Plasma cells (PC) contribute to the pathogenesis of autoimmune diseases by secreting autoantibodies. Strategies to target pathogenic PCs are thus required. Here, the authors profile different PC subsets in naïve and lupus-prone mice and report the emergence and expansion of a CD19– PC subset in diseased mice that could compromise the effectiveness of CD19-targeting therapies.
- Van Duc Dang
- Franziska Szelinski
- Andreia C. Lino
