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A sequential deposition method combined with a multifunctional organic additive enables sky-blue all-thermally evaporated perovskite light-emitting diodes with a peak external quantum efficiency of 20.15%, as well as their integration into an active-matrix display prototype.

Researchers demonstrate a minimalist terahertz wireless transceiver in integrated photonics. They break the longstanding constraint between source purity and DSP complexity, realizing 144 Gbps high-speed transmission at subterahertz frequency.

Developing durable, water-repellent textiles without using harmful fluorinated chemicals is challenging. Here, authors use a one-step molecular assembly to covalently bond superhydrophobic silica shells directly onto fibers, resulting in high wear resistance and breathability.

The authors identify a KAT8 K145 lactylation switch that enhances TIP60 dependent p53 K120 acetylation and proapoptotic transcription, implicating this axis in doxorubicin cardiotoxicity and its mitigation by glimepiride.

Direct C–N bond formation from nitroarenes offers an appealing alternative to conventional routes that rely on aniline intermediates. Here, the authors report a paired electrolysis strategy that enables highly selective para-C–H amination of phenols with nitroarenes, delivering unprotected p-hydroxy diphenylamines in a single step without transition-metal catalysts or external reductants.

Ordered antihedgehog polar lattices are engineered in antiferroelectric PbZrO₃ thin films via interfacial dislocation networks. The authors reveal that these ordered topological structures originate from mismatch.

The switching behavior of oxide-based memristors is governed by uncontrolled formation and rupture of conductive filaments. Here Li et al. report a device with ultrathin elemental oxygen reservoir layer to regulate the random migration of oxygen vacancy, enabling switching speed of ~10 ns and high energy efficiency.

Axially chiral arylpyrroles hold significant promise in catalysis, medicinal chemistry and materials science. Here, the authors report a copper-catalyzed dynamic kinetic asymmetric (4 + 1) cyclization enabling atroposelective synthesis of arylpyrroles with single stereogenic axes or 1,2-diaxes from 1,3- enynes and amines.

Xia, Zhang, Peng, Chen et al. find that Leydig cells and macrophages show bidirectional mitochondrial transfer through extracellular vesicles, ensuring Leydig cells have functional mitochondria. The exchange is needed for testosterone production.

A dated phylogeny of 16,585 vascular plant species native to China reveals three major centres of endemism, including a potential new global biodiversity hotspot.

China’s crowded coasts must balance seafood demand with conserving migratory shorebirds that rely on tidal flats along the East Asian–Australasian Flyway. This study suggests that well-managed mariculture feeds shorebirds and limits overharvest, benefiting seafood production and biodiversity.

Measurement-based quantum computing implements quantum algorithms by performing sequences of measurements on special classes of entangled states, such as cluster states. This approach has now been demonstrated on a superconducting quantum processor.

An in situ computational spectrometer, implemented on a fully integrated 576-Kb memristor chip, can reconstruct a single spectrum in 125.0 ns and consumes only 6.7 nJ of energy, achieving software-equivalent accuracy.

Perovskite–organic-based solar cells typically show poor reverse-bias stability. By modulating the deep trap state in the bulk-heterojunction region, organic and perovskite–organic tandem solar cells show largely improved stability under reverse biases up to –40 V.

In mice, a circuit between the spinal cord and various regions of the brain, centring on spinal-cord-projecting neurons in the rostral ventromedial medulla, has a key role in driving chronic pain.

Traditional iterative catalysis in RiPP biosynthesis typically modifies linear peptides. Here the authors discover GNAT enzymes that iteratively modify fully folded lasso peptides and engineer them to create lipolasso peptides with expanded chemical diversity.

Technology advancement is essential for climate action, yet the uneven distribution of technological progress across the world can slow mitigation. Through empirical and scenario analysis, researchers find that participating in trade agreements could enhance technological transfers and lead to emission reductions.

The identification of ‘boosters’ that drive gene overexpression directly in a CAR construct provides a simple and scalable strategy for developing effective CAR-NK cell therapies for solid tumours.

Coupled homodimers of quantum dots can provide a platform for investigating quantum phenomena. Here, the authors synthesize homodimers in solution exhibiting two orthogonally polarized photoluminescence modes with two distinct types of biexcitons.

The authors mapped the continental-scale fraction of age-dependent leaf area index and revealed a widespread increase in the fraction of photosynthetically efficient young leaves across the majority of Amazon rainforests over the past decades.

Here, the authors show that a chiral plasmonic nanoparticle coupled to monolayer MoS₂ creates a magnetic-field-free 19 meV valley splitting and extends valley polarization lifetime at room temperature, paving the way to tunable, longer-lived valley-encoded dynamic control.

Brain metastases are a common complication of advanced non-small cell lung cancer (NSCLC) and affect responses to immune checkpoint inhibitors (ICI). Here the authors perform single cell transcriptomics on samples from NSCLC and brain metastases and implicate transcriptomic signatures associated with responsiveness to ICI.

Bioresorbable piezoelectric materials are key for bioelectronic–tissue integration but remain challenging to realize. Here, the authors develop flexible Rochelle salt/PLLA nanofibers that enable effective nerve regeneration and wireless monitoring of intestinal motility.

Nonlinear optical micropolarimetry and atomistic Monte Carlo simulations of monolayer NiPS₃ evidence a Berezinskii–Kosterlitz–Thouless phase that, with decreasing temperature, gives way to long-range order consistent with a six-state clock model.

Increased glycolysis in pancreatic cancer promotes immune escape by altering the tumor microenvironment. Here, the authors show that lactate-driven histone lactylation via PCAF increases CXCL1 expression, recruiting neutrophils and enabling immunosuppression, and PCAF inhibition improves anti-PD-1 therapy in pancreatic cancer mouse models.

Strong paramagnetism is generated in hydrogels rich in carbon–oxygen double bonds simply by coupling with diamagnetic Ca cations. These paramagnetic hydrogels are applied as magnetic resonance imaging contrast agents and magnetic drug carriers.

ASXL1 is often mutated in myeloid cancers. Here, the authors describe the molecular and structural mechanism by which ASXL1 associates with the transcriptional coactivator BRD4, helping to explain their high correlation in cancers.

A model, trained to generate synthetic, patient-specific angiography images, reduced radiation exposure to patients and clinicians by two-thirds in a multicenter randomized controlled trial involving 1,068 patients.

Researchers report a solid that is amorphous in two dimensions but crystalline in the third, made of stacked disordered atomic layers. This shows that crystalline and amorphous order can coexist within a single material depending on direction.

Conversion-type batteries with high energy storage efficiency are important to minimize the energy loss during energy storage. Here, authors develop a rechargeable battery with a maximum energy storage efficiency of 99.5% based on S-Cl synergistic chemistry and Cl₂ mediating role.

Hong-Xuan Lin, Ji-Ping Gao, Jun-Xiang Shan and colleagues show that natural variation in a proteasome α2 subunit gene contributes to thermotolerance in African rice. Their follow-up studies suggest that the variant allele protects cells from heat stress by enhancing the elimination of cytotoxic denatured proteins and maintaining heat-response processes.

Xu et al. report that CDK10 drives immune evasion by reducing nucleic acid sensors-mediated innate immune response in tumor cells and that its inhibition improves response to immune-checkpoint blockade in preclinical cancer models.

This study reports ceramic nanowire aerogels with dual SiO₂/PyC nodes that combine high strength and elasticity, overcoming the typical strength–elasticity trade-off through a synergistic soft–hard structural design.

An integrated photonics scheme is presented for the manufacture of communication systems supporting the use of fibre and wireless infrastructures simultaneously, addressing the long-standing bandwidth mismatch between the two domains and demonstrating ultrahigh data rates.

Liu et al. report Chinese normative lifespan brain charts showing later neurodevelopmental milestones than those detected in Western cohorts. Individual deviations from these norms are valuable in assessing clinical risk and outcomes.

Freestanding membranes of hexagonal oxides remain difficult to obtain. In this work, a water-soluble crystalline hexagonal BaAl₂O₄ is found to serve as a sacrificial layer for obtaining freestanding membranes with six-fold or three-fold symmetry.

Arctic sea ice loss is reshaping the ocean’s carbon pump. Satellite data show an early boost, then stagnation, while models warn of future weakening under ice-free conditions, threatening carbon storage and ecosystems.

Surface plasmon-mediated steady-state and on-demand electronic spin modulation effectively activates light-driven plasmonic catalysis, facilitating polarization reactant activation and preferential reaction pathway modulation.