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Atomically dispersed catalysts show promising activity for electrochemical reactions but often suffer from limited stability. Here, the authors report an atom-ordering strategy that forms triangular Co sites to activate the substrate for durable alkaline hydrogen production.

Thermal stability remains a key challenge for organic photovoltaics. Qin et al. now propose a strategy that stabilizes multiple components of the devices, enhancing their resilience under damp heat and thermal cycling conditions.

Thermal lepton pairs are ideal probes for the temperature of quark-gluon plasma. Here, the STAR Collaboration uses thermal electron-positron pair production to measure quark-gluon plasma average temperature at different stages of the evolution.

Adaptable control is essential for metasurfaces. Xingqi Xuan and colleagues propose a cyber-managed system with energy harvesting modules, offering a flexible solution for closed loop electromagnetic field manipulation and sensing.

A key feature of Majorana zero modes (MZMs) is their non-Abelian fusion rule, characterized by multiple outcomes. Here, the authors introduce a minimal setup where coupling a tunable fermionic mode to a single MZM allows the control of fusion loops, yielding distinct charge pumping that serves as a direct experimental signature.

A device for rectifying supercurrents at liquid-nitrogen temperature with high efficiency is demonstrated. This is a practical step towards implementing dissipationless electronics.

Finite momentum superconducting pairing refers to a class of unconventional superconducting states where Cooper pairs acquire a non-zero momentum. Here the authors report a new superconducting state in bulk 4Hb-TaS₂, where magnetic fields induce finite momentum pairing via magnetoelectric coupling.

This study demonstrates that resting-state fMRI networks can rapidly reconfigure in response to a single, 10-ms thalamic neural population activity input, revealing how brain networks mediate fast neural information flow and processing.

The development of fast-charging and high-capacity negative electrodes is critical for advanced lithium-ion batteries. Here, authors use a vacancy engineering strategy to develop a layered Prussian blue analogue with competitive rate capability, delivering a specific capacity of 510 mAh g⁻¹ at a specific current of 8 A g⁻¹.

Engineered polar nanoclusters in tin-doped barium titanate thin films enable microwave tunability of ~74% at 6 GHz under low bias, offering a strategy to achieve high tunability with minimal dielectric loss for microwave communication.

In ABA trilayer graphene, a temperature gradient generates a transverse voltage that scales quadratically with the gradient and reaches an effective Nernst coefficient of 300 µV K⁻¹ near the charge neutrality point.

Therapeutic gene editing in vivo is an ongoing challenge. Here, authors demonstrate Cas9 nickase guided DNA ligation as a nonviral method for installing permanent genomic corrections with favorable on target edit profiles in model animal cell types and adult mice.

In this study, the heterodimeric GABA_B receptor, a class C G protein-coupled receptor for the neurotransmitter GABA, is found to be allosterically activated by mechanical forces in a GABA independent manner through a direct interaction with integrin.

The hydrovoltaic effect offers a promising route for ion sensing but is limited by a long response time. Here, the authors leverage rapid ion transport within nanochannels to achieve a high voltage output of 4.0 V with a response time of just 0.17 s.

Investigating the inner structure of baryons is important to further our understanding of the strong interaction. Here, the BESIII Collaboration extracts the absolute value of the ratio of the electric to magnetic form factors and its relative phase for e + e − → J/ψ → ΛΣ decays, enhancing the signal thanks to the vacuum polarisation effect at the J/ψ peak.

Nickelate superconductors attract enormous attention in the field of high-temperature superconductivity. Here the authors report observation of perfect diamagnetism and interfacial effect on the electronic structures in infinite layer Nd_0.8Sr_0.2NiO₂ superconductors.

Through the sonochemical exfoliation of grown black phosphorus crystals, high-quality, narrow and clean black phosphorus nanoribbons with smooth edges and defined edge chirality are achieved, enabling the realization of high-performance transistors and photodetectors.

The understanding of the reemergence of pressure induced superconductivity in alkali-metal intercalated FeSe is hampered by sample complexities. Here, Sun et al. report the electronic properties of (Li_1–xFe _x )OHFe_1–ySe single crystal not only in the reemerged superconducting state but also in the normal state.

Phase transitions in topologically non-trivial systems are characterized by changes of topological invariants, rather than conventional order parameters. Here, the authors propose a real-space topological phase transition upon pair annihilation of emergent monopoles inherent in chiral magnet MnGe.

Cancer cells exploit altered metabolic pathways to dynamically regulate epigenetic methylations. Here, the authors show the canonical metabolic and nonmetabolic functions of PRPS2 in enhancing ATP utilization and SAM biosynthesis, promoting RNA m⁶A methylation for lung tumorigenesis and metastasis.

In returning Thouless pumping, the quantized charge is pumped during the first half of the cycle and returns to zero during the second. Here, authors demonstrate returning Thouless pumping experimentally with a symmetry-protected delicate topological insulator, made of a two-dimensional acoustic crystal.

Integrative analyses of transcriptome and whole-genome sequencing data for 1,188 tumours across 27 types of cancer are used to provide a comprehensive catalogue of RNA-level alterations in cancer.

The authors propose a graded ball milling strategy to improve the strength and efficiency of brittle Zintl thermoelectrics, enabling robust, high-performance modules for stable and scalable waste heat energy harvesting.

The quark structure of the f₀(980) hadron is still unknown after 50 years of its discovery. Here, the CMS Collaboration reports a measurement of the elliptic flow of the f₀(980) state in proton-lead collisions at a nucleon-nucleon centre-of-mass energy of 8.16 TeV, providing strong evidence that the state is an ordinary meson.

Data obtained from the MicroBooNE liquid-argon time projection chamber are used to exclude the single light sterile neutrino interpretation of the LSND and MiniBooNE anomalies at the 95% confidence level.

Immune interactions are complex, dynamic and difficult to capture using static imaging modalities on in vitro or ex vivo tissue cultures. In this Review, the authors discuss techniques for in vivo imaging of the immune system including one-photon near-infrared II fluorescence and two-photon and multiphoton microscopy for longitudinal tracking of immune cells, as well as a translational path that integrates near-infrared II, positron-emission tomography or MRI and artificial intelligence-enabled analysis towards quantitative, clinically compatible, multimodal immuno-imaging.

Analyses of 2,658 whole genomes across 38 types of cancer identify the contribution of non-coding point mutations and structural variants to driving cancer.

Entanglement was observed in top–antitop quark events by the ATLAS experiment produced at the Large Hadron Collider at CERN using a proton–proton collision dataset with a centre-of-mass energy of √s  = 13 TeV and an integrated luminosity of 140 fb⁻¹.

Experiments under upper-tropospheric conditions map the chemical formation of isoprene oxygenated organic molecules (important molecules for new particle formation) and reveal that relative radical ratios control their composition

An EC-NBI-based CAD system with advanced multi-stage pre-training fills endoscopy’s real-time diagnosis gap for colorectal lesions. It was shown to outperform other supervised methods and guides real-time biopsies.

The authors present SVclone, a computational method for inferring the cancer cell fraction of structural variants from whole-genome sequencing data.

Delocalized radical systems are appealing for controlling stereoselectivity in organic synthesis. Here the authors report on a Co(II)-based enantioselective radical system for the dearomative 1,7-conjugate amination of readily available 4-vinylphenols with aryl azides.

The synthesis of atom-thin amorphous films remains challenging as their thermodynamically favourable grains are neither two dimensional nor layered. Here a droplet-driven nanoribbon-to-film growth strategy is reported to achieve amorphous metal chalcogenides at the single-layer limit.

Electrocatalysts for CO₂ reduction are typically prepared and optimized ex situ before the reaction begins, but during reactions they may undergo changes that lower their performance. Here the authors show that active Cu catalysts can be formed on a recoverable basis and removed in situ during the CO₂ reduction reaction, improving the stability of the system.

It is extremely difficult to separate tritium from radioactively contaminated water. Here the authors introduce catalytic hydrogen isotope exchange to water distillation, realizing excellent detritiation performance.

Fractional quantum Hall states in 2D electron gases arise due to strong electron-electron interactions, which makes a general theoretical understanding difficult. Fu et al. present data showing the ν = 5/3 quantum Hall state has a 3/2 plateau in the diagonal resistance that has not been captured by existing models.

Absorption in one-port passive systems is known to be bound by causality constraints. Here, authors study reflection and transmission of a two-port system to introduce a generalized causality constraint based on duality symmetry. Experimentally, the broadened bandwidth of their meta-absorbers shows the untapped absorption potential of broadband acoustic metamaterials.

The authors identify feeblin, an inhibitory compound of the proinflammatory TLR7/8/9-IRF5 pathway with therapeutic potential, which acts by binding SLC15A4 via an allosteric mechanism mediating degradation of its signaling partner TASL.

Human primary monocytes reversibly phase separate into regular, multicellular, multilayered domains on soft matrices with physiological stiffness due to local activation and global inhibition processes that occur during random cell migration.

Zinc-ion batteries face challenges like dendrite formation, limiting their performance. Here, authors reveal that high-current deposition forms (002) textured Zn, enhancing cycling life, and propose guidelines for optimizing battery cycling protocols based on advanced in situ XRD analysis.

The realization of high-performance flexible perovskite/crystalline-silicon tandem solar cells requires efficient photocarrier transport and mitigation of residual stress. Here, authors reveal the critical role of perovskite phase homogeneity, achieving flexible devices with efficiency of 29.88%.

The properties of many high-temperature superconductors are governed by holes rather than electrons. Gauquelin et al. use atomic resolution electron energy loss spectroscopy to study the effect of oxygen doping on the valence of Cu ions and local electronic structure around the oxygen atoms in YBa₂Cu₃O_6+δ.

Authors use a high-entropy engineering approach to produce fully amorphous BiTO films by exfoliation and annealing, creating crystalline regions, leading to flexible ceramics with dielectric properties.

Analysis of cancer genome sequencing data has enabled the discovery of driver mutations. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium the authors present DriverPower, a software package that identifies coding and non-coding driver mutations within cancer whole genomes via consideration of mutational burden and functional impact evidence.

Observations of γ-rays with energies up to 1.4 PeV find that 12 sources in the Galaxy are PeVatrons, one of which is the Crab Nebula.

Parity-time symmetry breaking and related non-Hermitian phenomena, such as high-order exceptional points, have attracted significant interest across various experimental platforms. Here the authors demonstrate a third-order exceptional point induced by parity-time symmetry breaking in a dissipative trapped ion.

Ancient genomes from Neolithic rice-farming populations at Baligang reveal a demographic shift around 4,200 years ago and a 5,000-year-old patrilineal social structure, providing insights into the population history of East Asia.

Alternating copolymerization of cyclic anhydrides and epoxides is an interesting platform for the synthesis of polyesters from renewable resources, but the near irreversibility of the copolymerization makes it challenging to develop chemically recyclable polyesters with easy-to-tune structure. Here, the authors develop a recyclable polyester library from alternating copolymerization of aldehyde and cyclic anhydride.