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Showing 1–50 of 2598 results

Advanced filters: Author: Pamela A. Were Clear advanced filters

Pamela Sklar (1959–2017)

Psychiatrist who sought the genetic roots of mental illness.

Mark Daly
Comments & Opinion30 Jan 2018
Nature

Volume: 554, P: 32
A catalogue of early diverged contemporary human genome variation reveals distinct Khoe-San populations

By generating whole genomes of 150 participants representing 12 Khoe-San click-speaking groups, the authors, reveal over 1.3 million unknown DNA variants, distinct San and here described Damara genetic trajectories, while achieving century-long global predominance.

Weerachai Jaratlerdsiri
Pamela X. Y. Soh
Vanessa M. Hayes
ResearchOpen Access10 Feb 2026
Nature Communications

P: 1-17
Randomized unconditional cash transfers improved diet quantity and quality in a low-income community in Massachusetts, USA

In a randomized experiment in Chelsea, Massachusetts, USA, lower-income individuals who received cash transfers reduced calorie deficits and increased consumption of nutrient-dense, higher-cost foods. Their findings highlight the critical role that income support may have in a high-income country to reduce hunger.

Matthew M. Lee
Erica L. Kenney
Jeffrey Liebman
Research13 Feb 2026
Nature Food

P: 1-11
Reduced methane emissions in transgenic rice genotypes are associated with altered rhizosphere microbial hydrogen cycling

Rice paddies contribute to atmospheric methane (CH₄) levels. Here the authors show that increasing levels of the rice plant hormone PSY can reduce CH₄ emissions by over 50% via alteration of microbial H₂ cycling in the rhizosphere.

Ling-Dong Shi
Maria Florencia Ercoli
Jillian F. Banfield
ResearchOpen Access26 Jan 2026
Nature Communications

P: 1-19
Global multi-ancestry genome-wide analyses identify genes and biological pathways associated with thyroid cancer and benign thyroid diseases

Genome-wide association analyses using data from 19 biobanks identify variants influencing risk of thyroid diseases and yield polygenic risk scores associated with features of aggressive thyroid cancer.

Samantha L. White
Maizy S. Brasher
Nikita Pozdeyev
ResearchOpen Access05 Feb 2026
Nature Genetics

Volume: 58, P: 307-316
Identification of a potent V3 glycan site broadly neutralizing antibody targeting an N332_gp120 glycan-independent epitope

An anti-HIV-1 antibody that targets an N332_gp120 glycan-independent V3 epitope, a site of Env vulnerability, can decline viremia in HIV-1-infected humanized mice while overcoming classical V3 escape mutations.

Lutz Gieselmann
Andrew T. DeLaitsch
Florian Klein
ResearchOpen Access03 Feb 2026
Nature Immunology

P: 1-14
Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site

Crystal structures of HIV Env trimer with native glycosylation in complex with neutralizing antibodies reveal a glycan shield of high-mannose and complex-type N-glycan and indicate a path for germline-targeting vaccine design.

Harry B Gristick
Lotta von Boehmer
Pamela J Bjorkman
Research12 Sept 2016
Nature Structural & Molecular Biology

Volume: 23, P: 906-915
A split biotin ligase approach reveals proteins associated with oligomeric alpha-synuclein during aggregation

Analiese R. Fernandes
Abigail P. Owen
Pamela J. McLean
ResearchOpen Access04 Feb 2026
Scientific Reports

P: 1-14
Factors Affecting the Vernal Phytoplankton Outburst in the English Channel

W. R. G. ATKINS
PAMELA G. JENKINS
Research30 Jun 1956
Nature

Volume: 177, P: 1218-1219
Clinical validation of a tissue-agnostic genome-wide methylome enrichment assay to monitor response to pembrolizumab

Eric Y. Stutheit-Zhao
Yongqi Zhong
Enrique Sanz-Garcia
ResearchOpen Access13 Feb 2026
npj Precision Oncology

P: 1-10
Author Correction: Malaria trends in Ethiopian highlands track the 2000 ‘slowdown’ in global warming

Xavier Rodó
Pamela P. Martinez
Mercedes Pascual
Amendments and CorrectionsOpen Access13 Feb 2026
Nature Communications

Volume: 17, P: 1
A multidimensional workflow profiling of allogeneic virus-specific T cell therapies reveals potency-linked signatures

Allogeneic T cell therapies could be used in therapeutic applications because of their potential for ‘off-the-shelf’ access and standardised production. Here the authors have developed a multidimensional workflow profiling platform for EBV-specific T cell therapy and show that correlative biomarkers of T cell potency and effector function are associated with therapeutic effectiveness in xenogeneic mouse EBV-LCL models.

Corey Smith
Vijayendra Dasari
Rajiv Khanna
ResearchOpen Access07 Jan 2026
Nature Communications

Volume: 17, P: 1-14
Making a droplet: the adipogenin–seipin complex at work

Adipogenin is a microprotein expressed in adipose tissue. Previous studies have suggested its role in lipid storage, yet the underlying molecular mechanisms have been unclear. A recent study published in Science presents evidence that adipogenin forms complexes with seipin, a protein that is essential for lipid droplet formation in adipocytes, thereby modulating lipid storage.

Daniel Tews
Pamela Fischer-Posovszky
News & Views10 Feb 2026
Nature Reviews Endocrinology

P: 1-2
Segmented filamentous bacteria undergo a structural transition at their adhesive tip during unicellular to filament development

Segmented Filamentous Bacteria (SFB) are understudied commensals that promote immune activation through their attachment to the intestinal epithelium. Here, Cruz et al. use cryo-electron microscopy and tomography to identify various surface structures and uncover a developmental transition at the SFB adhesive tip.

Ana Raquel Cruz
Benedikt H. Wimmer
Pamela Schnupf
ResearchOpen Access17 Dec 2025
Nature Communications

Volume: 17, P: 1-20
cellSTAAR: incorporating single-cell-sequencing-based functional data to boost power in rare variant association testing of noncoding regions

cellSTAAR advances noncoding rare variant association analysis by integrating single-cell genomics data.

Eric Van Buren
Yi Zhang
Xihong Lin
Research31 Dec 2025
Nature Methods

Volume: 23, P: 338-349
Recovery from the ‘Lethal’ Effects of Cross-Linking Alkylation

A. LOVELESS
JUDY COOK
PAMELA WHEATLEY
Research01 Mar 1965
Nature

Volume: 205, P: 980-983
GDF3 promotes adipose tissue macrophage-mediated inflammation via altered chromatin accessibility during aging

Jang and colleagues demonstrate that GDF3 reshapes the chromatin landscape of inflammatory adipose tissue macrophages and drives endotoxic inflammation with age. Pharmacological inhibition of the GDF3–SMAD2/3 axis alleviates endotoxemia lethality in old mice.

In Hwa Jang
Anna Carey
Christina D. Camell
ResearchOpen Access15 Dec 2025
Nature Aging

Volume: 6, P: 127-142
A binary self-amplifying expression platform enabling lipid nanoparticle-free vaccines and nanomedicines

The authors present Gemini, their bifunctional replicon platform capable of functioning as either self-amplifying RNA (saRNA) or self-amplifying DNA (saDNA).

Wilfred A. Jefferies
Kyung Bok Choi
Cheryl G. Pfeifer
ResearchOpen Access22 Dec 2025
Nature Communications

Volume: 16, P: 1-21
Functional implications of polygenic risk for schizophrenia in human neurons

Here the authors perturb genes linked to schizophrenia risk in human neurons. They find that single perturbations share common downstream effects on gene networks, while joint perturbations result in downstream effects being saturated.

PJ Michael Deans
Kayla G. Retallick-Townsley
Kristen J. Brennand
ResearchOpen Access10 Jan 2026
Nature Communications

Volume: 17, P: 1-23
Haemoglobin A′₂ : α₂δ₂16 Glycine→Arginine

E. W. BALL
M. J. MEYNELL
A. O. W. STRETTON
Research19 Mar 1966
Nature

Volume: 209, P: 1217-1218
The Yard Unit of Length

P. H. BIGG
PAMELA ANDERTON
Research23 Nov 1963
Nature

Volume: 200, P: 730-732
Some New Vertebrate Fossils from the Panchet Series of West Bengal

PAMELA LAMPLUGH ROBINSON
Research20 Dec 1958
Nature

Volume: 182, P: 1722-1723
C-COMPASS: a user-friendly neural network tool profiles cell compartments at protein and lipid levels

C-COMPASS is an open-source software designed to predict the spatial cellular distribution of proteins and lipids from cellular organelle profiling using a neural network-based regression model.

Daniel T. Haas
Daniel Weindl
Natalie Krahmer
ResearchOpen Access04 Dec 2025
Nature Methods

Volume: 23, P: 118-130
In vivo gene editing of human hematopoietic stem and progenitor cells using envelope-engineered virus-like particles

Virus-like particles are engineered to edit human hematopoietic cells in vivo.

Vladimir V. Botchkarev Jr.
Sean Harrington
Luca Biasco
ResearchOpen Access05 Dec 2025
Nature Biotechnology

P: 1-13
Identification of Water-Masses by their Suspended Matter

W. R. G. ATKINS
PAMELA G. JENKINS
Research28 May 1955
Nature

Volume: 175, P: 951
Cleavage and nuclear localization of the rice XA21 immune receptor

The rice pattern recognition receptor—XA21—confers immunity against the Gram-negative bacterial pathogen,Xanthomonas oryzae pv. oryzae. This study shows that the intracellular kinase domain of XA21 translocates to the nucleus and that this translocation is essential for the XA21-mediated immune response.

Chang-Jin Park
Pamela C. Ronald
ResearchOpen Access26 Jun 2012
Nature Communications

Volume: 3, P: 1-6
A New Vertebrate Fauna from the Early Jurassic of the Deccan, India

SOHAN LALL JAIN
PAMELA LAMPLUGH ROBINSON
TAPAN K. ROY CHOWDHURY
Research26 May 1962
Nature

Volume: 194, P: 755-757
Assembly of the infant gut microbiome and resistome are linked to bacterial strains in mother’s milk

Here, with metagenomic analyses on longitudinal samples collected from 195 mother-infant pairs, the authors show that the breast milk microbiome contributes to infant gut assembly through bacterial strain sharing and antimicrobial resistance gene overlap during the first six months of life.

Pamela Ferretti
Mattea Allert
Ran Blekhman
ResearchOpen Access22 Nov 2025
Nature Communications

Volume: 16, P: 1-15
Satellite Observations of Solar Cosmic Rays

PAMELA ROTHWELL
CARL McILWAIN
Research18 Jul 1959
Nature

Volume: 184, P: 138-140
Mapping the genetic landscape across 14 psychiatric disorders

Genomic analyses applied to 14 childhood- and adult-onset psychiatric disorders identifies five underlying genomic factors that explain the majority of the genetic variance of the individual disorders.

Andrew D. Grotzinger
Josefin Werme
Jordan W. Smoller
ResearchOpen Access10 Dec 2025
Nature

Volume: 649, P: 406-415
Structural mechanism of anti-MHC-I antibody blocking of inhibitory NK cell receptors in tumor immunity

The B1.23.2 antibody binds HLA-B*44:05 at a site that overlaps the killer Ig-like receptor binding site. It blocks inhibitory receptor interactions, leads to NK cell activation and suppresses tumor growth in a humanized mouse model.

Jiansheng Jiang
Abir K. Panda
David H. Margulies
ResearchOpen Access02 Feb 2026
Communications Biology

P: 1-16
Natural strategies for the spatial optimization of metabolism in synthetic biology

Christina M Agapakis
Patrick M Boyle
Pamela A Silver
Reviews17 May 2012
Nature Chemical Biology

Volume: 8, P: 527-535
Ligand induced cleavage and nuclear localization of the rice XA21 immune receptor

Chang-Jin Park
Pamela Ronald
ResearchOpen Access23 Jan 2012
Nature Precedings

P: 1
Towards fair decentralized benchmarking of healthcare AI algorithms with the Federated Tumor Segmentation (FeTS) challenge

Federated learning (FL) algorithms have emerged as a promising solution to train models for healthcare imaging across institutions while preserving privacy. Here, the authors describe the Federated Tumor Segmentation (FeTS) challenge for the decentralised benchmarking of FL algorithms and evaluation of Healthcare AI algorithm generalizability in real-world cancer imaging datasets.

Maximilian Zenk
Ujjwal Baid
Spyridon Bakas
ResearchOpen Access08 Jul 2025
Nature Communications

Volume: 16, P: 1-20
Ubiquinone and Ubichromenol

J. STEVENSON
PAMELA J. HAYWARD
R. A. MORTON
Research29 Dec 1962
Nature

Volume: 196, P: 1291-1293
Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β-globin gene cluster

Stuart H. Orkin
Haig H. Kazazian Jr
Patricia J. V. Giardina
Research15 Apr 1982
Nature

Volume: 296, P: 627-631
A microenvironment-driven HLA-II-associated insulin neoantigen elicits persistent memory T cell activation in diabetes

The authors identify a Cys→Ser transformation (C19S) in insulin leading to neoepitope presentation and CD4⁺ T cell autoreactivity in type 1 diabetes. Inflammation and oxidative stress enhanced C19S transformation in β cells and antigen-presenting cells, resulting in C19S-specific CD4⁺ T cells with an activated memory phenotype linked to disease progression.

Neetu Srivastava
Anthony N. Vomund
Xiaoxiao Wan
ResearchOpen Access28 Nov 2025
Nature Immunology

Volume: 27, P: 82-97
Endotyping-informed therapy for patients with chest pain and no obstructive coronary artery disease: a randomized trial

As presented at the American Heart Association Conference 2025, patients with chest pain and without obstructive coronary artery disease benefit from treatment informed by cardiovascular magnetic resonance.

Conor P. Bradley
Gemma McKinley
Colin Berry
ResearchOpen Access10 Nov 2025
Nature Medicine

Volume: 32, P: 332-341
Deep-sea gas hydrate mounds and chemosynthetic fauna discovered at 3640 m on the Molloy Ridge, Greenland Sea

This study reveals dissociating methane hydrate mounds on the seafloor at more than 3600 m deep in the Greenland Sea. This gas hydrate cold seep supports chemosynthetic fauna similar to Arctic hydrothermal vents at similar depth, consistent with an overlap between vent and seep fauna in the region.

Giuliana Panieri
Jonathan T. Copley
Alex D. Rogers
ResearchOpen Access17 Dec 2025
Nature Communications

Volume: 16, P: 1-13
Geometry-induced spin chirality in a non-chiral ferromagnet at zero field

Three-dimensional chiral magnetic tubes created via two-photon lithography and nickel film deposition exhibit chiral spin textures and non-reciprocal magnon transport.

Mingran Xu
Axel J. M. Deenen
Dirk Grundler
ResearchOpen Access04 Dec 2025
Nature Nanotechnology

Volume: 21, P: 58-64
A missense mutation in the dystrophin gene in a Duchenne muscular dystrophy patient

Thomas W. Prior
Audrey C. Papp
Jerry R. Mendell
Research01 Aug 1993
Nature Genetics

Volume: 4, P: 357-360
Localization of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia

Nora Heisterkamp
John R. Stephenson
Gerard Grosveld
Research17 Nov 1983
Nature

Volume: 306, P: 239-242
Ferryl intermediates of catalase captured by time-resolved Weissenberg crystallography and UV-VIS spectroscopy

Patrice Gouet
Hélène-Marie Jouve
Janos Hajdu
Research01 Nov 1996
Nature Structural Biology

Volume: 3, P: 951-956
Thrombospondin-1–CD47 signaling contributes to the development of T cell exhaustion in cancer

Merghoub, Wolchok and colleagues reveal a role of the extracellular matrix protein thrombospondin-1 (TSP-1) and CD47 in promoting T cell exhaustion during tumor progression in mice and humans.

Chien-Huan Weng
Anais Assouvie
Taha Merghoub
Research17 Nov 2025
Nature Immunology

Volume: 26, P: 2296-2311
Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer

Pamela S. Ohashi
Tak W. Mak
Arthur Weiss
Research01 Aug 1985
Nature

Volume: 316, P: 606-609
Profiling of HIV-1 elite neutralizer cohort reveals a CD4bs bnAb for HIV-1 prevention and therapy

Klein and colleagues characterize 04_A06, a new V_H1-2-encoded broadly neutralizing antibody that has marked breadth and potency against extended multiclade HIV-1 pseudovirus panels and can maintain full viral suppression in HIV-1-infected humanized mice.

Lutz Gieselmann
Andrew T. DeLaitsch
Florian Klein
ResearchOpen Access06 Oct 2025
Nature Immunology

Volume: 26, P: 2016-2029
Arsenic enrichment patterns are defined by microbialite morphology, fabric, and accretion mechanism

Arsenic-rich globules are thought to be evidence of early microbial life. Here, the authors show how microbialite arsenic enrichment patterns vary with microbial activity and environmental conditions, reinforcing arsenic’s value as a biosignature.

Clément G. L. Pollier
R. Pamela Reid
Amanda M. Oehlert
ResearchOpen Access20 Nov 2025
Nature Communications

Volume: 16, P: 1-16
CSF total tau as a proxy of synaptic degeneration

CSF total tau (t-tau), often used as a marker of neuronal damage, is more strongly linked to synaptic degeneration. Here, the authors show that t-tau better reflects synaptic dysfunction than axonal or neuronal loss in Alzheimer’s disease.

Carolina Soares
Bruna Bellaver
Tharick A. Pascoal
ResearchOpen Access29 Aug 2025
Nature Communications

Volume: 16, P: 1-10
Satellite megaconstellations will threaten space-based astronomy

Rapidly growing satellite constellations pose a substantial threat to astronomical observations, with projections indicating that future space telescopes will have more than 96% of their exposures affected by satellite trails, necessitating urgent mitigation strategies.

Alejandro S. Borlaff
Pamela M. Marcum
Steve B. Howell
ResearchOpen Access03 Dec 2025
Nature

Volume: 648, P: 51-57
Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database

Here the authors provide an explanation for 95% of examined predicted loss of function variants found in disease-associated haploinsufficient genes in the Genome Aggregation Database (gnomAD), underscoring the power of the presented analysis to minimize false assignments of disease risk.

Sanna Gudmundsson
Moriel Singer-Berk
Anne O’Donnell-Luria
ResearchOpen Access31 Oct 2025
Nature Communications

Volume: 16, P: 1-14

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