulant Usage Did Not Impact Outcomes Following Hip Arthroplasty for Femoral Neck Fractures. 1.00
Orthopaedic Manifestations in Hypermobile Ehlers-Danlos Syndrome. 1.00
Incidence and Prediction of Postoperative Urinary Retention Following Lumbar Decompression. 1.00
A Multicenter Study of Intertrochanteric and Pertrochanteric Fragility Fractures: Spanning Fixation Mitigates the Risk of Peri-Implant Fractures. 1.00
A Prospective, Randomized Comparison of Functional Bracing and Spica Casting for Femoral Fractures Showed Equivalent Early Outcomes. 1.00
Differences in Orthopaedic Surgeon Merit-based Incentive Payment System (MIPS) Performance, Demographics, and Patient Populations Based on Patient Social Risk. 1.00
High Failure Rates of Polyethylene Glenoid Components in Stemless Anatomic Total Shoulder Arthroplasty for Primary and Secondary OA. 0.07
The T4-L1-Hip Axis Objectifies the Roussouly Classification Using Continuous Measures. 0.64
The Cost-Effectiveness of Continuous Pressure Measurement in the Diagnosis of Acute Compartment Syndrome. 0.50
Comparing the in Vitro Efficacy of Commonly Used Surgical Irrigants for the Treatment of Implant-Associated Infections. 1.00
Measurement of Value in Uncomplicated Total Knee Arthroplasty: Patient-Level and Provider-Level Value Analyses of a 1-Year Episode of Care. 1.00
Outcomes Associated with Choice of Prophylactic Antibiotics in Open Fractures 0.80
Deep Infections After Open and Closed Fractures 0.80
Higher Reoperation Rates in Planned, Staged Treatment of Open Fractures Compared with Fix-and-Close 0.92
Chlorhexidine Gluconate Bathing Has Limited Ability to Prevent Surgical Site Infection Following Operative Fixation of Extremity and Pelvic Fractures 0.82
Performance of the OTA-OFC3 Classification System for Open Fractures 0.92
Alcohol-Based Versus Aqueous Skin Antisepsis Before Surgical Fixation of Open Fractures 0.40
Differences in Practice Patterns in the Use of Temporary External Fixation for the Management of Open Lower-Extremity Fractures 0.91
Local Antibiotics and the Risk of Antimicrobial Resistance in Extremity Fractures Complicated by Fracture-Related Infection 0.82
A Deep Learning-Based Clinical Classification System for the Differential Diagnosis of Hip Prosthesis Failures Using Radiographs: A Multicenter Study. 0.07
2 2.00
The cytoskeleton contributes to abnormal genome–lamina interactions in LMNA-deficient cardiomyocytes 1.00
An ethanol-induced loss of the lipid droplet–associated segregase VCP/p97 leads to hepatic steatosis 1.00
63 44.83
A phase II basket trial of vosoritide in children with RASopathies, ACAN, and NPR2 deficiency 1.00
Real-world effectiveness of burosumab across age groups: X-linked hypophosphatemia (XLH) Disease Monitoring Program 0.58
Real-world impact of treatment on growth in children with X-linked hypophosphatemia 0.31
Initial disease severity and methimazole titration for Graves' disease: a retrospective longitudinal cohort study 1.00
Associations of endocrine disrupting chemicals with anogenital distance across infancy 1.00
Antifracture Efficacy of 5- or 10-Yearly Zoledronate in Women Aged 50 to 60 Years: Secondary Analyses of a Randomized Trial 0.05
Cognitive assessment in patients with primary aldosteronism vs patients with mild autonomous cortisol secretion 0.92
International real-world study on osilodrostat efficacy and safety in adrenal Cushing syndrome 0.10
Comparing surrogate indexes for insulin resistance as predictors of type 2 diabetes 1.00
Timeliness of antiresorptive consolidation after anabolic therapy for primary fracture prevention: A US cohort study 1.00
Genotype-phenotype heterogeneity among patients with lipodystrophy harboring rare POLD1 variants 1.00
High normal parathyroid hormone and cardiovascular and total mortality: sex and age disparities in the ELSA-Brasil study 0.13
The use of semaglutide as an add-on therapy in patients with latent autoimmune diabetes in adults 0.03
Associations between radioactive iodine treatment for hyperthyroidism and cancer incidence and mortality 1.00
Severity of MASH activity by iron-corrected MRI predicts insulin resistance and cardiometabolic risk in type 2 diabetes 0.92
Natural history of pituitary incidentalomas in pediatric patients: a single-center, retrospective analysis 1.00
Weight loss reduces intermuscular adipose tissue and liver fat compared to exercise: implications for muscle quality and metabolic health 1.00
Heart ventricular function in hospitalized patients with severe hypothyroidism and myxedema coma 0.72
Therapeutic Plasma Exchange in Severe Thyrotoxicosis: Clinical Observations From a Case Series 1.00
<atl>Expanding the clinical tumor phenotype of the iEPAS1/i -asssociated tumor syndrome</atl> 0.21
Radiological Surveillance for Pituitary Adenomas in Multiple Endocrine Neoplasia Type 1: A Longitudinal Cohort Study 1.00
Implementation of a Spanish-Language, Direct-to-Patient Primary Aldosteronism Testing Program 0.87
Patient-Reported Outcomes in Palopegteriparatide-Treated Adults with Hypoparathyroidism: PaTH Forward Trial Extension 0.56
Secukinumab in Moderate-to-Severe Graves Orbitopathy: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study 0.09
Impact of Growth Hormone on Skeletal Muscle Strength, Power, Endurance, and Agility in Prepubertal Boys With Short Stature 1.00
Prospective Assessment of Mood and Quality of Life in Cushing syndrome before and after Biochemical Control 1.00
Metformin Blunts Vascular Insulin Sensitivity After Exercise Training in Adults at Risk for Metabolic Syndrome 1.00
Effect of Vosoritide therapy on IGF-I and Endogenous C-type Natriuretic Peptide in Hypochondroplasia 0.78
MECP2 Rare Variants in Boys With Central Precocious Puberty 0.69
Rapid and Sustained Response of Biochemically Uncontrolled Acromegaly to Once-Daily Oral Paltusotine Treatment 0.50
Immune Checkpoint Inhibitor Therapy for Aggressive Pituitary Neuroendocrine Tumors 0.94
The Relation Between Systemic Inflammation and the Menopause Transition: The Study of Women's Health Across the Nation 1.00
Autoimmune Thyroid Diseases and Microscopic Colitis: A Nationwide Matched Case–Control Study in Sweden 0.17
Adult Growth Hormone Deficiency, Replacement Therapy, and Outcomes in Long-Term Childhood Cancer Survivors 0.94
Handgrip Strength and Trajectories of Preclinical Obesity Progression: A Multistate Model Analysis Using the UK Biobank 0.33
Rates and Pattern of Antifracture Drug Use in 6475 Adults and Children With Osteogenesis Imperfecta 0.89
Osilodrostat-associated Adrenal Gland Shrinkage: A Case Series of Patients With ACTH-dependent Cushing's Syndrome 1.00
Clinical and Biochemical Phenotype Across the Genotypic Spectrum of 21-Hydroxylase Deficiency in 457 Individuals 1.00
The Importance of Disease Specific Growth Charts for Children with Congenital Adrenal Hyperplasia 1.00
Sleep Disturbances in Patients With Cushing Syndrome and Mild Autonomous Cortisol Secretion: A Cross-sectional Study 1.00
Association of IGF-1 levels with height from childhood to adulthood: An observational and Mendelian randomization study 0.07
Functional Domain Mapping of TPO: Insights from Six Variants in Sudanese Kindreds with Congenital Hypothyroidism 0.88
Adverse outcomes in patients with hypothyroidism undergoing bariatric surgery: A retrospective study using TriNetX 0.72
Cortisol Testing to Diagnose Adrenal Insufficiency Following Adrenalectomy for Mild Autonomous Cortisol Secretion 1.00
Association Between Testosterone Replacement Therapy and Prostatic Disorders in Elderly Hypogonadal Men 1.00
Longitudinal Characterization and Sonographic Staging of Testicular Adrenal Rest Tumors 1.00
Trends In Reported Outcomes for Growth Hormone Therapy In Children With Growth Hormone Deficiency 0.20
Facial Analysis in Acromegaly Using Machine Learning: Toward Earlier Diagnosis 0.08
Association of Glucose Response Shape in OGTT With Markers of Pancreatic Health and Inflammation Across Diverse Ages 1.00
Hyperglycemic Hypernatremic Hypertonic State: A Predominant HHS Subtype and Its Clinical and Diagnostic Features 1.00
Myofibrillar Protein Synthesis Rates Do not Differ With Low and High Estradiol Concentrations Across the Menstrual Cycle 0.20
Therapeutic Plasma Exchange and Changes in Calcium, Phosphate, Parathyroid Hormone, and Fibroblast Growth Factor-23 1.00
Trends of Diabetes in Youth (TrenDY) during COVID-19 across the United States 1.00
Impact of Abdominal and Thigh Intermuscular Adipose Tissue on Glucose and Cardiometabolic Risk in Adults With Obesity 0.04
Measuring Hypothyroidism Disease Control Using a TSH-based “Time-in-range” 1.00
Treatment of Hypothyroidism that Contains Liothyronine is Associated with Reduced Risk of Dementia and Mortality 0.32
Sex Hormones Mediate Intensive Lifestyle Intervention–Induced Bone Mineral Density Changes: Look AHEAD Sex Hormone Study 0.82
Integrative Machine Learning Approach for Predicting Resistance to First-Generation Receptor Ligands in Acromegaly 0.67
Genetics of Growth Hormone Deficiency: Insights from a Cohort of 203 Patients 0.01
Maturity-Onset Diabetes of the Young (MODY) in a Racially/Ethnically Diverse Pediatric Population 1.00
Maternal Thyroid Function During Pregnancy and Early Adolescent Regional Differences in Cerebral Gray Matter Morphology 0.10
Prediabetes Subgroups, Type 2 Diabetes Risk, and Differential Effects of Preventive Interventions 1.00
TSH Receptor Antibody Test Utilization Patterns from a National Reference Laboratory: TRAb, TSI, or Both? 1.00
55 43.64
Multiomic analyses delineate human neuroendocrine tumor cell states in relation to normal enteroendocrine cell ontogeny 1.00
Secreted phospholipase PLA2G5 acts as a hemolytic factor in sepsis 0.59
Skin-resident Langerhans cells drive neuropathic pain via chemokine-dependent neuron-immune communication 0.67
Overnutrition in mice impairs thyroid hormone biosynthesis and utilization, causing hypothyroidism, despite remarkable thyroidal adaptations 1.00
Variants in human CD48 lead to impaired T-cell immunity and increased inflammation 0.39
Rapid and profound decay of inducible and intact HIV genomes in early treated Thai children 0.09
Sex and ovarian hormone cycles alter effects of stimulant drugs on mouse dopaminergic signaling 0.94
Epigenetically controlled endothelial promyelocytic leukemia drives liver inflammation and fibrosis 0.09
Smac mimetic combined with eCD4-Ig reverses latency without reducing SHIV reservoirs in rhesus macaques 1.00
RNA-binding protein LARP6 coordinates hepatic stellate cell activation and liver fibrosis 0.96
MEK inhibitor Mirdametinib promotes fracture healing in osteofibrous dysplasia RASopathy 1.00
α4 Integrin blockade impairs CD8+ T cell neuroimmune surveillance following SIV infection 1.00
Distinct HIF1α and HIF2α functions control skeletal muscle metabolism and erythropoiesis 0.07
Immune correlates of HIV-1 rebound during broadly neutralizing antibody treatment in young children 0.66
Distinct neuronal alterations distinguish two subtypes of sporadic Creutzfeldt-Jakob disease with shared dysfunctional pathways 0.90
Variation in antiviral immunity and inflammation pathways precedes HIV-1 infection in a high-risk African cohort 0.13
A Trypanosoma cruzi trans-sialidase peptide demonstrates high serological prevalence among infected populations across endemic regions 0.96
Plasma chondroitin sulfate predicts the effectiveness of fluid resuscitation strategies in patients with sepsis 0.96
Metabolic surgery mitigates early kidney injury in obese youth with diabetes by suppressing mTORC1/JAK–STAT signaling 0.90
Boosting SIV-specific CD8+ T cell responses prior to ART interruption extends time to SIVmac239 rebound 0.90
Concomitant COX-1 and COX-2 suppression is not sufficient to induce enteropathy associated with chronic NSAID use 1.00
Dermal fibroblasts respond to IL-4 and IL-13 and promote T cell recruitment in atopic dermatitis 1.00
Higher drinking frequency corresponds to lower synaptic density in people with alcohol use disorder 1.00
Single cell characterization of the gastrointestinal HIV reservoir reveals heterogeneous cellular phenotypes 1.00
Functional Characterization of SDHB Variants Clarifies Hereditary Pheochromocytoma and Paraganglioma Risk and Genotype–Phenotype Relationships 1.00
Limiting ER-associated degradation capacity triggers acute and chronic effects on insulin biosynthesis 1.00
Secretory kinase FAM20C triggers adipocyte dysfunction inciting insulin resistance and inflammation in obesity 0.71
Selective targeting of HIV infected clones by cognate peptide stimulation and antiproliferative drugs 1.00
Stimulated thyroid hormone synthesis machinery drives thyrocyte cell death independent of ER stress 1.00
Distinct colitis-associated macrophages drive NOD2-dependent bacterial sensing and gut homeostasis 1.00
SGLT2 inhibition protects kidney function by SAM-dependent epigenetic repression of inflammatory genes under metabolic stress 1.00
Urine proteins reveal distinct coagulation and complement cascades underlying acute versus chronic lupus nephritis 0.94
Altered immune and metabolic molecular pathways drive islet cell dysfunction in human type 1 diabetes 0.42
Endothelial STING and STAT1 mediate IFN-independent effects of IL-6 in an endotoxemia-induced model of shock 1.00
Fatty acid transport protein-2 inhibition enhances glucose tolerance through α-cell-mediated GLP-1 secretion 1.00
TIE2 activation by antibody-clustered endogenous angiopoietin-2 prevents capillary loss and fibrosis in experimental kidney disease 0.14
Recessive TMEM167A variants cause neonatal diabetes, microcephaly and epilepsy syndrome 0.04
Histamine H1 receptor inverse agonists improve structure and pain in an osteoarthritis mouse model 0.75
Hypertension promotes bone loss and fragility by favoring bone resorption in mouse models 0.81
Pharmacological targeting of the IL-17/neutrophil axis attenuates calcific deposits in rat models of calciphylaxis 1.00
Divergent TIR signaling domains in TLR7 and TLR9 control opposing effects on systemic autoimmunity 0.85
An IFN/STAT1/CYBB axis defines protective plasmacytoid DC–neutrophil crosstalk in Aspergillus fumigatus–infected mice 1.00
The protein deacetylase SIRT2 exerts metabolic control over adaptive β cell proliferation 0.88
Prophage-encoded methyltransferase drives adaptation of community-acquired methicillin-resistant Staphylococcus aureus 1.00
Efficacy and safety of a therapeutic humanized FSH–blocking antibody in obesity and Alzheimer’s disease models 0.96
NFAT5 dictates crosstalk between intestinal epithelial regenerative capacity and microbiota in murine colitis models 0.08
Purinergic signaling modulates CD4+ T cells with cytotoxic potential during Trypanosoma cruzi infection 0.13
Blood immunophenotyping identifies distinct kidney histopathology and outcomes in patients with lupus nephritis 1.00
SOX2 regulates foregut squamous epithelial homeostasis and is lost during Barrett’s esophagus development 1.00
Kidney-specific WNK1 amplifies kidney tubule responsiveness to potassium via WNK body condensates 1.00
B cell deficiency induces cytotoxic memory CD8+ T cells during influenza-associated bacterial pneumonia 1.00
The macrophage-intrinsic MDA5/IRF5 axis drives HIV-1 intron-containing RNA-induced inflammatory responses 1.00
The microRNA miR-30a blocks adipose tissue fibrosis accumulation in obesity 1.00
CXCL10 secreted by SPRY1-deficient epidermal keratinocytes fuels joint inflammation in psoriatic arthritis via CD14 signaling 0.88
The tumor microenvironment of non–small cell lung cancer impairs immune cell function in people with HIV 0.86
7 5.78
Efficacy and Safety of Anselamimab in Immunoglobulin Light Chain Amyloidosis: Results From the Randomized CARES Trials 0.72
Results From the Genetic Information and Family Testing Study: A Cluster-Randomized Trial. 1.00
Alliance A222001: Oxybutynin Versus Placebo for the Treatment of Hot Flashes in Patients Receiving Androgen-Deprivation Therapy for Prostate Cancer. 1.00
New Validated Staging System for Light Chain (AL) Amyloidosis With Stage IIIC Defining Ultra-Poor Risk: AL International Staging System. 0.17
Randomized Phase II Trial of Pazopanib Versus Placebo in Patients With Advanced Extrapancreatic Neuroendocrine Tumors (Alliance A021202). 0.93
Stereotactic Radiosurgery in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases: A Multi-Institutional, Phase II, Prospective Clinical Trial. 0.96
Phase II (Alliance A091802) Randomized Trial of Avelumab Plus Cetuximab Versus Avelumab Alone in Advanced Cutaneous Squamous Cell Carcinoma. 1.00
11 10.63
Alternatively activated monocyte-derived myeloid cells promote extracellular pathogen persistence in pulmonary fungal granulomas 1.00
Inflammation rewires the enteric nervous system through neurogenic monocyte recruitment 1.00
Immune profiling links autoimmune hepatitis to human herpesvirus 6 and relaxin receptor antigens 0.93
Antibiotic use in early life impairs MAIT cell–mediated immunity in adulthood 1.00
Transcription of HIV-1 is heterogenous among authentic latent CD4+ T cell clones 0.89
Dynamics of natural and pharmacologic control of an SIV variant with an envelope trafficking defect 1.00
Salmonella-superspreader hosts require gut regulatory T cells to maintain a disease-tolerant state 0.88
Structural and genetic basis of HIV-1 envelope V2 apex recognition by rhesus broadly neutralizing antibodies 1.00
Design and characterization of HIV-1 vaccine candidates to elicit antibodies targeting multiple epitopes 1.00
Identification of a seasonal influenza vaccine–induced broadly protective neuraminidase antibody 0.94
Breast cancer gene-1 (BRCA1) potentiates maladaptive repair after kidney injury 1.00
12 4.70
Quantitative regression of qFibrosis with resmetirom: Exploratory histologic endpoints from the MAESTRO-NASH phase III clinical trial 0.55
Ammonia measurement in cirrhosis: International Delphi consensus recommendations from ISHEN 0.09
Genetic evidence that FGF21 signaling reduces problematic alcohol use and alcohol‐related liver disease 0.74
Global epidemiology of bacterial infections in patients with cirrhosis: A systematic review and meta-analysis 0.06
Longitudinal changes in cardiometabolic risk factors are associated with changes in liver stiffness in adults with MASLD 1.00
Incidence and implications of abstinence-induced recompensation in alcohol-related cirrhosis 0.04
Consensus position statements for the standardized application of histological grading and staging systems in MASH clinical trials 0.31
Prognostic value of liver stiffness measurement vs. biochemical response in primary biliary cholangitis 0.10
Reversal of ACLF and ALF using whole blood extracorporeal system combining HLA-depleted liver organoids with granulocyte-monocyte apheresis 0.24
Phase II INTEGRIS-PSC trial of bexotegrast, an αvβ6/αvβ1 integrin inhibitor, in primary sclerosing cholangitis 0.57
Effect of Hypertension on Long-term Adverse Clinical Outcomes and Liver Fibrosis Progression in MASLD 0.08
Clinical utility of phosphatidylethanol to detect underreported alcohol use and enhance steatotic liver disease subclassification 0.94
123 90.81
A New Type of Nonsuppressible Viremia Produced by HIV-Infected Macrophage 0.91
Evaluation of serum antibodies as correlates of protection against norovirus infection and disease 1.00
Initiation of Oral Pre-exposure Prophylaxis Associated With Changes in Genital Tract T Cell Phenotypes in Women Exposed to HIV 0.93
Risk Factors and Geospatial Associations With Plasmodium falciparum Malaria Infection and IgG Seroprevalence: Nigeria, 2018 0.32
Pre–Antiretroviral Therapy Vertical HIV-1 Transmission Risk in Uganda Varies by Sex of Child and Maternal Viral Subtype 0.72
Comparison of Immune Activation and Gut Barrier Dysfunction between Long COVID and HIV infection 0.90
<atl>A Genomic Analysis of Community-Associated iC. Difficile/i Infection Demonstrates Integration With National and International Strain Clusters and Limited Direct Transmission</atl> 1.00
The Natural History of Mycoplasma genitalium in the Pharynx and Rectum in a Cohort of Men Who Have Sex With Men: Prevalence, Incidence, Duration, and Symptoms 1.00
Middle East Respiratory Syndrome Coronavirus–Specific T-Cell Responses in Dromedary Camel Abattoir Workers in Nigeria Suggests Frequent Zoonotic Spillover 0.11
2024-2025 COVID-19 mRNA Vaccine Effectiveness against Severe Disease 1.00
Multiple Measles Transmission Events Associated with a Single Traveler Arriving in the United States, May 2025 1.00
Safety, tolerability, and pharmacokinetics of 6-diazo-5-oxo-L-norleucine (DON) in Malawian adults with and without malaria: a Phase I dose-escalation clinical trial 0.59
Gut Microbiota and Intestinal Monodomination as a Predictor for Bacteremia in Allogeneic Hematopoietic Cell Transplant Recipients 1.00
Addition of Clofazimine Enhances the Activity of Standard Treatment Regimen in a Mouse Model of Tuberculous Meningitis 1.00
Longitudinal symptom transitions predict incident tuberculosis risk in serial active case finding 0.43
Association of Plasma Biomarkers of Immunothrombosis With Death in Patients With Coronavirus Disease 2019 on Extracorporeal Membrane Oxygenation 1.00
Optimizing On-Demand Tenofovir Disoproxil Fumarate/Emtricitabine Dosing in Women for HIV Prevention 1.00
Immune-Based Cytokine Signatures of Prolonged Pandemic-Associated Chilblains 0.96
Molecular and Serological Evidence of Oropouche Virus Circulation in Asymptomatic Blood Donors During the 2023–2024 Outbreak in Manaus, Brazil 0.63
Variable Staphylothrombin Activity in Staphylococcus aureus Bloodstream Infections 1.00
Mitochondrial Haplogroups and Left Ventricular Diastolic Dysfunction in People Living with and without HIV 1.00
New Insights Into an Old Vaccine: Potency and Breadth of Neutralizing Antibodies Elicited by Yellow Fever Vaccine 17D Are Boosted by Heterologous Orthoflavivirus Infection 1.00
<atl>Optimized Mass Spectrometry to Uncover iM. tuberculosis/i Biomarkers in Extracellular Vesicles from Asymptomatic Tuberculosis Patients</atl> 0.43
Beyond Rifampin: Evaluating Rifapentine and Rifabutin as Alternative Treatments for TB Meningitis 1.00
Specific Biomarkers Differentiate Cerebral Malaria From Other Causes of Coma in African Children 0.50
Frailty in People with HIV is Linked to Inflammation, Bone Health, and T cell Exhaustion 0.91
Genomic Evolution of Influenza A Virus During the 2024-2025 Season, the Johns Hopkins Health System: Antigenic Drift Reduces Serum Neutralization 1.00
Limited sex-based differences in viral outcomes of ART-treated SIV/SHIV infection 1.00
Dynamics of Intact and Defective Human Immunodeficiency Virus Type 1 (HIV-1) Proviruses During Decades of Suppressive Antiretroviral Treatment in Young Adults With Perinatal HIV 1.00
High Prevalence and Genotypic Diversity of Persistent Chlamydia Trachomatis Infections Among South African Adolescent Girls and Young Women: A Tale of Two Cities 0.04
Repeat influenza vaccination effects in 2021/22 and 2022/23 in a community-based cohort in Hong Kong 0.15
Influenza vaccination effectiveness against influenza-associated hospitalization in children and the effects of repeated vaccination 0.05
Mycobacterium tuberculosis–Specific CFP-10/ESAT-6 CD4 and CD8 T-Cell Non-IFN-γ+ Responses Are Common in Young Kenyan Children Despite Low Reported Tuberculosis Exposure 0.79
Mitochondrial DNA Fragment Dynamics in Acute and Chronic Human Immunodeficiency Virus: Insights From Human and Nonhuman Primate Models 1.00
Inflammasome activation and oxidative stress in SARS-CoV-2 infection and symptomatic rebound 1.00
The Effect of a 5-Day Course of Azithromycin on Streptococcus Pneumoniae Carriage and Antimicrobial Resistance Among Kenyan Children Discharged From Hospital 0.31
Longitudinal changes in cognition and brain imaging in persons with HIV 1.00
CSF Hypo-Inflammation Drives Mortality in HIV-Associated Tuberculous Meningitis 0.45
Human Immunodeficiency Virus–Associated Proteomic Signature of Myocardial Fibrosis and Incident Heart Failure 1.00
Incidence and Severity of Postacute Sequelae of SARS-CoV-2 Infection in the Omicron Era: A Prospective Cohort Study 1.00
Estimating HIV-1 Viremic Time from Reservoir Sequence Diversity with Uncertainty Quantification 0.67
Functional and transcriptional senescence profiles of CD8+ T cells associate with the presence of carotid plaques in people living with HIV 0.06
Quantifying the role of importation on sustained malaria transmission in a low-to-moderate burden region of Southwest Uganda 0.44
A threshold in anti-EBNA-1 antibody titers distinguishes salivary EBV shedders from non-shedders 1.00
Douching Is Associated With Dysregulated Rectal Mucosal Immunity in Sexual Minority Men 1.00
Methicillin-Resistant Staphylococcus aureus Bacteremia Relapses Show Diverse Genomic Profiles but Convergence in Bacteremia-Associated Genes 0.90
Efficacies of Sequenced Monotherapies of Mycobacterium avium Lung Infection in Mouse 1.00
Weekly Oral Prophylaxis With MK-8527 Protects Rhesus Macaques From Intrarectal Challenge With Simian–Human Immunodeficiency Virus 1.00
Microbial Dominance in Diabetic Foot Osteomyelitis using Nanopore Sequencing Techniques Predicts Positive Response to Surgical Intervention 1.00
IL-4 Correlates With Bone Mineral Density in Men, and IL-4 Depletion May Drive Bone Loss in Men With HIV 1.00
Defining Severe Shigellosis in the Enterics for Global Health Study: A Comparison of Leading Diarrhea Severity Definitions Among Children With Shigella Diarrhea 0.30
Anti-neuraminidase antibody responses in older adults after consecutive vaccinations with enhanced influenza vaccines: a randomized controlled trial 0.29
Durability of the Mumps Antibody Response After the Third Dose of MMR Vaccine 1.00
Partial post-exposure protection by topical inserts containing tenofovir alafenamide fumarate/elvitegravir in a macaque model of rectal SHIV infection 1.00
Chlamydia trachomatis-specific T Cell Immunity Reflects Widespread Exposure in South African Adolescents and Young Women 0.06
Improved immune response against influenza A viruses with receipt of a recombinant influenza vaccine in healthcare personnel with prior low antibody response to egg-based influenza vaccines, Israel, 2019-20 0.73
Long-Acting Antiretroviral Therapy for Breastfeeding Women With HIV Experiencing Barriers to Adherence in Zimbabwe: Modeling Clinical Impact and Cost-effectiveness 0.61
A Phase 1 Double-Blinded Trial to Evaluate Safety, Immunogenicity, and Dosing of Measles-Vectored Chikungunya Virus Vaccine (MV-CHIK) in Healthy Adults 1.00
New Viability Assays for Acanthamoeba castellanii Trophozoites and Cysts Allow Rapid Assessment of Drug Activity 1.00
STAT1, STAT2 and T Cells Mediate Interferon-Dependent Protection Against Neurobrucellosis 0.94
<atl>Ampicillin/Sulbactam in Combination with Ceftazidime/Avibactam against Metallo-β-Lactamase-Producing Carbapenem-Resistant iAcinetobacter baumannii/i : A Genomics-Informed Mechanism-Based Model</atl> 0.77
Resistance Analysis of Low-Level Virologic Rebound During HIV-1 Treatment with Lenacapavir and Broadly Neutralizing Antibodies Teropavimab and Zinlirvimab 1.00
Estimation of prevention-effective CAB-LA concentrations among men who have sex with men (MSM) and transgender women (TGW) in HPTN 083 0.86
Adenovirus 40 and 41 antibodies associated with protection from infection in a Bangladeshi birth cohort 1.00
Childhood tuberculosis and risk of frailty in later life: evidence from a nationally representative study in Brazil 0.33
Cabotegravir and Rilpivirine concentrations and HIV-1 RNA suppression in genital fluids and rectum in people with HIV on long-acting intramuscular Cabotegravir plus Rilpivirine antiretroviral therapy 0.19
HIV Reservoir Dynamics and Bacteriome Composition Along the Gut Axis 1.00
Natural History of Nipah Virus in Hamsters: Strain, Route, and Sex-Associated Variability Characterized using Large Datasets to Inform Pre-Clinical Study Design 1.00
Resistance Analyses of Lenacapavir, Emtricitabine/Tenofovir Alafenamide and Emtricitabine/Tenofovir Disoproxil Fumarate in the PURPOSE 1 and 2 Studies 1.00
Foreign Combatants Wounded in Ukraine colonized by Extensively Drug-Resistant organisms: A Potential Source of Global Dissemination 0.50
Refined transgenic mouse models which recapitulate the natural features of chronic wasting disease with rapid prion disease onsets 1.00
Evaluating the impact of unadjusted confounding and study design on estimated pathogen-attributable diarrhea incidence among children in the MAL-ED cohort 0.80
Decreased Microbiota-Driven Tyrosine Metabolism Is Associated With Symptomatic COVID-19 in Children 1.00
A randomized phase 1 study investigating gut microbiome changes with moxifloxacin vs. oral vancomycin: Implications for iClostridioides difficile/i risk 1.00
Trichomonas vaginalis Among Cisgender Women Taking Doxycycline Postexposure Prophylaxis 0.64
A Framework for Assessing the Opportunity for Advanced Research, Development, and Regulatory Approval of Medical Countermeasures: A Component of BARDA’s Emerging Infectious Diseases Strategy 1.00
Increased plasmacytoid dendritic cells and inflammation persist in people with HIV years after tuberculosis 0.72
The Burden of Surgical Site Infections With Pathogens Presumably Resistant to Perioperative Prophylaxis in Orthopedic Tumor Surgery: Secondary Analysis of the Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY) Trial 0.20
Insights on Recurrent and Sequential iClostridioides difficile/i Infections From Genomic Surveillance in Minnesota, USA, 2019–2021 1.00
Seasonal Variation and Interspecies Dynamics Among Plasmodium falciparum and ovale Species in Bagamoyo, Tanzania 0.65
Fostemsavir Decreases the Levels of Anti-gp120 CD4-Induced Antibodies in Heavily Treatment-Experienced People With HIV 0.25
Mesenteric Ischemia and Bacterial Translocation Precipitate the Intoxication Phase of Yellow Fever 0.36
Updating the Epidemiology of Blastomycosis and Histoplasmosis in the United States, Using National Electronic Health Record Data, 2013–2023 1.00
The Source-Sink Dynamics of iPlasmodium vivax/i May Undermine Malaria Elimination Efforts in the Amazon: An Epidemiological and Population Genomic Study 0.15
Gene Editing of a Carcinogenic Liver Fluke Tetraspanin Impairs Parasite Surface Biogenesis and Extracellular Vesicle Uptake by Human Host Cells 0.25
VH3810109 Efficacy, Safety, Pharmacokinetics, and Incidence of Antidrug Antibodies in Adults With HIV-1 Naive to Antiretroviral Therapy: BANNER Study Results 0.55
c-Myc inhibits macrophage antimycobacterial response in iMycobacterium tuberculosis/i infection 0.31
Prevalence of Symptoms Associated With Long COVID Among Adolescents in the United States, Summer 2022 1.00
Epitope Conservation of AZD5148, a Broadly Neutralizing Anti-Toxin B Monoclonal Antibody, Among Diverse and Global Contemporary iClostridioides difficile/i Isolates 0.92
Virological and Immunological Outcomes of Combined Therapeutic Interventions and Dendritic Cell Therapy in People With HIV 0.31
Relative Effectiveness of High-Dose Versus Standard-Dose Influenza Vaccination Against Hospitalizations and Deaths According to Frailty Score: A Post Hoc Analysis of the DANFLU-1 Randomized Trial 0.15
Alterations of the Upper Respiratory Microbiome Among Children Living With HIV Infection in Botswana 0.53
Real-world Effectiveness of the Adjuvanted Recombinant Zoster Vaccine in ≥50-year-old Adults With Autoimmune Diseases 0.50
Emergence of ST3390: A Novel Apigmented MRSA Clone From the CC5 Lineage 1.00
Deriving Dosages for Levofloxacin Tuberculosis Preventive Treatment for Young People Exposed to Rifampicin-Resistant Tuberculosis 0.56
Influenza-associated excess mortality associated with influenza B in Hong Kong, 2014-2023 0.20
Hyperendemicity of Rift Valley Fever in Southwestern Uganda Associated With the Rapidly Evolving Lineage C Viruses 0.42
Comparability of gastrointestinal microbiome and bile acid profiles in patients with first or multiply recurrent iClostridioides difficile/i infection 1.00
Robust COVID-19 Mortality Risk Assessment: Validation of a Two-Step Algorithm from the National COVID Cohort Collaborative 1.00
Longterm kinetics of vibriocidal antibody responses after iV. cholerae/i infection in the Democratic Republic of Congo 0.95
Pneumococcal serotype distribution and coverage of existing and pipeline pneumococcal vaccines 1.00
Elimination of HIV Reservoirs Harboring Intact Proviruses 1.00
Rapid High-Sensitivity Detection of Antibodies to iTrypanosoma cruzi/i With a Recombinant Tc24 Antigen-Based Magneto-Immunoassay: A Pilot Study 1.00
Leveraging Lyme Disease Surveillance to Simulate Powassan Virus Prevalence 1.00
Antiviral Monocytes Increase Prior to Detectable HIV-1 Rebound Viremia 0.82
Structure of ClfA002 in Complex With Neutralizing Antibody AZD7745 Provides Insight into Its Broad Neutralization Mechanism in iStaphylococcus aureus/i Infection 1.00
Single-Cell Transcriptomics Reveals Depletion and Dysregulation of Mycobacterium tuberculosis–Specific Th1 and Th17 Cells Early After Acquisition of Human Immunodeficiency Virus 0.83
Global trends in antibiotic expenditure: analysis of pharmaceutical sales data, 2013 to 2023 0.48
Secreted Chorismate Mutase: A Novel Prognostic Factor in Mycobacterium intracellulare Pulmonary Disease 0.06
Influenza-Specific T-Cell Responses to Vaccination Are Independent of Underlying Hematological Malignancy: Analysis of a Randomized Influenza Vaccination Trial 0.01
Safety, Pharmacokinetics, and Acceptability of a Tenofovir Rectal Microbicide Douche Among Young Men Who Have Sex with Men: The DREAM ATN Study (ATN 163) 1.00
Long-acting Injectable Containing Lopinavir Eliminates Reliance on Ritonavir Pharmacokinetic Enhancement 1.00
Estimated US trends in SARS-CoV-2 spike antibody concentrations and correlation to risk of first-time infections based on blood donations, 2022 1.00
Evaluating the Breadth and Reliability of Influenza Vaccine Protection Indicators: A Secondary Analysis of an Animal Challenge Trial 0.89
Elevated Soluble Urokinase-Type Plasminogen Activator Receptor Levels, Organ Dysfunction, and Death in Children Hospitalized With Malaria: Considerations for Use as a Risk Stratification Tool 0.14
Priming or Boosting iPlasmodium falciparum/i Transmission-Blocking Responses With Recombinant Vaccines or Gametocyte Extract 0.77
Newly Diagnosed Individuals in Molecular HIV-1 Clusters in Rhode Island Over 3 Decades 1.00
Decrease in Incidence of Diarrhea Due to iCryptosporidium/i in Bangladeshi Children Is Associated With an Increase in Anti-iCryptosporidium/i Antibody Avidity 0.54
Mitochondrial DNA Haplogroups, Biomarkers of Inflammation and Immune Activation, and Risk of Diabetes in Veterans With and Without Human Immunodeficiency Virus 1.00
Deletion of Galectin-3 Renders Mice Less Susceptible to iCandida auris/i Skin Infection by Enhancing Antifungal Activity of Neutrophils 1.00
Reduced Metformin Concentrations in Obese Women With Human Immunodeficiency Virus Treated With Dolutegravir 0.09
Further Evidence for Plausible Transmission of Fishborne Trematodiases in the United States: Game Fish Carry Human-Infectious Trematodes and Are Eaten Raw 1.00
Using Machine Learning Algorithms to Identify Key Predictors of Invasive Mold Infection Surveillance 1.00
63 51.99
The human cerebellum encodes temporally sensitive reinforcement learning signals 1.00
5imilar Response Dynamics Represent Opposite Behaviors and Rewards in Frontal Cortex 0.88
The S1-insula Circuit Differentially Modulates Alcohol Drinking and Aversive Behavior in Mice 1.00
Primary Neural Degeneration after Cochlear Implantation: Histological and Electrophysiological Evidence from a Mouse Model 0.75
Epigenetic Repression of the Serotonergic Neuron Phenotype Following Adolescent Binge Drinking Is Restored through Inhibition of Proinflammatory Signaling by Exercise and Glycyrrhizic Acid 1.00
Motor-to-limbic design of direct synaptic communication between dopamine neurons in the midbrain 0.33
Insular input to the prelimbic cortex underlies social affective behavior in rats. 1.00
Timing, Movement, and Reward Contributions to Prefrontal and Striatal Ramping Activity 1.00
Activation by alcohol of prefrontal layer 5 pyramidal neurons depends on ascending dopaminergic input 0.88
Parallel Age-Related Cochlear Neural Degeneration and Cortical Gain Adaptation in Normal-Hearing Humans 0.11
Refinement of Nucleus Accumbens Neuronal Dynamics during Cocaine Self-Administration Training 1.00
Acceleration and Velocity Dissociate Temporal Phases of Postural Control in Rhesus Macaques 1.00
Repurposing Dexmedetomidine: Early Pharmacological Hypothermia Enhances Neuroprotection and Improves Locomotor and Bladder Functional Recovery After SCI 1.00
GABA and Glx distinctively predict motor learning and retention in young and older adults 0.33
Dopamine Dynamics in the Nucleus Accumbens Reflect Confidence in Detecting the Occurrence and Non-Occurrence of Visual Signals in Perceptual Decision-Making 0.83
Corticotropin-releasing factor and somatostatin neurons in the central amygdala mediate dynamic defensive behaviors during fear extinction 1.00
Neuronal Activity in Orbitofrontal Cortex during Trinary Choices under Risk 1.00
Causal Evidence for Prefrontal-Motor Coupling in Reward-Responsive Goal-Directed Behavior 1.00
A distinct circuit for biasing visual perceptual decisions and modulating superior colliculus activity through the mouse posterior striatum 1.00
Dopamine Supports Reward Prediction to Shape Reward-Pursuit Strategy 1.00
Distributed fMRI Patterns Coupled to Low-Frequency Cardiorespiratory Dynamics Provide Markers of Aging 1.00
Neuronal Activity Suppresses NEUROD-Dependent Transcription and Genome Organization 1.00
Neuronal features of visual attention in the mouse superior colliculus depend on learned behavioral relevance 1.00
Neurochemical and Neurophysiological Effects of Intravenous Administration of N,N-Dimethyltryptamine in Rats 1.00
Reduced Pavlovian value updating alters decision-making in sign-trackers 0.10
Domain-general neural effects of associative learning and expectations on pain and hedonic taste perception 0.47
Prefrontal default-mode network interactions with posterior hippocampus during exploration 1.00
Is the whole the sum of its parts? Neural computation of consumer bundle valuation in humans 0.67
Chemogenetic Inhibition and Optogenetic Depotentiation of the Prelimbic Cortex to Paraventricular Thalamus Pathway Attenuate Abstinence-Induced Plasticity and Heroin Seeking in Rats 1.00
The psychedelic psilocin suppresses activity of central amygdala corticotropin releasing factor receptor 1 neurons and decreases ethanol drinking in female mice 1.00
Switching between newly learned motor skills 1.00
DMT-induced shifts in criticality correlate with self-dissolution 0.13
Experience-dependent plasticity to visual sequences in mouse anterior cingulate cortex reflects familiarity 1.00
Frontoparietal Hubs Leverage Probabilistic Representations and Integrated Uncertainty to Guide Cognitive Flexibility 1.00
Identifying Key Regulators in Odorant Receptor Trafficking 1.00
Superior colliculus projections drive dopamine neuron activity and movement but not value 1.00
Noise-induced hearing loss enhances Ca2+-dependent electrical activity in lateral cochlear efferents 1.00
The Top-Down of Prefrontal Cortex to the Hippocampus Glutamatergic Pathway Regulates Reward Memory of Methamphetamine 0.07
Mediodorsal Thalamic Input to Striatum Contributes to Early Action Learning 1.00
Largely Intact But Less Reliable and Distributed Neural Representations of Subjective Value in Human Opioid Addiction 1.00
Kappa Opioid Receptors Control a Stress-Sensitive Brain Circuit and Drive Cocaine Seeking 1.00
Striatal Gradient in Value-Decay Explains Regional Differences in Dopamine Patterns and Reinforcement Learning Computations 0.50
Beta and High Gamma Oscillations in the Cortico-striatal Network Reflect Reward Certainty on a Probabilistic Reversal Learning Task 1.00
Disrupted Neurogenesis from Basal Intermediate Precursor Cells Alters the Postnatal Neocortex in the TcMAC21 Mouse Model of Down Syndrome 1.00
mWAKE in the Central Amygdala Regulates Fear Learning and Memory 1.00
Strengthening Medial Olivocochlear Feedback Reduces the Developmental Impact of Early Noise Exposure 0.22
Structural Regeneration and Functional Recovery of the Olfactory System of Adult Zebrafish Following Brain Injury 0.78
Stimulus contingency and task context encoding within the anterior cingulate-amygdala-cerebellum associative learning network 0.67
First application of a novel brain template: Motor training improves cortico-cerebellar connectivity in cerebellar ataxia 0.14
Early cortical sensitivity and speeded target selection underlie incidentally learned prioritization of visual features 1.00
Impaired Online and Enhanced Offline Motor Sequence Learning in Individuals with Parkinson's Disease 0.29
The orbitofrontal cortex underlies consolidation of Pavlovian anticipatory arousal responses in macaque monkeys 1.00
Nicotine Withdrawal Drives Aversive Behaviors by Recruiting Inhibitory Interpeduncular Nucleus Inputs to the Laterodorsal Tegmentum in Mice 1.00
Neurophysiological Evidence of Sensory Prediction Errors Driving Speech Sensorimotor Adaptation 1.00
Atypical Retinal Ganglion Cell Function in a Mouse Model of Fragile X Syndrome 1.00
Stress-sensitization of neurons in the dentate gyrus is dependent on neuronal interleukin-1 receptor signaling and is associated with increased synaptic plasticity, perineuronal nets, and excitatory/inhibitory input imbalance. 1.00
The Trembling Hand Unraveled: Motor Dynamics and Choice Inconsistency 0.07
Modulation of Dopamine Neurons Alters Behavior and Event Encoding in the Nucleus Accumbens during Pavlovian Conditioning 1.00
Neural and Behavioral Markers of Negative Symptoms and Cognitive Impairment in Patients with Psychosis 0.78
HDAC3 Serine 424 Phospho-mimic and Phospho-null Mutants Bidirectionally Modulate Long-Term Memory Formation and Synaptic Plasticity in the Adult and Aging Mouse Brain 1.00
Threonine-53 Phosphorylation of Dopamine Transporter Dictates κ-Opioid Receptor-Mediated Locomotor Suppression, Aversion, and Cocaine Reward 1.00
Oddball evoked deviant responses reflect complex context dependent expectations in mouse V1 1.00
Orbitofrontal-hippocampal state coding dynamics during reversal learning 1.00
34 25.19
Influence of sex and heart size on cardiovascular adaptations to 2 years of endurance exercise training in sedentary middle‐aged adults 0.76
In vivo quantification of mitochondrial O2 affinity in human skeletal muscle using 1H-magnetic resonance spectroscopy of deoxy-myoglobin 0.78
Restoration of neuromuscular function by mitochondrial transplantation in injured mouse skeletal muscle 1.00
Influence of age and biological sex on sweating in children exercising in warm and hot environments with comparison to adults 0.06
Maximal exercise at high altitude does not exacerbate inflammation in the human brain 0.17
Robust immune cell infiltration and macrophage senescence occur within a week of recovery after limb immobilization in older adult skeletal muscle 1.00
Regulation of basal and tumour necrosis factor α‐induced fibroblast gene expression by peptidylarginine deiminase 2 1.00
Dry and humid heat acclimation induces similar adaptations and cross‐acclimation benefits in trained male cyclists 0.17
Augmenting erythropoiesis using recombinant human erythropoietin at sea level blunts the high altitude induced increase in erythropoiesis 1.00
Translational studies of chronic supplementation with a mitochondria‐targeted antioxidant to improve physical function with ageing 1.00
Gait analysis for functional evaluation in a surgical hindlimb suspension model of muscle atrophy 1.00
Compromised synaptic signal from prefrontal cortex to mediodorsal thalamus in Alzheimer's disease models and its rescue by kinase inhibitors 1.00
Mutations in ammonia transporter RhBG that impair NH3/NH4+ transport in patients with chronic kidney disease 1.00
Intracerebral age‐independent reduction of endothelium‐dependent hyperpolarization and nitric oxide signalling in the Dp16 mouse model of Down syndrome 1.00
Kidney disease impairs tendon function in rats 1.00
On the role of descending drive and group III/IV muscle afferent feedback in modulating corticomotoneuronal excitability during knee‐extensor exercise 1.00
AltitudeOmics: Breathing variability at rest and during exercise across 16 days of acclimatization to hypobaric hypoxia 0.50
Effect of varying driving pressure and respiratory rate on ventilator‐induced lung injury in healthy and injured lungs: An experimental animal study 0.09
Role of reactive oxygen species in mediating peripheral hypoxic vasodilation and sympathoexcitation at high altitude 0.25
Endocrine and androgenic response to altitude training in professional cyclists 0.17
Physiological mechanisms underlying enhanced performance with blood flow restriction training: neuromuscular, vascular and metabolic adaptations 0.08
Exercise and hypoxia independently stimulate platelet liberation of brain‐derived neurotrophic factor and platelet factor 4 0.09
Effects of ageing on neural onset and offset responses in core and belt auditory cortex of alert macaque monkeys 1.00
PKMζ is necessary for long‐term depression and long‐term potentiation in the medial prefrontal cortex 1.00
Molecular responses in abdominal subcutaneous adipose tissue after a session of endurance exercise: effects of exercise intensity 1.00
Soft tissue accumulations of phosphate are not always associated with serum phosphate or with calcifications in mouse models of hyperphosphatemia 1.00
The influence of biological sex on the metabolic basis of skeletal muscle fatigue iin vivo/i 1.00
Enteric glial S100B controls rhythmic colonic functions by regulating excitability and specificity in gut motor neurocircuits 1.00
Effects of ageing and exercise training on cerebrovascular vasomotor reactivity, depressive behaviour and the hippocampal transcriptome 1.00
Exhaustive exercise abolishes REV‐ERB‐α circadian rhythm and shifts the kynurenine pathway to a neurotoxic profile in mice 0.07
Shared and distinct adaptations to early‐life exercise training based on inborn fitness 1.00
Passive dehydration increases oxidative stress and mTOR signalling pathway activation in young men following resistance exercise 1.00
Mitochondrial haplotype and sex modulate responses to endurance exercise training 1.00
Functional sympatholysis of neuropeptide Y‐mediated vasoconstriction in humans 1.00
34 31.21
A single center experience of 2,000 adult lung transplants 1.00
Late failure of endovascular aortic repair: Indications for and outcomes of endograft explantation 1.00
Longer Travel Distances and Ischemic Times with Ex-Vivo Lung Perfusion in the Composite Allocation Score Era – a Nationwide Analysis 1.00
Arterial graft choice and outcomes within the Veterans Administration: A 20-year review of 47,525 patients 1.00
Pulses that predict: Postoperative perfusion index and outcomes in high-risk pediatric cardiac surgery 1.00
Large Airway Bronchial Wash Lipidomics as Novel Biomarkers for Chronic Lung Allograft Dysfunction 1.00
Sex-specific outcomes after thoracic aortic surgery 0.14
Impact of normothermic regional perfusion on ex vivo lung perfusion outcomes in donation after circulatory death lung donors 0.63
Oxygen extraction trajectories during cardiopulmonary bypass impact postoperative outcomes in coronary artery bypass grafting 1.00
Association of GLP-1 Inhibitors with Cardiovascular Outcomes in Patients Undergoing Coronary Artery Bypass Surgery 1.00
A decade of reoperative adult cardiac surgery with Del Nido cardioplegia 1.00
Prolonged pulseless electrical activity warm ischemia predicts mortality and graft dysfunction in donation after circulatory death heart transplant 1.00
Long-term survival and operative outcomes of the Bentall procedure for aortic root aneurysm, aortic dissection, and endocarditis 1.00
Randomized, Sham-Controlled Trial of Intraoperative Ticagrelor Removal to Reduce Perioperative Bleeding 0.75
Venoarterial extracorporeal membrane oxygenation versus off-pump lung transplantation: Interim analysis of a prospective, randomized clinical trial 1.00
Short- and long-term outcomes of chest wall resection and reconstruction for breast cancer 1.00
Pleural Space Complications After Lung Transplantation 1.00
Minimally invasive resection of non–small cell lung cancer after chemoimmunotherapy: A multicenter study in academic hospitals 0.85
Outcomes of esophageal diversion and long-term prognosis: A single-institution experience 1.00
Improving timely transplantation while reducing cancellation of scheduled surgery 0.13
Stroke After Aortic Arch Surgery with Short Circulatory Arrest Times: The Role of Cerebral Perfusion Strategies 1.00
When the Gold Standard Fails: Propensity-Matched Comparison of Peroral Endoscopic Myotomy after Heller Myotomy vs. Index Peroral Endoscopic Myotomy 1.00
Salvage Esophageal Reconstruction with Colonic Conduit: A Single Center 25-Year Experience 1.00
Lung Transplant Outcomes After Implementation Of a Hospital-Based 10C Controlled Hypothermic Organ Preservation Unit 1.00
Bloodless Heart Transplantation in Patients Who Refuse Transfusion: An 11-Year Case Series 1.00
Three-decade evolution from open to endovascular aortic repair of late anastomotic pseudoaneurysm of the descending thoracic or thoracoabdominal aorta 1.00
Association Between Subclavian Vein Patency and Health-Related Quality of Life Outcomes Among Patients with Venous Thoracic Outlet Syndrome 0.89
Impact of the Composite Allocation Score on Racial/Ethnic Disparities in Lung Transplantation Waitlist Outcomes 1.00
Redo Coronary Artery Bypass Grafting in Patients with Patent Bilateral Internal Thoracic Artery Grafts: Exceptions to a Lifetime Warranty 1.00
Tissue perfusion pressure: A novel hemodynamic measure to assess risk of acute kidney injury after cardiac surgery 1.00
Long-Term Outcomes of Diaphragmatic Relaxing Incisions during Challenging Primary and Revisional Hiatal Reconstruction: A Propensity-Matched Analysis 1.00
Predicting and Diagnosing Pneumonia in Patients Undergoing Elective Cardiac Surgery via Machine Learning Analysis of Exhaled Volatile Carbonyl Compounds 1.00
2022: Perioperative and critical care year in review for the cardiothoracic surgery team 1.00
Diagnostic Effectiveness and Safety of Robotic-Assisted Bronchoscopy for Subsolid Pulmonary Nodules – A Multicenter, Prospective, Observational Study 0.83
7 3.98
Adolescents’ Relationships With Their Parents and Peers as Mediators Between Economic Circumstances and Emotional Symptoms: A Multicountry Longitudinal Analysis 0.05
Examining Features of Atypical Depression in Youth From the Texas Youth Depression and Suicide Research Network Research Registry 0.92
Attention-Deficit/Hyperactivity Disorder Subtypes Defined by Cognition Have a Distinct Neural and Clinical Profile and Differ in Response to Atomoxetine 0.40
Structural Brain Correlates of Childhood Inhibited Temperament: An ENIGMA-Anxiety Mega-Analysis 0.60
Waves of Change: A Nationwide Analysis of Acute Pediatric Healthcare Encounters Attributed to Substance Use Before, During, and Following the COVID-19 Pandemic 1.00
Preadolescent Benefits of Parent-Child Interaction Therapy Emotion Development for Preschool Depression: 4 Year Follow Up 1.00
Exploring the Behavioral and Emotional Manifestation of Polygenic Risk for Psychiatric Disorders Among Schoolchildren 0.01
39 28.65
Prognostic determinants of early and late relapse in cutaneous squamous cell carcinoma: a multicenter retrospective cohort study 0.78
Perioperative Management in Nail Surgery: An International Delphi Consensus Statement 0.15
Analysis of Medicolegal Precedents of Neuromodulators and Soft-Tissue Fillers 2008-2025 0.46
Efficacy and Safety of Ruxolitinib Cream in Patients With Lichen Sclerosus: Results From a Phase 2, Randomized, Double-Blind, Vehicle-Controlled Study 1.00
Development of a Core Outcome Set for Clinical Trials in Melasma 0.90
Topical vs Systemic Corticosteroids for DRESS Syndrome: Real-World Outcomes from a Multi-Center Retrospective Cohort 1.00
Hydroxychloroquine Use and 5-Year Cardiometabolic Profile and Cardiovascular Risk in Isolated Discoid Lupus Erythematosus: A Retrospective Cohort Study 1.00
Disparities of itch severity in outpatient clinics as measured by the ItchyQuant 1.00
Topical combined 5-fluorouracil and calcipotriene for actinic keratosis and superficial keratinocyte carcinoma: Modified Delphi expert panel guidelines from ITSCC 0.88
Impact of early treatment of psoriasis on disease recurrence—Results from the STEPIn study 0.13
The 487-gene expression profile test guides systemic therapy selection to improve outcomes for patients with atopic dermatitis: Results from a prospective trial 1.00
Cartilage grafts for alar reconstruction in nasolabial interpolation flap surgery may negatively affect breathing function and cosmesis: A retrospective study 1.00
Tumor necrosis alpha inhibitor therapy is associated with increased long-term risk of nonmelanoma skin cancer and melanoma: A retrospective cohort study 1.00
Efficacy and safety of sodium-glucose cotransporter-2 inhibitors in patients with psoriasis and comorbid type 2 diabetes: A population-based target trial emulation 1.00
Hyperkalemia incidence in females over 45 years old on spironolactone for dermatologic conditions: A retrospective cohort study 1.00
Safety and tolerability of combination oral spironolactone and low-dose oral minoxidil for hair loss in adult females: A retrospective cohort study 1.00
To test or not to test? Revisiting the value of baseline screening and monitoring tests among biologic treatments for psoriasis using an evidence-based assessment 1.00
Efficacy of Dupilumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus: An Open-Label, Single-Arm, Exploratory Study 1.00
Bimekizumab demonstrated a favorable safety profile and high levels of efficacy with up to 2 years of treatment in patients with moderate to severe hidradenitis suppurativa: Pooled results from two phase 3 randomized, controlled trials and their open-label extension 0.32
Joint Position Statement from the National Psoriasis Foundation Medical Board and the International Psoriasis Council on Routine Testing for Latent Tuberculosis Infection Prior To and During Treatment of Psoriasis Patients with IL-17 or IL-23 Inhibitors 0.72
Efficacy and Safety of Ruxolitinib Cream in Patients With Mild to Moderate Hidradenitis Suppurativa: Results From a Randomized, Double-Blind, Vehicle-Controlled Phase 2 Study 0.80
Ultraviolet induced fluorescent dermoscopy for the diagnosis of skin tumors: A multicenter study 0.15
Clinical Practice Guidelines for the Management of Basal Cell Carcinoma in Gorlin Syndrome 0.98
Prevalence, incidence, and risk factors for dermatologic conditions in people with HIV in the modern antiretroviral era: A cohort study in Washington, DC 1.00
Examining the Impact of Child Atopic Dermatitis on Maternal Depression: A Longitudinal Cohort Study 1.00
A randomized, double-blind, placebo-controlled phase 2 study of eltrekibart, a novel septa-specific monoclonal antibody to CXCR1/2 ligands, in adults with hidradenitis suppurativa 1.00
Efficacy and Safety of Cosibelimab in Advanced Cutaneous Squamous Cell Carcinoma: Results From a Pivotal Open-label Study With a Median Follow-up of ≥2 Years 0.17
Impact of Immunosuppression on Cutaneous Squamous Cell Carcinoma Outcomes 0.88
Comparative risk of reactivation of hepatitis B and C after treatment with biologics and targeted synthetic DMARDs in psoriasis and psoriatic arthritis: a 15-year multicenter cohort study 0.02
Real-world treatment patterns in patients with generalized pustular psoriasis (GPP): 0.43
Efficacy and Safety of Ruxolitinib Cream for the Treatment of Moderate to Severe Chronic Hand Eczema: Results From a 16-Week, Multicenter, Randomized, Double-Blind Study 0.67
Establishment of standardized definitions and a core set of outcome characteristics following hidradenitis suppurativa surgery developed by an expert Delphi consensus 0.55
Chronic skin conditions and life trajectories: development and validation of “Dermatology Long-Term Life Impact Measure (DLLIM)” 0.15
Disparities in Survival and Tumor Characteristics in Patients With Single and Multiple Primary Merkel Cell Carcinomas 0.11
The Effect of Isotretinoin Treatment for Acne Vulgaris on Height in Adolescents: A Retrospective Cohort Study Using the Rochester Epidemiology Project 1.00
Systemic risk profiles of topical ruxolitinib and oral Janus kinase inhibitors in patients with atopic dermatitis: A retrospective cohort study from the TriNetX network 1.00
Type 2 Immunity Links Eczematous and Lichenoid Eruptions Caused by Immune Checkpoint Inhibitors 1.00
Diagnosis and Management of Yellow Nail Syndrome: An International Multi-Institutional Retrospective Cohort Study of 111 Cases by an Expert Panel 0.47
Satellitosis/in-transit metastasis in cutaneous squamous cell carcinoma: Risk factors and the prognostic significance 0.93
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Accelerating Proton Exchange in 1,8-Bis(dialkylamino)naphthalene Proton Sponges through Intramolecular Catalysis for CEST MRI 0.64
Cryo-Structural Insights into Enzymatic Peptide Self-Assembly Driving Extrinsic Lytic Cell Death 1.00
A Small Molecule That Inhibits the Quorum Sensing Receptor AgrC in Staphylococcus aureus 1.00
Structure-Guided Semisynthesis of Blasticidin S–Amicetin Chimeras as Selective Ribosome Inhibitors 1.00
PGLa and Magainin 2 Can Porate Membranes via Transient Hourglass-Shaped Toroidal Pores 0.57
Potent Racemic Antimicrobial Polypeptides Uncovered by a Stereochemical Series of Cationic d/l Backbones 1.00
Deciphering Ibogaine’s Matrix Pharmacology: Multiple Transporter Modulation at Serotonin Synapses 0.91
DNA Modulates Structural Transitions and Oligomerization Kinetics of the Functional Amyloid CRES 1.00
Actifensin Evolution in the Human Oral Cavity over the Past 100,000 Years 0.04
Distinct Target Site of Lenacapavir in Immature HIV-1 and Concurrent Binding with the Maturation Inhibitor Bevirimat 1.00
Chemical Synthesis of Oligosaccharides Derived from Streptococcus Pneumoniae Serotype 35B and D Provides Molecular Insight in l-Ficolin Binding 0.52
Macrocyclic Phage Display for Identification of Selective Protease Substrates 0.75
Eggerthella lenta Produces a Cryptic Pro-inflammatory Lipid 1.00
Insights into the Mechanisms of Small Molecule-Induced Agonism and Antagonism of a Quorum Sensing Receptor in Pseudomonas aeruginosa 1.00
Chemotype- and Target-Driven Genome Mining for a New Natural Product Inhibitor of Bacterial Peptide Deformylase 1.00
ATP-Ion Complexation and Lithium’s Bioactive Form in Cellular Solutions 1.00
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Mechanical Thrombectomy and Catheter-Directed Thrombolysis in Acute Pulmonary Embolism 1.00
Association of Autonomic Dysfunction With Long COVID Evaluation Using Quantitative Autonomic Testing 1.00
High-Dose vs Standard-Dose Influenza Vaccine in Chronic Kidney Disease The DANFLU-2 Trial Subgroup Analysis 0.09
Risk of Hyperkalemia With Empagliflozin, Finerenone, or Both: Secondary Analysis of CONFIDENCE Randomized Trial 0.60
Myocardial Amyloid Burden in Transthyretin Amyloidosis 0.12
Frailty Scale Captures Multidimensional Vulnerability and Predicts Mortality in Heart Failure 0.03
Effect of Acoramidis on Recurrent and Cumulative Cardiovascular Outcomes in ATTR-CM: Exploratory Analysis from ATTRibute-CM 0.77
Timing of Mortality Benefit in Outcomes Trials in Transthyretin Amyloidosis 0.71
Influence of Type 2 Diabetes on the Effects of Tirzepatide in Patients With Heart Failure and a Preserved Ejection Fraction With Obesity A Prespecified Stratification-Based Analysis 0.95
Adiposity-Related Anthropometrics and Clinical Outcomes in Heart Failure With Mildly Reduced or Preserved Ejection Fraction A Participant-Level Pooled Analysis of Randomized Clinical Trials 0.65
Outcomes of Percutaneous Mechanical Aspiration in Right-Sided Infective Endocarditis A Multicenter Registry 1.00
Using Compression Stockings to Prevent Recurrence of Vasovagal Syncope A Randomized Sham-Controlled Trial 0.03
Impact of Vutrisiran on Cardiac Biomarkers in Patients With Transthyretin Amyloidosis With Cardiomyopathy From HELIOS-B 0.41
Effects of Vutrisiran on Cardiac Function and Outcomes in Patients With Transthyretin Amyloidosis With Cardiomyopathy 0.69
Relation Between the Incidence of In-Hospital Cardiac Arrest and Survival in Older Patients 1.00
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Cognitive Trajectories After Major Surgery in Older Adults and Factors Associated With Severe Decline 1.00
Feasibility of a Multicomponent Frailty Intervention During Post‐Acute Rehabilitation in Skilled Nursing Facilities 1.00
Glycemic Control and Utilization Risk With the Conversion of Glimepiride to Glipizide in Adults 64 Years and Older at an Integrated Health Care System 1.00
Involvement of Patients With Cognitive Impairment and Care Partners in Advance Care Planning Decision‐Making: A Qualitative Study 1.00
Exploring Current Emergency Medical Services Approaches to Manage Agitated Older Adult Patients: An Analysis of Statewide Protocols 1.00
The Association Between Hospital Harms and 1‐Year Mortality Following a Hip Fracture in Ontario, Canada: A Cohort Study 0.05
The Effect of an Early Cognitive Intervention on Global Cognition in Older Hospitalized Adults With Delirium 1.00
Transdermal Buprenorphine for Pain Management in Older Patients With Multiple Rib Fractures 1.00
Patient and Clinician Perspectives on Chronic Pain Communication in Advanced Kidney Disease 1.00
Two Brief Steps, Better Foresight: Cognitive Screening and Adverse Outcomes in Older Adults Admitted From the Emergency Department 0.42
Primary Care Practitioners' Approaches to Deprescribing Opioids for Older Adults With Chronic Pain: A Qualitative Analysis 1.00
The Bright Side of Life: Optimism and Risk of Dementia 0.93
Association of Geriatric Emergency Department Care With Hospitalization and Mortality in Older Adults 1.00
Burden and Risk Factors of CGM-Detected Hypoglycemia in Older Adults With Type 2 Diabetes 1.00
Barriers to the Implementation of Local Anesthesia for Older Adults Undergoing Inguinal Hernia Repair 1.00
Naturalistic Driving Outcomes and Sensorimotor Function in Cognitively Normal Older Adults 0.97
Association Between Different Analgesic Use and Hypertension Among Medicare Beneficiaries With Osteoarthritis 1.00
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<atl>Variation in Psychotropic and Non‐Psychotropic Prescribing in Nursing Homes: A Multi‐Level scpEMR/scp ‐Based Retrospective Cohort Study</atl> 0.05
Long‐Term Outcomes Associated With Peripheral Nerve Blocks for Hip Fracture Surgery: A Retrospective Comparison of Medicare Data 1.00
European Working Group on Sarcopenia in Older People Algorithm: Step‐by‐Step Relation With Length of Hospitalization 0.13
Surgical Stabilization of Rib Fractures in Geriatric Trauma Patients: A National Trauma Data Bank Review 1.00
Association of Geriatric Consult Services With Geriatric Processes of Care and Clinical Outcomes in US Trauma Centers 0.95
Older Age Is Associated With Long‐Term Retention in Buprenorphine Treatment for Opioid Use Disorder 1.00
Impact of the 2015 Dutch Long‐Term Care Reform on Nursing Home Use and Access for People With Dementia 0.25
“By the Skin of Our Teeth”: U.S. Hospital, Regional, and State Experiences of Scarcity During the COVID-19 Pandemic 0.94
The Role of Brain Structure in Explaining Physical Functioning in Male Veterans With Impaired Kidney Function 1.00
Sensorimotor Impairment and Incident Dementia in the US Medicare Beneficiaries 1.00
Perceived Pain Following Hypnotic Deprescribing in Older Adults 1.00
Increase in Fall-Related Fatalities in the Home Following the COVID-19 Pandemic Onset 1.00
Disseminating Acute Care for Elders Principles in a Geriatric Observation Unit: Preliminary Data 1.00
A Health Communication Strategy to Promote Dementia Risk Reduction: The CULTIVAMENTE Pragmatic Cluster-Randomized Trial 0.12
A Peer Support Intervention for Black Family Caregivers of Persons Living With Dementia: A Feasibility Study 1.00
Functional Decline and Loss of Independence After Traumatic Injury in Older Adults With Dementia 1.00
Perioperative Optimization of Frail Older Adults Undergoing Elective Colorectal Surgery 1.00
What Matters Most to People Living With Dementia and Their Care Partners During Emergency Department Visits 1.00
Capacity for and Utilization of Dual‐Energy X‐Ray Absorptiometry Within the Veterans Health Administration 1.00
Leading Cause of Death and Life Expectancy Among US Superagers 1.00
Predictors of a Gabapentinoid–Loop‐Diuretic Prescribing Cascade in U.S. Nursing Home Residents 1.00
The Changing Landscape of the Providers of Home‐Based Medical Care in Traditional Medicare 1.00
Trends in Initiation of Buprenorphine for Opioid Use Disorder Among Older Adults 1.00
Association Between Herpes Zoster and Risk of Incident Fragility Fractures in scpUS/scp Veterans: A Matched Cohort Study 0.53
Role and Expectations of Family Caregivers in Hospital at Home in the scpUS/scp and Canada 1.00
Association Between Frailty and Patients' Experience of Cancer Treatment and Care 0.25
scpSGLT2/scp Inhibitors in Older Adults With Cardiovascular Disease: A Systematic Review and Meta‐Analysis 0.46
A Qualitative Study of Health Priorities of People With Dementia and Care Partners in Emergency Department and Hospital Care in a Public Safety‐Net Setting 1.00
Caregiver Emotional Wellbeing Is Related to Nursing Home Admissions Among Veterans 1.00
scpCAPABLE/scp for People After Hospitalization: A Randomized Trial 1.00
Patients With Dementia Undergoing High‐Risk Inpatient Surgery Have Poor Outcomes 1.00
Safety of Baclofen and Tizanidine in Older Adults: A Retrospective Cohort Study in a Large Integrated Health Care System 1.00
Physical Resilience After Hip Fracture: Unpacking the Roles of Resistance and Recovery 0.30
Caregiving Network Characteristics and Mental Health Care Utilization by Older Adults 1.00
Communication Surrounding Treatment Preferences for Older Adults With Dementia During Emergency Medical Services Response 0.95
Age-Related Changes in the Clinical Picture of Long COVID 1.00
Patterns of Benzodiazepines and Hypnotic Drugs Dispensing After Hip Fracture Among Older scpUS/scp Adults Previously on the Drugs 1.00
Arthritis and Functional Limitations Among Home Healthcare Aides: 2021–2023, Behavioral Risk Factor Surveillance System 1.00
Information and Counseling Gaps on Perioperative Neurocognitive Disorders Among Older Adults 1.00
Can an Innovative Physical Therapy Program Improve Executive Function? A Study Among Veterans With Slow Gait Speed 1.00
Improving Osteoporosis Clinic Access With Nurse‐Led Telephone Call for Veterans on Bisphosphonates 1.00
Impact of Concern About Falling on Physical and Social Activities of Older Adults With Hypertension 1.00
Antipsychotic Use and Successful Discharge Rates in Heart Failure‐Related Hospitalizations 1.00
Under Documentation of Anemia in Older Ambulatory Patients 1.00
Does Cannabis Use Reduce Symptoms of Depression, Anxiety, Pain, and Insomnia Among Older Adults? A Systematic Review 1.00
Pattern and Associated Factors of Benzodiazepine Discontinuation Among Older Adults Following Hospitalization 1.00
Mitochondrial Fitness Science Communication: A Qualitative Study 1.00
Recent Innovations in Peer Programs for Socially Isolated Older Adults: Implications for Public Health Emergency Preparedness 1.00
Associations of CT Muscle Area and Density With Functional Outcomes and Mortality Across Anatomical Regions in Older Men 1.00
Nutritional Impairment and Quality of Life Trajectories Among Older Adults With Advanced Cancer 1.00
“I Don't Wake Up Completely”: Older Adults' Trade‐Offs Between Nighttime Ambulation Safety and Sleep Quality 1.00
A Multimodal Fall Prevention Intervention in the Setting of the Emergency Department 1.00
Treatment Burden Among Older Adults in the United States, 2022 1.00
Mapping the Final Journey: End‐Of‐Life Frailty Trajectories and Cause of Death 0.25
Clinician Perspectives on Increased Gabapentinoid Prescribing in Nursing Homes 1.00
Use of Nursing Homes Among Medicaid Beneficiaries Newly Diagnosed With Cancer 1.00
Data Resource Profile: The Veterans Affairs—Health and Retirement Study Aging Veteran Cohort 1.00
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Nondialyzable versus Dialyzable β -Blockers in Hemodialysis : A Target Trial Emulation Study. 1.00
Loss of Cyclin G-Associated Kinase Leads to Lysosome Dysfunction and Immune Modulation in Podocytes. 0.95
Efficacy and Safety of Atrasentan in Patients with IgA Nephropathy Receiving Sodium-Glucose Cotransporter 2 Inhibitors: Placebo-Controlled, Crossover Trial. 0.29
Discoidin Domain Receptor 1 Translocation to the Mitochondria Promotes Oxidative Stress and Apoptosis in Acute Kidney Injury. 1.00
Subclinical Primary Aldosteronism and eGFR Decline Over Time. 0.07
A HaloTag Knock-In Resource for In Vivo and In Vitro Analysis of Endogenous Polycystin-2 Localization, Turnover, and Transport. 1.00
Development and Validation of a Multivariable Prediction Model for Kidney Failure in Early Autosomal Dominant Polycystic Kidney Disease. 0.94
α-Klotho Promotes Cell Death and Suppresses Inflammation through TNF-Cellular Inhibitor of Apoptosis Protein 1 Signaling in Autosomal Dominant Polycystic Kidney Disease. 1.00
Systemic Phosphate Elevations Induce FGF23 Production in Skeletal Muscle to Reduce Renal Phosphate Reabsorption in Mice 0.93
Peritoneal Dialysis Initiation Patterns by Health Service Area during an Era of Expansion 1.00
Renal Resistance on Hypothermic Machine Perfusion and Acceptance of Deceased Donor Kidney Allografts 1.00
Ultrasound Localization Microscopy to Assess the Intrarenal Microvasculature in Autosomal Dominant Polycystic Kidney Disease 0.96
Inhibition of Interleukin-33 in Diabetic Kidney Disease 0.19
Integrin Alpha1 Beta1 Promotes Interstitial Fibrosis and Cyst Growth in a Mouse Model of Polycystic Kidney Disease​ 0.17
Matrix Stiffness Directs Early Injury and Ketogenesis Programs to Prime Kidney Repair 1.00
A Ciliary Phosphoinositide Pathway Regulates the Dosage of Polycystins in Primary Cilia 1.00
Automatically Measuring Kidney, Liver, and Cyst Volumes in Autosomal Dominant Polycystic Kidney Disease. 0.87
High Phosphate and Low Protein Mediate Arterial and Cutaneous Vascular Calcification in CKD Mice. 1.00
Accuracy of Identification of Cardiovascular Events with ICD Diagnosis Codes versus Physician Adjudication in CKD and Kidney Failure. 1.00
Metabolic Dysregulation of 27-Hydroxycholesterol Sensitizes Proximal Tubular Epithelial Cells to Ferroptosis in Ischemic Acute Kidney Injury. 0.11
Effect of Finerenone on Morbidity and Mortality in CKD. 0.38
Epidermal Growth Factor Receptor Activation Stimulates SOX9 Expression in Injured Renal Proximal Tubule Epithelial Cells. 1.00
Pyruvate Dehydrogenase and Cellular Metabolism in Calcineurin Inhibitor-Induced Kidney Fibrosis. 0.29
Enhanced Expression of the Female-Biased Gene Gsta2 in Male Proximal Tubule Cells Improves Renal Resilience to Ischemia-Reperfusion Injury. 1.00
Dysregulated Bone Marrow Contributes to Glomerular Injury through Soluble Factors. 1.00
Validation of the Klinrisk Machine Learning Model for CKD Progression in a Large Representative US Population. 0.57
Microbes and Glomerular Filtration Rate in Health and CKD in Mice. 0.83
Structured Application of Genetic Testing in a Pediatric Kidney Clinic. 1.00
KRT20 Suppresses Exosomal Secretion of PRDX2 and Ferroptosis in Acute Kidney Injury. 0.08
Effects of Dapagliflozin on Health-Related Quality of Life in Patients with CKD. 0.17
Genetic Variation and Ultrafiltration with Peritoneal Dialysis: A Genome-Wide Association Study. 0.35
Measurement, Estimation, and Correlates of the Glomerular Filtration Rate before and after Bariatric Surgery. 0.42
Higher versus Lower Phosphate Targets for Patients Undergoing In-Center Hemodialysis: A Randomized Controlled Trial. 1.00
A Multiomics Study of Circulating Proteins and Kidney Stone Risk. 0.94
Cardiac LIM Protein, Kidney Fibrosis, and Vascular Change after Acute Cardiorenal Syndrome. 0.93
Use of eGFR Slope Thresholds as End Point Components in a Kidney Disease Progression Hierarchical Composite End Point. 0.29
Kidney Parameters with Tirzepatide in Obesity with or without Type 2 Diabetes. 0.77
Obesity, Underweight, and Accuracy of eGFR Using Cystatin C and Creatinine in a Northern European Population. 0.38
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Menopausal hormone therapy and risk of liver cancer in a swedish population-based cohort study 0.17
Antidepressant adherence and breast cancer recurrence risk in women with major depressive disorder: a retrospective cohort 1.00
Quality of life and care experiences in a US multi-institutional neuroendocrine tumor cohort 1.00
Risk of fracture following androgen receptor pathway inhibitors in men with advanced prostate cancer 1.00
Opioid use after breast cancer in Denmark: a nationwide study of social and clinical factors 0.30
Subsequent breast cancer risk after benign biopsy in racially diverse women: Siteman Cancer Center 1.00
Development and validation of a risk prediction model for acute care use among older advanced cancer patients on clinical trials 1.00
Neighborhood deprivation on increasing deficit accumulation in older breast cancer survivors and non-cancer controls 1.00
FaceAge as a biomarker for prognosis and treatment stratification in large-scale oncology cohort 0.76
Liver fat and clinical outcomes in individuals with stage I-iii Colon or rectal cancer 0.08
Redefining neurocognitive outcomes after radiation for brain metastases: a patient-level meta-analysis of recovery following initial decline 1.00
Lipid biomarkers of habitual alcohol intake and associations with pancreatic cancer risk 0.94
Tattooing and risk of melanoma: a population-based case-control study in Utah 0.98
Basal cell carcinoma risk prediction in survivors of childhood cancer 0.70
Thyroid hormones and epithelial ovarian cancer risk and survival: results from the European Prospective Investigation into Cancer and Nutrition study 0.02
Stereotactic MRI Guided Adaptive Radiotherapy: a pooled analysis of a master prospective trial 1.00
Trends in the incidence of cancers related to HIV-AIDS in Harare, Zimbabwe 1990-2019 0.06
Association of opioid and benzodiazepine coprescribing with adverse events among older adults with cancer 1.00
Colon, colorectal, and all cancer incidence increase in the young due to appendix reclassification 0.83
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Therapeutic Efficacy and Antigenicity of a Novel PEGylated IgA Protease in Preclinical Models of IgA Nephropathy 0.10
A post hoc analysis of BLISS-LN found Belimumab plus mycophenolate mofetil improves kidney outcomes versus placebo plus mycophenolate mofetil in active lupus nephritis 0.44
Distinct proteomic signatures of urinary extracellular vesicles link to albuminuria and treatment responses in diabetic kidney disease 0.07
Estrogen protects female mice with chronic kidney disease from fibroblast growth factor 23-induced left ventricular hypertrophy 1.00
Insights from the BLISS-LN Phase 3 study of biomarker associations with kidney response to belimumab in lupus nephritis 0.42
Reversal of advanced diabetic kidney disease in mice treated with a monoclonal anti-VEGFR1 antibody 1.00
Clinical and Histologic Predictors of Non-Diabetic Kidney Disease in Patients with Diabetes Mellitus 1.00
Roles of WNK1 and mTORC2 in aldosterone-independent regulation of potassium secretion in the distal nephron. 0.79
Independent association between acute kidney injury and kidney function trajectory 1.00
Reduced podocyte stiffness is a feature of proteinuric kidney disease 0.13
N-propargylglycine restores survival by preventing calcium oxalate stone formation, tubular injury, and kidney dysfunction in a lethal mouse model of primary hyperoxaluria type 2 1.00
Evidence from multicenter clinical studies and humanized mouse models indicates that glomerular mesangial IgA2 deposition contributes to the pathogenesis of IgA nephropathy 0.08
Klotho in the kidney distal convolution regulates urinary Klotho excretion and kidney calcium reabsorption, but not phosphate homeostasis 0.15
A population-based, regression discontinuity analysis examined the effects of nationwide alerting for acute kidney injury on health care and patient outcomes 0.21
Endothelial prolyl hydroxylase 3 mitigates maladaptive inflammation to promote post-ischemic kidney repair 1.00
Podocyte-derived endothelin-1 and endothelial cell endothelin A receptors are essential for glomerular injury in mouse models of focal segmental glomerulosclerosis 0.94
Genotype-phenotype characteristics and disease progression of FAN1-related karyomegalic tubulointerstitial nephropathy 0.18
Population-based estimated Glomerular Filtration Rate distributions and associated health outcomes provide opportunities for early identification of and primary prevention of chronic kidney disease 0.10
Sodium-glucose co-transporter 2 inhibition improves age-dependent kidney microvascular rarefaction 0.81
Aldehyde dehydrogenase 1 A1 regulates the transcription of PD-L1 and its targeting with disulfiram together with PD-L1 immunotherapy synergistically delays cyst growth in ADPKD 1.00
Genetic screens of imaging-derived kidney volumes identify genes linked to kidney function 0.17
A randomized controlled trial evaluated the effect of pravastatin on kidney disease outcomes in adult patients with early-stage autosomal dominant polycystic kidney disease. 1.00
Inactivation of Pkd2 in adult mice results in delayed cyst formation and identifies sex as a major modifier of disease severity. 1.00
Heterogeneity in the relationships between albuminuria and glomerular structure in type 1 and type 2 diabetes. 0.57
Critical role of transcription factor SOX4 in tubular epithelial cell dedifferentiation and fibroblast activation during kidney fibrosis 1.00
The Single Cell Landscape of the Human Vein After Arteriovenous Fistula Creation and Implications for Maturation Failure 1.00
Kidney injury and colocalization of complement C3, IgA, and IgG in glomerular immune-complex deposits of patients with IgA nephropathy or IgA vasculitis with nephritis. 1.00
A stronger type I interferon signature distinguishes ANCA-associated vasculitis phenotypes and predicts kidney prognosis 0.09
The Coming of Age for Polycystic Kidney Disease 0.13
Integrated spatial and functional metabolic profiling identified the thick ascending limb as a mitochondrial vulnerability hub in acute kidney injury 0.06
Phosphoenolpyruvate carboxykinase 1-mediated cataplerosis is required to maintain mitochondrial fitness and to avoid kidney disease progression 0.19
The randomized DIALIZE-Outcomes trial evaluated sodium zirconium cyclosilicate in hemodialysis 0.64
Cellular senescence and its association with aldose reductase promote cyst growth in autosomal dominant polycystic kidney disease 1.00
Protein kinase ROCK1 activates mitochondrial fission linking to oxidative stress and muscle atrophy 0.59
The enzyme SMPDL3b in podocytes decouples proteinuria from chronic kidney disease progression in experimental Alport Syndrome 0.88
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Mesoscale Modeling of Hydrogels Under Frictional Shear Stress 1.00
Enhanced Diffusion and Retention of Proteoglycan Replacements in Cartilage through Thermoresponsive Polyelectrolytes 1.00
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Microhomology-mediated end joining acts directly on replication forks to repair single-ended double-strand breaks 0.85
Phage-encoded small RNA hijacks host replication machinery to support the phage lytic cycle 0.33
Alternative start codon selection shapes mitochondrial function and rare human diseases 1.00
Phage SSB detection by retron Eco8 msDNA unleashes nuclease-mediated immunity 1.00
A widespread family of viral sponge proteins reveals specific inhibition of nucleotide signals in anti-phage defense 0.64
FMRP drives mRNP targets into translationally silenced complexes 1.00
Microprotein SMIM26 drives oxidative metabolism via serine-responsive mitochondrial translation 0.13
76 40.71
Anxiety sensitivity and intolerance of uncertainty track distinct neurobehavioral dimensions of avoidance in anxiety-related disorders 1.00
Beyond fear circuits: multiscale neurobiological architecture of panic disorder 0.05
White matter microstructure in relatives of people with schizophrenia or bipolar disorder: an ENIGMA meta-analysis 0.24
Grin2a knockout in adolescent dopamine neurons disrupts prediction error signaling and produces a phenotype relevant to schizophrenia 1.00
Thalamo-cortical white matter connectivity-defined thalamic subarea volumes predict individual delay discounting 0.33
Polysubstance use disorders among US adults 1.00
Alzheimer’s disease-like brain pattern biomarker: capturing risks and predicting disease onset 1.00
Multiscale characterization of cortical signatures in positive and negative schizotypy: a worldwide ENIGMA study 0.11
Microglia respond to and induce anxiety and grooming in mice using calcium signaling 1.00
Multi-omics and electrophysiological examination of GABAA receptors in the dorsolateral prefrontal cortex of humans with alcohol use disorder 1.00
A prefrontal cortex-nucleus accumbens circuit attenuates cocaine-conditioned place preference memories 0.64
Local chemoarchitecture explains widespread lower cortical thickness associated with clinical high risk for psychosis 0.18
TrkB promotes the neuronal secretion of soluble Siglec-2 (CD22) to mitigate microglial activation and alleviate depression-like behaviors in male mice 0.13
A longitudinal DNA methylation atlas and its link to brain structure and mental health 0.06
Brain structural abnormalities in treatment-resistant schizophrenia 0.31
Cortical morphometry might predict currently prescribed vs. discontinued medications in bipolar disorder, even after controlling for the cumulative dose effects: An ENIGMA mega-analysis 0.13
Microbiota-Driven microglia reprogramming reverses depressive-like behaviors through Peripheral-to-Central immune crosstalk 0.10
Computational mechanisms of learning and forgetting differentiate affective and substance use disorders 1.00
Neuroanatomy reflects individual variability in impulsivity in youth 0.92
NADPH oxidase-1 suppression prolongs the antidepressant-like effect of ketamine 0.06
Elevated pre-supplementary motor area activity during reward expectancy: An impulsivity-related neural marker of vulnerability to bipolar and externalizing disorders 1.00
The dynamics of AMPA receptors underlies the efficacy of ketamine in treatment resistant patients with depression 0.02
Combining neurobiological markers and a sociodemographic risk score to predict adolescent depression – An IDEA RiSCo prospective cohort study 0.20
The global burden of mental and substance use disorders among adolescents and young adults 0.67
Biomarker for craving and acamprosate treatment response in patients with alcohol use disorder: insights from multi-omics 1.00
Trends and patterns of medical stimulant use by US adults 1.00
Gene dosage effects of 22q11.2 copy number variants on in-vivo measures of white matter axonal density and dispersion 0.74
A brain-enriched circRNA blood biomarker can predict response to SSRI antidepressants 0.56
Computational phenotypes underlying effort-based decision-making and negative symptoms in a transdiagnostic severe mental illness sample 1.00
Cross-Platform and cross-species lipidomic profiling identifies promising biomarkers for adolescent major depressive disorder 0.13
Translational reprogramming of dentate gyrus peptidergic circuitry gates antidepressant efficacy 0.09
Spatiotemporal mapping of brain organisation following the administration of 2C-B and psilocybin 0.40
Psychotropic medications and their interactions with subcortical brain volume in bipolar disorder: An ENIGMA mega-analysis 0.22
Structural brain differences associated with panic disorder: an ENIGMA-Anxiety Working Group mega-analysis of 4924 individuals worldwide 0.36
Homeostatic scaling ensures behavioural stability during corticosterone negative feedback 0.08
Prediction of postoperative delirium after cardiac surgery by the interplay between preoperative plasma p-tau181 and IL-6 and heart-brain axis related factors: results from the prospective observational study FINDERI 0.02
The serotonin 1B receptor is required for some of the behavioral effects of psilocybin in mice 1.00
Fshr gene depletion prevents recognition memory loss, fat accrual and bone loss in Alzheimer’s mice 1.00
Downregulation of integrin α3 in ADHD mirrored in mutant mouse model by dopamine-dependent hippocampal AMPAR expression 0.12
Antidepressant-like effects of extinction learning as an animal model of behavioral therapy 1.00
Structural brain abnormalities and aggression in schizophrenia: mega-analysis of data from 2095 patients and 2861 healthy controls via the ENIGMA consortium 0.20
Genetic architecture of suicidal ideation continuum: latent profile analysis of data using the million veteran program cohort 1.00
Extracellular condensates (ECs) are endogenous modulators of HIV transcription and latency reactivation 1.00
Brain morphometry, stimulation charge, and seizure duration in electroconvulsive therapy 1.00
Age-varying distinct neuroanatomy in young children with autism spectrum disorder and fragile X syndrome 0.13
The 4-alkyl chain length of 2,5-dimethoxyamphetamines differentially affects in vitro serotonin receptor actions versus in vivo psychedelic-like effects 0.40
Altered acetylcholine modulations and corticoaccumbal pathway in P11-linked social dysfunction 0.18
Regional brain morphology and current antidepressant use: findings from 32 international cohorts from the ENIGMA major depressive disorder working group 0.18
Relapse risk prediction in patients with first-episode bipolar disorder: development, external validation, and pharmacotherapy associations of a machine learning model 0.04
GRIN2A null variants confer a high risk for early-onset schizophrenia and other mental disorders and potentially enable precision therapy 0.23
Hippocampal SGK1 promotes vulnerability to depression: the role of early life adversity, stress, and genetic risk 0.54
DNA hypomethylation at specific CG-sites within TRAK1 is linked to the neurocognitive profile in Klinefelter syndrome 0.50
Development and validation of a prognostic model and risk calculator for the estimation of bipolar-spectrum disorder risk in hospitalised adolescents with non-psychotic/non-bipolar mental disorders 0.13
A low frequency damaging SORCS2 variant identified in a family with ADHD compromises receptor stability and quenches activity 0.02
Psychedelic neuroplasticity of cortical neurons lacking 5-HT2A receptors 1.00
Aging reduces motivation through decreased Bdnf expression in the ventral tegmental area 1.00
Hippocampal Cofilin and CFL1 gene variants are linked to Alcohol Use Disorder phenotypes 0.05
Genetic and epigenetic analysis of plasma glial fibrillary acidic protein (GFAP) levels in PTSD 1.00
Autophagy controls the hippocampal postsynaptic organization and affects cognition in a mouse model of Fragile X syndrome 1.00
Dopaminergic frontostriatal pathways in major depressive disorder and childhood sexual abuse: a multimodal neuroimaging investigation 1.00
GABAA receptor availability in clinical high-risk and first-episode psychosis: a [11C]Ro15-4513 positron emission tomography study 0.05
Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth 0.37
Defective Hoxb8 microglia are causative for both chronic anxiety and pathological overgrooming in mice 1.00
Projection-specific roles of basolateral amygdala Thy1 neurons in alcohol-induced place preference 1.00
A single glucocorticoid response element regulates sociability in a sex-specific manner 1.00
A study of gene expression in the living human brain 1.00
Genetic and environmental aetiologies of the transition from nonsuicidal self-injury to suicide attempt: a longitudinal twin study 0.05
Pathogenic microbiota disrupts the intact structure of cerebral organoids by altering energy metabolism 0.18
An amygdala-cortical circuit for encoding generalized fear memories 1.00
Interleukin 13 signaling modulates dopaminergic functions and nicotine reward in rodents 0.37
5-HT2C receptors in the nucleus accumbens constrain the rewarding effects of MDMA 1.00
Disease clusters and their genetic determinants following a diagnosis of depression: analyses based on a novel three-dimensional disease network approach 0.04
Targeting complement C3/C3aR pathway restores rejuvenation factor PF4 and mitigates neurocognitive impairments in age-related perioperative neurocognitive disorders 0.14
Single-cell transcriptomics reveals Sox6 positive interneurons enriched in the prefrontal cortex of female mice vulnerable to chronic social stress 0.13
Directing negative emotional states through parallel genetically-distinct basolateral amygdala pathways to ventral striatum subregions 0.96
Investigation of brain white matter and social cognition in schizophrenia and schizotypal personality disorder using neurite orientation dispersion and density imaging 1.00
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Noninvasive Optoacoustic Imaging of Oxygen Saturation Reveals Hypoxic Hematopoietic Bone Marrow during Systemic Inflammation 0.07
63 45.93
Feature-specific threat coding in lateral septum guides defensive action 1.00
White matter micro- and macrostructure brain charts for the human lifespan 1.00
Sleep chart of biological ageing clocks in middle and late life 0.81
Lineage and organ signals sequentially build organ intrinsic nervous systems 1.00
Prefrontal to ventral tegmental area dynamics drive contingency degradation 1.00
Multiplexed magnetic resonance imaging 0.55
Translation-dependent degradation of cas12 mRNA triggered by an anti-CRISPR 0.83
Vaccination generates broadly cross-neutralizing antibodies to the HIV Env apex 0.73
A spatial atlas of the healthy human liver from live donors 0.10
The DNA virome varies with human genes and environments 1.00
Insulin resistance prediction from wearables and routine blood biomarkers 0.94
Capturing dynamic phage–pathogen coevolution by clinical surveillance 0.44
B cell imprinting in children impairs antibodies to the haemagglutinin stalk 0.91
Intestinal interoceptive dysfunction drives age-associated cognitive decline 0.96
Merlin: a computed tomography vision–language foundation model and dataset 0.91
A membrane-bound nuclease directly cleaves phage DNA during genome injection 1.00
Peripheral immune-inducer dendritic cells drive early-life allergic inflammation 1.00
Dynamic antigen expression and cytotoxic T cell resistance in HIV reservoir clones 0.96
Mucosal vaccination clears Clostridioides difficile colonization 1.00
Integrase anchors viral RNA to the HIV-1 capsid interior 0.21
Striatum-wide dopamine encodes trajectory errors separated from value 1.00
Bacterial immune activation via supramolecular assembly with phage triggers 1.00
Mosquito–capsid interactions contribute to flavivirus vector specificity 0.05
Cholinergic modulation of dopamine release drives effortful behaviour 1.00
A prophage-encoded abortive infection protein preserves host and prophage spread 0.88
Common variation in meiosis genes shapes human recombination and aneuploidy 0.86
Microbiota-induced T cell plasticity enables immune-mediated tumour control 1.00
Albumin orchestrates a natural host defence mechanism against mucormycosis 0.17
Evidence accumulation from experience and observation in the cingulate cortex 0.80
Mimicking opioid analgesia in cortical pain circuits 1.00
Prevalence of Alzheimer’s disease pathology in the community 0.05
Correlates of HIV-1 control after combination immunotherapy 1.00
CD8 T cell stemness precedes post-intervention control of HIV viremia 0.88
Sustained HIV-1 remission after heterozygous CCR5Δ32 stem cell transplantation 0.03
Thalamocortical transcriptional gates coordinate memory stabilization 1.00
Building compositional tasks with shared neural subspaces 1.00
Long-read metagenomics reveals phage dynamics in the human gut microbiome 1.00
Integrator dynamics in the cortico-basal ganglia loop for flexible motor timing 0.80
Rare genetic variants confer a high risk of ADHD and implicate neuronal biology 0.23
Multi-omic profiling reveals age-related immune dynamics in healthy adults 1.00
Myocardial reprogramming by HMGN1 underlies heart defects in trisomy 21 1.00
Isolation, engineering and ecology of temperate phages from the human gut 0.05
Spatial metabolic gradients in the liver and small intestine 0.98
The astrocytic ensemble acts as a multiday trace to stabilize memory 0.03
Efferocytic remodelling of pancreatic islet macrophages by limited β-cell death 0.95
Monoclonal antibodies protect against pandrug-resistant Klebsiella pneumoniae 0.09
The Panoptes system uses decoy cyclic nucleotides to defend against phage 1.00
Dietary cysteine enhances intestinal stemness via CD8+ T cell-derived IL-22 1.00
Transitions in dynamical regime and neural mode during perceptual decisions 1.00
Cocaine chemogenetics blunts drug-seeking by synthetic physiology 0.97
A compressed hierarchy for visual form processing in the tree shrew 1.00
mAChR4 suppresses liver disease via GAP-induced antimicrobial immunity 0.83
Multiple oestradiol functions inhibit ferroptosis and acute kidney injury 0.09
Remodelling of corticostriatal axonal boutons during motor learning 1.00
Determinants of successful AAV-vectored delivery of HIV-1 bNAbs in early life 1.00
A gut sense for a microbial pattern regulates feeding 0.90
Prophages block cell surface receptors to preserve their viral progeny 0.30
Loss of FCoV-23 spike domain 0 enhances fusogenicity and entry kinetics 0.94
A mouse brain stereotaxic topographic atlas with isotropic 1-μm resolution 0.03
Engrafted nitrergic neurons derived from hPSCs improve gut dysmotility in mice 0.92
A multidimensional distributional map of future reward in dopamine neurons 0.17
Multi-timescale reinforcement learning in the brain 0.50
Ischaemic endothelial necroptosis induces haemolysis and COVID-19 angiopathy 0.10
1 1.00
Antimicrobial peptide delivery to lung as peptibody mRNA in anti-inflammatory lipids treats multidrug-resistant bacterial pneumonia 1.00
2 1.14
Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis 0.14
A SETD2–CDK1–lamin axis maintains nuclear morphology and genome stability 1.00
2 1.06
Proteolysis activity mapping and substrate discovery platform for identifying tumor-activated biosensors 1.00
Structure and mechanism of an actin-dependent bacterial phosphoryl AMPylase 0.06
422 266.78
Integration of donor microbiota following FMT correlates with anti-PD-1 response in melanoma 1.00
COXFA4L2 upregulation preserves residual cytochrome c oxidase activity in COXFA4-related Leigh-like encephalopathy 0.09
Single-phage profiling illuminates viral individuality during bacterial cell fate determination 1.00
Two hypnozoite-expressed RNA-binding proteins inhibit liver stage replication 1.00
ToxiTaRGET: a multi-omics database for toxicant-responsive molecular targets 1.00
Single nucleotide variants drive evolutionary phage-host arms race in anaerobic carbon dioxide-converting microbiome 0.30
BNT162b2 LP.8.1 early vaccine effectiveness against COVID-19 emergency department, urgent care, and outpatient visits 1.00
Muscle mitochondria, function, mass, and quality of life in prostate cancer during androgen deprivation therapy 1.00
Lifespan normative modeling of brain microstructure 0.74
Regional heterogeneity in phenotypic and genetic associations between bone and brain in humans 0.29
Long-read deep sequencing reveals high rates of multilineage transmission and rapid viral population changes in acute HIV infection 0.63
Large-scale investigation for antimicrobial activity reveals newly-identified defensive species across the healthy skin microbiome 0.74
An integrative approach for studying immunological variation in an aging population – The Milieu Intérieur follow-up study 0.03
Disinfection of hospital sink drains enriches pseudomonadota and efflux pump-mediated antibiotic resistance in reestablished biofilms 1.00
Multivalent nanobodies for potent and broad neutralization of Staphylococcus aureus toxins 0.85
TGFβ-mediated dural progenitor cell migration into the coronal suture is crucial for preventing craniosynostosis 1.00
Interpretable machine learning and signal processing for automated reading and quality control of lateral flow tests for schistosomiasis 0.13
Mpi-driven N-glycosylation orchestrates mucin O-glycosylation and intestinal homeostasis 1.00
Phage-encoded factor stimulates DNA degradation by the Hna anti-phage defense system 1.00
Clinically-applicable prediction of hospital stay and patient similarity retrieval in paediatric cardiology using machine learning 0.03
Artificial intelligence for predicting hospital admissions from the emergency department: a prospective, quasi-experimental study 1.00
Systematic multi-omic deconvolution of the clinical heterogeneity of Down syndrome 1.00
Cross-reactive human antibody responses to H5N1 influenza virus neuraminidase are shaped by immune history 1.00
Pharmacological markers of HIV prevention for oral pre-exposure prophylaxis in men who have sex with men 0.43
Biochemical and brain heterogeneity characterizes psychiatric and non-psychiatric illness 0.11
Elimination of senescent cells with senolytic drugs as adjunctive host-directed therapy reduces tuberculosis progression in mice 1.00
Early-life Wnt4 expressing colon stromal cells orchestrate lifelong mucosal homeostasis via BMP-driven iNKT cell imprinting 0.69
Human brain changes after first psilocybin use 0.18
An IL-17-DUOX2 axis controls gastrointestinal colonization by Candida albicans 0.94
A viral APOBEC3 antagonist distinguishes HHV-6A from HHV-6B 0.14
Resolving mesoscale brainstem-prefrontal-striatal pathways underlying decisions upon salient events using submillimeter-resolution fMRI 0.67
Bifidobacterium bifidum-derived nanoparticles attenuate alcoholic liver disease via enhanced hepatic phagocytosis and gastrointestinal homeostasis 0.11
RNA targeting therapy for a prenatally enriched potassium channel associated with severe childhood epilepsy and premature death 1.00
Face aging rate quantifies change in biological age to predict cancer outcomes 0.90
V- and VL-scores unveil viral signatures and origins of protein families 0.83
Acute sleep rebound following sleep restriction is associated with reduced mortality risk 0.38
Targeting insulo-frontal pathway to reduce stress-evoked cognitive rigidity 1.00
Nonergodicity and Simpson’s paradox in neurocognitive dynamics of cognitive control 1.00
Coupled cross-sectional and longitudinal non-negative matrix factorization reveals dominant brain aging trajectories in 48,949 individuals 0.89
Identification of synovial lymphatic system in the temporomandibular joint and their roles in arthritis and pain 1.00
Small RNA genomics of Aedes aegypti mosquitoes discovers infectious viruses that trigger an RNA interference response 0.72
Suppression of astrocyte BMP signaling improves molecular signatures and functional deficits in a fragile X syndrome mouse model 1.00
Spatiotemporal asymmetries on brain energy landscape uncover system entrapment related to depression severity 0.89
A pharmacokinetic and pharmacodynamic drug-drug interaction study of dorzagliatin and empagliflozin in patients with type 2 diabetes and obesity: an open-label phase I trial 0.09
Accelerating Leigh syndrome drug discovery through deep learning screening in brain organoids 0.12
Chemotherapy-induced activation of caspase-1 and IL-1α release by cancer cells remotely skews myelopoiesis to drive pro tumorigenic systemic neutrophil-dominant inflammation 1.00
Improved dynamic MRI of the wrist and heart at 0.55 T enabled by rapid 3D printed flexible coils 0.67
Multi-kingdom profiling reveals altered gut phage-bacteria-metabolite interactions in MASLD 0.13
Structural analyses uncover protease-adhesin interactions and c-di-GMP receptor regulation in sulfate-reducing bacteria 0.29
γδ T cell-stromal networks modulate matrix composition and vascularity in foreign body response 0.95
Target Trial Emulation of Vaccine Effectiveness in 5- to 17-years-olds with Prior SARS-CoV-2 Infection 1.00
Cryo-EM reveals structural variability of apolipoprotein A-I amyloid fibrils across organs, mutations, and clinical presentations 0.92
SARS-CoV-2 vaccination and infection elicit cross-neutralizing responses against clade 3 and 4 sarbecoviruses 1.00
An anti-adhesive compound modulating the production of Staphylococcus aureus cell wall-anchored proteins 0.31
N-Glycans modulate tilting of HIV-1 envelope glycoprotein 1.00
Unexpected detection of Mycobacterium tuberculosis DNA in US-born patients in putative association with clinical syndromes 0.42
Proinsulin regulators identified with CRISPR screen and in vivo mouse QTL mapping 1.00
Host–microbiome archetypes differentiate infection from pathogen carriage in the human lower airway 1.00
Multiomics characterization of acute child illness and mortality in Africa and South Asia 0.36
Structural polymorphism of ex-vivo ALECT2 amyloid fibrils revealed by cryo-EM 0.93
Sex-specific increased reactivity of the PVT and prolonged PVT→CeA circuit engagement following psilocin administration 1.00
HIV-1 uncoating location dictates sites of integration 1.00
Hemostatic Tough Adhesives seal tissue and control hemorrhage 1.00
Daily steps offset risks of sedentary behavior in the All of Us research program 1.00
A deep representation learning model to predict response to vagus nerve stimulation 0.38
Real-world evidence for comparative safety of second-line antihyperglycemic agents in older adults with type 2 diabetes 0.70
An in vivo fitness gene of Toxoplasma, MIC11, is essential for PLP1-mediated egress from host cells 0.11
Social reward outcompetes drug seeking dopaminergic ensembles to prevent relapse 0.07
Generalization of fear learning is shaped by inhibitory sensory processing in mice 1.00
Influence of the broadly neutralizing antibody VRC01 on HIV breakthrough virus populations in antibody-mediated prevention trials 0.61
Non-canonical IL‑22 receptor signaling remodels the oral mucosal barrier during Candida albicans immunosurveillance 1.00
A single viral enzyme drives tRNA-dependent hypermodification of DNA at adenine 0.70
Manifold topological deep learning for biomedical data 1.00
Small intestinal microbial fiber metabolism dysfunction in celiac disease 0.25
Revealing abrupt transitions from goal-directed to habitual behavior 1.00
Pathogenic variants in the cohesin loader subunit MAU2 underlie a distinct Cornelia de Lange Syndrome subtype 0.22
A bridge-like lipid transfer protein is critical for generation of invasive stages in malaria parasites 0.10
Accumulation of virtual tokens towards a jackpot reward enhances performance and value encoding in dorsal anterior cingulate cortex 0.50
Ultrasmall oral modulate gingival immunoactivation through type IV pili and TLR2-dependent endocytosis 0.96
Sustained visceral fat loss is associated with attenuated brain atrophy and improved cognitive function in late midlife 0.13
Cortex-wide characterization of decision-making neural dynamics during spatial navigation 1.00
Post-pandemic changes in population immunity have reduced the likelihood of emergence of zoonotic coronaviruses 0.17
IgA autoantibodies promote inflammation, Th17 polarization and fibrotic responses in hidradenitis suppurativa 0.92
Anterior cingulate neurons combine outcome monitoring of past decisions with ongoing movement signals 1.00
Cross-order detection of bacteriophage transduction in microbial communities using RNA barcoding 1.00
An epithelial morphogenetic program for maximal urine concentration 1.00
Multi-omic identification of key transcriptional regulatory programs during endurance exercise training in rats 1.00
Genomic inference of sites of transmission during regional spread of blaNDM Klebsiella pneumoniae in Michigan 1.00
Loss of polarity by Cdc42 depletion and oncogenic Kras activation in the mouse intestinal epithelia leads to a necrotizing enterocolitis (NEC)-like disease 1.00
Neural circuit models for evidence accumulation through choice-selective sequences 1.00
Single-cell multi-omic analysis of mitochondrial mutational mosaicism and dynamics 0.07
Dynamics of phage-host interactions in Bacteroides fragilis resolved by single-cell transcriptomics 0.90
Unpacking sources of transmission in HIV prevention trials with deep-sequence pathogen data 0.60
Periplasmic gatekeeping of phage DNA entry by an rSAM enzyme matured effector with HxS repeats 0.07
Cortical-limbic circuit dynamics of approach-avoidance conflict in humans 0.97
The role of amygdala GABA neurons in controlling stress and reproduction in female mice 0.04
Transcriptional regulation of the pneumococcal capsule can dictate serotype-specific infection 0.85
CAMPER: mechanistic artificial intelligence for designing peptides that target MRSA persisters 0.83
CXCR4-tropic HIV-1 infection in an immunocompetent monkey model 1.00
Infection-acquired protection against SARS-CoV-2 infection and clinical severity by number of prior infections 0.27
Recurrent and novel evolutionary pathways drive in vitro HIV-1 lenacapavir resistance with diverse phenotypic consequences 1.00
Assessing the micromechanical architecture of joint tissues with speckle rheological microscopy 1.00
The genetic basis of dermatophytosis skin infection susceptibility 0.29
Segmented filamentous bacteria are worldwide human gut commensals 0.08
Dolutegravir restores gut microbiota in late-stage HIV-1 unlike darunavir: an open-label, randomized clinical trial 0.00
HIV-seq reveals gene expression differences between HIV-transcribing cells from viremic and suppressed people with HIV 0.98
Contrast-free identification of glioma blood-brain barrier status via generative diffusion AI and non-contrast MRI 0.10
Epitope-spanning antigenic variation reprograms immunodominance and broadens immunity in sequential influenza vaccination 1.00
Attention-related modulation in the superior colliculus encodes perceptual sensitivity, but not perceptual choice 1.00
Genome-wide analysis of cardiac ventricular phenotypes reveals novel loci and therapeutic targets for heart failure 0.13
Post-treatment SIV control is associated with specific features of viral persistence before and after treatment interruption 0.06
Beta cell-derived cholecystokinin drives obesity-associated pancreatic adenocarcinoma development 1.00
DUSP26 protects against acute kidney injury by dephosphorylating p53 at serine 312 0.07
SEL1L-HRD1 ER-associated degradation facilitates prohormone convertase 2 maturation and glucagon production in islet α cells 1.00
Multi-modal skin atlas identifies a multicellular immune-stromal community associated with disrupted cornification and specific T cell expansion in atopic dermatitis 1.00
Regional nonsense constraint offers biological and clinical insights into genetic disease 0.07
A ketogenic diet enhances aerobic exercise adaptation and promotes muscle mitochondrial remodeling in hyperglycemic male mice 0.96
Evaluating spatially targeted HIV interventions and harm reduction services among people who inject drugs in a high-burden setting 0.67
Context-dependent translation inhibition as a cancer therapeutic modality 1.00
Using electronic health records to assess the relationship between colonization pressure and nosocomial pathogen acquisition 0.96
Conformational landscape of HIV-1 Env from closed to fully open 1.00
Subtypes of adolescent major depressive disorder characterized by divergent information dynamics in sensory-association cortices 0.15
In situ structures of the portal-neck-tail complex of bacteriophage T4 inform a viral genome positioning mechanism 0.77
Developmental plasticity enables an intestinal tapeworm to adapt to dietary stress 0.06
Mitochondrial heteroplasmy is a risk factor for the development of chronic lymphocytic leukemia 1.00
Loss-of-function variants in the CAPN1 activator cause X-linked spastic ataxia 0.01
Sustained physical activity offers benefits beyond activity volume in chronic disease prevention 0.80
Tissue-resident macrophage survival depends on mitochondrial function regulated by SerpinB2 in chronic inflammation 1.00
Multi-modal AI for opportunistic screening, staging and progression risk stratification of steatotic liver disease 0.07
Ecological partitioning enables phage–antibiotic cooperation in a human Pseudomonas infection 1.00
A 7 T fMRI dataset of synthetic images for out-of-distribution modeling of vision 0.50
Multicountry genomic analysis underscores regional cholera spread in Africa 0.09
Devaluation of response-produced safety signals reveals circuits for goal-directed versus habitual avoidance in dorsal striatum 1.00
Recombinant zoster vaccine is associated with a reduced risk of dementia 1.00
Cryo-EM structures of bacteriophage T4 portal-neck assembly intermediates reveal a viral genome retention mechanism 0.38
Urinary clusterin as a biomarker of human kidney disease progression and response to the endothelin receptor antagonist atrasentan: An exploratory analysis from the SONAR trial 0.64
Immune-mediated protection and enhancement of dengue drives patterns of infant cases in Brazil 0.42
Prefrontal chandelier cells encode stimulus salience to influence learning in male mice 0.08
Daratumumab in systemic lupus erythematosus: a single-arm phase 2 trial 0.02
Biomarker-integrated prognostic stagings for Alzheimer’s Disease 0.07
Early detection of aberrant cell fate and repair using circulating progenitor cells in patients with heterotopic ossification 1.00
Safety and biologic activity of a bispecific T cell receptor targeting HIV Gag in males living with HIV: a first-in-human trial 0.11
Molecular signatures of resilience to Alzheimer’s disease in neocortical layer 4 neurons 1.00
High-throughput methods leveraging robotics and computer vision for the development of therapeutic phage cocktails 1.00
Prenatal Zika virus exposure disrupts social-emotional development and cortical visual function in infant macaques 1.00
VSIG10L is a major determinant of esophageal homeostasis and inherited predisposition to Barrett’s esophagus 1.00
Geographic spillover of antimicrobial resistance from mass distribution of azithromycin 0.77
Electrographic cue-reactivity co-localizes with accumbens deep brain stimulation in a case of opioid use disorder 0.93
Targeting mGlyR with nanobodies for depression 0.54
A stabilized tandem antigen chimera that elicits potent malaria transmission-reducing activity 0.55
Bradyzoite subtypes rule the crossroads of development 0.92
An H5N1 clade 2.3.4.4b virus vaccine that elicits cross-protective antibodies against conserved domains of H5 and N1 glycoproteins 0.90
Using the linear references from the pangenome to discover missing autism variants 0.74
Synaptic and intrinsic membrane defects disrupt early neural network dynamics in Down syndrome 0.04
No evidence of immediate or persistent analgesic effect from a single dose of psilocybin in three mouse models of pain 1.00
Impact and cost-effectiveness of doxycycline post-exposure prophylaxis in Australian men who have sex with men 0.04
An ultra-long-acting dimeric bictegravir prodrug defined by a short pharmacokinetic tail 1.00
Endothelial cell responses in sepsis are attenuated by targeting truncated procalcitonin 0.07
Unbiased clustering of acute-on-chronic liver failure patients using machine learning in a real-world ICU cohort 0.27
Differential membrane lipid disruption by lipopeptide antibiotics, colistin and turnercyclamycins 1.00
Vibrio cholerae serotype impacts pathogenicity 1.00
Loss of Fsr quorum sensing promotes biofilm formation and worsens outcomes in enterococcal infective endocarditis 0.07
Identification of antimicrobial peptides from ancient gut microbiomes 0.13
Intranasal unadjuvanted LcrV boosts parental OMV primed lung immunity against pneumonic plague in mice 1.00
Genomics reveal persists during long-term urinary catheterization despite antimicrobial therapy and catheter exchanges 1.00
Intranasal replicon vaccine establishes mucosal immunity and protects against H5N1 and H7N9 influenza 1.00
Time-dependent deployment of medial prefrontal cortical representations in male mice 0.21
The transcription factor HHEX maintains glucocorticoid levels and protects adrenals from androgen-induced lipid depletion 0.87
Dictionary of human intestinal organoid responses to secreted niche factors at single cell resolution 1.00
Endothelial IRE1α promotes thrombospondin-1 mRNA decay and supports metabolic stress adaptation of pancreatic islets 0.04
Antisense oligonucleotides to polymorphisms expand targets and rescue patient-derived neurons in vitro 1.00
Dynamins maintain nuclear envelope homeostasis and genome stability 0.05
Integrative transcriptome-wide association analyses reveal PRKCG-linked GABAergic dysfunction in Fragile X-associated tremor/ataxia syndrome 1.00
Computational and neural mechanisms underlying the influence of action affordances on value learning 1.00
Antecedent enhancer activity predicts future susceptibility to seizures in mice 1.00
Prehospital real-time AI for trauma mortality prediction: a multi-institutional and multi-national validation study 0.20
Efficacy and safety of cAMP signalling-biased GLP-1 analogue ecnoglutide monotherapy versus placebo in patients with type 2 diabetes (EECOH-1): a multi-centre, randomised, double-blind, placebo-controlled, phase 3 trial 0.03
Adjuvanted influenza vaccination increases pre-existing H5N1 cross-reactive antibodies 0.20
Individual and population-level risk factors for new HIV infections among adults in Eastern and Southern Africa 0.02
Molecular characterisation of the Bacillus subtilis SpbK antiphage defence system 0.25
Effectiveness of the 2024–2025 KP.2 COVID-19 vaccines in the United States during long-term follow-up 1.00
Meta-analysis of 22,710 human microbiome metagenomes defines an oral-to-gut microbial enrichment score and associations with host health and disease 0.50
Dynamic neutrophil-keratinocyte communication network centered on IL-36/TNFSF15 responses characterizes inflammatory responses in generalized pustular psoriasis 0.79
Rational design of flavivirus E protein vaccine optimizes immunogenicity and mitigates antibody dependent enhancement risk 1.00
Reaching elimination of onchocerciasis transmission with long-term vector control and ivermectin treatment in Togo 0.17
MIDAS: rapid, multiplexed molecular profiling for integrated host–pathogen analysis 0.75
Minor SHIV variants abrogate protective efficacy of broadly neutralizing antibodies in rhesus macaques 1.00
Gut microbiota modulates aversive learning and memory of honeybees (Apis mellifera) 0.10
A genome-wide CRISPR screen identifies GRA38 as a key regulator of lipid homeostasis during Toxoplasma gondii adaptation to lipid-rich conditions 0.70
Spatially heterogeneous acetylcholine dynamics in the striatum promote behavioral flexibility 0.11
NutriSighT: Interpretable Transformer Model for Dynamic Prediction of Underfeeding Enteral Nutrition in Mechanically Ventilated Patients 1.00
Cascades of effectiveness of next-generation insecticide-treated nets against malaria, from entomological trials to real-life conditions 0.02
A synthetic cell phage cycle 0.75
A non-spike nucleocapsid R204P mutation in SARS-CoV-2 Omicron XEC enhances inflammation and pathogenicity 0.04
Glucagon-like peptide-1 receptor agonist in large vessel occlusion treated by reperfusion therapy—a phase 2 randomized trial 0.02
Divergent transcriptional regulation of redox-homeostasis and permeability modulate rifampicin tolerance and sensitivity in Mycobacterium tuberculosis 1.00
Methylphenidate reorganizes cortical hierarchy through dopaminergic modulation 1.00
Gut bacteria-derived sphingolipids alter innate immune responses to oral cholera vaccine antigens 0.60
Microbiome analysis of 940 lung cancers in never-smokers reveals lack of clinically relevant associations 0.56
Concurrent TB and HIV therapies control TB reactivation during co-infection but not chronic immune activation 1.00
Plasma proteomic profiles identify biomarkers predicting Crohn’s disease up to 16 years before onset 0.05
An antimicrobial daptide from human skin commensal Staphylococcus hominis protects against skin pathogens 0.96
Gut Phage Biobank: a collection of bacteriophages targeting human commensal bacteria 0.09
3D imaging of human pancreas suggests islet size and endocrine composition influence their loss in type 1 diabetes 1.00
Anti-neuraminidase and anti-HA stalk antibodies reduce the susceptibility to and infectivity of influenza A/H3N2 virus 0.41
Structural and immunological characterization of the H3 influenza hemagglutinin during antigenic drift 0.61
A corticospinal signature for interindividual pain sensitivity 0.08
In vivo base editing rescues ADPKD in a humanized mouse model 1.00
High-resolution analysis of the human T-cell leukemia virus capsid protein reveals insights into immature particle morphology 1.00
Multiplex serology reveals age-specific immunodynamics of respiratory pathogens in the wake of the COVID-19 pandemic 0.74
Photo-reversible amyloid nanoNETs for regenerative antimicrobial therapies 0.06
Limitations in PPARα-dependent mitochondrial programming restrain the differentiation of human stem cell-derived β cells 0.96
Enhanced neural plasticity in monkey TE compared to TEO during learning of a feature-ambiguous visual categorization task 0.67
Distinct structural features of Pseudomonas aeruginosa ATP synthase revealed by cryo-electron microscopy 0.33
An outer membrane vesicle vaccine prevents lung pathology in a macaque model of pneumonic melioidosis 0.87
Epigenetic regulation of cocaine intake through dopaminergic control of cholinergic interneurons in male mice 1.00
Pre-existing cross-reactive immunity to highly pathogenic avian influenza 2.3.4.4b A(H5N1) virus in the United States 1.00
Clonal cell states link gastroesophageal junction tissues with metaplasia and cancer 1.00
Nef stabilizes actin to prevent HIV-1 sensing by RIG-I-like receptors 0.27
Retro-inversion imparts antimycobacterial specificity to host defense peptides 1.00
Occupational physical activity and incidence and mortality of 14 cancers in 404,249 adults 0.07
Antibiotic-resistance plasmid amplified among MRSA cases in an urban jail and its connected communities 1.00
VIRGO2: an enhanced gene catalog of the vaginal microbiome provides insights into its functional and ecology complexity 0.89
Immunologic and biophysical features of the BNT162b2 JN.1 and KP.2 adapted COVID-19 vaccines 0.90
Intranasal cocaine self-administration in male mice 1.00
A bypass gateway from cholesterol to sex steroid biosynthesis circumnavigates CYP17A1 1.00
Microbial Product Cocktails for Personalized Cancer Immunotherapy 1.00
Sprint interval exercise disrupts mitochondrial ultrastructure driving a unique mitochondrial stress response and remodelling in men 0.02
The asymmetric opening of HIV-1 Env by a potent CD4 mimetic enables anti-coreceptor binding site antibodies to mediate ADCC 0.71
The role of attention in multi attribute decision making 0.61
Contribution of amygdala to dynamic model arbitration under uncertainty 1.00
Plastic associated endocrine disruptors reduce Nicastrin protein and potentiate inflammation in hidradenitis suppurativa skin disease 1.00
A niche-dependent redox rheostat regulates epithelial stem cell fate 0.91
Identifying the factors governing internal state switches during nonstationary sensory decision-making 1.00
Genetic evolution of keratinocytes to cutaneous squamous cell carcinoma 0.93
Oligomerisation of Ku from Mycobacterium tuberculosis promotes DNA synapsis 0.11
The Fanconi anemia pathway repairs colibactin-induced DNA interstrand cross-links 0.85
Mechanistic basis of antimicrobial resistance mediated by the phosphoethanolamine transferase MCR-1 0.83
Polymerase theta repairs persistent G1-induced DNA breaks in S-phase during class switch recombination 0.22
Defining the role of β-cell IRE1α/XBP1 pathway and its gene regulatory network components in non-obese diabetic mice 1.00
Disrupted theta synchronization and synaptic connectivity in the visual cortex of Fmr1 KO mice 0.93
Fasting hijacks proximal tubule circadian control mechanisms to regulate glucose reabsorption via the Nrf1/Sglt2 pathway in mice 1.00
Intravaginal delivery of mRNA-encoded antibodies with enhanced breadth and potency for SHIV/HIV protection 1.00
High expression of interleukin-18 receptor alpha correlates with severe respiratory viral disease and defines T cells with reduced cytotoxic signatures 0.24
A systematic review and meta-analysis of the impact of vaccination on prevention of long COVID 0.22
A four-gene signature from blood to exclude bacterial etiology of lower respiratory tract infection in adults 1.00
Prevalence study in Cameroon identifies Brucella abortus as the endemic Brucella species in livestock 0.53
A genome-wide CRISPR screen identifies the TNRC18 gene locus as a regulator of inflammatory signaling 1.00
GII.17 norovirus re-emerged in the 2020s as a result of dynamic and adaptive evolutionary processes 0.67
Ventral tegmental area GABA neurons integrate positive and negative valence 1.00
Solving the where problem and quantifying geometric variation in neuroanatomy using generative diffeomorphic mapping 0.90
Structural insights into scaffold-guided assembly of the Pseudomonas phage D3 capsid 1.00
A rapid and dynamic role for FMRP in the plasticity of adult neurons 0.88
Human gut prophage landscape identifies a prophage-mediated fucosylation mechanism alleviating colitis 0.07
The ANTsX ecosystem for mapping the mouse brain 1.00
Assembly of the infant gut microbiome and resistome are linked to bacterial strains in mother’s milk 1.00
HIV-1 envelope trimer vaccine induces sex-associated differences in antibody responses: a phase 1 clinical trial 0.31
Variant-specific antibody correlates of protection against SARS-CoV-2 Omicron symptomatic and overall infections 0.47
Germline pathogenic variation impacts somatic alterations and patient outcomes in pediatric central nervous system tumors 0.97
Adaptive stretching of representations across brain regions and deep learning model layers 0.38
Sex-specific role of the 5-HT2A receptor in psilocybin-induced extinction of opioid reward 1.00
Implantable bioelectronics for gut electrophysiology 0.24
Experimental phage evolution results in expanded host ranges against antibiotic resistant isolates 0.89
Mitochondria relay cholesterol signal exacerbates osteoarthritis in mice 0.05
Stable intracranial imaging of dura mater-engrafted pancreatic islet cells in awake mice 0.05
Long COVID trajectories in the prospectively followed RECOVER-Adult US cohort 1.00
Vascularization of neonatal liver lobules presages adult liver size 1.00
Heat shock protein DNAJA2 controls insulin signaling and glucose homeostasis by preventing spontaneous insulin receptor endocytosis 0.20
Cocaine seeking and consumption are oppositely regulated by mesolimbic dopamine in male rats 1.00
Plasma p-tau217 as a biomarker of Alzheimer’s disease pathology in individuals with Down syndrome 0.07
131 genetic loci highlight immunological pathways and tissues in nasal polyposis and asthma 0.04
Poly(imidazolium ester) antibiotic forms intracellular polymer-nucleic acid biomolecular condensates and fight drug-resistant bacteria 0.10
Physical activity levels may impact on the risk of premature mortality in people with epilepsy 0.19
Salmonella multimutants enable efficient identification of SPI-2 effector protein function in gut inflammation and systemic colonization 0.08
transmission in China during the COVID-19 pandemic period (2020–2021) compared with the pre-pandemic period (2017–2019) 0.38
An intranasal adjuvanted, recombinant influenza A/H5 vaccine primes against diverse H5N1 clades: a phase I trial 1.00
In situ gut microbiota editing: enhancing therapeutic efficacy for bacterial colitis by compatible oral hydrogel microspheres with phages 0.01
Scattering approach to diffusion quantifies axonal damage in brain injury 0.75
Computational signatures of uncertainty are reflected in motor cortex excitatory neurochemistry 0.10
Harnessing microbial-derived metabolites in the urinary tract to prevent infection induced catheter encrustation 1.00
Structural insights into context-specific inhibition of bacterial translation by macrolides 1.00
Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function 0.12
Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database 0.64
Proteome atlas for mechanistic discovery and risk prediction of diabetic retinopathy 0.06
epDevAtlas: mapping GABAergic cells and microglia in the early postnatal mouse brain 1.00
Prelimbic cortex to ventral tegmental area projection regulates early social isolation stress-potentiated heroin seeking in mice 1.00
Single-cell mRNA-regulation analysis reveals cell type-specific mechanisms of type 2 diabetes 0.04
A US case-control study to estimate infant group B streptococcal disease serological thresholds of risk-reduction 1.00
Neurocomputational basis of learning when choices simultaneously affect both oneself and others 0.71
Alpha-ketoglutarate mitigates insulin resistance and metabolic inflexibility in a mouse model of Ataxia-Telangiectasia 0.25
Mosquito salivary sialokinin reduces monocyte activation and chikungunya virus-induced inflammation via neurokinin receptors 0.02
Thalamic regulation of reinforcement learning strategies across prefrontal-striatal networks 0.56
Virus-inspired lipopeptide-derived nucleic acid delivery to cartilage for osteoarthritis therapy 0.07
Bacterial sexually transmitted infections and related antibiotic use among individuals eligible for doxycycline post-exposure prophylaxis in the United States 1.00
The neural basis for uncertainty processing in hierarchical decision making 1.00
Ultrapotent human antibodies lock E protein dimers central region of diverse DENV3 morphological variants 0.10
Genome-wide CRISPR Screen Identifies Sec31A as a Key Regulator of Alpha Cell Survival 0.83
Deep mutational scanning of the human insulin receptor ectodomain to inform precision therapy for insulin resistance 0.13
Transcriptional impacts of substance use disorder and HIV on human ventral midbrain neurons and microglia 1.00
Dopamine dynamics during stimulus-reward learning in mice can be explained by performance rather than learning 0.71
Integrated single-cell multiomic profiling of caudate nucleus suggests key mechanisms in alcohol use disorder 0.86
Experimental glycopeptide antibiotic EVG7 prevents recurrent Clostridioides difficile infection by sparing members of the Lachnospiraceae family 0.20
Combined crystallographic fragment screening and deep mutational scanning enable discovery of Zika virus NS2B-NS3 protease inhibitors 0.25
Neural coding of choice and outcome are modulated by uncertainty in orbitofrontal but not secondary motor cortex 1.00
Human pancreatic α-cell heterogeneity and trajectory inference analyses reveal SMOC1 as a β-cell dedifferentiation gene 1.00
Within-host genetic diversity of pneumococcal serotype 3 during one-year prolonged carriage in a healthy adult 0.03
Transient rapamycin treatment avoids unwanted host immune responses toward AAV-delivered anti-HIV antibodies 1.00
Prenatal exposure to Zika virus shapes offspring neutrophil function in a sex-specific manner 1.00
Cross-ancestral GWAS identifies 29 variants across head and neck cancer subsites 0.02
Reduced brain structural similarity is associated with maturation, neurobiological features, and clinical status in schizophrenia 0.18
Molecular cartography of the human down syndrome and trisomic mouse brain 0.05
Psilocybin during the postpartum period induces long-lasting adverse effects in both mothers and offspring 1.00
Motion impact score for detecting spurious brain-behavior associations 1.00
HIV vaccine candidate ΔV1gp120 formulated in ALFQA adjuvant augments mucosal immunity in female macaques 1.00
Rising dengue risk with increasing El Niño–Southern Oscillation amplitude and teleconnections 0.14
A single residue in the yellow fever virus envelope protein modulates virion architecture and antigenicity 0.06
Transmission dynamics of sequence type 131 in households—a one health prospective cohort study 0.05
A conserved long-range RNA interaction in SARS-CoV-2 recruits ADAR1 to enhance virus proliferation 0.06
Parallel neuronal structural plasticity with memory trace formation in the orbitofrontal cortex 1.00
Quantifying the impact of a broadly protective sarbecovirus vaccine in a future SARS-X pandemic 0.03
VTA monosynaptic connections by local glutamate and GABA neurons and their distinct roles in behavior 1.00
High expression of Rex-orf-I and HBZ mRNAs and bronchiectasis in lung of HTLV-1A/C infected macaques 0.95
Corticonigral projections recruit substantia nigra pars lateralis dopaminergic neurons for auditory threat memories 1.00
Artery formation in the intestinal wall and mesentery by intestine-derived Esm1+ endothelial cells 0.11
An integrated multi-omic natural history study of human development, sexual dimorphism, and the effects of trisomy 21 1.00
GPS Pipeline: portable, scalable genomic pipeline for Streptococcus pneumoniae surveillance from Global Pneumococcal Sequencing Project 0.40
Comparative single-cell and spatial profiling of anti-SSA-positive and anti-centromere-positive Sjögren’s disease reveals common and distinct immune activation and fibroblast-mediated inflammation 0.03
Naiavirus: an enveloped giant virus with a pleomorphic, flexible tail 0.10
Social exposome and brain health outcomes of dementia across Latin America 0.30
Caudate serotonin signaling during social exchange distinguishes essential tremor and Parkinson’s disease patients 0.95
Structural basis for HIV-1 capsid adaption to a deficiency in IP6 packaging 0.33
Hyaluronidase-enhanced subcutaneous delivery of bNAbs: a phase 1 randomized controlled clinical trial in HIV-uninfected women 0.67
NEXN protects against vascular calcification by promoting SERCA2 SUMOylation and stabilization 0.07
Response splicing quantitative trait loci in primary human chondrocytes identify putative osteoarthritis risk genes 1.00
Axial nephron fate switching demonstrates a plastic system tunable on demand 1.00
Prolonged exposure to food odors suppresses feeding via an olfactory bulb-to-hypothalamus circuit 1.00
Neural correlates of human fear conditioning and sources of variability in 2199 individuals 0.23
Anti-restriction functions of injected phage proteins revealed by peeling back layers of bacterial immunity 1.00
Molecular mechanisms of thiazide-like diuretics-mediated inhibition of the human Na-Cl cotransporter 1.00
Corticotropin-releasing hormone modulates NREM sleep consolidation through the thalamic reticular nucleus 0.33
Modelling transmission of Middle East respiratory syndrome coronavirus in camel populations and the potential impact of animal vaccination 0.17
Plant-derived hydrogel and photosynthetic nano-units for myocardial infarction therapy 0.75
Genkwanin glycosides are major active compounds in Phaleria nisidai extract mediating improved glucose homeostasis by stimulating glucose uptake into adipose tissues 0.06
High-throughput investigation of cyclin docking interactions reveals the complexity of motif binding determinants 0.27
A chronic Acinetobacter baumannii pneumonia model to study long-term virulence factors, antibiotic treatments, and polymicrobial infections 1.00
A decision-space model explains context-specific decision-making 1.00
Obesity-associated macrophages dictate adipose stem cell ferroptosis and visceral fat dysfunction by propagating mitochondrial fragmentation 0.05
Tonic dopamine and biases in value learning linked through a biologically inspired reinforcement learning model 1.00
A continuously oxygenated macroencapsulation system enables high-density packing and delivery of insulin-secreting cells 1.00
AI-driven fusion of multimodal data for Alzheimer’s disease biomarker assessment 1.00
Gastrointestinal neuroprosthesis for motility and metabolic neuromodulation 1.00
DeepISLES: a clinically validated ischemic stroke segmentation model from the ISLES'22 challenge 0.08
Vaccination with adhesin Abp2D provides protection against catheter-associated urinary tract infection 1.00
Real-time prediction of intensive care unit patient acuity and therapy requirements using state-space modelling 1.00
Human cytomegalovirus induces neuronal gene expression through IE1 for viral maturation 0.79
Seedless: on-the-fly pulse calculation for NMR experiments 0.06
Exome analysis links kidney malformations to developmental disorders and reveals causal genes 0.51
The HM-TARGET personalised real-time haemodynamic targets in critical care 0.86
Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations 1.00
Antimicrobial peptide class that forms discrete β-barrel stable pores anchored by transmembrane helices 0.64
IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes 0.80
Plasmodium falciparum egress disrupts endothelial junctions and activates JAK-STAT signaling in a microvascular 3D blood-brain barrier model 0.04
Three positively charged binding sites on the eastern equine encephalitis virus E2 glycoprotein coordinate heparan sulfate- and protein receptor-dependent infection 1.00
Higher-order and distributed synergistic functional interactions encode information gain in goal-directed learning 0.06
Inhibition mediated by group III metabotropic glutamate receptors regulates habenula activity and defensive behaviors 0.04
Strengthening phage resistance of Streptococcus thermophilus by leveraging complementary defense systems 0.25
Health risks and genetic architecture of objectively measured multidimensional sleep health 0.17
A single mutation may contribute to accelerated evolution of SARS-CoV-2 toward Omicron 0.02
Comparative genomics of the parasite Trichomonas vaginalis reveals genes involved in spillover from birds to humans 0.67
Open-source computational pipeline flags instances of acute respiratory distress syndrome in mechanically ventilated adult patients 1.00
Cryo-EM structures of Nipah virus polymerases and high-throughput RdRp assay development enable anti-NiV drug discovery 1.00
Plasma proteomics for biomarker discovery in childhood tuberculosis 0.62
Human spinal cord activation during filling and emptying of the bladder 0.97
Evaluating the safety of XBB.1.5-containing COVID-19 mRNA vaccines using a self-controlled case series study 0.79
Paradoxical mTORC1-Dependent microRNA-mediated Translation Repression in the Nucleus Accumbens of Male Mice Consuming Alcohol Attenuates Glycolysis 1.00
Host albumin redirects Candida albicans metabolism to engage an alternative pathogenicity pathway 0.03
Computational exploration of global venoms for antimicrobial discovery with Venomics artificial intelligence 1.00
Carbene formation as a mechanism for efficient intracellular uptake of cationic antimicrobial carbon acid polymers 0.06
Intracellular pathogen effector reprograms host gene expression by inhibiting mRNA decay 1.00
Genome sequencing is critical for forecasting outcomes following congenital cardiac surgery 1.00
Striatal dopamine can enhance both fast working memory, and slow reinforcement learning, while reducing implicit effort cost sensitivity 0.38
Identification of gut bacteria reductases that biotransform steroid hormones 0.95
Towards fair decentralized benchmarking of healthcare AI algorithms with the Federated Tumor Segmentation (FeTS) challenge 0.40
A point-of-care diagnostic for drug-induced liver injury using surface-enhanced Raman scattering lateral flow immunoassay 0.29
Genetic risk-dependent brain markers of resilience to childhood Trauma 0.03
Impact of doxycycline pre-exposure prophylaxis (doxyPrEP) for sexually transmitted infections on the microbiome of men who have sex with men on HIV PrEP 0.14
Pancreatic β-cell regeneration in situ by the ALK3 agonist THR-123 0.88
Immune correlates analysis of mRNA-1345 RSV vaccine efficacy clinical trial 0.89
Variants in cause a novel oculo vertebral renal syndrome 0.76
Cocaine-context memories are transcriptionally encoded in nucleus accumbens Arc ensembles 1.00
Pol θ-mediated end-joining uses microhomologies containing mismatches 1.00
Context flexibly modulates cue representations in visual cortex 1.00
Potential impact and cost-effectiveness of long-acting injectable lenacapavir plus cabotegravir as HIV treatment in Africa 0.38
Macrophage-induced reduction of bacteriophage density limits the efficacy of in vivo pulmonary phage therapy 0.27
Genome-wide association meta-analysis of human olfactory identification discovers sex-specific and sex-differential genetic variants 0.17
Genomic landscape of virus-associated cancers 0.69
Aerobic and resistance exercise-regulated phosphoproteome and acetylproteome modifications in human skeletal muscle 1.00
Dual role of circulating and mucosal Vδ1 T cells in the control of and contribution to persistent HIV-1 infection 0.83
Spatial and single cell mapping of castleman disease reveals key stromal cell types and cytokine pathways 0.75
Selfish mutations promote age-associated erosion of mtDNA integrity in mammals 1.00
Yanomami skin microbiome complexity challenges prevailing concepts of healthy skin 0.85
Type 1 interferon signature and allograft inflammatory factor-1 contribute to refractoriness to TNF inhibition in ankylosing spondylitis 0.07
Pancreatic islet β-cell subtypes are derived from biochemically-distinct and nutritionally-regulated islet progenitors 1.00
Context-invariant socioemotional encoding by prefrontal ensembles 1.00
An intracranial dissection of human escape circuits 0.22
Immunogenicity and safety of mRNA-based seasonal influenza vaccines encoding hemagglutinin and neuraminidase 1.00
Characterizing trachoma elimination using serology 0.43
Oropouche virus infects human trophoblasts and placenta explants 1.00
ACSS2 protects against alcohol-induced hepatocyte ferroptosis through regulation of hepcidin expression 0.17
Proteomic analysis of Down syndrome cerebrospinal fluid compared to late-onset and autosomal dominant Alzheimer´s disease 0.39
HIV-1 vif mediates ubiquitination of the proximal protomer in the APOBEC3H dimer to induce degradation 0.64
Mosquito immune cells enhance dengue and Zika virus infection in Aedes aegypti 1.00
Acute stress causes sex-specific changes to ventral subiculum synapses, circuitry, and anxiety-like behavior 1.00
Prion-induced ferroptosis is facilitated by RAC3 0.37
Confirmation bias through selective readout of information encoded in human parietal cortex 0.29
Coordinated early immune response in the lungs is required for effective control of SARS-CoV-2 replication 0.36
Role of the upper airway microbiota in respiratory virus and bacterial pathobiont dynamics in the first year of life 0.46
Distinct spatially organized striatum-wide acetylcholine dynamics for the learning and extinction of Pavlovian associations 1.00
FXYD2 marks and regulates maturity of β cells via ion channel-mediated signal transduction 1.00
Molecular basis of the urate transporter URAT1 inhibition by gout drugs 0.82
Antigen persistence and TLR stimulation contribute to induction of a durable HIV-1-specific neutralizing antibody response 0.93
Loss of CD98HC phosphorylation by ATM impairs antiporter trafficking and drives glutamate toxicity in Ataxia telangiectasia 1.00
8 2.93
Mosaic integration of spatial multi-omics with SpaMosaic 0.50
Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling 0.21
Central role of glycosylation processes in human genetic susceptibility to SARS-CoV-2 infections with Omicron variants 0.10
Proteome-wide model for human disease genetics 0.70
Genome-wide association study and polygenic risk prediction of hypothyroidism 0.25
Genome-wide association analyses identify distinct genetic architectures for early-onset and late-onset depression 0.02
Uncovering the multivariate genetic architecture of frailty with genomic structural equation modeling 0.16
Single-cell and spatial transcriptomics of stricturing Crohn’s disease highlights a fibrosis-associated network 1.00
7 5.35
Individual versus group-based interventions: a systematic review and meta-analysis of physical activity, functional, psychosocial and health outcomes 0.29
Hybrid neural–cognitive models reveal how memory shapes human reward learning 0.13
Emergency mental health co-responders reduce involuntary psychiatric detentions in the USA 1.00
A habit and working memory model as an alternative account of human reward-based learning 1.00
The human brain modulates sniffs according to fine-grained perceptual features of odours 1.00
Quantifying the impact of hair and skin characteristics on fNIRS signal quality for enhanced inclusivity 0.94
Speech sequencing in the human precentral gyrus 1.00
17 11.42
An inflammasome-driven differentiation program in intestinal stem cells protects against infection 0.02
The long noncoding RNA lnc13 restrains inflammatory responses to maintain oral tolerance to gluten 0.75
TGF-β mediates epigenetic control of innate antiviral responses and SIV reservoir size 0.89
Autologous neutralizing antibodies and polyfunctional T cells contribute to long-term HIV-1 post-intervention control 0.52
Piezo1-dependent activation of stromal cells ignites muscle inflammation in exercise and injury and is associated with inflammaging 1.00
Demographic and genetic factors shape the epitope specificity of the human antibody repertoire against viruses 0.02
Rapid elicitation of neutralizing Asn332-glycan-independent antibodies to the V3-glycan epitope of HIV-1 Env in nonhuman primates 1.00
Identification of a potent V3 glycan site broadly neutralizing antibody targeting an N332 glycan-independent epitope 0.41
Spatial patterning of fibroblast TGFβ signaling underlies treatment resistance in rheumatoid arthritis 0.78
Skin-derived myeloid precursors and joint-resident fibroblasts spread psoriatic disease from skin to joints 0.03
IgA-driven neutrophil activation underlies severe dengue disease after primary Zika virus infection in humans 0.76
Long COVID involves activation of proinflammatory and immune exhaustion pathways 1.00
Single-cell RNA profiling of blood CD4+ T cells identifies distinct helper and dysfunctional regulatory clusters in children with SLE 1.00
Influenza vaccine based on AS03-adjuvanted chimeric HA induces long-lived stalk-specific plasma cells in bone marrow and lymph nodes of nonhuman primates 0.95
Profiling of HIV-1 elite neutralizer cohort reveals a CD4bs bnAb for HIV-1 prevention and therapy 0.37
Distinct roles for B cell-derived LTα3 and LTα1β2 in TNF-mediated ileitis 1.00
Mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis 0.92
40 16.13
Population-scale genomic medicine with the Hong Kong Genome Project 0.01
Integrated epidemiological and molecular data inform the relationship between precancer and cancer states of esophageal adenocarcinoma 0.01
Antisense oligonucleotide-mediated knockdown therapy in two infants with severe epileptic encephalopathy 0.87
An international mega-analysis of psychedelic drug effects on brain circuit function 0.33
Semaglutide on liver fibrosis and heart outcomes in patients at high risk of liver fibrosis: a prespecified analysis of the SELECT randomized trial 0.37
Deleterious coding variation associated with autism is shared across ancestries 0.55
Transmission dynamics of Oropouche virus in Latin America and the Caribbean 0.18
Mass azithromycin distribution and antibiotic resistance in the gut and nasopharynx: a cluster-randomized trial 0.57
A structure-based mRNA vaccine for Nipah virus in healthy adults: a phase 1 trial 1.00
Blood phosphorylated tau elevation as a biomarker in immunoglobulin light chain and transthyretin amyloidosis 0.06
Long-term efficacy and safety of the single-dose tetravalent Butantan dengue vaccine 0.23
Deciphering the etiology of the 2024 outbreak of undiagnosed febrile illness in Panzi, Democratic Republic of the Congo 0.09
A short-acting psychedelic intervention for major depressive disorder: a phase IIa randomized placebo-controlled trial 0.11
Innate antiviral and immune functions associated with the HIV reservoir decay after anti-PD-1 therapy 0.81
Extracorporeal liver cross-circulation using transgenic xenogeneic pig livers with brain-dead human decedents 0.81
Fecal microbiota transplantation plus immunotherapy in non-small cell lung cancer and melanoma: the phase 2 FMT-LUMINate trial 0.04
Single-cell atlas of the developing Down syndrome brain cortex 0.06
External trigeminal nerve stimulation in youth with ADHD: a randomized, sham-controlled, phase 2b trial 0.01
Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990–2023: a Global Burden of Disease Study 0.13
Estimating the number of incorrect tuberculosis diagnoses in low- and middle-income countries 0.63
Malaria vaccine protection against intradermal or venous parasites: a randomized phase 2b human challenge trial 0.16
The impact of an oral purified microbiome therapeutic on the gastrointestinal microbiome 1.00
Detection of undiagnosed liver cirrhosis via AI-enabled electrocardiogram: a pragmatic, cluster-randomized clinical trial 1.00
A meta-analysis of albuminuria as a surrogate endpoint for kidney failure 0.39
A full life cycle biological clock based on routine clinical data and its impact in health and diseases 0.08
Characterizing the physiology of circulatory arrest in humans 0.06
Neoadjuvant ipilimumab and nivolumab in resectable cutaneous squamous cell carcinoma: a randomized phase 2 trial 0.02
Varicella-zoster virus reactivation and the risk of dementia 0.38
Sonelokimab, an IL-17A/IL-17F-inhibiting nanobody for active psoriatic arthritis: a randomized, placebo-controlled phase 2 trial 0.40
Clinical validation of an AI-based blood testing device for diagnosis and prognosis of acute infection and sepsis 0.97
A consensus blood transcriptomic framework for sepsis 0.25
Prevention of type 2 diabetes through prediabetes remission without weight loss 0.05
Feasibility and clinical utility of expanded genomic newborn screening in the Early Check program 1.00
Geographical shifting of cholera burden in Africa and its implications for disease control 0.51
Effects of vutrisiran on cardiac structure and function in patients with transthyretin amyloidosis with cardiomyopathy: secondary outcomes of the HELIOS-B trial 0.62
Multimodal AI correlates of glucose spikes in people with normal glucose regulation, pre-diabetes and type 2 diabetes 0.89
T and B cell responses against Epstein–Barr virus in primary sclerosing cholangitis 0.10
TERN-501 monotherapy and combination therapy with TERN-101 in metabolic dysfunction-associated steatohepatitis: the randomized phase 2a DUET trial 1.00
Adjunct-to-insulin therapy using SGLT2 inhibitors in youth with type 1 diabetes: a randomized controlled trial 0.14
An international Delphi consensus for reporting of setting in psychedelic clinical trials 0.26
3 0.27
Bridging the dimensional gap from planar spatial transcriptomics to 3D cell atlases 0.06
Stimulus-modulated approach to steady state (SASS): a flexible paradigm for event-related fMRI 0.17
HippoMaps: multiscale cartography of human hippocampal organization 0.05
3 1.26
A disease-severity-responsive nanoparticle enables potent ghrelin messenger RNA therapy in osteoarthritis 0.96
Bioengineered photosynthetic nanothylakoids reshape the inflammatory microenvironment for rheumatoid arthritis therapy 0.25
Annexin A1 mRNA-loaded liposomes alleviate acute pancreatitis by suppressing STING pathway and promoting efferocytosis in macrophages 0.05
23 15.79
Closed-loop stimulation modulates attention shifting in children 0.09
A communication subspace relays context-dependent actions from human prefrontal to motor cortex 0.50
Neuropeptide Y co-opts neuronal ensembles for memory lability and stability 0.05
Acetylcholine demixes heterogeneous dopamine signals for learning and moving 1.00
Reduced mediodorsal thalamus activity underlies aberrant belief dynamics in a genetic mouse model of schizophrenia 1.00
Deconstruction of a memory engram reveals distinct ensembles recruited at learning 0.42
Duration between rewards controls the rate of behavioral and dopaminergic learning 1.00
Charting brain morphology in international healthy and neurological populations 0.01
The striatal indirect pathway mediates hesitation 1.00
Spinal cord Tau pathology induces tactile deficits and cognitive impairment in Alzheimer’s disease via dysregulation of CCK neurons 0.13
Dendritome mapping reveals the spatial organization of striatal neuron morphology 1.00
Attentional failures after sleep deprivation are locked to joint neurovascular, pupil and cerebrospinal fluid flow dynamics 1.00
Psychedelic 5-HT2A receptor agonism alters neurovascular coupling and differentially affects neuronal and hemodynamic measures of brain function 1.00
Single-dose psilocybin rapidly and sustainably relieves allodynia and anxiodepressive-like behaviors in mouse models of chronic pain 1.00
A pancreas–hippocampus feedback mechanism regulates circadian changes in depression-related behaviors 0.05
Differential kinematic coding in sensorimotor striatum across behavioral domains reflects different contributions to movement 1.00
Serotonergic modulation of the BNST–CeA pathway reveals sex differences in fear learning 1.00
The psychoplastogen tabernanthalog induces neuroplasticity without proximate immediate early gene activation 0.92
Individual differences in decision-making shape how mesolimbic dopamine regulates choice confidence and change-of-mind 1.00
Noradrenergic activation of the basolateral amygdala facilitates memory specificity for similar events experienced close in time 0.17
Addressing artifactual bias in large, automated MRI analyses of brain development 1.00
Suppression of binge alcohol drinking by an inhibitory neuronal ensemble in the mouse medial orbitofrontal cortex 1.00
A common computational and neural anomaly across mouse models of autism 0.46
1 1.00
Structural basis for retron co-option of anti-phage ATPase-nuclease 1.00
25 20.82
Adaptive reorganization of history encoding in the retrosplenial cortex supports flexible decision-making strategies 1.00
Canonical decision computations underlie behavioral and neural signatures of cooperation in primates 1.00
The midbrain reticular formation in contextual control of perceptual decisions 1.00
A global dopaminergic learning rate enables adaptive foraging across many options 1.00
Risk reshapes amygdala representation of choice 1.00
Dual-engram architecture within a single striatal cell type distinctly controls alcohol relapse and extinction 1.00
Noninvasive tactile stimulation engaging a thalamic-amygdala circuit ameliorates mood dysfunction in mouse models of depression-like behavior 0.07
Soluble α2δ-1, altered in disease CSF, modulates network homeostasis and rescues deficits in a neuropsychiatric mouse model 1.00
Distinct interneuronal dynamics selectively gate target-specific cortical projections in drug seeking 0.71
The representation and valuation of subgoals in the human brain during model-based hierarchical behavior 1.00
Exercise-induced activation of ventromedial hypothalamic steroidogenic factor-1 neurons mediates improvements in endurance 0.99
Temporal-orbitofrontal pathway regulates choices across physical reward and visual novelty 0.67
A neural circuit framework for economic choice: From building blocks of valuation to compositionality in multitasking 1.00
Converging dopamine pathways onto basolateral amygdala neurons encode exploration decisions 0.02
A multi-region recurrent circuit for evidence accumulation in rats 1.00
Tachykinin signaling defines distinct populations of glia in the enteric nervous system 0.85
The orbitofrontal cortex updates beliefs for state inference 1.00
Structure in noise: Recurrent connectivity shapes neural variability to balance perceptual and cognitive demands in the human brain 0.33
Hunger modulates exploration through suppression of dopamine signaling in the tail of the striatum 0.94
Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health 0.81
Competitive integration of time and reward explains value-sensitive foraging decisions and frontal cortex ramping dynamics 0.92
Opposing, multiplexed information in lateral and ventral orbitofrontal cortex guides sequential foraging decisions in rats 1.00
The polypharmacology of psychedelics reveals multiple targets for potential therapeutics 0.80
Spontaneous movements and their relationship to neural activity fluctuate with latent engagement states 0.89
Adaptive reinforcement learning is causally supported by anterior cingulate cortex and striatum 0.83
7 6.83
Tumor Necrosis Factor-α Inhibition and the Unmasking of CNS Demyelination across a Large United States Health Research Network 0.83
Emergency Department Use of Ocular Point-of-Care Ultrasound and Its Utility in Diagnosis at a Tertiary Academic Medical Center 1.00
Onset of Ocular Abnormalities in Children with Hearing Loss 1.00
Tirzepatide and Reduced Risk of Diabetic Retinopathy and Related Complications: A Multicenter U.S. Cohort Study 1.00
Efficacy of an Automated Point-of-Care UVC Disinfection System for Reusable Ophthalmic Devices 1.00
Assessing the Efficacy of Ophthalmic Transfers to an Academic Level 1 Trauma Hospital: Diagnostic Accuracy and Intervention Rates 1.00
Preoperative Screening Questionnaire for Common Eye Surgeries Safely Reduces the Need for Comprehensive History & Physical Examinations 1.00
18 12.37
A cortico-subthalamic circuit rapidly engages and releases inhibition of specific movements depending on the environmental context 0.88
Biofilm spatial structure and superinfection immunity modulate inter-phage competition 1.00
Dynamic expectation strength and precision shape human pain perception through shared and dissociable α-oscillatory mechanisms 0.14
DNA damage induced by HIV-1 Vpr triggers epigenetic remodeling and transcriptional programs to enhance virus transcription and latency reactivation 1.00
The CspC:CspA heterodimer transduces germinant and co-germinant signals during Clostridioides difficile spore germination 1.00
A gut-activated NHR-86–CYP pathway mediates the neuroprotective effects of Enterococcus faecium probiotics in a nematode model of amyotrophic lateral sclerosis 1.00
Aging-related peroxisomal dysregulation disrupts intestinal stem cell differentiation through alterations of very long-chain fatty acid oxidation 0.10
Chromosome duplication causes premature aging via defects in ribosome quality control 1.00
Identification of five sleep-biopsychosocial profiles with specific neural signatures linking sleep variability with health, cognition, and lifestyle factors 0.02
Expression of intron-containing HIV-1 RNA induces NLRP1 inflammasome activation in myeloid cells 1.00
Basal forebrain cholinergic input mediates adaptive attention allocation to enhance olfactory discrimination 1.00
Extinction and subsequent updating of innate fear responses to a visual looming stimulus rely on hippocampus-dependent mechanisms. 0.19
Orbitofrontal cortex computes gaze-dependent comparisons between attributes rather than integrated values. 1.00
Attractive serial dependence arises during decision-making 0.33
The locus coeruleus influences behavior by coordinating effective integration of fear memories and sensory input 0.08
Group B Streptococci lyse endothelial cells to infect the brain in a zebrafish meningitis model 1.00
An auditory cortical-striatal circuit supports sound-triggered timing to predict future events 1.00
Neural evidence that humans reuse strategies to solve new tasks 0.63
12 9.66
Comparative whole-genome analyses of articular chondrocytes and skin fibroblasts reveal distinct genome instability landscapes in mesenchymal cell types 1.00
A machine learning classifier to identify and prioritise genes associated with murine cardiac development 0.25
Transcription factor ZEB2 is essential for ureteral smooth muscle cell differentiation 0.77
PERADIGM: Phenotype embedding similarity-based rare disease gene mapping 1.00
Exploiting peptide chirality and transport to dissect the complex mechanism of action of host peptides on bacteria 1.00
Trans-generational maintenance of mitochondrial DNA integrity in oocytes during early folliculogenesis 0.07
DLK orchestrates a modular transcriptional response to axon injury with separate roles for Fos and Jun 1.00
Mitochondrial-specific perturbation of Drosophila RNase Z in neurons leads to motor impairments, disrupted learning and neurodegeneration 1.00
Parallel regulatory circuits orchestrate biofilm formation in response to c-di-GMP levels and growth phase 0.61
A systems genetics approach identifies roles for proteasome factors in heart development and congenital heart defects 1.00
Reversion of a RND transporter pseudogene reveals latent stress resistance potential in Brucella ovis 1.00
Genetic disease risks of under-represented founder populations in New York City. 0.96
25 11.59
Contribution of nosocomial transmission to Klebsiella pneumoniae neonatal sepsis in Africa and South Asia: An observational study of infection clusters inferred from pathogen genomics and temporal data 0.17
Point-of-care early infant HIV diagnosis at birth in a pragmatic cluster-randomized trial in Mozambique and Tanzania: A comparative cost and cost-effectiveness study 0.06
Trends in HIV self-testing uptake in Africa: A modeling study of population-based surveys and HIV testing program data 0.05
Cost-effectiveness of esketamine versus alternative treatment strategies for treatment-resistant depression in Hong Kong: A multi-armed modeling study 0.03
The benefits of investments to combat HIV, tuberculosis, and malaria for primary healthcare from 2000 to 2023: An economic modeling analysis 0.57
Urban and rural prevalence of tuberculosis in low- and middle-income countries: A systematic review and meta-analysis 0.67
Effect of enhanced peer PrEP referral with HIV self-testing delivery among young Kenyan women: A randomized controlled trial of peer networks 0.50
Pain and treatment outcomes after initiating methadone vs buprenorphine among medicare patients with opioid use disorder and comorbid chronic pain: A target trial emulation 1.00
Evaluating the biomedical and behavioral drivers of HIV incidence decline in adolescent girls and young women in Uganda: A mathematical modeling study 0.52
Quantify unmet medical need across the disease landscape – A large language model-based methodology 1.00
Oral preexposure prophylaxis use and the risk of bacterial sexually transmitted infections and HIV among African women: A prospective observational cohort study 0.38
Medication adherence and its associated factors among oral pre-exposure prophylaxis (PrEP) users in China: The Real-world E-consumer Cohort of PrEP study. 0.06
Acceptability and safety of one versus three months of rifapentine and isoniazid to prevent tuberculosis in people exposed in the household or workplace in Brazil: The Ultra-Curto randomized controlled trial 0.46
Estimating the global burden of viable Mycobacterium tuberculosis infection: A mathematical modelling study 0.17
Distribution of capsule and O types in Klebsiella pneumoniae causing neonatal sepsis in Africa and South Asia: A meta-analysis of genome-predicted serotype prevalence to inform potential vaccine coverage 0.13
Evaluation of economic strengthening in South Africa and its impact on HIV, sexually transmitted infections, and teenage births: A modelling study 0.08
Diagnostic accuracy of the WHO tuberculosis treatment decision algorithms for children with presumptive tuberculosis: An individual participant data meta-analysis 0.02
Effectiveness of a brief intervention and text-based booster in the emergency department to reduce harmful and hazardous alcohol use: A pragmatic randomized adaptive clinical trial in Moshi, Tanzania 0.60
Comparative risk of post-acute sequelae following SARS-CoV-2 or influenza virus infection: A retrospective cohort study among United States adults 1.00
Psilocybin-assisted group psychotherapy and mindfulness-based stress reduction for frontline healthcare provider COVID-19-related depression and burnout: A randomized controlled trial 1.00
Effect of Paxlovid treatment during acute COVID-19 on Long COVID onset: An EHR-based target trial emulation from the N3C and RECOVER consortia 1.00
Adherence thresholds for emtricitabine-tenofovir disoproxil fumarate preexposure prophylaxis against HIV acquisition in cisgender women: A randomized directly observed dosing study 0.67
Identifying care gaps along the HIV treatment failure cascade: A multistate analysis of viral load monitoring, re-suppression, and regimen switches in Zambia 0.33
The transmission blocking activity of artemisinin-combination, non-artemisinin, and 8-aminoquinoline antimalarial therapies: A pooled analysis of individual participant data 0.11
Association of initiating CYP2D6-metabolized opioids with risks of adverse outcomes in older adults receiving antidepressants: A retrospective cohort study 1.00
2 1.03
Transgenic Tobacco Plants Expressing Synthetic Peptides: A Functional and Structural Analysis for Pathogen Resistance 0.03
Expression of mannanase and glucanases in lettuce chloroplasts and functional evaluation of enzyme cocktail against Candida albicans in oral cancer patient samples 1.00
141 113.98
Ultraslow conformational dynamics and catch bond formation of a bacterial adhesin revealed by a single-domain variant of FimH 1.00
Long-term antibody dynamics challenge the paradigm of lifelong homotypic immunity to dengue virus 0.50
Impact of sex chromosomes and gonad type in stress susceptibility in corticostriatal brain regions 1.00
Transition of the presynaptic vesicle cluster from a compact to dispersed organization during long-term potentiation 1.00
Illuminating proinflammatory myeloid cells with PET tracers targeting GPR84 0.78
Early adjunct anti-PD-L1 immunotherapy improves outcomes and restores infection-induced immune paralysis in mice with invasive pulmonary mucormycosis 0.89
Migration-linked TB epidemics: How TB elimination in high-income countries depends on the success of TB control in high-burden settings 1.00
Decisional reference point pathology: A cognitive mechanism for and a correlate of major depressive disorder in humans 0.95
Empirical validation of race-neutral normative brain morphometry models across ethnoracially diverse populations 0.11
Spectral mapping reveals a resemblance of the anesthetic brain state to both sleep and coma 0.67
Choice of cardioplegia influences metabolomics of human cardiac tissue 1.00
Distinct activity in prefrontal projections promotes temporal control of action 1.00
Contributions of the basolateral amygdala and nucleus accumbens to sustaining not just initiating cognitive effort 0.80
Incentive valence differentially engages open- and closed-loop basal ganglia circuits during movement initiation 0.98
VEGF-D-induced intraosseous lymphangiogenesis drives site-specific heterotopic bone resorption 1.00
Attention control ability is associated with frontoparietal control network interactions 1.00
Gingipain proteases from the bacterium Porphyromonas gingivalis confer protection against airway viral infection 1.00
Deep mining of the human antibody repertoire identifies frequent and genetically diverse CDRH3 topologies targetable by vaccination 1.00
Erythroferrone derived from osteoblasts regulates stress erythropoiesis 0.93
A century of suicide: Insights from long-term data in the United States 1.00
Antiretroviral therapy blocks natural selection on protective and disease-susceptible HLA-B alleles in HIV-1 infection 0.13
Mapping fast tissue dynamics with long camera exposures via intensity modulation 1.00
Bacteriophages target membrane-anchored glycopolymers to promote host cell lysis and progeny release 1.00
A discrete serotonergic circuit involved in the generation of tinnitus behavior 0.07
Medial temporal lobe encodes cognitive maps of real-world social networks 1.00
Recurrent mutations drive rapid HIV escape from two broadly neutralizing antibodies in vivo 1.00
Industrialization increases the estrogen-recycling capacity of the gut microbiome 0.50
Metabolite mimicry identifies butyrate analogs with select protective functions in the intestinal mucosa 1.00
A scalable embryonic stem cell–based platform for efficient generation of mitochondrial DNA mutant mice 1.00
The biased adenosine-rich content of the HIV-1 genome serves as a molecular signature that facilitates efficient packaging 1.00
Clade C MERS-CoV camel strains vary in protease utilization during viral entry 1.00
Mitochondrial remodeling in skeletal muscle underlies exercise-induced reversal of age-associated functional decline in mice and humans 0.14
Structural insights into SetA-mediated Rab1 glucosylation and PI3P-guided localization during early Legionella infection 0.04
Unique structural and ligand-binding properties of the Staphylococcus aureus serine hydrolase FphE 0.71
Mechanism of 30S subunit recognition and modification by the conserved bacterial ribosomal RNA methyltransferase RsmI 1.00
Identification of somatostatin+ inhibitory engrams for extinction in the basolateral amygdala 0.16
Structural insight into the CUB2 domain’s role in enteropeptidase-mediated trypsinogen activation 0.08
Reducing PTSD symptoms through unconscious intervention 0.13
Locus coeruleus–amygdala circuit disrupts prefrontal control to impair fear extinction 0.89
Predicting individual incubation of opioid craving by whole-brain functional connectivity 0.81
Fear extinction induces maladaptive generalization via noradrenergic and GABAergic systems 0.04
Lamin B receptor upregulation in metastatic melanoma causes nuclear envelope fragility in confined migration during cancer invasion 1.00
The ISR downstream effector ATF4 promotes mGluR-dependent long-term depression and associated behavior 0.09
Up-regulation of Minibrain/DYRK1A contributes to macrocephaly and brain overgrowth in a Drosophila model of fragile X syndrome 1.00
Synaptogyrin-3 plays a critical role in addiction-related dopamine dysfunction and behavioral maladaptations 1.00
Functional and antigenic constraints on the Nipah virus fusion protein 1.00
Probabilistic mapping and automated segmentation of human brainstem white matter bundles 0.83
T cell receptors for antigen on intraepithelial cytolytic T lymphocytes in celiac disease engage enterocyte HLA-E and HLA-B 0.89
Acquired motility of Babesia microti–infected red blood cells 0.88
Mammals that can develop type 2 diabetes have a similarly structured β-sheet amyloid oligomer 1.00
Intercalated bacterial biofilms are intrinsic internal components of calcium-based kidney stones 1.00
A fully synthetic Golden Gate assembly system for engineering a Pseudomonas aeruginosa phiKMV-like phage 1.00
A quorum-sensing molecule from Pseudomonas aeruginosa induces defensive multicellularity in a coinfecting pathogen 1.00
A neural circuit basis for reward-induced suppression of fear generalization and enhancement of fear extinction 0.70
Predicting epistasis across proteins by structural logic 1.00
Protein synthesis blockade prevents fear memory reactivation via inhibition of engram synapse strengthening 0.17
Distinct PlzC mechanisms integrate chemotaxis and c-di-GMP signaling to regulate Vibrio cholerae motility and biofilm formation 1.00
ACSS2 upregulation enhances neuronal resilience to aging and tau-associated neurodegeneration 1.00
Primate gut microbiota induce evolutionarily salient changes in mouse neurodevelopment 1.00
Prior novelty invigorates future mesolimbic target detection 1.00
Memory B cell development in response to mRNA SARS-CoV-2 and nanoparticle immunization in mice 0.96
NPC1 trafficking via VPS41-dependent LAMP carriers regulates endosomal cholesterol homeostasis 0.09
An ultrapotent human antibody neutralizes all maturation states of Zika virus 0.27
Conjunctive population coding integrates sensory evidence to guide adaptive behavior 0.57
Antibiotic-induced microbiota depletion impairs the proregenerative response to a biological scaffold 1.00
Maladaptive immunity to the microbiota promotes neuronal hyperinnervation and itch via IL-17A 0.87
Intrinsic neuronal network organization of a mammalian peripheral nervous system 1.00
Physical exercise increases binding of POMC to blood extracellular vesicles 0.64
Dynamic functional connectivity following cochlear implantation: Predicting speech outcomes and exploring brain network dynamics 0.17
Glomerular endothelial cells eliminate nicotinamide adenine dinucleotide to instruct CD103+ T cells in human lupus nephritis 0.08
Intracellular Acinetobacter baumannii acts as a transient reservoir in lung infection via a “persist and resist” strategy 0.80
Genetics of prelingual isolated deafness and Usher syndrome in the Maghreb and Jordan: Harnessing the potential of homozygosity 0.02
Precancer exercise capacity and metabolism during tumor development coordinate the skeletal muscle–tumor metabolic competition 1.00
Regulated coexpression of PrP from different species in mice impacts the replication and host range properties of prion strains 1.00
Cytomegalovirus disrupts Lamin A/C to control microtubule-mediated nuclear movement and cell migration 1.00
Migration and the persistence of violence 0.67
Neural representation of the decisional reference point in monkeys 1.00
Coordinated transfer of DNA between Pol θ and Pol δ resets microhomology choice during double-strand break repair 1.00
MAPK signaling and angiopoietin-2 contribute to endothelial permeability in capillary malformations 1.00
Structural basis for Lamassu-based antiviral immunity and its evolution from DNA repair machinery 0.62
Rac1 promotes proximal tubule kidney repair by coupling the actin cytoskeleton to mitochondrial function 0.96
Cognitive correlates of human endurance 1.00
Estimated impact of 2022–2023 influenza vaccines on annual hospital burden in the United States 1.00
Synergistic interactions between Candida albicans and Enterococcus faecalis promote toxin-dependent host cell damage 0.11
Genome synthesis, assembly, and rebooting of therapeutically useful high G+C% mycobacteriophages 1.00
HIV-1 Vif and Vpr cooperatively modulate the cell cycle to maximize per-cell virion production 1.00
The synergy of methylphenidate- and reconsolidation-based extinction normalizes ventromedial prefrontal function in drug addiction 1.00
Scaffold vaccination for prevention of orthopedic device infection 1.00
The temporal dynamics of self-control 1.00
LRP8 is an entry receptor for tick-borne encephalitis viruses 1.00
Learning expectations shape cognitive control allocation 0.83
Spatial gene expression analysis reveals pathological niches in Japanese encephalitis virus neuroinvasion 0.06
Lamin A/C loss promotes R-loop-mediated genomic instability and poor survival in small-cell lung cancer 0.93
All the world’s a phage 1.00
Physical activity is directly associated with total energy expenditure without evidence of constraint or compensation 0.59
Reconfiguration of brain-wide neural activity after early life adversity 1.00
Emergence of antiphage functions from random sequence libraries reveals mechanisms of gene birth 0.88
Precise gene editing of pathogenic Lamin A mutations corrects cardiac disease 1.00
Apparent learning biases emerge from optimal inference: Insights from master equation analysis 1.00
Functional diversity in GII.4 norovirus entry: HBGA binding and capsid clustering dynamics 0.93
Mapping macaque to human cortex with natural scene responses 1.00
Exceptionally broad HIV-1 neutralization via bispecific antibody–mediated prepositioning 1.00
The role of innate immunity, antibiotics, and bacteriophages in the course of bacterial infections and their treatment 0.71
FGF21 acting on the noradrenergic nervous system protects against influenza virus infection 1.00
Intranasal hemagglutinin protein boosters induce protective mucosal immunity against influenza A viruses in mice 1.00
In situ structures of the Legionella Dot/Icm T4SS identify the DotA–IcmX complex as the gatekeeper for effector translocation 1.00
De novo design of potent inhibitors of clostridial family toxins 0.42
Heterogeneity in the coordination of delta cells with beta cells is driven by both paracrine signals and low-density Cx36 gap junctions 1.00
Distinct prelimbic cortex ensembles encode response execution and inhibition 1.00
Resurfacing promotes antibacterial activity of a lipid A–binding nanobody 1.00
Lysosomal reduced thiols are essential for mouse embryonic development 0.92
Therapeutic restoration of mitochondria–endoplasmic reticulum cross talk for osteoarthritis 0.23
Activation of WNK1 signaling through Piezo1 1.00
A unified model of transient poration induced by antimicrobial peptides 1.00
Specificities of chemosensory receptors in the human gut microbiota 0.33
SHP2 genetic variants in NSML-associated RASopathies disrupt the PZR–IRX transcription factor signaling axis 1.00
Shared metabolism between a bacterial and fungal species that reside in the human gut 1.00
Negative interplay between HIV-1 Gag and amyloid precursor protein centers around competition for VPS4A and TSG101 1.00
Identification of broadly inhibitory anti-PfEMP1 antibodies by mass spectrometry sequencing of plasma IgG from a malaria-exposed child 0.18
Synergistic action of specialized metabolites from divergent biosynthesis in the human oral microbiome 1.00
Therapeutic CD8+ T cell tissue retention and immunomodulation during ART interruption fail to prevent SIV rebound 0.87
Ensemble approaches for short-term dengue fever forecasts: A global evaluation study 0.67
Structural insights into VRC01-class bnAb precursors with diverse light chains elicited in the IAVI G001 human vaccine trial 1.00
Sox11 genes affect neuronal differentiation in the developing zebrafish enteric nervous system 1.00
Striatal and cerebellar interactions during reward-based motor performance 1.00
A recurrent de novo damaging variant in EMP2 causes progressive symmetric erythrokeratoderma 0.73
A minimal model of panimmunity maintenance by horizontal gene transfer in the ecological dynamics of bacteria and phages 1.00
PyReconstruct: A fully open-source, collaborative successor to Reconstruct 1.00
Phage-based delivery of CRISPR-associated transposases for targeted bacterial editing 1.00
Cell type–specific purifying selection of synonymous mitochondrial DNA variation 0.61
Hippocampal blood oxygenation predicts choices about everyday consumer experiences: A deep-learning approach 1.00
Genetic ancestry shapes dengue virus infection in human skin explants 0.97
Contribution of glutamatergic projections to neurons in the nonhuman primate substantia nigra pars reticulata for reactive inhibition 0.75
Trichomonas vaginalis extracellular vesicles suppress IFNε-mediated responses driven by its intracellular bacterial symbiont Mycoplasma hominis 1.00
Model-based algorithms shape automatic evaluative processing 1.00
LDL receptor–mediated endocytosis of Escherichia coli α-hemolysin mediates renal epithelial toxicity 1.00
Pathogenic variants in the polycystin pore helix cause distinct forms of channel dysfunction 1.00
<atl>Repurposing a drug to punish carbapenem-resistant iAcinetobacter baumannii/i</atl> 0.82
Systemic in utero gene editing as a treatment for cystic fibrosis 1.00
Predicting high-fitness viral protein variants with Bayesian active learning and biophysics 0.88
Macropinosomes are a site of HIV-1 entry into primary CD4+ T cells 1.00
4 2.30
Interepidemic Rift Valley fever in East Africa: the recent risk landscape and projected impacts of global change 0.64
Humans choose trunk lean angles consistent with minimal metabolic costs—an integrative experimental and musculoskeletal simulation approach 0.42
Indirect feedback hinders explicit sensorimotor adaptation 1.00
Localized Rift Valley fever virus persistence explains epidemic and interepidemic dynamics and guides control strategies. 0.24
20 9.69
Interobserver Agreement in Contrast-enhanced US for Hepatic Nodules in Patients with Fontan-associated Liver Disease. 1.00
Comparison of Conventional versus Abbreviated MR Enterography: Assessing Disease Activity and Complications in Crohn Disease. 0.44
Body Composition in the General Population: Whole-body MRI-derived Reference Curves from Over 66 000 Individuals. 0.16
Telangiectatic Pulmonary Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia. 1.00
Contrast-Enhanced US Using Perfluorobutane for Diagnosing Small HCC in High-Risk Patients: Comparison with MRI LI-RADS Version 2018. 0.07
Quality of Gadoxetate-enhanced MRI versus US during Hepatocellular Carcinoma Screening in Participants with Cirrhosis. 0.93
Middle Meningeal Artery Embolization for Subdural Hematoma: CT/MRI End Points of the EMBOLISE Trial. 0.77
Establishing CT-derived Normative Liver and Spleen Volumes for Children: Validation in Regional and International Datasets. 0.13
Nephrogenic Systemic Fibrosis in Patients with Advanced Renal Dysfunction Following Gadolinium-based Contrast Agents. 1.00
C-FLAIR: Fluid-attenuated Inversion Recovery with Controlled Artifact Suppression in Brain MRI. 0.17
Deep Learning-based Opportunistic CT Osteoporosis Screening and the Establishment of Normative Values. 0.60
Standalone Endovascular Embolization versus Stereotactic Radiosurgery in the Treatment of Arteriovenous Malformations in Eloquent Brain. 0.94
Risk Stratification of Sudden Cardiac Death in Nonischemic Dilated Cardiomyopathy: Arrhythmogenic Substrate Assessment in Cardiac MRI. 0.13
A Safe MRI- and PET-guided Method for Increasing Osmotic Blood-Brain Barrier Permeability. 1.00
Intratumoral Microbiome-related MRI Model for Predicting Breast Cancer Shrinkage Pattern Following Neoadjuvant Therapy. 0.08
Prognostic Value of Global Longitudinal Strain using Automated Measurement in Cardiac MRI. 0.06
Noninvasive Tumor Profiling: Quantitative Contrast-Enhanced MRI Markers Predict PD-L1 and CTNNB1 Status in Hepatocellular Carcinoma. 0.70
Impact of LI-RADS CT and MRI Ancillary Features on Diagnostic Performance: An Individual Participant Data Meta-Analysis. 0.25
A Data-Centric Approach to Deep Learning for Brain Metastasis Analysis at MRI. 0.04
Diagnostic Performance of CT/MRI LI-RADS Version 2018 Major Feature Combinations: Individual Participant Data Meta-Analysis. 0.25
28 18.84
Reward magnitude determines reinforcement learning efficiency 1.00
Tuft dendrites in frontal motor cortex enable flexible learning 0.13
Induction of broadly neutralizing HIV antibodies by a two-step mechanism informs vaccine design 0.95
Molecular and cellular processes disrupted in the early postnatal Down syndrome prefrontal cortex 1.00
A single-cell multiomic analysis identifies molecular and gene-regulatory mechanisms dysregulated in developing Down syndrome neocortex 1.00
HNF1B integrates signals in a feed-forward loop driving kidney disease progression 0.11
DefensePredictor: A machine learning model to discover prokaryotic immune systems 1.00
Distinctive DNA sequence features define epigenetic longevity of inflammatory memory 0.73
Population genomics of Anopheles darlingi, the principal South American malaria vector mosquito 0.42
Host-derived nitrate fuels indole production by Escherichia coli to drive chronic kidney disease progression 0.73
Structural modeling reveals phage proteins that manipulate bacterial immune signaling 0.19
Task learning increases information redundancy of neural responses in macaque visual cortex 1.00
Imbalance in gut microbial interactions as a marker of health and disease 0.71
Implanted flexible electronics reveal principles of human islet cell electrical maturation 1.00
DNA origami vaccines program antigen-focused germinal centers 0.98
A cellular basis for heightened gut sensitivity in females 0.75
The specificity and structure of DNA cross-linking by the gut bacterial genotoxin colibactin 1.00
Regional encoding of enteric nervous system responses to microbiota and type 2 inflammation 0.96
Ancient origin of an urban underground mosquito 0.57
1206 genomes reveal origin and movement of Aedes aegypti driving increased dengue risk 0.49
Reversible compromise of physiological resilience by accumulation of heteroplasmic mtDNA mutations 1.00
Machine learning–based penetrance of genetic variants 1.00
Recent evolution of the developing human intestine affects metabolic and barrier functions 0.45
Mitochondria protect against an intracellular pathogen by restricting access to folate 0.18
Cryo-EM structure of endogenous Plasmodium falciparum Pfs230 and Pfs48/45 fertilization complex 0.15
Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin 0.33
Disassembly activates Retron-Septu for antiphage defense 0.95
A metabolite-based resistance mechanism against malaria 0.05
71 48.57
A STAT1/ETC/GBP1 axis represents a potential therapeutic target for noncommunicable granulomatous skin disease 0.15
Limited transmission of cervid prions to nonhuman primates provides insights into the zoonotic potential of chronic wasting disease 0.12
GRASPing experience-dependent protein expression signatures enriched for hippocampal engram cell synapses 0.03
Preemptive cardioprotection with a small molecule in rodents that suppresses genes predictive of heart failure 0.08
The metabolomic signatures mediate associations between physical frailty and metabolic dysfunction–associated steatotic liver disease 0.39
Tunable TriPcides suppress virulence factor secretion during Staphylococcus aureus infection and kill dormant cells 0.42
A multiomics atlas of the Arabidopsis nuclear envelope 1.00
Childhood immune imprinting shapes cohort and period influenza mortality 0.83
SRC-mediated phosphorylation of UBC9 regulates inflammatory and metabolic signaling in alcohol-associated liver disease 0.93
Multimodal platform for ITN efficacy: Surface chemistry, bioavailability, and mosquito behavior 0.06
Synergy and antagonism in a genome-scale model of metabolic hijacking by bacteriophages 1.00
Hemostatic B-knob–triggered microgels (BK-TriGs) to address bleeding in neonates 1.00
A microphysiologic human cervical model recapitulates microbial, immune, and pathogenic properties of sexually transmitted infections 1.00
PRISM: A unified platform for phage isolation and characterization from single-droplet microenvironments 1.00
Bacterial enzyme-responsive hydrogels for triggered delivery of antibiotics to infected wounds 1.00
Type 2 lymphocytes restrict type 3 lymphocytes during liver fibrosis and colocalize in fibroblast niches 0.71
Immunity to hemagglutinin and neuraminidase results in additive reductions in airborne transmission of influenza H1N1 virus in ferrets 1.00
Transcriptional regulation of ventral hippocampus-nucleus accumbens circuit excitability drives cocaine seeking 1.00
Rapid dopaminergic signatures in movement: Reach vigor reflects reward prediction error and learned expectation 1.00
3D reconstruction of human liver tissue at cellular resolution 1.00
Animal-associated jumbo phages as widespread and active modulators of gut microbiome ecology and metabolism 0.21
Overcoming host restrictions to enable continuous passaging of GII.3 human norovirus in human intestinal enteroids 1.00
Antigen-specific TH17 cells offset the age-related decline in durable T cell immunity 1.00
RIN3 mutations impairing binding of the Alzheimer’s disease–associated protein BIN1 lead to RAB5 hyperactivation and endosomal pathology 1.00
Lipid self-assembly dependence on hyaluronic acid size reveals biolubrication and osteoarthritic degeneration mechanisms 0.67
Whole-brain meso-vein imaging in living humans using fast 7-T MRI 0.18
Tracing 2500 years of human betaherpesvirus 6A and 6B diversity through ancient DNA 0.02
Dynamic adaptive coassembled sericin protein orchestrating stem cell development for nucleus pulposus regeneration 0.20
Febrile temperature activates the innate immune response by promoting aberrant influenza A virus RNA synthesis 1.00
Interleukin-2 is a potent latency reversal agent in people with treated HIV-1 1.00
Caspase-8 expression in CD8+ T cells promotes pathogen restriction in the brain during Toxoplasma gondii infection 1.00
Cortical dopaminergic signaling mediates planning of directional movements 1.00
Swallowable expandable fibrous capsules for nonendoscopic sampling of esophageal cells 1.00
Structural basis of bacteriophage Ur-lambda infection initiation 1.00
Liver-directed AAV gene therapy in mice corrects glycogen storage disease type IX γ2 1.00
Evasion of CARD8 activation during HIV-1 assembly 1.00
A network of basolateral amygdala projection neurons contributes to stress-induced activation of the hypothalamic-pituitary-adrenal axis 0.10
Thalamo-hippocampal pathway determines aggression and self-harm 1.00
Engineered probiotic restores GLP-1 signaling to ameliorate fiber-deficiency exacerbated colitis 0.94
Bacteriophage-loaded microneedle patches for targeted and minimally disruptive foodborne pathogen decontamination 0.03
In vivo expression of VCAM1 precedes nephron loss following kidney tubular necrosis 0.08
The designer cytokine IC7Fc attenuates atherosclerosis development by targeting hyperlipidemia in mice 0.11
Functional recovery of islet β cells in human type 2 diabetes: Transcriptome signatures unveil therapeutic approaches 0.02
Restriction of HIV-1 infectivity by interferon and IFITM3 is counteracted by Nef 1.00
BDNF-driven synaptic plasticity requires autocrine matrix metalloproteinase–9 activity 0.19
Laser speckle particle sizer (SPARSE) informs the size distribution of tissue granularities 1.00
Ethanol ingestion via frugivory in wild chimpanzees 0.58
Oropouche virus efficiently replicates and is immunostimulatory in vivo in nonhuman primate species 1.00
Grin2b-mutant mice exhibit heightened remote fear via suppressed extinction and chronic amygdalar synaptic and neuronal dysfunction 0.06
Investigating the know-do gap in antibiotics prescribing: Experimental evidence from India 0.63
Somatic mtDNA mutations at intermediate levels of heteroplasmy are a source of functional heterogeneity among primary leukemic cells 1.00
Elucidating the mechanism by which HIV-1 nucleocapsid mutations confer resistance to integrase strand transfer inhibitors 1.00
The discovery of a Legionella phage explains a key determinant of human disease 0.22
Intravenous AAV9-ATP7A plus subcutaneous copper histidinate optimizes outcomes in a lethal Menkes disease mouse model 1.00
Inhibition of craniosynostosis and premature suture fusion in Twist1 mutant mice with RNA nanoparticle gene therapy 1.00
Heparan sulfate fine-tuned interleukin-1 (IL-1) signaling inhibits insulin secretion of grafted pancreatic islets 0.04
Fluid dynamical pathways of airborne transmission while waiting in a line 0.60
TH17 cells regulate chemokine expression in epithelial cells through C/EBPβ and dictate host sensitivity to colitis and cancer immunity 0.92
A scalable ultra-long-acting tenofovir phosphonate prodrug sustains HBV suppression 1.00
Improving real-time ultrasound spine imaging with a large-aperture array 1.00
Selective engagement of prefrontal VIP neurons in reversal learning 0.20
NRBP1 and TSC22D proteins affect distal convoluted tubule physiology through modulation of the WNK pathway 0.13
Biorhythms derived from consumer wearables predict postoperative complications in children 1.00
Striatal dopamine signals errors in prediction across different informational domains 1.00
Change-of-mind neuroeconomic decision-making is modulated by LINC00473 in medial prefrontal cortex in a sex-dependent manner 1.00
Atomic-resolution structure of a chimeric Powassan tick-borne flavivirus 1.00
The human genetic variant rs6190 unveils Foxc1 and Arid5a as novel prometabolic targets of the glucocorticoid receptor in muscle 0.95
Staphylococcus aureus LukMF′ targets neutrophils to promote skin and soft tissue infection 0.94
Monoclonal antibodies targeting the FimH adhesin protect against uropathogenic E. coli UTI 1.00
Insight into human photoreceptor function: Modeling optoretinographic responses to diverse stimuli 0.75
Endothelial CLEC5A drives barrier dysfunction and vascular leakage responsible for lung injury in bacterial pneumonia and sepsis 0.08
49 36.69
Real-time in vivo analysis of murine β cells reveals autophagic flux defects before onset of autoimmune diabetes 0.93
Urinary fluorogenic reporters for noninvasive detection and staging of kidney fibrosis 0.14
VRC01 with antiretroviral initiation in infants is well tolerated, and higher concentrations associate with greater HIV-1 DNA declines 0.72
Local B cell immunity and durable memory after live-attenuated influenza intranasal vaccination of humans 0.96
Adeno-associated virus gene therapy–mediated CCR5 blockade suppresses virus replication long term in SHIV-infected macaques 1.00
Expansion of stemlike HIV-specific CD8+ T cells and limited viral epitope diversity characterize durable posttreatment control of HIV 1.00
Quantifying myocardial oxygen consumption and efficiency with motion-resolved cardiac MRI 0.84
An oral allopregnanolone prodrug bypasses liver metabolism via lymphatic transport enabling bioavailability in animals and humans 0.42
Epigenetically regulated pancreatic GABA-somatostatin signaling underlies gestational diabetes–induced glucose intolerance in offspring 0.04
AAV8 gene therapy and dietary insults together precipitate cholestatic liver disease in a mouse model of X-linked myotubular myopathy 0.29
Multiomic analyses of longitudinal plasma samples identify thromboinflammation endotypes and trajectories in patients with trauma 1.00
Crystallized colony-stimulating factor-1 receptor inhibitor protects immunoisolated allo but not xeno transplants in primates 0.85
Meteorin-like is associated with poor outcome in invasive candidiasis in mouse models and in humans 0.08
Anti-FAP CAR T cells produced in vivo reduce fibrosis and restore liver homeostasis in metabolic dysfunction–associated steatohepatitis 0.91
Dermatomyositis is characterized by JAK1-mediated monocyte-driven vasculopathy and inflammation 1.00
Anakinra restores immunological misfiring that drives influenza-associated pulmonary aspergillosis 0.02
Epidemiological and antigenic inferences from serological cross-reactivity among arboviruses 0.14
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus 1.00
snoRNA Snord3 promotes rheumatoid arthritis by epigenetic regulation of ESM1 in fibroblast-like synoviocytes in mice 0.07
Depletion of plasmacytoid dendritic cells rescues HIV-reactive stem-like CD8+ T cells during chronic HIV-1 infection 0.97
Burst-patterned stimulation restores colonic motility in preclinical models 1.00
Immunopeptidomics can inform the design of mRNA vaccines for the delivery of Mycobacterium tuberculosis MHC class II antigens 0.83
Identifying correlates of viral rebound timing and viral control in SHIV-infected infant macaques after ART interruption 1.00
Computationally designed mRNA-launched protein nanoparticle immunogens elicit protective antibody and T cell responses in mice 0.91
Sprayable extracellular matrix hydrogel reduces postoperative adhesion formation and protects healing tissues in preclinical models 0.25
CRISPR activation of the ribosome-associated quality control factor ASCC3 ameliorates fragile X syndrome phenotypes in mice 0.92
Afucosylation of anti-dengue IgG is associated with enhanced susceptibility to dengue virus infection postvaccination 0.70
Progression to rheumatoid arthritis in at-risk individuals is defined by systemic inflammation and by T and B cell dysregulation 1.00
Sex differences in HIV-1 reservoir cell selection are linked to altered innate immune profiles 1.00
A soft robotic device for rapid and self-guided intubation 1.00
Impaired TIM4-mediated efferocytosis by liver macrophages contributes to fibrosis in metabolic dysfunction–associated steatohepatitis 0.88
Functional, immunogenetic, and structural convergence in influenza immunity between humans and macaques 0.93
Dengue disease severity in humans is augmented by waning Japanese encephalitis virus immunity 0.13
The XBB.1.5 COVID-19 vaccine elicits a durable antibody response to ancestral and XBB.1.5 SARS-CoV-2 spike proteins 1.00
Resolving fibrosis by stimulating HSC-dependent extracellular matrix degradation 1.00
Antigen-Fc fusion therapy reduces severity of a model of pemphigus vulgaris without systemic immunosuppression 1.00
Synchronized dynamics of dengue across the Americas 0.46
Proviruses in CD4+ T cells reactive to autologous antigens contribute to nonsuppressible HIV-1 viremia 0.83
Nasal and systemic immune responses correlate with viral shedding after influenza challenge in people with complex preexisting immunity 1.00
Vaccination with mRNA-encoded membrane-anchored HIV envelope trimers elicited tier 2 neutralizing antibodies in a phase 1 clinical trial 1.00
Vaccination with an mRNA-encoded membrane-bound HIV envelope trimer induces neutralizing antibodies in animal models 1.00
Viral spike antigen clearance and augmented recovery in children with post-COVID multisystem inflammatory syndrome treated with larazotide 0.98
NFIA regulates articular chondrocyte fatty acid metabolism and joint homeostasis 0.90
Protective envelope dimer epitope–like antibodies are elicited against dengue virus in children after infection and vaccination 0.67
Human inner ear fluid imbalance detected by optical coherence tomography correlates with hearing loss 0.94
Adenovirus and mRNA vaccines as well as mucosal boosting improve protective efficacy against influenza virus challenge in macaques 1.00
A cationic polymer drives glycosaminoglycan assembly and secretion for preclinical osteoarthritis therapy 0.07
Nonstabilized SARS-CoV-2 spike mRNA vaccination induces broadly neutralizing antibodies in nonhuman primates 0.96
A phase 1 clinical trial shows safe, sustained, AAV-mediated expression of IL-1Ra in the human osteoarthritic knee joint 0.95
10 1.58
Glucagon-like peptide-1 receptor agonists and risk of substance use disorders among US veterans with type 2 diabetes: cohort study 1.00
Effectiveness of drug interventions to prevent delirium after surgery for older adults: systematic review and network meta-analysis of randomised controlled trials 0.10
Effects of lifestyle interventions in pregnancy on gestational diabetes: individual participant data and network meta-analysis 0.04
Benefits and harms of ADHD interventions: umbrella review and platform for shared decision making 0.05
Tai chi or cognitive behavioural therapy for treating insomnia in middle aged and older adults: randomised non-inferiority trial 0.15
Comparative efficacy and safety of exercise modalities in knee osteoarthritis: systematic review and network meta-analysis 0.02
Patterns of war related trauma in Gaza during armed conflict: survey study of international healthcare workers 0.11
Effect of lateral versus supine positioning on hypoxaemia in sedated adults: multicentre randomised controlled trial 0.02
Medications for adults with type 2 diabetes: a living systematic review and network meta-analysis 0.03
ADHD drug treatment and risk of suicidal behaviours, substance misuse, accidental injuries, transport accidents, and criminality: emulation of target trials 0.05
3 1.31
Deep single-cell decoding of human pancreatic islets reveals T2D β-cell gene expression defects 1.00
Notch signaling is a driver of glandular stem cell activity and regenerative migration after damage 0.03
RTN4IP1 is required for the final stages of mitochondrial complex I assembly and CoQ biosynthesis. 0.29
4 3.73
Predator–prey dynamics of Vibrio cholerae on chitin suggest an alternative mode of biofilm formation in marine snow conditions 1.00
Density-dependent feedback and higher-order interactions enable coexistence in phage-bacteria community dynamics 1.00
Phage infection fronts trigger early sporulation and viral entrapment in bacterial populations 0.86
Vitamin auxotrophies shape microbial community assembly on model marine particles 0.88
25 16.08
Early intervention with secukinumab prevents epigenetic scar development in new-onset psoriasis – STEPIn Mechanistic Sub-study results 0.28
A Novel Olfactory Cleft CT Staging System Reveals a Tri-Zone Anatomical Model and Biphasic Progression in Central Compartment Atopic Disease 0.14
CD25 expression marks an activated mast cell population in human nasal polyposis 1.00
Comprehensive molecular profiling of Hispanic, Black, Asian, and White atopic dermatitis via tape strip RNAseq and serum proteomics 0.94
Dupilumab normalizes the eosinophilic esophagitis disease transcriptome 1.00
Heterogeneity and clinical relevance of group 2 innate lymphoid cells subsets in nasal polyps 0.83
Deep learning and statistical methods identify novel asthma risk variants in Europeans 0.17
Incidence of autoimmune diseases in children with atopy treated with dupilumab 1.00
Multitrait analysis of genome-wide association studies expands eosinophilic esophagitis genetic susceptibility and polygenic risk scores 1.00
Establishing the PM2.5-associated inflammatory endotype of chronic rhinosinusitis 1.00
Effects of proton pump inhibitors on remodeling and fibrosis in eosinophilic esophagitis 1.00
Nasal microbiome and phageome profiles are associated with prospective respiratory viral infection risk in school-aged children 0.97
Bimekizumab long-term response in psoriasis: Mechanistic insights into efficacy level and durability 0.24
Skin tape strips identify age-specific immune, metabolic and barrier dysregulation signatures in children, adolescents, and adults with allergic asthma 1.00
Epinephrine and Emergency Medical Services Activation Recommendations During Acute Allergic Reactions in Community Settings: International Consensus Report 0.77
Targeting IL-22RA1 with Temtokibart: A Novel Approach in Atopic Dermatitis: Phase 2a Monotherapy Study Results 0.15
Remibrutinib in chronic spontaneous urticaria: 52-Week results from two phase 3 studies 0.27
Periostin promotes inflammation and neovascularization in atopic keratoconjunctivitis 0.09
Effects of type 3 and neutrophilic inflammation on type 2 chronic rhinosinusitis with nasal polyps 0.90
Resolution of Epithelial Dysfunction in Eosinophilic Esophagitis is Mediated by a HIF-1α-CD73-Adenosine Signalling Axis 0.19
Prediction and Characterization of Genetically-Regulated Expression of Asthma Tissues from African-Ancestry Populations 0.89
Massively parallel analysis of genotype-dependent enhancer activity among atopic dermatitis genetic risk variants 1.00
Comparative efficacy and safety of biologics and systemic immunomodulatory treatments for chronic urticaria: Systematic review and network meta-analysis 0.52
Inhibition of lysosomal degradation increases expression of mutant ADA2 in DADA2 monocytes 0.05
Transcriptomic profiling of vitiligo patients shows polar immune dysregulation in involved and uninvolved skin 0.67
29 15.16
Efficacy and safety of cefepime–nacubactam and aztreonam–nacubactam compared with imipenem–cilastatin for complicated urinary tract infection or acute uncomplicated pyelonephritis (Integral-1): a double-blind, randomised phase 3 trial 0.03
Enpatoran, a Toll-like receptor 7/8 inhibitor, in moderate-to-severe systemic lupus erythematosus: findings from Cohort B of a multicentre, international, double-blind, placebo-controlled dose-finding phase 2 trial 0.43
Prevalence of liver fibrosis in the general population (the LiverScreen project): a multinational European cohort study 0.01
Efficacy and safety of LEVI-04 in patients with osteoarthritis of the knee: a randomised, double-blind, placebo-controlled, phase 2 trial 0.30
Prevention of urinary stones with hydration: a randomised clinical trial of an adherence intervention 1.00
Effect of baxdrostat on ambulatory blood pressure in patients with resistant hypertension (Bax24): a phase 3, randomised, double-blind, placebo-controlled trial 0.36
Survivorship of modern total hip replacement to 30 years: systematic review, meta-analysis, and extrapolation of global joint registry data 0.08
Comparative efficacy and tolerability of antidopaminergic and muscarinic antipsychotics for acute schizophrenia: a network meta-analysis of randomised controlled trials indexed in international English and Chinese databases 0.05
Efimosfermin alfa (BOS-580) once per month in people with metabolic dysfunction-associated steatohepatitis with F2 or F3 fibrosis: results from a 24-week, randomised, double-blind, placebo-controlled, phase 2 trial 1.00
Switch to fixed-dose doravirine (100 mg) and islatravir (0·25 mg) once daily in virologically suppressed adults with HIV-1 on oral antiretroviral therapy: 48-week results of a phase 3, multicentre, randomised, open-label, non-inferiority trial 0.58
Switch to fixed-dose doravirine (100 mg) and islatravir (0·25 mg) once daily in virologically suppressed adults with HIV-1 on bictegravir, emtricitabine, and tenofovir alafenamide: 48-week results of a phase 3, multicentre, randomised, controlled, double-blind, non-inferiority trial 0.89
TRPC6 inhibition for the treatment of focal segmental glomerulosclerosis: a randomised, placebo-controlled, phase 2 trial of BI 764198 0.41
Deaths potentially averted by small changes in physical activity and sedentary time: an individual participant data meta-analysis of prospective cohort studies 0.20
Maternal and neonatal outcomes after infection with monkeypox virus clade I during pregnancy in DR Congo: a pooled, prospective cohort study 0.14
Safety and immunogenicity of a Nipah virus vaccine (HeV-sG-V) in adults: a single-centre, randomised, observer-blind, placebo-controlled, phase 1 study 0.96
A preventive care strategy to reduce moderate or severe acute kidney injury after major surgery (BigpAK-2); a multinational, randomised clinical trial 0.03
Balcinrenone in combination with dapagliflozin compared with dapagliflozin alone in patients with chronic kidney disease and albuminuria: a randomised, active-controlled double-blind, phase 2b clinical trial 0.39
Efficacy and safety of nipocalimab in patients with moderate-to-severe Sjögren's disease (DAHLIAS): a randomised, phase 2, placebo-controlled, double-blind trial 0.92
Effectiveness of high-dose influenza vaccine against hospitalisations in older adults (FLUNITY-HD): an individual-level pooled analysis 0.17
Once-daily oral icotrokinra versus placebo and once-daily oral deucravacitinib in participants with moderate-to-severe plaque psoriasis (ICONIC-ADVANCE 1 & 2): two phase 3, randomised, placebo-controlled and active-comparator-controlled trials 0.47
Efficacy and safety of tirzepatide in children and adolescents with type 2 diabetes (SURPASS-PEDS): a randomised, double-blind, placebo-controlled, phase 3 trial 0.75
Influenza vaccination to improve outcomes for patients with acute heart failure (PANDA II): a multiregional, seasonal, hospital-based, cluster-randomised, controlled trial in China 0.06
Antisense oligonucleotide DGAT-2 inhibitor, ION224, for metabolic dysfunction-associated steatohepatitis (ION224-CS2): results of a 51-week, multicentre, randomised, double-blind, placebo-controlled, phase 2 trial 1.00
Safety and efficacy of once-weekly efruxifermin versus placebo in metabolic dysfunction-associated steatohepatitis (HARMONY): 96-week results from a multicentre, randomised, double-blind, placebo-controlled, phase 2b trial 0.94
Efficacy and safety of intravenous induction and subcutaneous maintenance therapy with guselkumab for patients with Crohn's disease (GALAXI-2 and GALAXI-3): 48-week results from two phase 3, randomised, placebo and active comparator-controlled, double-blind, triple-dummy trials 0.55
Estimating the effect of maternal viral load on perinatal and postnatal HIV transmission: a systematic review and meta-analysis 0.89
Prademagene zamikeracel for recessive dystrophic epidermolysis bullosa wounds (VIITAL): a two-centre, randomised, open-label, intrapatient-controlled phase 3 trial 1.00
Once-weekly insulin efsitora alfa versus once-daily insulin glargine U100 in adults with type 2 diabetes treated with basal and prandial insulin (QWINT-4): a phase 3, randomised, non-inferiority trial 0.67
Once-weekly insulin efsitora alfa versus once-daily insulin degludec in adults with type 2 diabetes currently treated with basal insulin (QWINT-3): a phase 3, randomised, non-inferiority trial 0.89
11 2.37
Safety, tolerability, pharmacokinetics, and efficacy of burosumab in infants with X-linked hypophosphataemia: an open-label, multicentre, non-randomised study 0.07
Risk of recurrence after successful surgery for Cushing's disease and association with USP8 genotype and tumour size: an international, retrospective, longitudinal cohort study 0.08
3 months vs 12 months of romosozumab for postmenopausal osteoporosis (LIDA): an open-label, non-inferiority, randomised controlled trial 1.00
Effect of surgical versus conservative management on cardiovascular outcomes in patients with bilateral adrenal tumours and cortisol excess: an international, retrospective cohort study 0.08
11th edition of the IDF Diabetes Atlas: global, regional, and national diabetes prevalence estimates for 2024 and projections for 2050 0.11
Cycle characterisation and clinical complications in patients with cyclic Cushing's syndrome: insights from an international retrospective cohort study 0.11
Once-weekly semaglutide 7·2 mg in adults with obesity and type 2 diabetes (STEP UP T2D): a randomised, controlled, phase 3b trial 0.43
Association of gestational thyroid function and thyroid autoimmunity with gestational diabetes: a systematic review and individual participant meta-analysis 0.18
Treatments for MEN1-associated endocrine tumours: three systematic reviews and a meta-analysis 0.11
Once‑weekly IcoSema versus once‑weekly insulin icodec in type 2 diabetes management (COMBINE 1): an open‑label, multicentre, treat‑to‑target, randomised, phase 3a trial 0.10
Once-weekly IcoSema versus multiple daily insulin injections in type 2 diabetes management (COMBINE 3): an open-label, multicentre, treat-to-target, non-inferiority, randomised, phase 3a trial 0.10
15 4.19
Adaptive intervention strategies for malaria vector control in western Kenya: a cluster, sequential, multiple-assignment, randomised, open-label trial 0.70
Effects of a peer-support lifestyle intervention on diabetes incidence in India (K-DPP): 9-year follow-up of a cluster-randomised, controlled trial 0.12
Strategies to reduce antimicrobial resistance in newborns in low-income and middle-income countries: a systematic review and meta-analysis 0.29
Evaluation of fluorometholone as adjunctive medical therapy for trachomatous trichiasis surgery (FLAME): a parallel, double-blind, randomised controlled field trial in the Jimma Zone, Ethiopia 0.39
Scaling an intervention for the engagement of people with HIV who inject drugs into care in Viet Nam: an implementation-effectiveness, cluster-randomised trial 0.43
Melioidosis in Mali: a retrospective observational study 0.09
Global antibiotic consumption and regional antimicrobial resistance, 2010–21: an analysis of pharmaceutical sales and antimicrobial resistance surveillance data 0.08
Screening for asymptomatic tuberculosis among adults with household exposure to pulmonary tuberculosis: a prospective observational cohort study 0.18
Medical oxygen service readiness and service coverage in seven countries in Africa and Asia: a cross-sectional survey and clinical audit 0.09
Guiding the development of the tuberculosis screening target product profile using single-screen and multi-screen approaches: a modelling study 0.04
Global variation in patient factors, interventions, and postoperative outcomes for those undergoing trauma laparotomy: an international, prospective, observational cohort study 0.05
Evidence-based decision making for malaria elimination applying the Freedom From Infection statistical framework in five malaria eliminating countries: an observational study 0.11
Prevalence, awareness, treatment, and control of diabetes in India: a nationally representative survey of adults aged 45 years and older 0.73
Clinical impact and cost-effectiveness of the WHO-recommended advanced HIV disease package of care 0.47
Protection from killed whole-cell cholera vaccines: a systematic review and meta-analysis 0.43
2 1.80
Herpes zoster vaccination and incident dementia in Canada: an analysis of natural experiments 0.80
Lifetime and 10-year absolute risk of cognitive impairment in relation to amyloid PET severity: a retrospective, longitudinal cohort study 1.00
11 2.77
Confirmatory efficacy and safety trial of magnetic seizure therapy versus right unilateral ultra-brief electroconvulsive therapy in depression (CREST–MST): a randomised, double-blind, non-inferiority trial in Canada and the USA 0.54
First-episode psychosis and substance use involvement across birth cohorts in Canada: a retrospective longitudinal population-based study 0.06
Life event trajectories and suicidal ideation throughout adolescence: a prospective cohort study from Germany, France, Ireland, and the UK 0.03
Joint detection of risk for psychotic disorders or bipolar disorders in clinical practice in the UK: development and validation of a clinical prediction model 0.08
Efficacy and safety of iclepertin for cognitive impairment associated with schizophrenia (CONNEX programme): results from three phase 3 randomised controlled trials 0.41
Transdiagnostic effectiveness and safety of clozapine in individuals with psychotic, affective, and personality disorders: nationwide and meta-analytic comparisons with other antipsychotics 0.04
The global epidemiology of personality disorder: a systematic review and meta-regression 0.22
The prevalence and estimated burden of somatoform disorders: a systematic review and meta-analysis of their epidemiology 0.17
Real-world effectiveness of clozapine augmentation with antidepressants: within-subject data evidence from two European nationwide cohorts 0.10
Absolute and relative risks of mental disorders in families: a Danish register-based study 0.13
Long-acting oral weekly risperidone (LYN-005) for schizophrenia in the USA (STARLYNG-1): a multicentre, open-label, non-randomised phase 3 trial 1.00
36 18.86
Decompression with or without Duraplasty for Chiari I and Syringomyelia 0.98
Prehospital Resuscitation with Type O Whole Blood for Trauma and Hemorrhage 0.94
Telitacicept for IgA Nephropathy — Interim Analysis of a Phase 3 Trial 0.13
Pulmonary Tuberculosis Detection with MiniDock MTB Using Swab Samples 0.25
Balanced Fluid or 0.9% Saline in Children Treated for Septic Shock 0.53
Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for Acute Pulmonary Embolism 0.41
Efficacy and Safety of Obinutuzumab in Active Systemic Lupus Erythematosus 0.28
Finerenone in Type 1 Diabetes and Chronic Kidney Disease 0.26
Hematopoietic Stem-Cell Gene Therapy for Cystinosis 0.90
Cabotegravir plus Rilpivirine for Persons with HIV and Adherence Challenges 0.94
Mental Health Outcomes in Children after Parental Firearm Injury 1.00
Cardiovascular Outcomes with Tirzepatide versus Dulaglutide in Type 2 Diabetes 0.52
Ketamine or Etomidate for Tracheal Intubation of Critically Ill Adults 1.00
Daily Mosnodenvir as Dengue Prophylaxis in a Controlled Human Infection Model 0.63
Sibeprenlimab in IgA Nephropathy — Interim Analysis of a Phase 3 Trial 0.13
A Phase 3 Trial of Atacicept in Patients with IgA Nephropathy 0.31
Oral Icotrokinra for Plaque Psoriasis in Adults and Adolescents 0.63
Safety and Immunogenicity of an rVSV Lassa Fever Vaccine Candidate 0.59
Common Diseases in Clinical Cohorts — Not Always What They Seem 0.87
Belzutifan for Advanced Pheochromocytoma or Paraganglioma 0.36
A Phase 3 Trial of Telitacicept for Systemic Lupus Erythematosus 0.09
Association of 2024–2025 Covid-19 Vaccine with Covid-19 Outcomes in U.S. Veterans 1.00
Randomized Trial of Targeted Indoor Spraying to Prevent Aedes-Borne Diseases 0.43
Nexiguran Ziclumeran Gene Editing in Hereditary ATTR with Polyneuropathy 0.67
Medications for Opioid Use Disorder in County Jails — Outcomes after Release 1.00
Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension 0.38
High-Dose Influenza Vaccine to Reduce Hospitalizations 0.08
High-Dose Influenza Vaccine Effectiveness against Hospitalization in Older Adults 0.08
Survival of Transplanted Allogeneic Beta Cells with No Immunosuppression 0.25
Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity 0.27
Weekly Fixed-Dose Insulin Efsitora in Type 2 Diabetes without Previous Insulin Therapy 1.00
Cagrilintide–Semaglutide in Adults with Overweight or Obesity and Type 2 Diabetes 0.30
Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes 0.85
A Randomized Trial of Acute Normovolemic Hemodilution in Cardiac Surgery 0.05
Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes 0.47
Adjuvant Cemiplimab or Placebo in High-Risk Cutaneous Squamous-Cell Carcinoma 0.30
1 1.00
What Drives Risky Prescription Opioid Use? Evidence From Migration 1.00
1 1.00
Trauma at School: The Impacts of Shootings on Students’ Human Capital and Economic Outcomes 1.00
4 2.47
Guideline-based prognostic factors associated with mortality in pulmonary embolism: a systematic review and meta-analysis 0.08
Shape-sensing robotic-assisted bronchoscopy with integrated mobile cone-beam CT for small nodules: results from the prospective multicentre CONFIRM study 1.00
Generalisability of ARDS biological subphenotype models in Asians: an international, multicentre, prospective biomarker study 0.39
Efficacy of fentanyl buccal tablet and morphine for exertional dyspnoea in patients with cancer: a double-blind, placebo-controlled, randomised clinical trial 1.00
6 2.86
The Potential Role of Wastewater Surveillance Signals for Overdose Prevention in Marin County, California, February 2023–June 2024 1.00
Wastewater surveillance of dengue and chikungunya during the worst arbovirus epidemic in Brazil 0.25
Metatranscriptomics Reveals System-Specific Viral Adaptive Strategies and Prokaryotic Defense Trade-offs Across Anaerobic Digestion Systems 0.11
L-norepinephrine induces community shift, oxidative stress response, metabolic reprogramming, and virulence potential in wastewater microbiomes 0.17
Assessment of Endocrine-Disrupting Chemicals in Bottled Water: A Cross-Sectional Study in Algiers and risk assessment in pregnant women 0.33
Predicting Naegleria fowleri Freshwater Habitat Suitability in the United States for the Present-Day and Future using Ecological Niche Modeling 1.00

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