Nature Search

Decoding cell state transitions driven by dynamic cell–cell communication in spatial transcriptomics

This Article introduces CCCvelo, a computational tool that uses spatial omics data to identify how cell–cell communication directs cell fate decisions, uncovering the spatiotemporal signaling dynamics that orchestrate development and diseases.

Lulu Yan
Dongyan Zhang
Xiaoqiang Sun
Research05 Jan 2026
Nature Computational Science

P: 1-15
Study on the transverse hardness distribution in strip-induced vibration of the Stand S4 cold rolling mill

Weiquan Sun
Xiaoqiang Yan
Weijing Yun
ResearchOpen Access04 Dec 2025
Scientific Reports

Volume: 16, P: 1-11
Author Correction: Cancer biomarkers discovered using pan-cancer plasma proteomic profiling

Lin Bai
Jiacheng Lyu
Chen Ding
Amendments and Corrections22 Sept 2025
Nature Biomedical Engineering

Volume: 10, P: 192
AI-based diagnosis of acute aortic syndrome from noncontrast CT

Going from model development to a pilot implementation study, a deep learning model shows that acute aortic syndrome can be diagnosed directly from noncontrast CT, increasing accuracy and decreasing time to diagnosis.

Yujian Hu
Yilang Xiang
Hongkun Zhang
ResearchOpen Access20 Aug 2025
Nature Medicine

Volume: 31, P: 3832-3844
Cancer biomarkers discovered using pan-cancer plasma proteomic profiling

Proteome profiling of plasma samples in human pan-cancer cohorts reveals patterns of biomarkers for diagnosis.

Lin Bai
Jiacheng Lyu
Chen Ding
Research02 Jul 2025
Nature Biomedical Engineering

Volume: 10, P: 16-38
LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc

lncRNA and cellular metabolism are frequently dysregulated in cancer. In this study, the authors discover the lncGLCC1 is increased in colorectal cancer cells under glucose starvation conditions and correlates with poor prognosis in this cancer.

Jiayin Tang
Tingting Yan
Jing-Yuan Fang
ResearchOpen Access02 Aug 2019
Nature Communications

Volume: 10, P: 1-15
Electricity-driven enzymatic dynamic kinetic oxidation

Reshaping of thiamine-dependent enzymes with ferrocene-mediated electrocatalysis can unlock an unnatural dynamic kinetic oxidation of α-branched aldehydes, providing new opportunities for making molecules.

Beibei Zhao
Yuanyuan Xu
Xiaoqiang Huang
Research28 May 2025
Nature

Volume: 643, P: 699-704
Experimental study on creep mechanical properties and failure modes of anthracite in dry and saturated states

Xiaoqiang Zhang
Jianbing Yan
Wenwei Wang
ResearchOpen Access27 Oct 2025
Scientific Reports

Volume: 15, P: 1-21
Spatial engineering of single-atom Fe adjacent to Cu-assisted nanozymes for biomimetic O₂ activation

Integrating heterogeneous single atom nanozyme (SAzyme) configurations and homogeneous enzyme-like mechanism is promising for optimizing SAzymes but elusive. Here the authors address this issue by developing a spatial engineering strategy to fabricate dual-sites SAzymes incorporating single atom Fe active centers (Fe–N₄) and Cu atomic sites (Cu–N₄) in a vertically stacked Fe–N₄ and Cu–N₄ geometry.

Ying Wang
Vinod K. Paidi
Kwok-Yin Wong
ResearchOpen Access12 Mar 2024
Nature Communications

Volume: 15, P: 1-13
Extraction process and antioxidant and antimicrobial activities of total flavonoids from Broussonetia papyrifera leaves

Xiaoqiang Huang
An Jia
Chunsheng Yan
ResearchOpen Access02 Dec 2025
Scientific Reports

Volume: 16, P: 1-13
Silicon heterojunction back-contact solar cells by laser patterning

We fabricated silicon heterojunction back-contact solar cells using laser patterning, producing cells that exceeded 27% power-conversion efficiency.

Hua Wu
Feng Ye
Xixiang Xu
Research01 Oct 2024
Nature

Volume: 635, P: 604-609
A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models

An AI-generated small-molecule inhibitor treats fibrosis in vivo and in phase I clinical trials.

Feng Ren
Alex Aliper
Alex Zhavoronkov
ResearchOpen Access08 Mar 2024
Nature Biotechnology

Volume: 43, P: 63-75
Manipulation of nonlinear optical responses in layered ferroelectric niobium oxide dihalides

This paper reports the intralayer ferroelectric-to-antiferroelectric and ferroelectric-toparaelectric phase transitions in layered NbOCl₂ and NbOI₂ under a small pressure, respectively, along with the strong manipulations of nonlinear optics.

Liangting Ye
Wenju Zhou
Bing Huang
ResearchOpen Access22 Sept 2023
Nature Communications

Volume: 14, P: 1-10
Pangenome analysis reveals genomic variations associated with domestication traits in broomcorn millet

Population analysis of 516 wild and domesticated broomcorn millet genomes and a graph-based pangenome based on de novo assemblies of 32 representative accessions identify genomic variations associated with domestication traits.

Jinfeng Chen
Yang Liu
Xianmin Diao
ResearchOpen Access30 Nov 2023
Nature Genetics

Volume: 55, P: 2243-2254
Microbiome and metabolome features in inflammatory bowel disease via multi-omics integration analyses across cohorts

Gut microbiota play pivotal roles in IBD. Here, Ning et al. use a multi-omics approach to characterize gut microbiota and metabolites alterations, and potential pathogenic bacteria associated with IBD, with the aim to help develop more precise biomarkers for IBD diagnosis and drug targets

Lijun Ning
Yi-Lu Zhou
Jie Hong
ResearchOpen Access06 Nov 2023
Nature Communications

Volume: 14, P: 1-17
The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment

The gut and oral microbiomes are altered in individuals with rheumatoid arthritis, and these changes can be used to stratify individuals for diagnostic and prognostic purposes.

Xuan Zhang
Dongya Zhang
Jun Wang
Research27 Jul 2015
Nature Medicine

Volume: 21, P: 895-905
Critical role of hydrogen for superconductivity in nickelates

In optimally doped Nd_0.8Sr_0.2NiO₂H epitaxial film, combined state-of-the-art experimental and theoretical approaches show abundant hydrogen with zero resistivity, and its critical role in superconductivity in epitaxial infinite-layer nickelates.

Xiang Ding
Charles C. Tam
Liang Qiao
Research01 Mar 2023
Nature

Volume: 615, P: 50-55
A reduced lymphocyte ratio as an early marker for predicting acute pancreatitis

Xiuzhong Qi
Fangyong Yang
Lina Wang
ResearchOpen Access07 Mar 2017
Scientific Reports

Volume: 7, P: 1-7
Dynamic mode coupling in terahertz metamaterials

Xiaoqiang Su
Chunmei Ouyang
Weili Zhang
ResearchOpen Access02 Jun 2015
Scientific Reports

Volume: 5, P: 1-10
Comparison of microstructural evolution differences during dry-jet wet spinning and wet spinning for polyacrylonitrile precursor fiber

Jiping Wang
Xiaoqiang Ji
Weisong Zhang
ResearchOpen Access25 Jul 2025
Scientific Reports

Volume: 15, P: 1-13
Investigating the effect of Arvcf reveals an essential role on regulating the mesolimbic dopamine signaling-mediated nicotine reward

Catenin gene Arvcf promotes theformation of nicotine reward learning behavior by enhancing the mesolimbic dopamine signaling in mice.

Yan Wang
Zhongli Yang
Ming D. Li
ResearchOpen Access13 Mar 2025
Communications Biology

Volume: 8, P: 1-14
Using tide for rainfall runoff simulation with feature projection and reversible instance normalization

Zheng Fang
Simin Qu
Yu Yu
ResearchOpen Access28 Feb 2025
Scientific Reports

Volume: 15, P: 1-15
Study on the regulation of gastric cancer cell apoptosis by LACTB through mitochondrial autophagy pathway

Wei Nie
Lihua Hu
Fang Yang
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-13
Integrative analysis of genetics, epigenetics and RNA expression data reveal three susceptibility loci for smoking behavior in Chinese Han population

Ming D. Li
Qiang Liu
Zhongli Yang
Research24 May 2024
Molecular Psychiatry

Volume: 29, P: 3516-3526
Failure patterns and individualized treatment plans of reirradiation for inoperable locally recurrent nasopharyngeal carcinoma

Cheng Lin
Qiongjiao Lu
Jingfeng Zong
ResearchOpen Access02 Aug 2024
Scientific Reports

Volume: 14, P: 1-10
Interplay between the Westerlies and Asian monsoon recorded in Lake Qinghai sediments since 32 ka

Zhisheng An
Steven M. Colman
Xinwen Xu
ResearchOpen Access31 Aug 2012
Scientific Reports

Volume: 2, P: 1-7
miR-146a is essential for lipopolysaccharide (LPS)-induced cross-tolerance against kidney ischemia/reperfusion injury in mice

Yan Dai
Ping Jia
Xiaoqiang Ding
ResearchOpen Access02 Jun 2016
Scientific Reports

Volume: 6, P: 1-12
Advancing ischemic stroke diagnosis and clinical outcome prediction using improved ensemble techniques in DSC-PWI radiomics

Mazen M. Yassin
Jiaxi Lu
Yan Kang
ResearchOpen Access11 Nov 2024
Scientific Reports

Volume: 14, P: 1-17
Acoustic recordings provide detailed information regarding the behavior of cryptic wildlife to support conservation translocations

Xiao Yan
Hemin Zhang
Yan Huang
ResearchOpen Access26 Mar 2019
Scientific Reports

Volume: 9, P: 1-11
Risk SNP-induced lncRNA-SLCC1 drives colorectal cancer through activating glycolysis signaling

Tingting Yan
Chaoqin Shen
Jing-Yuan Fang
ResearchOpen Access19 Feb 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-13
Variant of SNP rs1317082 at CCSlnc362 (RP11-362K14.5) creates a binding site for miR-4658 and diminishes the susceptibility to CRC

Chaoqin Shen
Tingting Yan
Jie Hong
ResearchOpen Access05 Dec 2018
Cell Death & Disease

Volume: 9, P: 1-11
LncRNA CACClnc promotes chemoresistance of colorectal cancer by modulating alternative splicing of RAD51

Xinyu Zhang
Dan Ma
Jie Hong
Research11 Mar 2023
Oncogene

Volume: 42, P: 1374-1391
Association between Insomnia and Metabolic Syndrome in a Chinese Han Population: A Cross-sectional Study

Yan Wang
Tian Jiang
Junzheng Chen
ResearchOpen Access07 Sept 2017
Scientific Reports

Volume: 7, P: 1-8
A high-quality chromosome-scale genome assembly of Xingan mandarin (Citrus reticulata ‘Xingan’), a primitive Mandarin type

Chongling Deng
Xiaoxiao Wu
Xiaoqiang Guo
ResearchOpen Access17 Jul 2025
Scientific Data

Volume: 12, P: 1-10
Correction: Corrigendum: A reduced lymphocyte ratio as an early marker for predicting acute pancreatitis

Xiuzhong Qi
Fangyong Yang
Lina Wang
Amendments and CorrectionsOpen Access07 Jun 2017
Scientific Reports

Volume: 7, P: 1
METTL14 aggravates podocyte injury and glomerulopathy progression through N⁶-methyladenosine-dependent downregulating of Sirt1

Zhihui Lu
Hong Liu
Xiaoqiang Ding
ResearchOpen Access27 Sept 2021
Cell Death & Disease

Volume: 12, P: 1-15
A 16q22.1 variant confers susceptibility to colorectal cancer as a distal regulator of ZFP90

Chen-Yang Yu
Ji-Xuan Han
Jing-Yuan Fang
ResearchOpen Access22 Oct 2019
Oncogene

Volume: 39, P: 1347-1360
CBX8 exhibits oncogenic properties and serves as a prognostic factor in hepatocellular carcinoma

Bo Tang
Yu Tian
Songqing He
ResearchOpen Access18 Jan 2019
Cell Death & Disease

Volume: 10, P: 1-14
Fused Deposition Modeling (FDM) 3D Printed Tablets for Intragastric Floating Delivery of Domperidone

Xuyu Chai
Hongyu Chai
Xiaoqiang Xiang
ResearchOpen Access06 Jun 2017
Scientific Reports

Volume: 7, P: 1-9
Safety and superior immunogenicity of heterologous boosting with an RBD-based SARS-CoV-2 mRNA vaccine in Chinese adults

Xiaoqiang Liu
Yuhua Li
Cheng-Feng Qin
CorrespondenceOpen Access14 Jun 2022
Cell Research

Volume: 32, P: 777-780
Overexpression of SerpinE2/protease nexin-1 Contribute to Pathological Cardiac Fibrosis via increasing Collagen Deposition

Xuelian Li
Dandan Zhao
Hongli Shan
ResearchOpen Access23 Nov 2016
Scientific Reports

Volume: 6, P: 1-12

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