Search

Leveraging electron-phonon coupling allows for modulating self-trapped exciton formation for broadband white-light emission. Using transient spectroscopy and DFT calculations, Zhang et al. correlate the structural distortion with self-trapped exciton formation in 2D halide perovskites.

The longevity of leaves determines the overall duration of photosynthesis for plants. This study suggests that climate change drives leaf longevity convergence toward intermediate ranges, which, by altering leaf traits and enhancing photosynthetic capacity, strengthens ecosystem stability and is closely linked to vegetation diversity.

High sugar intake is a potential risk factor for heart failure, but there is insufficient evidence for the benefit of restricting sugar intake during pregnancy or early life. Using the end of UK sugar rationing as a natural experiment, this study shows that lower sugar intake early in life is linked to lower risk of heart failure and later disease onset.

Hyperbolic paraboloid molecules possess unique physicochemical properties. However, their controlled organization into well-defined superstructures remains challenging. Here, the authors report a macrocycle with hyperbolic paraboloid topology as building blocks to self-assemble a series of two-dimensional superstructures with four-level hierarchy in a controlled hierarchical manner.

NIID is a neurodegenerative disease caused by GGC repeat expansions within NOTCH2NLC gene. Here, authors develop a precise gene-editing therapy that effectively treats the disease in multiple models.

The authors create a room-temperature super relaxor critical state in a lead-free ceramic, delivering dual-high recoverable energy density and efficiency by residing at a crossover between dynamic and static/frozen polar states.

Immiscibility limits the performance of positive mixing enthalpy alloys. Here, the authors apply ultrafast sintering and quenching to fabricate mechanically interlocked Cu-Fe composites with good strength and conductivity.

Identifying jets originating from heavy quarks plays a fundamental role in hadronic collider experiments. In this work, the ATLAS Collaboration describes and tests a transformer-based neural network architecture for jet flavour tagging based on low-level input and physics-inspired constraints.

Global household material use is highly unequal: the top 10% drive roughly a third of footprints and most of the overshoot beyond safe limits. Curbing affluent overconsumption, while securing decent material floors, should be a central policy lever to cut material demand quickly and fairly.

CrSBr is an air-stable van der Waals semiconducting layered antiferromagnet, holding the promise for a variety of spintronic applications. However, like all antiferromagnets, readout and control of the magnetic structures are challenging. Here, using a graphene gate on trilayer CrSBr, Hong, Sun, and coauthors succeed in full discrimination of otherwise degenerate magnetic states and electrical control of magnetic transitions.

Two main acceleration mechanisms in the auroral acceleration region are electric potential and Alfvénic acceleration but associated energy dynamics are not completely resolved. Here, the authors show that Alfvén waves power the Earth’s auroral arc through a static potential drop in the auroral acceleration region.

Generation of orbital currents in a non-magnetic material can be useful to build efficient orbitronic devices. Now, the interplay of chiral phonons and electrons is shown to produce orbital currents in α-quartz.

Obesity poses a health challenge among middle-aged women in part driven by physiological changes associated with aging and menopause. Here the authors report a randomized controlled trial showing that a combination intervention of flexible time-restricted eating and exercise leads to greater reduction in fat mass than single interventions in women aged 40-60 years.

Liu et al. report Chinese normative lifespan brain charts showing later neurodevelopmental milestones than those detected in Western cohorts. Individual deviations from these norms are valuable in assessing clinical risk and outcomes.

Administrative-driven hierarchical management (ADHM) encourages general practitioners to act as voluntary gatekeepers in China’s non-mandatory medical system. Here the authors show that ADHM lowers cardiovascular events, mortality, and healthcare costs in atrial fibrillation patients compared with usual care.

The authors present a federated learning framework for battery fault detection in electric vehicles using charging station data. It enables privacy-preserving collaboration among data owners, creating customized models that improve fault detection accuracy and generalization across diverse data distributions.

This work demonstrates superadiabatic topological pumping on photonic chips, achieving a 20-fold device miniaturization and high-efficiency operation across a 650–920 nm bandwidth, paving the way for ultracompact integrated photonic transports.

The relationship between innate immunity and cellular senescence is unclear. Here the authors show that NRF1 promotes inflammatory signaling and suggest that NRF1 inhibition may improve age-related health outcomes.

Programable coatings are promising for information encryption, though it is challenging to design stimuli-responsive materials. Here the authors integrate a photochromic switch into a polymer system for programmable encryption.

Efforts to develop P2X7 drugs are hampered by species differences. Here, authors reveal the structural basis for these disparities and show that transgenic mice provide a powerful model for testing selective inhibitors with greater clinical relevance.

Huang, Cao and Liu compile a dataset of 3,534 profiles of members of China’s national academies to trace academic exchanges over 120 years and find evidence for a decline in foreign-educated academics.

In returning Thouless pumping, the quantized charge is pumped during the first half of the cycle and returns to zero during the second. Here, authors demonstrate returning Thouless pumping experimentally with a symmetry-protected delicate topological insulator, made of a two-dimensional acoustic crystal.

The rapid preparation of highly crystalline covalent organic framework membranes is challenging. Here, the authors show a reverse-phase microemulsion interfacial polymerization to rapidly prepare large-area covalent organic framework membranes in tens of seconds applied to protein desalination.

Ubiquitin tagging controls protein fate, but how the COP1-DET1 E3 ligase works was unclear. Here, the authors present cryo-EM structures of an inactive stacked assembly that switches to an active dimer on substrate binding, with DET1 guiding enzymes to start and co-workers to extend ubiquitin chains.

This study identifies four distinct polycystic ovary syndrome (PCOS) subtypes using unsupervised clustering analysis on data from 11,908 women and validated across five diverse cohorts. The subtypes show unique clinical features and suggest that subtype-specific management could enhance treatment precision for PCOS.

HOXA2 expression was inhibited by aberrant hypermethylation, leading to decreased SIRT1 levels, which could increase ATF6 acetylation and activation as well as subsequent ER stress, resulting in renal damage in CKD-related fibrosis.

Elebsiran plus PEG-IFNα improved hepatitis B surface antigen (HBsAg) loss rates compared with PEG-IFNα alone in patients with chronic hepatitis B virus infection. Furthermore, prior response to the BRII-179 vaccine was associated with higher HBsAg clearance, suggesting its potential as a predictive tool for identifying patients more likely to benefit from therapies.

Divalent cation–exchanged zeolites enable complete ambient NO₂ removal with zero NO emission, overcoming a long-standing challenge in air purification and establishing a scalable pathway for zero-emission NO_x filtration.

Urea electrooxidation can lower the energy demand of hydrogen production but is limited by slow reaction rates and poor durability. We design a robust Ni-Co-Mn trimetallic catalyst that sustains industrial-scale currents while efficiently driving the urea oxidation reaction.

Perovskite solar cells with carbon electrodes offer advantages in terms of stability and manufacturing cost, but their performance remains limited. Now Wang et al. report an efficiency of 23.6% by doping the hole transport layer with graphene oxide.

Global material use is rising unsustainably, but its distribution across individuals remains unclear. A study now reveals deep inequality in household material footprints, especially for non-renewable resources, and suggests that curbing overconsumption among the wealthy is key to sustainability.

Developing high-performance plasmonic photocatalyst for CO₂ reduction is challenging. Here, the authors report a Bi/Bi₂O₃ Ohmic junction with local surface plasmon resonance effect induces a robust built-in electric field, achieving efficient CO₂ photoreduction to CH₃OH.

Binding of particles to molecular or macroscopic objects generates a universal entropic pulling force. Simulations and experiments on vibrating bead-chains and DNA with multivalent ions confirm this entropic pulling effect, with implications for cellular disassembly processes and molecular machine design.

This study presents LoopID, which profiles proteins at targeted interacting enhancer–promoter (E-P) pairs, identifying the histone demethylase JMJD2 as a regulator of E-P interactions through biomolecular condensate formation independent of its catalytic activity.

Hydrogen oxidation in alkaline media is limited by slow reaction kinetics. Here, the authors develop a family of bimetallic catalysts by theoretical analysis and reveal that RuIr achieves superior activity and durability through synergistic adsorption of hydrogen and hydroxyl intermediates.

This study provides prognostic models for clinical translation and reveals methylation biomarkers and mechanisms of CAD adverse outcomes.

It is unclear how early-life urbanicity influences adult neurobehavioral traits. This study reveals that earlier menarche mediates the relationship between early-life urbanicity and adult neurobehavioral traits associated with mental disorders.

The authors present SVclone, a computational method for inferring the cancer cell fraction of structural variants from whole-genome sequencing data.

A cross-ancestry GWAS meta-analyses of brainstem structures identify 713 associations. It reveals shared/distinct genetic architectures across ancestries/substructures and overlaps with neuropsychiatric disorders and physiological functions.

Fabricating geometrically complex piezoceramics in compact sintered bodies has been difficult to achieve. Here the authors demonstrate a gravity-driven sintering strategy where high-temperature viscous behavior of piezoceramic allows for forming of complex shaped sintered bodies.