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A combination of Floquet engineering and higher-order topological insulators has been lately only theoretically proposed. Here the authors experimentally realize an acoustic waveguides array to demonstrate a Floquet higherorder topological insulator extending its band topology from first order to higher order.

Longitudinal calcium imaging reveals the ability of corner cells to synchronize their activity with the environment, with the results implying the potential of the subiculum to contain the information required to reconstruct spatial environments.

Near-field radiative heat transfer between two coplanar silicon carbide membranes in close proximity is enhanced by the electromagnetic corner and edge modes.

Cuprates exhibit exotic states because of the interplay between spin, charge and orbital degrees of freedom. Ab initio calculations now show that a mechanism called orbital expansion plays a key role in the magnetic properties of cuprates.

The realization of a two-dimensional quadrupole topological insulator—featuring gapless corner states but an otherwise insulating bulk and edge—establishes electrical circuits as a versatile platform for implementing topological band structures.

For weak M4 earthquakes, this study finds complex rupture propagations at scales as small as 100 m. The underlying heterogeneity of the earthquake source is constrained by both seismic data and dynamic rupture physics.

Most non-line-of-sight imaging requires scanned illumination, limiting applicability for dynamic scenes. Here the authors exploit occlusion and a sensor array to estimate locations and sizes of moving foreground objects and a static background map.

Dirac fermion optics leverages p-n junctions and Klein tunnelling barriers present in materials to implement complex optical functions and devices, including reflectors, collimators, and Dirac fermion microscopes. Here, the authors fabricate Dirac fermion corner reflectors using bottom-gate-defined barriers in hBN-encapsulated graphene, and demonstrate high-frequency operation.

Efficient oxygen evolution relies on the development of promising catalysts. Herein, the authors demonstrate that cobalt tetrahedra, stabilized over the surface of YBCo₄O₇ material, can catalyze oxygen evolution reaction efficiently.

Multislice electron ptychography reveals that gradient-distributed ions induce progressive lattice distortions from bulk to surface, driving monoclinic γ-WO3 electrochromic materials to transform into tetragonal and cubic phases and forming the gradient-distributed colour centers.

Short-circuiting during fast charging through lithium dendrite intrusion into electrolytes is a major challenge in solid-state batteries. Here, using thermally annealed 3-nm-thick Ag coatings, lithium penetration into brittle electrolyte Li_6.6La₃Zr_1.6Ta_0.4O₁₂ is inhibited at local current densities of 250 mA cm⁻² due to an increase in surface fracture toughness.

Cryo-electron microscopy structures of three large ornate natural bacterial RNA molecules reveal their quaternary structures and intra- and intermolecular interactions that stabilize them.

BioPathNet predicts drug–disease indications, synthetic lethality and lncRNA–mRNA interactions using a deep learning framework.

The nature of the pairing symmetry in superconducting single-layer FeSe has been the subject of intense debate. Here, the authors use scanning tunneling microscopy/spectroscopy to show the absence of topological edge/corner modes, providing evidence for sign-preserving s-wave pairing.

The method for separating Cl₂ based on the Bernoulli principle enables efficient electrochemical chlorine evolution under universal pH conditions in a three-phase system. This enables assembly of a membrane-free system that can resist the influence of pH changes in the electrolyte.

This report describes a nanobody targeting glycine receptor mGlyR that inhibits its ability to regulate G protein signaling and produces anti-depressant effects in mice providing an immunotherapy approach to potentially treat depression.

A protocol for cryogenic 3D correlative focused ion beam milling using an integrated fluorescence light microscope and montage cryo-ET for nonadherent and adherent mammalian cells, as well as primary Drosophila melanogaster neurons.

This study demonstrates a low-energy photon device based on the kagome metal RbV₃Sb₅. It demonstrates that Fermi surface reconstruction, driven by a phase transition, leads to the emergence of van Hove singularities near the Fermi level.

This study reports two efficient methods—cyclic reduction and transfer matrix—to compute topological surface states in photonic and acoustic systems, cutting memory and time use by up to 100-fold and enabling the faster design of advanced topological devices.

The study introduces radio interferometric multiplexed spectroscopy (RIMS), a method designed to efficiently monitor the radio emissions of massive samples of stars. Applying it to LOFAR data, the authors identify stellar bursts, offering clues to possible star–planet magnetic interactions.

A strategy compatible with a broad range of materials by precisely manipulating optofluidic interactions within a confined 3D space to control the assembly of colloidal microparticles/nanoparticles is demonstrated, enabling the precise manufacture of complex microstructures/nanostructures.

Previous quantum simulations of higher-order topological phases have utilized synthetic dimensions. Here the authors simulate high-order topological phases on lattices with spatial dimension up to four on a superconducting quantum computer using a mapping to a many-body Hamiltonian in a reduced dimension.

Psychedelics and their non-hallucinogenic analogues were compared, revealing that serotonin 2A receptor (5-HT_2AR)-mediated G_i signalling is essential for hallucinogenic effect, with the functional mechanisms underlying this providing insights for designing therapeutic drugs without hallucinogenic effects.

Concerns over health misinformation online are becoming increasingly important. Here the authors show that older adults are more likely than younger people to encounter low-credibility health information online. Although exposure is limited overall, it is highest among those who already believe inaccurate health claims.

ALMA has captured exquisitely detailed images of bowshock shells in the outflow of an outbursting protostar. These provide important insights into the variable nature of the ejections from protostars, which play a key role in star and planet formation.

3D-printed gel microcilia arrays printed by two-photon polymerization and composed of a soft acrylic acid-co-acrylamide hydrogel with a nanometre-scale network structure are shown to respond to low-voltage electrical stimuli within milliseconds, enabling dynamic individual control and non-reciprocal 3D motion.

Higher order topological insulators (HOTIs) can provide an extension of the bulk-boundary correspondence associated with topological insulators, with more exotic physics behind localization of excitations at their boundaries and corners. Here, the authors propose a method for creating a class of HOTIs with unconventional boundary truncations, where the emergence of localized boundary modes of topological origin is associated with fractional Wannier centers and occurs across much broader parameter space in comparison with usual HOTIs.

European regions with the highest life expectancy, located in central and northern Spain, northern Italy, and Switzerland, continue to push the boundaries of human longevity, suggesting that there is still room for further lifespan extension.

The efficient low-temperature combustion of stable alkanes remains a major challenge in catalysis. Now it has been shown that a Pt–Nb dual-atom catalyst enables propane combustion through a distinct stepwise-boosting, current-assisted atomic relay mechanism, yielding complete conversion below 200 °C and a high turnover frequency.

Mice expressing humanized mutant tau exhibit synaptic loss and behavioral abnormalities in the absence of abnormal tau conformers, suggesting that hyperphosphorylated tau can be pathological, at least in tauopathies caused by tau isoform imbalance.

The meningeal compartment communicates with the brain to modulate homeostatic functions. Here, the authors demonstrate that natural killer (NK) cells and innate lymphoid cells (ILC) 1 shape synaptic neuronal transmission and affect mouse behavior.

JWST’s COSMOS-Web survey is used to create an ultra-high-detail dark matter map, revealing hidden filaments, clusters and distant structures. By tracing features out to z = 2, this map shows how dark and luminous matter build the cosmic web across cosmic time.

Surgical tasks within tortuous and narrow lumens require interventional instruments with controllable mechanical adaptability. Here, the authors present the Helixoft microrobotic system, which enables continuous stiffness tuning and active steering of microcatheters with diameters down to 300 μm controlled by weak magnetic fields.

To what extent regeneration recapitulates embryonic development is a longstanding question. Here, they show that embryonic gene modules are re-used, rewired, and interconnected to specific injury-induced down-stream targets during regeneration.

This study finds that native tree extinctions and alien naturalizations are pushing forests towards fast-growing, resource-demanding species. This global shift could affect carbon storage and ecosystem stability, highlighting the need to protect slow-growing trees.

Controllable and scalable phase transition of transition metal chalcogenides is challenging. Using in situ microscopic analysis, a non-stoichiometric phase transition from PdTe₂ to PdTe is observed on the atomic scale, providing mechanistic insights into the scalable phase engineering of transition metal chalcogenide films and heterostructures.

Tropical cyclone rain rates rise by over 20% in the 60 hours before landfall, which is driven by land–sea thermal and friction contrasts, heightening coastal flood risk. In addition, this enhancement has implications for forecasting and preparedness.

Here, the authors report the experimental discovery of such a dimensional hierarchy of the topologically-protected 2D surface states, 1D hinge states and 0D corner states in a single 3D acoustic system by using higher-order topological sonic crystals.

High-resolution ALMA observations reveal a gravitationally bound septuple protostar system in NGC 6334IN, formed through disk fragmentation. This discovery sheds light on the formation of extreme high-order multiplicity in massive stellar clusters.

Losses, due to their non-Hermitian nature, are generally disregarded or even considered harmful when looking for non-trivial topological phases. Here, the authors experimentally demonstrate that higher-order topology can emerge as a result of introducing losses in an acoustic crystal.

Formamidinium lead iodide perovskite films exhibit picosecond-scale quantum transients (~2 ps), with their nanoscale superlattices defining energy levels that yield narrow emission lines and reveal the structure–emission relationship.

Si, Dong, Xing and colleagues present ReTagX, a bright and compact array tag that restores photobleached signals via reversible and fluorogenic labelling, enabling long-term and high-resolution imaging of protein dynamics in living cells.

The 4D Nucleome Project demonstrates the use of genomic assays and computational methods to measure genome folding and then predict genomic structure from DNA sequence, facilitating the discovery of potential effects of genetic variants, including variants associated with disease, on genome structure and function.

A flexible micro-electrocorticography brain–computer interface that integrates a 256 × 256 array of electrodes, signal processing, data telemetry and wireless powering on a single complementary metal–oxide–semiconductor substrate can provide stable, chronic in vivo recordings.

Brain debris in mouse models of stroke is cleared by ultrasound, boosting recovery.