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Rand et al. reply

David G. Rand
Joshua D. Greene
Martin A. Nowak
Research05 Jun 2013
Nature

Volume: 498, P: E2-E3
Developmental convergence and divergence in human stem cell models of autism

Risk associated with genetically defined forms of autism spectrum disorder (ASD) can propagate by means of transcriptional regulation to affect convergently dysregulated pathways, providing insight into the convergent impact of ASD genetic risk on human neurodevelopment.

Aaron Gordon
Se-Jin Yoon
Daniel H. Geschwind
ResearchOpen Access29 Jan 2026
Nature

P: 1-13
The empirical structure of psychopathology is represented in large language models

This study applies large language models (LLMs) to analyze language used for the description of psychopathology across clinical questionnaires and uses empirical data from four large-scale datasets. The authors find that the empirical structure of psychopathology is well represented in LLMs.

Joseph Kambeitz
Jason Schiffman
Kai Vogeley
ResearchOpen Access18 Nov 2025
Nature Mental Health

Volume: 3, P: 1482-1492
Dr. R. F Rand

A. B. RENDLE
Comments & Opinion27 Feb 1937
Nature

Volume: 139, P: 359
Lithospheric models supported by the Caribbean and Levant examples help rethink transpression at plate boundaries

The study shows how inherited weak zones determine whether transpression produces pushups, duplexes, or parallel faults. 3D models offer insights into the deep processes that drive deformation and seismic patterns in the Caribbean and Levant.

Anthony Jourdon
Laetitia Le Pourhiet
Alice-Agnes Gabriel
ResearchOpen Access06 Jan 2026
Nature Communications

Volume: 17, P: 1-17
Full-parametric, transdimensional, and joint inversion of surface wave dispersion and earthquake-based HVSR by MBMO for obtaining reliable subsurface structures

Hanbing Ai
Kamal Abdelrahman
Ahmed M. Eldosouky
ResearchOpen Access01 Feb 2026
Scientific Reports

Volume: 16, P: 1-31
Senotoxins target senescence via lipid binding specificity, ion imbalance and lipidome remodeling

Moral-Sanz, Fernández-Carrasco and colleagues identify senolytic properties of sea anemone-derived pore-forming toxins, with selectivity mediated by senescence-associated lipid profiles. An optimized senotoxin improves the efficacy of chemotherapy in mouse models.

Javier Moral-Sanz
Isabel Fernández-Carrasco
Maria P. Ikonomopoulou
ResearchOpen Access12 Jan 2026
Nature Aging

P: 1-19
Ultra-high-throughput mapping of genetic design space

CLASSIC is a high-throughput genetic profiling platform that combines long- and short-read next-generation-sequencing modalities to quantitatively assess pools of constructs of arbitrary length containing diverse genetic part compositions.

Kshitij Rai
Ronan W. O’Connell
Caleb J. Bashor
Research14 Jan 2026
Nature

P: 1-10
Natural Irradiation Damage in Ivory Coast Diamonds

H. O. A. MEYER
H. J. MILLEDGE
E. NAVE
Research01 Apr 1965
Nature

Volume: 206, P: 392
Measuring central charge on a universal quantum processor

Central charge, a key quantity in conformal field theories, is crucial in the study of critical phenomena, yet its measurement has remained elusive. Here, the authors extract the central charge of several quantum critical models by accurately preparing their ground states on a superconducting quantum processor.

Nazlı Uğur Köylüoğlu
Swarnadeep Majumder
Khadijeh Najafi
ResearchOpen Access08 Jan 2026
Nature Communications

Volume: 17, P: 1-8
Inference on inner galaxy structure via gravitational waves from supermassive binaries

The lowest-frequency gravitational wave background may be shaped by supermassive black hole binaries that scatter nearby stars or dark matter. In this case, the NANOGrav 15-year dataset favours dense galactic centres with 10⁶ solar masses per cubic parsec.

Yifan Chen
Matthias Daniel
Olivia Young
Research05 Feb 2026
Nature Astronomy

P: 1-10
Age-related constraints on the spatial geometry of the brain

As we age, our brains don’t just shrink, their entire geometry changes. This study links specific patterns of brain expansion and compression to cognitive impairment, revealing a new way to understand age-related decline.

Yuritza Y. Escalante
Jenna N. Adams
Niels Janssen
ResearchOpen Access29 Sept 2025
Nature Communications

Volume: 16, P: 1-14
Environmental conditions associated with initial northern expansion of anatomically modern humans

Past global human migration was the result of environmental and cultural factors. Here, the authors develop a statistical approach that combines archaeological, genetic, and palaeoclimate data to identify regional environmental conditions facilitating population expansion routes in northern Eurasia and the Americas.

Frédérik Saltré
Joël Chadœuf
Corey J. A. Bradshaw
ResearchOpen Access22 May 2024
Nature Communications

Volume: 15, P: 1-12
Solid oxide fuel cell simulation model tuning using operating conditions dependent optimization techniques

Haya Hesham
Mohamed Abdel Rahman
Nourhan M. Elbehairy
ResearchOpen Access28 Jan 2026
Scientific Reports

Volume: 16, P: 1-23
Interpretable inflammation landscape of circulating immune cells

Including data from 1,047 patients across 19 inflammatory diseases, a new atlas presents a comprehensive model of inflammation in circulating immune cells.

Laura Jiménez-Gracia
Davide Maspero
Holger Heyn
ResearchOpen Access12 Jan 2026
Nature Medicine

P: 1-12
Enhancing classification accuracy in medical datasets using a hybrid distance and cluster refinement-based K-means clustering method

Hussein A. A. Al-Khamees
Mudatheer M. Al-Slivani
Mohd Aliff Afira Sani
ResearchOpen Access25 Jan 2026
Scientific Reports

Volume: 16, P: 1-25
Enhanced spatial clustering of single-molecule localizations with graph neural networks

Single-molecule localisation microscopy enables nanoscale mapping of molecular organisation, but clustering stochastic data remains challenging. Here, authors present a graph neural network method that enhances clustering across complex biological datasets.

Jesús Pineda
Sergi Masó-Orriols
Carlo Manzo
ResearchOpen Access03 Nov 2025
Nature Communications

Volume: 16, P: 1-17
Secure dynamic multiparty quantum private comparison

Hussein Abulkasim
Ahmed Farouk
Shohini Ghose
ResearchOpen Access28 Nov 2019
Scientific Reports

Volume: 9, P: 1-16
Benchmarking machine learning methods for synthetic lethality prediction in cancer

A comprehensive benchmarking of existing synthetic lethality (SL) prediction methods is lacking. Here, the authors compare 12 recently developed machine learning methods for SL prediction, assess their performance, and provide guidance on the selection of the most suitable method.

Yimiao Feng
Yahui Long
Jie Zheng
ResearchOpen Access20 Oct 2024
Nature Communications

Volume: 15, P: 1-14
Revealing a coherent cell-state landscape across single-cell datasets with CONCORD

CONCORD generates denoised cell encodings that preserve key biological structures in single-cell datasets.

Qin Zhu
Zuzhi Jiang
Zev J. Gartner
ResearchOpen Access05 Jan 2026
Nature Biotechnology

P: 1-15
Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders

How neurodevelopmental disorder-associated risk genes are translated into spatially patterned brain vulnerabilities is unclear. Here, the authors show that disorder-specific patterns of neuroanatomical changes are aligned to brain expression maps of disease risk genes in healthy subjects.

Jakob Seidlitz
Ajay Nadig
Armin Raznahan
ResearchOpen Access03 Jul 2020
Nature Communications

Volume: 11, P: 1-14
Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression

Epilepsy is a brain network disorder with associated genetic risk factors. Here, the authors show that spatial patterns of transcriptomic vulnerability co-vary with structural brain network alterations in focal and generalized epilepsy.

Sara Larivière
Jessica Royer
Boris C. Bernhardt
ResearchOpen Access27 Jul 2022
Nature Communications

Volume: 13, P: 1-16
Hybrid Fennec Fox–Sand Cat optimized cascaded ANFIS MPPT for enhanced control of DFIG-based WECS with grid support

Prashanth Rajanala
Malligunta Kiran Kumar
Ahmed Emara
ResearchOpen Access13 Dec 2025
Scientific Reports

Volume: 16, P: 1-20
Immunochromatographic Partition of Soluble Antigens on Columns of Insoluble Diazo-Gamma-Globulins

S. DeCARVALHO
A. J. LEWIS
J. R. UHRICK
Research01 Oct 1964
Nature

Volume: 204, P: 265-266
Dynamic energy-based multilayer routing framework for scalable and reliable IoT networks

Mehdi Hosseinzadeh
Amir Haider
Jan Lansky
ResearchOpen Access08 Jan 2026
Scientific Reports

Volume: 16, P: 1-22
Multi-omic definition of metabolic obesity through adipose tissue–microbiome interactions

Metabolomics, metagenomics, proteins and genetics were combined with clinical data to define a metabolic signature of obesity.

Rima M. Chakaroun
Meenakshi Pradhan
Fredrik Bäckhed
ResearchOpen Access02 Jan 2026
Nature Medicine

Volume: 32, P: 113-125
Secondary analysis of a randomised controlled trial on reducing sedentary behaviour and its effects on quality of life and wellbeing

Jooa Norha
Tanja Sjöros
Ilkka H. A. Heinonen
ResearchOpen Access22 Oct 2025
Scientific Reports

Volume: 15, P: 1-11
A systematic review and meta-analysis of disease clusters in multimorbidity

There is a growing body of research on disease clusters in multimorbidity, necessitating a systematic review and meta-analysis of methods and findings. Here, the authors show the range of methods applied, and identify six disease clusters with moderate stability across the multimorbidity literature.

Jennifer K. Ferris
Lean K. Fiedeldey
Andrew Wister
ResearchOpen Access26 Dec 2025
Nature Communications

Volume: 17, P: 1-15
Optimized model of microbial fuel cell using AI-driven walrus optimization algorithm

Motab Turki Almousa
Mohamed Louzazni
ResearchOpen Access07 Jan 2026
Scientific Reports

Volume: 16, P: 1-13
Dense, continuous membrane labeling and expansion microscopy visualization of ultrastructure in tissues

Lipid membranes are hard to visualise in tissues with nanoscale precision. The authors report ultrastructural membrane expansion microscopy (umExM), a tool that enables dense membrane labelling for nanoscale imaging of cellular membranes using a standard confocal microscope.

Tay Won Shin
Hao Wang
Edward S. Boyden
ResearchOpen Access12 Feb 2025
Nature Communications

Volume: 16, P: 1-17
Reversible Changes in Shape of Red Cells in Electrical Fields

R. P. RAND
A. C. BURTON
P. CANHAM
Research01 Mar 1965
Nature

Volume: 205, P: 977-978
A hybrid fuzzy-PIDD² control strategy for coordinated LFC and AVR in renewable-integrated multi-area power systems

Mohamed H. T. Omar
Ragi A. Hamdy
Hossam Kotb
ResearchOpen Access27 Jan 2026
Scientific Reports

Volume: 16, P: 1-42
A multi-strategy improved lemur optimiser for global optimisation and engineering applications

Mingjia Li
Dexin Sun
Jing Xu
ResearchOpen Access28 Nov 2025
Scientific Reports

Volume: 15, P: 1-28
Machine learning enables scalable and systematic hierarchical virus taxonomy

vConTACT3 enables multirank, large-scale classification of eukaryotic and prokaryotic viruses.

Benjamin Bolduc
Olivier Zablocki
Matthew B. Sullivan
Research19 Dec 2025
Nature Biotechnology

P: 1-10
Natural history and the rogue elephant

A.J. Cain
Books & Arts01 Dec 1983
Nature

Volume: 306, P: 506-507
Plasmon-enhanced ultralow-threshold solid-state triplet fusion upconversion

Performance of solid-state triplet fusion upconversion films is enhanced by surface plasmons, intensity threshold is reduced by a factor of 17 and external quantum efficiency is enhanced by a factor of 19. A white-emitting organic light-emitting diode featuring upconverted blue emission—rather than blue electroluminescence—is demonstrated, with a colour rendering index of up to 86.2.

Jesse A. Wisch
Kelvin A. Green
Barry P. Rand
Research24 Oct 2025
Nature Photonics

Volume: 20, P: 24-30
Does AI already have human-level intelligence? The evidence is clear

The vision of human-level machine intelligence laid out by Alan Turing in the 1950s is now a reality. Eyes unclouded by dread or hype will help us to prepare for what comes next.

Eddy Keming Chen
Mikhail Belkin
David Danks
Comments & Opinion02 Feb 2026
Nature

Volume: 650, P: 36-40
Robust load frequency control in renewable integrated Multi Area grids using hybrid SA and QIO tuned PIDF controller

Waqar Younis
Muhammad Zubair Yameen
Muhammad Khalid
ResearchOpen Access22 Oct 2025
Scientific Reports

Volume: 15, P: 1-32
An integration of deep learning models for effective classification of human activity patterns in disabled people using gesture analysis

Hend Khalid Alkahtani
Nouf Al-Kahtani
Radwa Marzouk
ResearchOpen Access12 Dec 2025
Scientific Reports

Volume: 15, P: 1-13
Optimization of automatic generation controllers in renewable multi-area power systems using the Fata Morgana algorithm

Aykut Fatih Güven
Erdinç Şahin
Viktoriia Bereznychenko
ResearchOpen Access08 Dec 2025
Scientific Reports

Volume: 15, P: 1-34
Gene therapy delivery of anti-Müllerian hormone in prepubertal female domestic cats induces long-term sterilization

Surgical sterilization alone cannot control global stray and feral domestic cat populations. Here, Godin et al. show that a single-dose injectable female sterilant administered before puberty safely and completely prevents pregnancy after maturity.

Philippe Godin
Nicholas Nagykery
David Pépin
ResearchOpen Access28 Nov 2025
Nature Communications

Volume: 16, P: 1-15
ProFlex as a linguistic bridge for decoding protein dynamics in normal mode analysis

In this work the authors present an approach called ProFlex which compresses flexibility information from protein structures via normal mode analysis, enabling scalable insights into protein dynamics and function through a novel structural alphabet.

Damian J. Magill
Timofey A. Skvortsov
ResearchOpen Access13 Oct 2025
Nature Communications

Volume: 16, P: 1-12
RNN based SVPWM controlled grid integrated PV system with COA based MPPT for enhanced power quality and dynamic tracking

Ankathi Manjula
A. Ramesh Babu
ResearchOpen Access03 Nov 2025
Scientific Reports

Volume: 15, P: 1-40
An innovative metaheuristic algorithm for photovoltaic tilt angle optimization

Lingqi He
Bin Zhao
Li Wang
ResearchOpen Access07 Dec 2025
Scientific Reports

Volume: 15, P: 1-33
Heterogeneity-preserving discriminative feature selection for disease-specific subtype discovery

Complex diseases often involve subtle subtypes, making their detection vital for personalized medicine. Here, the authors show that the PHet (Preserving Heterogeneity) method reliably uncovers disease-specific subtypes using small sets of features

Abdur Rahman M. A. Basher
Caleb Hallinan
Kwonmoo Lee
ResearchOpen Access16 Apr 2025
Nature Communications

Volume: 16, P: 1-25
A memorized multi-objective Sinh-Cosh optimizer for solving multi-objective engineering design problems

Doaa El-Nagar
Ibrahim Zeidan
Mohamed Issa
ResearchOpen Access21 Jan 2026
Scientific Reports

Volume: 16, P: 1-40
Deep reinforcement learning for resource allocation and scalable numerology in NR-U enabled multi-RAT HetNets

Noha A. Elmosilhy
Mahmoud M. Elmesalawy
Ibrahim I. Ibrahim
ResearchOpen Access03 Feb 2026
Scientific Reports

Volume: 16, P: 1-21
Global health diagnostics

An essential component of evaluating and improving global health is access to appropriate diagnostic tools. Through this series of papers we hope to further the dissemination of current knowledge on global health diagnostic needs for the conditions that most severely affect those living in the developing world.

Deborah C. Hay Burgess
Jeffrey Wasserman
Carol A. Dahl
Research22 Nov 2006
Nature

Volume: 444, P: 1-2
Prevalence, types, and demographic characteristics associated with major life changes following psychedelic use

Nicholas A. Carlisle
Otto Simonsson
Peter S. Hendricks
ResearchOpen Access28 Jan 2026
Scientific Reports

P: 1-11
Scalable 3D reconstruction for X-ray single particle imaging with online machine learning

The authors devise an algorithm to reconstruct proteins from X-ray single particle data, unlocking the ability to process datasets online, in a single pass. The technique matches or outperforms existing methods in simulation and on experimental data.

Jay Shenoy
Axel Levy
Gordon Wetzstein
ResearchOpen Access24 Jul 2025
Nature Communications

Volume: 16, P: 1-10

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