Nature Search

Multiple self–healing squamous epitheliomata (ESS1) mapped to chromosome 9q22–q31 in families with common ancestry

David R. Goudie
Martin A.R. Yuille
Malcolm A. Ferguson-Smith
Research01 Feb 1993
Nature Genetics

Volume: 3, P: 165-169
The Very Rev. Sir George Adam Smith, F.B.A

A. SOUTER
Comments & Opinion09 May 1942
Nature

Volume: 149, P: 519-520
Simulating topological order on quantum processors

Topological phases in quantum many-body systems emerge from long-range entanglement rather than symmetry breaking, giving rise to properties such as topology-dependent degeneracy, protected edge modes and anyonic excitations. This Review discusses recent advances on how to realize and study such interacting topological states on digital quantum computers.

Adam Gammon-Smith
Michael Knap
Frank Pollmann
Reviews26 Jan 2026
Nature Reviews Physics

P: 1-11
Mosquito sex separation using complementation of selectable traits and engineered neo-sex chromosomes

Releasing only males remains a major hurdle for mosquito genetic control. Here, authors develop a mosquito strain using CRISPR and a synthetic sex chromosome, producing dark males and yellow females that develop slower and lay desiccation-sensitive eggs, enabling easy separation and safe releases.

Doron S. Y. Zaada
Or Toren
Philippos A. Papathanos
ResearchOpen Access11 Dec 2025
Nature Communications

Volume: 16, P: 1-15
Programmable 200 GOPS Hopfield-inspired photonic Ising machine

An architecture inspired by Hopfield networks based on a programmable, stable, room-temperature optoelectronic oscillator-based photonics Ising machine is introduced that can be used to efficiently address optimization and combinatorics problems.

Nayem Al-Kayed
Charles St-Arnault
Bhavin J. Shastri
Research17 Dec 2025
Nature

Volume: 648, P: 576-584
Thomas Cavalier-Smith (1942–2021)

Polymath of cellular evolution who shaped understanding of the tree of life.

Thomas Richards
Comments & Opinion10 May 2021
Nature

Volume: 593, P: 190
Enhancing kinase-inhibitor activity and selectivity prediction through contrastive learning

MMCLKin is a multimodal and multiscale contrastive learning framework for kinase-inhibitor affinity prediction, kinase inhibitor selectivity profiling, virtual screening for known, unknown, and mutated kinases, and interpretable analysis.

Yanan Tian
Ruiqiang Lu
Huanxiang Liu
ResearchOpen Access03 Dec 2025
Nature Communications

Volume: 16, P: 1-22
Structural basis of Nuclear Factor 1-X DNA recognition provides prototypic insight into the NFI family

The Nuclear Factor I (NFI) family includes transcription factors key to development, cancer, and genetic disorders. Here, the authors present the structure and DNA-binding properties of NFI-X, a prototype for the entire NFI family.

Michele Tiberi
Michela Lapi
Marco Nardini
ResearchOpen Access19 Nov 2025
Nature Communications

Volume: 16, P: 1-14
Gonadal Growth in Chick Embryos

URSULA MITTWOCH
T. LAKSHMI NARAYANAN
C. A. B. SMITH
Research16 Jun 1971
Nature New Biology

Volume: 231, P: 197-200
Investigating the neuronal role of the proteasomal ATPase subunit gene PSMC5 in neurodevelopmental proteasomopathies

Variants in the PSMC5 gene impair proteasome function and cellular homeostasis, altering brain development in children. This study reveals underlying molecular mechanisms contributing to this neurodevelopmental phenotype, and suggests therapeutic leads for neurodevelopmental proteasomopathies.

Sébastien Küry
Janelle E. Stanton
Elke Krüger
ResearchOpen Access26 Nov 2025
Nature Communications

Volume: 16, P: 1-21
3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets

Amanda Birmingham
Emily M Anderson
Anastasia Khvorova
Research17 Feb 2006
Nature Methods

Volume: 3, P: 199-204
Dynamic observation of defect annealing in CdTe at lattice resolution

R. Sinclair
F. A. Ponce
C. J. D. Catto
Research08 Jul 1982
Nature

Volume: 298, P: 127-131
Pesticides and habitat loss additively reduce wild bees in crop fields

The authors synthesize bee assemblage data from 681 crop fields across three continents, finding that local pesticide hazards and decreasing adjacent semi-natural habitats both negatively affected wild bee abundance and species richness in crop fields, while pesticides also reduced functional diversity.

Anina Knauer
Subodh Adhikari
Matthias Albrecht
ResearchOpen Access10 Dec 2025
Nature Ecology & Evolution

Volume: 10, P: 95-104
Pressure-tuned plethora of ferroelectric phases in CuInP₂S₆

Sambridhi Shah
Pegah Mohammadi
Janice L. Musfeldt
ResearchOpen Access17 Jan 2026
npj 2D Materials and Applications

P: 1-10
Contrasting pathways to tree longevity in gymnosperms and angiosperms

Tree longevity is thought to increase in harsh environments, but global evidence of drivers is lacking. Here, the authors find two different pathways for tree longevity: slow growth in resource limited environments and increasing tree stature and/or slow growth in competitive environments.

Roel J. W. Brienen
Giuliano Maselli Locosselli
Chunyu Zhang
ResearchOpen Access19 Dec 2025
Nature Communications

Volume: 17, P: 1-14
George Smith

A. H. SAYCE
News14 Sept 1876
Nature

Volume: 14, P: 421-422
National Academies report has broad support

Paul Vincelli
Douglas Jackson-Smith
Susan Weller
Correspondence11 Apr 2017
Nature Biotechnology

Volume: 35, P: 304-306
Transcriptomic profiling and machine learning uncover gene signatures of psoriasis endotypes and disease severity

Rider, Grantham, Smith, Watson et al. integrate multiomic data from patients with psoriasis using dimensionality reduction and machine learning techniques. This approach identifies biological relationships between genetic background, clinical features and disease severity, providing insight into disease variability across individuals.

Ashley Rider
Henry J. Grantham
Paola Di Meglio
ResearchOpen Access21 Jan 2026
Communications Medicine

Volume: 6, P: 1-21
Wallace Smith Broecker (1931-2019)

Geochemist who transformed understanding of the climate system.

Peter de Menocal
Comments & Opinion26 Mar 2019
Nature

Volume: 568, P: 34
Disruption of the oak tree microbiome with urbanization

Urbanization disrupts oak tree microbiomes by reducing beneficial fungi and increasing plant and human pathogens across leaves, roots and soils, with consequences for tree health, urban climate mitigation and potential human exposure to pathogens.

Kathryn F. Atherton
Chikae Tatsumi
Jennifer M. Bhatnagar
Research03 Oct 2025
Nature Cities

Volume: 2, P: 958-968
Early favorable prostate-specific antigen response prediction in metastatic hormone sensitive prostate cancer

There is a need for an easy-to-use clinical tool, that could predict favorable early PSA response and subsequently enhance early risk stratification, as well as guide treatment planning. Here, the authors show that based on patient data from four phase III randomized trials, Nadir androgen receptor pathway inhibitor (APRI)- Derived Integrative Response (NADIR) model predicts favorable early PSA response to ≤0.2 ng/mL by 6 months in metastatic hormone sensitive prostate cancer (mHSPC) patients initiating treatment with an APRI.

Soumyajit Roy
Yilun Sun
Daniel E. Spratt
ResearchOpen Access17 Dec 2025
Nature Communications

Volume: 17, P: 1-10
Evolution of promoter-proximal pausing enabled a new layer of transcription control

Here, the authors generated and analyzed run-on sequencing data to observe transcription in species across the tree of life to uncover the origins of the promoter-proximal pause.

Alexandra G. Chivu
Brent A. Basso
Charles G. Danko
Research15 Dec 2025
Nature Structural & Molecular Biology

P: 1-11
Factor Dependent Binding of Methionyl-tRNAs to Reticulocyte Ribosomes

DAVID A. SHAFRITZ
W. FRENCH ANDERSON
Research29 Aug 1970
Nature

Volume: 227, P: 918-920
Linear Polarization in Pulsating Radio Sources

A. G. LYNE
F. G. SMITH
Research13 Apr 1968
Nature

Volume: 218, P: 124-126
A bothy among the stars

Just passing through.

M. J. Pettit
Comments & Opinion03 Dec 2025
Nature
Prof. E. Barclay-Smith

A. J. E. CAVE
Comments & Opinion04 Aug 1945
Nature

Volume: 156, P: 136-137
Prof. S. W. J. Smith, F.R.S

M. L. OLIPHANT
A. A. DEE
Comments & Opinion02 Oct 1948
Nature

Volume: 162, P: 519-520
Deterrent Effect of Insecticides on Malaria Vectors

A. SMITH
Research30 Nov 1963
Nature

Volume: 200, P: 861-862
Dewey Smith and the meaning of All

Physics in action.

Robert Reed
Comments & Opinion22 Oct 2008
Nature

Volume: 455, P: 1148
Isolation of a gene from Drosophila by complementation in yeast

Steven Henikoff
Kelly Tatchell
Kim A. Nasmyth
Research01 Jan 1981
Nature

Volume: 289, P: 33-37
Dr. Marian W. Smith

A. E. MOURANT
Comments & Opinion09 Dec 1961
Nature

Volume: 192, P: 917
Cascades of effectiveness of next-generation insecticide-treated nets against malaria, from entomological trials to real-life conditions

Insecticide resistance can limit the effectiveness of insecticide-treated nets for malaria prevention, but other factors such as access and durability also contribute. Here, the authors quantify impacts of this ‘cascade’ of factors using a mathematical model.

Clara Champagne
Jeanne Lemant
Emilie Pothin
ResearchOpen Access16 Dec 2025
Nature Communications

Volume: 16, P: 1-16
Extracellular matrix proteolysis maintains synapse plasticity during brain development

This study demonstrates that the extracellular matrix (ECM) of the developing brain stabilizes recently born synapses. The authors identify a microglial metalloprotease that digests the ECM to increase the plasticity of these newborn synapses.

Haruna Nakajo
Ran Cao
Anna V. Molofsky
ResearchOpen Access22 Dec 2025
Nature Neuroscience

P: 1-14
The Ancestors of the Eutheria

A. A. ABBIE
Research16 Sept 1939
Nature

Volume: 144, P: 523-524
Biosynthetic Labelling of Mammalian Insulins in vitro

K. W. TAYLOR
D. G. PARRY
G. HOWARD SMITH
Research12 Sept 1964
Nature

Volume: 203, P: 1144-1145
Structure of Vitamin B₁₂ : The Structure of Vitamin B₁₂ and its Hexacarboxylic Acid Degradation Product

R. BONNETT
J. R. CANNON
E. LESTER SMITH
Research20 Aug 1955
Nature

Volume: 176, P: 328-330
William Smith (1769–1839), The Father of English Geology

V. A. E.
News26 Aug 1939
Nature

Volume: 144, P: 354-355
Elliot Smith Commemorated

News & Views24 Nov 1972
Nature

Volume: 240, P: 180
X-ray-diffraction and electrical-transport imaging of superconducting superhydride (La,Y)H₁₀

The authors report the synthesis of (La_0.9Y_0.1)H₁₀ superhydrides and their characterization using synchrotron-based, spatially resolved x-ray diffraction and electrical transport imaging. They reveal μm-scale structural inhomogeneity with coexisting cubic and hexagonal clathrate phases exhibiting distinct superconducting transition temperatures.

Abdul Haseeb Manayil Marathamkottil
Kui Wang
Russell J. Hemley
ResearchOpen Access18 Dec 2025
Nature Communications

Volume: 16, P: 1-9
William Smith: His Maps and Memoirs

G. A. J. C.
Books & Arts30 Sept 1920
Nature

Volume: 106, P: 144
Implications of Similarity in Rare-Earth Fractionation of Nakhlitic Meteorites and Terrestrial Basalts

R. A. SCHMITT
R. H. SMITH
Research10 Aug 1963
Nature

Volume: 199, P: 550-552
Interaction of small and extended defects in nonstoichiometric oxides

L. A. Bursill
David J. Smith
Research24 May 1984
Nature

Volume: 309, P: 319-321
Correlation Between Unit Activity and Slow Potential Changes in the Unanaesthetized Cerebral Cortex of the Cat

A. D. J. ROBERTSON
Research20 Nov 1965
Nature

Volume: 208, P: 757-758
Prof. J. Lorrain Smith, F.R.S

A. E. B.
Comments & Opinion23 May 1931
Nature

Volume: 127, P: 787
Initiator Codons in Eukaryotes

J. C. BROWN
A. E. SMITH
Research16 May 1970
Nature

Volume: 226, P: 610-612
Urea Excretion in Ruminants

H. G. LIVINGSTON
W. J. A. PAYNE
M. T. FRIEND
Research16 Jun 1962
Nature

Volume: 194, P: 1057-1058
APOBEC3 promotes squamous differentiation via IL-1A/AP-1 signaling

Deaminases of the APOBEC3 family contribute to the mutagenesis of various cancers, including urothelial carcinoma (UC) of the bladder. Here, the authors use functional studies and transcriptomics to demonstrate that APOBEC3 promotes tumour progression and squamous trans-differentiation in UC through IL-1α and downstream activation of the AP-1 transcription factor.

Michael S. Sturdivant
Andrew S. Truong
William Y. Kim
ResearchOpen Access14 Dec 2025
Nature Communications

Volume: 17, P: 1-18
Evaluating transportability of in vitro cellular models to in vivo human phenotypes using gene perturbation data

The extent to which in-vitro cellular experiments are effective models for complex biology underlying human phenotypes is often unclear. Here the authors propose and implement a framework using gene perturbation data to evaluate in-vitro models.

Laurence J. Howe
Yurii S. Aulchenko
Adrian Cortes
ResearchOpen Access13 Dec 2025
Nature Communications

Volume: 17, P: 1-13
Intrathecal onasemnogene abeparvovec in treatment-naive patients with spinal muscular atrophy: a phase 3, randomized controlled trial

The phase 3 STEER trial showed that a single intrathecal dose of onasemnogene abeparvovec significantly improved motor function in children and adolescents with spinal muscular atrophy versus sham, with a similar and acceptable safety profile.

Crystal M. Proud
Dũng Chí Vũ
Yuh-Jyh Jong
ResearchOpen Access08 Dec 2025
Nature Medicine

P: 1-7
A genome-wide association study of mass spectrometry proteomics using a nanoparticle enrichment platform

Genome-wide association analyses of blood plasma samples using a mass spectrometry-based platform illustrate the complementarity of different proteomics approaches for identifying protein quantitative trait loci.

Karsten Suhre
Qingwen Chen
Jessica A. Lasky-Su
ResearchOpen Access27 Nov 2025
Nature Genetics

Volume: 57, P: 2987-2996

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