Search

A fully integrated flexible solar-thermoelectric generator is demonstrated utilizing Ag₂Se thin films as both efficient photothermal absorber and thermoelectric generators. The device delivers a power density of 0.17 μW cm^-2 under 1-sun illumination, attributed to enhanced photothermal conversion efficiency.

Uncontrollable volume expansion hinders alloy anodes in Na-ion batteries. Here, authors demonstrate in situ-formed C-N anchors embedded in Sn-based electrodes. This structure enables self-reconstruction and viscoelastic interphases, achieving long-cycle stability over 7000 cycles with high capacity.

It was shown that early-day stem cell infusions reduced the severity of acute graft-versus-host disease (aGVHD). Our result suggested early morning cord blood transplantation reduces aGVHD severity and correlated with circadian sCD26 fluctuations.

Dissolved Fe(II) could greatly enhance uptake of dissolved phosphorus by common phyllosilicate minerals in the Archean and Proterozoic ferruginous oceans, serving as a key mediator in early phosphorus cycling and habitability

Solid additives are typically used for improving morphology and efficiency in organic solar cells (OSC). Here, the authors present 3-AR, which optimizes the active layer morphology in all-small-molecule OSCs through selective interactions, achieving a PCE of 18.43% (certified 18.16%).

Dietary capsaicin alleviates Alzheimer’s disease-like pathologies in 5xFAD mice via reshaping gut bacteria and elevating the production of lipid metabolites 24-hydroxycholesterol.

Here they show that NONO collaborates with HOXA1 to modulate gene expression during early cardiomyocyte differentiation. This interaction facilitates activation of the Wnt signaling pathway, establishing the NONO-HOXA1-Wnt axis as a key mechanism in cardiac development.

Multi-axis atropisomers are common, but techniques for structural elucidation are limited. Here, the authors report a correlation between molecular dynamics and electronic through-space conjugation (TSC), along with absolute separation of the syn and anti conformers.

The authors report an omnidirectional, strain-invariant MXene-based electronic system enabled by microgrid stiffness engineering, maintaining less than 5% performance variation under 40% tensile strain for battery-free physiological and blood pressure monitoring.

The work highlights the role of solvent-mediated ionicity in modifying surface hardness of Mg-Ni-Y alloy, which facilitates the production of nanoparticles ~88 times smaller than milled powder without solvent processing, resulting in a scalable production method for metallic nanoparticles.

The efficiency of selenium photovoltaics is hindered by the poor crystallization of the Se film. Wen, Li, Lu and colleagues use light to initiate Se crystallization, suppressing dewetting and enabling the formation of a continuous film, which achieves a certified efficiency of 10.3%.

High-resolution satellite data enables a unique verification of national methane emissions worldwide. Global estimates are 63 Tg a⁻¹ for oil-gas, 30% higher than the UNFCCC reports due to under-reporting by four largest emitters, and 33 Tg a⁻¹ for coal, consistent with previous estimates.

Although heat is a major stroke risk factor, targeted intervention tools are lacking, so we developed and evaluated a Stroke Heat Risk Model for personalized prevention. Here, the authors show that it yields three times the preventable heat-attributable stroke deaths of current heat warning systems.

Controlled dislocation self-assembly is demonstrated in discontinuous-columnar Bi(Fe,Mn)O₃ thin film. Guiding dislocations along grain boundaries tailors polarization homogeneity, revealing a microstructure-driven design principle for ferroelectrics.

DNA demethylation enzyme TET1 is a known oncogene in leukemia. Here, the authors discover that TET1 is involved in GPX4-dependent and -independent ferroptosis in acute myeloid leukemia via the regulation of GSH synthesis enzyme GCLC and BH4 synthesis enzyme GCH1.

Plastic foams are widely used across industry, but petroleum-based materials are unfavorable. Here the authors report a cellulose-based molecular foam for thermal management as an environmentally friendly alternative.

NIID is a neurodegenerative disease caused by GGC repeat expansions within NOTCH2NLC gene. Here, authors develop a precise gene-editing therapy that effectively treats the disease in multiple models.

This study finds that plastic mulch substantially increases crop yields but also contaminates soils and pollutes the environment. The authors propose biodegradable films, AI-driven farming, and policy reforms to address the productivity–sustainability trade-offs.

This study shows that excessive atmospheric nitrogen deposition can enhance methane production and emissions by impacting microbial phosphorus acquisition due to the change of N/P ratios in oxygenated surface oceans.

Acne is a common skin disease caused by the anaerobic Cutibacterium acnes. Here, the authors report a microneedles patch loaded with near infrared-driven self-oxygenating ZnO₂@PDA-MnO₂ nanomotors for photothermal therapy of acne.

Large-effect variants in autism remain elusive. Here, the authors use long-read sequencing to assemble phased genomes for 189 individuals, identifying pathogenic variants in TBL1XR1, MECP2, and SYNGAP1, plus nine candidate structural variants missed by short-read methods.

CO₂ conversion to CH₃OH under mild conditions is of particular interest yet rather challenging. Here, the authors report a sun-simulated-driven tandem catalytic system comprising CO₂ electroreduction to syngas, and further photothermal conversion into high-purity CH₃OH (volume fraction <97%).

Chromatin profiling methods are often limited by a lack of suitable antibodies. Here, authors present Af-CUT&Tag, a chromatin profiling strategy based on CRISPR-integrated peptide tags which enables sensitive bulk and single-cell mapping of transcriptional regulators.

Soil life relies on microbial nutrient exchange to maintain ecosystem balance. This study shows that cobamide-producing microbes act as essential connectors in soil food webs, supporting host health and highlighting cross-kingdom links central to One Health.

Humanity’s Last Exam, a multi-modal benchmark at the frontier of human knowledge, is designed to be an expert-level closed-ended academic benchmark with broad subject coverage.

A customizable, flexible patch enables accurate three-dimensional in vivo magnetic localization across diverse medical settings and shows reliable performance in vascular and gastrointestinal studies.

Paraoxonase-1 (PON1) is a liver-specific glycoprotein that has been shown to be a tumor suppressor in hepatocellular carcinoma (HCC). Here, the authors show that PON1 reduces HCC tumor growth due to regulation of lactic acid production and regulatory T cell-mediated immunosuppression.

Fibre integrated circuits created by first preparing circuitry on extremely thin and flexible substrates and then mechanically rolling them up demonstrate microdevice density reaching 100,000 transistors per centimetre and excellent stability under harsh service conditions.

Qian, Yang et al. create an AI-powered imaging tool to aid surgeons by visually highlighting cancerous regions in the lung based on structural changes in the extracellular matrix. This system detects tumors with high sensitivity and clearly outlines their edges, enabling more precise tissue sampling and surgical resection.

Zhang et al. found that histone deacetylase 1 (HDAC1) condensation is responsible for temozolomide resistance in glioblastoma by recruiting CCCTC-binding factor and remodeling chromatin in a deacetylase-independent manner. Disrupting the HDAC1 condensates with resminostat restores the sensitivity to temozolomide.

The authors consider the changing sensitivity of the leaf-onset date to temperature (S_T) for boreal deciduous broadleaf forests. S_T increased between 1982–1996 and 1998–2012—potentially linked to enhanced chilling accumulation—but this increase is underestimated in phenology models.

Defective perovskite surfaces limit solar cell efficiency. Liu et al. introduce a small amount of a polar aprotic solvent into the defect passivation solution, enabling surface reconstruction of the perovskite layer and enhancing its overall quality.

The authors show that NAT10 is upregulated with T cell antigen receptor signaling and that T cell-specific NAT10 deficiency results in diminished numbers of naive T cells, translating to an inability to mount a significant antiviral T cell response.

The Taiwan Precision Medicine Initiative recruited and genotyped more than half a million Taiwanese participants, almost all of Han Chinese ancestry, and performed comprehensive genomic analyses and developed polygenic risk score prediction models for numerous health conditions.

Magnetic fields in stellar upper atmospheres are key to understanding stellar activity and its planetary effects. Here, the authors study chromospheric magnetic fields in three M-dwarf stars using spectropolarimetric observations, finding fields reaching hundreds of Gauss with complex height-dependent structures.

Identifying jets originating from heavy quarks plays a fundamental role in hadronic collider experiments. In this work, the ATLAS Collaboration describes and tests a transformer-based neural network architecture for jet flavour tagging based on low-level input and physics-inspired constraints.

A computational workflow, LyMOI, uses LLM, knowledge graphs and other tools to facilitate ’omic analysis and hypothesis generation related to autophagy.

Seawater lithium extraction represents an innovative transformative solution that could alleviate future lithium supply concerns. In response, we propose an Albizia julibrissin-inspired adsorption-responsive photothermal ion pump for enhanced and reversible Li+ extraction from seawater.

The STAR experiment at the Relativistic Heavy Ion Collider at Brookhaven National Laboratory demonstrates evidence of spin correlations in \(\Lambda \bar{\Lambda }\) hyperon pairs inherited from virtual spin-correlated strange quark–antiquark pairs during QCD confinement.

Li, Cui, Yang, Lu, Jiang, Zhang and colleagues identify a lactate transport mechanism from tumour-associated macrophages that regulates DNA repair and immune cell infiltration, which could be targeted to enhance immunotherapy efficacy in glioblastoma models.

Spiking neural networks are generally used for sequential information and event data processing but still lack high performance. Through algorithm and hardware co-design, Zhang et al. report a State Space Model based approach to implement on compute-in memory hardware, enabling asynchronous and real-time processing capability with high energy efficiency for event sequences.

Targeting tumors with c-MYC dysregulation is very challenging due to low MYC expression and intratumor heterogeneity. Here, the authors report a MYC-based gene circuitry that enhances immunotherapy response and tumor killing in bladder cancer.