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The authors introduce nanoscale titanium layers to boost the flexibility of flexible thermoelectric device with 162 thin-film legs (p-Bi0.5Sb_1.5Te₃/n-Bi₂Te_2.7Se_0.3), achieving a high normalized power density >4 μW cm⁻² K⁻² and offering good flexibility.

Hall resistance quantization measurements in the quantum anomalous Hall effect regime on a device based on the magnetic topological insulator V-doped (Bi,Sb)₂Te₃ show that the system can provide a zero external magnetic field quantum standard of resistance.

The expansion of the photovoltaic industry has created dual challenges of resource supply and waste management. Here, the authors assess the potential of global anthropogenic mineral circularity from photovoltaic waste to mitigate these challenges.

To overcome limitations with anion dissolution, the authors design 2D FeTeSe nanosheets as electrocatalyst. The reaction-driven, in-situ generation of anisotropic in-plane tensile and out-of-plane compressive strains enhances the alkaline low-concentration nitrate reduction.

Here, Ma et al. investigate the translational profile of cardiac regeneration, pointing to Nat10 as a key regulator of cardiomyocyte proliferative potential, and describing how it regulates cardiac gene expression.

How landscapes are arranged affects soil pathogenic fungi worldwide. The authors reveal the global pattern and pronounced scale-dependency of landscape complexity and land-cover quantity on soil pathogenic fungal diversity.

Memristor arrays based on molecular crystal with van der Waals-linked cages are fabricated, enabling ultralow energy switching, high endurance and seamless integration into neuromorphic computing hardware.

Cytoplasmic mRNA translation contributes to the production of most chloroplast proteins. Here, the authors revealed that an interplay between Kozak motifs and HOT3/eIF5B1 controls the translation of nucleus-encoded chloroplast proteins.

Population genomics has primarily focused on sequence polymorphisms rather than gene expression diversity. Here, the conduct RNA-seq for 328 common wheat lines to investigate the role of gene expression variation in shaping agronomic traits and their contributions to modern wheat improvement.

Available intrinsic magnetic topological insulators are rare. Here, the authors study the electronic and magnetic properties of Mn(Sb_xBi_(1-x))₂Te₄ bulks and thin flakes, revealing intrinsic magnetic topological insulator phase in the phase diagram.

The authors fabricate a thermoelectric cooling device based on n-type PbS based material, which exhibits a remarkable cooling temperature difference of 36.9 K at room temperature, and the single-leg power generation efficiency of 8%.

Methanol on under-coordinated Pt sites at surface Te vacancies on layered PtTe2 decomposes at a probability >90 % which ultimately produces gaseous molecular hydrogen, methane, water and formaldehyde.

The sexually transmitted human parasite Trichomonas vaginalis belongs to a clade of host-switching trichomonads that parasitize mammals, birds, livestock, and pets. Here the authors describe a chromosome-scale genome for T. vaginalis and assemblies of other bird and mammal-infecting species, identifying gene functions implicated in the spillover of trichomonads from birds to humans.

SMC complexes are ring-shaped motors that fold DNA by extruding loops, but how they navigate large DNA obstacles is unclear. Here, Liu et al., show that SMC complexes bypass obstacles by threading obstacle linkers through a selective hinge channel, enabling translocation on crowded chromatin.

The magnetic exchange interaction of MnBi₂Te₄—an intrinsic magnetic topological insulator—can be tuned by intercalating ferromagnetic layers of MnTe.

A genus-level super-pangenome of Avena comprising 35 high-quality genomes from 23 cultivated or wild oat species highlights the evolution of Avena and the landscape of structural variations related to abiotic stress resistance.

Thinopyrum intermedium and Roegneria kamoji are wheat relatives commonly used in distant hybridization breeding program. Here, the authors report the genome assemblies of the two species and reveal their phylogenetic relationship and genome compositions.

Under normal conditions neither FeTe nor Bi₂Te₃ are superconductors, the former being a semiconductor and the latter a topological insulator. However, He et al. show that when a Bi₂Te₃layer, even down to one-quintuple-layer in thickness, is grown on FeTe, superconductivity develops at the interface.

Li, He, Liu and colleagues characterize the dynamic bivalent chromatin landscape during mouse peri-implantation development. They find that factor ZBTB17 works with KDM6A/B to resolve transiently maintained bivalent domains and prime gene activation.

Tian et al. reveal that rich temporal dynamics within individual brain regions form stable individual-specific ‘barcodes’, advancing generalizable brain-wide association studies beyond traditional connectivity measures.

The 4D Nucleome Project demonstrates the use of genomic assays and computational methods to measure genome folding and then predict genomic structure from DNA sequence, facilitating the discovery of potential effects of genetic variants, including variants associated with disease, on genome structure and function.

Intrinsic regulators of stem cell-based embryo models are understudied. Here, the authors show that Nr1h2 activation allows ESCs to form blastoids with better implantation and higher blastocyst rates via coactivator Kdm1a and the Nr1h2-SINE B1 axis.

Caspase 8 protein expression is largely absent in small cell lung cancer (SCLC) patients. Here, the authors generate a caspase 8 deletion SCLC mouse model and show that it promotes a neuronal progenitor-like cell state and pre-tumoral immunosuppression triggered by necroptosis that promotes metastasis.

Thermoelectric materials could reduce energy losses by converting waste heat from various processes into electricity. To cater to the needs of wearable devices, the authors design Bi₂Te₃-based thin films that show both excellent thermoelectric performance and long-sought flexibility.

Aberration of chromatin organisation is linked to cancer progression and cancer cell plasticity. Here, the authors investigate changes in chromatin state during the transition of cancer cells to cancer stem cells and, using a CTCF-cohesin contact reporter CRISPR screen, identify TLK2 as a driver of plasticity via regulation of chromatin loop formation.

Acetyl-CoA synthetases have been proposed as targets for development of new antimicrobial drugs. Here, Jezewski et al. identify isoxazole-based compounds with activity against the pathogenic fungus Cryptococcus neoformans, and describe their mechanism of action as inhibitors of fungal acetyl-CoA synthetases.

This study shows that the transcriptional targets of NANOG recruits UTP15 to gene promoters in mESCs. There, UTP15 supports the formation of Pol II condensates, thereby activating pluripotency gene transcription independently of its classic role.

The regulatory roles of structural variations (SVs) in transcriptional networks and agronomic traits of tea plants are largely unexplored. Here, the authors assemble the pangnome from 22 representative tea accessions and their wild relative and reveal SVs driving gene expression alteration and agronomic traits diversification.

The authors study (Bi,Sb)₂Te₃/FeTe bilayers, which feature emergent superconductivity at the interface with T_c ~ 12 K. Through angle-resolved photoemission spectroscopy and electrical transport measurements, they argue that the Dirac-fermion-mediated Ruderman-Kittel-Kasuya-Yosida-type interaction weakens antiferromagnetic order in FeTe layer, allowing for superconductivity.

The lack of desirable barrier layers prohibits the power generation applications of bismuth telluride thermoelectric devices. Here, the authors construct a kind of Ti barrier layer with high strength and low resistivity with a module exhibiting high thermal stability during the service at 523 K.

Authors report the entropy-modulated atomic ripple structure in Nb2CTe-based MXenes, realizing the controllable adjustment of electrical properties.

Using generative AI, Insilico Medicine developed an oral PROTAC that potently inhibits and degrades PKMYT1, a synthetically lethal target in cancer, demonstrating high selectivity and strong antitumor efficacy in preclinical models.

The authors find chemical bonding mechanisms play a key role in tailoring the solubility of dopants and improving the thermoelectric performance of metavalently bonded materials.

Weyl semimetals are interesting because they are characterized by topological invariants, but specific examples discovered to date tend to have complicated band structures with many Weyl points. Here, the authors show that TaIrTe₄ has only four Weyl points, the minimal number required by time-reversal symmetry.

Transposable elements (TEs) fulfill essential but poorly understood roles in genome organization and gene expression control. Here the authors show that the regulation of TEs occurs through overlapping epigenetic mechanisms that control the expression and chromatin signatures at TEs.

Heat stress can activate heterochromatin-associated transposon elements (TEs). Here, the authors show that heat stress leads to global rearrangement of 3D genome and TEs activation closely correlates with 3D chromatin organization rearrangement in Arabidopsis.

By using liquid metal electrodes and selectively doped self-healing materials, the authors make devices with high performance, modular assembly, and application potential in wearable electronics.