Nature Search

Comparison of Reduced Alkylated Derivatives of some Myeloma Globulins and Bence-Jones Proteins

M. D. POULIK
G. M. EDELMAN
Research23 Sept 1961
Nature

Volume: 191, P: 1274-1276
Interchain Disulphide Bridge in Bence–Jones Proteins and in γ-Globulin B Chains

C. MILSTEIN
Research01 Mar 1965
Nature

Volume: 205, P: 1171-1173
Variations in Amino-Acid Sequence Near the Disulphide Bridges of Bence-Jones Proteins

C. MILSTEIN
Research22 Jan 1966
Nature

Volume: 209, P: 370-373
Natural variability of the climate system and detection of the greenhouse effect

T. M. L. Wigley
S. C. B. Raper
Research22 Mar 1990
Nature

Volume: 344, P: 324-327
Natural occurrence of 2-5A in interferon-treated EMC virus-infected L cells

B. R. G. Williams
R. R. Golgher
I. M. Kerr
Research06 Dec 1979
Nature

Volume: 282, P: 582-586
Nature of Haemoglobin M_Oldenburg

C. PIK
O. TÖNZ
Research11 Jun 1966
Nature

Volume: 210, P: 1182
Suppression of PCBM dimer formation in inverted perovskite solar cells

The authors develop a molecular dopant to avoid the dimerization of the electron-selective material phenyl-C₆₁-butyric acid methyl ester, resulting in enhanced stability and efficiency in inverted perovskite solar cells.

Zheng Liang
Huifen Xu
Nam-Gyu Park
Research30 Sept 2025
Nature Materials

P: 1-8
Observation of full-parameter Jones matrix in bilayer metasurface

The realization of Jones matrix with full eight free parameters is particularly challenging. Here, the authors construct spatially varying Jones matrix with eight free parameters by cascading two-layer metasurfaces and use it for new optical functionalities.

Yanjun Bao
Fan Nan
Baojun Li
ResearchOpen Access07 Dec 2022
Nature Communications

Volume: 13, P: 1-8
Distribution of an Arginine–Lysine Interchange in the Invariable Half of Human L-Type Bence-Jones Proteins

R. QUATTROCCHI
D. CIOLI
C. BAGLIONI
Research07 Oct 1967
Nature

Volume: 216, P: 56-57
Molecular insights into how the motions of the β-barrel and POTRA domains of BamA are coupled for efficient function

BamA is the catalytic core of the BAM complex, which inserts proteins into bacterial outer membranes. Here, the authors show that hinge flexibility between BamA’s β-barrel and POTRA domains is vital, demonstrating how evolution has fine-tuned the BamA sequence and structure for function.

Naemi Csoma
Jonathan M. Machin
Jean-François Collet
ResearchOpen Access03 Oct 2025
Nature Communications

Volume: 16, P: 1-16
Fabrication of cytotoxic mirror image nanopores

Mirror image peptides are of interest for a range of biotechnology applications. Here, the authors report on the creation of fully functional mirror-image transmembrane pores made of D-amino acid peptides, which have potential in nanopore sensing technologies and cancer therapies.

Neilah Firzan CA
Kalyanashis Jana
Kozhinjampara R. Mahendran
ResearchOpen Access02 Oct 2025
Nature Communications

Volume: 16, P: 1-13
A histomorphological atlas of resected mesothelioma discovered by self-supervised learning from 3446 whole-slide images

Mesothelioma is a highly lethal cancer that remains challenging to diagnose. Here, the authors curate a histomorphological atlas of resected mesothelioma and map it using self-supervised AI endorsed by human pathological assessment, revealing patterns that generate highly interpretable predictions.

Farzaneh Seyedshahi
Kai Rakovic
John Le Quesne
ResearchOpen Access07 Oct 2025
Nature Communications

Volume: 16, P: 1-14
Quantitative and mechanistic insights into proton dynamics for fast energy storage

Contributions of vehicular and structural proton transport are quantified in phosphoric acid electrolytes, with linking structural diffusion to hydrogen bonds. The derived conductivity model guides electrolyte-conductivity trends and identifies 5.8 M for low-temperature batteries.

Ziyue Li
Yuxiao Lin
Fei Wang
Research03 Oct 2025
Nature Materials

P: 1-10
What is the genotype of X..us Jones, 1900, based upon a species erroneously determined as albus Smith, 1890?

C. W. STILES
Research20 Apr 1911
Nature

Volume: 86, P: 246
Nature of the Circulating Thyroid Hormone

J. C. LAIDLAW
Research26 Nov 1949
Nature

Volume: 164, P: 927-928
Amino-acid Composition of Bence–Jones Protein

S. C. PAPASTAMATIS
J. E. KENCH
JOHN F. WILKINSON
Research03 Dec 1949
Nature

Volume: 164, P: 961
Trans-eQTL mapping prioritises USP18 as a negative regulator of interferon response at a lupus risk locus

Here the authors perform a trans expression quantitative trait locus meta-analysis study of over 3,700 people and link a USP18 variant to expression of 50 inflammation genes and lupus risk, highlighting how genetic regulation of immune responses drives autoimmune disease and informs new therapies.

Krista Freimann
Anneke Brümmer
Kaur Alasoo
ResearchOpen Access02 Oct 2025
Nature Communications

Volume: 16, P: 1-15
Nature and site of phospholamban regulation of the Ca²⁺ pump of sarcoplasmic reticulum

P. James
M. Inui
E. Carafoli
Research02 Nov 1989
Nature

Volume: 342, P: 90-92
Directing selective solvent presentations at electrochemical interfaces to enable initially anode-free sodium metal batteries

Electrolyte design faces challenges of balancing stability at both electrodes. Here, authors present an electrolyte design strategy to direct distinct solvent molecules to negative and positive electrodes respectively, achieving good stability in initially anode-free sodium metal batteries.

Qianli Xing
Jung Min Lee
Fang Liu
ResearchOpen Access15 Sept 2025
Nature Communications

Volume: 16, P: 1-13
Neuron-reactive KIR⁺CD8⁺ T cells display an encephalitogenic transcriptional program in autoimmune encephalitis

Autoimmune encephalitis (AIE) may involve neuron-specific cytotoxic T cells, but evidence is still lacking. Here the authors use induced pluripotent stem cells from patients with AIE and single cell RNA-sequencing of ex vivo CD8 T cells to find neuron-specific, KIR⁺CD8⁺ T cells with altered transcriptome that potentially contribute to AIE etiology.

Sylvain Perriot
Samuel Jones
Renaud Du Pasquier
ResearchOpen Access29 Sept 2025
Nature Communications

Volume: 16, P: 1-16
Nature of Acquired Resistance to Filarial Infection in Albino Rats

R. C. BAGAI
D. SUBRAHMANYAM
Research14 Nov 1970
Nature

Volume: 228, P: 682-683
Poziotinib for EGFR exon 20-insertion NSCLC: Clinical efficacy of the phase 2 ZENITH trial and differential impact of EGFR exon 20 insertion location on sensitivity

The location of EGFR exon 20 loop insertions (EGFRex20ins) has been shown to alter sensitivity to lung cancer therapy. Here, the authors report the results of the ZENITH20 clinical trial investigating poziotinib (EGFR TKI) in lung cancer patients and, combining with a similar trial, investigate how structural differences due to location of EGGFRex20ins alters sensitivity to EGFR TKI.

Xiuning Le
Jacqulyne P. Robichaux
John V. Heymach
ResearchOpen Access24 Sept 2025
Nature Communications

Volume: 16, P: 1-14
Polygenic and developmental profiles of autism differ by age at diagnosis

A study of several longitudinal birth cohorts and cross-sectional cohorts finds only moderate overlap in genetic variants between autism that is diagnosed earlier and that diagnosed later, so they may represent aetiologically different conditions.

Xinhe Zhang
Jakob Grove
Varun Warrier
ResearchOpen Access01 Oct 2025
Nature

P: 1-12
Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site

Crystal structures of HIV Env trimer with native glycosylation in complex with neutralizing antibodies reveal a glycan shield of high-mannose and complex-type N-glycan and indicate a path for germline-targeting vaccine design.

Harry B Gristick
Lotta von Boehmer
Pamela J Bjorkman
Research12 Sept 2016
Nature Structural & Molecular Biology

Volume: 23, P: 906-915
Development of clinical immunity to Plasmodium vivax following repeat controlled human malaria infection

Understanding the mechanisms behind clinical immunity to malaria is crucial for developing effective interventions. Here, the authors demonstrate that clinical immunity to Plasmodium vivax develops rapidly after a single controlled human malaria infection, reducing inflammatory responses and protecting against symptoms, while not significantly affecting parasite load.

Mimi M. Hou
Adam C. Harding
Angela M. Minassian
ResearchOpen Access25 Sept 2025
Nature Communications

Volume: 16, P: 1-13
Aberrant intermediate alveolar epithelial cells promote pathogenic activation of lung fibroblasts in preclinical fibrosis models

The direct contribution of aberrant epithelial cells to lung fibrosis is largely unknown. The authors use murine and human systems to identify how these cells activate fibroblasts, and how reciprocal signals cause them to enter a profibrotic state.

Evan T. Hoffman
Anit Shah
Jeremy Katzen
ResearchOpen Access30 Sept 2025
Nature Communications

Volume: 16, P: 1-20
Naturally occurring antibodies devoid of light chains

C. Hamers-Casterman
T. Atarhouch
R. Hammers
Research03 Jun 1993
Nature

Volume: 363, P: 446-448
Tumour-specific STING agonist synthesis via a two-component prodrug system

STING is a promising drug target, but selective activation is necessary for safety and efficacy. Researchers have developed a two-component prodrug system for potent pharmacological activation of STING that offers excellent tumour targeting.

Nai-Shu Hsu
Cong Tang
Gonçalo J. L. Bernardes
ResearchOpen Access16 Sept 2025
Nature Chemistry

P: 1-11
Natural selection on body size and proportions in house sparrows

Robert C. Fleischer
Richard F. Johnston
Research19 Aug 1982
Nature

Volume: 298, P: 747-749
Nature of the Lepidopteron Sensing Mechanism: Possible Photochemical Response

W. C. LEVENGOOD
I. I. ELDUMIATI
R. FREELING
Research23 Feb 1973
Nature

Volume: 241, P: 545-547
National hydrologic connectivity classification links wetlands with stream water quality

A national classification system of wetland hydrologic connectivity to streams, which could be applied globally, demonstrates and advances current understanding of how wetland connectivity affects surface water quality.

Scott G. Leibowitz
Ryan A. Hill
Charles R. Lane
ResearchOpen Access06 Apr 2023
Nature Water

Volume: 1, P: 370-380
Nationwide geospatial analysis of county racial and ethnic composition and public drinking water arsenic and uranium

Environmental justice and drinking water in the US: Higher proportions of Hispanic/Latino, American Indian/Alaskan Native, and non-Hispanic Black residents were associated with higher public water arsenic and uranium at the county-level, findings differed by region.

Irene Martinez-Morata
Benjamin C. Bostick
Anne E. Nigra
ResearchOpen Access03 Dec 2022
Nature Communications

Volume: 13, P: 1-12
Invariance of dynamo action in an early-Earth model

Early-Earth geometry models are presented, producing magnetic field intensity and morphologies agreeing with palaeomagnetic data in the deep past and demonstrating the negligible role of fluid viscosity in the Earth’s early geodynamo.

Yufeng Lin
Philippe Marti
Andrew Jackson
Research30 Jul 2025
Nature

Volume: 644, P: 109-114
The dependence of urban tick and Lyme disease hazards on the hinterlands

Context counts, and not just for social and economic aspects of urban life. This study finds that, for 16 cities in the United Kingdom, the landcover of the rural surroundings is a better predictor of ticks and environmental Lyme disease hazard than the landcover within the cities themselves.

Sara L. Gandy
Jessica L. Hall
Lucy Gilbert
ResearchOpen Access23 Sept 2025
Nature Cities

P: 1-10
Redox-driven mineral and organic associations in Jezero Crater, Mars

A geological, petrographic and geochemical survey of distinctive mudstone and conglomerate outcrops of the Bright Angel formation on Mars reveals textures, chemical and mineral characteristics, and organic signatures that warrant consideration as potential biosignatures.

Joel A. Hurowitz
M. M. Tice
Z. U. Wolf
ResearchOpen Access10 Sept 2025
Nature

Volume: 645, P: 332-340
An alternative route for β-hydroxybutyrate metabolism supports cytosolic acetyl-CoA synthesis in cancer cells

Kaluba, Rogers et al. show that in cancer cells that can metabolize ketones, they may reroute them to produce cytosolic acetyl-CoA and support tumour growth.

Faith C. Kaluba
Thomas J. Rogers
Evan C. Lien
ResearchOpen Access08 Sept 2025
Nature Metabolism

P: 1-12
High-density soft bioelectronic fibres for multimodal sensing and stimulation

High-density multimodal soft bioelectronic fibres provide a platform for minimally invasive implantable electronics, where diverse sensing and stimulation functionalities can be effectively integrated.

Muhammad Khatib
Eric Tianjiao Zhao
Zhenan Bao
Research17 Sept 2025
Nature

Volume: 645, P: 656-664
A blueprint for biomolecular condensation driven by bacterial microcompartment encapsulation peptides

Bacteria are increasingly known to employ internal organization strategies. Here, authors demonstrate that bacterial encapsulation peptides cause self-condensation of associated protein domains. These peptides may allow for programmable spatial control of metabolism.

Daniel S. Trettel
Cesar A. López
Cesar Raul Gonzalez-Esquer
ResearchOpen Access11 Aug 2025
Nature Communications

Volume: 16, P: 1-15
Sir John Lennard-Jones, K.B.E., F.R.S.

C. A. COULSON
Comments & Opinion27 Nov 1954
Nature

Volume: 174, P: 994-995
Large-scale GWAS of strabismus identifies risk loci and provides support for a link with maternal smoking

This large meta-analysis of 11 GWAS identified 7 genetic loci associated with strabismus, esotropia and exotropia. Mendelian randomisation provided genetic evidence of the causal link between maternal smoking to increased strabismus risk in offspring.

Weixiong He
Peter J. van der Most
Stuart MacGregor
ResearchOpen Access23 Aug 2025
Nature Communications

Volume: 16, P: 1-14
Exploiting hidden singularity on the surface of the Poincaré sphere

Arising from singularity on the surface of Poincaré sphere, topology-protected phase for co-polarized light enables 2π phase modulation, which complements the classical cross-polarized Pancharatnam-Berry phase and expands the versatility of flat optics.

Jinxing Li
Aloke Jana
Patrice Genevet
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-7
Elliptic anisotropy measurement of the f₀(980) hadron in proton-lead collisions and evidence for its quark-antiquark composition

The quark structure of the f₀(980) hadron is still unknown after 50 years of its discovery. Here, the CMS Collaboration reports a measurement of the elliptic flow of the f₀(980) state in proton-lead collisions at a nucleon-nucleon centre-of-mass energy of 8.16 TeV, providing strong evidence that the state is an ordinary meson.

A. Hayrapetyan
A. Tumasyan
A. Zhokin
ResearchOpen Access27 Aug 2025
Nature Communications

Volume: 16, P: 1-19
Dr. U. S. Haslam-Jones

E. C. TITCHMARSH
Comments & Opinion03 Nov 1962
Nature

Volume: 196, P: 413-414
Reaching the efficiency limit of arbitrary polarization transformation with non-orthogonal metasurfaces

The authors showcase a general method to engineer arbitrary polarization transformation with efficiency reaching nearly unity, taking advantage of non-orthogonal eigen-formalism of Jones matrix to circumvent the limitation of conventional polarization optics.

Yueyi Yuan
Kuang Zhang
Patrice Genevet
ResearchOpen Access06 Aug 2024
Nature Communications

Volume: 15, P: 1-10
A Contractile Protein Model for Cell Adhesion

P. C. T. JONES
Research22 Oct 1966
Nature

Volume: 212, P: 365-369
DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution

Integrated multi-omic analyses using samples from the TRACERx study highlight cross-talk between DNA hypermethylation and genomic lesions in non-small cell lung cancer.

Francisco Gimeno-Valiente
Carla Castignani
Nnennaya Kanu
ResearchOpen Access10 Sept 2025
Nature Genetics

Volume: 57, P: 2226-2237
Mr. H. Chapman Jones

J. C. P.
Comments & Opinion16 Apr 1932
Nature

Volume: 129, P: 570
Prof. E. Taylor Jones

S. C. CURRAN
Comments & Opinion18 Nov 1961
Nature

Volume: 192, P: 605
A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas

A subset of pediatric gliomas harbour alterations in fibroblast growth factor receptor (FGFR)-family proteins. Here, the authors characterise the genomic landscape of 11,635 gliomas across ages and use isogenic model systems to explore the underlying biology of FGFR1-altered gliomas and potential therapeutic vulnerabilities.

April A. Apfelbaum
Eric Morin
Pratiti Bandopadhayay
ResearchOpen Access31 Jul 2025
Nature Communications

Volume: 16, P: 1-23
Professor O. T. Jones

C. J. STUBBLEFIELD
Comments & Opinion17 Jun 1967
Nature

Volume: 214, P: 1279

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