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Coupling two ionic thermoelectric effects in n-type materials is scarce, restricting the development of high-performance systems. Here, the authors present an ionic-thermoelectric material with interactive thermo-diffusion/galvanic coupling effect based on coordination chemistry.

Spin transport properties of magnetically ordered materials have been well studied. Here, the authors report an anomalous spin signal exhibiting spin transport over 480 microns in the frustrated hyperkagome magnetic insulator Gd₃Ga₅O₁₂.

The STAR experiment at the Relativistic Heavy Ion Collider at Brookhaven National Laboratory demonstrates evidence of spin correlations in \(\Lambda \bar{\Lambda }\) hyperon pairs inherited from virtual spin-correlated strange quark–antiquark pairs during QCD confinement.

Identifying jets originating from heavy quarks plays a fundamental role in hadronic collider experiments. In this work, the ATLAS Collaboration describes and tests a transformer-based neural network architecture for jet flavour tagging based on low-level input and physics-inspired constraints.

Mitochondrial superoxide production is shown to preserve nuclear envelope integrity by controlling lipid peroxidation, with impact on nuclear and organismal ageing in C. elegans.

There has been a recent interest in control of magnetism via ionic transport. The appeal of such magneto-ionic control lies in its extent, non-volatility and potential energy-efficiency, however, the number of systems showing such behaviour is limited. Here, Tan, Ma, and coauthors demonstrate magneto-ionic control through Carbon transport.

Fracto-mechanoluminescence is the emission of light from fracturing solids. Here, the authors show that this emission in Mn halides arises from elastic stiffness, electromechanical coupling, and trap states that activate Mn²⁺ d−d transitions.

Humanity’s Last Exam, a multi-modal benchmark at the frontier of human knowledge, is designed to be an expert-level closed-ended academic benchmark with broad subject coverage.

The authors study a topological insulator (TI) sandwiched between two magnetic TIs. By keeping one of the magnetic TIs insulating, while tuning the other one into a metallic regime, they find half quantized anomalous Hall conductance, a boundary signature consistent with a quantized axion field.

Native crystallographic defects are often introduced during synthesis of battery materials, but has been overlooked. Here, using in situ synchrotron X-ray probes and electron microscopy, the authors have revealed their adverse effect during battery operation.

MnBi₂Te₄ has an appealing combination of topological bands and magnetic ordering. While chemical doping with Sb can be used to tune these properties, it typically comes with an increase in defect density. Here, Chen, Wang, Li, Duan, and coauthors demonstrate a defect engineering approach that preserves the topological and magnetic properties of Mn(Bi_1-xSb_x)₂Te₄.

The CMS Collaboration reports the measurement of the spin, parity, and charge conjugation properties of all-charm tetraquarks, exotic fleeting particles formed in proton–proton collisions at the Large Hadron Collider.

Examples of materials with non-trivial band topology in the presence of strong electron correlations are rare. Now it is shown that quantum fluctuations near a quantum phase transition can promote topological phases in a heavy-fermion compound.

The authors report the synthesis of (La_0.9Y_0.1)H₁₀ superhydrides and their characterization using synchrotron-based, spatially resolved x-ray diffraction and electrical transport imaging. They reveal μm-scale structural inhomogeneity with coexisting cubic and hexagonal clathrate phases exhibiting distinct superconducting transition temperatures.

A mechano-intelligent transmission mechanism based on the slipknot delivers precise force signals for clinical practice and robotic operations such as minimally invasive surgery and tendon-driven robotics.

Mechanical recycling of incompatible mixed plastics is challenging, as it often downcycles plastics into brittle materials. Here the authors develop a multi-arm topological universal dynamic crosslinker platform to enable mechanical upcycling of incompatible mixed plastics.

The coexistence of ferroelectricity and nonreciprocal transport in metallic material has been a challenge. The authors demonstrate that the polarity-induced nonreciprocal transport can be nonvolatile and electrically reversed in ferroelectric polar metal WTe₂.

Precise editing of DNA methylation has emerged as a promising tool in disease biology but most applications are limited to in vitro systems. Here, we develop two transgenic mouse lines harboring an inducible dCas9-DNMT3A or dCas9-TET1 editor to enable tissue-specific DNA methylation editing in vivo.

Extracellular vesicles (EVs) have shown potential as a therapeutic delivery system for cancer treatment. In here the authors have established HEK293T cells engineered with α-HLA-G VHH antibody-chimeric CD63 protein to promote the production of EVs that can augment the targeting of HLA-G-positive tumor cells

The Einstein Probe has discovered a fast X-ray transient, EP240414a, associated with a broad-lined type Ic supernova. Its unusually soft spectrum and weak jet add to the diversity of stellar deaths and suggest a previously unknown Wolf–Rayet star explosion mechanism.

Genomic analyses applied to 14 childhood- and adult-onset psychiatric disorders identifies five underlying genomic factors that explain the majority of the genetic variance of the individual disorders.

Indonesian cattle are unique due to their history of admixture involving both zebu and banteng. Here, Wang et al. identify ~3.5 million novel introgressed SNP variants and provide a genomic map of banteng introgression within and across many cattle breeds, each with unique introgression histories.

Using Canada’s National Forest Inventory, this study shows boreal understory plant communities are shifting, species richness rises while evenness falls. These changes track warming, nitrogen deposition and moisture, and are moderated by canopy cover.

The ALICE Collaboration provides details on the microscopic mechanism that ends up creating antideuteron in high-energy proton–proton collisions at the Large Hadron Collider.

An approach that integrates electrochemical CO₂ reduction and biological denitrification provides a new solution for nitrogen removal, where the formate obtained from CO₂ is used directly as the carbon source in the denitrification process in wastewater treatment.

Mutations in the PBAF chromatin-remodeling complex cause various neurodevelopmental disorders. This study shows that PBAF shapes distinct motor neuron identities, revealing how its disruption impairs movement and offering insight into neurodevelopmental disorders caused by PBAF mutations.

Combined behavioural, circuit-level and cellular approaches are used to demonstrate how hypothalamic neurons integrate hunger and oestrous state to drive a switch in how female mice interact with pups.

Therapeutic gene editing in vivo is an ongoing challenge. Here, authors demonstrate Cas9 nickase guided DNA ligation as a nonviral method for installing permanent genomic corrections with favorable on target edit profiles in model animal cell types and adult mice.

The quark structure of the f₀(980) hadron is still unknown after 50 years of its discovery. Here, the CMS Collaboration reports a measurement of the elliptic flow of the f₀(980) state in proton-lead collisions at a nucleon-nucleon centre-of-mass energy of 8.16 TeV, providing strong evidence that the state is an ordinary meson.

JWST/NIRSpec observations of the 49 Ceti debris disk reveal spatially resolved, fluorescently excited CO emission, indicating a secondary origin of the gas in debris disks (that is, from the collision of volatile-rich bodies).

Data obtained from the MicroBooNE liquid-argon time projection chamber are used to exclude the single light sterile neutrino interpretation of the LSND and MiniBooNE anomalies at the 95% confidence level.

Engineered polar nanoclusters in tin-doped barium titanate thin films enable microwave tunability of ~74% at 6 GHz under low bias, offering a strategy to achieve high tunability with minimal dielectric loss for microwave communication.

A CRISPR knock-in strategy that uses endogenous gene regulatory mechanisms can engineer ‘armoured’ CAR T cells that secrete proinflammatory cytokines directly within a tumour without causing toxicity, leading to prolonged survival in mice.

This study leverages plasma proteomics from over 50,000 individuals to build organ-specific aging models and uncover underlying genetic mechanisms. It also investigates causal links between organ aging, diseases, and lifestyle, providing insights for promoting healthy longevity.

The death of massive stars has traditionally been discovered by explosive events in the gamma-ray band. Liu et al. show that the sensitive wide-field monitor on board Einstein Probe can reveal a weak soft-X-ray signal much earlier than gamma rays.

Immune checkpoint inhibitors have shown promise in tumour immunotherapy but resistance has been seen. Here using pre-treatment hepatocellular carcinoma patient biopsies from patients scheduled for immunotherapy, the authors implicate BCL9 and show that a BCL9-targeting peptide promotes anti-tumour immunity in mouse models through targeting macrophages and promoting anti-tumour T cell responses.

Multi-ancestry genome-wide association meta-analyses of polycystic ovary syndrome in women of East Asian and European ancestries identify 94 independent susceptibility regions, including 73 novel loci.

Managing power exhaust in fusion reactors is a key challenge, especially in compact designs for cost-effective commercial energy. This study shows how alternative divertor configurations improve exhaust control, enhance stability, absorb transients and enable independent plasma regulation.

The development of neural interfaces at subcortical nuclei surfaces is challenging. The authors present a flexible, minimally invasive neural interface that self-unfolds in cerebrospinal fluid to conform to periventricular surfaces, enabling long-term monitoring of deep brain disorders.

Long-lasting oxygen catalysts are crucial for rechargeable zinc-air batteries. Here, the authors report that placing tungsten atoms next to iron atoms within N₄ units creates durable Fe-N₄/W-N₄ diatomic sites, enabling a zinc-air battery to cycle reliably for more than 10,000 h.

3D correlative nanoscale tomography on an Fe-W alloy shows that topology requires secondary grain boundary dislocations which strongly control patterned solute segregation, reshaping segregation energy spectra and opening routes for advanced alloy design.

Zinc-ion batteries face challenges like dendrite formation, limiting their performance. Here, authors reveal that high-current deposition forms (002) textured Zn, enhancing cycling life, and propose guidelines for optimizing battery cycling protocols based on advanced in situ XRD analysis.

Thermal lepton pairs are ideal probes for the temperature of quark-gluon plasma. Here, the STAR Collaboration uses thermal electron-positron pair production to measure quark-gluon plasma average temperature at different stages of the evolution.

An extreme flare has been seen from a supermassive black hole at redshift z = 2.6. First detected in 2018, it is 30 times brighter than similar events. The most likely cause is the shredding of a star of 30 solar masses or more.

The development of fast-charging and high-capacity negative electrodes is critical for advanced lithium-ion batteries. Here, authors use a vacancy engineering strategy to develop a layered Prussian blue analogue with competitive rate capability, delivering a specific capacity of 510 mAh g⁻¹ at a specific current of 8 A g⁻¹.

Coastal settlement retreat reflects human behavioural adaptation to increasing coastal climate hazards. Using night-time light data over 1992–2019, this study finds that over half of global coastal settlements have retreated, driven by insufficient infrastructure protection and adaptive capacity.

This study presents a programmable mRNA nanomedicine that induces tumour-specific immunogenic cell death in immunologically cold and metastatic tumours with enhanced safety, advancing next-generation strategies for personalized cancer immunotherapy

Safe lithium-ion batteries require stable electrolytes with high chemical resistance and high thermal tolerance. Chen et al. find a solid lithium-salt electrolyte that is able to give rise to a prolonged battery life and a delayed decomposition of battery cathodes.