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A dual interfacial hydrogen-bond passivation strategy and a hybrid copper–iodide are used to fabricate deep-blue light-emitting diodes with excellent external quantum efficiency and lifetime.

Metal–ligand synergistic catalysis remains underexplored in single-atom systems. Here, inspired by homogeneous pincer complexes, the authors construct Pd(II)–N₄ sites on carbon nitride, enabling highly selective photocatalytic semi-hydrogenation of alkynes.

Multislice electron ptychography reveals that gradient-distributed ions induce progressive lattice distortions from bulk to surface, driving monoclinic γ-WO3 electrochromic materials to transform into tetragonal and cubic phases and forming the gradient-distributed colour centers.

Conventional ammonia synthesis is energy intensive. Here the authors explore the mechanism of light-driven ammonia synthesis through in situ spectroscopy and modelling, and demonstrate that certain AuRu plasmonic alloys are promising catalysts for this potentially more sustainable process.

Liu et al. report Chinese normative lifespan brain charts showing later neurodevelopmental milestones than those detected in Western cohorts. Individual deviations from these norms are valuable in assessing clinical risk and outcomes.

Microgravity triggers carotid artery aging via SREBP1. This lipid regulator remodels chromatin by boosting acetyl-CoA, silencing contractile genes while activating aging pathways. Targeting SREBP1 blocks senescence, revealing a therapeutic strategy for spaceflight-associated vascular remodeling.

Plants utilize anion channels to adapt to environmental stresses. Here, authors elucidate the coordinated regulatory mechanisms within the SLAH family and demonstrate that tRNA molecules directly bind to and inhibit the SLAH1 anion channel.

The paper demonstrates a ferroelectric photosensor array that integrates image memorization, low-level processing, and high-level computing. It uses dynamic and switchable photovoltages to perform image tasks, leveraging the bulk photovoltaic effect for enhanced precision and reliability.

Conjugated microporous polymers are highly flexible materials that may be used for gas storage and catalysis applications. Here, the authors report metal-functionalized conjugated microporous polymers capable of both capturing CO₂and functioning as a heterogeneous catalyst in its conversion to propylene carbonate.

The disordered molecular aggregation of non-fullerene acceptors in nonhalogenated solvents limits the performance of organic solar cells. Here, the authors apply an ultrasound field to induce J aggregation of molecules, achieving maximum efficiency of 20.41% for o-xylene-processed ternary devices.

The authors develop a super-gravity field remelting fabrication technology which is effective in synergistically optimizing the electrical and thermal transport properties. Under a super-gravity field, the brittle (Bi,Sb)₂Te₃ alloy undergoes unusual plastic deformation during melt solidification.

Ring-opening reactions of bicyclo[1.1.0]butanes (BCBs) provide a reliable platform for synthesizing functionalized cyclobutanes, Herein, the authors report a catalyst-controlled, regiodivergent α- and β‘-selective hydrophosphination of acyl BCBs.

Global vegetation growth peaks have been increasing over recent decades, but grasslands are highly sensitive to climate, and it is unclear whether this upward trend can be sustained. This study shows that over the past four decades, decadal droughts have temporarily disrupted this global increase in grassland peak productivity.

The nature of the pairing symmetry in superconducting single-layer FeSe has been the subject of intense debate. Here, the authors use scanning tunneling microscopy/spectroscopy to show the absence of topological edge/corner modes, providing evidence for sign-preserving s-wave pairing.

Organic luminescent materials attract attention due to their wide application range, but many organic luminogens suffer from severe quenching effect in the aggregate state. Here, the authors demonstrate a macrocyclization induced emission enhancement by linking luminophores through methylene bridges to give a macrocycle.

This work assesses the enrichment and organification of tritium by algae and the transfer along the marine food chain, suggesting human health risks and highlighting the importance of radioactive isotope management.

The unique band structure of topological insulators gives rise to insulating bulk and unusual metallic surface properties. By tuning the content of Sb in the ternary compound (Bi_1–xSb_x)₂Te₃, Wang and collaborators show it is possible to control the precise features of the band structure in a continuous fashion.

The development of moderate magnetic hyperthermia (MH) for tumor ablation while concurrently restoring bone homeostasis shows potential for osteosarcoma (OS) therapy. Here this group combines magnetothermal nanoparticles with MH temperature-controlled borosilicate bioactive glass achieving OS cell impair while activating TNF signaling pathway for therapeutic purpose.

A two-phase assembly approach is developed to synthesize single-unit-cell-thick perovskite chains within single-walled carbon nanotubes. A direct X-ray detector constructed with the confined perovskite chains exhibits outstanding performance and ultrahigh stability under harsh conditions.

Fang and colleagues show that the metabolite succinate can inhibit succinylation, and consequently protection from ubiquitin-mediated degradation, of the transcription factor FOXP3, with consequences on T_reg cell-suppressive function and IBD pathology.

This study collected and analysed 3,517 de novo assemblies from 1,575 plant species sequenced since 2000, including 793 newly sequenced species in the past three years. A database named N3: plants, genomes, technologies was developed to accommodate the metadata associated with the sequenced genomes.

Diarrhoea is a major cause of morbidity and mortality in China. Here, the authors present results from a large sentinel surveillance scheme from 217 hospitals in all 31 provinces in mainland China, including ~150,000 patients with acute diarrhoea and covering years 2009-2018.

China operates a national surveillance program for acute respiratory infections and sampled over 200,000 patients between 2009–2019. Here, the authors present results from this program and describe patterns by age, pathogen type, presence of pneumonia, and season.

Lipoylated proteins are essential for energy metabolism of both prokaryotes and eukaryotes. Here, the authors showed that the E. coli lipoate-protein ligase A (LplA) can boost the lipoylation of key energy metabolism enzymes of diverse organisms.

Xiao, Woodham, Cui, et al. apply machine learning to brain MRI data from major depression and the UK Biobank. They identify two neuroanatomical dimensions, one linked to preserved brain structure and healthier outcomes, and the other to reduced volumes, impaired cognition, self-harm, and adverse metabolic and genetic profiles.

A cross-sectional study of hospitalized patients with COVID-19 and a longitudinal follow-up study of patients with COVID-19 suggest that SARS-CoV2-specific IgG or IgM seroconversion occurs within 20 days post symptom onset.

Multi-chambered structures have attracted great attention due to their ability to create multifunctional partitions in different chambers. Here, the authors prepared mesoporous silica nanoreactors with hierarchical chambers for catalytic cascades.

Succinylation, a posttranslational modification on lysine residues, is involved in tumor progression. Here, authors show that PDHA1 K83 succinylation is involved in cholangiocarcinoma tumorigenesis through regulation of macrophage antigen presentation in the tumor microenvironment

Tandem catalysts are important in electrocatalysis but suffer from uncontrollable interfaces, limited crystal phases, and complex synthesis. Here, the authors report the facile synthesis of hetero-phase 4H/fcc Au–Cu tandem catalysts with tunable interfaces for ammonia electrosynthesis from nitrate.

The solid-electrolyte interphase is crucial for most batteries, but its characterization is challenging. Here, authors develop a depth-sensitive plasmon-enhanced Raman spectroscopy method to enable in-situ and nondestructive resolving of its structure and chemistry as well as formation mechanisms.

Gao et al. identify a piRNA, CHAPIR, that targets the m⁶A methylation of PARP10 and promotes the GSK3β-induced accumulation of nuclear NFATC4, thereby modulating cardiac hypertrophy and heart function upon pressure overload.

The nickelates have received significant attention due to their proximity to the cuprates but there are still many unanswered questions about their underlying physics. Here, the authors apply DFT combined with dynamical mean field theory and density matrix embedding theory to determine the electronic structure of the infinite layer nickelate, La_0.8Sr_0.2NiO₂, where results indicate a d-wave superconducting ground state.

Base editors are genome engineering tools that can generate nucleotide substitutions without introducing double-stranded breaks. Here the authors show that a phage-derived peptidyl CRISPR inhibitor can be employed to modulate the activity and targeting scope of CRISPR base editor for precision base editing applications.

Enteroviruses are responsible for several human diseases without treatment. This study describes the molecular interactions between SETD3, actin, and viral 2A in viral replication, providing a framework for the development of host-targeted therapies against enteroviruses.

The authors study monolayer FeSe via scanning tunneling microscopy and simultaneous micron-scale-probe-based transport. They observe distinct superconducting phases in domains and on boundaries between domains, with different superconducting gaps and pairing temperatures.

Cryo-electron microscopy structures of a short prokaryotic Argonaute (pAgo) and the associated TIR-APAZ proteins bound by guide RNA and target DNA shed light on the mechanisms of assembly and activation of pAgo systems.