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Showing 1–50 of 60 results

Advanced filters: Author: Yitong Zhang Clear advanced filters

METTL3 abrogation promotes glioma progression through regulating the ISG15-FASN axis-mediated lipid metabolism in macrophages

Tumor-associated macrophages play central roles in the cellular immune response in the tumor microenvironment. Here the authors implicate the m6A methyltransferase METTL3 in glioma progression by regulation of the ISG15/FASN modulated lipid metabolism in macrophage.

Huilong Yin
Xiaoyi Yu
Rui Zhang
ResearchOpen Access08 Jan 2026
Nature Communications

P: 1-16
TransBrain: a computational framework for translating brain-wide phenotypes between humans and mice

TransBrain translates brain phenotypes between mouse and human via homology mapping, thus making it possible to capitalize on the wealth of knowledge about the mouse brain and gain insights into the human brain.

Shangzheng Huang
Tongyu Zhang
Ang Li
Research29 Dec 2025
Nature Methods

P: 1-12
High-fidelity unfolding of ²⁵²Cf neutron spectra in EJ-301 scintillators via calibrated response matrices and Monte Carlo simulations

Songbai Zhang
Yitong Qin
Xiaobo Liu
ResearchOpen Access27 Nov 2025
Scientific Reports

Volume: 16, P: 1-11
Stabilization of AFF1 by PARylation ensures transcriptional restart after DNA damage

Zhu, Fu, Zhu, Li and colleagues found that the key DNA repair enzyme poly(ADP-ribose) polymerase 1 promotes transcriptional restart after DNA damage through PARylating and stabilizing AFF1 by preventing its ubiquitylation by the E3 ligase Siah1.

Feifeng Zhu
Huanyi Fu
Huasong Lu
Research08 Oct 2025
Nature Chemical Biology

P: 1-14
Study on the survival prognosis of over 80 years old patients of esophageal cancer with other cancers-based on SEER data analysis

Qiaofang Li
Mengchang Gao
Xiaolu Yan
ResearchOpen Access28 Dec 2025
Scientific Reports

Volume: 16, P: 1-15
Ideal topological flat bands in chiral symmetric moiré systems from non-holomorphic functions

Recent studies on topological flat bands and their fractional states have suggested an analogy between moiré flat bands and Landau levels (LLs). Here, the authors describe a family of single component wavefunctions that cannot be written in a form similar to the Laughlin ansatz, implying that moiré flat bands are fundamentally different from LLs and this analogy has fundamental limits.

Siddhartha Sarkar
Xiaohan Wan
Kai Sun
ResearchOpen Access01 Aug 2025
Nature Communications

Volume: 16, P: 1-7
Construction of innovation literacy indicator system for medical college students and analysis of current situation based on a cross-sectional observation in China

Ronghang Liu
Xiuqing Li
Chunlei Han
ResearchOpen Access05 Dec 2025
Humanities and Social Sciences Communications

Volume: 13, P: 1-8
Correction: MMDental - A multimodal dataset of tooth CBCT images with expert medical records

Chengkai Wang
Yifan Zhang
Yaqi Wang
Amendments and CorrectionsOpen Access05 Aug 2025
Scientific Data

Volume: 12, P: 1
A method for characterizing and analyzing the structural behavior of concrete dams in cold regions

Xiao Fu
Maomei Wang
Chongshi Gu
ResearchOpen Access19 Dec 2025
Scientific Reports

Volume: 16, P: 1-23
Integration of transcriptomics and metabolomics reveals the mechanism of Lycium barbarum polysaccharides inhibited MCF-7 cell proliferation

Liyang Ding
Yitong Shang
Xing Du
ResearchOpen Access23 Nov 2025
Scientific Reports

Volume: 15, P: 1-14
Prediction of protein subcellular localization in single cells

Prediction of Unseen Proteins’ Subcellular localization (PUPS) combines a protein language model and an image inpainting model to utilize both protein sequence and cellular images for predicting protein localization on unseen proteins in a way that captures single-cell variability and cell-type specificity.

Xinyi Zhang
Yitong Tseo
Caroline Uhler
Research13 May 2025
Nature Methods

Volume: 22, P: 1265-1275
Catalytic activity of violet phosphorus-based nanosystems and the role of metabolites in tumor therapy

Reactive oxygen species (ROS)-based nanocatalytic cancer therapy is hindered by insufficient substrates at the tumor site and potential side effects arising from metabolites. Here the authors report a violet phosphorus-based nanosystem that supplies catalysts and substrates for producing cytotoxic ROS and generates the degradation products that can promote tumor calcification.

Hanjie Zhang
Yitong Zhang
Lin Mei
ResearchOpen Access08 Aug 2024
Nature Communications

Volume: 15, P: 1-17
Rapid lateral flow immunoassay for the fluorescence detection of SARS-CoV-2 RNA

A nucleic acid immunoassay implemented on a lateral flow strip accurately detects SARS-CoV-2 RNA in less than one hour via a fluorescence readout.

Daming Wang
Shaogui He
Yuguo Tang
Research03 Dec 2020
Nature Biomedical Engineering

Volume: 4, P: 1150-1158
Transcriptome-wide Mendelian randomization and single-cell analysis during CD4⁺ T cell activation deciphers immunotherapeutic targets for colorectal cancer

Kai Cui
Qiuming Zou
Qi Qi
ResearchOpen Access29 Dec 2025
npj Precision Oncology

Volume: 10, P: 1-15
SR-A3 suppresses AKT activation to protect against MAFLD by inhibiting XIAP-mediated PTEN degradation

Scavenger receptor class A member 3 (SR-A3) is implicated in metabolic diseases, but its relationship with MAFLD remains unclear. Here, the authors show that SR-A3 is an important modulator of hepatic energy metabolism and is a potential therapeutic target against MAFLD.

Pingping Lai
Guolin Miao
Xunde Xian
ResearchOpen Access11 Mar 2025
Nature Communications

Volume: 16, P: 1-18
SynGFN: learning across chemical space with generative flow-based molecular discovery

A persistent gap from theoretical molecules to experimentally viable compounds has hindered the practical adoption of generative algorithms. This study proposes SynGFN as a bridge linking molecular design and synthesis, accelerating exploration and producing diverse, synthesizable, high-performance molecules.

Yuchen Zhu
Shuwang Li
Chang-Yu Hsieh
Research13 Nov 2025
Nature Computational Science

Volume: 6, P: 29-38
Methylammonium-free, high-efficiency, and stable all-perovskite tandem solar cells enabled by multifunctional rubidium acetate

The high trap density associated with tin (II) oxidation impacts the device performance of methylammonium cation-free tin-lead perovskite solar cells. Here, authors employ rubidium acetate for defect passivation and achieve efficient and stable single-junction and all-perovskite tandem solar cells.

Xufeng Liao
Xuefei Jia
Jinhui Tong
ResearchOpen Access30 Jan 2025
Nature Communications

Volume: 16, P: 1-9
Relationship between family functioning and psychological distress among young and middle-aged patients with stroke: a moderated mediation model

Shumei Zhuang
Yannan Chen
Fengjuan Lei
ResearchOpen Access23 Nov 2025
Scientific Reports

Volume: 15, P: 1-13
ROFI: a deep learning-based ophthalmic sign-preserving and reversible patient face anonymizer

Yuan Tian
Min Zhou
Xianqun Fan
ResearchOpen Access20 Nov 2025
npj Digital Medicine

Volume: 8, P: 1-17
Buried interface molecular hybrid for inverted perovskite solar cells

High efficiency in perovskite solar cells is achieved by using a molecular hybrid of a self-assembled monolayer with nitrilotribenzoic acid.

Sanwan Liu
Jingbai Li
Wei Chen
Research26 Jun 2024
Nature

Volume: 632, P: 536-542
Surface chemical polishing and passivation minimize non-radiative recombination for all-perovskite tandem solar cells

The efficiency of all-perovskite tandem solar cells is impacted by the nonradiative recombination loss in Sn–Pb mixed narrow bandgap perovskite films. Here, the authors utilize a surface polishing agent with surface passivator to deliver films with a close-to-ideal stoichiometric ratio surface.

Yongyan Pan
Jianan Wang
Wei Chen
ResearchOpen Access26 Aug 2024
Nature Communications

Volume: 15, P: 1-10
A kinase fusion protein from Aegilops longissima confers resistance to wheat powdery mildew

The powdery mildew resistance gene Pm13 was introgressed into wheat from Aegilops longissima. Here, the authors report the cloning of Pm13 and reveal that it encodes a MLKL_NTD domain-containing kinase.

Huagang He
Zhaozhao Chen
Yajun Wang
ResearchOpen Access02 Aug 2024
Nature Communications

Volume: 15, P: 1-13
Cultural participation and psychological wellbeing: the mediating role of transcendence

Yitong Huang
Qixuan He
Benqian Li
ResearchOpen Access16 Aug 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-11
NKAPL facilitates transcription pause-release and bridges elongation to initiation during meiosis exit

Transcription elongation is an essential step for gene expression control but remains unclear during spermatogenesis. Here, the authors report that NKAPL, a testis-specific protein distantly related to RNA splicing factors, is a crucial regulator of transcription pause-release.

Zhenlong Kang
Chen Xu
Lan Ye
ResearchOpen Access17 Jan 2025
Nature Communications

Volume: 16, P: 1-20
Experimental investigation on the mechanism of the effect of flow velocity on Cyclotella meneghiniana

Jianwei Zhang
Hongdong Ma
Sitong Guo
ResearchOpen Access21 Mar 2025
Scientific Reports

Volume: 15, P: 1-10
Oral administration of garlic-derived nanoparticles improves cancer immunotherapy by inducing intestinal IFNγ-producing γδ T cells

γδ T cell-based immunotherapies are limited by the reduced expansion and activation of the T cells ex vivo. Here the authors show that garlic nanoparticles can activate IFNγ-producing γδ T cells directly in the intestine, before they translocate to extraintestinal tumours, where they can synergize with anti-PD-L1 therapy, inducing robust antitumour immunity.

Jialu Xu
Yue Yu
Chao Wang
Research25 Jul 2024
Nature Nanotechnology

Volume: 19, P: 1569-1578
Enabling robust blue circularly polarized organic afterglow through self-confining isolated chiral chromophore

The preparation of systems that give blue circularly polarised organic afterglow is desirable but challenging. Here, the authors confine a chiral chromophore within a polymer matrix to limit non-radiative transitions and give blue circularly polarised organic afterglow.

Mingjian Zeng
Weiguang Wang
Wei Huang
ResearchOpen Access09 Apr 2024
Nature Communications

Volume: 15, P: 1-10
A chaperone-like function of FUS ensures TAZ condensate dynamics and transcriptional activation

Shao et al. report that FUS interacts with the transcriptional coactivator TAZ, maintaining liquid-like properties of TAZ biomolecular condensates and enhancing TAZ transcriptional activity.

Yangqing Shao
Xin Shu
Huasong Lu
Research03 Jan 2024
Nature Cell Biology

Volume: 26, P: 86-99
Remote limb ischemic preconditioning alleviated spinal cord injury through inhibiting proinflammatory immune response and promoting the survival of spinal neurons

Yitong Yan
Zihan Li
Yan Yu
Research17 Aug 2024
Spinal Cord

Volume: 62, P: 562-573
The impacts of nonnegative doctor portrayals on public evaluations and professional attractiveness in medicine

Qiwei Li
Zhefei Mao
Jie Zhou
ResearchOpen Access26 Sept 2025
Scientific Reports

Volume: 15, P: 1-10
Psoralen induced cell cycle arrest by modulating Wnt/β-catenin pathway in breast cancer cells

Xiaohong Wang
Chengfeng Xu
Zhenlin Yang
ResearchOpen Access18 Sept 2018
Scientific Reports

Volume: 8, P: 1-7
Upregulation of KLHL17 promotes the proliferation and migration of non-small cell lung cancer by activating the Ras/MAPK signaling pathway

Non-small cell lung cancer (NSCLC) is the most common type of lung cancer and is associated with limited treatment options. This study elucidates the role of KLHL17 in the development and progression of NSCLC using clinical samples and NSCLC cell lines. The results show that upregulated KLHL17 in NSCLC promotes the proliferation and migration of tumor by activating Ras/MAPK signaling pathway, and suggest that KLHL17 may be a novel therapeutic target for the treatment of NSCLC.

Zongang Liu
Mengnan Zhao
Xueshan Qiu
Research17 Aug 2022
Laboratory Investigation

Volume: 102, P: 1389-1399
SUMOylation inhibitors synergize with FXR agonists in combating liver fibrosis

FXR agonists have been investigated for the treatment of non-alcoholic steatohepatitis and liver fibrosis but the clinical efficacy is not optimal. Here the authors show that enhanced FXR SUMOylation in activated hepatic stellate cells reduces FXR signaling and that this can be rescued by SUMOylation inhibitors.

Jiyu Zhou
Shuang Cui
Haiping Hao
ResearchOpen Access13 Jan 2020
Nature Communications

Volume: 11, P: 1-16
The effect of pH on the acute toxicity of phenanthrene in a marine microalgae Chlorella salina

Haigang Chen
Zhe Zhang
Xiaoping Jia
ResearchOpen Access04 Dec 2018
Scientific Reports

Volume: 8, P: 1-8
First-line camrelizumab (a PD-1 inhibitor) plus apatinib (an VEGFR-2 inhibitor) and chemotherapy for advanced gastric cancer (SPACE): a phase 1 study

Xiaofeng Chen
Hao Xu
Yongqian Shu
ResearchOpen Access25 Mar 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-8
A Facile Strategy to Prepare Dendrimer-stabilized Gold Nanorods with Sub-10-nm Size for Efficient Photothermal Cancer Therapy

Xinyu Wang
Hanling Wang
Yiyun Cheng
ResearchOpen Access09 Mar 2016
Scientific Reports

Volume: 6, P: 1-10
Plasma proteomic biomarkers predict therapeutic responses in advanced biliary tract cancer patients receiving Camrelizumab plus the GEMOX treatment

Shiyun Cui
Hejian Zheng
Xiaofeng Chen
ResearchOpen Access07 Apr 2025
npj Precision Oncology

Volume: 9, P: 1-12
A joint deep learning model to recover information and reduce artifacts in missing-wedge sinograms for electron tomography and beyond

Guanglei Ding
Yitong Liu
Huolin L. Xin
ResearchOpen Access05 Sept 2019
Scientific Reports

Volume: 9, P: 1-13
Artistic heritage conservation: the relevance and cultural value of Guangzhou clan building paintings to traditional rituals from a kinship perspective through perceptual assessment and data mining

Weicong Li
Shangbing Ma
Jinghui Ao
ResearchOpen Access25 Jun 2024
Heritage Science

Volume: 12, P: 1-19
A modified TOPSIS algorithm for the assessment of sports quality in higher education using circular pythagorean fuzzy information

Jiapeng Li
Yitong Zhang
ResearchOpen Access29 May 2025
Scientific Reports

Volume: 15, P: 1-16
Structural characteristics of corrugated sandwich rectangular pressure vessels

Lingxue Zhu
Yuan Fang
Xiaofeng Lu
ResearchOpen Access27 Mar 2025
Scientific Reports

Volume: 15, P: 1-22
AR to GR switch modulates differential TDO2-Kyn-AhR signalling to promote the survival and recurrence of treatment-induced dormant cells in prostate cancer

Sangsang Li
Yifan Zhang
Hailiang Hu
ResearchOpen Access05 Aug 2025
Cell Discovery

Volume: 11, P: 1-16
Alcohol-induced C/EBP β-driven VIRMA decreases oxidative stress and promotes pancreatic ductal adenocarcinoma growth and metastasis via the m6A/YTHDF2/SLC43A2 pathway

Lei Gao
Gaoyuan Lv
Yuhua Zhang
Research03 Feb 2025
Oncogene

Volume: 44, P: 1118-1132
Automatic retinoblastoma screening and surveillance using deep learning

Ruiheng Zhang
Li Dong
Wenbin Wei
Research21 Jun 2023
British Journal of Cancer

Volume: 129, P: 466-474
Age-related alterations in gut homeostasis are microbiota dependent

Yingli Jing
Qiuying Wang
Yan Yu
ResearchOpen Access25 Mar 2025
npj Biofilms and Microbiomes

Volume: 11, P: 1-14
Unveiling disulfidptosis-related biomarkers and predicting drugs in Alzheimer’s disease

Lei Huang
Zhengtai Li
Changyuan Yu
ResearchOpen Access30 Aug 2024
Scientific Reports

Volume: 14, P: 1-12
Characterization of changes in the resting-state intrinsic network in patients with diabetic peripheral neuropathy

Dongsheng Zhang
Yang Huang
Jie Gao
ResearchOpen Access21 Nov 2024
Scientific Reports

Volume: 14, P: 1-11
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease

Dongfeng Gu and colleagues report a genome-wide association study for coronary artery disease in Han Chinese individuals. They identify four loci newly associated with coronary artery disease.

Xiangfeng Lu
Laiyuan Wang
Dongfeng Gu
Research01 Jul 2012
Nature Genetics

Volume: 44, P: 890-894
MMDental - A multimodal dataset of tooth CBCT images with expert medical records

Chengkai Wang
Yifan Zhang
Yaqi Wang
ResearchOpen Access09 Jul 2025
Scientific Data

Volume: 12, P: 1-11
An empirical model of soft bellows actuator

Zhe Qiu
Shengyang Zhang
Zhongkui Wang
ResearchOpen Access19 Nov 2024
Scientific Reports

Volume: 14, P: 1-19

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